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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">RP1T</strain>
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            <end position="638"/>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="de Groot N.N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 10">RP1</strain>
        </source>
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        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="7">RP1T</strain>
        </source>
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            <dbReference type="Proteomes" id="UP000199635"/>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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            <authorList>
                <person name="de Groot N.N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 7">RP1</strain>
        </source>
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
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        <property type="gene ID" value="SAMN05428934_10523"/>
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        <property type="entry name" value="5'-Nucleotdase_C"/>
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        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
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        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
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        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
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        <location>
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            <end position="814"/>
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            <end position="506"/>
        </location>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
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        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY84016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="814" mass="87434" checksum="A9527F47D92AB4C7" modified="2017-04-12" version="1"> </sequence>
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    <name>A0A1Q2CBI7_9ACTN</name>
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        <submittedName>
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    <gene>
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <source>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9 11">RP1</strain>
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    </reference>
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                <person name="Peterson S.W."/>
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        </citation>
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        <source>
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        </source>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
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        <property type="entry name" value="Sugar_transporter_CS"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="32"/>
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            <end position="183"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
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    </evidence>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Peterson S.W."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP43523"/>
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        <property type="protein sequence ID" value="SDY86040"/>
        <property type="gene ID" value="SAMN05428934_10598"/>
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
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        <property type="entry name" value="ABC_MetN"/>
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        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
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        <property type="entry name" value="ABC_transporter-like_CS"/>
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        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="MetN_ABC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018449">
        <property type="entry name" value="NIL_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43166:SF5">
        <property type="entry name" value="PTHR43166:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09383">
        <property type="entry name" value="NIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00930">
        <property type="entry name" value="NIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="4 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="2"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP43523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY86040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="337" mass="35839" checksum="06A7EA82DD41A13F" modified="2017-04-12" version="1">MITVTDLTKVYRQGKREVRALDGVSLTVPEGSIHGIIGHSGAGKSTLVRCLTLLDRPTSGRVEINGVDLTQARSDALRTARRRIGLVFQQANLFDSRTIADNVGYPLELIGVDKAKRAERVQELLGLVGLPDSGDAYPAQLSGGMRQRVGIARALASDPDVLLFDEPTSALDPKTTNEILDLILSLKHLGNLAVLVITHEMHVVKRICDSVSLLDAGRIVESGPLVDVVNTLDGRLAEALLGIPAHNPVDEVGGTLVDVLSSGSKAATPVVAHTSRIVGSELNIVAGSVEHLAGATFSHLRISVPDGTDPQDVIDELRRQGADAKVTDPRDLLEEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBP1</accession>
    <name>A0A1Q2CBP1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lipoprotein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_00715</name>
        <name evidence="8" type="ORF">SAMN05428934_10596</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the nlpA lipoprotein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY85989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP43521">
        <property type="protein sequence ID" value="AQP43521"/>
        <property type="gene ID" value="RPIT_00715"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY85989">
        <property type="protein sequence ID" value="SDY85989"/>
        <property type="gene ID" value="SAMN05428934_10596"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00715"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="entry name" value="Lipoprotein_NlpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30429">
        <property type="entry name" value="PTHR30429"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="MetQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544390" description="Lipoprotein" evidence="6">
        <location>
            <begin position="24"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="lipid moiety-binding region" description="S-diacylglycerol cysteine" evidence="5">
        <location>
            <position position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR002854-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY85989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="267" mass="28694" checksum="B3CC9F841D942C6C" modified="2017-04-12" version="1">MRKILITLAASLAATLSLTACGADDSTLVVGASPLPHAKILEFVRDNLAEEAGIEIEIREFDDYVLPNEALASGDIDANYFQHLPYLENQMEEKGYEFAHGEGVHIEPLTLFSDRHATVEDIPDGGTVVITNDVSNQYRGLKLLESSGLLTNVPEGATVLTLTDAENPKGLQFEETMPEVVVQQLTDPAVDAAVINANFLLNAGLKADDALAVEAVEGNPYANVLVWEEGTDNAAIATLDELLHSAEVADFIKQEWPNGDVIPGNAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBP3</accession>
    <name>A0A1Q2CBP3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ESAT-6-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WXG100 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43465">
        <property type="protein sequence ID" value="AQP43465"/>
        <property type="gene ID" value="RPIT_00410"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00410"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
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        <property type="entry name" value="T7SS_ESAT-6-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06013">
        <property type="entry name" value="WXG100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03930">
        <property type="entry name" value="WXG100_ESAT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="101" mass="11530" checksum="6AFF2844161EB728" modified="2017-04-12" version="1">MREQIMSEPAGNRETMQRAAQRVESRHQQIHALQTRLQGQMAELDSRWHGRAASAFQGDYRRFDTEFERVKQGLDLIHSSLVESLREQGGRSATPIVGPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC47</accession>
    <name>A0A1Q2CC47_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Thiol-disulfide isomerase or thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_01710</name>
        <name evidence="7" type="ORF">SAMN05428934_10890</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01710"/>
    <dbReference type="EnsemblBacteria" id="AQP43683">
        <property type="protein sequence ID" value="AQP43683"/>
        <property type="gene ID" value="RPIT_01710"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02636">
        <property type="protein sequence ID" value="SDZ02636"/>
        <property type="gene ID" value="SAMN05428934_10890"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01710"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544400" evidence="4">
        <location>
            <begin position="25"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="38"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ02636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="183" mass="18758" checksum="06B87687E522ADA1" modified="2017-04-12" version="1">MRRLAAAGLSAVLLLSGCSGPSSSDGVGFEGGDGAVTILESDDRPDAPVLSGDTLDGTAVSTDDFRGSTVVVNVWGSWCAPCRAEAPELVRASEELGPEVVFLGVNTRDLDVGPALAFERSFGLTYPSIFDPKGELLLGFGQLPPKAIPSTVVIDEQGRVAARVLGEVTASTLVGIVEDVVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC59</accession>
    <name>A0A1Q2CC59_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_01835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43703">
        <property type="protein sequence ID" value="AQP43703"/>
        <property type="gene ID" value="RPIT_01835"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01835"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009218">
        <property type="entry name" value="HD_phosphohydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21174">
        <property type="entry name" value="PTHR21174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035170">
        <property type="entry name" value="HD_phosphohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="205" mass="22684" checksum="AD415CAC9CE326DF" modified="2017-04-12" version="1">MGRPLGRHRLLGGARVVIDGHEVPASVFTSLRQRWAEPHRVYHSASHLADGLKALDRLGGQPIEVLAFWGHDAVHTNTTPDDERASAVVMEDLLAGHLPLSVVEEVRRLILLTAGHSVEPGDDAGARLCDADLSGLGADWEQYARNVQGIRAELPDLSDEGWREGRAKFLAGFLERDRFYSTERGRALWEKQARANLTRELEGLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC83</accession>
    <name>A0A1Q2CC83_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoenolpyruvate--glycerone phosphotransferase</fullName>
            <ecNumber evidence="3">2.7.1.121</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_01860</name>
        <name evidence="8" type="ORF">SAMN05428934_108120</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:18381"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:16016"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.7.1.121"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.1.121" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ03243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01860"/>
    <dbReference type="EnsemblBacteria" id="AQP43707">
        <property type="protein sequence ID" value="AQP43707"/>
        <property type="gene ID" value="RPIT_01860"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ03243">
        <property type="protein sequence ID" value="SDZ03243"/>
        <property type="gene ID" value="SAMN05428934_108120"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01860"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047324">
        <property type="term" value="F:phosphoenolpyruvate-glycerone phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00367">
        <property type="entry name" value="PTS-HPr_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.510">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039643">
        <property type="entry name" value="DhaM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012844">
        <property type="entry name" value="DhaM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000032">
        <property type="entry name" value="HPr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035895">
        <property type="entry name" value="HPr-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004701">
        <property type="entry name" value="PTS_EIIA_man-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036662">
        <property type="entry name" value="PTS_EIIA_man-typ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001020">
        <property type="entry name" value="PTS_HPr_His_P_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38594">
        <property type="entry name" value="PTHR38594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03610">
        <property type="entry name" value="EIIA-man"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00381">
        <property type="entry name" value="PTS-HPr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00107">
        <property type="entry name" value="PHOSPHOCPHPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53062">
        <property type="entry name" value="SSF53062"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55594">
        <property type="entry name" value="SSF55594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02364">
        <property type="entry name" value="dha_pts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01003">
        <property type="entry name" value="PTS_HPr_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51096">
        <property type="entry name" value="PTS_EIIA_TYPE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51350">
        <property type="entry name" value="PTS_HPR_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00369">
        <property type="entry name" value="PTS_HPR_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PTS EIIA type-4" evidence="5">
        <location>
            <begin position="2"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="HPr" evidence="6">
        <location>
            <begin position="149"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ03243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="236" mass="24204" checksum="962C67D41A26BC02" modified="2017-04-12" version="1">MAVGIVLVSHSARLAEAVVEMAMEMIHDDAPPVALAAGMPDGGLGTDATRVMSAIEEVDQGEGVVVFVDIGSAIMSAELGAELYGERPDIRVLAAPFVEGVLAAMVRSATDASLDEVAAEALSALRPKLAALGTVEEMAAEPESRRSAEVRAEATLVNDTGLHARPAAMFVAEAKRHDADVLVSKGVQGPVPAKSSIGLATLGARKGDTLHLEASGPDAQAAIDALVRFIESGFGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCA5</accession>
    <name>A0A1Q2CCA5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sirohydrochlorin ferrochelatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01970</name>
        <name evidence="4" type="ORF">SAMN05428934_11610</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000016">
        <property type="protein sequence ID" value="SDZ20294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01970"/>
    <dbReference type="EnsemblBacteria" id="AQP43727">
        <property type="protein sequence ID" value="AQP43727"/>
        <property type="gene ID" value="RPIT_01970"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ20294">
        <property type="protein sequence ID" value="SDZ20294"/>
        <property type="gene ID" value="SAMN05428934_11610"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01970"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002762">
        <property type="entry name" value="CbiX-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01903">
        <property type="entry name" value="CbiX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ20294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="226" mass="24316" checksum="9B3F4E1B2D95B02D" modified="2017-04-12" version="1">MPDIVIIARGSSDPRHAADVELLADRVRDRVRSGRGVGACFLDHHSPSPDDLAAELRHRAVVVPIMVTPSDELHTELSEVARRLGAGGADIKVAPPLGPDPRLLHACEELLSAADVRPSRDTGVVALLDQRFGASDRTAIQRVFNTGQDGYRAWAVASVSDTNDLEAVIGQLRARCERVVAVPLSLMDVRRRRELAMRCRDAQVGMVPGSLATTQALADLVVARSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCB0</accession>
    <name>A0A1Q2CCB0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HPr family phosphocarrier protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Phosphocarrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
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            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
            <dbReference type="EMBL" id="SDY27925.1"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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</entry>
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        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="338"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="368"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="432"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="464"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="532"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="602"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="648"/>
            <end position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="672" mass="70215" checksum="DB97D0038C120144" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD53</accession>
    <name>A0A1Q2CD53_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">ABC-2 type transport system ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_03690</name>
        <name evidence="7" type="ORF">SAMN05428934_101340</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY32531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03690"/>
    <dbReference type="EnsemblBacteria" id="AQP44026">
        <property type="protein sequence ID" value="AQP44026"/>
        <property type="gene ID" value="RPIT_03690"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY32531">
        <property type="protein sequence ID" value="SDY32531"/>
        <property type="gene ID" value="SAMN05428934_101340"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03690"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025302">
        <property type="entry name" value="DUF4162"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13732">
        <property type="entry name" value="DUF4162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="2"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY32531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="293" mass="31768" checksum="5D884CAF0CAA8A0F" modified="2017-04-12" version="1">MLEVLEVTRRFGDLTALDRVSFTVPAGQFTGFVGGNGAGKTTAMRIIMGVLAPTSGEVRWDGAPITAADRAQFGYLPEERGLYPKQPILSQLVYLGELHGMGAREARQAGERLLARFNLADRAKDKLEKLSLGNQQRVQIAGAVIAGPKALILDEPFSGLDPDAVDEMFGLLTEFTTRGVPVLFSSHQLELVERLCDNIVILRKGEVIAAGSVEELRTSGPTHHRIVTDNDLGWLQTQPGVQVVDLDGPTAQVAFSDTATAQRVLAEALARGPVHSFGPIVRPLSEYYREVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDB1</accession>
    <name>A0A1Q2CDB1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cell division protein SepF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">sepF</name>
        <name evidence="7" type="ORF">RPIT_04050</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer. Interacts with FtsZ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">Localizes to the division site, in a FtsZ-dependent manner.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SepF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04050"/>
    <dbReference type="EnsemblBacteria" id="AQP44086">
        <property type="protein sequence ID" value="AQP44086"/>
        <property type="gene ID" value="RPIT_04050"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04050"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01197">
        <property type="entry name" value="SepF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023052">
        <property type="entry name" value="Cell_div_SepF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007561">
        <property type="entry name" value="Cell_div_SepF/SepF-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038594">
        <property type="entry name" value="SepF-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35798">
        <property type="entry name" value="PTHR35798"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04472">
        <property type="entry name" value="SepF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 5 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0717">Septation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="148" mass="16192" checksum="21B90709AEEEDC9A" modified="2017-04-12" version="1">MGLVEDGRYQDEDQYDADADFADDEELEPAPAVAPVSPLPTRRPAPAAPVVKEVADLSRIVSVRPRSYNEARVIGENFRDGIPVIMNLSDMEDGEDKRLVDFAAGLIFGLKGNIERVSSKVFLLCPQNLVVGPEDKERIASGGFFNQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDC4</accession>
    <name>A0A1Q2CDC4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04150</name>
        <name evidence="3" type="ORF">SAMN05428934_101434</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY35122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44104">
        <property type="protein sequence ID" value="AQP44104"/>
        <property type="gene ID" value="RPIT_04150"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY35122">
        <property type="protein sequence ID" value="SDY35122"/>
        <property type="gene ID" value="SAMN05428934_101434"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04150"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY35122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="61" mass="5920" checksum="01B1C0FF9711E802" modified="2017-04-12" version="1">MLLANVDSGDVRVTLQGATDALMSYGGASAALLSGVVLAAVGFGWLAVISALLIAPAGFVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDK3</accession>
    <name>A0A1Q2CDK3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-ribazole phosphatase/probable phosphoglycerate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_04705</name>
        <name evidence="2" type="ORF">SAMN05428934_101549</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY38086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04705"/>
    <dbReference type="EnsemblBacteria" id="AQP44203">
        <property type="protein sequence ID" value="AQP44203"/>
        <property type="gene ID" value="RPIT_04705"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY38086">
        <property type="protein sequence ID" value="SDY38086"/>
        <property type="gene ID" value="SAMN05428934_101549"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04705"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY38086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="221" mass="24187" checksum="E4D80E78035CA019" modified="2017-04-12" version="1">MTPRPDTQLVVLRHGETDWNRDRRFQGHADIPLNDAGRQQAVKLRSALAQWHFDAVYASPLSRALETAQLVRPGSHVVTDPRLSEIDVGSWAGLSRDEVIAEMPSYPEHYANGVDFRRSPTGERPSEMVARAMPFFDELGLQPAGASILVVSHGQLLNRVLHALLGIEGRVLGGLMNAHFSQVLHHHGAWRLLAHNVGGSSRFVPASAGGRSTPQARPAVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDK4</accession>
    <name>A0A1Q2CDK4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04590"/>
    <dbReference type="EnsemblBacteria" id="AQP44181">
        <property type="protein sequence ID" value="AQP44181"/>
        <property type="gene ID" value="RPIT_04590"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04590"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012433473" evidence="1">
        <location>
            <begin position="23"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="604" mass="66251" checksum="B7C53EB48555F5F5" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDQ4</accession>
    <name>A0A1Q2CDQ4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA pseudouridine synthase B</fullName>
            <ecNumber evidence="5">5.4.99.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">tRNA pseudouridine(55) synthase</fullName>
            <shortName evidence="5">Psi55 synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">tRNA pseudouridylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">tRNA-uridine isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">truB</name>
        <name evidence="9" type="ORF">RPIT_04610</name>
        <name evidence="10" type="ORF">SAMN05428934_101528</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>uridine(55) in tRNA = pseudouridine(55) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42532"/>
            <dbReference type="Rhea" id="RHEA-COMP:10101"/>
            <dbReference type="Rhea" id="RHEA-COMP:10102"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04610"/>
    <dbReference type="EnsemblBacteria" id="AQP44185">
        <property type="protein sequence ID" value="AQP44185"/>
        <property type="gene ID" value="RPIT_04610"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37587">
        <property type="protein sequence ID" value="SDY37587"/>
        <property type="gene ID" value="SAMN05428934_101528"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04610"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02573">
        <property type="entry name" value="PseudoU_synth_EcTruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015225">
        <property type="entry name" value="tRNA_psdUridine_synth_fam2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="PTHR13767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09142">
        <property type="entry name" value="TruB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00431">
        <property type="entry name" value="TruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TruB_N" evidence="6">
        <location>
            <begin position="26"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="TruB_C_2" evidence="8">
        <location>
            <begin position="179"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="TruB_C" evidence="7">
        <location>
            <begin position="232"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY37587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="287" mass="29903" checksum="CC76B8EB401DA587" modified="2017-04-12" version="1">MTDASGMVIVDKPSGITSHQVVGRLRRLLGTRKIGHAGTLDPMATGVLILGVNRATRLLGHLALHDKRYVATVRLGESSPTDDADGDVVPVADASHLTRQEIDAALGAQRGDVLQIPSSVSAIKVDGVRSYSRVRKGETVELKARPVTISALDVLSVRPGGATVDVELDVECSSGTYVRAIARDLGAALGVGGHLTALRRTRIGGYSLDDAVALGDEAPSLMSMAEAARRSFPVVHLTADQARDVTFGRPLALDVPGRPTGLLSPGGELLALYEPSGSGARPVAVFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDV3</accession>
    <name>A0A1Q2CDV3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0301 (AlgH) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05325"/>
    <dbReference type="EnsemblBacteria" id="AQP44304">
        <property type="protein sequence ID" value="AQP44304"/>
        <property type="gene ID" value="RPIT_05325"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05325"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003774">
        <property type="entry name" value="UPF0301"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30327">
        <property type="entry name" value="PTHR30327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02622">
        <property type="entry name" value="DUF179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="188" mass="20093" checksum="85A63EB81A0E8911" modified="2017-04-12" version="1">MVQHTGALAAGQLLVATQPGRGGYFDRSVVLILEHNLEATVGVCLNLPTDTPVADVVAPFADKASVPAVIFEGGPVNNEIAVTLGEPATPESPPPGWQQIVGDIGVVDMSFPPELIDTSFAQLRVFVGLASWAPGQLEAELIRGSWFRSHARPEDVFGDPEGIWRRVLRRMGGGAGRWSTWSDDPTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDZ1</accession>
    <name>A0A1Q2CDZ1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05450</name>
        <name evidence="4" type="ORF">SAMN05428934_10337</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY66064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44326">
        <property type="protein sequence ID" value="AQP44326"/>
        <property type="gene ID" value="RPIT_05450"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY66064">
        <property type="protein sequence ID" value="SDY66064"/>
        <property type="gene ID" value="SAMN05428934_10337"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05450"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY66064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="440" mass="47749" checksum="1BB5C383C2A0D4BC" modified="2017-04-12" version="1">MNYSTDPFRDRLQRLLPEAPETTTWAGTAASRGQARRMRAVSSGVVAASMAVVGVLGVQWLQDVREPLVDAVPATSAPPSADTAPSESICAIESLQSTATLDSVNEATLCVVSNGRLRAQQLDRDEATALIDELRDGRERSGSSEAHQATPTLRLHDNSGNGVVILHQGADARWLLSDEQGEWLWTPTDASQRTLAEAARVAEGDQSNEELCTTTVLARSSTESLTQGAAKVWLCSSWRYAPPEPLEGGRAAQFVSGTLTRSEECVSQPADEWLIAEYADGTRERLTIPSADCSPGVGSLTTFRDLLLEQRRATDEWASIQVPPFAKPCLASEVDSFMPLDLDRAARVLVCTGEDGVGLPADDRDRLVSELQDSASLVAGTPPRSPVRLALLWPNGERLWLRDGGSPQTFYFVDHTGATHQWRPSPVLQQILERVRITGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDZ2</accession>
    <name>A0A1Q2CDZ2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PHP domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Putative hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05235</name>
        <name evidence="3" type="ORF">SAMN05428934_101653</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY40802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05235"/>
    <dbReference type="EnsemblBacteria" id="AQP44290">
        <property type="protein sequence ID" value="AQP44290"/>
        <property type="gene ID" value="RPIT_05235"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY40802">
        <property type="protein sequence ID" value="SDY40802"/>
        <property type="gene ID" value="SAMN05428934_101653"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05235"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010996">
        <property type="entry name" value="DNA_pol_b-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14716">
        <property type="entry name" value="HHH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="SSF47802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POLIIIAc" evidence="1">
        <location>
            <begin position="100"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY40802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="339" mass="36716" checksum="3F73DD5230437AE1" modified="2017-04-12" version="1">MTDPAEALREYAFWLERERADTYRVRAFRDAADLAEAIPEPDRPRTEAGWRELPGFGPKTAAVAAAACAGRVADSLAARREAGGTSLDPRGDALRRQLRGDLHTHTTWSDGGSSVAEMARVAESLGHEYFAVTDHSPRLRVANGLSRERLLAQWDEIDRVQAGRSVRILKGIEVDILADGGLDQGPDLLSRLDVVTASVHSDLRADSAAMTARMVAAVANPVTTVLGHCTGRKLRKDGSWRPESGFDAEIVFAACAMFGVAVEINSRPERQDPPMELIRLAGEAGCLFAIDSDAHAPGQLDFLTYGAARAAEAGIDPDRIITTWPVAKLLDHARRHTKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE08</accession>
    <name>A0A1Q2CE08_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide-methionine (R)-S-oxide reductase</fullName>
            <ecNumber evidence="2">1.8.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_05635</name>
        <name evidence="6" type="ORF">SAMN05428934_10374</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(R)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.12"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="1.8.4.12" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05635"/>
    <dbReference type="EnsemblBacteria" id="AQP44359">
        <property type="protein sequence ID" value="AQP44359"/>
        <property type="gene ID" value="RPIT_05635"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67044">
        <property type="protein sequence ID" value="SDY67044"/>
        <property type="gene ID" value="SAMN05428934_10374"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05635"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033743">
        <property type="term" value="F:peptide-methionine (R)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028427">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002579">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10173">
        <property type="entry name" value="PTHR10173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01641">
        <property type="entry name" value="SelR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00357">
        <property type="entry name" value="TIGR00357"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51790">
        <property type="entry name" value="MSRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MsrB" evidence="4">
        <location>
            <begin position="12"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY67044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="137" mass="15897" checksum="0AD4B358F8EC55A7" modified="2017-04-12" version="1">MNDYVAPLTKPDTQWRQQLSKLEYHVLREAGTEMPFTGEYTDTEDEGIYECRGCGAELFRSAEKFHSHCGWPSFFAPLAEERVRYLEDRSIPGRPRIEVRCMNCDGHLGHVFEGEGYDTPTDQRYCINSVSLRLRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE12</accession>
    <name>A0A1Q2CE12_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_05365</name>
        <name evidence="2" type="ORF">SAMN05428934_10320</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY65556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44310">
        <property type="protein sequence ID" value="AQP44310"/>
        <property type="gene ID" value="RPIT_05365"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY65556">
        <property type="protein sequence ID" value="SDY65556"/>
        <property type="gene ID" value="SAMN05428934_10320"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05365"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045596">
        <property type="entry name" value="DUF6459"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20060">
        <property type="entry name" value="DUF6459"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY65556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="131" mass="14153" checksum="CA407E5D2FB24AC6" modified="2017-04-12" version="1">MSTSVAPRRPTVVHLPNAAVARVVPPPPAVQGLIHAVVEALMGRRPLHQVRPCMAPGAFSYLSSRVDSGRYRRVRIGRARAQMPSSGAVEASVQVELAGRWVTCVLRLDAVAEKWRCTELIILEPAALQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE18</accession>
    <name>A0A1Q2CE18_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">RPIT_05710</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">RP1T</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Phospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05710"/>
    <dbReference type="EnsemblBacteria" id="AQP44369">
        <property type="protein sequence ID" value="AQP44369"/>
        <property type="gene ID" value="RPIT_05710"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05710"/>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008444">
        <property type="term" value="F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004570">
        <property type="entry name" value="Phosphatidylglycerol_P_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000847">
        <property type="entry name" value="Phos_ph_gly_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="AQP44369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="195" mass="21557" checksum="214308484BAACD62" modified="2017-04-12" version="1">MHVPTPVQEWDTDAVLTVPNVLSFIRLLGIPVFCWLILAGHDVSAVVLLMVFGVTDWFDGFLARRLKQRSALGAKLDPVADRLYILAAVIVLVIRGIVPWWFLVILLARDVMLALLVPALKRHGIVALPVNRVGKLGTMLLLVAFPLILLGAESSLGWEWAHWTGWAFAWTGAAAYWAAGTLYVRATIQLNRSDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE44</accession>
    <name>A0A1Q2CE44_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_05750</name>
        <name evidence="5" type="ORF">SAMN05428934_10397</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05750"/>
    <dbReference type="EnsemblBacteria" id="AQP44376">
        <property type="protein sequence ID" value="AQP44376"/>
        <property type="gene ID" value="RPIT_05750"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67606">
        <property type="protein sequence ID" value="SDY67606"/>
        <property type="gene ID" value="SAMN05428934_10397"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05750"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017039">
        <property type="entry name" value="Virul_fac_BrkB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30213">
        <property type="entry name" value="PTHR30213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03631">
        <property type="entry name" value="Virul_fac_BrkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="32"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY67606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="400" mass="43243" checksum="6B52D901809A7633" modified="2017-04-12" version="1">MKTILDRVVNNSVVAHILAALDRYNKRLGPQFAAAATYFTILSLVPILMLSFAALGLTLTVLRPELLDQIQDAVVGQLGDGDLAQKITTVIENALNNWRGIVGFALLTATYSGSNWVGNLKRAVRVMWYDKFSDASEKKNFFLELAINLAIFLGVLLCVILGVGVAQVGNAFSRQVVEFLGWEDVPGIGFLWGALTVGLTFLVSWILFAFLFTVLPQKRVRLKAWLIGTLIGAFVVTIIQSLAGRIMRLFSNNPAAQVFGPTIIVMLLFNILATLILMTAAWVGTDGTWRAERTAKLADKQPGGLDDSGLDPDEELELVGRRASRRWAAAKSLDDLRRADAVVEPSTTRYVREDVAARTVGAGLTVGYSMGAATGLGLGALLTAAIGVVARALRKNNARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE53</accession>
    <name>A0A1Q2CE53_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05895"/>
    <dbReference type="EnsemblBacteria" id="AQP44404">
        <property type="protein sequence ID" value="AQP44404"/>
        <property type="gene ID" value="RPIT_05895"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05895"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13443">
        <property type="entry name" value="HTH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="25"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="79" mass="8564" checksum="C95307E244A6BB25" modified="2017-04-12" version="1">MPDERGVVVGLDERGRERDGELAAERGLTLTELAERVGISLVNLSVLKNDRARAIRFTTLIALCDALGCQPGDLFELAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE64</accession>
    <name>A0A1Q2CE64_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl esterase/lipase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05855</name>
        <name evidence="3" type="ORF">SAMN05428934_103119</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05855"/>
    <dbReference type="EnsemblBacteria" id="AQP44396">
        <property type="protein sequence ID" value="AQP44396"/>
        <property type="gene ID" value="RPIT_05855"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68187">
        <property type="protein sequence ID" value="SDY68187"/>
        <property type="gene ID" value="SAMN05428934_103119"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05855"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_3" evidence="1">
        <location>
            <begin position="83"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY68187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="334" mass="35918" checksum="028575CA0B013744" modified="2017-04-12" version="1">MGAAADDANPPVNPLMRAILGLFSAPRINMREDYEKVRRAQRALSWVPRDPDRILDRSVTAQAGHKIPLRIFLPKSSTGEGVLLFFHGGGWTIGDIDTYSATCRTMAELTGRVVCSVGYRLAPEHPYPAALEDCLEVAETLLTDPALAGAARPEDITLIGDSAGGNLVAAVALALRGRGSALPGAQILFYPVTQWDHDPATSPYRSVAHYGTGLRLTAVEVQDYVAMYQPDPELRLSPLISPLLAEDLSGLPRALVVTAEYDLLRDEGEAFGHALRAAGTPTRIERIDGALHGFIGLPRLSRHVTTAYQLVTDFLDGNLADSRPPPSPSAGRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE72</accession>
    <name>A0A1Q2CE72_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05860</name>
        <name evidence="3" type="ORF">SAMN05428934_103120</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05860"/>
    <dbReference type="EnsemblBacteria" id="AQP44397">
        <property type="protein sequence ID" value="AQP44397"/>
        <property type="gene ID" value="RPIT_05860"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68213">
        <property type="protein sequence ID" value="SDY68213"/>
        <property type="gene ID" value="SAMN05428934_103120"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05860"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY68213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="472" mass="52911" checksum="88BB9297F18FB7F4" modified="2017-04-12" version="1">MTRVSAQRRPWVRLDNAANIFLAARSDVDSKVFRLAAELDEPIDPEVLQEALDRVYAQYPLFSAVLRQGVFWYYLQQSDLRPSVAEETGPPVQHLYHHQRHDLLFRVLYRGRRISVEVFHALTDGTGALWFFEDLLTEYVGLRHVEEFRTVQGATELKQDFTVDAFTHWFRSSSAPVTFEDDATAAVESPSTELPAEVDDGPPTTTRRRHRRRDVLRGTHSPDLRTRVIELSMPVGPVLRLAKAEGVSLTIYLLAVFFDSVRRTQVPAQSLPRTLTCSVPVNLRQFFPTASGRNFFATTLLAHTYTGDSGEDSISGVCADLDRQFRQVLTKEGLARKIRRLVRFERNPALRIIPRPLKDVILASVNALSNRGITLAISNLGRVVLPEPVARHTGRLYLHVAAVRPQFGAVSHGDQLTISFTSPFIETDYHAAFVRHLTSAGIPVEITASRVTADELAEVAGPTDHDMEATDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE95</accession>
    <name>A0A1Q2CE95_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Probable primosomal protein N'</fullName>
            <ecNumber evidence="9">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP-dependent helicase PriA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">priA</name>
        <name evidence="12" type="ORF">RPIT_06145</name>
        <name evidence="13" type="ORF">SAMN05428934_103174</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the primosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the helicase family. PriA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY69547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06145"/>
    <dbReference type="EnsemblBacteria" id="AQP44444">
        <property type="protein sequence ID" value="AQP44444"/>
        <property type="gene ID" value="RPIT_06145"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY69547">
        <property type="protein sequence ID" value="SDY69547"/>
        <property type="gene ID" value="SAMN05428934_103174"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06145"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00983">
        <property type="entry name" value="PriA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005259">
        <property type="entry name" value="PriA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041222">
        <property type="entry name" value="PriA_3primeBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042115">
        <property type="entry name" value="PriA_3primeBD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17764">
        <property type="entry name" value="PriA_3primeBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 9" id="KW-0639">Primosome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PriA_3primeBD" evidence="11">
        <location>
            <begin position="4"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="374"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP44444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY69547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="641" mass="67971" checksum="55736292EA2D6F08" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEB1</accession>
    <name>A0A1Q2CEB1_9ACTN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">RPIT_06105</name>
        <name evidence="3" type="ORF">SAMN05428934_103166</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
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            <taxon>Propionibacteriaceae</taxon>
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    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
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            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY69349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="118" mass="12412" checksum="C88C3E65136C965F" modified="2017-04-12" version="1">MKRLVPIALDLTAVVVFAVIGRASHGLDPLGVVSTAWPFLAACLIAWVALGALGNDGRGARAAIIVWLTTLLAGMALRIASGDTAAPAFFIVATLFLGGAFGGWRVVDLLRRRRYRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CED6</accession>
    <name>A0A1Q2CED6_9ACTN</name>
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        <submittedName>
            <fullName evidence="2">DUF948 domain-containing protein</fullName>
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        <lineage>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="RPIT_06245"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY70094"/>
        <property type="gene ID" value="SAMN05428934_103194"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY70094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="124" mass="12861" checksum="C607D5EE12B93050" modified="2017-04-12" version="1">MTPGEIAGLIAAIALCVFVALAAVPLLKLGRVLDEARIAVRDLGHNAVPVLQELKGTVGLTNEELAKLSVVTDDVSRVSGHATVVSENAAQMSTLFAATLGGPLVKTAAFSYGVRKALKGRKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEE1</accession>
    <name>A0A1Q2CEE1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histidine--tRNA ligase</fullName>
            <ecNumber evidence="4">6.1.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Histidyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">RPIT_06275</name>
        <name evidence="14" type="ORF">SAMN05428934_103200</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-histidine + tRNA(His) = AMP + diphosphate + H(+) + L-histidyl-tRNA(His)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06275"/>
    <dbReference type="EnsemblBacteria" id="AQP44467">
        <property type="protein sequence ID" value="AQP44467"/>
        <property type="gene ID" value="RPIT_06275"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70254">
        <property type="protein sequence ID" value="SDY70254"/>
        <property type="gene ID" value="SAMN05428934_103200"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06275"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015807">
        <property type="entry name" value="His-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00442">
        <property type="entry name" value="hisS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="12">
        <location>
            <begin position="20"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="424"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP44467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY70254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="447" mass="48703" checksum="FA44DEF8227B0175" modified="2017-04-12" version="1">MSRPKPLSGFPEFLPAGRIVENRVLEIVTSTFELHGFAPIETRAVEPLSQLARKGDIAKEVYVVRRLHADAADADELGLHFDLTVPFARYVLENAGHLAFPFRRYQVQKVWRGERPQEGRYREFTQADIDIVGQDALAGHHDVEIPLVALDVFEKLHRDLGLPPVQLHVNNRKLAEGFYRGLGIEDTAGVLQRVDKFDKVGPDAVTQLLTAEMGLSEAQARACVSLAGISATDESFVDDVRALGVEDPLLDAGLEELSALVRVARRSVPDRVVADLKIARGLDYYTGTVYESFLVGSEKLGSVASGGRYDSLASDGRLTFPGVGYSFGITRILAPLISKGRITASRSVPSAVLVAVDAEESRDQAIAVAGALRSRDIPVEVAPKADKFGKQIRYAERRGIPFVWFGAGYDDSVKDIRTGAQTAADPAIWSPPDGDLRASVSMDGNER</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEJ1</accession>
    <name>A0A1Q2CEJ1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP synthase subunit beta</fullName>
            <ecNumber evidence="11">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP synthase F1 sector subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">F-ATPase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">atpD</name>
        <name evidence="13" type="ORF">RPIT_06665</name>
        <name evidence="14" type="ORF">SAMN05428934_110114</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ10289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06665"/>
    <dbReference type="EnsemblBacteria" id="AQP44534">
        <property type="protein sequence ID" value="AQP44534"/>
        <property type="gene ID" value="RPIT_06665"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ10289">
        <property type="protein sequence ID" value="SDZ10289"/>
        <property type="gene ID" value="SAMN05428934_110114"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06665"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01347">
        <property type="entry name" value="ATP_synth_beta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005722">
        <property type="entry name" value="ATP_synth_F1_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01039">
        <property type="entry name" value="atpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0139">CF(1)</keyword>
    <keyword evidence="11" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA" evidence="12">
        <location>
            <begin position="160"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="168"/>
            <end position="175"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP44534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDZ10289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="483" mass="52776" checksum="B10503A9CF83E5CD" modified="2017-04-12" version="1">MTATASDTAQATTGGVGRVARVIGPVVDVEFAADQIPEIGNALLVDTEVMGEKRTMTMETALHVGENLVRAIALKPTDGMRRGAEVRDTGAPIKVPVGDITKGHVWNVTGDVLNVDPSTIEITERWPIHRPAPKFDALESRTEMLETGIKVLDLLTPYVKGGKIGLFGGAGVGKTVLIQEMIYRIAHNFGGTSVFAGVGERTREGNDLINEMEEAGVLKDTALVFGQMDEPPGTRLRVALSALTMAEYFRDVQNQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPNLADEMGQLQERITSTKGHSITSMQAIYVPADDYTDPAPATTFAHLDATTELSREIASRGLYPAVDPLTSSSRILDPQYIGQDHYDTAVRVKQILQRNKELQDIIAILGIDELGEEDKIIVNRARRIQQFLSQNTYMAEKFTNIPGSTVPLADTIEAFQMIVRGDVDHIAEQAFFNVGGMDDVMANWSKIQKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEJ4</accession>
    <name>A0A1Q2CEJ4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_06625</name>
        <name evidence="2" type="ORF">SAMN05428934_103271</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY72197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44526">
        <property type="protein sequence ID" value="AQP44526"/>
        <property type="gene ID" value="RPIT_06625"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY72197">
        <property type="protein sequence ID" value="SDY72197"/>
        <property type="gene ID" value="SAMN05428934_103271"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06625"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY72197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="91" mass="10105" checksum="85E34A056F51594B" modified="2017-04-12" version="1">MARRQSKHLRAPRPLLAGGAQRRVVRSGVEYIVRAVPAGRAQKEYRCPGCQQRVAPGTAHVVAWPSVAPYGADEGIEARRHWHTHCWGASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEK2</accession>
    <name>A0A1Q2CEK2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Threonylcarbamoyl-AMP synthase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06715</name>
        <name evidence="3" type="ORF">SAMN05428934_110104</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ10100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06715"/>
    <dbReference type="EnsemblBacteria" id="AQP44544">
        <property type="protein sequence ID" value="AQP44544"/>
        <property type="gene ID" value="RPIT_06715"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ10100">
        <property type="protein sequence ID" value="SDZ10100"/>
        <property type="gene ID" value="SAMN05428934_110104"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06715"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00057">
        <property type="entry name" value="TIGR00057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YrdC-like" evidence="1">
        <location>
            <begin position="15"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ10100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="215" mass="22193" checksum="F18E7841E962F774" modified="2017-04-12" version="1">MTEPARVYSLPADEANALTDAAEAVRAGQCIVLPTDTVYGIGANAFDGDAVQRLLDAKERGRDMPPPVLIAEPSMLRAIADDIPAAATALAKAFWPGALTLILKAQPKSGMNLGDTGGTVAVRVPDHDGARALLRRTGPLAVSSANVSGQPAATTADEAREQLGDRVAVYLDAGPVAGGVASTIVDFASSSEGRILRQGALELDQLREIAPEIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEL9</accession>
    <name>A0A1Q2CEL9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_06765</name>
        <name evidence="9" type="ORF">SAMN05428934_11094</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyltransferase 87 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06765"/>
    <dbReference type="EnsemblBacteria" id="AQP44553">
        <property type="protein sequence ID" value="AQP44553"/>
        <property type="gene ID" value="RPIT_06765"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09929">
        <property type="protein sequence ID" value="SDZ09929"/>
        <property type="gene ID" value="SAMN05428934_11094"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06765"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018584">
        <property type="entry name" value="GT87"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09594">
        <property type="entry name" value="GT87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="295"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="386"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ09929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="425" mass="45628" checksum="8F8A371D5B3BDDD3" modified="2017-04-12" version="1">MSLRTWLVPFGLIALFLSTRLAILIALELPEVAFVANDISYYGYHLYHLEAGEPDVMREYPVPAVWILQGIYAIGGGWQTWGPWYRAVFILLDALVAITLYRRGNASGALFWILFTGAQGAILWYRFDLIPAALVAWACLLATTFPRAAGAMVGIGAAVKLWPALLIGPLLAPDPLRDAGSRRRLAGFVVAGFGLAAASLATSGWERSASPISWQSDRGLQIESVPASPLMLLRTFTDNPSWHIELTPFNALEIVTGPGIGVMLSVSTVLTALSVLLAVALSYRLIRNLRSGDPRLPEAIVLAVLTIVLAMIVSNKTLSPQYISWLGGPVAALLVTRHSGWLHRHVEVLAVSMIVVGALTQFTYPWGAYGIMAIPLGSGPETAVLLLRNASLVVLLVYSLVLTLRASAGGVPAPPRRSAAPLQVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CER0</accession>
    <name>A0A1Q2CER0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal protein S12 methylthiotransferase RimO</fullName>
            <shortName evidence="7">S12 MTTase</shortName>
            <shortName evidence="7">S12 methylthiotransferase</shortName>
            <ecNumber evidence="7">2.8.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Ribosome maturation factor RimO</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rimO</name>
        <name evidence="12" type="ORF">RPIT_07115</name>
        <name evidence="13" type="ORF">SAMN05428934_11021</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[sulfur carrier]-SH + AH2 + L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 2 S-adenosyl-L-methionine = 3-methylsulfanyl-L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:37087"/>
            <dbReference type="Rhea" id="RHEA-COMP:10460"/>
            <dbReference type="Rhea" id="RHEA-COMP:10461"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:29961"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:73599"/>
            <dbReference type="EC" id="2.8.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="7">Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the methylthiotransferase family. RimO subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.4" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07115"/>
    <dbReference type="EnsemblBacteria" id="AQP44612">
        <property type="protein sequence ID" value="AQP44612"/>
        <property type="gene ID" value="RPIT_07115"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08418">
        <property type="protein sequence ID" value="SDZ08418"/>
        <property type="gene ID" value="SAMN05428934_11021"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07115"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103039">
        <property type="term" value="F:protein methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018339">
        <property type="term" value="P:peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01865">
        <property type="entry name" value="MTTase_RimO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005840">
        <property type="entry name" value="Ribosomal_S12_MeSTrfase_RimO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041582">
        <property type="entry name" value="RimO_TRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43837">
        <property type="entry name" value="PTHR43837"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18693">
        <property type="entry name" value="TRAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
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    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 7 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="10">
        <location>
            <begin position="8"/>
            <end position="124"/>
        </location>
    </feature>
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            <end position="411"/>
        </location>
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        <location>
            <position position="17"/>
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        <location>
            <position position="53"/>
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            <name>[4Fe-4S] cluster</name>
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        <location>
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        <ligand>
            <name>[4Fe-4S] cluster</name>
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            <name>[4Fe-4S] cluster</name>
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    </feature>
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        <source>
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        </source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
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        </source>
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        </source>
    </evidence>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP44612.1"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="475" mass="50767" checksum="17489DCE92D8F92A" modified="2017-04-12" version="1">MTSMTTTHSVHIASLGCARNDVDSEELAARLEDGGFVLVDDPERAETVVVNTCGFVDQAKKDSIDTLLAAADLKDTAGVKSVVAVGCMAERYGAQLAAELPEADAVLGFDDYAQIADRLRSILGGERHEAHVPRDRRRLLPLTPSARPAAASAVATPGHAPLPEGLAPASGPRPLRRRLGGGPSASLKIASGCDRRCAFCAIPAFRGSYLSRPVREVVSEARWLVEQGVREVFLVSENTSSYGKDLGSEHRLETLLPELAAIDGLDWIRVSYLQPAEIKPSMLAAMLQTPKVVPYFDLSFQHASATVLRRMRRFGSAEAFLALIEQIRRSAPTAGIRSNVIAGFPGETEADVEILRQFIVEANLDVMGVFGYSDEEGTEGATLPDHLPDDEIETRRSMLADLAIEVCESRAAERIGEDVVVLVESVDDDGVVGRAEHQAPETDGVVLLTGAARVGDLVPATVADSVGIDLTAEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEY7</accession>
    <name>A0A1Q2CEY7_9ACTN</name>
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        <submittedName>
            <fullName evidence="7">von Willebrand factor type A domain-containing protein</fullName>
        </submittedName>
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        <name evidence="6" type="ORF">RPIT_07505</name>
        <name evidence="7" type="ORF">SAMN05428934_1193</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000019">
        <property type="protein sequence ID" value="SDZ21832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07505"/>
    <dbReference type="EnsemblBacteria" id="AQP44673">
        <property type="protein sequence ID" value="AQP44673"/>
        <property type="gene ID" value="RPIT_07505"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ21832">
        <property type="protein sequence ID" value="SDZ21832"/>
        <property type="gene ID" value="SAMN05428934_1193"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:proteolysis"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-0645">Protease</keyword>
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    <feature type="domain" description="VWFA" evidence="5">
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            <end position="812"/>
        </location>
    </feature>
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        <location>
            <begin position="1049"/>
            <end position="1072"/>
        </location>
    </feature>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ21832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="1178" mass="123790" checksum="77AD92D8272ECF8E" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF23</accession>
    <name>A0A1Q2CF23_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_07685</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07685"/>
    <dbReference type="EnsemblBacteria" id="AQP44701">
        <property type="protein sequence ID" value="AQP44701"/>
        <property type="gene ID" value="RPIT_07685"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07685"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="41"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="238" mass="26337" checksum="8F75244A42C48E09" modified="2017-04-12" version="1">MTPFSSLPVREVVGDSGEDDQGWPFTMGAVRQLLSDGLELSWLTVLVGENGVGKSTIIEAIAMAYGLSPEGGSTHLRPSERPTESPLHARIRLVRGLSRSRWGYFLRAETMHGLITFLEQNPGADSRYHERSHGQAFTELLDTKLEHMSRRGGFLVLDEPEAGLSIVTQIKLANLLTELRHDGIQVLMATHSPILTATPGARIIELDDDGLNTRAWKDLMTVALYRRFLADPGYFGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF26</accession>
    <name>A0A1Q2CF26_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">IMP dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_07770</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07770"/>
    <dbReference type="EnsemblBacteria" id="AQP44716">
        <property type="protein sequence ID" value="AQP44716"/>
        <property type="gene ID" value="RPIT_07770"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07770"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="3">
        <location>
            <begin position="8"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="338" mass="35604" checksum="7BA54137804F59F4" modified="2017-04-12" version="1">MRGVIMYGPGDVRVEDRPDPTIQQPTDAIVRLTATCVCGSDLWGYRGINDPTDPQPMGHEYCGVVEAVGEDVRDISVGDFVVGGFYASCNACAHCRAGFPNGCVQHQWYDGCQAELLRVPLADGTLVATPGQPDEALVPSLLTLSDVMATGWHAAVMAGVRPGGTAVVVGDGAVGLCGVLAASQLGADRVIAMSRHASRQEVARRFGATDIVEERGDEGVARIRELTAGVGADAVLECVGTGDAMNQAIACARPGAMVGFVGVPHGVELPIGRMFSRNVGVRGGMATVRTYLPDLMERVWSGRINPGLVFDLTLGLEDAAEGYRAMDERRAIKALLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF50</accession>
    <name>A0A1Q2CF50_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Type-5 uracil-DNA glycosylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_07775</name>
        <name evidence="13" type="ORF">SAMN05428934_11820</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000018">
        <property type="protein sequence ID" value="SDZ21573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07775"/>
    <dbReference type="EnsemblBacteria" id="AQP44717">
        <property type="protein sequence ID" value="AQP44717"/>
        <property type="gene ID" value="RPIT_07775"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ21573">
        <property type="protein sequence ID" value="SDZ21573"/>
        <property type="gene ID" value="SAMN05428934_11820"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07775"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033958">
        <property type="term" value="F:DNA-deoxyinosine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10031">
        <property type="entry name" value="UDG-F5_TTUDGB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044147">
        <property type="entry name" value="UdgB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="11">
        <location>
            <begin position="94"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="13"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP44717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDZ21573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="276" mass="28908" checksum="863D005E42F8D835" modified="2017-04-12" version="1">MASVLLPHPLTGRPFASPVAPGTGWPGDTADAGTPVATTPDAVARLAATASRAELDAAVTLCRACPRLVGWREDVATTKRAAFADQPYWGRPVASFGDPDATALVVGLAPAAHGANRTGRMFTGDRSGDWLYSALHRAGLASQPYATLSGDGLELTGLRIIAPVHCAPPDNKPTTPEKATCAHWLDRDLQLSGTTVRAVMALGSIAWDAVLGSARRLAWGVPRPKPRFGHGAEATLTRPDGAPVRLVGCYHVSQQNTFTGRLTEPMLDAAIGRLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFE2</accession>
    <name>A0A1Q2CFE2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 13 15">tRNA (guanine-N(1)-)-methyltransferase</fullName>
            <ecNumber evidence="6 13 15">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">trmD</name>
        <name evidence="17" type="ORF">RPIT_08585</name>
        <name evidence="18" type="ORF">SAMN05428934_10728</name>
    </gene>
    <organism evidence="17 19">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 19" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">RP1T</strain>
        </source>
    </reference>
    <reference evidence="18 20" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">RP1</strain>
        </source>
    </reference>
    <reference evidence="17" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13 15">Specifically methylates guanosine-37 in various tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 15">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5 13 15">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13 15">Belongs to the RNA methyltransferase TrmD family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.228" evidence="6 13 15"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY96780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08585"/>
    <dbReference type="EnsemblBacteria" id="AQP44839">
        <property type="protein sequence ID" value="AQP44839"/>
        <property type="gene ID" value="RPIT_08585"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY96780">
        <property type="protein sequence ID" value="SDY96780"/>
        <property type="gene ID" value="SAMN05428934_10728"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08585"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052906">
        <property type="term" value="F:tRNA (guanine(37)-N(1))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18080">
        <property type="entry name" value="TrmD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1270.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00605">
        <property type="entry name" value="TrmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002649">
        <property type="entry name" value="tRNA_m1G_MeTrfase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023148">
        <property type="entry name" value="tRNA_m1G_MeTrfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016009">
        <property type="entry name" value="tRNA_MeTrfase_TRMD/TRM10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46417">
        <property type="entry name" value="PTHR46417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01746">
        <property type="entry name" value="tRNA_m1G_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000386">
        <property type="entry name" value="tRNA_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00088">
        <property type="entry name" value="trmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 13 15" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 13 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10 13 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 13 15" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA_m1G_MT" evidence="16">
        <location>
            <begin position="22"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="13 14">
        <location>
            <begin position="136"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000386-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="AQP44839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="SDY96780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="239" mass="26571" checksum="F2EEE6F593F6232B" modified="2017-04-12" version="1">MRLDLISIFPDYFSPLQLSLVGKAITAGLVDLNVHDLRQWTHDRHHTTDDTPYGGGAGMVMKPEPWGEAFDAMEEQSALPLTVVVPTPAGRPFDQALAYELAERQRLVFACGRYEGIDQRVIDHCSEKYELIEVSLGDYVLNGGEVAVLAIVEAVVRLLPGVIGNPASLDEESHAPGHRLLEYPNYTKPPVWRDRAVPEILLSGNHAAIANWRRERALERTRERRPDLVDDDIGNGFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFE8</accession>
    <name>A0A1Q2CFE8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Copper oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_08425</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08425"/>
    <dbReference type="EnsemblBacteria" id="AQP44817">
        <property type="protein sequence ID" value="AQP44817"/>
        <property type="gene ID" value="RPIT_08425"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08425"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13896">
        <property type="entry name" value="CuRO_3_CopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034279">
        <property type="entry name" value="CuRO_3_CopA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="PTHR11709"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010166498" evidence="4">
        <location>
            <begin position="27"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="88"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="5">
        <location>
            <begin position="183"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="6">
        <location>
            <begin position="390"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="494" mass="52799" checksum="80A4FD619F18CFEF" modified="2017-04-12" version="1">MNPMTRRHLLLGGLGAASAGLLGACSSPAPRSPSGHGGTPAIYPTPTLVPGPGRTTVEASLRPRPVTLDLGGVEASTWGYSDAGSTLVRGTAGDLFRVTVDNELSASTSVHWHGIRLHHAADGVPGVSQEPIEPGQRFVYEFVAPDPGTYFFHPHSGVQLDRALYAPLIIDDPAEPGRYDHEWVIVLDDWTDGVGRNPDDIFDELAAQDGPVSRGMGMGGHDMGGMHGGASPLGDAGDIDYPHYLINGRVPEAPLTFEGKPGDRARLRIINAGSDTIFRLALGGHTMTVTHSDGFAVQPRQTRALYLAMGERYDVTVTLSDGAFPLVARPEGKSGLALAVVRTGQGDTPTTQAQVSELDGDVLLGTTLRAAEGAGLPDGEVTDTFDVELNGQMDPYGWGVNGRKFGDHEPLEVAPGRRVRMRMTNMTMMAHPMHIHGHTWGLPGSGGLRKDTVLIAPMRTIEADLITDNPGEWMLHCHNIYHAEVGMMTTMRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFF7</accession>
    <name>A0A1Q2CFF7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Phosphoribosyl-ATP pyrophosphatase</fullName>
            <shortName evidence="10">PRA-PH</shortName>
            <ecNumber evidence="3 10">3.6.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">hisE</name>
        <name evidence="11" type="ORF">RPIT_08305</name>
        <name evidence="12" type="ORF">SAMN05428934_11514</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22828"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="3.6.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the PRA-PH family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.31" evidence="3 10"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08305"/>
    <dbReference type="EnsemblBacteria" id="AQP44800">
        <property type="protein sequence ID" value="AQP44800"/>
        <property type="gene ID" value="RPIT_08305"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19286">
        <property type="protein sequence ID" value="SDZ19286"/>
        <property type="gene ID" value="SAMN05428934_11514"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08305"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004636">
        <property type="term" value="F:phosphoribosyl-ATP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01020">
        <property type="entry name" value="HisE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008179">
        <property type="entry name" value="HisE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03188">
        <property type="entry name" value="histidine_hisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDZ19286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="87" mass="9775" checksum="5F95B2D9C70083E2" modified="2017-04-12" version="1">MKTFDQLFAQLTETARTRPEGSGTVARLDAGVHSIGKKIVEEAAEVWMAAEHESKEQAAEEISQLIYHLQVMMIALDLDLDDVNRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFJ5</accession>
    <name>A0A1Q2CFJ5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44884">
        <property type="protein sequence ID" value="AQP44884"/>
        <property type="gene ID" value="RPIT_08840"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08840"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="122" mass="12961" checksum="5639D7AC7216D060" modified="2017-04-12" version="1">MAGILSLQIGRALALAIAGHGWLWPASSSLITSSWGIITGNLTAGLPSLQGTSASPWFAWTAAATIFVATTASLLVLAVRWRASILHKGMASATQAERLLGLSRLKTHRAVIRPDLYRTGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFJ9</accession>
    <name>A0A1Q2CFJ9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type IV secretion system protein VirD4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08835</name>
        <name evidence="3" type="ORF">SAMN05428934_10777</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08835"/>
    <dbReference type="EnsemblBacteria" id="AQP44883">
        <property type="protein sequence ID" value="AQP44883"/>
        <property type="gene ID" value="RPIT_08835"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97848">
        <property type="protein sequence ID" value="SDY97848"/>
        <property type="gene ID" value="SAMN05428934_10777"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08835"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY97848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="285" mass="30254" checksum="B6D4E96C6B150BAC" modified="2017-04-12" version="1">MTRFDPTQVGWRIGTSYIPSKVRLWQPWDRTAGVIGPQGSGKTLDILTPALLQAPGAAVVTLTKPDDLLLTITARQAHGPVAVLDPFGAAPGLPELVWDPIDGCLDATVAEKRAKAFCAGTLGSGKESNDSAARFYAAEAAKVIQCYFHAAALAGLTLDDVLQWAASPRTATLPTDILRAHPMAEPHWAGLLAGAVTNTDERTAGNTKSTADQALALFATLTRALGEQQARTIKDLTNTLLIFGGSKDAGFNREISDLSAATRASVRVSKRPTSSRRPSQVTRTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFL0</accession>
    <name>A0A1Q2CFL0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_08905</name>
        <name evidence="2" type="ORF">SAMN05428934_10793</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44893">
        <property type="protein sequence ID" value="AQP44893"/>
        <property type="gene ID" value="RPIT_08905"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98127">
        <property type="protein sequence ID" value="SDY98127"/>
        <property type="gene ID" value="SAMN05428934_10793"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08905"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY98127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="431" mass="45779" checksum="8E11FC8DEB5D5FBB" modified="2017-04-12" version="1">MSVELTGGVRQEFETRPTSTGFELTGHSALRLLSVDFAEGWSHPSPLVDAAGVRLEHDTGITASVVIRSGQRLRLEVTLESALDEVVSVPGPTLRFEGERPAVAWLAGASGEVVLPSASGPGLLTQRRGVTSPADAGRAHLFEAEPWLRPRQILSSAWTYETYDGDIFDVPVEQSWLPWSRYVPRGDAVEISMPDGRVSASDGVEVIEQEGEFLLTPPGGPAEAHVWTSSGQTTIEIGSFDSVAALRSQAVASRAGLYADAVCYLIARQLTESWTHEEMLDALDRALGDLLEQPTAWAACAASIATRLGLPLAGEAAEAATKVLGHPTPDDVILLATHGLAPVELTSGGWPIGDFGRVGLEAVARIGYGRISTDGPPLRGRDVAIAKIFAAGLGESERGLRIAAYAQAAENRLLTHLTANPNPEHLAWLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFL1</accession>
    <name>A0A1Q2CFL1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH lacI-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_08970</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44906">
        <property type="protein sequence ID" value="AQP44906"/>
        <property type="gene ID" value="RPIT_08970"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08970"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="322" mass="34025" checksum="33666BB7F5669B3A" modified="2017-04-12" version="1">MRDVARAAGVSHQTVSRVLNEPDLVRSETRDRVLAVMRDLGYRRNLAARALASGHSALIGVVWTGADFFGPSRTVAGIEVAARSAGYATLVGALPADQEDAVASIIESFRDRSVDGVAVVAPHQRMFDLVRDRLEGIPTVMVGDLSPEECGCHTVSIDQQLGAELAVRHLIETGARSIAHVTGPLDWFDAAARVRGWRSALGDAGLELLDPIVGDWTPESGYAAGKTLADDLPDAVFCANDLMAVGLAAALGPDVSRVRLVGFDDIDGSAFFSPPLTTVHQPFEALGALSLETLMSVMAGEDPRPRKLAPELVIRASSSPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFL3</accession>
    <name>A0A1Q2CFL3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FAD-binding oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">FAD/FMN-containing dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_09000</name>
        <name evidence="7" type="ORF">SAMN05428934_107113</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
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    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY59754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="525" mass="54211" checksum="BC5251316B890B95" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFW1</accession>
    <name>A0A1Q2CFW1_9ACTN</name>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">SAMN05428934_102409</name>
    </gene>
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP44987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY59980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09485"/>
    <dbReference type="EnsemblBacteria" id="AQP44987">
        <property type="protein sequence ID" value="AQP44987"/>
        <property type="gene ID" value="RPIT_09485"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59980">
        <property type="protein sequence ID" value="SDY59980"/>
        <property type="gene ID" value="SAMN05428934_102409"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="DUF1707"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY59980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="290" mass="30332" checksum="B83362D5C1CEBF0C" modified="2017-04-12" version="1">MSELRPSFEERDRYLDLLSAAYADGRIDDVEFRRRTDGVLEAVTHRDAIAQFDGLPRPNVLPAVVDPRNDASHGPPAAFVRAAGQPPARLGQPQPSRRGALLAGGLAAGVGVVVLTGLVGVGRFDGPDASGWEESWVAEPVGPEFVSDEVPGSASWGNLIPEAGNAARELGLDSFHALTVDRDGLTALASAERSPGVVTEIRVGPEGGYWTEEPSVAETRGTAALQQVEEGFAQALYQAPLQVGGTASSAELLWAAGGEPLFKVICIDGALTGSATFDTMGSMISMEGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG75</accession>
    <name>A0A1Q2CG75_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">ABC-type multidrug transport system, ATPase and permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_10230</name>
        <name evidence="9" type="ORF">SAMN05428934_102259</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45122">
        <property type="protein sequence ID" value="AQP45122"/>
        <property type="gene ID" value="RPIT_10230"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55823">
        <property type="protein sequence ID" value="SDY55823"/>
        <property type="gene ID" value="SAMN05428934_102259"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10230"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 5" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="43"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="335"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY55823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="624" mass="66693" checksum="350384D047781D21" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGC2</accession>
    <name>A0A1Q2CGC2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DinB superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10365</name>
        <name evidence="3" type="ORF">SAMN05428934_102232</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10365"/>
    <dbReference type="EnsemblBacteria" id="AQP45147">
        <property type="protein sequence ID" value="AQP45147"/>
        <property type="gene ID" value="RPIT_10365"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55098">
        <property type="protein sequence ID" value="SDY55098"/>
        <property type="gene ID" value="SAMN05428934_102232"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10365"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
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        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="38"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY55098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="195" mass="21890" checksum="9BB9551DAB3D919E" modified="2017-04-12" version="1">MNQDYPPTLPDRRDWTVVIVEGCEECGYVPSNPHDSSARLAAAAAEWPEVLGSEGIRERPEPTVWSPLEYAVHARDMVRLLGARVGAMLADEDPVFEDWDGDVHAAEGRYWEADAAQIIEDIRLATRQTQSVLARVGRSDWERTGRRSDGRRFTVATLSQYLVHDVEHHLQDARLGLRVRVPLLGRPATTGPTDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGD4</accession>
    <name>A0A1Q2CGD4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10530"/>
    <dbReference type="EnsemblBacteria" id="AQP45178">
        <property type="protein sequence ID" value="AQP45178"/>
        <property type="gene ID" value="RPIT_10530"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10530"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025339">
        <property type="entry name" value="DUF4245"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14030">
        <property type="entry name" value="DUF4245"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="187" mass="20209" checksum="F6CFF082A6A5FF9E" modified="2017-04-12" version="1">MAGRNPNARSRDMFISMAVLVLPVLLVVWLFSQEGDVRPEPVDVASVVERAQTQSPYPVLYAQDLGDGWQPVRATWAASGDPFVTSEPAVGNSWQVGYLSPREVYFEVLQRDSQGDTLIADATREGARIGEGVDLAGLSWERYESGDGRTRSLVSTDGDVTSVVSADTDFAELEAFTSALVEAPPQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGG9</accession>
    <name>A0A1Q2CGG9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10690</name>
        <name evidence="3" type="ORF">SAMN05428934_102167</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY53143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10690"/>
    <dbReference type="EnsemblBacteria" id="AQP45204">
        <property type="protein sequence ID" value="AQP45204"/>
        <property type="gene ID" value="RPIT_10690"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY53143">
        <property type="protein sequence ID" value="SDY53143"/>
        <property type="gene ID" value="SAMN05428934_102167"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10690"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003695">
        <property type="entry name" value="Ppx_GppA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02541">
        <property type="entry name" value="Ppx-GppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ppx-GppA" evidence="1">
        <location>
            <begin position="30"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY53143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="304" mass="32485" checksum="F5B504234C96B1B1" modified="2017-04-12" version="1">MSAVAAVDCGTNSIRLLIIEETPDGIVEHTRQTRLARLGQGVDATGEFHPEALERANVIFDEYAGFIRQYGADRVRFVATSAARDVSNRDVFERNVEERLGVPVDVISGDEEAALSAGGVLSGVEAPTPVLVFDIGGGSTELIVIEEDRRIVSATSLDIGAVRVKERFLTTDPATDDEIAAARAYVGDLLDRAGVDFASIRTAIGVAGTVTSMAASVLGLQQYERRAVHRTVLSREDIKRSNARWLRQTAAETATEPCMHPLRASVLGAGSLIMDEISARVPGGSVLVSESDILDGIARGLLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGK3</accession>
    <name>A0A1Q2CGK3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide methionine sulfoxide reductase MsrA</fullName>
            <shortName evidence="4">Protein-methionine-S-oxide reductase</shortName>
            <ecNumber evidence="4">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
            <shortName evidence="4">Peptide Met(O) reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">msrA</name>
        <name evidence="6" type="ORF">RPIT_10595</name>
        <name evidence="7" type="ORF">SAMN05428934_102186</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY53680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10595"/>
    <dbReference type="EnsemblBacteria" id="AQP45190">
        <property type="protein sequence ID" value="AQP45190"/>
        <property type="gene ID" value="RPIT_10595"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY53680">
        <property type="protein sequence ID" value="SDY53680"/>
        <property type="gene ID" value="SAMN05428934_102186"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10595"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PMSR" evidence="5">
        <location>
            <begin position="57"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY53680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="222" mass="24949" checksum="A1BA4C06D04A511E" modified="2017-04-12" version="1">MEIDVLAWLNSRMNQTPQMVTEREALPGRDATILSPMPTHEVLGLPLDEVPTGCEVAYFALGCYWGVERLYWETDGVVNTAAGFMGGFTPNPTYRETCTGRTGHTETVRVVFDPARVSYDDLLRIFWENHDPTQVNRQGNDLGTQYRSAIFPTNDEQARAAERTRAEFQANLASEGFGSIATEIVPDQTFFYAEDEHQQYLHKNPHGYCPIHATGVKCGPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGK4</accession>
    <name>A0A1Q2CGK4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10515</name>
        <name evidence="2" type="ORF">SAMN05428934_102202</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY54191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45175">
        <property type="protein sequence ID" value="AQP45175"/>
        <property type="gene ID" value="RPIT_10515"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY54191">
        <property type="protein sequence ID" value="SDY54191"/>
        <property type="gene ID" value="SAMN05428934_102202"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10515"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY54191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="255" mass="27088" checksum="78317AA7DD725460" modified="2017-04-12" version="1">MDSPQLHALGFDFPALDDLIKAAFAAGVRGIDAVPGFDLIGHYTDPSGARIAFLKRAGQAADTTAALKSSTAYRAQVVRFTDHLARISLYADDEEGRLLTQYVSLVDDPVAYAQHDLTKAGEFTVVERLEVGALAVDVAVYEDTTAFEASPAAEMGPITVEPTSLYSPGLLGLQAGAITPAEATPTMLMGVIVQSVEVRRNELSGVEFQYVIGTTDVDLACALPMERPVAPGNVVHGLWYATASSGTWNEDTPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGR3</accession>
    <name>A0A1Q2CGR3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45235">
        <property type="protein sequence ID" value="AQP45235"/>
        <property type="gene ID" value="RPIT_10875"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10875"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="60" mass="6319" checksum="1DAD2D579B30656F" modified="2017-04-12" version="1">MRTALSPARAAAAPAGAAEPEARDFADHVRMCQSHEGFDGMHNPGVMHQGLAGWEAHHAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGV3</accession>
    <name>A0A1Q2CGV3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_11440</name>
        <name evidence="9" type="ORF">SAMN05428934_10216</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY48446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11440"/>
    <dbReference type="EnsemblBacteria" id="AQP45334">
        <property type="protein sequence ID" value="AQP45334"/>
        <property type="gene ID" value="RPIT_11440"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY48446">
        <property type="protein sequence ID" value="SDY48446"/>
        <property type="gene ID" value="SAMN05428934_10216"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11440"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="9" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="7">
        <location>
            <begin position="130"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="91"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="176"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY48446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="454" mass="46088" checksum="5392A9D95A711EA7" modified="2017-04-12" version="1">MATVVVMPQLGNSVESCLIVSWLVAVGDAVAENAIVCEVETDKASMEVPSTAAGTVLALLWDEGDDVPVKEPLLVVGAAGEDPKAALAEIGWSGAGDDGSARSTEEPAAVDDEPSAPAADDAPRTAATGASSPRARALAQANSLDIASVSEGSGPGGRVIERDVRAALSNSTAAAARAGAHGSDAAGTGIGGRITTGDLAAPTEPAAEATPATAAASGREYPGPSTATPLKGVRKVIAERMMHSLASSAQLTYTTTARAAGLLALRAKLKGSPEELGLNGVTIGDLVGFAAIKTAAKHTNHNAHLADGTLTTFENVHLGMAVDTPRGLLVPTVRNANQMSLREFSATSKELAFAAIDGRIDPDLLAGATFTVSNLGGFGIESFTPLLNVPQVAILGVDAIFPRAVIHDDGTVGAEQRIGFSLTADHRVIDGADAARFLQDLVKYVENIDITVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGV8</accession>
    <name>A0A1Q2CGV8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">TspO and MBR related proteins</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_11455</name>
        <name evidence="9" type="ORF">SAMN05428934_10212</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TspO/BZRP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY48316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11455"/>
    <dbReference type="EnsemblBacteria" id="AQP45337">
        <property type="protein sequence ID" value="AQP45337"/>
        <property type="gene ID" value="RPIT_11455"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY48316">
        <property type="protein sequence ID" value="SDY48316"/>
        <property type="gene ID" value="SAMN05428934_10212"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11455"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15904">
        <property type="entry name" value="TSPO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038330">
        <property type="entry name" value="TspO/MBR-related_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004307">
        <property type="entry name" value="TspO_MBR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03073">
        <property type="entry name" value="TspO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="7">
        <location>
            <begin position="10"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY48316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="472" mass="50061" checksum="482D0A5BF41923CD" modified="2017-04-12" version="1">MTQRTALVTGASGYVGAQLVPALLDAGWHVRVLARTPSKLQGDWRDLVEVAQGDATDPDDVRAALDGVQVAYYLLHSMDGQGDYRERDRRMAHTFAEAAVAQGVGRLVYLSGLHPEGPLSTHLASRVEVGDILLASGVPTAVLQAGVVLGDGSASFDMLRHLTERLPVAIGPKWLRNRIQPIAIDDVVHYLVRAAELDPQVNRTIDIGMDEILTYRDMMRRYARATGLLPRIIGTVPVLTPWLASHWVGVVTPVDSGIAKPLVGSLIHEAVKSEDDAATLLGDPPGGVLGFDAAVRRATDGVDPHRWSRTLFKVGAGVAATAVAGSLLTAPDSAWYRRLRKPVFQPPPVAFPVVWTALYALITVAGTATIADLHEDDRADEAQGFGRALAANLVLNAAWSGLFFRAKNPPLATAGAAVLAASSADLSRRAASAGEGKAAAFGAYAAWCTFATLLSAAVARLNPSSRSPRLPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGX1</accession>
    <name>A0A1Q2CGX1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Carbohydrate ABC transporter membrane protein 2, CUT1 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_11640</name>
        <name evidence="7" type="ORF">SAMN05428934_106147</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11640"/>
    <dbReference type="EnsemblBacteria" id="AQP45369">
        <property type="protein sequence ID" value="AQP45369"/>
        <property type="gene ID" value="RPIT_11640"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93883">
        <property type="protein sequence ID" value="SDY93883"/>
        <property type="gene ID" value="SAMN05428934_106147"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11640"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="92"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY93883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="312" mass="34385" checksum="BCE4DBD00FC13185" modified="2017-04-12" version="1">MTTTSAPLAASSSFEKRDGFLSRIADPTFNIVTVGLLLLAAAAIIYPLYFIVIASVSDPNLIAQGKVWLFPQGFTLEGYETLFKNDALVRGFGNSLLYTGVGTLVSVSIILCTGYALSRRDMPGRNFFMILFIITMFFDGGLIARYLVVRDLGLLNTMWAVILPGAVGVWNLIIARTFFETNVPAELREAAQIDGANDFRFFFKVALPLTKPLIALMAMTHIVAYWNSYFDAMIYLNDESMYPLQLVLRNVLIQSQASASLDTGSIDSYAAAQRLGELIKYGMIVVSTVPLLIIFPFLQKYFVKGATLGALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGX5</accession>
    <name>A0A1Q2CGX5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mannose-6-phosphate isomerase</fullName>
            <ecNumber evidence="4">5.3.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_11660</name>
        <name evidence="7" type="ORF">SAMN05428934_106143</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-mannose 6-phosphate = D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12356"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="5.3.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the mannose-6-phosphate isomerase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11660"/>
    <dbReference type="EnsemblBacteria" id="AQP45372">
        <property type="protein sequence ID" value="AQP45372"/>
        <property type="gene ID" value="RPIT_11660"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93806">
        <property type="protein sequence ID" value="SDY93806"/>
        <property type="gene ID" value="SAMN05428934_106143"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11660"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004476">
        <property type="term" value="F:mannose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001250">
        <property type="entry name" value="Man6P_Isoase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016305">
        <property type="entry name" value="Mannose-6-P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10309">
        <property type="entry name" value="PTHR10309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01238">
        <property type="entry name" value="PMI_typeI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00714">
        <property type="entry name" value="MAN6PISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00218">
        <property type="entry name" value="manA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY93806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="378" mass="39628" checksum="1D88E79364427C70" modified="2017-04-12" version="1">MWRMRNPRMDYAWGSAAAIPEFLGEEPTGRPVAEVWMGAHPKAPSSLVDFHGADVPLDVAIRDHPEELLGADVLTRFGPRLPFLVKLLAAGKPLSLQVHPAADLAAEGFAREEAAGLPLEASERTFKDEHHKPEVMIALAHTETLAGLRRTDASGALLERIGGPWARRVSGLLDEDDLRPALKALLSGDAWAAHRSAVLARCAELGEEDRAYALVGELDRHFPGDSGAAAPLMLNVVHYGPGEALFVPTGQIHAHISGFGVEVMAASDNVIRAGLTPKHIDREALFEALAPTPAEPLLKQTVEGSPLALPADEFQVVVGEGAVPASPAARIIVTLAPGAVAGLGDLGRGAGAFIEPLAETRAGGRALTVSVPAITGGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH35</accession>
    <name>A0A1Q2CH35_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MerR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">MerR family transcriptional regulator, heat shock protein HspR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_11915</name>
        <name evidence="4" type="ORF">SAMN05428934_10692</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11915"/>
    <dbReference type="EnsemblBacteria" id="AQP45417">
        <property type="protein sequence ID" value="AQP45417"/>
        <property type="gene ID" value="RPIT_11915"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92716">
        <property type="protein sequence ID" value="SDY92716"/>
        <property type="gene ID" value="SAMN05428934_10692"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11915"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HTH merR-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY92716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="140" mass="15570" checksum="1C3D8637B9EFB5D9" modified="2017-04-12" version="1">MTSLPQPFDPDAAVFTVSVAASLADMHAQTLRGYDRLGLVVPQRSRGRGRRYSLRDIAKLRHVQHLSQNEGINLEGIRRILALEEQVDGLRDQVERLTEMVQRLQAHGAGARLFTAESSGAVHRGRFRPAPRLALPPSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH45</accession>
    <name>A0A1Q2CH45_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycosyl hydrolase family 32</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_12005</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 32 family.</text>
    </comment>
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        <property type="protein sequence ID" value="AQP45434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12005"/>
    <dbReference type="EnsemblBacteria" id="AQP45434">
        <property type="protein sequence ID" value="AQP45434"/>
        <property type="gene ID" value="RPIT_12005"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12005"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001362">
        <property type="entry name" value="Glyco_hydro_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018053">
        <property type="entry name" value="Glyco_hydro_32_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013189">
        <property type="entry name" value="Glyco_hydro_32_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013148">
        <property type="entry name" value="Glyco_hydro_32_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08244">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PROSITE" id="PS00609">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_32N" evidence="4">
        <location>
            <begin position="26"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_32N" evidence="4">
        <location>
            <begin position="616"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_32C" evidence="5">
        <location>
            <begin position="692"/>
            <end position="846"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="945" mass="101408" checksum="80C670BFAB806A77" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH47</accession>
    <name>A0A1Q2CH47_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Monosaccharide ABC transporter ATP-binding protein, CUT2 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Sugar ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_11995</name>
        <name evidence="6" type="ORF">SAMN05428934_10676</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11995"/>
    <dbReference type="EnsemblBacteria" id="AQP45432">
        <property type="protein sequence ID" value="AQP45432"/>
        <property type="gene ID" value="RPIT_11995"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92328">
        <property type="protein sequence ID" value="SDY92328"/>
        <property type="gene ID" value="SAMN05428934_10676"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11995"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY92328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="249" mass="26743" checksum="EE35575A332E691C" modified="2017-04-12" version="1">MSEPLLEVRALDKSFGGVQALVDVDLTVGAGEVVGLVGDNAAGKSTLARTLAGVYQPDRGHIRLGGEPVSLPSTRAALDLGIAPVFQEFALVETLDVPSNLFLGRELIRADGLLDEARMEELARDYLDRLNSRIPNLRTPLSRLSAGQRQCVAIARTLVANPRIVVLDEPTASLSVSQTAEVLSHVEGLRDLGLGVILISHNLNDVRAVADRIEVLRHGRNNGSFRADEVSYEDVLGAVTGATRYPKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHA6</accession>
    <name>A0A1Q2CHA6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">D-alanyl-D-alanine carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_12335</name>
        <name evidence="5" type="ORF">SAMN05428934_1069</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY90855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12335"/>
    <dbReference type="EnsemblBacteria" id="AQP45491">
        <property type="protein sequence ID" value="AQP45491"/>
        <property type="gene ID" value="RPIT_12335"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY90855">
        <property type="protein sequence ID" value="SDY90855"/>
        <property type="gene ID" value="SAMN05428934_1069"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12335"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039561">
        <property type="entry name" value="Peptidase_M15C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13539">
        <property type="entry name" value="Peptidase_M15_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544504" evidence="2">
        <location>
            <begin position="28"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M15_4" evidence="3">
        <location>
            <begin position="566"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13539"/>
        </source>
    </evidence>
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        <source>
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    <sequence length="640" mass="67954" checksum="01B682FC043159CE" modified="2017-04-12" version="1"> </sequence>
</entry>
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</entry>
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        <property type="gene ID" value="RPIT_12855"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY78183">
        <property type="protein sequence ID" value="SDY78183"/>
        <property type="gene ID" value="SAMN05428934_104116"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12855"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="1">
        <location>
            <begin position="4"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY78183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="333" mass="35468" checksum="92A1994ABD5F5E65" modified="2017-04-12" version="1">MTVIAAGHLCMDLTPHLAGHEPGMEPGVLYAVGALKQQLGGSVANTGGTLARLGERVDVHATIGDDELGRVCRRMVEQTVSERAHLATSSLGTSYSIVIEHGGHDRTFWQYEGANADFDPRRVDLGPDVDLFHVGYPSLLPVLCRDPLALAEAFEQAKAKGITTSLDQAHVADGSVAAEVDWAGWFRQTIPHTDVWSPSWDDMTSALRLEGEPTRERLTELAYTMLGWGAAVVQLSAGSSGFVLATASRERLERAGSVLSPVAAQWADQSLWFAAESIDSPSTTVGAGDALTAGLLRAMRLGLSPDAAGAFARDVVGRHLRGEDLGSMTGERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHR7</accession>
    <name>A0A1Q2CHR7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Adenine DNA glycosylase</fullName>
            <ecNumber evidence="4">3.2.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">RPIT_13000</name>
        <name evidence="16" type="ORF">SAMN05428934_10487</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1T</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1</strain>
        </source>
    </reference>
    <reference evidence="15" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.</text>
            <dbReference type="EC" id="3.2.2.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nth/MutY family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.31" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13000"/>
    <dbReference type="EnsemblBacteria" id="AQP45610">
        <property type="protein sequence ID" value="AQP45610"/>
        <property type="gene ID" value="RPIT_13000"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY77422">
        <property type="protein sequence ID" value="SDY77422"/>
        <property type="gene ID" value="SAMN05428934_10487"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13000"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000701">
        <property type="term" value="F:purine-specific mismatch base pair DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004036">
        <property type="entry name" value="Endonuclease-III-like_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003651">
        <property type="entry name" value="Endonuclease3_FeS-loop_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004035">
        <property type="entry name" value="Endouclease-III_FeS-bd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044298">
        <property type="entry name" value="MIG/MutY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42944">
        <property type="entry name" value="PTHR42944"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10576">
        <property type="entry name" value="EndIII_4Fe-2S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00525">
        <property type="entry name" value="FES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00764">
        <property type="entry name" value="ENDONUCLEASE_III_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01155">
        <property type="entry name" value="ENDONUCLEASE_III_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="14">
        <location>
            <begin position="54"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="AQP45610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="SDY77422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="300" mass="32433" checksum="74C9E0BAAEB4874B" modified="2017-04-12" version="1">MTARTAESQPHAEADVAVDGLFAPVATWFAANARDLPWRRAETTPWGVLVSEVMCQQTPAPRVAPLWEEWMERWPTAAALADAATADVLRAWGRLGYPRRALRLQETARAVDQLGGLPKDEAGLLALPGVGRYTAAAVVAFAYGRRSLVLDTNVRRVLARADGGVEFPHRHETAAERTRAWQFVPEDDAEAALWSASAMELGALVCTAKNPRCDQCPIADRCAWRAGGYPAWSGPERTAQPWEGTDRQCRGRIMAALRASSGPVSLADVAWPDQDQLASCAESLARDGLAVRVDGGLALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHU4</accession>
    <name>A0A1Q2CHU4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribosomal protein S18 acetylase RimI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13430</name>
        <name evidence="3" type="ORF">SAMN05428934_1042</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY75018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45688">
        <property type="protein sequence ID" value="AQP45688"/>
        <property type="gene ID" value="RPIT_13430"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY75018">
        <property type="protein sequence ID" value="SDY75018"/>
        <property type="gene ID" value="SAMN05428934_1042"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13430"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY75018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="186" mass="20770" checksum="2D3EE0D218C31B44" modified="2017-04-12" version="1">MTSDSLKPEITVHTQPEVSALAELVWPTYREAFGGFPNMQSFQSELLGRHAAREGFRLVTASVAGEVVGFSWGYIGHRGQFWTELVSEALPHDVVEEWVGGHFEFAEMAVSPSFRRRGLGAFLHDHLLTDVGRRCLLSTVDDPNDPAVRLYRRAGWQRLGVLKSGTQVMGRHAETPLLTLVRQDPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHU9</accession>
    <name>A0A1Q2CHU9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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            <begin position="32"/>
            <end position="137"/>
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            <begin position="34"/>
            <end position="58"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="137" mass="13906" checksum="8F75D913D8063AD7" modified="2017-04-12" version="1">MLLIGLLAGIALAAAAGVFLLGIGWATPLKAQSVISESPTPSASPTADPTTTSSGDVSEACIRAAEYNIVVDQGVEDLARGAEEQDALILQETLDRLQEEREKADGASEECLAQAGKAPQTEGSASAEPSPSPSPTS</sequence>
</entry>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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                <person name="Schumann P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">RP1T</strain>
        </source>
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    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP45706.1"/>
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    </dbReference>
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            <begin position="62"/>
            <end position="76"/>
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            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP45706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ13226.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="194" mass="20057" checksum="4EE84B28B3206513" modified="2017-04-12" version="1">MSEPFEPNPAPPTWTAVGPDHDAAPPPIPTWAKVLGVTALALLVVLAGLLGTALGRWSPTPAPSATPSPSPSPSFELTPPVQVGEFVAGDITESAGPAPLNQRIVRASYSDGSDRLLLVLTWPEEDIDTFVTGAGIEDAQELTAGTICGTSLDTDLPACARLSGDTGLLLLAVTEQRPTVVAALLSEFERALVD</sequence>
</entry>
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    <accession>A0A1Q2CHZ1</accession>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">RP1T</strain>
        </source>
    </reference>
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        <text evidence="10">A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
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        </reaction>
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    </comment>
    <comment type="subunit">
        <text evidence="10">Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="10">Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the type II topoisomerase GyrB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the type II topoisomerase family.</text>
    </comment>
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    <dbReference type="EnsemblBacteria" id="AQP45727">
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    </dbReference>
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        <property type="component" value="Chromosome"/>
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        <property type="project" value="InterPro"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DNA_gyrase_B_C"/>
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        <property type="entry name" value="HATPase_C"/>
    </dbReference>
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        <property type="entry name" value="HATPase_C_sf"/>
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        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
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        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
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        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
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        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
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        <property type="entry name" value="TopoIIA_CS"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="9 10 12" id="KW-0413">Isomerase</keyword>
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    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0799">Topoisomerase</keyword>
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        <location>
            <begin position="463"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP45727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="685" mass="76081" checksum="34936824F023767F" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI04</accession>
    <name>A0A1Q2CI04_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_13770</name>
        <name evidence="5" type="ORF">SAMN05428934_11146</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13770"/>
    <dbReference type="EnsemblBacteria" id="AQP45741">
        <property type="protein sequence ID" value="AQP45741"/>
        <property type="gene ID" value="RPIT_13770"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12448">
        <property type="protein sequence ID" value="SDZ12448"/>
        <property type="gene ID" value="SAMN05428934_11146"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13770"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03360">
        <property type="entry name" value="LbH_AT_putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041561">
        <property type="entry name" value="PglD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020019">
        <property type="entry name" value="Sia_OAcTrfase_NeuD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17836">
        <property type="entry name" value="PglD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03570">
        <property type="entry name" value="NeuD_NnaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PglD_N" evidence="3">
        <location>
            <begin position="4"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ12448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="214" mass="22114" checksum="6B1CE408A900153F" modified="2017-04-12" version="1">MTERVVVVGASGFGREALDVLEAMQAAGAALEIVGVVDDQPSPLNLHRLSQRQIEYLGTIDDWLARDADEAYLLGIGSPPVRRMLVEKLDARSRRAFTAIHPNASVGSRADIAEGVVICAGAVVSTNVRLERHVHVNPNATIGHDSTLGEFSSLNPGGVVSGEVGIEPGVLIGATATVLQQLTVGADTTVGAGALVTKNVPSGVVVKGVPGTWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI34</accession>
    <name>A0A1Q2CI34_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized nucleotidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_13965</name>
        <name evidence="2" type="ORF">SAMN05428934_1115</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ11596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13965"/>
    <dbReference type="EnsemblBacteria" id="AQP45771">
        <property type="protein sequence ID" value="AQP45771"/>
        <property type="gene ID" value="RPIT_13965"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ11596">
        <property type="protein sequence ID" value="SDZ11596"/>
        <property type="gene ID" value="SAMN05428934_1115"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13965"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039498">
        <property type="entry name" value="NTP_transf_5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14907">
        <property type="entry name" value="NTP_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ11596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="296" mass="32974" checksum="58E60AEDB88787B3" modified="2017-04-12" version="1">MAELPTLPIPLRVHLAHATVQAIADEASADVLHIKGPAVAPALRPEGRSSADADVLIRPAHLHRLLSGLRRHGWHQVTGLHSTDLIRHSTNWYHPQLGQLDVHVRFPGIQAPAERAFDVLWRERGQQNVAGRPCVVPSVTGQRLILLLHAARSLQANAADIRAAWRTASDAERGQTLALARELQAEVALASATGDLDQYRDRPEYALWQLYAENRTTTTGFRRIAAELKAAPADLRFVRLRLGWYAAGVVVRTPQRLTADLARRPTLREVAAAYGQLVRRGRDLVVRRRPVRRDRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI52</accession>
    <name>A0A1Q2CI52_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase involved in cell wall bisynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13835</name>
        <name evidence="3" type="ORF">SAMN05428934_11133</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13835"/>
    <dbReference type="EnsemblBacteria" id="AQP45753">
        <property type="protein sequence ID" value="AQP45753"/>
        <property type="gene ID" value="RPIT_13835"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12198">
        <property type="protein sequence ID" value="SDZ12198"/>
        <property type="gene ID" value="SAMN05428934_11133"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13835"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="6"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ12198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="333" mass="37188" checksum="2E6CCDBDC4785DD5" modified="2017-04-12" version="1">MPGTVSVIVPVYNAEAHLPKCLASLAGQTYRDLEIILVDDGSTDRSLQMLEAFAAEDTRARVVTQKNAGVSRARNVGLASAQGDYVSFVDSDDWLEPETYASVVGAFDGNDIDFVSFQYFVDQAAESVAYGISGRFHGLHGTVTGLEAVLETTNRFVWTRVFRRELIGPTRFREDLHWGEDTVFVIEVARRARWSFLIPDPYYHYVQSKDSATRSKVNPKRLTGIEMTHVLQRMVEEAAPHLAPFVVATRANIFATLAQDAYAQPRRDWTPEIPTLIKTIRTESSKIVLARGLGMSTRLKAGTLAVSPMLFVRLNQLRLERLSGRARQGVRQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI81</accession>
    <name>A0A1Q2CI81_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">UDP-N-acetyl-D-galactosamine dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Vi polysaccharide biosynthesis protein VipA/TviB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_14040</name>
        <name evidence="6" type="ORF">SAMN05428934_11712</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000017">
        <property type="protein sequence ID" value="SDZ20901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14040"/>
    <dbReference type="EnsemblBacteria" id="AQP45783">
        <property type="protein sequence ID" value="AQP45783"/>
        <property type="gene ID" value="RPIT_14040"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ20901">
        <property type="protein sequence ID" value="SDZ20901"/>
        <property type="gene ID" value="SAMN05428934_11712"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14040"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="UDP_ManNAc/GlcNAc_DH"/>
    </dbReference>
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        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0520">NAD</keyword>
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    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="4">
        <location>
            <begin position="318"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDZ20901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="425" mass="46517" checksum="1BAE7B168045D351" modified="2017-04-12" version="1">MQRVEDVKIAVIGLGYVGLPLAVEFGKQLPVVGFDINHRRIDELKDGTDRTLEVTAEEFASVQSLSFTADAADIADCTVFIVTTPTPIDEHKRPDLTPLLSATRTVAAVLKPGDVVIYESTVYPGATEEDCVPILEEISGLTFNEDFFAGYSPERINPGDKEHRVSTIVKVTSGSTPEAADFVDELYRRIITAGTHKAPTIKVAEAAKVIENTQRDVNIALMNELAILFGKLGIDTHDVLAAAGTKWNFLRFTPGLVGGHCIGVDPYYLTHKAQQVGHHPEIILAGRRINDSMGPWVASQMVKLMSKAGVPINGSRVLILGLTFKENTPDLRNTRVVDIISELEGYGINVDVNDPWADPAEAELYYGLQLKDQWDATDYVGIILAVPHRAYVEQLTALTEPLVGARRVFVDLRGALPLGHSTWRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI86</accession>
    <name>A0A1Q2CI86_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_14335</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the sigma-70 factor family. ECF subfamily.</text>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP45839">
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="96"/>
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        <location>
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            <end position="176"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="187" mass="20651" checksum="AC50E94142F75EB1" modified="2017-04-12" version="1">MAPDDRQTPVGLLATQLAAGDESALREAYHRWSRLIHTIARNSLGSAADADDVTQQVFIAAWNSRASLRASDEALPAWLIGICRMKVIDALRARSRGFRNEEAMMSEALDEPVVRNLDGVIDSVVVRDALAALGDPRAQILTMVYLEDKTHDDVARHLSIPLGTVKSHVRRGLERLRSVFEEVDSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI89</accession>
    <name>A0A1Q2CI89_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted arabinose efflux permease, MFS family</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">RPIT_14295</name>
        <name evidence="3" type="ORF">SAMN05428934_11241</name>
    </gene>
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ14981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45831">
        <property type="protein sequence ID" value="AQP45831"/>
        <property type="gene ID" value="RPIT_14295"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ14981">
        <property type="protein sequence ID" value="SDZ14981"/>
        <property type="gene ID" value="SAMN05428934_11241"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14295"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="314"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="343"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="410"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ14981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="437" mass="44985" checksum="AEDB2939488713F5" modified="2017-04-12" version="1">MTTSESVYTALVHRSSAADESIAEEDRSTVARNGLRIVGASALQASGDQATKASTVLPWLLHALGAPAALIGLLVPIRESGSMLPQAFLTPIVMRYRQRKWVVVVGHAVQAASVAVMTLIAAVGSGLWAGVGIVGALAVFSLGRCLTSIASKDVLGRTLPKGERGQVNGLATTASGIVAITLGLGLRLLGGQQLEATQLAWVLGGAAALWVLAAVLYAQVEEPDDDASADGESDGSWAALRLLRDDRDFRRFVTTRSFLLVSALAPPFIVSMSASSGADAVVGLGGFVVASGVASIIGGRLFGRMADRSSRRLMAFGAAASAAVVLLIVGIVALPGFSGETTVGTLVLVVGYFLLTLLHTGVRVGRKTYIVDMAEGDQRTLYVAVSNTAMGIILLVVGAISSAIALLGTVWALVFLAALGALGAVWGWRLPEVSQGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIA5</accession>
    <name>A0A1Q2CIA5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">O-Antigen ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_14050</name>
        <name evidence="5" type="ORF">SAMN05428934_11710</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
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        <property type="gene ID" value="RPIT_14050"/>
    </dbReference>
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        <property type="gene ID" value="SAMN05428934_11710"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="O-antigen_ligase-related"/>
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        <location>
            <begin position="64"/>
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            <end position="273"/>
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            <end position="296"/>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP45785.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDZ20864.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="326" mass="33980" checksum="CF87C114AF7D2B83" modified="2017-04-12" version="1">MKVHLSFIDRAGIVLLGLWGTWVVASAISHESAFADALPYLTAPTFGALGVAAGRLLQTRGIPRWFAASLLALSVYVLAGVTVLGRASSPLGYANANAALAVQLSAVAAITALSVRGQARSWAIWAAALFAVAVPWTLSRAGLVLLIAYLVAVAVATIGPAKRRPWVIPASALMVVAAGATVMHAARMSEWPPAYTQAFSSARRQLWSEALGLWAKHPVTGGGPGSFRAIGGLTLDSDTERVHMSVLQVGSELGIIGVILFATFVLLAFVQLVPAEPRSRLLGAAAVAALFIHTFVDHLLEFPAIPLAMGMVVGLASHSRSGVNRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
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    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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                <person name="Schumann P."/>
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            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
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            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP45842">
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        <property type="gene ID" value="RPIT_14350"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ15176"/>
        <property type="gene ID" value="SAMN05428934_11252"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="117"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
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            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="378" mass="40708" checksum="986F77B53AB4A484" modified="2017-04-12" version="1">MGNADGLTFTATRDEFHYRPGAEATAIYTVAYPVDGAEVVDHLLISTAAVGEPAVEVTTEHGRFSVWRHPADPRLPALAAACDPATVLSWLGQLPPHRDGIAELDISLLAYRPLRRAVLRLTADGRTWFVKVMPERKASILADRIDPVAAAGLTAPIALRPRPGVLVTAAVPGVSLAQRLVDWQFLGHALPEPADLAELLDQVPDAVTDLPRRESWADRLDFHSATAAHELPEHADRIASLAARIQTLLDSLPAGPVVPVHGDFYEANIFVSDQGLRVIDMDSCGPGHRVDDLACCLAHLAVLPSLSPESYPRIDEVLAHWLTDFDQRVNPASLRARVAAVLVSLISGAGPLAETWLELAEIWADSAVSAHGKLARRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIH4</accession>
    <name>A0A1Q2CIH4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cellulose synthase (UDP-forming)</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_14775</name>
        <name evidence="4" type="ORF">SAMN05428934_10965</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14775"/>
    <dbReference type="EnsemblBacteria" id="AQP45912">
        <property type="protein sequence ID" value="AQP45912"/>
        <property type="gene ID" value="RPIT_14775"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05817">
        <property type="protein sequence ID" value="SDZ05817"/>
        <property type="gene ID" value="SAMN05428934_10965"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14775"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="424"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="493"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="521"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="147"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ05817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="612" mass="68144" checksum="1156961ACD0CF6B4" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIH8</accession>
    <name>A0A1Q2CIH8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14875"/>
    <dbReference type="EnsemblBacteria" id="AQP45929">
        <property type="protein sequence ID" value="AQP45929"/>
        <property type="gene ID" value="RPIT_14875"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14875"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="3"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="416" mass="46139" checksum="0BB08C505D25A8E9" modified="2017-04-12" version="1">MASLLILGGGTAGTMAANLLRKHLPSEWTITVVDRDDDHHYQPGYLFVPFWMKPSRVSRNRWAQLSGGIEHIQAAVSRVVPDERRVNLADGRSLDYDWLIIASGSVPRHDLIPGLSDGPLWGTKIHDFYTLDGARRLAEALPDFEEGKILVHLAELPIKCPVAPLEFAFLLEDHFRKRGNRHKVDITYVTPLDGAFTKPVSAKAFGDLLEDRSIRLAADFTVSHVDNDTSRLVSYDGRELPFDLLVTIPPHTGAQFITDSGLGNDMGFVPVDKLTLRAKADDRIFVLGDASDIPTSKAGSVAHFATELFVDNFLAAIKGEPLPNEFDGHANCFLESGRGQALLLDFNYDTEPLPGEFPAPVVGPMKLLKRTRLNHLGKLAFEQIYWHMLLPGKRLPVPLKMSMAGKRQPDTAQKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIQ9</accession>
    <name>A0A1Q2CIQ9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Branched-chain amino acid ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_00320</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AzlC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00320"/>
    <dbReference type="EnsemblBacteria" id="AQP45935">
        <property type="protein sequence ID" value="AQP45935"/>
        <property type="gene ID" value="RPIT_00320"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00320"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011606">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34979">
        <property type="entry name" value="PTHR34979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03591">
        <property type="entry name" value="AzlC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="227" mass="23027" checksum="AFAD68F3F51EEF06" modified="2017-04-12" version="1">MASTVRALTPAQRRGLSVGLATGLYGISFGALAVTAGLSVWQASALSALMFTGGSQFAFIGVVAGGGALGSATAAASLLGVRNALYGVTANAMLRPHGWRKLLAAQVTIDESIATASGQDDPDEERRGFWTAGAAVFVLWNLFTLVGALAGNALGDPTVWGLDGAAVAAFLGLLWPRLSGRDPIAIAVVAAAVTLLAVPVVPAGLPIILAALVAALMTWAHVRSRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIR9</accession>
    <name>A0A1Q2CIR9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45945">
        <property type="protein sequence ID" value="AQP45945"/>
        <property type="gene ID" value="RPIT_00990"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00990"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="378" mass="42541" checksum="13684B0C0480C3A0" modified="2017-04-12" version="1">MHDAVSLLEAHQPDTDPAEFFSIVQKALMSSLRVLLRADDSSGIIGDAARRLLKLHPRAAAAANVKPAKLVDWMMKFQFEEEVSFFELDVVEYASALGESGIALYRRRLQEVAEPLGPEPAPREVWSSPHSRAWWTLHHNARRLAVLDRDVDEIIRTHARDHSVAKWLEDTSQALEEIGEIDLAIEWARRATDHDLGFQSSGAARRWISLVAAHRPEELVDAAHHVFSRWPTSGSALSLRDAAGDRWPEFRAAVQSRLRERPDEAVLFAIADESPERALKLAFELGITSEMTWDELARALGSVNPGEAILIHFMLAEGELREASAGNYREVARRLRFVRALAAGAGKEREVDEFIASLREAHRRRPRLQQEFTRAGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIT1</accession>
    <name>A0A1Q2CIT1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01430</name>
        <name evidence="3" type="ORF">SAMN05428934_10834</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45955">
        <property type="protein sequence ID" value="AQP45955"/>
        <property type="gene ID" value="RPIT_01430"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01581">
        <property type="protein sequence ID" value="SDZ01581"/>
        <property type="gene ID" value="SAMN05428934_10834"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01430"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ01581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="107" mass="10834" checksum="FAB3A1080EFECD4D" modified="2017-04-12" version="1">MVTIELAVGITLAMVVTVVLVGISLLGVAQAACAESSAQLARQAARGDEAQVSAATERAPSGSSIEWEWGSEGVGVVVSVDRELPLIGTVTLSADAWAAYEPGISPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIX5</accession>
    <name>A0A1Q2CIX5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_06425</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SCO1/2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06425"/>
    <dbReference type="EnsemblBacteria" id="AQP46054">
        <property type="protein sequence ID" value="AQP46054"/>
        <property type="gene ID" value="RPIT_06425"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06425"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd02968">
        <property type="entry name" value="SCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003782">
        <property type="entry name" value="SCO1/SenC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12151">
        <property type="entry name" value="PTHR12151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02630">
        <property type="entry name" value="SCO1-SenC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP46054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="158" mass="17018" checksum="8C732B46FC28AFB6" modified="2017-04-12" version="1">MPDVTLTDQDGNPYNLAEDPSTAAVVLFFGYTNCPDVCPGILADMATAKRRLPEDLVDDVTLIVVTTDPARDTPEALKEYLARVDDSFIGLTGSLDDIKPAALSLGIDIAEGKQLPSGGYEVDHGSYVLGFGEDRLLRVVWNEVPVSGMKDDYARLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ21</accession>
    <name>A0A1Q2CJ21_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_09150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP46102">
        <property type="protein sequence ID" value="AQP46102"/>
        <property type="gene ID" value="RPIT_09150"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09150"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP46102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="80" mass="8772" checksum="47D7C6C21F938CEB" modified="2017-04-12" version="1">MHRATVFSHLRRRNVPSRRPGLGIDEKAEAVRLARAAVSMRAIGRRMGVDRKAVREALAEAGLIVDCTNGARRSGLPNLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ28</accession>
    <name>A0A1Q2CJ28_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_12160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfur carrier protein TusA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12160"/>
    <dbReference type="EnsemblBacteria" id="AQP46148">
        <property type="protein sequence ID" value="AQP46148"/>
        <property type="gene ID" value="RPIT_12160"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12160"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001455">
        <property type="entry name" value="TusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036868">
        <property type="entry name" value="TusA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01206">
        <property type="entry name" value="TusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64307">
        <property type="entry name" value="SSF64307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF0033" evidence="2">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="67" mass="7210" checksum="F910707B70A8D539" modified="2017-04-12" version="1">MGQVCPFPLVEAKQAIKSLDVGDELIIDFDCTQGTDSIPHWAAAAGYPVTNFEQVGDATWTITVQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ92</accession>
    <name>A0A1Q2CJ92_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Capsular exopolysaccharide family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_13945</name>
        <name evidence="7" type="ORF">SAMN05428934_1119</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ11689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13945"/>
    <dbReference type="EnsemblBacteria" id="AQP46181">
        <property type="protein sequence ID" value="AQP46181"/>
        <property type="gene ID" value="RPIT_13945"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ11689">
        <property type="protein sequence ID" value="SDZ11689"/>
        <property type="gene ID" value="SAMN05428934_1119"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13945"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045226">
        <property type="term" value="P:extracellular polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005702">
        <property type="entry name" value="EPS_synthesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01007">
        <property type="entry name" value="eps_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="CbiA" evidence="5">
        <location>
            <begin position="258"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="451"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP46181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ11689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="486" mass="50815" checksum="4B8AC5BDEC8C0E87" modified="2017-04-12" version="1">MWGLLRRGWLVIVASLAVGLALAFALSLTQPVLYSATSAGYVVAGNSATVGDAFAGSTLAAEKAGTYLPLVQSRSVANRIAEELALPSTGPVVGNLEGSVDGVIFRIRATADSPELAASLADAAIRATSVEANALETLTITGESSGQTVVRIVPVELAQTPTTPVSPNYVRNLALGAALGLLLGLGIVVGRQSFDRRIRRAHEAEEVAETSSLGIVPAAAELAGESALVTGSSAAAEAIRQIRTNLRFVSVDNPAKSIVITSSNEGEGKSTLAANIAAMFADAGEPTVLIDADLRRPVQAERLGLDGAVGLSQVLAGTIKLSDAMQATDHKHLQVLPAGRIPPNPAEMVGSSRMRSLIEHLSKAHMVIIDAPPLLPVTDATLLSASADGAVVVVQSGTTRREQLEVAAHKLRQVDGNLLGVVLNKVAKKDLGEATFGYGYGSYTSKYYRTDEAQKPHRRERARRVTKLVETDDQAAELAEPRRPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJC2</accession>
    <name>A0A1Q2CJC2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ERCC4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12245"/>
    <dbReference type="EnsemblBacteria" id="AQP46150">
        <property type="protein sequence ID" value="AQP46150"/>
        <property type="gene ID" value="RPIT_12245"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12245"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006259">
        <property type="term" value="P:DNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006166">
        <property type="entry name" value="ERCC4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02732">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00891">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERCC4" evidence="1">
        <location>
            <begin position="125"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="274" mass="30877" checksum="D5175862FEBBFD81" modified="2017-04-12" version="1">MTLQIARNPEESSLPFLVRIPIGDGIVLRVKDTWPRTSKIYCHPHGLPWPEEPEIVEELSLRSCVKRGAAIDIEVDRTRESRSQFVFARARGREVIFWQSRRTSKTARPDVKLPTARASGLAELEILVDTRERYAWKFAAEQATTVKRALPVGDYGVEVDGELVAAVERKSLEDLVGSLLQGKLFEQQAALAELPHAVVLVEDRYSSVFKLTHVRPSVVADMLGEAQVRHPTVPVIFAETRPLAEQWAFRFFGAVLRERAMSEELDRRIGAGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CB88</accession>
    <name>A0A1Q2CB88_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Methylmalonyl-CoA carboxyltransferase 1.3S subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00055</name>
        <name evidence="4" type="ORF">SAMN05428934_10934</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00055"/>
    <dbReference type="EnsemblBacteria" id="AQP43413">
        <property type="protein sequence ID" value="AQP43413"/>
        <property type="gene ID" value="RPIT_00055"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05258">
        <property type="protein sequence ID" value="SDZ05258"/>
        <property type="gene ID" value="SAMN05428934_10934"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00055"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0092">Biotin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="2">
        <location>
            <begin position="45"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ05258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="119" mass="12350" checksum="CFD65D3385790D8C" modified="2017-04-12" version="1">MKLKVTVNQTEYEIDVEVEEEEPKGLGPIIIGVNAGSNQIPTKASVSAVSSNAVVAPLAGSVARILVSEGDEIESGQVLLILEAMKMETEITAPAAGRVARILVAPGEPVQGGQALIEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBA6</accession>
    <name>A0A1Q2CBA6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00070</name>
        <name evidence="3" type="ORF">SAMN05428934_10931</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00070"/>
    <dbReference type="EnsemblBacteria" id="AQP43414">
        <property type="protein sequence ID" value="AQP43414"/>
        <property type="gene ID" value="RPIT_00070"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05199">
        <property type="protein sequence ID" value="SDZ05199"/>
        <property type="gene ID" value="SAMN05428934_10931"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00070"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="PTHR11575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="SSF55816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="5_nucleotid_C" evidence="1">
        <location>
            <begin position="38"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ05199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="144" mass="15656" checksum="87617FBD2BB45B0F" modified="2017-04-12" version="1">MTSSFLEYSAKYFGTVAAGDTFDPEADTSVVYAGQKVPDYNSDILAGINYEIDLSQPVGSRIENLTMPDGSAVADDDQFVVALNNYRRSGGGNFPHVSTAPVVYNDLLEIRQLLIDWAVEKGTIDPADFYVPNWTLTVDGVPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBJ3</accession>
    <name>A0A1Q2CBJ3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH araC/xylS-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00500"/>
    <dbReference type="EnsemblBacteria" id="AQP43483">
        <property type="protein sequence ID" value="AQP43483"/>
        <property type="gene ID" value="RPIT_00500"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00500"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="20"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="289" mass="31761" checksum="1CA7C315F4F99B0E" modified="2017-04-12" version="1">MQTRTAHASGEQATPRPELDRLLGTVRADDVAPPTLEEMAASAHFSRFHLSRLLREHLGFPLRDFLAALRVERGIEALVAGHDVIRSQVEAGHESASSFSRSFARHTGMAPSRYRDQLRFLAAYLIRHMDSTDPLVAVHRNFPEVSHPQQVQLRISVDGAQAGSALFVALNSSLILQGAPNLGVALLGTRGYTVSEIPDGTYYAMVVEVPRSAGMRAYFQMDRNRRQLRREPITFPLSEPTEIVLTLRDLVPTDPPITPNLPKLFFEGALSSVTVEASNSGQESVGGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBK0</accession>
    <name>A0A1Q2CBK0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00490</name>
        <name evidence="2" type="ORF">SAMN05428934_10551</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY84792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43481">
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        <property type="gene ID" value="RPIT_00490"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY84792">
        <property type="protein sequence ID" value="SDY84792"/>
        <property type="gene ID" value="SAMN05428934_10551"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00490"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY84792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="198" mass="21189" checksum="293E58A0F5043DFA" modified="2017-04-12" version="1">MLISVEEGVLDEYLVVATPQEYDGSPGVNTFRMDYAPRSVHPDRLALAAYLLFRPWASGPLQLPSPVSPALAEAIAALHAVCSVQPGPVDLTPRTGPPGRRPLRLAWRTDHSSEPPPGGMTVNLLRSDEASGALRTAQSVWLPSNAFMLAETEARELDVALAIGCLLAGDLDVRELHLPVAVPEPLSRLLHRAGLSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBT9</accession>
    <name>A0A1Q2CBT9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01025</name>
        <name evidence="3" type="ORF">SAMN05428934_105156</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01025"/>
    <dbReference type="EnsemblBacteria" id="AQP43576">
        <property type="protein sequence ID" value="AQP43576"/>
        <property type="gene ID" value="RPIT_01025"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87595">
        <property type="protein sequence ID" value="SDY87595"/>
        <property type="gene ID" value="SAMN05428934_105156"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01025"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029471">
        <property type="entry name" value="HNH_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14279">
        <property type="entry name" value="HNH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH_5" evidence="1">
        <location>
            <begin position="41"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY87595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="117" mass="13245" checksum="C60514C3B2A65994" modified="2017-04-12" version="1">MVAARTMKQRAAKRRQRRIRGRIQDLSGEQWADLQGLWGGCAYCGAAGVPVQKDCVLPVSRGGRYTLENVVPACRSCNASKCNSEVTGWMRRKRLDEQNFLIRHLQIRAELVSRLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBX6</accession>
    <name>A0A1Q2CBX6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Exodeoxyribonuclease III</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Exodeoxyribonuclease-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_00850</name>
        <name evidence="5" type="ORF">SAMN05428934_105123</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00850"/>
    <dbReference type="EnsemblBacteria" id="AQP43545">
        <property type="protein sequence ID" value="AQP43545"/>
        <property type="gene ID" value="RPIT_00850"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86688">
        <property type="protein sequence ID" value="SDY86688"/>
        <property type="gene ID" value="SAMN05428934_105123"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00850"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008853">
        <property type="term" value="F:exodeoxyribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09086">
        <property type="entry name" value="ExoIII-like_AP-endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020847">
        <property type="entry name" value="AP_endonuclease_F1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037493">
        <property type="entry name" value="ExoIII-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43250">
        <property type="entry name" value="PTHR43250"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00633">
        <property type="entry name" value="xth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00726">
        <property type="entry name" value="AP_NUCLEASE_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="3">
        <location>
            <begin position="4"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="246"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY86688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="286" mass="31264" checksum="9B118858694DC63C" modified="2017-04-12" version="1">MRIATWNVNSAKQRMPRLLPWLAERQPDVVCLQETKLTDAGFADLFDGPLAELGYEAAHHGQGGFNGVALLSRVGLADVERNFAGQPDYRGATEARAISATCAGVRIRSLYVPNGREVSSDHYDYKLHWLDALADAVAQGPSDVALCGDMNVAPADADVFDPGAYIGHTHVTAPERERLSAFGLVDVVRARWPEHDRLFSYWDYRAGMFHQDLGMRIDLVLASRPVADRVAAAWVDRAARKGKLPSDHAPVIVDLDEAPDGDIGPVVPPPSNPKRGGRTRLPQSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBZ4</accession>
    <name>A0A1Q2CBZ4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BIG2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01315</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01315"/>
    <dbReference type="EnsemblBacteria" id="AQP43622">
        <property type="protein sequence ID" value="AQP43622"/>
        <property type="gene ID" value="RPIT_01315"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01315"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003343">
        <property type="entry name" value="Big_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011081">
        <property type="entry name" value="Big_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02368">
        <property type="entry name" value="Big_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07532">
        <property type="entry name" value="Big_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00635">
        <property type="entry name" value="BID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012298034" description="BIG2 domain-containing protein" evidence="1">
        <location>
            <begin position="43"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="domain" description="BIG2" evidence="2">
        <location>
            <begin position="544"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="661" mass="70571" checksum="FFD6300F9FBB1DB5" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC01</accession>
    <name>A0A1Q2CC01_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Endonuclease III</fullName>
            <ecNumber evidence="10">4.2.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">DNA-(apurinic or apyrimidinic site) lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">nth</name>
        <name evidence="12" type="ORF">RPIT_01380</name>
        <name evidence="13" type="ORF">SAMN05428934_10823</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="10">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the Nth/MutY family.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="10"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01380"/>
    <dbReference type="EnsemblBacteria" id="AQP43631">
        <property type="protein sequence ID" value="AQP43631"/>
        <property type="gene ID" value="RPIT_01380"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01342">
        <property type="protein sequence ID" value="SDZ01342"/>
        <property type="gene ID" value="SAMN05428934_10823"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01380"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019104">
        <property type="term" value="F:DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00942">
        <property type="entry name" value="Nth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004036">
        <property type="entry name" value="Endonuclease-III-like_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003651">
        <property type="entry name" value="Endonuclease3_FeS-loop_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004035">
        <property type="entry name" value="Endouclease-III_FeS-bd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005759">
        <property type="entry name" value="Nth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10576">
        <property type="entry name" value="EndIII_4Fe-2S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ENDONUCLEASE_III_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0408">Iron</keyword>
    <keyword evidence="7 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="11">
        <location>
            <begin position="36"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP43631.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDZ01342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="223" mass="24192" checksum="E3E57BDD89A5A879" modified="2017-04-12" version="1">MSSAEAIHEGLAAAYPDARCELDFRSPFELLVATVLSAQSTDRRVNSVTPALFARYPTPLALAEAEQAAVEELIGPVGFYRTKATAIIGLSRRIVDDFDGEVPANLDDLVTLPGVGRKTANVVLGNAFDVPGLTPDTHFIRLANRFGWVDSTKPDDVERAVAALFPPEDWVMVSHRLIWHGRRCCHARRPACGACPVRDLCPSSHLGEQDPAKAAALIREPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC46</accession>
    <name>A0A1Q2CC46_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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    </dbReference>
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    </dbReference>
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            <begin position="1"/>
            <end position="25"/>
        </location>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="AQP43625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="110" mass="10544" checksum="DB153BCF98FBB34F" modified="2017-04-12" version="1">MGCGTGLSEPVGANSPEGSTVEGSTVSLGAGTALVDGAAALEGAGSTGALDGAATLAGGVGVTSGPGLQAATSARTGRTAARVTVRTLGEYQPSTDTPVINIHDISWIWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC54</accession>
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    </protein>
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    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
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        <lineage>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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    </dbReference>
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        <property type="component" value="Chromosome"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="CpaE_hom_Actino"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="384" mass="38995" checksum="9BE2E3EDD6ECB74F" modified="2017-04-12" version="1">MRSSLQIVVGPQPSRDRVRAGARLRRDVIHSPEEDRQIRGLRTANAGMDDINARVLLCARDPAVIEAVEVIAAALEVPLCVAGDSSTVRSGWKSSSLRLVSVEVASRWSSVPPGRAFLVGTSVAELARCSAELSLPVLPLPDRSGRLADALVSAARPAVRGALVLGLVGASGGLGVSTVTAGLALIAAAGGRAAAAVDLARCSGGLDLVFGAETAAGVRWSDLSGAQGELGDVLGSLPTVDGVGVLASSRDDPQQPSSGAVAAVATSLTRAVQLVVIDSGNEAPPVECDHVLLMVGGDVRSVAAARMLASQTGLSPSGLIVRRGPGRALAPGVVSRALGVPVKGVVGQHNSLPKLAELGLPPTSAPARRYRKELTVLLKGITDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC76</accession>
    <name>A0A1Q2CC76_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01855</name>
        <name evidence="3" type="ORF">SAMN05428934_108119</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
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    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ03225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43706">
        <property type="protein sequence ID" value="AQP43706"/>
        <property type="gene ID" value="RPIT_01855"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ03225">
        <property type="protein sequence ID" value="SDZ03225"/>
        <property type="gene ID" value="SAMN05428934_108119"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01855"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ03225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="134" mass="14657" checksum="1FF9D28B7F218D1E" modified="2017-04-12" version="1">MLAHTRRADVWHVAALWVATAATIFGVVVLLLWPLEIVLPVTRGARVISSLAFTVLIGGLAGVGWYSHIRRKLVQWNYLAIGLMLLIVTWGLTDGALRELAAGNWVWMGVSAGLALGGMVVSDSFLWRGLRRPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC93</accession>
    <name>A0A1Q2CC93_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Glyoxalase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01660</name>
        <name evidence="3" type="ORF">SAMN05428934_10881</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01660"/>
    <dbReference type="EnsemblBacteria" id="AQP43675">
        <property type="protein sequence ID" value="AQP43675"/>
        <property type="gene ID" value="RPIT_01660"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02451">
        <property type="protein sequence ID" value="SDZ02451"/>
        <property type="gene ID" value="SAMN05428934_10881"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01660"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025870">
        <property type="entry name" value="Glyoxalase-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13468">
        <property type="entry name" value="Glyoxalase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyoxalase-like_dom" evidence="1">
        <location>
            <begin position="4"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ02451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="211" mass="23190" checksum="A321602E3E9D6A95" modified="2017-04-12" version="1">MHVDHLIFATGPDGLKSEAARLAEALGTDYKDGGFHPRFGTRNHIIPLAEGRYIEVVEVLDHPAADKAAFGQAVRARSEMGGGWLGWVVSVPNIAPYEQRLERSAVQGSRHFPDGRKLEWVQIGIRGLIADPQLPYFLEWKSDESLRPSALHGDVKLTSLQISGSAERLSEWLDLEIGEEIDGIILELVSPRGMPGINHVTFETPNGPVTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCE1</accession>
    <name>A0A1Q2CCE1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Homeodomain-like domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_02315</name>
        <name evidence="2" type="ORF">SAMN05428934_10163</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY24175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02315"/>
    <dbReference type="EnsemblBacteria" id="AQP43793">
        <property type="protein sequence ID" value="AQP43793"/>
        <property type="gene ID" value="RPIT_02315"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY24175">
        <property type="protein sequence ID" value="SDY24175"/>
        <property type="gene ID" value="SAMN05428934_10163"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02315"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY24175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="157" mass="17056" checksum="19D4EDF0707A866F" modified="2017-04-12" version="1">MANKPAPALPLREGDQAILEKVLRTSSTTAGAAQRARIVLLASQGTTNALIAELAGVSRPTVNLWRGRYLEHGMAGLVDVQRPGRPKVVDDAEIITATLTPPPKRLGVTHWSSRLLAPRLGVHHSTITKAWKKYGVRPWKAETFKFSTEPRTGGQGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCH7</accession>
    <name>A0A1Q2CCH7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Amidophosphoribosyltransferase</fullName>
            <shortName evidence="5">ATase</shortName>
            <ecNumber evidence="5">2.4.2.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Glutamine phosphoribosylpyrophosphate amidotransferase</fullName>
            <shortName evidence="5">GPATase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">purF</name>
        <name evidence="11" type="ORF">RPIT_02380</name>
        <name evidence="12" type="ORF">SAMN05428934_10174</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = 5-phospho-alpha-D-ribose 1-diphosphate + H2O + L-glutamine</text>
            <dbReference type="Rhea" id="RHEA:14905"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="EC" id="2.4.2.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5 8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5 9">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.14" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY24511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02380"/>
    <dbReference type="EnsemblBacteria" id="AQP43806">
        <property type="protein sequence ID" value="AQP43806"/>
        <property type="gene ID" value="RPIT_02380"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY24511">
        <property type="protein sequence ID" value="SDY24511"/>
        <property type="gene ID" value="SAMN05428934_10174"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02380"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00124"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004044">
        <property type="term" value="F:amidophosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00715">
        <property type="entry name" value="GPATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01931">
        <property type="entry name" value="PurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005854">
        <property type="entry name" value="PurF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035584">
        <property type="entry name" value="PurF_N"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000485">
        <property type="entry name" value="Amd_phspho_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01134">
        <property type="entry name" value="purF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5 6 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5 6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="10">
        <location>
            <begin position="17"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5 7">
        <location>
            <position position="17"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 9">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="368"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 9">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 9">
        <location>
            <position position="456"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 9">
        <location>
            <position position="459"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP43806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY24511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="482" mass="52163" checksum="988448EE06519A5D" modified="2017-04-12" version="1">MLATDELKDLEGPKEECGVFGVWAPDEDVAQLTFFGLFALQHRGQESAGMAVSNGSRIMVYKDMGLVAQVFDEATLKSLPGRLAIGHTRYSTTGASVWHNAQPTFRAVAGGGLALAHNGNLTNTHELEAWLAELAPSAEVPAKKTMDSTNDTSLVTALMSSFGEEPVESIAMKVLPRLKGAFCLTFMTERTLFAARDPQGFRPLVIGRLSHGWVVASETAALDIVGASFVREVEPGEFIAIDERGLRSQRFADSRPKGCIFEYVYLARPDTTIAGRGVHTTRVRIGEILARESPADADLVIPTPSSGIPSAIGYARGSGLPYGEGLVKNNYVGRTFIEPTQTIRQLGIRLKLNPLREVIDGKRLVVVDDSIVRGNTQRALVRMLREAGAKEVHVRISSPPVQWPCFYGIDFSTRAELIAPGLTVEEICRSIGADSLGYISLDGLTEATQLPAENLCRACFDGDYPVAIPPAHAELLNLEVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCI2</accession>
    <name>A0A1Q2CCI2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cation diffusion facilitator family transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Cation-efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_02545</name>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="AQP43833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP43833">
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    </dbReference>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <sequence length="318" mass="33395" checksum="5E22004C646D3DE7" modified="2017-04-12" version="1">MSTSPRRALALLLVPLVLLLSSCIRMTADYDIVSENEVTLVADFGIQNSAAAQMGSEVPDLCEQEGFDDVQGATAEPYAEEGDGGYTGCRISGTARTSDLSGDGTTIELADGVWTFAMEGTPGEEEMSAEMFSDFRVSVTFPGKVLSHNGTSTVEGTTVTWSTAADMFTADGLLATAEDGAGGVDWLWIALGALVIAGIAAAVVVATRNRRRHEPEPTFQDGSTPYPYPHPPGPGQQYAPPPPGQAYPPPTHVPPMTPTPQQPEADQPFPARPPAQDPWAQAAPESQPTPPRAPADQPPPRPAAGPGPDFRDNPPPTP</sequence>
</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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    </evidence>
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            <dbReference type="Proteomes" id="UP000199635"/>
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</entry>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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            <dbReference type="PubMed" id="26869509"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03160"/>
    <dbReference type="EnsemblBacteria" id="AQP43938">
        <property type="protein sequence ID" value="AQP43938"/>
        <property type="gene ID" value="RPIT_03160"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29320">
        <property type="protein sequence ID" value="SDY29320"/>
        <property type="gene ID" value="SAMN05428934_101233"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03160"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01302_B">
        <property type="entry name" value="Ribosomal_S8_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_S8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_S8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="PTHR11758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="SSF56047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY29320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="134" mass="14655" checksum="CA42A4CE0F40B0E0" modified="2017-04-12" version="1">MTMTDPIADMLTRLRNANQAYHEETTMPSSKIKVGIAEILKAEGYISNYELTEVEGQVGQVLKLTLKYGDSRERSIIGIRRISKPGLRVYAKANELPKVLNGMGIAIISTSQGLLTDKAAKAKSVGGEVLAYVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCW8</accession>
    <name>A0A1Q2CCW8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Monosaccharide ABC transporter membrane protein, CUT2 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_03290</name>
        <name evidence="8" type="ORF">SAMN05428934_101259</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03290"/>
    <dbReference type="EnsemblBacteria" id="AQP43959">
        <property type="protein sequence ID" value="AQP43959"/>
        <property type="gene ID" value="RPIT_03290"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30085">
        <property type="protein sequence ID" value="SDY30085"/>
        <property type="gene ID" value="SAMN05428934_101259"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03290"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY30085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="331" mass="34400" checksum="8AB08C2C25D8E54B" modified="2017-04-12" version="1">MSDPAVDSKPKFDTTGFIKTYAILLILIAFMVILAIITQGTFLQPRNLINVVVQVAPIGIIALGMMFAIITKGIDLSVGSTVALVAVVSASLAQVQSDSMMFPGLPPMPVFVAVIAGLLVGAAVGAVVGSLVAYFHIPPFVATLGMMTAARGLANIYTGGRPVSNLADGFNWMGQGDVFGIPVPMIIFIIIAAIIWVVLNRTRFGRHVYAIGGNDQAARVSGISIGRVQFLIYTLIGLLAGLAGMILAARIGSGQPTLGVMLELDAITAAVIGGTSFNGGVGTVWGVVVGALIIGVINNGLDLMNVSPFMQMVVKGAIIVIAIIIDERKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCZ2</accession>
    <name>A0A1Q2CCZ2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF2510 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_03495</name>
        <name evidence="5" type="ORF">SAMN05428934_101299</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY31321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43993">
        <property type="protein sequence ID" value="AQP43993"/>
        <property type="gene ID" value="RPIT_03495"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY31321">
        <property type="protein sequence ID" value="SDY31321"/>
        <property type="gene ID" value="SAMN05428934_101299"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03495"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018929">
        <property type="entry name" value="DUF2510"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10708">
        <property type="entry name" value="DUF2510"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2510" evidence="3">
        <location>
            <begin position="4"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY31321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="282" mass="31042" checksum="171720FE3654E2AD" modified="2017-04-12" version="1">MAEPGWYADPTAPSGRRYWDGARWADLDTRTSRRPNAWLWFVLALVVVGALVAALVFLPNSSSPFGATPVDTRTARPTGSQWNELVPSETPSPTAIESGFGAPIDCPISDEFPRSEVRGGEISGGGLTIQEPPGREWRESPAWIDWMYDYNSVIRDIAPGWISNVGVGYIKVSDGFAQNPATMAEQFVTCMASSGMFLGFTKREILINEEYVVSDRIGWRLQSNVYVGNQIHNGIEGDVVDIIVVPTDDEDRFSVYVSCATIGHEENLEQVAVSLETLRYDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD29</accession>
    <name>A0A1Q2CD29_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome C oxidase assembly protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Putative copper resistance protein D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_03725</name>
        <name evidence="9" type="ORF">SAMN05428934_101347</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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        </citation>
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            <strain evidence="8">RP1T</strain>
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        <subcellularLocation>
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    <sequence length="320" mass="33002" checksum="B6F34523AF26962E" modified="2017-04-12" version="1">MIRRALAGACIAGLLLTACAEGGDESSVSISAVTIMSHPSLDAVYDGIREGLADAGYVDGDNLSLEFQNPQGDQSTLTSIANTYAASDADLFVALATPPAQALAQVIQDRPIVFASVTDPVAAGLVDSFEAPGGNVTGTSDQLPTDEQLRVILEIDPTVETVGIVYSSAEVNAQVQAEAAVVAGNELGITVETATVANSSEVQQAAESLDVDAYFILVDNTVVSAMATMVQIAEDKQSLLVTSDPDSVEIGAAAALSTDYRSQGLQTAAMIVRILEGADPAETPVEVQESLEFVVNPSAAERMGVTIPDEVLAKADRTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD94</accession>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
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    <reference evidence="8 10" key="2">
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="7" key="3">
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                <person name="Peterson S.W."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
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        <property type="entry name" value="HAD-like_sf"/>
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        <property type="entry name" value="HAD_sf"/>
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        <property type="entry name" value="P_typ_ATPase"/>
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        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
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        <property type="entry name" value="HATPASE"/>
    </dbReference>
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        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
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        <property type="entry name" value="ATPASE_E1_E2"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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        <location>
            <begin position="712"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="752"/>
            <end position="773"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY33238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="792" mass="84050" checksum="67C2C675799BC2E8" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDE3</accession>
    <name>A0A1Q2CDE3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitrogen fixation protein NifU</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">SUF system NifU family Fe-S cluster assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04365</name>
        <name evidence="3" type="ORF">SAMN05428934_101478</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY36349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04365"/>
    <dbReference type="EnsemblBacteria" id="AQP44142">
        <property type="protein sequence ID" value="AQP44142"/>
        <property type="gene ID" value="RPIT_04365"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY36349">
        <property type="protein sequence ID" value="SDY36349"/>
        <property type="gene ID" value="SAMN05428934_101478"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04365"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06664">
        <property type="entry name" value="IscU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002871">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10093">
        <property type="entry name" value="PTHR10093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01592">
        <property type="entry name" value="NifU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NifU_N" evidence="1">
        <location>
            <begin position="7"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY36349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="147" mass="16236" checksum="B55D6493056592A9" modified="2017-04-12" version="1">MNIDELYQTIILDHYREKHHSGLRDGYDVEVHHVNPSCGDELTLRVHLDGGTVRDISYHAEGCSISQASTSVMTDLLIGGDTASALDLHDKFLEMMQSQGRIEPDEDTFEDAIAFAGVSKFPARVKCALLGWSAMRDATLQATAKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDP5</accession>
    <name>A0A1Q2CDP5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04905"/>
    <dbReference type="EnsemblBacteria" id="AQP44234">
        <property type="protein sequence ID" value="AQP44234"/>
        <property type="gene ID" value="RPIT_04905"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04905"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021447">
        <property type="entry name" value="DUF3097"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11296">
        <property type="entry name" value="DUF3097"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="278" mass="30750" checksum="CB6986A3DE9294E3" modified="2017-04-12" version="1">MDRYSRDVLAPGWQKAHLKKTRDVAVELDLVVEFDDFCGAVVGWENGLVILEDRKLKRRSAPFGPGFLLEGQPVALRPPLRGGPSRPTYTASGSRASAQPEKAKVALPSRIYVEGRHDAELIEKVWGEDLRHVGVVVEFLGGIDDLPAIVAEFAPAPGRRLGVLVDHLVPGSKESRIAAQVYKAGYRETVLVEGHEFIDIWQAVKPARVGRKAWPEVPRDVDFKKGTLAALGLPHADQADVARGWQAILARVQSWRDLEPQLNTKVETLIDFVTQDHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDS4</accession>
    <name>A0A1Q2CDS4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_04950</name>
        <name evidence="2" type="ORF">SAMN05428934_101596</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY39281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44241">
        <property type="protein sequence ID" value="AQP44241"/>
        <property type="gene ID" value="RPIT_04950"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY39281">
        <property type="protein sequence ID" value="SDY39281"/>
        <property type="gene ID" value="SAMN05428934_101596"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04950"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY39281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="171" mass="19413" checksum="6AAA5A81EBA86BB1" modified="2017-04-12" version="1">MTYRYGLKWNVRRGHPVEEIDEVTARDRFQVGPQFSVSRVTQGRTVPDYTLSMQPGGAQLRVLKYDPEGSIAEIFDYSERDGRGGLFMHGYATYVYPDDEIGPRTLSQSVAHKSWVFREDGTATCREVVKPVPDARISEYRGLDVSGHWRSRPEFGDWDSFGDHPEPGGIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDU8</accession>
    <name>A0A1Q2CDU8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsT</name>
        <name evidence="9" type="ORF">RPIT_04860</name>
        <name evidence="10" type="ORF">SAMN05428934_101580</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Binds directly to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bS20 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY38865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04860"/>
    <dbReference type="EnsemblBacteria" id="AQP44225">
        <property type="protein sequence ID" value="AQP44225"/>
        <property type="gene ID" value="RPIT_04860"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY38865">
        <property type="protein sequence ID" value="SDY38865"/>
        <property type="gene ID" value="SAMN05428934_101580"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04860"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00500">
        <property type="entry name" value="Ribosomal_S20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002583">
        <property type="entry name" value="Ribosomal_S20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036510">
        <property type="entry name" value="Ribosomal_S20_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33398">
        <property type="entry name" value="PTHR33398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01649">
        <property type="entry name" value="Ribosomal_S20p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46992">
        <property type="entry name" value="SSF46992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00029">
        <property type="entry name" value="S20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY38865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="86" mass="9096" checksum="42D7E83B3DAC83D4" modified="2017-04-12" version="1">MANIKSQQKRNKTNEKARLRNKAVKSALRTHVRNARAAVAEGDPAKAAALAAVANRSLDKAVSKGVIHKNQAANRKSAISQAVAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDW2</accession>
    <name>A0A1Q2CDW2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Pyruvate dehydrogenase E1 component</fullName>
            <ecNumber evidence="2 8">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_05250</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>(R)-N(6)-lipoyl-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + H(+) + pyruvate = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10480"/>
            <dbReference type="Rhea" id="RHEA-COMP:10481"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="2 8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05250"/>
    <dbReference type="EnsemblBacteria" id="AQP44293">
        <property type="protein sequence ID" value="AQP44293"/>
        <property type="gene ID" value="RPIT_05250"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05250"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02017">
        <property type="entry name" value="TPP_E1_EcPDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035807">
        <property type="entry name" value="PDC_E1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004660">
        <property type="entry name" value="PDH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041621">
        <property type="entry name" value="PDH_E1_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43825:SF3">
        <property type="entry name" value="PTHR43825:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17831">
        <property type="entry name" value="PDH_E1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000156">
        <property type="entry name" value="Pyruvate_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00759">
        <property type="entry name" value="aceE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="10">
        <location>
            <begin position="159"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="PDH_E1_M" evidence="11">
        <location>
            <begin position="508"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000156-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP44293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="929" mass="102510" checksum="722BFEAF57B412A1" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDY4</accession>
    <name>A0A1Q2CDY4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbonic anhydrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05490</name>
        <name evidence="4" type="ORF">SAMN05428934_10345</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05490"/>
    <dbReference type="EnsemblBacteria" id="AQP44334">
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    <dbReference type="EnsemblBacteria" id="SDY66304">
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        <property type="gene ID" value="SAMN05428934_10345"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05490"/>
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        <property type="component" value="Chromosome"/>
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        <property type="entry name" value="Carbonic_anhydrase_sf"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY66304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="163" mass="17416" checksum="A0913D80B4F7AD0E" modified="2017-04-12" version="1">MSFDDLLQANASYAENFEDGYFDGIAKAGVAIVTCMDSRIEPLGMVGLRIGDAKILRSPGGRVSTSVLNGCVLSVQLLQVDRIMIIPHTRCAMASGTDDDLRKVISAKTGTDASWLSFGASPDQAGRLRTDVDMVSNHPLIKGHAEVGGFLYDVDTGLLKQII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDY5</accession>
    <name>A0A1Q2CDY5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_05380</name>
        <name evidence="2" type="ORF">SAMN05428934_10323</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY65645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44313">
        <property type="protein sequence ID" value="AQP44313"/>
        <property type="gene ID" value="RPIT_05380"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY65645">
        <property type="protein sequence ID" value="SDY65645"/>
        <property type="gene ID" value="SAMN05428934_10323"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05380"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY65645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="156" mass="16854" checksum="4DBC1C552D0699BC" modified="2017-04-12" version="1">MRRRLVFIPIAPDEMGALAGRSELVDRTAYSVTPELLEELGYGAEETEDAEYAALILASVAGLAAHGTRLIVVAEVDPASVEPGDDPTNGQVWLRSCPPSAITAWFADEPGVDVADAAAISKGMTIDQAWDQPAVQDLLHNHDLLWNDVVEYRREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE01</accession>
    <name>A0A1Q2CE01_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Phosphatidate phosphatase APP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05500</name>
        <name evidence="4" type="ORF">SAMN05428934_10347</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY66356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05500"/>
    <dbReference type="EnsemblBacteria" id="AQP44336">
        <property type="protein sequence ID" value="AQP44336"/>
        <property type="gene ID" value="RPIT_05500"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY66356">
        <property type="protein sequence ID" value="SDY66356"/>
        <property type="gene ID" value="SAMN05428934_10347"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05500"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019236">
        <property type="entry name" value="APP1_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09949">
        <property type="entry name" value="DUF2183"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2183" evidence="2">
        <location>
            <begin position="200"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY66356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="346" mass="38550" checksum="EF174A44FB3ACE9E" modified="2017-04-12" version="1">MASRPFFAARLEDRFSRLVGRTLERRGWEESIISYTGYGTSEQLRILARVVLRPSDDLGIVQAASALIYRRGWRNFINASKVSPRVTVVIDDVRIPIEADRNGYVDVRVRNPGLTPGWHNVTLEGEGGASAVAPVQVIADDVDFGIVSDIDDTIISTWLPRPLIAAWNSFVLTEQARQAVPGMARLYQKLLAEHPGAPIIFVSTGAWNTYPMIQRFIARHGIPNGAMLFTDWGPTNTGWFRSGQDHKRRCLHELARDLPGIRWVLVGDDGQHDPELYAEFASLRPEHVRARAIRQLTPGEHALAHGLPMEVPAHEAEWAPDMAPEVRAPDGDGLGDKLRELLTPQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE02</accession>
    <name>A0A1Q2CE02_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Cell division ATP-binding protein FtsE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ftsE</name>
        <name evidence="8" type="ORF">RPIT_05295</name>
        <name evidence="9" type="ORF">SAMN05428934_1036</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Part of the ABC transporter FtsEX involved in cellular division.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer. Forms a membrane-associated complex with FtsX.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY65157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05295"/>
    <dbReference type="EnsemblBacteria" id="AQP44300">
        <property type="protein sequence ID" value="AQP44300"/>
        <property type="gene ID" value="RPIT_05295"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY65157">
        <property type="protein sequence ID" value="SDY65157"/>
        <property type="gene ID" value="SAMN05428934_1036"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05295"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005286">
        <property type="entry name" value="Cell_div_FtsE_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02673">
        <property type="entry name" value="FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6 8" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="2"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY65157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="228" mass="25588" checksum="497CF03CAAC5192C" modified="2017-04-12" version="1">MITFEDVTKFYPGQERAALRNVNLEIGRGEFVFLVGQSGSGKSTFLRLILREYRPTRGTLYVAGKNLTTMNQWKVPALRRQIGTVFQDFRLLPGKSVYENVAFALQVIGRPAKEIRRIVPDTLDLVGLTGKENRPCEELSGGEQQRVAIARAFVNRPKILIADEPTGNLDPETSVGIMKLLDRINRADTTVIMATHDSSIVDQMRRRVLELREGELVRDQAKGIYGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE28</accession>
    <name>A0A1Q2CE28_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Potassium transporter TrkA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05595"/>
    <dbReference type="EnsemblBacteria" id="AQP44351">
        <property type="protein sequence ID" value="AQP44351"/>
        <property type="gene ID" value="RPIT_05595"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05595"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="1">
        <location>
            <begin position="2"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="2">
        <location>
            <begin position="136"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="220" mass="24192" checksum="A7683AA3842CE839" modified="2017-04-12" version="1">MHIVIMGCGRVGAMLATGLEKLGHSVAIIDVDKDSFRRLGPDFEGLTVTGVGFDREVLENAQIRRADAFAAVSSGDNSNILAARVVREIYHVDNVVARIYDQGRAAVYERLGIPTVATVKWTVSQVLRRLLPEGSEPVWRDPTGTARLLQIHVHNGWVGRKISELQEAANSPIPFVRRVGRGIVPDRDTVFQDGDLIYVACHTDRTDALETLFANPPART</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE39</accession>
    <name>A0A1Q2CE39_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Thymidine kinase</fullName>
            <ecNumber evidence="2 9">2.7.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_05520</name>
        <name evidence="13" type="ORF">SAMN05428934_10351</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + thymidine = ADP + dTMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19129"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17748"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the thymidine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.21" evidence="2 9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY66466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05520"/>
    <dbReference type="EnsemblBacteria" id="AQP44340">
        <property type="protein sequence ID" value="AQP44340"/>
        <property type="gene ID" value="RPIT_05520"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY66466">
        <property type="protein sequence ID" value="SDY66466"/>
        <property type="gene ID" value="SAMN05428934_10351"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05520"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004797">
        <property type="term" value="F:thymidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001267">
        <property type="entry name" value="Thymidine_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11441">
        <property type="entry name" value="PTHR11441"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00265">
        <property type="entry name" value="TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035805">
        <property type="entry name" value="TK_cell"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="6 9 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR035805-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP44340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY66466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="216" mass="23961" checksum="796074335D5F3575" modified="2017-04-12" version="1">MAELVFHTGPMDCGKSTMALQLDYIQSAHGRKGRVFTSQDRSGTGVITSRLGLTASALEVEPEFDFWRYIIGELTSGQRVDYIVCDEAQFYSVEQVDQLARIADELQLDVYAFGILADFRTRLFPGSQRLIELADRVETLPLGPLCWCGARGTHNARTVDGLMVTEGSQVVVGDTASGGEVRYEVLCRAHHRRRMTATRAKATLSPDPLPFDPENF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEA2</accession>
    <name>A0A1Q2CEA2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Four-helix bundle copper-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_06040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06040"/>
    <dbReference type="EnsemblBacteria" id="AQP44427">
        <property type="protein sequence ID" value="AQP44427"/>
        <property type="gene ID" value="RPIT_06040"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06040"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005560">
        <property type="entry name" value="DUF326"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03860">
        <property type="entry name" value="DUF326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="135" mass="14512" checksum="7979B7DAF77E1BB7" modified="2017-04-12" version="1">MTMSTAARMLETYPGEPLLSASQLAECLDACFDCAQCCTACADACLAEEMVADLRACIRFNQDCADVCAMTGALLTRQTQPNVQLLRQALELCAAACAACAEECEKHAGHHEHCKVCAESCRRCEKACRDLLAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEA5</accession>
    <name>A0A1Q2CEA5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Elongation factor P</fullName>
            <shortName evidence="7">EF-P</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">efp</name>
        <name evidence="11" type="ORF">RPIT_06195</name>
        <name evidence="12" type="ORF">SAMN05428934_103184</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7 8">Belongs to the elongation factor P family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY69823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06195"/>
    <dbReference type="EnsemblBacteria" id="AQP44454">
        <property type="protein sequence ID" value="AQP44454"/>
        <property type="gene ID" value="RPIT_06195"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY69823">
        <property type="protein sequence ID" value="SDY69823"/>
        <property type="gene ID" value="SAMN05428934_103184"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06195"/>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04470">
        <property type="entry name" value="S1_EF-P_repeat_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05794">
        <property type="entry name" value="S1_EF-P_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00141">
        <property type="entry name" value="EF_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015365">
        <property type="entry name" value="Elong-fact-P_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020599">
        <property type="entry name" value="Transl_elong_fac_P/YeiP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013185">
        <property type="entry name" value="Transl_elong_KOW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001059">
        <property type="entry name" value="Transl_elong_P/YeiP_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013852">
        <property type="entry name" value="Transl_elong_P/YeiP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011768">
        <property type="entry name" value="Transl_elongation_fac_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30053">
        <property type="entry name" value="PTHR30053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01132">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08207">
        <property type="entry name" value="EFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09285">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005901">
        <property type="entry name" value="EF-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01185">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00841">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00038">
        <property type="entry name" value="efp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01275">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EFP" evidence="10">
        <location>
            <begin position="67"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Elong-fact-P_C" evidence="9">
        <location>
            <begin position="129"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY69823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="186" mass="20800" checksum="FDD3176D94DE3CBA" modified="2017-04-12" version="1">MASTNDLKNGMVLDLDGQLWQVLWFQHHKPGKGNTVVRSKLKHVLSGKIIDKTFNSDTKVDTATVDRREMQYLYMDGDDFVFMDNSTFEQFHVSAETVGEAKDYMLENQNAIVATHEGNPLFIELPASVELEVTYTEPGLQGDRSTGGTKPATLETGKLIQVPLFITTGERIKVDTRDGSYQGRVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEH8</accession>
    <name>A0A1Q2CEH8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06655</name>
        <name evidence="3" type="ORF">SAMN05428934_110116</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ10331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06655"/>
    <dbReference type="EnsemblBacteria" id="AQP44532">
        <property type="protein sequence ID" value="AQP44532"/>
        <property type="gene ID" value="RPIT_06655"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ10331">
        <property type="protein sequence ID" value="SDZ10331"/>
        <property type="gene ID" value="SAMN05428934_110116"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06655"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019675">
        <property type="entry name" value="DUF2550"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10739">
        <property type="entry name" value="DUF2550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ10331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="153" mass="17120" checksum="E1C1A10A4A8D0E3D" modified="2017-04-12" version="1">MPWQIAVTTVAVVAVVLLPFVLLYIRRRWLTGQGGLFDCAYRVRDDAPGVGWVLGMARYRGEDLEWFRAFSFSLKPKVTFQRASTGFIHQRHPEGIEAVALFEASMIVTVRDRLTRRVHSLAMAPESVMGLMSWLESAPPGSHYLPTSADTPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEL4</accession>
    <name>A0A1Q2CEL4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 12">Anthranilate synthase component 1</fullName>
            <ecNumber evidence="5 12">4.1.3.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">trpE</name>
        <name evidence="15" type="ORF">RPIT_06455</name>
        <name evidence="16" type="ORF">SAMN05428934_103236</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1T</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1</strain>
        </source>
    </reference>
    <reference evidence="15" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>chorismate + L-glutamine = anthranilate + H(+) + L-glutamate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:21732"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="4.1.3.27"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 12">Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the anthranilate synthase component I family.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.27" evidence="5 12"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06455"/>
    <dbReference type="EnsemblBacteria" id="AQP44495">
        <property type="protein sequence ID" value="AQP44495"/>
        <property type="gene ID" value="RPIT_06455"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71222">
        <property type="protein sequence ID" value="SDY71222"/>
        <property type="gene ID" value="SAMN05428934_103236"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06455"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005256">
        <property type="entry name" value="Anth_synth_I_PabB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="PTHR11236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00564">
        <property type="entry name" value="trpE_most"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 12" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Anth_synt_I_N" evidence="14">
        <location>
            <begin position="29"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate_bind" evidence="13">
        <location>
            <begin position="225"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="AQP44495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="SDY71222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="495" mass="53445" checksum="0C38DD69834B3F3D" modified="2017-04-12" version="1">MRITPSLEEFTELASGRRVISVHARLLADDLTPVALYDLLCGDREGTFLFESAEAGVWSRYSFVGVRSAATLTEVDGRAHWIGQELVGIDDGDPLQVLRQTLTELATPATPGLPPFHAGMVGYLGYDVVRRLERLPDTTTRDLPVPELVMMLSSEVAVLDHHLGELWLIANAINFDGTDEGVDRAYRGAVAAVEAMAEAVRRPRASRATQEGQRRALAVHRQRSSEEFRAAVEAAKEEIRAGEAFQIVVSQRFDVSTSADALDVYRALRVTNPSPYLYLLRLPGFAIVGSSPEALVTVQDGLATTRPIAGSRPRGATPDEDRRLADELLADPKERAEHLMLVDLGRNDLGRVCEPGSVTVDEFMNVHRYSHIMHLEAAVSGRVRPGLSALDATLACFPAGTLSGAPKVRAMEIIDRLEVSRRGVYGGVVGYFDFAGNSDVAIAIRTAVMADGVAHVQAGAGIVADSVPELEDAECSHKARAVLTAIARAEALGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEM2</accession>
    <name>A0A1Q2CEM2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted Zn-dependent peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_06890</name>
        <name evidence="4" type="ORF">SAMN05428934_11068</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06890"/>
    <dbReference type="EnsemblBacteria" id="AQP44572">
        <property type="protein sequence ID" value="AQP44572"/>
        <property type="gene ID" value="RPIT_06890"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09485">
        <property type="protein sequence ID" value="SDZ09485"/>
        <property type="gene ID" value="SAMN05428934_11068"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06890"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M16" evidence="1">
        <location>
            <begin position="51"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="2">
        <location>
            <begin position="182"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ09485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="435" mass="45563" checksum="1C03DC50F514CA72" modified="2017-04-12" version="1">MTRPTVGPSRPWIFPTPRVDQLRTGLTVWRFELPGQHIATFELVLPRSLSAEPTSKEGVGTVALHAVDEGTSSHPDGEIGELLEAQGATLHGSARHQYTTFGGQSPSRRLPEVLPLFAEVLREPDYAERDVAHHVEAQIAAHQSRLASPGAASRMALRRELYGPEQRAGRPASGSPATLVQLTPDDARAWHSETFTPVGATLIVAGALPDEWLEFDWAGGPAPSEAATVPPRKPGRIVVLDRPGAVQATIVAGCRTVTRDDPRWPALRIAGHALAGAFASRLNLDLRERLAYSYGVSGGFSAGPVEGQFTVAGSVRSETAADAVARILDAVALGVGLSEAEVESARRYLIDVAPLANETSADIVAQASALAAAGVAPDYLTGHLRDLAGISADEATDAFRSTVRPDDLAVAIAGDAATLVPALTTAGLAATVVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CER3</accession>
    <name>A0A1Q2CER3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07100</name>
        <name evidence="3" type="ORF">SAMN05428934_11024</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07100"/>
    <dbReference type="EnsemblBacteria" id="AQP44609">
        <property type="protein sequence ID" value="AQP44609"/>
        <property type="gene ID" value="RPIT_07100"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08476">
        <property type="protein sequence ID" value="SDZ08476"/>
        <property type="gene ID" value="SAMN05428934_11024"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07100"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="14"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ08476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="90" mass="9719" checksum="C0885B53FD28FE0D" modified="2017-04-12" version="1">MKTILIRKVMGETLRETRMCAGMTLREVSTASMVSLGYLSEIERGHKEASSEVLCAIARALDISLSDLMISISAKLATLENAHARVPVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CET3</accession>
    <name>A0A1Q2CET3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aminotransferase</fullName>
            <ecNumber evidence="4">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_06935</name>
        <name evidence="7" type="ORF">SAMN05428934_11058</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06935"/>
    <dbReference type="EnsemblBacteria" id="AQP44580">
        <property type="protein sequence ID" value="AQP44580"/>
        <property type="gene ID" value="RPIT_06935"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09250">
        <property type="protein sequence ID" value="SDZ09250"/>
        <property type="gene ID" value="SAMN05428934_11058"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06935"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="PTHR11879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="5">
        <location>
            <begin position="29"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ09250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="398" mass="43432" checksum="C0466348F62DDB53" modified="2017-04-12" version="1">MSLLDRAELAPADPILGLTEAYNSDDRPQKVNLGVGVYLDESGKVPLLDCVRTAQQRLAADAKPIGYLGIDGMPAYREAVRGLVFGEESAVLADGRVVTVQSLGGTGGLKVGADLLRQLHPSATVLISNPSWENHRALFTRAGFRVDSYRYYEPALKGIDVDAMLADLRSAEAGTIVLLHACCHNPTGYDLTPEQWDDVIAVLRERDLMPFLDMAYQGFGFGVEEDGAVVRKFVESGLSFFLATSFSKSFSLYGERIGSLSVVTGSADEAKRVLSQLKICIRTNYSNPPTQGAALVTTVLGDRELRATWESELAGMRDRIKKLRRKLVSGLEGRGIGDMCFIQEQLGMFSYSGLTSEQMIRLRQEFGIYGTDAGRMCVAALNDRNVDYVADAIAAVRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEU0</accession>
    <name>A0A1Q2CEU0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase and inactivated derivatives</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07325</name>
        <name evidence="2" type="ORF">SAMN05428934_11422</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000014">
        <property type="protein sequence ID" value="SDZ18179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44642">
        <property type="protein sequence ID" value="AQP44642"/>
        <property type="gene ID" value="RPIT_07325"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ18179">
        <property type="protein sequence ID" value="SDZ18179"/>
        <property type="gene ID" value="SAMN05428934_11422"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07325"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002514">
        <property type="entry name" value="Transposase_8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01527">
        <property type="entry name" value="HTH_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ18179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="96" mass="10862" checksum="91951223235A9389" modified="2017-04-12" version="1">MSSIRRKYTPEFKADAVQLVVVAQRPIAQVARELEINESSLGYWVKIYREQHPDPVKAPPPVEAARLAALEAEVRRLSEENAFLKKAAAFFARTQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEV6</accession>
    <name>A0A1Q2CEV6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07215</name>
        <name evidence="3" type="ORF">SAMN05428934_1101</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ07990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07215"/>
    <dbReference type="EnsemblBacteria" id="AQP44627">
        <property type="protein sequence ID" value="AQP44627"/>
        <property type="gene ID" value="RPIT_07215"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ07990">
        <property type="protein sequence ID" value="SDZ07990"/>
        <property type="gene ID" value="SAMN05428934_1101"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07215"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06588">
        <property type="entry name" value="PhnB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009725">
        <property type="entry name" value="3_dmu_93_MTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028973">
        <property type="entry name" value="PhnB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06983">
        <property type="entry name" value="3-dmu-9_3-mt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF021700">
        <property type="entry name" value="3_dmu_93_MTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="3-dmu-9_3-mt" evidence="1">
        <location>
            <begin position="6"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ07990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="161" mass="17661" checksum="126147AF7309A808" modified="2017-04-12" version="1">MTIRTNTICLWFDKDAEAAAEFYASVFPDSHVDAVRRAPADFPGGKKGDVLTVDFTVCGIPCLGLNGGPEFPQTEAFSFQIATEDQAETDRYWDAIVGNGGQESACGWCKDRWGVSWQITPRVLTEAMRSDDPGVSQRAFEAMLSMRKIDVDAIERAVTGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEY3</accession>
    <name>A0A1Q2CEY3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_07470</name>
        <name evidence="5" type="ORF">SAMN05428934_11911</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000019">
        <property type="protein sequence ID" value="SDZ21949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07470"/>
    <dbReference type="EnsemblBacteria" id="AQP44668">
        <property type="protein sequence ID" value="AQP44668"/>
        <property type="gene ID" value="RPIT_07470"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ21949">
        <property type="protein sequence ID" value="SDZ21949"/>
        <property type="gene ID" value="SAMN05428934_11911"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07470"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022567">
        <property type="entry name" value="DUF3459"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11941">
        <property type="entry name" value="DUF3459"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="3">
        <location>
            <begin position="24"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ21949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="555" mass="59936" checksum="F3E9797D6BB57781" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEZ7</accession>
    <name>A0A1Q2CEZ7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07570</name>
        <name evidence="3" type="ORF">SAMN05428934_1253</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000025">
        <property type="protein sequence ID" value="SDZ23524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44681">
        <property type="protein sequence ID" value="AQP44681"/>
        <property type="gene ID" value="RPIT_07570"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ23524">
        <property type="protein sequence ID" value="SDZ23524"/>
        <property type="gene ID" value="SAMN05428934_1253"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07570"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ23524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="425" mass="46946" checksum="A425F5F3BBE93161" modified="2017-04-12" version="1">MLPDETSPEPAPEEALFDDHAAHLPASTNRPTQAHNSSGPRNGQSDLRPATLTPGDKLEMRLARMQFFKGAYARRGINLERHFHPEPLLVTDLDLLSFDITAHLSLYKTIGEAKSGTGKSAPKPLDRAIWIAGLKRLVDADAALVITALRPSTRVRDTVRSLGVTAMSVDDLTQWENTHLNEDLDDVGSQGPGALFADARTRKSVKGEPKLERIYWFLRSEVWFLEAFQAAKRLIGALCELRDFWTPGIEDDQAAALRWMYAETLSILTLQLVALVGRYQGSNSGEWPGYARDRLAEGAIPANNQRALAAAFDTYLAHILGELRAPAIMSVETMGAFNPTPPEWANELIELIARLEGFPGLAELPRQTDLVITERLVRRRKEGTKAVAAVSVREPEEFARMRRQIAAFLRGSVGLPEAVDKALST</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF00</accession>
    <name>A0A1Q2CF00_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44694">
        <property type="protein sequence ID" value="AQP44694"/>
        <property type="gene ID" value="RPIT_07640"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07640"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="217" mass="23920" checksum="E27FD01B3AB8FAAA" modified="2017-04-12" version="1">MTNIQPATDAKSAEWLLQPGADWWHLVRYGPPGFDVYVRIAFPEDDEEEDTVRAALVTLASHTSTPDRGNVAVWEGWNGHPNPPSAPRLEIPNRKMLLFAGPLEMLRDAPAQAWGETSGIHVPPHLVWPADQGWCLACEVDEEIEFTVGCSDRVAHALASAFPGRVRRVRYGEEAPLYRDEVDAPLNDAGSRSTEEVIYLPLPRGIHGGAPRATEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF38</accession>
    <name>A0A1Q2CF38_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07715</name>
        <name evidence="2" type="ORF">SAMN05428934_1187</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000018">
        <property type="protein sequence ID" value="SDZ21352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07715"/>
    <dbReference type="EnsemblBacteria" id="AQP44707">
        <property type="protein sequence ID" value="AQP44707"/>
        <property type="gene ID" value="RPIT_07715"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ21352">
        <property type="protein sequence ID" value="SDZ21352"/>
        <property type="gene ID" value="SAMN05428934_1187"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07715"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ21352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="108" mass="11975" checksum="170B07F53D52DE42" modified="2017-04-12" version="1">MPESVIIYPKQDKLLDSSIRQKAYSFLEKLAQDDSAPGLHIEPVHTAADSRARTGRVDQQYRALLFKLTTPTSTAYVVHGIYNHDDAYTMAAKVQLTIKRTQGLAVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF54</accession>
    <name>A0A1Q2CF54_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminoglycoside 6'-N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07955</name>
        <name evidence="3" type="ORF">SAMN05428934_11331</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07955"/>
    <dbReference type="EnsemblBacteria" id="AQP44746">
        <property type="protein sequence ID" value="AQP44746"/>
        <property type="gene ID" value="RPIT_07955"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16583">
        <property type="protein sequence ID" value="SDZ16583"/>
        <property type="gene ID" value="SAMN05428934_11331"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07955"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ16583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="195" mass="22013" checksum="495E8B2B92B3C0DE" modified="2017-04-12" version="1">MDTAYPIRTDRLLLRPLRTEDVDVIVAYRNHPAVSALQDWELPVTRDRVERQVAETWVDLEPGDSRNIGIEFDGELIGDVYVGLDEHNRPGEDGVAEIGFTLRPEYQGKGCATEAAAAVVDDLVSRLGCHRIVAQLSPQNDASKRVLERLGMRPESLAPKSYWWRGQWDDNLVYAMSADDWLDRGAQRRLPTDSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF63</accession>
    <name>A0A1Q2CF63_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Proteasome accessory factor C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_08010</name>
        <name evidence="4" type="ORF">SAMN05428934_11343</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08010"/>
    <dbReference type="EnsemblBacteria" id="AQP44756">
        <property type="protein sequence ID" value="AQP44756"/>
        <property type="gene ID" value="RPIT_08010"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16836">
        <property type="protein sequence ID" value="SDZ16836"/>
        <property type="gene ID" value="SAMN05428934_11343"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08010"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028349">
        <property type="entry name" value="PafC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043839">
        <property type="entry name" value="PafC_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19187">
        <property type="entry name" value="HTH_PafC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016838">
        <property type="entry name" value="PafC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_PafC" evidence="2">
        <location>
            <begin position="5"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="WYL" evidence="1">
        <location>
            <begin position="144"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ16836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="312" mass="33948" checksum="11059366E847D6F7" modified="2017-04-12" version="1">MRSKEQLARLLRMVPYLSANQGVTTAKVAEVFGTTPRQVIRDLEVLQFCGLPGGMYDDLFDVDIEGVREDGHIFFRNADVLSRPLRLRPAEAASLITALQLVADIAGETDAASSALAKLTDAFGDEGTRLSVTVAATDPQQRAALTAAINAHSAVELTYRTPGRPGTSQAIVEPARLRLVDGFTYLDAWSRPRDAWRSYRLDRIESVEVVDDRVSERGEPPSAWFGESEARLTLTVKPAARWIAEYYPTLAVEDVEEGLRVTFPLASQAWAAGLVLRLGDDVVEVGDPEIAAVVRRRAAAALALYEPSNGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF74</accession>
    <name>A0A1Q2CF74_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD kinase</fullName>
            <ecNumber evidence="5">2.7.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-dependent NAD kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nadK</name>
        <name evidence="6" type="ORF">RPIT_08095</name>
        <name evidence="7" type="ORF">SAMN05428934_11359</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + NAD(+) = ADP + H(+) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:18629"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.23" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ17126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08095"/>
    <dbReference type="EnsemblBacteria" id="AQP44769">
        <property type="protein sequence ID" value="AQP44769"/>
        <property type="gene ID" value="RPIT_08095"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ17126">
        <property type="protein sequence ID" value="SDZ17126"/>
        <property type="gene ID" value="SAMN05428934_11359"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08095"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="71"/>
            <end position="72"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="146"/>
            <end position="147"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="187"/>
            <end position="192"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ17126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="298" mass="32518" checksum="EBC239151930D0E9" modified="2017-04-12" version="1">MNQRTIAVLVHPEREEALEKAAVFMGDLHAMGFAFLVFDSDIERLQPLVPDARIAPLDGTPAELAVVFGGDGTILRAAEWALPLGVPLLGVNLGHVGFLAELEPSDIHALPAVVERRQYLVEERLALRVKVIAADGSVSWTSPAVNEVSMEKLARERMLNVLVSIDGRPLSRWGCDGVLVSTPTGSTAYGFSAGGPVIWPDVQAMLVVPLAAHALFNRPMVLSPSSTVELDTPDYAPTLGILWCDGRRSHELQPGERVVVTSDDHQTRIARLSEQPFTTRLVKKFALPVEGWRKRSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF93</accession>
    <name>A0A1Q2CF93_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acetylornithine aminotransferase</fullName>
            <shortName evidence="2">ACOAT</shortName>
            <ecNumber evidence="2">2.6.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">argD</name>
        <name evidence="4" type="ORF">RPIT_08205</name>
        <name evidence="5" type="ORF">SAMN05428934_11534</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2-oxoglutarate + N(2)-acetyl-L-ornithine = L-glutamate + N-acetyl-L-glutamate 5-semialdehyde</text>
            <dbReference type="Rhea" id="RHEA:18049"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29123"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
            <dbReference type="EC" id="2.6.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
        <text evidence="2">Binds 1 pyridoxal phosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.11" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08205"/>
    <dbReference type="EnsemblBacteria" id="AQP44781">
        <property type="protein sequence ID" value="AQP44781"/>
        <property type="gene ID" value="RPIT_08205"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19707">
        <property type="protein sequence ID" value="SDZ19707"/>
        <property type="gene ID" value="SAMN05428934_11534"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08205"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00109"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003992">
        <property type="term" value="F:N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01107">
        <property type="entry name" value="ArgD_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004636">
        <property type="entry name" value="AcOrn/SuccOrn_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00707">
        <property type="entry name" value="argD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="2">
        <location>
            <begin position="107"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="2">
        <location>
            <begin position="218"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>N(2)-acetyl-L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>N(2)-acetyl-L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ19707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="390" mass="41011" checksum="208F68FC4AEC3082" modified="2017-04-12" version="1">MTQEELTARYGAVMMNAFGSPKRVFERGEGVHLFDADGNRYLDLLSGLAVNALGHAHPGVTRAVSEQLGRLGHVSNFFASEQQIRLAERLSALTGAERTRVFFTNSGAEANEAAFKLTRLTGRTKVIAMEGSFHGRTMGALALTHTAKYREPFEPLPGGVVFVPFGDTEALRAHADDQTAAILVETVQGENGVVPAPDGFLRDAREIADRVGALLWIDEVQTGLGRCGEWLAHRHDGVVADLVTLAKGLGNGFPVGACLASGPAVDLLQPGQHGTTFGGNPVAAAAGNAVLDALESGVLDSARNTGRWLREAVAALAHPLIDHVRGRGMLLGVVLKADVAPQIADAALTAGFVINAPRPDVIRLAPPLISTPEDLSGFVEALGSLLDAHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFC5</accession>
    <name>A0A1Q2CFC5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CHAT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08365</name>
        <name evidence="3" type="ORF">SAMN05428934_1151</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44808">
        <property type="protein sequence ID" value="AQP44808"/>
        <property type="gene ID" value="RPIT_08365"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19056">
        <property type="protein sequence ID" value="SDZ19056"/>
        <property type="gene ID" value="SAMN05428934_1151"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08365"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="719"/>
            <end position="879"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ19056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="882" mass="93667" checksum="5A2462A84BD4792F" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFH2</accession>
    <name>A0A1Q2CFH2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphopantetheine adenylyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Dephospho-CoA pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pantetheine-phosphate adenylyltransferase</fullName>
            <shortName evidence="6">PPAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">coaD</name>
        <name evidence="8" type="ORF">RPIT_08700</name>
        <name evidence="9" type="ORF">SAMN05428934_10750</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>(R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19801"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:61723"/>
            <dbReference type="EC" id="2.7.7.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the bacterial CoaD family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.3" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08700"/>
    <dbReference type="EnsemblBacteria" id="AQP44858">
        <property type="protein sequence ID" value="AQP44858"/>
        <property type="gene ID" value="RPIT_08700"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97286">
        <property type="protein sequence ID" value="SDY97286"/>
        <property type="gene ID" value="SAMN05428934_10750"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08700"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004595">
        <property type="term" value="F:pantetheine-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02163">
        <property type="entry name" value="PPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00151">
        <property type="entry name" value="PPAT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001980">
        <property type="entry name" value="PPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21342:SF1">
        <property type="entry name" value="PTHR21342:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01020">
        <property type="entry name" value="LPSBIOSNTHSS"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01510">
        <property type="entry name" value="coaD_prev_kdtB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="7">
        <location>
            <begin position="4"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="8"/>
            <end position="9"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="87"/>
            <end position="89"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="121"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY97286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="164" mass="17921" checksum="F94A75ABCE9EF144" modified="2017-04-12" version="1">MKVLCPGSFDPITVGHLDIIERAHALFGQVVIAIGNNSQKKYMFSFDERVELVRGATRDLPGVTVEPMTGLLVDFCHARGIPAVVKGLRFGADFDFELQMAHMNRDMGEIETVLLPAAKDQVTLSSTIIRQVINLGGDVTEYVPANVLAAVAARRESERNASRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFJ3</accession>
    <name>A0A1Q2CFJ3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="5 8">3.4.21.92</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Endopeptidase Clp</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 11" type="primary">clpP</name>
        <name evidence="11" type="ORF">RPIT_08805</name>
        <name evidence="12" type="ORF">SAMN05428934_10771</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 9">Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 10">Belongs to the peptidase S14 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="5 8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08805"/>
    <dbReference type="EnsemblBacteria" id="AQP44878">
        <property type="protein sequence ID" value="AQP44878"/>
        <property type="gene ID" value="RPIT_08805"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97753">
        <property type="protein sequence ID" value="SDY97753"/>
        <property type="gene ID" value="SAMN05428934_10771"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08805"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033135">
        <property type="entry name" value="ClpP_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018215">
        <property type="entry name" value="ClpP_Ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00382">
        <property type="entry name" value="CLP_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00381">
        <property type="entry name" value="CLP_PROTEASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 8" id="KW-0720">Serine protease</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 7">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY97753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="199" mass="22210" checksum="FDB9793503E1720A" modified="2017-04-12" version="1">MNYYIPQWEERTSYGMRRVDPYTKLFEDRIIFLGTPINDEVANAVMAQLLCLQSMDPERQISIYINSPGGSFTALTAIYDTMRYIKPDIQTVCLGQAASAAAVLLAAGTKGKRLALPNSRILIHQPATEGGYGQSSDLEIQAKEILRIRSLMETMLANDTGQELEKITKDIERDKYLTAAEAVEYGIVDDILPSLKELN</sequence>
</entry>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="SDY97882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="84" mass="9334" checksum="56CF2E37F5EC38A4" modified="2017-04-12" version="1">MTDDQRPRRQLLTGIAAPTLADSFDDVRFTPAAFSQHGPTHVLSASPLQVITRHRLDTGAVVDLTLVRNPVSRHGWIVIRVTEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFR5</accession>
    <name>A0A1Q2CFR5_9ACTN</name>
    <protein>
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        <alternativeName>
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        </alternativeName>
    </protein>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class I fructose-bisphosphate aldolase family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="SAMN05428934_107150"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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    </dbReference>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00029799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
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            <dbReference type="EMBL" id="AQP44937.1"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="296" mass="33008" checksum="CD365B5D1057CDF1" modified="2017-04-12" version="1">MFEQQLHKMRDAEGFIAALDQSGGSTPKALRLYGLESWADDEEMFDKVHEMRTRIMMSPSFDGKRILGTILFQDTLARQVDGRPTADYLWNVKGIVPILKVDKGLLDMEAGARLMRPMPDLDAVLAAALEQGVFGTKMRSVILEPGGGLAAVVEQQFDVGEHIFRAGLVPILEPEIDIHSPLKAEAEEQLHDALLSHLDQLPDDHWVMLKLTLPETDDLYLDLVRHPRVLRVFALSGGYTRAEANERLARQHGIVASFSRALTEGLSVHQSAQEFDALLDESIRSIFDASRSPMEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFU0</accession>
    <name>A0A1Q2CFU0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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        <name evidence="3" type="ORF">SAMN05428934_102427</name>
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
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    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
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    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">RP1</strain>
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    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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        <property type="protein sequence ID" value="SDY60470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09400"/>
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        <property type="gene ID" value="RPIT_09400"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY60470"/>
        <property type="gene ID" value="SAMN05428934_102427"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
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    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="124"/>
        </location>
    </feature>
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        <location>
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            <end position="148"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY60470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="255" mass="27518" checksum="B0E9D8A600217562" modified="2017-04-12" version="1">MTTREITAPEQRKLRTLNLAAAALHLAQAIAVVILATDFALPITASYLAGPPGTPPGPATVLADLPTGLAVAGFLFLSFLAHLIVGTVWFRNYIGDLSQLINRARWVEYSFSSTLMIVVISQLVGITDVAALIAICGANVSMILFGWLQEKYETPGSGGWLPFIFGCIAGVVPWLAILYYTIAPGSDAEPPGFVYAIVVSLFLFFNVFGLNQWLQYRAKGRWADYLVGERSYIILSLVAKSLLAWQVFGGTLAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFX4</accession>
    <name>A0A1Q2CFX4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09320</name>
        <name evidence="3" type="ORF">SAMN05428934_102445</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY60979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44960">
        <property type="protein sequence ID" value="AQP44960"/>
        <property type="gene ID" value="RPIT_09320"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY60979">
        <property type="protein sequence ID" value="SDY60979"/>
        <property type="gene ID" value="SAMN05428934_102445"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09320"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY60979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="265" mass="29172" checksum="3FB5B2BB4FDC7126" modified="2017-04-12" version="1">MRGIEQVLDLHTTQRGTRPGPIPGTIFVDGGLFKDTLPKDLRSLGGFSLGVSAEAKALLAAQYDRRKYHAFTPMGAPNYARATQRYRDPVLSGTMRCANHPASLRLDAARYPQTQCVEGEPCHCGTTVTLGPDDQLNLRQRVLYGTTKWKASYGRRSVVESTNACAKVHHARLTRHSTRVRGTERNGILLSFILAAVNASILLTRYGYDVGDPPQVADDEVIEPLPSARPTKALHRQRKFSRPRRAQAPPGPAYTGPPPRRPGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG02</accession>
    <name>A0A1Q2CG02_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peroxiredoxin</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Peroxiredoxin Q/BCP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_09410</name>
        <name evidence="6" type="ORF">SAMN05428934_102425</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY60421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09410"/>
    <dbReference type="EnsemblBacteria" id="AQP44975">
        <property type="protein sequence ID" value="AQP44975"/>
        <property type="gene ID" value="RPIT_09410"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY60421">
        <property type="protein sequence ID" value="SDY60421"/>
        <property type="gene ID" value="SAMN05428934_102425"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09410"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="5"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="3">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY60421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="159" mass="17098" checksum="BB89B8FCABD4447F" modified="2017-04-12" version="1">MTARLTPGSTAPEFTLPNQDGDDVSLADYAGKSVILYFYPAAMTPGCTTQAVDFSSAIDAFTENGYTVLGCSPDPVEKLAKFSANSDIDFTLLADPEKKVLDLYGAYGLRKLYGKEIEGVLRSTFVIDVDDDGTGTVRIAQYNVKATGHVAKLRRELGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG33</accession>
    <name>A0A1Q2CG33_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Phosphomannomutase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">Phosphomannomutase/phosphoglucomutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">manB</name>
        <name evidence="11" type="ORF">RPIT_09575</name>
        <name evidence="12" type="ORF">SAMN05428934_102391</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY59530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09575"/>
    <dbReference type="EnsemblBacteria" id="AQP45005">
        <property type="protein sequence ID" value="AQP45005"/>
        <property type="gene ID" value="RPIT_09575"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59530">
        <property type="protein sequence ID" value="SDY59530"/>
        <property type="gene ID" value="SAMN05428934_102391"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09575"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016868">
        <property type="term" value="F:intramolecular transferase activity, phosphotransferases"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="8">
        <location>
            <begin position="5"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="9">
        <location>
            <begin position="152"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="10">
        <location>
            <begin position="260"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="7">
        <location>
            <begin position="370"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP45005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY59530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="449" mass="48553" checksum="88AA9FBC3F60718E" modified="2017-04-12" version="1">MLDPKIFKANDIRGIVVGPDAQWDAHGARQLGAAYAQLLTPEEFVLGRDMRVLGEELAEAFADGARRAGASVVDIGLSSTDQLWFASGWLGIPGVQLTASHNPAEYNGIKFCLADARPVPADFLTRLRHAASEVQVGGDVTGGYRELDALGPYADKLTELVPRRGGRELIVVVDAGNGMAGHTAQRALSGRSVEIVGLYLELDGSFPNHPANPLEPENLEDAQRAVIEHRADLGLVFDGDADRCFIIDERGQVVDPSVITAMIAVAELDKYPGSTIVTNTITSWSVAQAVAERGGEIASSKVGHTYVKALMAETGAVFGGEHSAHYYFRDFWSADTGMLAALHVIEMVREASVPLSELAAVYDGYVRSGELNSTVDDATAVMESVADVFSGRGEVDWVDGLTVRNLDEQWWLNVRPSNTEPLLRLNVEARDVVTMERLRDEVLDLVRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGH7</accession>
    <name>A0A1Q2CGH7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10715</name>
        <name evidence="3" type="ORF">SAMN05428934_102162</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY52960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45207">
        <property type="protein sequence ID" value="AQP45207"/>
        <property type="gene ID" value="RPIT_10715"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY52960">
        <property type="protein sequence ID" value="SDY52960"/>
        <property type="gene ID" value="SAMN05428934_102162"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10715"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544479" evidence="1">
        <location>
            <begin position="29"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY52960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="164" mass="17308" checksum="42552D78665C9179" modified="2017-04-12" version="1">MKLTRLVPLVAAAALFAACSPTAGTALVVDGASYSESDIDRTVQGCADAMGVTPQDIVRPAVVQSLLLGGVFDRLADEYGHLSTETIDEVAAQGEFASMMQSQDCLPLIRASVKTSLLQQVDFEAVQTAARQADVQLNPRYGKWIPEDPALMDVSPSLSVPAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGI5</accession>
    <name>A0A1Q2CGI5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Bifunctional protein GlmU</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="15">UDP-N-acetylglucosamine pyrophosphorylase</fullName>
                <ecNumber evidence="15">2.7.7.23</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="15">N-acetylglucosamine-1-phosphate uridyltransferase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="15">Glucosamine-1-phosphate N-acetyltransferase</fullName>
                <ecNumber evidence="15">2.3.1.157</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="15" type="primary">glmU</name>
        <name evidence="18" type="ORF">RPIT_10745</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:13509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="2.7.7.23"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>acetyl-CoA + alpha-D-glucosamine 1-phosphate = CoA + H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13725"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="ChEBI" id="CHEBI:58516"/>
            <dbReference type="EC" id="2.3.1.157"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="15">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route II): step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">In the C-terminal section; belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.23" evidence="15"/>
    <dbReference type="EC" id="2.3.1.157" evidence="15"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10745"/>
    <dbReference type="EnsemblBacteria" id="AQP45213">
        <property type="protein sequence ID" value="AQP45213"/>
        <property type="gene ID" value="RPIT_10745"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10745"/>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00532"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019134">
        <property type="term" value="F:glucosamine-1-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003977">
        <property type="term" value="F:UDP-N-acetylglucosamine diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03353">
        <property type="entry name" value="LbH_GlmU_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01631">
        <property type="entry name" value="GlmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005882">
        <property type="entry name" value="Bifunctional_GlmU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038009">
        <property type="entry name" value="GlmU_C_LbH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01173">
        <property type="entry name" value="glmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 15" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10 15" id="KW-0133">Cell shape</keyword>
    <keyword evidence="14 15" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11 15" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 15 18" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="17">
        <location>
            <begin position="29"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyrophosphorylase" evidence="15">
        <location>
            <begin position="1"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-GlcNAc binding" evidence="15">
        <location>
            <begin position="32"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-GlcNAc binding" evidence="15">
        <location>
            <begin position="104"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Linker" evidence="15">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-acetyltransferase" evidence="15">
        <location>
            <begin position="277"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Acetyl-CoA binding" evidence="15">
        <location>
            <begin position="411"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="476"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="388"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="391"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="402"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="430"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="AQP45213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="507" mass="53239" checksum="2D85F37CE1EDABB2" modified="2017-04-12" version="1">MRAAARACIGPKERLPLSTDNELAPVAAVVVLAAGGGTRMKSKKSKLLHEVAGKPMLAYAVSAAAALNPEHLVVVVGHQREEVTSHLEKLSESVTTAVQDEQLGTGHAVSCGLADLGELEGDVVVTYADVPMLNGDTLRQLVAVHRAHHNSATVLTASVEDPTGYGRILRDGETVTGIVEHRDATEDQRAITEINSGIYVFRAETLREGLASLSTDNSQGEQYLTDVVHFAHGRAERVGAHLLDDVWQTEGVNDRVQLARINAEMNRRIRDAWMLKGVTMIDPSSTWIDVDVDLAPDVVLHPGVILQGATTIGEGAIIGPDTTLMDVEVGPGAEVVRTHGSFAVIGEGATVGPFTYLRPGTILGKGGKIGGFVETKNAVIADGAKVPHLSYVGDAFVDEGANIGAGTIFANYDGVHKSSTHVGKNAFVGSNSVLVAPVDIAPGAFVAAGSTITDDVPAGGLAVARGRQRNIEGWVENRRPDSKAASAAAEHDGEIHPAVNESRQKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGI9</accession>
    <name>A0A1Q2CGI9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tat proofreading chaperone TorD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10820</name>
        <name evidence="2" type="ORF">SAMN05428934_102140</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY52229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10820"/>
    <dbReference type="EnsemblBacteria" id="AQP45226">
        <property type="protein sequence ID" value="AQP45226"/>
        <property type="gene ID" value="RPIT_10820"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY52229">
        <property type="protein sequence ID" value="SDY52229"/>
        <property type="gene ID" value="SAMN05428934_102140"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10820"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020945">
        <property type="entry name" value="DMSO/NO3_reduct_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036411">
        <property type="entry name" value="TorD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02613">
        <property type="entry name" value="Nitrate_red_del"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89155">
        <property type="entry name" value="SSF89155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY52229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="200" mass="22074" checksum="AD3033C52C0936FA" modified="2017-04-12" version="1">MDAVDLDRRAAALTVLSRLLLTAPSADVVAALRDPERLADWPTPEGAQEGLELLAASREDDEAIRIDHQRLFGGAGRAKANPFESVHRSREGLKFEAETLQVRAAYRELGLQAPRLNKEPDDHIGLELEFVAAAYLRAVELLDAGESAQDVLAVADRFIRDHLVQWAPNLFRMVVEGAETDFYRGVGYLGGALMEQLRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGK5</accession>
    <name>A0A1Q2CGK5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Restriction endonuclease subunit R</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Type I restriction enzyme, R subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_10865</name>
        <name evidence="4" type="ORF">SAMN05428934_102131</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY51974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10865"/>
    <dbReference type="EnsemblBacteria" id="AQP45233">
        <property type="protein sequence ID" value="AQP45233"/>
        <property type="gene ID" value="RPIT_10865"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY51974">
        <property type="protein sequence ID" value="SDY51974"/>
        <property type="gene ID" value="SAMN05428934_102131"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10865"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006304">
        <property type="term" value="P:DNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025285">
        <property type="entry name" value="DUF4145"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013670">
        <property type="entry name" value="EcoEI_R_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029464">
        <property type="entry name" value="HSDR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13643">
        <property type="entry name" value="DUF4145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08463">
        <property type="entry name" value="EcoEI_R_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13588">
        <property type="entry name" value="HSDR_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="364"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="151"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY51974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="1116" mass="123523" checksum="01DB877391A053B1" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGK7</accession>
    <name>A0A1Q2CGK7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10935</name>
        <name evidence="3" type="ORF">SAMN05428934_102116</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY51544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45246">
        <property type="protein sequence ID" value="AQP45246"/>
        <property type="gene ID" value="RPIT_10935"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY51544">
        <property type="protein sequence ID" value="SDY51544"/>
        <property type="gene ID" value="SAMN05428934_102116"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10935"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544488" evidence="1">
        <location>
            <begin position="29"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY51544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="335" mass="36394" checksum="25904E0FC1BD7A4F" modified="2017-04-12" version="1">MKLAPRLAALAAAAAIAFTGLTTQSARAADADVYTTPGGHLVNGRLWKTDCEMYSSNVVRCRTEIYAKTVVRQGGSYTTAYRWAFNNLTYLPSHRSQWADNPLAKTGTFTSQGRQWRTECDTPATGSGACRSYIKTTFVAYEGGKYVTKNEFVFNNLVRFAQGSIAPVTTIPAHVIDQSRLDFNGLGPVKIGTKFSDLGLLGYADYVTSDVCEPRWRVSNFLKTRGIDPSDGDRNSSVWYVSLTKPGAKTVAGAEVGMTVGQIKALYGSSFTVVPKTNYGETQYFGSVRDGGRELLFRAAGAGGSYAPDRALVNSDVIVEIRAWNFADDVSYDSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGL4</accession>
    <name>A0A1Q2CGL4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoribosylglycinamide formyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10920"/>
    <dbReference type="EnsemblBacteria" id="AQP45243">
        <property type="protein sequence ID" value="AQP45243"/>
        <property type="gene ID" value="RPIT_10920"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10920"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007351">
        <property type="entry name" value="YjbR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038056">
        <property type="entry name" value="YjbR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04237">
        <property type="entry name" value="YjbR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142906">
        <property type="entry name" value="SSF142906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="130" mass="14591" checksum="C9ACCB6200A995A6" modified="2017-04-12" version="1">MGHPLMFDDEDPILDRVRETALALPGAAEKVSHGRPAFFTTKVFAYYGGSIKIDGAYEQHDQSLVVHPDEEEVRSLTEEDRCYRPAYLGPSGWIGVDLDDKTDWTEVSELIEASYRMTASARLIAELDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGP3</accession>
    <name>A0A1Q2CGP3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_10850</name>
        <name evidence="6" type="ORF">SAMN05428934_102134</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY52057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10850"/>
    <dbReference type="EnsemblBacteria" id="AQP45230">
        <property type="protein sequence ID" value="AQP45230"/>
        <property type="gene ID" value="RPIT_10850"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY52057">
        <property type="protein sequence ID" value="SDY52057"/>
        <property type="gene ID" value="SAMN05428934_102134"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10850"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022749">
        <property type="entry name" value="D12N6_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038333">
        <property type="entry name" value="T1MK-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12161">
        <property type="entry name" value="HsdM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HsdM_N" evidence="4">
        <location>
            <begin position="6"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="N6_Mtase" evidence="3">
        <location>
            <begin position="136"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY52057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="488" mass="54556" checksum="EA1BFC99C30C4C98" modified="2017-04-12" version="1">MITGELKSKIDRVWDAFWSGGISNPLEVIEQITYLLFVRRLDDIHTLAEKRARRIGGLEGAVFTESQEHLRWKNLKNLEPAQMHATVADEVFPFLRTLGGDGSTYSEHMRDARFTIPTPALLSRVVDMLDGIAMDDRDTNGDLYEYLLSKIASAGVNGQFRTPRHIIQLMVDMTAPRPDDEICDPACGTAGFLIAASEYIRHQHPEALLDATQRRHFHHSMFHGYDFDATMLRIGSMNMLLHGIEAPDIRYRDSLSEGASGDAEKYSLILANPPFAGSLDYESTAKDLQRIVKTKKTELLFMALFLKLLKPGGRAAVIVPDGVLFGSSKAHKDLRRALVEDQKLDAVVKLPSGVFRPYAGVSTAILFFTKTDSGGTDDVWFYDVQADGFSLDDKRNPVEANDLPDVLERWQSLAKPDSPERGRARTEQSFLVPKADIVAQGYDLSINRYKEIVHDEEEHRPPLEIIADIETLEAEISAGIAELKAMLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGP5</accession>
    <name>A0A1Q2CGP5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator, OmpR family, contains REC and winged-helix (WHTH) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_10755</name>
        <name evidence="6" type="ORF">SAMN05428934_102154</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY52717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10755"/>
    <dbReference type="EnsemblBacteria" id="AQP45215">
        <property type="protein sequence ID" value="AQP45215"/>
        <property type="gene ID" value="RPIT_10755"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY52717">
        <property type="protein sequence ID" value="SDY52717"/>
        <property type="gene ID" value="SAMN05428934_102154"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10755"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="124"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="124"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY52717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="217" mass="23714" checksum="476E9D9FEAB24DA1" modified="2017-04-12" version="1">MRVLVVDDERSLTRVLQRGLAAEGFAVDVAHDGDSGLTLATHGDYDAIVLDIMLPRLNGYAVTAELRKRGVWTPVLMLSAKDGEYDVADALDLGADDYLTKPFSFVVLVARLRALVRRPSGARPAVLEVGSVTLDPSTRTVTLDGAPVELTTREVALLEYLMRHSDRVVGKVELRDHVWEGTGEDLNVVEVYVGYLRRKLGRDVIATVRGAGYRAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGS9</accession>
    <name>A0A1Q2CGS9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methylmalonyl-CoA carboxyltransferase 5S subunit</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Oxaloacetate decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11370</name>
        <name evidence="3" type="ORF">SAMN05428934_10229</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY48871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11370"/>
    <dbReference type="EnsemblBacteria" id="AQP45321">
        <property type="protein sequence ID" value="AQP45321"/>
        <property type="gene ID" value="RPIT_11370"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY48871">
        <property type="protein sequence ID" value="SDY48871"/>
        <property type="gene ID" value="SAMN05428934_10229"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11370"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003379">
        <property type="entry name" value="Carboxylase_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02436">
        <property type="entry name" value="PYC_OADA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY48871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="497" mass="54348" checksum="2639CE5D21E8626A" modified="2017-04-12" version="1">MSARKIGVTELALRDAHQSLMATRMAMEDMVDACEDIDQAGYWSVECWGGATFDACIRFLNEDPWKRLRTFRELMPNSRLQMLLRGQNLLGYRHYEDMVVEKFVEKSAENGMDVFRVFDALNDPRNMAKAMQAVKDVGKHAQGTICYTISPVHTVEGYIKLAGQLIDMGAESIALKDMAALLQPQPAYDIVRGIKETYGDIQINVHCHSTTGVTLVSLMKAIEAGADVVDTAISSMSLGPGHNPTESLVAMLEGTGYETGLDMERLLRIRDHFAEVRPKYAEFESATLVDTDIFSSQIPGGMLSNMESQLKAQGAGDRIREVMLEVPKVKADAGHPPLVTPSSQIVGTQAVFNVLMGRYKVMTGEFADLMLGYYGECLGERNAEVVEMAKAQAKKDVIADRPADHLDPEWGALEAAAAKLEGFDGSAEDVLTNAMFPGVAPKFFETRHEGPKNVSKTPAQLAAERAKASGDRPGITGPVQYNVKIAGREHSVSVEPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGW0</accession>
    <name>A0A1Q2CGW0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GyrI-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11580</name>
        <name evidence="3" type="ORF">SAMN05428934_106159</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY94168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11580"/>
    <dbReference type="EnsemblBacteria" id="AQP45358">
        <property type="protein sequence ID" value="AQP45358"/>
        <property type="gene ID" value="RPIT_11580"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY94168">
        <property type="protein sequence ID" value="SDY94168"/>
        <property type="gene ID" value="SAMN05428934_106159"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11580"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029442">
        <property type="entry name" value="GyrI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008319">
        <property type="entry name" value="UCP031644"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06445">
        <property type="entry name" value="GyrI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031644">
        <property type="entry name" value="UCP031644"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GyrI-like" evidence="1">
        <location>
            <begin position="24"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY94168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="203" mass="22471" checksum="6458E127D876F8A0" modified="2017-04-12" version="1">MKFDVKKDRKDLYQPRAGEIVEADVPLMRFLAIDGHGDPNSAPAYESGLQALYSTAYAIKFAFRDRTGDDFVVGPLEGLWYADDPAVFASGEKSEWKWTIMLPLPDAVVDADATAGFGSAAAKKPDLPIAELRIQELREGRCLQVMHTGAYADEGPVIARLHARMEAAGLTWNGPHHEIYLSDPRRVAPDKLRTVLRQPVRPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGY3</accession>
    <name>A0A1Q2CGY3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LysR_substrate domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_11615</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11615"/>
    <dbReference type="EnsemblBacteria" id="AQP45364">
        <property type="protein sequence ID" value="AQP45364"/>
        <property type="gene ID" value="RPIT_11615"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11615"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysR_substrate" evidence="2">
        <location>
            <begin position="36"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="218" mass="24465" checksum="CDCBAACC8861E76B" modified="2017-04-12" version="1">MTDRQPPAPNVLRVGFVPGVTLTKWRRIWAERFRQPLEVVEVEQDNQRRALLSDDVDMCFVRLPVDREGLHVIPLYDEQPVLWLSKDHLLAALDEVTADDLADVRVIHDSQPESIELAAYSAAVLRVPMSIARTGSRRDMLYLPVVDAEPTTIGLAWLTDNPNPLIEEFIGVVRGRTVNSTRTTQARGGVESPQRPRKNPAPGGPASKTRGAKRPRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH75</accession>
    <name>A0A1Q2CH75_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Two-component system, OmpR family, response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_12140</name>
        <name evidence="6" type="ORF">SAMN05428934_10648</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY91714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12140"/>
    <dbReference type="EnsemblBacteria" id="AQP45461">
        <property type="protein sequence ID" value="AQP45461"/>
        <property type="gene ID" value="RPIT_12140"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY91714">
        <property type="protein sequence ID" value="SDY91714"/>
        <property type="gene ID" value="SAMN05428934_10648"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12140"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="13"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="138"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="138"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY91714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="238" mass="26410" checksum="702685D6F4273545" modified="2017-04-12" version="1">MASLTRPDGTPIRVLAVDDEPSLIELLSMAMRYEGWDVTTAATGGDAVRAARETHPDALVLDIMLPDFDGLEVMRRIRAEQPDVPVIFLTAKDGVTDRIAGLTAGGDDYVTKPFSLEELIARLRGLLRRSGATTARPDTQLVVGDLILDEESREVTRAGEPISLTATEFELLRFLMRNPKRVLSKAQILDRVWNYDFGGQANVVELYISYLRKKIDANREPMIHTMRGAGYVLRPAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHA1</accession>
    <name>A0A1Q2CHA1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45492">
        <property type="protein sequence ID" value="AQP45492"/>
        <property type="gene ID" value="RPIT_12340"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12340"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="166" mass="16954" checksum="57CEBDDE7203B30A" modified="2017-04-12" version="1">MPTAPAPSTAGGLSEADLTVPDGWEPTARPGSPEEGYLGNGTWVHATSPEHSAYAAIALGCTDVGAYPTPVAALEGTIVGPDGQPGVGLALEFGSQDDAAAYFAEWTRQAEACVGTVTEKVSLDDETWVGRRLLDTVWSEAVALSGTSVRLLILDDPDADVAAAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHG8</accession>
    <name>A0A1Q2CHG8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Haloacid dehalogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="13">Plasma-membrane calcium-translocating P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_12680</name>
        <name evidence="13" type="ORF">SAMN05428934_104151</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY79192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12680"/>
    <dbReference type="EnsemblBacteria" id="AQP45554">
        <property type="protein sequence ID" value="AQP45554"/>
        <property type="gene ID" value="RPIT_12680"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY79192">
        <property type="protein sequence ID" value="SDY79192"/>
        <property type="gene ID" value="SAMN05428934_104151"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12680"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="SSF81660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="287"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="725"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="756"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="796"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="838"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="870"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="902"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="domain" description="Cation_ATPase_N" evidence="11">
        <location>
            <begin position="8"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP45554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY79192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="944" mass="100105" checksum="38C858191A367ED2" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHH5</accession>
    <name>A0A1Q2CHH5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4031 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12805</name>
        <name evidence="3" type="ORF">SAMN05428934_104126</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY78450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45576">
        <property type="protein sequence ID" value="AQP45576"/>
        <property type="gene ID" value="RPIT_12805"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY78450">
        <property type="protein sequence ID" value="SDY78450"/>
        <property type="gene ID" value="SAMN05428934_104126"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12805"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025109">
        <property type="entry name" value="DUF4031"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13223">
        <property type="entry name" value="DUF4031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4031" evidence="1">
        <location>
            <begin position="2"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY78450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="92" mass="10373" checksum="8AD3120AA1507303" modified="2017-04-12" version="1">MILIDPPRWPAHGTVFGHLVSDESLEELHAFARSNAVPERAFDRDHYDVPIVRYDDLVAAGAQPVGEKELVRRLIASGLRVRRRIPPPQQSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHJ8</accession>
    <name>A0A1Q2CHJ8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">ABC-2 type transport system ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_12575</name>
        <name evidence="6" type="ORF">SAMN05428934_104171</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
    <sequence length="296" mass="32092" checksum="7C2D5D71F4CAC697" modified="2017-04-12" version="1">MTNAIEIRDLTKTFGRTVALDRLTLDVDSGQVHGFLGPNGAGKTTTIRVLLGLLRPDSGEARVLGGHPIHDAVELHRRIAYVPGDVELWPQLTGGEAIDVLSRLRGDADPARVAELSERFDLDRTKKGRTYSKGNRQKVALVAALASNADLFILDEPTSGLDPLMEAIFQDEVRHLVSRGATVLLSSHILGQVEALADTVSIIREGAIVETGTLDSMRHLRRTTVQATTAQAPDGIAEMPGVHDVHLTGDRLTMEVDGEHIGPVMQRLTTAGLRSIVAHPPTLEQMLLRHYGDADR</sequence>
</entry>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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                <person name="Schumann P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
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<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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    <reference evidence="6 8" key="2">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45749">
        <property type="protein sequence ID" value="AQP45749"/>
        <property type="gene ID" value="RPIT_13815"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12273">
        <property type="protein sequence ID" value="SDZ12273"/>
        <property type="gene ID" value="SAMN05428934_11137"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13815"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="4">
        <location>
            <begin position="13"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="3">
        <location>
            <begin position="186"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDZ12273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="376" mass="40994" checksum="94B1089CB0411B40" modified="2017-04-12" version="1">MPRIVHILFGGLGGHGSVVFSLIKASRGAALHELAFVSTGELLTDYRAKCERDGITYVHERTSGGADFGFQWRLFRWILARRPDTVVVHSTGSVGAALAVKLLRWHTRIVVVEHQSWDLRGRRYNIATTLSLLAADNVLVLNEDYVRKLRGHFPRVSRRVSIDVVRNGIDTDHYVPRPMPSWPAETLLIGMQSRIIPIKDHATLIRAIHLLRERGLDVHLELAGDGSSRGDLEALVSDLDLRDRVTFRGMLNESELVEFLQGLDIYVHASLGEAMSTALLQAMSCGLPVVASDVPGIADLVAGSDAAILVPPQSPEPLADVVASLCADPKGRESLGKAAREFVMSGYSLDAMWQSYGPFLVGTHGRRSAGRGGSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI40</accession>
    <name>A0A1Q2CI40_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PS_pyruv_trans domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_14035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14035"/>
    <dbReference type="EnsemblBacteria" id="AQP45782">
        <property type="protein sequence ID" value="AQP45782"/>
        <property type="gene ID" value="RPIT_14035"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14035"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007345">
        <property type="entry name" value="Polysacch_pyruvyl_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04230">
        <property type="entry name" value="PS_pyruv_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PS_pyruv_trans" evidence="2">
        <location>
            <begin position="61"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="288" mass="32624" checksum="A9304E8FC477CA1A" modified="2017-04-12" version="1">MAMFGPSHSVPNPVISEDTLVAYNVETSVDRMGAAVADAELNYRAVYFPQDLQTLGLMLWGSKRSPMRRDRRLPIWAGHPQFRSGTAEFMLDADSWIGRLRSFDFSFGTRIHGNIAALLAGVPSLTIPHDSRTAELAEYHQLARYAPAREEFMTVAQLVEWFSADAMNRATRSNFERLRSFLHENGLESIFDPGQEQALRLYESTIQQNLPQEPVRCRWVGLDSQDRRALWRQRPRHLEPALRRGVTNRAARAIRRHHYERLRASSTLGNAAAGAGQDPPSAKSRDRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI80</accession>
    <name>A0A1Q2CI80_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14245</name>
        <name evidence="3" type="ORF">SAMN05428934_11231</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ14779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45821">
        <property type="protein sequence ID" value="AQP45821"/>
        <property type="gene ID" value="RPIT_14245"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ14779">
        <property type="protein sequence ID" value="SDZ14779"/>
        <property type="gene ID" value="SAMN05428934_11231"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14245"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ14779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="60" mass="6608" checksum="B7020D715DFE2312" modified="2017-04-12" version="1">MHENFHKAVALWVEATQPRPRDERGLSQSTENAILLAGAVAVAALIIGIITVYVERNLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI93</accession>
    <name>A0A1Q2CI93_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0246 protein RPIT_14380</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14380</name>
        <name evidence="3" type="ORF">SAMN05428934_11258</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0246 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ15277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45846">
        <property type="protein sequence ID" value="AQP45846"/>
        <property type="gene ID" value="RPIT_14380"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ15277">
        <property type="protein sequence ID" value="SDZ15277"/>
        <property type="gene ID" value="SAMN05428934_11258"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14380"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00652">
        <property type="entry name" value="UPF0246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005583">
        <property type="entry name" value="YaaA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30283">
        <property type="entry name" value="PTHR30283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03883">
        <property type="entry name" value="H2O2_YaaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ15277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="256" mass="28816" checksum="BB25FD9C0FA8C7FB" modified="2017-04-12" version="1">MLSVLSPAKSLDFETPLPTRKHSEPRLVGQSAGLIEIMRTKSPGEIKALMHISDDLAELNASRYSAFSTDHAPDNSRPAVLAFDGDVYQGLAAKDFDARDFTEAQKTVRILSGLYGLLRPMDLIQPHRLEMGTRLASSRGQTLYEWWGTQVTDLLRRDLEASPGPEVLINLASQEYFKVVDEHRLGARVISPRFEDRDKSGEPRVVSFYAKRARGLMAAWLVRERVRSAAKVLDFEADGYSYDEERSTKDTPVFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIB8</accession>
    <name>A0A1Q2CIB8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45876">
        <property type="protein sequence ID" value="AQP45876"/>
        <property type="gene ID" value="RPIT_14545"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14545"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010693">
        <property type="entry name" value="Divergent_4Fe-4S_mono-cluster"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06902">
        <property type="entry name" value="Fer4_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="20"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="220" mass="23663" checksum="37EE3E3720F753CF" modified="2017-04-12" version="1">MVVTWDGADGVLSGEVAGWALDSATDAIIVIDGEGLVRAWNRACVDLFGFTKEYAVGRDVDFMIPPRLRDGHHRGFTSAMERGALASDGAARRTKSLRADGGTVYIDMTFAMLHDDRGTAIGAVAVARPASDRDTPTHGRKRYRGQLVDVTFDSALCNHNGQCVRNMPEVFDTSKRPWINPEAAESPADAERLRTTVFNCPTGALQILAPDAPDDDASAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIF0</accession>
    <name>A0A1Q2CIF0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Band 7 protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">SPFH domain / Band 7 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_14290</name>
        <name evidence="5" type="ORF">SAMN05428934_11240</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ14960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14290"/>
    <dbReference type="EnsemblBacteria" id="AQP45830">
        <property type="protein sequence ID" value="AQP45830"/>
        <property type="gene ID" value="RPIT_14290"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ14960">
        <property type="protein sequence ID" value="SDZ14960"/>
        <property type="gene ID" value="SAMN05428934_11240"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14290"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="3">
        <location>
            <begin position="96"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ14960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="328" mass="35379" checksum="433FF188F104148C" modified="2017-04-12" version="1">MTLPQTPDPSTDLDGDSVGGNTSVRPVGREGARVDIEEKKAWYIDGILAFFVALVVLGLASWQFVVAAMALDVGDAGGLRMFLAILLFLLALVMFSSLTIISPGDTKVIQFFGRYIGTIRRAGLLMTVPFTTKKKVSVKVRNFETNELKVNDADGNPVNIAAIVVWQVADTAKSVFAVEQYDEFVAVQSESALRHVATTHPYDYAGPGEESLRGSTELVADELADEVAARIAIAGLEVVETRISSLAYAPEIAQAMLQRQQASAIIAAREKIVEGAVSMVENALERLEEKNVVSLDEERKAAMVSNLLVVLTSESRVTPVVNTGSLYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIF7</accession>
    <name>A0A1Q2CIF7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5 6">Heat-shock protein Hsp20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_14795</name>
        <name evidence="6" type="ORF">SAMN05428934_10961</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14795"/>
    <dbReference type="EnsemblBacteria" id="AQP45916">
        <property type="protein sequence ID" value="AQP45916"/>
        <property type="gene ID" value="RPIT_14795"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05739">
        <property type="protein sequence ID" value="SDZ05739"/>
        <property type="gene ID" value="SAMN05428934_10961"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14795"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="4">
        <location>
            <begin position="17"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="125"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDZ05739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="148" mass="16471" checksum="6C9BF47782B8889F" modified="2017-04-12" version="1">MARTFDPFREMDRLFSDVSRSAATSLDLYRTGEKFVAEIDLPGVDPSSIDIDIEERTLTVRAERKSRTDSGEDTKWLVRERPNGTFARQLNLGYGLAVDKIEAEYSDGVLTLTIPVAEEARPRKVSVTHKGGQHEITGEVAPDDESGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIH1</accession>
    <name>A0A1Q2CIH1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl esterase/lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14525</name>
        <name evidence="3" type="ORF">SAMN05428934_109111</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14525"/>
    <dbReference type="EnsemblBacteria" id="AQP45873">
        <property type="protein sequence ID" value="AQP45873"/>
        <property type="gene ID" value="RPIT_14525"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06720">
        <property type="protein sequence ID" value="SDZ06720"/>
        <property type="gene ID" value="SAMN05428934_109111"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14525"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_3" evidence="1">
        <location>
            <begin position="80"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ06720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="285" mass="31135" checksum="5E44E1CC2B25661B" modified="2017-04-12" version="1">MRTFTVEMNPDREVTLEAILFDRALEYDGMPVVEDPRPAIIICPGGGYEMLSQREDNPAAVAFLRHGFNTFILRYSIREHASYPNPLVDAARAVRWVRAHAEDLGVDPASIAVMGFSAGGHVTAMLGTQWQNAELQAAERAEYEALAGRGVDANAGLMEHSSRPDAIIPSYAVFNFDWIPEESRLLHRAPTVDCIAGVSDSTPPAFVWTTGEDEIVPPSQSLRFVAAMAEAGVPFEYHHFAHGVHGLGVADPLSNADRATLPENAHAWVDLAARWLRATFEGNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CII9</accession>
    <name>A0A1Q2CII9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Long-chain acyl-CoA synthetase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Long-chain fatty acid--CoA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14480</name>
        <name evidence="3" type="ORF">SAMN05428934_109120</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14480"/>
    <dbReference type="EnsemblBacteria" id="AQP45865">
        <property type="protein sequence ID" value="AQP45865"/>
        <property type="gene ID" value="RPIT_14480"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06893">
        <property type="protein sequence ID" value="SDZ06893"/>
        <property type="gene ID" value="SAMN05428934_109120"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14480"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020459">
        <property type="entry name" value="AMP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00154">
        <property type="entry name" value="AMPBINDING"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="10"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ06893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="595" mass="65149" checksum="5F636E135F926E36" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIK3</accession>
    <name>A0A1Q2CIK3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bleomycin resistance protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_00250</name>
        <name evidence="5" type="ORF">SAMN05428934_1055</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bleomycin resistance protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY83513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00250"/>
    <dbReference type="EnsemblBacteria" id="AQP45934">
        <property type="protein sequence ID" value="AQP45934"/>
        <property type="gene ID" value="RPIT_00250"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY83513">
        <property type="protein sequence ID" value="SDY83513"/>
        <property type="gene ID" value="SAMN05428934_1055"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00250"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000335">
        <property type="entry name" value="Bleomycin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19581">
        <property type="entry name" value="Glyoxalase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="3">
        <location>
            <begin position="47"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY83513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="164" mass="18604" checksum="B64633951666993F" modified="2017-04-12" version="1">MNDQTHCNLCADVMWRAELRADINLELIAVAFGYKNWNTFVASEDAGPLTVPIIRTFPGPEADRFYLRFLGFSVDWEHRFEPSLPLYRQISRDGIVLHLSEHHGDATPGSAVRLRVADVATLQQQLLTSSIYPLRIGLESQEWGDELAIPDPFGNTLIFHTPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIN5</accession>
    <name>A0A1Q2CIN5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00240"/>
    <dbReference type="EnsemblBacteria" id="AQP45933">
        <property type="protein sequence ID" value="AQP45933"/>
        <property type="gene ID" value="RPIT_00240"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00240"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="111" mass="12295" checksum="9DE03801BD66DB43" modified="2017-04-12" version="1">MSNIIVERPKVVCLCGSLRFQRLFDSERKRLTARGIIVLAPEPVDEEPTASMRATLGELHLRRIDLADEVRVVSEGGYIGDATRREILYARATNKVVSAVEANVVLPTFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIU2</accession>
    <name>A0A1Q2CIU2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA (guanine-N(7)-)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA(m7G46)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trmB</name>
        <name evidence="2" type="ORF">RPIT_03430</name>
        <name evidence="3" type="ORF">SAMN05428934_101286</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; N(7)-methylguanine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03430"/>
    <dbReference type="EnsemblBacteria" id="AQP45993">
        <property type="protein sequence ID" value="AQP45993"/>
        <property type="gene ID" value="RPIT_03430"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30934">
        <property type="protein sequence ID" value="SDY30934"/>
        <property type="gene ID" value="SAMN05428934_101286"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03430"/>
    <dbReference type="UniPathway" id="UPA00989"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01057">
        <property type="entry name" value="tRNA_methyltr_TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417">
        <property type="entry name" value="PTHR23417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00091">
        <property type="entry name" value="TIGR00091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="196"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY30934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="222" mass="24353" checksum="08C994317FE9F738" modified="2017-04-12" version="1">MNESQQKNWDRLHSAFVVDIPRGDMSTSISDDASVDWAAEFGRDAPLIVEIGSGAGDSLVPMASQRPDANVVAFEVFEPAVASTLGRIGRAGISNVRVVVGDGAQGLAKLFADGTVSELWTFFADPWHKKRHHKRRLVAGDFADVVCAKLTPGGLWRLATDWEDYALWMREHLDDFPGLENVHGGWAPRLADRPVTKYEGKGLAAGRTVHDLTYRRTDAAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIV3</accession>
    <name>A0A1Q2CIV3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_03980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03980"/>
    <dbReference type="EnsemblBacteria" id="AQP46003">
        <property type="protein sequence ID" value="AQP46003"/>
        <property type="gene ID" value="RPIT_03980"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03980"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="60"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="253"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="335" mass="35923" checksum="EB03B07D43D1CF7A" modified="2017-04-12" version="1">MVPAASPTTHPKEPLVNESSVTLREVAELANRISAEMARVIEGKPQQIRTAVTVLLAGGHLLIEDVPGVGKTVLAKSLGRAIHGDVKRIQFTPDLLPSDVTGVSVFNQSTREFEFKPGGIFAHIVLGDEINRASPKTQSALLESMAEGQVSADGKTYALSKPFMVIATQNPIEMEGTYPLPEAQRDRFMARITMGYPARTSEIAMLTHHAGGDQLDTVTPVTDALAVAAAVEAIRAVYVAPVINDYIVTIVDKTRTHDDLRLGASPRASLHLMRAARVQAALAGRDYVIPEDVSALAVEVLAHRVLTTVEAQVARRDPDDIVRSIVASVPTPARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ31</accession>
    <name>A0A1Q2CJ31_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tryptophan synthase alpha chain</fullName>
            <ecNumber evidence="7">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">trpA</name>
        <name evidence="9" type="ORF">RPIT_06430</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the TrpA family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06430"/>
    <dbReference type="EnsemblBacteria" id="AQP46055">
        <property type="protein sequence ID" value="AQP46055"/>
        <property type="gene ID" value="RPIT_06430"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06430"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04724">
        <property type="entry name" value="Tryptophan_synthase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00131">
        <property type="entry name" value="Trp_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018204">
        <property type="entry name" value="Trp_synthase_alpha_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002028">
        <property type="entry name" value="Trp_synthase_suA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43406">
        <property type="entry name" value="PTHR43406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00290">
        <property type="entry name" value="Trp_syntA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00262">
        <property type="entry name" value="trpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00167">
        <property type="entry name" value="TRP_SYNTHASE_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP46055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="273" mass="28239" checksum="CE6760176B69B936" modified="2017-04-12" version="1">MGRSGQLVSDLLDQGRPALVAYLPVGYPSVEDSLKAVTAVVEGTDGRGADIVEIGIPYSDPLMDGLVIQHATAKARARGVRTRDAFRAVEAAAAAGATPMVMSYWNLIEAYGAEAFARDLAAAGGAGVITPDLPPDDCPEWFAATDGYELDRVFLIAPSSTDERIELTMSSCRGWVYASSVMGVTGARAATSDAAPVITERARSIDPGLPVGIGLGVSTGDQAAEIGSFADLVIVGSALLNCLASDGLDLQSDLIALRKLADDLADGVARARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ44</accession>
    <name>A0A1Q2CJ44_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07195"/>
    <dbReference type="EnsemblBacteria" id="AQP46070">
        <property type="protein sequence ID" value="AQP46070"/>
        <property type="gene ID" value="RPIT_07195"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07195"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="185" mass="20929" checksum="ED12FEA76C751C35" modified="2017-04-12" version="1">MRLSEIRTERLLLRRWRDSDRVPFAAMNADPEVMRYFPATLSRAESDQLIDRIEERFDQQGFGLWALELLESGQFIGFTGLNPMPDGVPGSGDQEVGWRLDRGAWHRGYATEAARAALDVGLTRLGLPVVWSMTAVLNLPSQAVMQRLGMTLHRYFDHPRIGVGHPLRPHVVYRSAGLTPPRPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ45</accession>
    <name>A0A1Q2CJ45_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribosomal protein S18 acetylase RimI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11345</name>
        <name evidence="3" type="ORF">SAMN05428934_10234</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY49039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP46137">
        <property type="protein sequence ID" value="AQP46137"/>
        <property type="gene ID" value="RPIT_11345"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY49039">
        <property type="protein sequence ID" value="SDY49039"/>
        <property type="gene ID" value="SAMN05428934_10234"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11345"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY49039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="156" mass="16965" checksum="136F41D415E12342" modified="2017-04-12" version="1">MGQATIRRVAPSDPDVATLLDEYFSDRAATWAGEGLGYQRRPANLSEGVILLVDVDGSTAGIGGLRHVPSDSGSWWEVKHMYIRPAARRSGLGRALIDALEAEARRLGATDLVLDTHHSLVAAVSLYEGAGFRATEAFNDNPNATRWFRKPLLPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ65</accession>
    <name>A0A1Q2CJ65_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_14200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14200"/>
    <dbReference type="EnsemblBacteria" id="AQP46188">
        <property type="protein sequence ID" value="AQP46188"/>
        <property type="gene ID" value="RPIT_14200"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14200"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="280"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="337"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="379"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP46188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="435" mass="46028" checksum="588610D585A8C306" modified="2017-04-12" version="1">MGWIVWGVGLFAYGVAVMHRTSLGVAGLEAADHFGTTPGIVSTFVVLQLATYALAQVPVGLVLDRVGSRVMVVAGSLIMGGSQALLAVSDDLPLAYAARVLLGIGDACIFNSVLRLLPRWFRPQLVPLLSQVTGMSASFGQIAAVAALLPLVKSGGWEYGLLIAAAVSLLPATAAAIWIRNAPPGTEPGVVSDRLREIPSNVLGVTKHPATQLGFWIHFTSGFSFTAFVFMWGLPYLVVGQGLSQAAAGGLLSLLAVSAMVAGPIIGTLTSRHPLRRSDLALIVIGAIILAWAVVLLWPGRAPLPLLILLVVVLSAGGPGTGIGFDFPRTNLPLTRLGAANGVVITGSFSGATLLILVMGVFLDLVADGRPYTPDHLRWAWALQAPFFLVGLAGILASRRRLRRLMAEQGVVVPSWREVVERIRRRRGRPGRRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ68</accession>
    <name>A0A1Q2CJ68_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11760"/>
    <dbReference type="EnsemblBacteria" id="AQP46144">
        <property type="protein sequence ID" value="AQP46144"/>
        <property type="gene ID" value="RPIT_11760"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11760"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="PTHR19353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FA_desaturase" evidence="1">
        <location>
            <begin position="87"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="407" mass="46204" checksum="7BED1E8516C5CCAC" modified="2017-04-12" version="1">MTTTTPQARADVSSSGKANPIAHLSPADIEAIGRELDELRDEVLASRGASDAAYIRKVIRTQRILEAGSRIVLLFSKFPPAFFGGTAGLTVAKIIENTEIGHNILHGQWDWMRDDKIHSSTWEWDFASPAEQWKRSHNVEHHTYTNVVGMDNDLGYNILRVDPDQEWEFKHVFQPVTNFFTALFFEYGIAAYDLKLKEWKDGSHPHEEFMADLKVVLAKMRKQMTKDYLVHPLLSGTSALSTLAANAIANTLRNVWTHSVIFCGHFPEGVETFETESIEGETRGEWYVRQMLGSANISGSKLMHIMTGNLSHQIEHHLFPDLPSNRYSQIAPRIRDLMERHGLRYVTGPLPVQVASAWRKVFRYSLPNKRDGVSQWREVAETAREAIGEAVRNTRGMWRPRRAAVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ96</accession>
    <name>A0A1Q2CJ96_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fido domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_13685</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13685"/>
    <dbReference type="EnsemblBacteria" id="AQP46174">
        <property type="protein sequence ID" value="AQP46174"/>
        <property type="gene ID" value="RPIT_13685"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13685"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="PTHR13504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="3">
        <location>
            <begin position="138"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="226"/>
            <end position="233"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="264"/>
            <end position="265"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP46174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="402" mass="43578" checksum="2F8A615D1893E3C3" modified="2017-04-12" version="1">MRLSWDNVVRAPTVPASPTDRSRLSVVGKPYRAAVPAAIKRMQFNIMPDVAALADDARAAITRFDAELSAMFDGEFAPLSAVLLRTESASSSQIENITVSARALSLANVGLAKFGSNAKLVQANVEAMNRALELTGPLTPGLILAVHEALMHGQDQAEPGRFRNQQVWIGGTDYSPHSADFVPPLNSRVHDSIGDLCAFSERTDLPLLAQAAIAHAQFETIHPFNDGNGRAGRALIHVMLRNGGASTRTTVPVSAGLLSNIDAYYEALTVYRDGDPNPIIDQISRAAFLAVDNGQQLATDLRTIHDGWATNLRARRDAVAWRVLPFLLRQPSVTSKLVQETFNVTQPAADNALRQLQEAGAVSKPKTIHGEGQKRNVVWQATEVLDALDRFGERARRSSRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJB3</accession>
    <name>A0A1Q2CJB3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_11250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP46135">
        <property type="protein sequence ID" value="AQP46135"/>
        <property type="gene ID" value="RPIT_11250"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11250"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP46135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="132" mass="14549" checksum="B51C733574C0983B" modified="2017-04-12" version="1">MIDLTLALQLRDAGLQWQPRSGDRFVVTSAELVDDVFHLADMVIEARELESGTIFAFNGTTEWALDSIAQEKTVWLPDEGQLRTALGRHFRSLSRDDAGFVVSLDDGAEFADRDPENAYARALLATLAHTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJE2</accession>
    <name>A0A1Q2CJE2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9 10">Chromosomal replication initiator protein DnaA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dnaA</name>
        <name evidence="15" type="ORF">RPIT_13605</name>
        <name evidence="16" type="ORF">SAMN05428934_11178</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1T</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1</strain>
        </source>
    </reference>
    <reference evidence="15" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 11">Belongs to the DnaA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ13014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13605"/>
    <dbReference type="EnsemblBacteria" id="AQP46170">
        <property type="protein sequence ID" value="AQP46170"/>
        <property type="gene ID" value="RPIT_13605"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ13014">
        <property type="protein sequence ID" value="SDZ13014"/>
        <property type="gene ID" value="SAMN05428934_11178"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13605"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06571">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1750.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00377">
        <property type="entry name" value="DnaA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001957">
        <property type="entry name" value="Chromosome_initiator_DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020591">
        <property type="entry name" value="Chromosome_initiator_DnaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018312">
        <property type="entry name" value="Chromosome_initiator_DnaA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013317">
        <property type="entry name" value="DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013159">
        <property type="entry name" value="DnaA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30050:SF2">
        <property type="entry name" value="PTHR30050:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00308">
        <property type="entry name" value="Bac_DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08299">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00051">
        <property type="entry name" value="DNAA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00760">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00362">
        <property type="entry name" value="DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01008">
        <property type="entry name" value="DNAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="13">
        <location>
            <begin position="142"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_DnaA_C" evidence="14">
        <location>
            <begin position="353"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="150"/>
            <end position="157"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="AQP46170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="SDZ13014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="446" mass="49789" checksum="3DDF30BA008730C7" modified="2017-04-12" version="1">MPDLTVLWDDVIAAADVPSRAWLRRTHPFDMHGSTVMLAVGDETTRERIETKLRAQIEDRLSVLRGQPTHLAVMINPELVPEPAIVSPAPVSDDAPATVSPRSRPQDVRLNPRYTFESFVAGSSNRFAHAAAAAVAETPGKSYNPLMIYGPSGLGKTHLLHAIGHYVTSYYEQLRVKYVSTEELTNDFINAISSNRTAEFRSSYRDVDVLLVDDIQFLESKIQTQEEFFHTFNTLHNAQKQIVMTSDRPPKLLEALEPRLRSRFEWGLMTDIQPPDLETRIAILRKKVASQRLTAGTQVLELIASRIPTNIRELEGALTRVAALASLNQQEITVPLAEQVLNDLMPDDATPVDAQTIMETSAKYFSITMDDLTGASRVATIASARQIAMYLCRELTDLSLPKIGHKFGGRDHSTVLHAVRKINEKIGVDRDLFNQVTELTNQIKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBP0</accession>
    <name>A0A1Q2CBP0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">D-methionine transport system permease protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Metal ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_00720</name>
        <name evidence="7" type="ORF">SAMN05428934_10597</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00720"/>
    <dbReference type="EnsemblBacteria" id="AQP43522">
        <property type="protein sequence ID" value="AQP43522"/>
        <property type="gene ID" value="RPIT_00720"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86008">
        <property type="protein sequence ID" value="SDY86008"/>
        <property type="gene ID" value="SAMN05428934_10597"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00720"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="21"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY86008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="226" mass="23867" checksum="7F0C2DE5342D4362" modified="2017-04-12" version="1">MILLDTWLNNPALQKALLPAIWETLQMVGISSVATVLLGLPLGVVLYTTAKGGLGENRALNAVLSGVVVNITRSIPYAILMLALIPVTRWLVGTSLGPLAASVSLAIAAIPFFARLVETALRDVHSGKLDAAHAMGSTKMQSVTKVLIPEAMPGIVAGITTTVVTIIGYSAMAGLIGGGGLGRLAYNYGFQRYELDVMAITIVVIVVMVQLVQWVGDLIARRVDHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBP6</accession>
    <name>A0A1Q2CBP6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lycopene beta-cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00795</name>
        <name evidence="2" type="ORF">SAMN05428934_105112</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00795"/>
    <dbReference type="EnsemblBacteria" id="AQP43534">
        <property type="protein sequence ID" value="AQP43534"/>
        <property type="gene ID" value="RPIT_00795"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86397">
        <property type="protein sequence ID" value="SDY86397"/>
        <property type="gene ID" value="SAMN05428934_105112"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00795"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY86397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="373" mass="39569" checksum="A710168F2D123356" modified="2017-04-12" version="1">MSSSFDVAVVGLGPAGRALASACLVRGMRVLAVDPRIEGRWTPTYGIWGDELGALPESVIRERVVHPELRAHGRYPLRRDYLVLDNAALQAALPLAGAELRQARLTDDDVTALLSEARVVVDARGARPNGSRPDDPAPAQTAYGIVVEAAAAAPALDGAAGLLMDWRTDWADDDAPAPPTFLYAIPVGNGRILLEETCLAAAPGLPIEELKRRLRRRLLHRGVAPDAIDHPLEREVVRIPMRGRGEPAPAGVLAVGTAGRGGNIVTGYSVAHALKRAETLADELAAGRALRSADPIGPTDLFREMGLRALLRLDTPGTLALFEAFGRIPTASQREFMSRDASAAGLARAMWGMFVRMPVRAKGALVAATLGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBR8</accession>
    <name>A0A1Q2CBR8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sugar phosphate isomerase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Sugar phosphate isomerase/epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00905</name>
        <name evidence="3" type="ORF">SAMN05428934_105133</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00905"/>
    <dbReference type="EnsemblBacteria" id="AQP43556">
        <property type="protein sequence ID" value="AQP43556"/>
        <property type="gene ID" value="RPIT_00905"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86972">
        <property type="protein sequence ID" value="SDY86972"/>
        <property type="gene ID" value="SAMN05428934_105133"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00905"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="20"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY86972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="334" mass="36559" checksum="F19B10473EC16AC0" modified="2017-04-12" version="1">MKLGVYNAVLHDRPLEDALAVIADLGLTGIEINSGGFLPPTHIPEIDEIVASPAAAKKYLARFDGTGVEIAGLNCNGNPLHPNRSIGDKHADDIRRSIRAAAALGQDRVVTMSGLPGGEPGVRHPNWIVNAWNSAALDVLDYQWEVAAAFWSEMDQFAKDHGVKVALELHPQNLVFNARDVRKLIELTGATHLGVEMDASHLFWQQADPIAVVRELGPLILHAAAKDVRINPEHARLNGVLDNGFRRLAPDEDRVNLGGDEWANEWPKDSSWDFVALGKGHDTAYWTEFIRALHEVDPDMCLNIEHEDTELGRIEGLEVAATVLTDAWAAFAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBS4</accession>
    <name>A0A1Q2CBS4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00925</name>
        <name evidence="4" type="ORF">SAMN05428934_105137</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00925"/>
    <dbReference type="EnsemblBacteria" id="AQP43559">
        <property type="protein sequence ID" value="AQP43559"/>
        <property type="gene ID" value="RPIT_00925"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87076">
        <property type="protein sequence ID" value="SDY87076"/>
        <property type="gene ID" value="SAMN05428934_105137"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00925"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="2">
        <location>
            <begin position="59"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="246"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY87076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="306" mass="34497" checksum="3CDE28B1F618BAF2" modified="2017-04-12" version="1">MTWREMMLDQLEFYWNVHLWPRLEGLTDDEYWWEPVPGCWSLRRDAEGELKHEFFTVDPPVPPVTTIAWRIVHIGRDVLGTRARAFFGDRSLPEGALPTEDLAMYDARWWPEPLPATADEALAFLDKTYTMWCDGIRSLDDDALLRPLGPRGDHHADQSWGALVLHINREVMAHGAEVSLLRDLYRAQRDQEDPVVGAARRDDAAEVARLMDEGVEVPPLLLSEESGRRHWDVVRALVEHGAVDGGNPSALHYAAAAGELGTVRLLLDHGADREMTDAQFGMAPAVWAEHFGHADVAAYLRGMPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBU1</accession>
    <name>A0A1Q2CBU1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytidylate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00985</name>
        <name evidence="2" type="ORF">SAMN05428934_105148</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00985"/>
    <dbReference type="EnsemblBacteria" id="AQP43570">
        <property type="protein sequence ID" value="AQP43570"/>
        <property type="gene ID" value="RPIT_00985"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87377">
        <property type="protein sequence ID" value="SDY87377"/>
        <property type="gene ID" value="SAMN05428934_105148"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00985"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY87377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="217" mass="24789" checksum="AEA6851584352DE3" modified="2017-04-12" version="1">MSAITVSRKLGSYGGRIAERVARELGWKFADRFFIDAVISEYGLIEMDELYDKPPTLLDLFNENTAMTIQWMNKTVKTLAAKYDVVILGRGGFAALKGYSDVFNVLVTAPEELRVQRVMEDNKVSTGVAREMVERDVDTKKRFVRRYYGEDWAAEDSYDLVVDTSEVSEDEAVQRIIDAARGWFEKSDGPRIGGLEVDEMLLHTIEERFNTDTTLYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBV9</accession>
    <name>A0A1Q2CBV9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_01135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43596">
        <property type="protein sequence ID" value="AQP43596"/>
        <property type="gene ID" value="RPIT_01135"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01135"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="178" mass="20030" checksum="A47C4F5544D87044" modified="2017-04-12" version="1">MVSFGNLLAQRLLELWAQGETLDNEHLRQVVSDVALISGKTQLTVVANHVVADEVPTEASKYHFVDSYLGVAEYKDSRLEQVTQLIQRCVYLRVGWPQILELQAEARALFGAPDLASVLWQAGLLGVEEEDDGLAHFFTMDRLGRLRLPRGLDRYVFHPSLREVCGLLPSGGPIYWRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBY5</accession>
    <name>A0A1Q2CBY5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_01240</name>
        <name evidence="11" type="ORF">SAMN05428934_105197</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY88604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01240"/>
    <dbReference type="EnsemblBacteria" id="AQP43610">
        <property type="protein sequence ID" value="AQP43610"/>
        <property type="gene ID" value="RPIT_01240"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY88604">
        <property type="protein sequence ID" value="SDY88604"/>
        <property type="gene ID" value="SAMN05428934_105197"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01240"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00164">
        <property type="entry name" value="ABC2TRNSPORT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="9">
        <location>
            <begin position="35"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP43610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY88604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="274" mass="29692" checksum="52447BEBF8BD0E06" modified="2017-04-12" version="1">MSTGVIDSGLSADHRVSARWGWWSLVEHRAKLIRYYYPTMLITGIGSPFLYLLGLGYGLGVLVDQGRGIEGVPYLTFVAPALVMATVMQVSAQENTFGVFGGFKWSNTFTAMRLTPVTPGQMAVGYQASVLVRVSIMLGFYLVALLIFGIGRPLGVLLLFPIGILLSIAVGFAVMAWVATQKDDRGQLSFVERFVIVPLTLFSGTYFPLDTLPGYLQPIGWISPLWHAAELGRAALYGAPLSAVMAAVHVGFLVLVALVAAALSTRTFRRRLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC17</accession>
    <name>A0A1Q2CC17_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphohistidine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_01520</name>
        <name evidence="2" type="ORF">SAMN05428934_10852</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01520"/>
    <dbReference type="EnsemblBacteria" id="AQP43654">
        <property type="protein sequence ID" value="AQP43654"/>
        <property type="gene ID" value="RPIT_01520"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01924">
        <property type="protein sequence ID" value="SDZ01924"/>
        <property type="gene ID" value="SAMN05428934_10852"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01520"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ01924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="166" mass="18244" checksum="DEC1191AB81A3B58" modified="2017-04-12" version="1">MRRLVLMRHAKTEANHVEGDKARRLNPRGVQDAQEAGVALRGLGVDYALVSSAVRTRETFAHLGLDVPVEFQDALYYGGTETMLQRIAEMGDDVECLLVVGHAPTVPSLVAELAYASNRAEADQAQCWFPTAAYTVFSFDGSWESLGEGDLDHVHLDAVTRPDKHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC73</accession>
    <name>A0A1Q2CC73_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_01525</name>
        <name evidence="2" type="ORF">SAMN05428934_10853</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01525"/>
    <dbReference type="EnsemblBacteria" id="AQP43655">
        <property type="protein sequence ID" value="AQP43655"/>
        <property type="gene ID" value="RPIT_01525"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01943">
        <property type="protein sequence ID" value="SDZ01943"/>
        <property type="gene ID" value="SAMN05428934_10853"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01525"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ01943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="334" mass="36342" checksum="1CDB885C4FB08962" modified="2017-04-12" version="1">MPRYLMLRSPSANRVYAGESGPLTAAELQLTAPFASEVADAELAGVSYLGFDAPALSDANLETVARQSACFALFEAEGELLRPVALPQPFTLDDDLITIPKYPGKTNEQFTQLLVNVTLSAVTREPTGPRQILDPLAGRGTTLSTALLLGHDGFGVEGDAKAFEQMVSYYKTYLRRKRIKHTADVTPVRREGKAIGKRFDAEISTDDARHRVTAFTGDTRQSAELFGKKRFDAIITDAPYGVAHGSTTDVRGVSGKRDRSPAGLLREALPVWAGQLMHGGALGLSWNTFGLSREDLAQMLADAGLRVREGDAWERFAHRVDSSIRRDLIVAVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCA3</accession>
    <name>A0A1Q2CCA3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aspartate ammonia-lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">aspA</name>
        <name evidence="3" type="ORF">RPIT_02050</name>
        <name evidence="4" type="ORF">SAMN05428934_1017</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY22510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02050"/>
    <dbReference type="EnsemblBacteria" id="AQP43742">
        <property type="protein sequence ID" value="AQP43742"/>
        <property type="gene ID" value="RPIT_02050"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY22510">
        <property type="protein sequence ID" value="SDY22510"/>
        <property type="gene ID" value="SAMN05428934_1017"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02050"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="1">
        <location>
            <begin position="9"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="FumaraseC_C" evidence="2">
        <location>
            <begin position="407"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY22510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="492" mass="53448" checksum="1140B3465AFF5799" modified="2017-04-12" version="1">MRIERDSLGEMSIPDDAYWGINTARAMENFAISRRTISVYPDLLIAYAQVKQAAARANNELGVLDDERAGLIDRACQDIIDGELHEQFVVSVIQGGAGTSTNMNVNEVIANRALDLAGRPFGDYEFISPNDHVNKSQSTNDTYPSAVKLSVAYGVYGLMQEMRLLRNSFSQKGREFRDVLKVGRTQLQDAVPMTLGQEFRGFGTTIGEDVDRLEDVREMLLELNLGATAIGTGIAASKGFGEAVMRHLREITGYEELRQAADLIEATSDTGVFMSVSSAMKRAAMKLSKICNDLRLLSSGPQTGLGEINLPAVQAGSSIMPGKVNPVIPEAVNQVAFIIAGADVTISMASESGQLQLNAFEPVMAHVLLQNSTWLRRAVRTLRINCVDGITANEERLRSQVDQSVGVVTALMPQLGYLNAAKLAKEALKGGTSIRDLVLDRGLLSESEVERALEPSGLSGGIFDTGPMPRMTPELIAEMEKRLDEADRHNEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCD5</accession>
    <name>A0A1Q2CCD5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase and inactivated derivatives</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_02265</name>
        <name evidence="2" type="ORF">SAMN05428934_10152</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY23850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43783">
        <property type="protein sequence ID" value="AQP43783"/>
        <property type="gene ID" value="RPIT_02265"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY23850">
        <property type="protein sequence ID" value="SDY23850"/>
        <property type="gene ID" value="SAMN05428934_10152"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02265"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002514">
        <property type="entry name" value="Transposase_8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01527">
        <property type="entry name" value="HTH_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY23850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="96" mass="10860" checksum="4A15240413D673C4" modified="2017-04-12" version="1">MSSKRRKFTPEFKADAVQLVVVAQRPIAQVARELEINESSLGYWVKLYRKQHPDPVKAPPPVEAARLAALEAEVRRLSEENAFLKKAAAFFARTQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCG5</accession>
    <name>A0A1Q2CCG5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_02320</name>
        <name evidence="2" type="ORF">SAMN05428934_10164</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY24206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02320"/>
    <dbReference type="EnsemblBacteria" id="AQP43794">
        <property type="protein sequence ID" value="AQP43794"/>
        <property type="gene ID" value="RPIT_02320"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY24206">
        <property type="protein sequence ID" value="SDY24206"/>
        <property type="gene ID" value="SAMN05428934_10164"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02320"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY24206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="76" mass="8488" checksum="9046AFB9A4101FBD" modified="2017-04-12" version="1">MAKVTDVVGLYLNPPENAVVLCVDEKSQIQALNRTQKVLPMQPGHNEQRSHDYVRHGTTTLFAALEIATVSQRTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCI8</accession>
    <name>A0A1Q2CCI8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tetratricopeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_02435</name>
        <name evidence="5" type="ORF">SAMN05428934_10185</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY24849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02435"/>
    <dbReference type="EnsemblBacteria" id="AQP43816">
        <property type="protein sequence ID" value="AQP43816"/>
        <property type="gene ID" value="RPIT_02435"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY24849">
        <property type="protein sequence ID" value="SDY24849"/>
        <property type="gene ID" value="SAMN05428934_10185"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02435"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="2"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
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            <end position="129"/>
        </location>
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            <begin position="171"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="79"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY24849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="267" mass="28340" checksum="1374C8A4E97FB33B" modified="2017-04-12" version="1">METDDGMRFGASDQVGGPVPSAAPNDNDAEILHFLESAPPSVRDWAAARAAEIRAAAGPAPAPARPAADDPADLALAELGEHDDEPRRRPLVHTPRDKEPTYVAPQRRSSPLVPLVGLLVVVALVYGIFQLGRPQETADPGMNTAAPANAADTTSRMAELEEMLAEAPDDVAVNLELGVLKFNAGDIPRAEELWTKVTDVDPRNPQAWFNLGFVHLAQDPPDVEGARADWEQVLEVAPESDLAATVESHLAALEAPSAAPSPSQTQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCJ6</accession>
    <name>A0A1Q2CCJ6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">1,4-dihydroxy-2-naphthoate octaprenyltransferase</fullName>
            <shortName evidence="6">DHNA-octaprenyltransferase</shortName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">menA</name>
        <name evidence="7" type="ORF">RPIT_02575</name>
        <name evidence="8" type="ORF">SAMN05428934_101115</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>1,4-dihydroxy-2-naphthoate + an all-trans-polyprenyl diphosphate + H(+) = a 2-demethylmenaquinol + CO2 + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:26478"/>
            <dbReference type="Rhea" id="RHEA-COMP:9563"/>
            <dbReference type="Rhea" id="RHEA-COMP:9564"/>
            <dbReference type="ChEBI" id="CHEBI:11173"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:55437"/>
            <dbReference type="ChEBI" id="CHEBI:58914"/>
            <dbReference type="EC" id="2.5.1.74"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Quinol/quinone metabolism; menaquinone biosynthesis; menaquinol from 1,4-dihydroxy-2-naphthoate: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MenA family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.74" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY25714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02575"/>
    <dbReference type="EnsemblBacteria" id="AQP43838">
        <property type="protein sequence ID" value="AQP43838"/>
        <property type="gene ID" value="RPIT_02575"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY25714">
        <property type="protein sequence ID" value="SDY25714"/>
        <property type="gene ID" value="SAMN05428934_101115"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02575"/>
    <dbReference type="UniPathway" id="UPA00079">
        <property type="reaction ID" value="UER00168"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046428">
        <property type="term" value="F:1,4-dihydroxy-2-naphthoate octaprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13962">
        <property type="entry name" value="PT_UbiA_UBIAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01937">
        <property type="entry name" value="MenA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004657">
        <property type="entry name" value="MenA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026046">
        <property type="entry name" value="UBIAD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13929">
        <property type="entry name" value="PTHR13929"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005355">
        <property type="entry name" value="UBIAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY25714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="292" mass="29780" checksum="9F8AC58E772A33D8" modified="2017-04-12" version="1">MENSPAIWAVGARPRTLPAAVAPVIAGVASAATVDEYHWWVALGCLVVALALQVGVNYANDYSDGVRGTDDERVGPTRLVASGLASPRAVKTAAFLSFGVAAVAGLAVVALSGHWWLLGVGALSVLAAWYYTGGAKPYGYLGLGELMVFIFFGLVATVGTTYVIAGTAPAQAWLAATAVGVLASGILVANNLRDIATDSVVGKMTLPVRLGDRNTRLFYAALCAVAALAVVGYAALTSWWALLGLLGVVLILPGLKLVLGGATGRDLIPVIQSTGMAEVALSMGLLAAAFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCK2</accession>
    <name>A0A1Q2CCK2_9ACTN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="AQP43827"/>
        <property type="gene ID" value="RPIT_02510"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02510"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="72" mass="8466" checksum="F72C0706578C0CC9" modified="2017-04-12" version="1">MKTAAWANWSRPKDVALQRSPADPERYYAYYGTWSAMARMQDFAPYSTTPRAAERWDEDADDDEARDSRGWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCM3</accession>
    <name>A0A1Q2CCM3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmG</name>
        <name evidence="5" type="ORF">RPIT_02800</name>
        <name evidence="6" type="ORF">SAMN05428934_101160</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY26973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02800"/>
    <dbReference type="EnsemblBacteria" id="AQP43873">
        <property type="protein sequence ID" value="AQP43873"/>
        <property type="gene ID" value="RPIT_02800"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY26973">
        <property type="protein sequence ID" value="SDY26973"/>
        <property type="gene ID" value="SAMN05428934_101160"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02800"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00294">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038584">
        <property type="entry name" value="L33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001705">
        <property type="entry name" value="Ribosomal_L33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018264">
        <property type="entry name" value="Ribosomal_L33_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43168">
        <property type="entry name" value="PTHR43168"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01023">
        <property type="entry name" value="rpmG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00582">
        <property type="entry name" value="RIBOSOMAL_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY26973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="56" mass="6800" checksum="1E72B7A0A60B877C" modified="2017-04-12" version="1">MAKKSQDVRPKITLACTECKERNYITKKNRRNDPDRLELKKFCPRCRTHQAHRETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCM5</accession>
    <name>A0A1Q2CCM5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha-1,6-mannosyltransferase/alpha-1,6-mannosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02755</name>
        <name evidence="3" type="ORF">SAMN05428934_101151</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY26779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02755"/>
    <dbReference type="EnsemblBacteria" id="AQP43868">
        <property type="protein sequence ID" value="AQP43868"/>
        <property type="gene ID" value="RPIT_02755"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY26779">
        <property type="protein sequence ID" value="SDY26779"/>
        <property type="gene ID" value="SAMN05428934_101151"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02755"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="401"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="435"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="458"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY26779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="499" mass="54328" checksum="CBDEEEDA8F6EFF8E" modified="2017-04-12" version="1">MRSLASEVVRGLAQAGRTRAVWTGFLGSVGILIGSLSPAYLPQASPVWDTLRTFGIDGPTTRWIGTIATLVGLALLLESWFRLRPSRRRARGRPQLRHWAVLAIVSAPLLLGPPIFSHDAYSYAAHGWLIHNNLSPYQVGPGILPGYYADQVAWVWRETTAPYGPLSLWLSHGIVQAAGFDPFVSALLMRLPALAGVILIGILVPAIARRVGADPAAASWFAVLNPILVIDFIGGAHNDSQMTGLMLLGIWLTMRYRAWWLGALVIGVAAAIKQPAFLAAVALPFLVTPWSSWRPRPFTIAMFRALGSLGLSVAVFAAISLGSGLGFGWVNAINVPGMVDTVSPFTVLGHLVQFPFNLASGDMTGRGWVTTFRGIGAAAAVLGMIYFAVRHLGQRPLTFISWSLIWFALCAPAIHSWYLLWGAVLLPMTHPSQRLLRGAIVATVVLLGFNAMNFGLRNGWWMLVLLLFGATYWIMHSHELSQPMDPDEPAPELAQDQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCM9</accession>
    <name>A0A1Q2CCM9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH-quinone oxidoreductase subunit K</fullName>
            <ecNumber evidence="5">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">NADH dehydrogenase I subunit K</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NDH-1 subunit K</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nuoK</name>
        <name evidence="6" type="ORF">RPIT_02680</name>
        <name evidence="7" type="ORF">SAMN05428934_101136</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the complex I subunit 4L family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY26369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02680"/>
    <dbReference type="EnsemblBacteria" id="AQP43856">
        <property type="protein sequence ID" value="AQP43856"/>
        <property type="gene ID" value="RPIT_02680"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY26369">
        <property type="protein sequence ID" value="SDY26369"/>
        <property type="gene ID" value="SAMN05428934_101136"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02680"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01456">
        <property type="entry name" value="NDH1_NuoK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001133">
        <property type="entry name" value="NADH_UbQ_OxRdtase_chain4L/K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039428">
        <property type="entry name" value="NUOK/Mnh_C1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11434">
        <property type="entry name" value="PTHR11434"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00420">
        <property type="entry name" value="Oxidored_q2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0874">Quinone</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY26369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="99" mass="10716" checksum="9E02517CB0829691" modified="2017-04-12" version="1">MSPEGYLILSAILFTVGVAGFLLRRNAIIAFMSIELMLNATNLAFVSFSRYHGNLDGLIAAFFVMVVAAAEVVVGLAIIVAVYRARRSASVDDVNLMKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCQ5</accession>
    <name>A0A1Q2CCQ5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02940</name>
        <name evidence="3" type="ORF">SAMN05428934_101189</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY27892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02940"/>
    <dbReference type="EnsemblBacteria" id="AQP43898">
        <property type="protein sequence ID" value="AQP43898"/>
        <property type="gene ID" value="RPIT_02940"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY27892">
        <property type="protein sequence ID" value="SDY27892"/>
        <property type="gene ID" value="SAMN05428934_101189"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02940"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY27892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="387" mass="39029" checksum="D5215869C206BD1A" modified="2017-04-12" version="1">MIIPSDEPVPARDRTRERLYYLIRSGAATSRSALVEATGLSRSTVNSAVTGLIRTGRVVEAGEEPKGVGSGSGRPATTLRAAPGEAIVGAIDFGHDRIAVALGDGTGQCIAEDSVDTDVDLRAHEAMDQACELLIGLAGTLGIGAPSAVAAGIPGPLDSRTGLVCSATILSSWVGLNPAEELSRRLGTAAHAENDALLGALGEQRLGAGRGHSNVFYIRATAGLGAGLILDGRLYRGATGIAGEIGHTAVPGGGGGEPCRCGRRGCLETVVSVGAVLQRIRHSHPGVAPDEITVSQPADAVTARIMAEVGATLGDALAMFCNLLNPSVLVLGGELGASGPSFVDSVRMSLLREAQPATGAGLDVVPAGLGVRAELVGALQAAAELVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCT2</accession>
    <name>A0A1Q2CCT2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter substrate-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Amino acid ABC transporter substrate-binding protein, PAAT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_02900</name>
        <name evidence="6" type="ORF">SAMN05428934_101181</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY27643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02900"/>
    <dbReference type="EnsemblBacteria" id="AQP43890">
        <property type="protein sequence ID" value="AQP43890"/>
        <property type="gene ID" value="RPIT_02900"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY27643">
        <property type="protein sequence ID" value="SDY27643"/>
        <property type="gene ID" value="SAMN05428934_101181"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02900"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544429" evidence="3">
        <location>
            <begin position="27"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="4">
        <location>
            <begin position="63"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY27643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="302" mass="31680" checksum="27F06AA5EEC5CD9C" modified="2017-04-12" version="1">MRRLVATGLLAALALTACGQDSSTPADSSAPADSTDRTYDVSGVEKVDAIAALVPSSISEKGTLTVGASTDYAPAEFRAEDLQTAIGYDVDLSKALGRVLGLEAEVVDAEFASILPSIGTKFDLGISSFTITEERTANYNMISYITVGSSYAVKSGNPDEFNPDDVCGETIAVQTGTWQDEELASFSQQCTDEGKEAIEVLQYGRQSDATTNVVGGKATAYYADSTVASYSAALTNGQLEVVGGIRDAAPQGIVVKGDDEEMTQAVQQAMQHLMDEGVWQEILDAWGIEDAALTTAEINPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCU7</accession>
    <name>A0A1Q2CCU7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5 7">50S ribosomal protein L16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplP</name>
        <name evidence="9" type="ORF">RPIT_03075</name>
        <name evidence="10" type="ORF">SAMN05428934_101216</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY28749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03075"/>
    <dbReference type="EnsemblBacteria" id="AQP43921">
        <property type="protein sequence ID" value="AQP43921"/>
        <property type="gene ID" value="RPIT_03075"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY28749">
        <property type="protein sequence ID" value="SDY28749"/>
        <property type="gene ID" value="SAMN05428934_101216"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03075"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01342">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_L10e/L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_L10e/L16_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020798">
        <property type="entry name" value="Ribosomal_L16_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="PTHR12220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="SSF54686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01164">
        <property type="entry name" value="rplP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00586">
        <property type="entry name" value="RIBOSOMAL_L16_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00701">
        <property type="entry name" value="RIBOSOMAL_L16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L16" evidence="8">
        <location>
            <begin position="4"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP43921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY28749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="139" mass="15785" checksum="A1E76434AB164296" modified="2017-04-12" version="1">MLIPRRVKFRKQHHPKRDGAAKGGTRLAFGEYGIQALESSYLTNRQIEAARIAMTRHIKRGGKVWINVYPDRPLTKKPAETRMGSGKGSPEWWVANIKPGRVLFELSGVPEDVAREAMRLAIHKLPFKARFIKREAGDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCY2</accession>
    <name>A0A1Q2CCY2_9ACTN</name>
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        <submittedName>
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        </submittedName>
        <submittedName>
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        </submittedName>
    </protein>
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    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
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            <taxon>Bacteria</taxon>
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    </organism>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03320"/>
    <dbReference type="EnsemblBacteria" id="AQP43964">
        <property type="protein sequence ID" value="AQP43964"/>
        <property type="gene ID" value="RPIT_03320"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30275">
        <property type="protein sequence ID" value="SDY30275"/>
        <property type="gene ID" value="SAMN05428934_101265"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03320"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
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        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="7"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="145"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY30275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="396" mass="42598" checksum="7DD4E42980927FC0" modified="2017-04-12" version="1">MSARTIGVGVVSLGWMGRLHARSYRALAEKFPHLGADVRLVAAADSNEATCAAALTEMGFERAYDDYRKLIADPDVDVVSICSPNFLHKEVALAAAAAGKPFWIEKPMGVSAAESRQIAEAVEDAGLVTAVGFNYRHVPAIEKARELIRSGRLGRIMNVRCWLIADYAASPEGPLTWRDSRERGGSGVIGDLMSHGADLVQYLVGRIESVTALTGQFITERPIPLKSGVGHFGYELSDEKGPVENEDYIALLGRLEGGALATLEASRVAIGPRAEYIVEVYGSDGSIRWNFEHLNDLQVCIGRDSEFLGYTRVMAGGDFPRFATFQPGAGTSMGFDDMKVVEAAKFIESVLTGRQLAPSVADGWSAAEIDEAALQSAADGRWHDVPEVTGAVTYNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD03</accession>
    <name>A0A1Q2CD03_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATPase components of ABC transporters with duplicated ATPase domains</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Glycerophosphodiester phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_03555</name>
        <name evidence="8" type="ORF">SAMN05428934_101312</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY31686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03555"/>
    <dbReference type="EnsemblBacteria" id="AQP44003">
        <property type="protein sequence ID" value="AQP44003"/>
        <property type="gene ID" value="RPIT_03555"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY31686">
        <property type="protein sequence ID" value="SDY31686"/>
        <property type="gene ID" value="SAMN05428934_101312"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03555"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="5"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="286"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="498"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="527"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
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        </ligand>
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        <location>
            <begin position="318"/>
            <end position="325"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY31686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="585" mass="64122" checksum="F7A89C330DB39EDC" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD06</accession>
    <name>A0A1Q2CD06_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Putative ABC transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_03390</name>
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    </gene>
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03390"/>
    <dbReference type="EnsemblBacteria" id="AQP43977">
        <property type="protein sequence ID" value="AQP43977"/>
        <property type="gene ID" value="RPIT_03390"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30679">
        <property type="protein sequence ID" value="SDY30679"/>
        <property type="gene ID" value="SAMN05428934_101278"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03390"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY30679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="300" mass="31207" checksum="5597D134E27775E0" modified="2017-04-12" version="1">MIIALEIGLLYAVMALGVYLTYRVLDFPDLTVDGSFVTGAATCVTLLVAGAPIAVAMAAATVAGALAGAITGLLHVWGKINPLLAGIITQIALYSINLRIMGRANLPVPRDLENLFTPIRQAGLWGTWVSVGIYALVIAVIGALVYWFLGTQYGVALRATGDNEMMARSQGINTGVSKTVGLMISNALVAFCGAILAQYNGYADISMGIGLIVAGLASVIVGQAIFGMTAVWQAVLAAALGSIVYRGVIQLALNAGFNPNDMKLISAVLVVAALILPAWGPVKRLRARRRRAAAVAEGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD46</accession>
    <name>A0A1Q2CD46_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Cytochrome c oxidase subunit 2</fullName>
            <ecNumber evidence="14">7.1.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">RPIT_03635</name>
        <name evidence="18" type="ORF">SAMN05428934_101328</name>
    </gene>
    <organism evidence="17 19">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 19" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">RP1T</strain>
        </source>
    </reference>
    <reference evidence="18 20" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">RP1</strain>
        </source>
    </reference>
    <reference evidence="17" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 14">Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 = 4 Fe(III)-[cytochrome c] + 4 H(+)(out) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11436"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="7.1.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="14">Binds a copper A center.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the cytochrome c oxidase subunit 2 family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.9" evidence="14"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY32193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03635"/>
    <dbReference type="EnsemblBacteria" id="AQP44017">
        <property type="protein sequence ID" value="AQP44017"/>
        <property type="gene ID" value="RPIT_03635"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY32193">
        <property type="protein sequence ID" value="SDY32193"/>
        <property type="gene ID" value="SAMN05428934_101328"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03635"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045187">
        <property type="entry name" value="CcO_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002429">
        <property type="entry name" value="CcO_II-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001505">
        <property type="entry name" value="Copper_CuA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014222">
        <property type="entry name" value="Cyt_c_oxidase_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011759">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036257">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22888">
        <property type="entry name" value="PTHR22888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00116">
        <property type="entry name" value="COX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02790">
        <property type="entry name" value="COX2_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81464">
        <property type="entry name" value="SSF81464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02866">
        <property type="entry name" value="CoxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00078">
        <property type="entry name" value="COX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50857">
        <property type="entry name" value="COX2_CUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0186">Copper</keyword>
    <keyword evidence="8 13" id="KW-0249">Electron transport</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 13 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="COX2_CUA" evidence="16">
        <location>
            <begin position="96"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="AQP44017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="SDY32193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="250" mass="27921" checksum="2BAF2687F89C3953" modified="2017-04-12" version="1">MFFGLPEAASEQAENVGDLWLGAWVASLVIGGLVWGLIGWAVVRYRNRNGDDAPPRQTTYHLPLELLYTLVPFLIIGVLFFYTVKTQDSVRNFEGEPDVEIGVIGQKWSWTFNYMEEGNPDVGTNAYTVGTLETIPELYLPVDKTIRFKLESADVIHSFWVPVFRDKLDVIPGHTNYLTVTPNKVGTYDGKCAELCGEFHSLMLFKVHVVSEEDYEAHVRGLAEGGNAGERQLQEALQAVLPTAAPEENQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD69</accession>
    <name>A0A1Q2CD69_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cell wall-associated hydrolase, NlpC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_03770</name>
        <name evidence="7" type="ORF">SAMN05428934_101356</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY32967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03770"/>
    <dbReference type="EnsemblBacteria" id="AQP44041">
        <property type="protein sequence ID" value="AQP44041"/>
        <property type="gene ID" value="RPIT_03770"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY32967">
        <property type="protein sequence ID" value="SDY32967"/>
        <property type="gene ID" value="SAMN05428934_101356"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03770"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544436" evidence="4">
        <location>
            <begin position="27"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="NlpC/P60" evidence="5">
        <location>
            <begin position="263"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="203"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="31"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="203"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="230"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY32967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="380" mass="40702" checksum="E2B220C0FF7CAE2A" modified="2017-04-12" version="1">MNRARLALASAVAAALLVTSGAVAQADPEAVERARQELASIQQQASAIDQEIIEASERAQDAEATLKHLSADLAAQEGKVATLTSELGDVATLQMHTDSISLTAQLLTSGSSDSFLSGLATMQSELNRANAGIQQLQLDQARLTTLREDAAAAEATLRAERDKAVALAEEFDAKEAEAERVYERLSEEERQRLAAIEAERQRIADEQQRQAEQQQREAEQREREAQAGSTSRSRDTASAQPSASATEAAKKDEPAPAAESGGSDRAQRAVQAALAQVGKRYVWGTSGPNTFDCSGLTSYAYRQVGINLTRSSRAQWSSVGRKVSKSELRPGDLVFYYSPVSHVGLYIGNGKIVDAANPRSGIRVTSLNSMPFTGARRVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDC2</accession>
    <name>A0A1Q2CDC2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amino acid ABC transporter membrane protein 2, PAAT family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Polar amino acid ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_04230</name>
        <name evidence="8" type="ORF">SAMN05428934_101450</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY35647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04230"/>
    <dbReference type="EnsemblBacteria" id="AQP44118">
        <property type="protein sequence ID" value="AQP44118"/>
        <property type="gene ID" value="RPIT_04230"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY35647">
        <property type="protein sequence ID" value="SDY35647"/>
        <property type="gene ID" value="SAMN05428934_101450"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04230"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="79"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY35647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="309" mass="33787" checksum="08BCAF91C6B3ECFA" modified="2017-04-12" version="1">MSASVLYDAPGPKTRARSRLISYISFTVIVGAFVWLIVALALPRTTVNGVVLTGVFSPERWEFALDVQFWRRLLIDGLLMGTLRVAALAAVLAVLIGVAFSFGRTARSVVIRVPVAIILELFRGMPVLLMMLFILLVMRTNGYWAAVWALAVYNGAIIGEALRSGIAALPRGQREAGLSLGLTPFKTRMLIEFPQAFRQMLPIIVAQLVVLLKDTSLAYIVAYPEILRISQQLRDFYGSTTVSFSLFTIVLVIYLAVNLALSAFARWLARRPASASSISQADAHAIDLVATGADVVTDEDKNPFGDGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDE9</accession>
    <name>A0A1Q2CDE9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_04350</name>
        <name evidence="6" type="ORF">SAMN05428934_101475</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY36262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04350"/>
    <dbReference type="EnsemblBacteria" id="AQP44139">
        <property type="protein sequence ID" value="AQP44139"/>
        <property type="gene ID" value="RPIT_04350"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY36262">
        <property type="protein sequence ID" value="SDY36262"/>
        <property type="gene ID" value="SAMN05428934_101475"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04350"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
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    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="4">
        <location>
            <begin position="4"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY36262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="109" mass="11626" checksum="864F25A8D5BE7263" modified="2017-04-12" version="1">MSLVAVCKVSELEADKPLPVDVDDDLTVAIVLHGERIYAIEDQCSHGNVPLSEGDVVDDTIECYLHGSTFDLATGRALNLPATAPVRVFACSTDGDDVFIDVSAPTTDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDI4</accession>
    <name>A0A1Q2CDI4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Solute carrier family 10 (Sodium/bile acid cotransporter), member 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04455</name>
        <name evidence="3" type="ORF">SAMN05428934_101497</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY36827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04455"/>
    <dbReference type="EnsemblBacteria" id="AQP44157">
        <property type="protein sequence ID" value="AQP44157"/>
        <property type="gene ID" value="RPIT_04455"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY36827">
        <property type="protein sequence ID" value="SDY36827"/>
        <property type="gene ID" value="SAMN05428934_101497"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04455"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016833">
        <property type="entry name" value="Put_Na-Bile_cotransptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18640">
        <property type="entry name" value="PTHR18640"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13593">
        <property type="entry name" value="SBF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026166">
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    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <begin position="38"/>
            <end position="53"/>
        </location>
    </feature>
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            <begin position="65"/>
            <end position="87"/>
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            <end position="148"/>
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            <end position="174"/>
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        <location>
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            <end position="248"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY36827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="318" mass="33583" checksum="22604A4957FA037F" modified="2017-04-12" version="1">MKLKLDPTVFLILGALALGLTLPIRGDAAAAFDVVTKVGVFVLFFGYGARLSAAETRAGLINWKLHLTILATTFVVFPLLALPMLAVPGLSEPIRIGLVFLCLVPSTVQMSITMTSLAGGNVPAAMVSATASNIAGVGITPLLAILFFPGADGGGIGFDQLVGVVVQLALPFLLGQLSRFATAGFMARHRSRLKYLDQVVIGLIVYGAFSDLRVSGVWRQLQPLDLVLVVPIVLGLMAAMFWLTWRAGGWLGFPREDRIALMFCGTKKSLATGVPMASVLFGGATVGLLVIPLMLYHQAQLLTGSVVATRMSRSASSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDL2</accession>
    <name>A0A1Q2CDL2_9ACTN</name>
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        <submittedName>
            <fullName evidence="7">Uncharacterized conserved protein, contains PQ loop repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_04685</name>
        <name evidence="7" type="ORF">SAMN05428934_101544</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44199">
        <property type="protein sequence ID" value="AQP44199"/>
        <property type="gene ID" value="RPIT_04685"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37950">
        <property type="protein sequence ID" value="SDY37950"/>
        <property type="gene ID" value="SAMN05428934_101544"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04685"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="57"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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    </feature>
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        <location>
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            <end position="118"/>
        </location>
    </feature>
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        <location>
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            <end position="159"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY37950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="199" mass="21439" checksum="828722AEC8EC732E" modified="2017-04-12" version="1">MFIEVFGWVAAALGVSSNLPQLIRILRERTSAGVSVQLWQVTAASTAAWCVHGFLVSAPQMQWPNLLMAALSSLIVVMVLRDRGEPVLRQFLLPTAVAALLIGSNLWLGALVFGLLVAVPQLVGQFSQLRLMIGAPDLTGVSLGYLSVILLVQTMWFIFGLATVDWALIVCAGSMVVICSINLAVYLVRRAQHRVALAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDQ6</accession>
    <name>A0A1Q2CDQ6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">GTPase Era</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">era</name>
        <name evidence="12" type="ORF">RPIT_05015</name>
        <name evidence="13" type="ORF">SAMN05428934_101609</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8 9">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.</text>
    </comment>
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        <property type="protein sequence ID" value="AQP44253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY39627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05015"/>
    <dbReference type="EnsemblBacteria" id="AQP44253">
        <property type="protein sequence ID" value="AQP44253"/>
        <property type="gene ID" value="RPIT_05015"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY39627">
        <property type="protein sequence ID" value="SDY39627"/>
        <property type="gene ID" value="SAMN05428934_101609"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05015"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04163">
        <property type="entry name" value="Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00367">
        <property type="entry name" value="GTPase_Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030388">
        <property type="entry name" value="G_ERA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005662">
        <property type="entry name" value="GTP-bd_Era"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698">
        <property type="entry name" value="PTHR42698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00436">
        <property type="entry name" value="era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51713">
        <property type="entry name" value="G_ERA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Era-type G" evidence="11">
        <location>
            <begin position="6"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="KH type-2" evidence="10">
        <location>
            <begin position="211"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="G1" evidence="8">
        <location>
            <begin position="14"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="G2" evidence="8">
        <location>
            <begin position="40"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="G3" evidence="8">
        <location>
            <begin position="61"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="G4" evidence="8">
        <location>
            <begin position="125"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="G5" evidence="8">
        <location>
            <begin position="159"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="14"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="61"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="125"/>
            <end position="128"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP44253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY39627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="307" mass="33795" checksum="27F9C4D13DF40344" modified="2017-04-12" version="1">MTDGYKSGFACFVGRPNAGKSTLTNVLVGQKIAISSSKPQTTRHAVRGIVTREDGQLVLIDTPGLHRPRTLLGQRLNDLVFETWSEVDVVGVCLPCDQRIGPGDKFIISEIAKLSNKPTLVALATKTDLVSKERQLSHLVDVGAVAEELGIEWAEVIPCSATAGTQIDEVRDALLNLLPEGPMYYPDGEITDEPEETLIAELIREAALEGVRDELPHSIAVVIDEILPRPDRPEDKPLTDIFASIVVERESQKGIIIGHRGARLKEIGATAREQINRLLGTRVHLSLHVKVLKEWQRDAKYLNRLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDR3</accession>
    <name>A0A1Q2CDR3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA-binding transcriptional regulator YhcF, GntR family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">GntR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04890</name>
        <name evidence="3" type="ORF">SAMN05428934_101586</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY39023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04890"/>
    <dbReference type="EnsemblBacteria" id="AQP44231">
        <property type="protein sequence ID" value="AQP44231"/>
        <property type="gene ID" value="RPIT_04890"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY39023">
        <property type="protein sequence ID" value="SDY39023"/>
        <property type="gene ID" value="SAMN05428934_101586"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04890"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="7"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY39023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="125" mass="13829" checksum="9521D1ADD9E7DEF6" modified="2017-04-12" version="1">MQFDTSSPIWLQLIDEFTRRIVTEQWPAGSRIPGVRDLAGELRVNPNTVQRALAELERQGLARSERTSGRYVTDDTAAIDDARRDLATAAADDFTIRARGLGMSLTAARDLLSRRWSAPPEGSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDU3</accession>
    <name>A0A1Q2CDU3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Magnesium chelatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05175</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05175"/>
    <dbReference type="EnsemblBacteria" id="AQP44278">
        <property type="protein sequence ID" value="AQP44278"/>
        <property type="gene ID" value="RPIT_05175"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05175"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="91"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="323" mass="34362" checksum="AAC0ABEDED9208CA" modified="2017-04-12" version="1">MATMTPLALEFMAPNRLWALLIIVLIAALYVVLSGRTTPRPMSSRLRLVVPKDAAWKRHGAVLLALLSLGALIVAWAIPMDYVNKPRDRATIVVAVDVSWSMEAEDIDPNRLVAAQTSAKAFVDSLPERFNVALVTFAGTPDIAVPPTVDRGAVARAIDAFQLAPSTAVGEGVYRSLEALRQVPPDPDDPEAVPPAAIVLLSDGATNIGRSSAGAAEAAKAAGVPVYTIAYGTDGPNAYVEQDGQRQRVSVDHWELSELARLSGGQKYSAESSGQLRETYEAIRRSVGTERVPAEVTDRYAGLAIVFAVLSALGVISLGARWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDV0</accession>
    <name>A0A1Q2CDV0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SsrA-binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Small protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">smpB</name>
        <name evidence="3" type="ORF">RPIT_05310</name>
        <name evidence="4" type="ORF">SAMN05428934_1039</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">The tmRNA-SmpB complex associates with stalled 70S ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SmpB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY65249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05310"/>
    <dbReference type="EnsemblBacteria" id="AQP44302">
        <property type="protein sequence ID" value="AQP44302"/>
        <property type="gene ID" value="RPIT_05310"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY65249">
        <property type="protein sequence ID" value="SDY65249"/>
        <property type="gene ID" value="SAMN05428934_1039"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05310"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070929">
        <property type="term" value="P:trans-translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09294">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00023">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023620">
        <property type="entry name" value="SmpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000037">
        <property type="entry name" value="SsrA-bd_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30308">
        <property type="entry name" value="PTHR30308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01668">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74982">
        <property type="entry name" value="SSF74982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00086">
        <property type="entry name" value="smpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY65249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="159" mass="18279" checksum="E598C16DC754A243" modified="2017-04-12" version="1">MPRETGRKLVAQNKKARHDYQLGDTYEAGLVLTGTEVKTLRLGRATLTEAYVSVDDHGEVWLINAHIPEYEFGTWRNHSARRTRKLLLNKREIAKLSRALSDSGRTAVPLSLYFKDGYAKVEIAVATGKKDWDKRHDLAERDAKREAERALASRNRYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDV8</accession>
    <name>A0A1Q2CDV8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_05270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44296">
        <property type="protein sequence ID" value="AQP44296"/>
        <property type="gene ID" value="RPIT_05270"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05270"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="170" mass="18031" checksum="C55EAFCEAD83034E" modified="2017-04-12" version="1">MSPAAGVPLDLDGAVLTVPPGWRLYADEVVQDERRLVRLRELTTDTRIQAVVLTSVEEDLNDACLALVADQRQGYTGVAESLAVDVQTDPTGEAVSCNFTGTRTSDSVPNKVEFTLIRRDSDGSTLFFRDTIPSAVPDDSPALAQLTAIECAAADTFGVQVIACATSPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE89</accession>
    <name>A0A1Q2CE89_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA ligase (ATP)</fullName>
            <ecNumber evidence="1">6.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_05820</name>
        <name evidence="9" type="ORF">SAMN05428934_103111</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05820"/>
    <dbReference type="EnsemblBacteria" id="AQP44390">
        <property type="protein sequence ID" value="AQP44390"/>
        <property type="gene ID" value="RPIT_05820"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67988">
        <property type="protein sequence ID" value="SDY67988"/>
        <property type="gene ID" value="SAMN05428934_103111"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05820"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000977">
        <property type="entry name" value="DNA_ligase_ATP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117018">
        <property type="entry name" value="SSF117018"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00574">
        <property type="entry name" value="dnl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_LIGASE_A3" evidence="7">
        <location>
            <begin position="289"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY67988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="506" mass="53634" checksum="C5D0DB9F1DFD3BB8" modified="2017-04-12" version="1">MQLKTLVDAVAEVASTRSRTAKIELLASFLRQVEPEDLRTAIGLLVGKPPQGRLGVGARGLQAHRQRAADRPTLGLGDVGEAFDTLAEASGPGSTAVRASTLAGLMASATRSEQDHLARVILGDVRSGALEGILTDAVAAAAGQPKELVRRAAMLTGDLAETARRAMAGDDLQRIGLTPGVPVLPMLASTAATAAEAIAATGRSSVEHKLDGARLQVHRTGDEVWAYTRSLADITARVPEVVATVAAFPGGDLILDGETLTLDEDGSARPFQESMSRLSSHGGEGSLAVWFFDVLHAEGRTLIDEPLETRRAVLARIVGDRLIRGAETSVPGEAQRVLDDALAAGQEGIVVKSLDAPYAAGRRGNNWVKVKPVYTYDLVVLGIEWGSGRRAGTLSNIHLGARDPEGRFGEPGGFVMVGKTFKGMTDEILRWQTEHFAALETGRTEWGITVAPTTVVEIAIDGVQRSSRYPGGVALRFARVKRYRTGADEKAPAEADTIDTLRALLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEG3</accession>
    <name>A0A1Q2CEG3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06445</name>
        <name evidence="3" type="ORF">SAMN05428934_103234</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44493">
        <property type="protein sequence ID" value="AQP44493"/>
        <property type="gene ID" value="RPIT_06445"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71167">
        <property type="protein sequence ID" value="SDY71167"/>
        <property type="gene ID" value="SAMN05428934_103234"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06445"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY71167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="68" mass="6949" checksum="891B53B71EFC7F0A" modified="2017-04-12" version="1">MTSAPKYYHHGRSPAAWAGSIAAAVGFIIVAIAAMLGPNWTLVIIGAAIVLVAGLATLIMKIMGFGQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEG5</accession>
    <name>A0A1Q2CEG5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">S-adenosylmethionine synthase</fullName>
            <shortName evidence="11">AdoMet synthase</shortName>
            <ecNumber evidence="11">2.5.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">MAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Methionine adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">metK</name>
        <name evidence="17" type="ORF">RPIT_06150</name>
        <name evidence="18" type="ORF">SAMN05428934_103175</name>
    </gene>
    <organism evidence="17 19">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 19" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">RP1T</strain>
        </source>
    </reference>
    <reference evidence="18 20" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">RP1</strain>
        </source>
    </reference>
    <reference evidence="17" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L-methionine</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="11">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 2 divalent ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11 13">Belongs to the AdoMet synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY69575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06150"/>
    <dbReference type="EnsemblBacteria" id="AQP44445">
        <property type="protein sequence ID" value="AQP44445"/>
        <property type="gene ID" value="RPIT_06150"/>
    </dbReference>
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            <end position="241"/>
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        <location>
            <begin position="243"/>
            <end position="382"/>
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        </location>
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        <location>
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            <position position="16"/>
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    <sequence length="395" mass="42187" checksum="6C4B4AD0DDC3E74D" modified="2017-04-12" version="1">MSRLFTSESVTEGHPDKIADSISDAVLDSLLAQDPNARVAVETLITTGMVVVAGEVSTVGYVDVASLARQRILDIGYDSSRKGFDGASCGVAIAIGAQSPDIAQGVDDAYEHRVESDGDAASHQGAGDQGLMFGYACNETPHLMPLPIDLAHRLAERLSAVRKDATLDYLRPDGKTQVTVRYDDEGRPEGIDTVVVSTQHRDDVDLEQIVPDLKREVIAPVLERYGLSAPNRVLVNPTGKFVIGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVAKNVVAAGLADRCEVQVAYAIGKAHPVGFYLDTFGTGAVPEDQIRDAVLATFDLRPGAIIRDLDLLRPIYSEVTVYGHFGRDLPNATWERTDRAEALAAAVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
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                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="entry name" value="Kinase-like_dom_sf"/>
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            <end position="286"/>
        </location>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="AQP44513.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY71766.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="383" mass="41913" checksum="F742E2B85E86D63B" modified="2017-04-12" version="1">MTELKDRLWDLAHSSRWFSGRAGRPAGVELGPELQANSGERYQAAFLDVSFDDGHVERFSVPLRIDGAEPVDACDSAEGLLELLRAGAPGFERLRDVPAGLPARRYRGEQSNTSVFFGDQLIMKVFRRIEPGINVDVELHRALAGTGLAAELYGVWSHDGADLAIFLEALSDPTDGYVLASEHARRGESFGAHARALGEALAAVHAALADRLPTGTLDGDAMATEFERRLDAVCAEVGEVRDHREAVTRSLRSVAGRRLPAQRIHGDCHLGQVLLSGGTWRYVDFEGEPLKTLEQRREPDSPLRDVAGMLRSFDYAAAEGDASPEWLSECRSQFLSGYGIDQAGADAVLGAYETDKAAYEAVYEARYRPHLLRVPLTRLASLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEI3</accession>
    <name>A0A1Q2CEI3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AI-2E family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_06615</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="AQP44524"/>
        <property type="gene ID" value="RPIT_06615"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06615"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
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        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="338"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="382" mass="40734" checksum="9EF3C31FF06B8E19" modified="2017-04-12" version="1">MRSALRRLFGTAGRGARVILTPRPIEVIEPVPPILHDLSARSAPSPFKFGFLGAVGVLVALALAQAVLTVQSVLILVVMAMFLALGLSPAVEFFTRRRMPRPFAVTVVTIAMLAVIALGVTALVPVLTQQTTTLMRNLPGLLNNLAQQPQLAELDEQYDIVAQAQDFITSGTLLNSLFGGLWGAGRLVANLVFSVIVTVVLTIYFLASLPTIKETIYAFAPASRRPRARYLADEIFRGVSGYITGMFVIVSVASVAAFIFMNIAGLGEYSLALAFVVAMFCFIPVVGSFLAMAAVALVGFAVSPAIGIATIIYFLIYQQFDAYVLYPNVMRRTVKVPAALVVLSAIIGGMLFGVIGAVIAIPTLAAVLLLFREIVQPALDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEK6</accession>
    <name>A0A1Q2CEK6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Corrinoid adenosyltransferase</fullName>
            <ecNumber evidence="4">2.5.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Cob(II)alamin adenosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Cob(II)yrinic acid a,c-diamide adenosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Cobinamide/cobalamin adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_06650</name>
        <name evidence="7" type="ORF">SAMN05428934_110117</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 ATP + 2 cob(II)alamin + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)alamin + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:28671"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 ATP + 2 cob(II)yrinate a,c diamide + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)yrinate a,c-diamide + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:11528"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:58503"/>
            <dbReference type="ChEBI" id="CHEBI:58537"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 2/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Cob(I)alamin adenosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.17" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ10354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06650"/>
    <dbReference type="EnsemblBacteria" id="AQP44531">
        <property type="protein sequence ID" value="AQP44531"/>
        <property type="gene ID" value="RPIT_06650"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ10354">
        <property type="protein sequence ID" value="SDZ10354"/>
        <property type="gene ID" value="SAMN05428934_110117"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06650"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00233"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016030">
        <property type="entry name" value="CblAdoTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036451">
        <property type="entry name" value="CblAdoTrfase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029499">
        <property type="entry name" value="PduO-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12213">
        <property type="entry name" value="PTHR12213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01923">
        <property type="entry name" value="Cob_adeno_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89028">
        <property type="entry name" value="SSF89028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00636">
        <property type="entry name" value="PduO_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cob_adeno_trans" evidence="5">
        <location>
            <begin position="7"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ10354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="197" mass="21625" checksum="DBCBC4569A6C1995" modified="2017-04-12" version="1">MVTLSKIYTRTGDAGQTRLSDNSEVPKTDLRVEAYGHVDETNSTIGLAVAHGGLPDRVVEMLALIRNELFDVGADLSTPYDPSPQWAPLRIEQPSIDRLEAYCDELQEDLTVLRSFILPGGNVGGAQLHVARTIARRAERAAWRCAEVFGLDGEGSVNPLAITYLNRLSDLLFIMARAANGTEHEVLWVPGTDREKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEL7</accession>
    <name>A0A1Q2CEL7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription termination factor Rho</fullName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">ATP-dependent helicase Rho</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rho</name>
        <name evidence="12" type="ORF">RPIT_06735</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homohexamer. The homohexamer assembles into an open ring structure.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06735"/>
    <dbReference type="EnsemblBacteria" id="AQP44548">
        <property type="protein sequence ID" value="AQP44548"/>
        <property type="gene ID" value="RPIT_06735"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06735"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008186">
        <property type="term" value="F:ATP-dependent activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01884">
        <property type="entry name" value="Rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011112">
        <property type="entry name" value="Rho_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011113">
        <property type="entry name" value="Rho_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004665">
        <property type="entry name" value="Term_rho"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46425">
        <property type="entry name" value="PTHR46425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07498">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07497">
        <property type="entry name" value="Rho_RNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00959">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00767">
        <property type="entry name" value="rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51856">
        <property type="entry name" value="RHO_RNA_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 8" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="Rho RNA-BD" evidence="11">
        <location>
            <begin position="189"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="28"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="111"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="307"/>
            <end position="312"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="319"/>
            <end position="324"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP44548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="563" mass="61303" checksum="9963A20FB52AAF87" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEM6</accession>
    <name>A0A1Q2CEM6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Diaminopimelate decarboxylase</fullName>
            <shortName evidence="3">DAP decarboxylase</shortName>
            <shortName evidence="3">DAPDC</shortName>
            <ecNumber evidence="3 4">4.1.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lysA</name>
        <name evidence="7" type="ORF">RPIT_06750</name>
        <name evidence="8" type="ORF">SAMN05428934_11097</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>H(+) + meso-2,6-diaminoheptanedioate = CO2 + L-lysine</text>
            <dbReference type="Rhea" id="RHEA:15101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="4.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; L-lysine from DL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.20" evidence="3 4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06750"/>
    <dbReference type="EnsemblBacteria" id="AQP44551">
        <property type="protein sequence ID" value="AQP44551"/>
        <property type="gene ID" value="RPIT_06750"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09964">
        <property type="protein sequence ID" value="SDZ09964"/>
        <property type="gene ID" value="SAMN05428934_11097"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06750"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00027"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008836">
        <property type="term" value="F:diaminopimelate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06828">
        <property type="entry name" value="PLPDE_III_DapDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02120">
        <property type="entry name" value="LysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002986">
        <property type="entry name" value="DAP_deCOOHase_LysA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022657">
        <property type="entry name" value="De-COase2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022653">
        <property type="entry name" value="De-COase2_pyr-phos_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01181">
        <property type="entry name" value="DAPDCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01048">
        <property type="entry name" value="lysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00878">
        <property type="entry name" value="ODR_DC_2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00879">
        <property type="entry name" value="ODR_DC_2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3 4" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="6">
        <location>
            <begin position="72"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Orn_DAP_Arg_deC" evidence="5">
        <location>
            <begin position="326"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="3">
        <location>
            <begin position="319"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="367"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="395"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="424"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ09964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="467" mass="50194" checksum="3C1663847BDC025A" modified="2017-04-12" version="1">MTHMHIAGSIHADATQGGPQWLEVPADLNALDTKLWPRGTVRDDDGRIVVAGIALTDVAQEHGTPTYVIDEADFRSRAAEFRDSFAGWSIFYAGKALLTKTVARWAFEEGLNLDVTTMGEMRIALAGGMPAERLGFHGNNKSDEEIEFALEQGVGRIIVDSFDEIARLERACEAGGHTARVLVRVTTGVEAHTHEYIATAHEDQKFGLSIMGGQALTALVRCHSSRFLDLAGIHSHIGSQIFETHGFEVAIRRTMRLASQFRTATGVELAELDLGGGFGIAYVGADSPLATAEIAAAFEEMVEHECRGFGLSRPHLSIEPGRAICGPAGVALYRVGTVKIVELEGGRSRVYVSVDGGMSDNIRPALYAAEYSAAIANRNSSARPVLCRVVGKHCEGGDILIRDVFLPSDIAIGDLIAVPGSGAYARSMANNYNQIPKPPVVAAKDGVTSVMLRRETLDDIMRLDVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEN5</accession>
    <name>A0A1Q2CEN5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">EcsC protein family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_06570</name>
        <name evidence="2" type="ORF">SAMN05428934_103259</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06570"/>
    <dbReference type="EnsemblBacteria" id="AQP44515">
        <property type="protein sequence ID" value="AQP44515"/>
        <property type="gene ID" value="RPIT_06570"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71846">
        <property type="protein sequence ID" value="SDY71846"/>
        <property type="gene ID" value="SAMN05428934_103259"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06570"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024787">
        <property type="entry name" value="EcsC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12787">
        <property type="entry name" value="EcsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY71846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="221" mass="23263" checksum="7C7EFC4AFE8D4C77" modified="2017-04-12" version="1">MGILDTSGGQANRAVESMVGAFRDIGLDGKASFASAETVARRALADAGNPDDAIRSVIRKHRRGTTAGGFLTGLGGFATLPLLLPTNIFEFYVQATRMVGAIAKIRGYDLGDQEVRARVLASLVGEESGEILANVGLGPIAGAATRRVAKRLPKSPLSEVTKAIGVRLLRRFGLRSARLFGKAIPGLGGVIGAVSDRRQLGRIAQAAKSSFPERTGGRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEN9</accession>
    <name>A0A1Q2CEN9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase sigma factor SigA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">sigA</name>
        <name evidence="9" type="ORF">RPIT_06955</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Interacts transiently with the RNA polymerase catalytic core.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the sigma-70 factor family. RpoD/SigA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="P:DNA-templated transcription, initiation"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="2 5" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
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        <location>
            <begin position="237"/>
            <end position="250"/>
        </location>
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        <location>
            <begin position="406"/>
            <end position="432"/>
        </location>
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    <feature type="DNA-binding region" description="H-T-H motif" evidence="5">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="5">
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            <begin position="213"/>
            <end position="283"/>
        </location>
    </feature>
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            <begin position="292"/>
            <end position="368"/>
        </location>
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        <location>
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            <end position="434"/>
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    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="5">
        <location>
            <begin position="237"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="8"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
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        <source>
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        <source>
            <dbReference type="EMBL" id="AQP44584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="446" mass="49406" checksum="6937F356ECD495F5" modified="2017-04-12" version="1">MKPVDGLERTTVTQNAEGTGKPTRSRRTATSTTDSKPAAKAPAAKKPAARKPAARKPAAKKAAEPTIAEASTGEVEVQFERDGDDVVLTVGGKKRSLDEVDDSQFVEANEAPLEKELVEEEQGFALSDSDDADEPEQQVVSAGATADPVKDYLKQIGKVALLNAVEEVELAKRIEAGLFADERLSSPDHVVSDEDLEDLEWIAEDGRRAKNHLLEANLRLVVSLAKRYTGRGMLFLDLIQEGNLGLIRAVEKFDYTKGYKFSTYATWWIKQAITRAMADQARTIRIPVHMVEVINKLARVQRQMLQDLGREPTPEELAIELDMTPEKVVEVQKYGREPISLHTPLGEDGDSEFGDLIEDSEAVVPADAVNFTLLQEQLNDVLDTLSEREAGVVSMRFGLTDGQPKTLDEIGKVYGVTRERIRQIESKTMSKLRHPSRSQVLRDYLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CER4</accession>
    <name>A0A1Q2CER4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Vitamin B12-dependent ribonucleotide reductase</fullName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">RPIT_07020</name>
        <name evidence="14" type="ORF">SAMN05428934_11041</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = [thioredoxin]-dithiol + a ribonucleoside 5'-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ribonucleoside diphosphate reductase class-2 family.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="4 10"/>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ08856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07020"/>
    <dbReference type="EnsemblBacteria" id="AQP44596">
        <property type="protein sequence ID" value="AQP44596"/>
        <property type="gene ID" value="RPIT_07020"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08856">
        <property type="protein sequence ID" value="SDZ08856"/>
        <property type="gene ID" value="SAMN05428934_11041"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07020"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="RNR_II_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013678">
        <property type="entry name" value="RNR_2_N"/>
    </dbReference>
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        <property type="entry name" value="RNR_lg_C"/>
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    <dbReference type="InterPro" id="IPR013344">
        <property type="entry name" value="RNR_NrdJ/NrdZ"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
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        <property type="entry name" value="NrdJ_Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="8 10" id="KW-0170">Cobalt</keyword>
    <keyword evidence="7 10" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="53"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="RIBORED_LARGE" evidence="11">
        <location>
            <begin position="157"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014409"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP44596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDZ08856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="943" mass="103023" checksum="E494636FE29AE2DA" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEV7</accession>
    <name>A0A1Q2CEV7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_07385</name>
        <name evidence="4" type="ORF">SAMN05428934_11434</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000014">
        <property type="protein sequence ID" value="SDZ18440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07385"/>
    <dbReference type="EnsemblBacteria" id="AQP44654">
        <property type="protein sequence ID" value="AQP44654"/>
        <property type="gene ID" value="RPIT_07385"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ18440">
        <property type="protein sequence ID" value="SDZ18440"/>
        <property type="gene ID" value="SAMN05428934_11434"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07385"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041682">
        <property type="entry name" value="AAA_14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025420">
        <property type="entry name" value="DUF4143"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13173">
        <property type="entry name" value="AAA_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13635">
        <property type="entry name" value="DUF4143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_14" evidence="1">
        <location>
            <begin position="20"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4143" evidence="2">
        <location>
            <begin position="196"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ18440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="423" mass="45030" checksum="CFDB65077944332E" modified="2017-04-12" version="1">MEYARRILDDELDELFGQVPAIAVDGAKGVGKTTTAEQRVTGVVRLDSKAIRESIAAEPEQVLGRGRSLLIDEWQKVPEVWDVVRRAVDADPTGGQFLLVGSASPAPGATAHSGAGRIGRLRMRPMTLSERGVTQPTVSLRGLLGGGRGPLAGSCPLTLSDYVEEIVASGFPAMRRLVGRSRRFQLDSYLHNAVDRDVPEQGLAVRKPEAMLTWLRAYAAATATTASYAQILDAATPGQGDKPARSTSIAYRDVLSSLWLLDPVPAWAPTGSLLTRLGQTPKHHLADPGLAARLLGLSRDALLDGVGTSVGPQSGSVLGHLFESLVTLCVRVPAQAAEASVGHLRTRNGDHEVDLVVVRDDGRALAVEVKLANTVTDQDTKHLHWLADRMGDKLLDAVVINTGPNAYRRPDGIAVVPLGLLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEX2</accession>
    <name>A0A1Q2CEX2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07475</name>
        <name evidence="3" type="ORF">SAMN05428934_11910</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000019">
        <property type="protein sequence ID" value="SDZ21936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44669">
        <property type="protein sequence ID" value="AQP44669"/>
        <property type="gene ID" value="RPIT_07475"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ21936">
        <property type="protein sequence ID" value="SDZ21936"/>
        <property type="gene ID" value="SAMN05428934_11910"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07475"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544455" evidence="1">
        <location>
            <begin position="29"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ21936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="200" mass="20725" checksum="FF9E81F06DAA0564" modified="2017-04-12" version="1">MRRRHLLTAAPALAAALVLSACTPGPDAAPTAPSTAPAAIDAAALLAPFDLTGRDGRELVDHLETLGGDDRPSELMASVRTDHLLLTTDAGEATLPLPADLFYVSVAPFAETTHECFYHSLTTCQGELVDTPVTLTVTDGDGTVVHTAETRTGANGFVGTWLPRGTTGTLSVTTEDGRTGQVNLGTSDDDPTCVTTLRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEZ9</accession>
    <name>A0A1Q2CEZ9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44677">
        <property type="protein sequence ID" value="AQP44677"/>
        <property type="gene ID" value="RPIT_07535"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07535"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="256" mass="28190" checksum="438F161D9F8B731A" modified="2017-04-12" version="1">MGPAFGVTLAISATAERLGVRPTLATITCLAVFVSYGLFHTWRAARETANPAKIRLVRIISHGLSTLGGFVGFHARNLFAVLIPYPSELLNAVWTAMFAALVYSGATRLLSRETDSRSLFLRARRDMGLDAWNYAKAASRIHEVPSVAVHAIILAEAVQRPRWFRKIETVLPPLMRMAGRDATTGIAQMRSVTALSDEESIDMLCIDMKNWLSHHPDVSLENLDDFGDYATHHSADAVFVDSAKGFHAELAELITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF02</accession>
    <name>A0A1Q2CF02_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase</fullName>
            <ecNumber evidence="2">2.5.1.145</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lgt</name>
        <name evidence="3" type="ORF">RPIT_07290</name>
        <name evidence="4" type="ORF">SAMN05428934_11415</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-cysteinyl-[prolipoprotein] = H(+) + S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[prolipoprotein] + sn-glycerol 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:56712"/>
            <dbReference type="Rhea" id="RHEA-COMP:14679"/>
            <dbReference type="Rhea" id="RHEA-COMP:14680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57685"/>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
            <dbReference type="ChEBI" id="CHEBI:140658"/>
            <dbReference type="EC" id="2.5.1.145"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; lipoprotein biosynthesis (diacylglyceryl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Lgt family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.145" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000014">
        <property type="protein sequence ID" value="SDZ18042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07290"/>
    <dbReference type="EnsemblBacteria" id="AQP44635">
        <property type="protein sequence ID" value="AQP44635"/>
        <property type="gene ID" value="RPIT_07290"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ18042">
        <property type="protein sequence ID" value="SDZ18042"/>
        <property type="gene ID" value="SAMN05428934_11415"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07290"/>
    <dbReference type="UniPathway" id="UPA00664"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008961">
        <property type="term" value="F:phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01147">
        <property type="entry name" value="Lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001640">
        <property type="entry name" value="Lgt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30589">
        <property type="entry name" value="PTHR30589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01790">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="220"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)</name>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ18042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="266" mass="28151" checksum="25DD27814D821022" modified="2017-04-12" version="1">MWPEVFSIFGVGIQSYGLSKALALLVGAFLLGRAFTRIGYDKELAHSIALWATVWGFVGAKVYYLIANWDNFSWHLFGGSGFVWYGGLIAGSIAVIVMTRRHDLPLGRVAGAMAAPLSVAYGIGRIGCFLAGDGTYGTPTDLPWGMAFPNGVVPVDVPVHPVQLYEAAGAFLIAGILWVLGRRLRPVAVFGSYLMLSGAARLLAEMVRINPHVVLDLTEAQLIGIASIILGAALILRDTFHPAAPVSNVSAADPSSAAPSPHPVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF31</accession>
    <name>A0A1Q2CF31_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44665">
        <property type="protein sequence ID" value="AQP44665"/>
        <property type="gene ID" value="RPIT_07455"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07455"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029470">
        <property type="entry name" value="PDDEXK_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14281">
        <property type="entry name" value="PDDEXK_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="252" mass="28677" checksum="7329035E88A2D212" modified="2017-04-12" version="1">MPGRSSELGFNVFDVMHHGLHEKQISNVFRWLLDAGGTHRMGDKFTRIFMDEVNRARPSEVPFALGGYWVRQEVNTSDPTDPGDIADLVLESETSVVVIENFVTSDGHGHDYDRYLAYGQRKGGRGVVVLLCRDEDPSLQTKGWQHARVVTYATLITRLREELASDGRWRRENPEAYMFIEQLHRKFVRGEGPCRMGKCWISSWRCARRGRRADTRYRARLSQPSSSPTTSPSRLGNALARGENCCSESGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF92</accession>
    <name>A0A1Q2CF92_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44773">
        <property type="protein sequence ID" value="AQP44773"/>
        <property type="gene ID" value="RPIT_08120"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08120"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="305" mass="29102" checksum="295A59E3D3C0F637" modified="2017-04-12" version="1">MNPFLTVVVAPSVEGPLAITPWSAIIPIAPGATLASTIVAPVVGATLTVLTRAAVIAITEGSALTATVVAIPIGPPLTVLTGTTVIATGPTVVAIAVGTSLAVLTGTTVVPTWAAVVAVTEGSALTATVVAIPIGTALTVLAGTTVIATGPTVVAITIGSALNATVVAIPIGTALAVLARATVVPTGPTVVAVTEGSALSPAVVAATPRPTLTVLPRAAVVAITEGSALAATVVAVAIGSALTAAIVTVTIGTALAVLTRAAVVAIPKRPALAPAVVAVTPRTTLAVLTRAPVVPARAAVVSSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFK6</accession>
    <name>A0A1Q2CFK6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aspartate carbamoyltransferase</fullName>
            <ecNumber evidence="5">2.1.3.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Aspartate transcarbamylase</fullName>
            <shortName evidence="5">ATCase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pyrB</name>
        <name evidence="9" type="ORF">RPIT_08945</name>
        <name evidence="10" type="ORF">SAMN05428934_107102</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>carbamoyl phosphate + L-aspartate = H(+) + N-carbamoyl-L-aspartate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20013"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.2" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08945"/>
    <dbReference type="EnsemblBacteria" id="AQP44901">
        <property type="protein sequence ID" value="AQP44901"/>
        <property type="gene ID" value="RPIT_08945"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98288">
        <property type="protein sequence ID" value="SDY98288"/>
        <property type="gene ID" value="SAMN05428934_107102"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08945"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00116"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004070">
        <property type="term" value="F:aspartate carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00001">
        <property type="entry name" value="Asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002082">
        <property type="entry name" value="Asp_carbamoyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF16">
        <property type="entry name" value="PTHR11405:SF16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00670">
        <property type="entry name" value="asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="8">
        <location>
            <begin position="2"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="7">
        <location>
            <begin position="156"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY98288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="309" mass="33213" checksum="AD85C3685BC7CA2C" modified="2017-04-12" version="1">MKHLLSIADLSRDEVDSLLATAEEMHDVQSRPIKKLPALRGRTVVNLFFEDSTRTRSSFELAAKWLSADAINVSAKGSSVSKGESMRDTLLTLDAMGVDAIIMRHAGSGSVAQAAGWVKASMINAGDGMHEHPTQALLDAHAISRHLRALGRGSLEGKRVAITGDLLHSRVVRSNVLLLDKLGAYVVLVAPPTLLPPGVETWGVEVSQDFDAVLPDVDVAMMLRVQRERMSGGFFPSEREYIDGYGLTPRRLALLPDHACIAHPGPMNRGLEISSAAADAARSIILDQVSAGVAVRMSVLYHLLAGEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFM9</accession>
    <name>A0A1Q2CFM9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoside diphosphate kinase</fullName>
            <shortName evidence="1">NDK</shortName>
            <shortName evidence="1">NDP kinase</shortName>
            <ecNumber evidence="1">2.7.4.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Nucleoside-2-P kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ndk</name>
        <name evidence="4" type="ORF">RPIT_08765</name>
        <name evidence="5" type="ORF">SAMN05428934_10763</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:44640"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:18113"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the NDK family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08765"/>
    <dbReference type="EnsemblBacteria" id="AQP44870">
        <property type="protein sequence ID" value="AQP44870"/>
        <property type="gene ID" value="RPIT_08765"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97579">
        <property type="protein sequence ID" value="SDY97579"/>
        <property type="gene ID" value="SAMN05428934_10763"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08765"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006165">
        <property type="term" value="P:nucleoside diphosphate phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00451">
        <property type="entry name" value="NDP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="SSF54919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NDK" evidence="3">
        <location>
            <begin position="2"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="1">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY97579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="135" mass="14792" checksum="255293BFE39F6B9D" modified="2017-04-12" version="1">MTEHTFVIIKPDAVEAGHVGAILGRYEAAGLRVEAMDLRRIDAGFADRHYAEHLERDFYPPLREFMTSGPLVAVILSGADAISTVRGINGATDPTQAEPGTIRADFAENTRRNAVHASDSRESAEREISLWFPKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFV0</accession>
    <name>A0A1Q2CFV0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">3-dehydroquinate dehydratase</fullName>
            <shortName evidence="7">3-dehydroquinase</shortName>
            <ecNumber evidence="5 7">4.2.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Type II DHQase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">aroQ</name>
        <name evidence="11" type="ORF">RPIT_09560</name>
        <name evidence="12" type="ORF">SAMN05428934_102394</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes a trans-dehydration via an enolate intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>3-dehydroquinate = 3-dehydroshikimate + H2O</text>
            <dbReference type="Rhea" id="RHEA:21096"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="EC" id="4.2.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 7">Homododecamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the type-II 3-dehydroquinase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.10" evidence="5 7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY59604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09560"/>
    <dbReference type="EnsemblBacteria" id="AQP45002">
        <property type="protein sequence ID" value="AQP45002"/>
        <property type="gene ID" value="RPIT_09560"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59604">
        <property type="protein sequence ID" value="SDY59604"/>
        <property type="gene ID" value="SAMN05428934_102394"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09560"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00086"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003855">
        <property type="term" value="F:3-dehydroquinate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00466">
        <property type="entry name" value="DHQase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.9100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00169">
        <property type="entry name" value="AroQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001874">
        <property type="entry name" value="DHquinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018509">
        <property type="entry name" value="DHquinase_II_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036441">
        <property type="entry name" value="DHquinase_II_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21272">
        <property type="entry name" value="PTHR21272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01220">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001399">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52304">
        <property type="entry name" value="SSF52304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01029">
        <property type="entry name" value="DEHYDROQUINASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7 9">
        <location>
            <begin position="100"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 8">
        <location>
            <position position="23"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7 8">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7 10">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP45002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY59604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="142" mass="15145" checksum="41407CA62E912C87" modified="2017-04-12" version="1">MRKVFVLNGPNLGRLGTRQTDVYGAVTYSDLAAHLVETGEGMGLDVEVRQTEHEGEMITWLHEAADAQAAVVLNAGAWTHYSYAIADAAALVPFYVEVHISNVHAREEFRRHSVLSANASGIIVGCGVGGYDLALAHVVASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG49</accession>
    <name>A0A1Q2CG49_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Peptide/nickel transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_10025</name>
        <name evidence="7" type="ORF">SAMN05428934_102301</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10025"/>
    <dbReference type="EnsemblBacteria" id="AQP45084">
        <property type="protein sequence ID" value="AQP45084"/>
        <property type="gene ID" value="RPIT_10025"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56957">
        <property type="protein sequence ID" value="SDY56957"/>
        <property type="gene ID" value="SAMN05428934_102301"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10025"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="201"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="432"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="476"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="100"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY56957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="506" mass="55351" checksum="8DFF668FECFB498E" modified="2017-04-12" version="1">MIRYIARRLGISLLILLLGSLLLFVLTINSGDPLEDLRESNAPNRENLINQRISFMGLDRPWYERYFDWLGGASKCLIGACDLGVDRKGQDVGAMVVTAAGSTLRLVVLATVFAIMLGVTLGIVTAIRQYSGFDYAVTFMAFVFFSLPVFWFAVLLKHYAAIEFNNWIVDAAISPPMVLLFAAVLAFILMAALGGDWKRRLITFGAAFVVFAGALFYFDAVTWFRVPSIGLPIFAIAALALAALIVQMTSGLDNKNVRNAVATTTVVGIIAYAVLRGTLMTNPSTLLLFVCLAAAIAVALISGYFWGGFSRRQAMTSSFIWALLASLLALADLALSNWSSYLREQPRPIPTIGSETPNYNSTYWNHFLDSATHLILPTIVLTLISVAAYTRYTRASMLDVLNQDYIRTARSKGISERKVITRHAFRNSMIPLATIVAFDFAGLIGGAVITETVFGWQGMGNMFKVGLAQVDPMPVMAFFLVTGTAAVVMNMIADLAYAVLDPRITR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG51</accession>
    <name>A0A1Q2CG51_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Peptidase family M23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09985</name>
        <name evidence="3" type="ORF">SAMN05428934_102309</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY57156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09985"/>
    <dbReference type="EnsemblBacteria" id="AQP45077">
        <property type="protein sequence ID" value="AQP45077"/>
        <property type="gene ID" value="RPIT_09985"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57156">
        <property type="protein sequence ID" value="SDY57156"/>
        <property type="gene ID" value="SAMN05428934_102309"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09985"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M23" evidence="1">
        <location>
            <begin position="99"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY57156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="207" mass="21797" checksum="4786ECBF5402660B" modified="2017-04-12" version="1">MDLRYPFTGRWLVQNSPADRVPSHGTTAFATSYAIDFVPVDDRGRTAPFGLRSLLRPQAPDAFPGFRRAILAPVDGVVVAAHGAELDHAAYRGLSSVGYAVTQGRRVAEGWLALAGNHVLIRCATGDVVALCHLQQGSVSVRVDQPVRAGDPVGRCGNSGNSTEPHVHVQAIDRLDVGAALPVPITFDGGLPRGGEIVVAHLGNRTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG69</accession>
    <name>A0A1Q2CG69_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3117 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10175</name>
        <name evidence="2" type="ORF">SAMN05428934_102270</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10175"/>
    <dbReference type="EnsemblBacteria" id="AQP45111">
        <property type="protein sequence ID" value="AQP45111"/>
        <property type="gene ID" value="RPIT_10175"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56123">
        <property type="protein sequence ID" value="SDY56123"/>
        <property type="gene ID" value="SAMN05428934_102270"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10175"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021465">
        <property type="entry name" value="DUF3117"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11314">
        <property type="entry name" value="DUF3117"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY56123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="55" mass="5697" checksum="1DDBB006BB466229" modified="2017-04-12" version="1">MAAMKPRTGDGPMEVTKEGRGIVMRVPVDGGGRLVVEMNATEATDLLNALKGVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGA4</accession>
    <name>A0A1Q2CGA4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_10055</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10055"/>
    <dbReference type="EnsemblBacteria" id="AQP45090">
        <property type="protein sequence ID" value="AQP45090"/>
        <property type="gene ID" value="RPIT_10055"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10055"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
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        <location>
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            <end position="455"/>
        </location>
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        <location>
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        </location>
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        </location>
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        <location>
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        </location>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
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    </evidence>
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            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
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        <source>
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        </source>
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            <dbReference type="PROSITE" id="PS51195"/>
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    </evidence>
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        <source>
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    <sequence length="679" mass="76111" checksum="0F021D54B12C5668" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
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        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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        </source>
    </reference>
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</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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            <dbReference type="EMBL" id="AQP45322.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="63" mass="6686" checksum="3693C84D8509BDBD" modified="2017-04-12" version="1">MIQDRPPTAAAHRLSAPGGGEREASVRRVGLDVAKYLAELGSGRRLITPRDAPAMRGVALIVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGU9</accession>
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">RP1</strain>
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    </reference>
    <reference evidence="2" key="3">
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="SAMN05428934_10277"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="209"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP45280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY50330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="239" mass="26163" checksum="2F358F7588E42C9F" modified="2017-04-12" version="1">MQTLVVCAVSIDDVRDIFRADEALAARLRALAADTFSPPTAQKRRWFGPVLRHDEVRVDPAAPTHADMDAVLTGSFVAPDRLPQAWTLVATWVQGVAAASAKVPWNLARTEQIEFDLARAGLNSDYALRNLAERDLGIPLRRLPDQIAGYAKHVQVVETLDALRSIDQRPEFTPEAHAVVDQLVGVLETAANDPHLDLVAFTVPTNQSLSSAERQRGASVESVPEQRRAPARSVRRTGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGV4</accession>
    <name>A0A1Q2CGV4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase DDE domain group 1</fullName>
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    <gene>
        <name evidence="2" type="ORF">RPIT_11545</name>
        <name evidence="3" type="ORF">SAMN05428934_106166</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY94348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11545"/>
    <dbReference type="EnsemblBacteria" id="AQP45352">
        <property type="protein sequence ID" value="AQP45352"/>
        <property type="gene ID" value="RPIT_11545"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY94348">
        <property type="protein sequence ID" value="SDY94348"/>
        <property type="gene ID" value="SAMN05428934_106166"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11545"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13701">
        <property type="entry name" value="DDE_Tnp_1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="1">
        <location>
            <begin position="3"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY94348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="114" mass="11774" checksum="D05D7C544001C103" modified="2017-04-12" version="1">MKSTGSYPRVHVDTAKVTAVGQAGGILLTETIRAAGLDLALSEAMSRWRRPLAIHDPGKIICDLAVSLVLGGEALSDLATLRAEPGVYGPVASDPTVSRLIATLAEDAEAPLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGV5</accession>
    <name>A0A1Q2CGV5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11540</name>
        <name evidence="3" type="ORF">SAMN05428934_106167</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY94374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45351">
        <property type="protein sequence ID" value="AQP45351"/>
        <property type="gene ID" value="RPIT_11540"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY94374">
        <property type="protein sequence ID" value="SDY94374"/>
        <property type="gene ID" value="SAMN05428934_106167"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11540"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY94374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="144" mass="15228" checksum="FF9E6902A36C9FC8" modified="2017-04-12" version="1">MMSTATFELKPWAFVVYSLVFGIAGLAAVGYVDPEMRLAGFDGLVFGFYGHASNVLISYAVIVVYGTIRLVMGAKIRELAVATGVIVAANYVYEVGLTLWNTKDLADAHWGAASSLLTLALLAAIHRFGVKPAASASVTVKARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGV7</accession>
    <name>A0A1Q2CGV7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">D-xylose ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Monosaccharide ABC transporter ATP-binding protein, CUT2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_11505</name>
        <name evidence="6" type="ORF">SAMN05428934_1022</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY47988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11505"/>
    <dbReference type="EnsemblBacteria" id="AQP45346">
        <property type="protein sequence ID" value="AQP45346"/>
        <property type="gene ID" value="RPIT_11505"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY47988">
        <property type="protein sequence ID" value="SDY47988"/>
        <property type="gene ID" value="SAMN05428934_1022"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11505"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="253"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY47988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="505" mass="55400" checksum="7B127FB810411058" modified="2017-04-12" version="1">MTKLLELKNVSKTFPGVKALQNVHLDLNAGEVLGLCGENGAGKSTLMKVLTGIYKPDPGAEIWLQGEKVQVRDVNHARDLGLSIIHQELNMVPDLTVAQNLYLGRPGSHKAGWVNDAQMNRDAGELFDKLGMSVDPKARIGDLSVARQQMVEIARALSYNSRILVMDEPTAALTIAETEALFGMIRDFVTPETGLIYISHRMPEIEEITDRVSVLRDGQYVGTVTTDEVEMREIISMMVGREVSGDARPRNKVTSDEIVLSVRDLNTKKLLHDINFDVRRGEILGFAGLMGAGRTEVARCVFGADPRTSGEIHVNGKKVDIRTAADGVRAGIGYLSEDRKTFGLLLDQDIKANTVMAAMKDFNIGGFILDNKIRTVGTEYSDRLRVKTPSVNQLLGKLSGGNQQKVVIAKWLVRNCDVLIFDEPTRGIDVGAKEEIYALLEQLCEQGKGIVMISSELPEVLRMSHRIAVMAHGRITGILENEDATQENIMELATVGKAQLNGEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGX2</accession>
    <name>A0A1Q2CGX2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mannose-6-phosphate isomerase</fullName>
            <ecNumber evidence="3">5.3.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_11215</name>
        <name evidence="8" type="ORF">SAMN05428934_10261</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-mannose 6-phosphate = D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12356"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="5.3.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the mannose-6-phosphate isomerase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.8" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY49863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11215"/>
    <dbReference type="EnsemblBacteria" id="AQP45295">
        <property type="protein sequence ID" value="AQP45295"/>
        <property type="gene ID" value="RPIT_11215"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY49863">
        <property type="protein sequence ID" value="SDY49863"/>
        <property type="gene ID" value="SAMN05428934_10261"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11215"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004476">
        <property type="term" value="F:mannose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001250">
        <property type="entry name" value="Man6P_Isoase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016305">
        <property type="entry name" value="Mannose-6-P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10309">
        <property type="entry name" value="PTHR10309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01238">
        <property type="entry name" value="PMI_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001480">
        <property type="entry name" value="Mannose-6-phosphate_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00714">
        <property type="entry name" value="MAN6PISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00218">
        <property type="entry name" value="manA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="active site" evidence="4">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001480-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001480-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY49863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="393" mass="42342" checksum="4779F9BE1F991DB6" modified="2017-04-12" version="1">MRRLTGHVQHFAWGSHDEIPAILRREPDGQPWAEYWLGTHPGGPAHLEDGTSLEDFLLSHPEMIGEATHAAFGARLPFLLKLLSAGSPLSLQAHPSREQAEVGYARESLLGLDPADPTRVFKDDWPKPEAIVALTPFEGLLGFRDPVETAGLFEGLGVADELQSVIGPLRDRSDILGLQEVFLDVLSLEDDRRHLVDEVLAAAVNHLQAPGALGEFARTAVELDEHFPGDPGILAALLLNRISLEPGQAVALEAGVMHAYLRGTGVEIMANSDNVIRGGLTKKHIDVDGLLHVVDFTPLVPHILNAEGADGIYVYPTPFPEFELWLVSPVSDDTLNLPRSDSARIALVTDGEFHLEGDDGIRRLGCGDAAFLCADEHVALTGQGQLFVAASGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGX3</accession>
    <name>A0A1Q2CGX3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Fructose-bisphosphate aldolase</fullName>
            <shortName evidence="13">FBP aldolase</shortName>
            <ecNumber evidence="5 13">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">RPIT_11555</name>
        <name evidence="15" type="ORF">SAMN05428934_106164</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1T</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1</strain>
        </source>
    </reference>
    <reference evidence="14" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12 13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12 13">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="5 13"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY94308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11555"/>
    <dbReference type="EnsemblBacteria" id="AQP45354">
        <property type="protein sequence ID" value="AQP45354"/>
        <property type="gene ID" value="RPIT_11555"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY94308">
        <property type="protein sequence ID" value="SDY94308"/>
        <property type="gene ID" value="SAMN05428934_106164"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11555"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006411">
        <property type="entry name" value="Fruct_bisP_bact"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30559">
        <property type="entry name" value="PTHR30559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00167">
        <property type="entry name" value="cbbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01520">
        <property type="entry name" value="FruBisAldo_II_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00602">
        <property type="entry name" value="ALDOLASE_CLASS_II_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00806">
        <property type="entry name" value="ALDOLASE_CLASS_II_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12 13" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Dihydroxyacetone phosphate binding" evidence="11">
        <location>
            <begin position="250"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Dihydroxyacetone phosphate binding" evidence="11">
        <location>
            <begin position="271"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>dihydroxyacetone phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU366023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="AQP45354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="SDY94308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="342" mass="36652" checksum="7A1D23EEBC2A9BD9" modified="2017-04-12" version="1">MPVATPEVYAEMLDRAKAGKFAYPAINVSSSQTLHAALQGFAEAGSDGILQVSTGGAEYFSGPTIKDKVTGAAAFAAFAQEVAKNYPITVALHTDHCPKDKLDSFVRPLLALSEERVAKGQLPLFQSHMWDGSAVPMEENLQIADELLARCAAANIILEIEVGVVGGEEDGVAAEINDKLYTTVEDGMRTVEVLGLGEKGRYITALTFGNVHGVYKPGAVKLRPEVLKEIQDAVGQKHGKESPFDLVFHGGSGSTAQEISDAVDYGVIKMNIDTDTQYAFTRPVVEHMFRNYDGVLKIDGEVGNKKMYDPRAWGKAAEAGMAARVVEACQQLRSAGQSLSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH41</accession>
    <name>A0A1Q2CH41_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_11990</name>
        <name evidence="4" type="ORF">SAMN05428934_10677</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11990"/>
    <dbReference type="EnsemblBacteria" id="AQP45431">
        <property type="protein sequence ID" value="AQP45431"/>
        <property type="gene ID" value="RPIT_11990"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92347">
        <property type="protein sequence ID" value="SDY92347"/>
        <property type="gene ID" value="SAMN05428934_10677"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11990"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="20"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY92347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="393" mass="40158" checksum="131E2FA7643DCB32" modified="2017-04-12" version="1">MTENGEAPGSQASLREANSARLLNALTRYGQLTQVELAAATGLSPATVSNIVRQLVADGAVETSVTTRSGRRAQLVTLARNDSMTAGIHAGPRSLDVTLVDANLREVARQHLPLPAAHRFDTTLDRAALLVSELTSERGIGLHDLVGVGVAMPAGGRVGADPGLPSWAGVDVADTLGRRLGRPVFVTREIDAAASAEARLGALRGTECGIYVRVGDTTDSAIVIRGSVLRVGTHAAAGIGHVRVSPGGAICRCGGRGCLNTEVSIDSLRESLRISHGPMSLRDIVSAAKGGDPGCQQVISDAGAAIGSALADLATALGPDRISVGGPLARAGDILLSPIRDALEARPVLRGAEGLLGAGHLNESAETLGAAAYVFDMMSLVPMPDTARGGGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH53</accession>
    <name>A0A1Q2CH53_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12045"/>
    <dbReference type="EnsemblBacteria" id="AQP45442">
        <property type="protein sequence ID" value="AQP45442"/>
        <property type="gene ID" value="RPIT_12045"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12045"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="134" mass="14140" checksum="BF766A1E1AA41CB3" modified="2017-04-12" version="1">MLRGLTLLTLLGVGYWVWWAWGDQLMGADEPEPTPTTTAVASPTYSPPFPGVPEEATDCQNGTATTGKSSCEFAQEILKAYGAVPAADRPQGATVTLPAVPDPVRQSAFDTQCLVGKPTVTCFVGPEKVYIHAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH81</accession>
    <name>A0A1Q2CH81_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_12000</name>
        <name evidence="7" type="ORF">SAMN05428934_10675</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12000"/>
    <dbReference type="EnsemblBacteria" id="AQP45433">
        <property type="protein sequence ID" value="AQP45433"/>
        <property type="gene ID" value="RPIT_12000"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92307">
        <property type="protein sequence ID" value="SDY92307"/>
        <property type="gene ID" value="SAMN05428934_10675"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12000"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="319"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY92307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="349" mass="36929" checksum="28818E45372C192E" modified="2017-04-12" version="1">MREVASVSGVAIKTVSRVMRGEPNVAPATAERVRKTARDLGYVMHKQASDLRRLDGSPGAIGLLLSSVGNAFDSKVHRAIERVANEAGMITLAASTEDDPAVELERLEGFVARRLDGLVLMTVRADHDLLVREIERGFPVVLVDRPANDLDCDTVTSDNAQGILAAVDHVRSRGHERIAFLANVQTISTSRERAAAFRSATQDLVGCSAITGLTTETEVIAAVEGLMSAEAPPTAIISGRNDISIATVRALQRLGLEETVALVGFDEVPLADLIRPGLTVIAQDPDAMGELAARRLLARIRGEELPAEHVTVPTRLIARGSGEIRPPARQADDGLAAQASGASGIGSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH83</accession>
    <name>A0A1Q2CH83_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">L-lactate dehydrogenase</fullName>
            <shortName evidence="6">L-LDH</shortName>
            <ecNumber evidence="4 6">1.1.1.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ldh</name>
        <name evidence="12" type="ORF">RPIT_11905</name>
        <name evidence="13" type="ORF">SAMN05428934_10694</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the conversion of lactate to pyruvate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>(S)-lactate + NAD(+) = H(+) + NADH + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:23444"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16651"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.27"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="6">Allosterically activated by fructose 1,6-bisphosphate (FBP).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Fermentation; pyruvate fermentation to lactate; (S)-lactate from pyruvate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the LDH/MDH superfamily. LDH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.27" evidence="4 6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11905"/>
    <dbReference type="EnsemblBacteria" id="AQP45415">
        <property type="protein sequence ID" value="AQP45415"/>
        <property type="gene ID" value="RPIT_11905"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92755">
        <property type="protein sequence ID" value="SDY92755"/>
        <property type="gene ID" value="SAMN05428934_10694"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11905"/>
    <dbReference type="UniPathway" id="UPA00554">
        <property type="reaction ID" value="UER00611"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004459">
        <property type="term" value="F:L-lactate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00488">
        <property type="entry name" value="Lactate_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011304">
        <property type="entry name" value="L-lactate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="L-LDH-NAD"/>
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    </dbReference>
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    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
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        <location>
            <begin position="7"/>
            <end position="146"/>
        </location>
    </feature>
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            <begin position="149"/>
            <end position="309"/>
        </location>
    </feature>
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            <end position="127"/>
        </location>
    </feature>
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            <begin position="152"/>
            <end position="155"/>
        </location>
    </feature>
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        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
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            <position position="38"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
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            <position position="43"/>
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        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
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        <location>
            <begin position="83"/>
            <end position="84"/>
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        <ligand>
            <name>NAD(+)</name>
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        </ligand>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:32966"/>
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            <position position="172"/>
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        <location>
            <position position="224"/>
        </location>
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        <source>
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        </source>
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            <dbReference type="Pfam" id="PF00056"/>
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            <dbReference type="Pfam" id="PF02866"/>
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        <source>
            <dbReference type="EMBL" id="SDY92755.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="316" mass="33142" checksum="5407B1A00A06BD05" modified="2017-04-12" version="1">MSKRASTKLAVVGAGAVGTSLAYAALIRGVASEVVLHDINEKKVRAEALDLAHGSQFLPSVSIDASADVAVTAGSDVVVVAAGAKQKHGETRMDLAEHTVDLMKKMIPPLVDASPEAVFVMVTNPVDVTTQAALKISGLPAGQLFGSGTVLDSSRLRWLVAKECGVAVGNVHGYICGEHGDSETPLWSTAAIGGVPLNEWEHQTGQLGESKRDEIADRVVRAAYEVIDGKGATNYAIGLAGTRIIQAILRDENAVLSVSSLLDDWHGISDVCMSVPHILGAGGVRQALRLPVSDDELDKLRASADSIRSVVRRLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH94</accession>
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        <submittedName>
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        </submittedName>
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 9">RP1T</strain>
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                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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        <property type="protein sequence ID" value="SDY90744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP45496">
        <property type="protein sequence ID" value="AQP45496"/>
        <property type="gene ID" value="RPIT_12360"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY90744"/>
        <property type="gene ID" value="SAMN05428934_1064"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="MFS_trans_sf"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
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        </location>
    </feature>
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            <end position="320"/>
        </location>
    </feature>
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            <end position="351"/>
        </location>
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        <location>
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            <end position="445"/>
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    </feature>
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        <location>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45496.1"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY90744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="456" mass="48330" checksum="98F16F8D278CC0DE" modified="2017-04-12" version="1">MSGHLTRSQRLDELPYTRKHNKLLMGSGVGWALDAMDIGLISFIMAALASEWQLSSTELSFLGSVGFVGMALGASLGGLLADRIGRRQVFALTLLIYGVATGLSALSTGLVMLIALRFIVGLGLGAELPVASTLVSEFAPRKIRGRVVVALESFWAVGWLAAALIGFFIVPMDNGWRWALALGAVPAAWSMVIRFGLPESVRFLEGKGRHNEAEQVVSKFEEAAGVTVRDEDKAPDAPLQAGAKVTKRELFGPRFRTRTIALWLTWFGINFAYYGAFIWLPTLLSSEGGMNLRDSFEFTLYMTLAQLPGYLAAAILVEVWGRRPTLVTFLGGSMVGAAAFALAPTLAASIAPGDDGAAYAIALTAGCVLSFFNLGAWGALYAITPEVYPTAMRAGGAGAATAFGRIAAMAAPLVVPLIVGAAGRATLFAVLGAMFAMAMVAAWFLPEYTDQALDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHA0</accession>
    <name>A0A1Q2CHA0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UDP:flavonoid glycosyltransferase YjiC, YdhE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_12010</name>
        <name evidence="2" type="ORF">SAMN05428934_10673</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45435">
        <property type="protein sequence ID" value="AQP45435"/>
        <property type="gene ID" value="RPIT_12010"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92264">
        <property type="protein sequence ID" value="SDY92264"/>
        <property type="gene ID" value="SAMN05428934_10673"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12010"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY92264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="410" mass="42723" checksum="CFB5D5799F2169A3" modified="2017-04-12" version="1">MLILAIGSRGDVQPAAVLAGALKRAGVGARVVGLKEYADVASELGADFVPVDASIADAIGSTRGHLGRLAAGSRPGQAVLLHSWSAAIAGAVSDAVLAALKPGESLLSGVLTRDVASALAGDRKVGTLVFSGLLPTRHAESHFLHNYFTRLDSYNRWGSALGWTMSSSVGLSFGREMRRRLGLPRLGVRRAAVEADRHPIVVAASPTLVPPASDWPANVHQTGFLAAPVPDFQPDDHLAHWLGSGAVYVGFGSMTGGADLDSLTMLSAAARIADRKVVTIAPPGVDPGAVSERVLAVGSVPHAWLFPRCAAVVHHGGSGTTHDGLRAGVPSMAVPHGVDQPYHGWRLQRLGVGPAPLPVRKLSAERLGALLRDFPEDEGFRDRAAQVGERIRSEDGVALTVDHLIGLGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHF1</accession>
    <name>A0A1Q2CHF1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_12585</name>
        <name evidence="2" type="ORF">SAMN05428934_104169</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY79717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12585"/>
    <dbReference type="EnsemblBacteria" id="AQP45537">
        <property type="protein sequence ID" value="AQP45537"/>
        <property type="gene ID" value="RPIT_12585"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY79717">
        <property type="protein sequence ID" value="SDY79717"/>
        <property type="gene ID" value="SAMN05428934_104169"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12585"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY79717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="290" mass="33179" checksum="473833CE9D0CC7ED" modified="2017-04-12" version="1">MDIDTLLDRHGFLSVSEHPRLKHAVAHQVSVGRLVRLLGDSYVEASTAESFELRVAAARQTYPNGVLVRETAARLSWWPELNVPAVQMAQAGAIRRWGFAFERREIPHELKIWNGEHFITNPALTVLDLTDTLGGTAIDEALRRSAVTLDDLRHALDCTPRRRGNRLRARLVAESRDEPWSPLEREAHVMLRRSRVPGWVANHPVEIRGRRYYLDLAVPDLKLAAEIDGWEHHKTLQSFIADREKWNDLALDGWLLLHFTARSLEDLVPQLRQAYAIREAELRSGIRLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHL1</accession>
    <name>A0A1Q2CHL1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2 3">Protein-tyrosine-phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12990</name>
        <name evidence="3" type="ORF">SAMN05428934_10489</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45608">
        <property type="protein sequence ID" value="AQP45608"/>
        <property type="gene ID" value="RPIT_12990"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY77477">
        <property type="protein sequence ID" value="SDY77477"/>
        <property type="gene ID" value="SAMN05428934_10489"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12990"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LMWPc" evidence="1">
        <location>
            <begin position="4"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="LMWPc" evidence="1">
        <location>
            <begin position="142"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY77477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="280" mass="29941" checksum="CAFBF3B3D522ED9F" modified="2017-04-12" version="1">MTRPSVLFVCVHNAGRSQMGAAYTHHLSGGAVEVRSAGSAPADSINPAVRDALLEEGIDISAETPKILTDEAVVASDVVITMGCGDTCPYYPGKRYLDWTLEDPAGQGVASVRPIRDEIKRRVLTLLGELGVEPVELPTPKPTLLFVCVKNGGKSQMAAALARRFGGDAVEVHSAGTHPGSKLNEESARSVEELGATFDGESPKPVDPDVLRRADRVVVIGTEADVQPVEGMRGTIEVWDTVEPSKDGIEGEERMRLVRDDIAARVKALLDDLQSPNLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHM1</accession>
    <name>A0A1Q2CHM1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FHA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_12685</name>
        <name evidence="4" type="ORF">SAMN05428934_104150</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY79160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12685"/>
    <dbReference type="EnsemblBacteria" id="AQP45555">
        <property type="protein sequence ID" value="AQP45555"/>
        <property type="gene ID" value="RPIT_12685"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY79160">
        <property type="protein sequence ID" value="SDY79160"/>
        <property type="gene ID" value="SAMN05428934_104150"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12685"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2320.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022128">
        <property type="entry name" value="FhaA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042287">
        <property type="entry name" value="FhaA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12401">
        <property type="entry name" value="DUF3662"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="153"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY79160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="232" mass="25052" checksum="3F6F731FD12E30FD" modified="2017-04-12" version="1">MGVFDKAEKKIESAVGKVFARAFKGYVHPVEIVAGIQRELDAEAKLLSRDKRLVPNVFTIGLSRNDYDRLAPYAKTLNAEITPSIRDHAADRHYVFNGPVSIDYTLDESLPTGQFTVASQAVADDSSGRKPDRPGKLVLEVNGVRHPLVAPGILIGRGAEADLRLNDPGVSRRHAMISVTGDPAHPVVTIEDLGSTNGVHVNGNRVNKTRIGEGARIEIGNTRMLIHTPAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHN0</accession>
    <name>A0A1Q2CHN0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Stress responsive A/B Barrel Domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12770</name>
        <name evidence="3" type="ORF">SAMN05428934_104133</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY78672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45570">
        <property type="protein sequence ID" value="AQP45570"/>
        <property type="gene ID" value="RPIT_12770"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY78672">
        <property type="protein sequence ID" value="SDY78672"/>
        <property type="gene ID" value="SAMN05428934_104133"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12770"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013097">
        <property type="entry name" value="Dabb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07876">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00886">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51502">
        <property type="entry name" value="S_R_A_B_BARREL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Stress-response A/B barrel" evidence="1">
        <location>
            <begin position="2"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY78672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="99" mass="11022" checksum="B29BEFD77233C360" modified="2017-04-12" version="1">MIRHVVMFKFKADEAPTRGEVANRLRAVLEPLADSVDGVTSLQFGVDDKDIPAHWDAVLISEHTTKEALAAYQQHPDHLEALKVINDLVSTKVVVDYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHQ2</accession>
    <name>A0A1Q2CHQ2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_13215</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13215"/>
    <dbReference type="EnsemblBacteria" id="AQP45649">
        <property type="protein sequence ID" value="AQP45649"/>
        <property type="gene ID" value="RPIT_13215"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13215"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="244"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="315"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="338"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="373"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="401"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="246"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="447" mass="47079" checksum="1749F4E844926061" modified="2017-04-12" version="1">MGVLGALARLWRHAAFRRLMTLRLLSQAADGTLQVGMASYILFSPQSQPNAWAIAGVLALTLMPFTVIGPFVSPLLDRWSRRDVALYSDLARTVLSLIIGAVIFSGATTGAWAVVLFGALLVAMSINRFMLAGLSAGLQHTVEEDEFLTASSIVPTVGPLGVVFGAALAFAARFGLGGFMPSHQADAVVFGIAALGFLGSVLVCKGFSRRALGPTVPAERTSWVTVAVGLVEAARHVRQQTPAALALILMGATRLLFGLLSVAVILAARNLWHSVDQPDAALADLAIWGGLTGVGFVLSAPFVPLLVRAMGLRRTALLLLIGAAVVSALTALSTDKWVLFVASFFLGLAVQSFKICVDTIVQSHVDERYKGRAFTFYDMIFNSAFVLAGVVAALTLPPTGLSAPAFLLIALGYALCAVVLWVVAARLGNTTLERGTEDLTQGSLRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHS3</accession>
    <name>A0A1Q2CHS3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">K(+)-insensitive pyrophosphate-energized proton pump</fullName>
            <ecNumber evidence="9">7.1.3.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Membrane-bound proton-translocating pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Pyrophosphate-energized inorganic pyrophosphatase</fullName>
            <shortName evidence="9">H(+)-PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hppA</name>
        <name evidence="11" type="ORF">RPIT_13065</name>
        <name evidence="12" type="ORF">SAMN05428934_10474</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>diphosphate + H(+)(in) + H2O = 2 H(+)(out) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:13973"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="7.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="7.1.3.1" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13065"/>
    <dbReference type="EnsemblBacteria" id="AQP45623">
        <property type="protein sequence ID" value="AQP45623"/>
        <property type="gene ID" value="RPIT_13065"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY77050">
        <property type="protein sequence ID" value="SDY77050"/>
        <property type="gene ID" value="SAMN05428934_10474"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13065"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009678">
        <property type="term" value="F:pyrophosphate hydrolysis-driven proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01129">
        <property type="entry name" value="PPase_energized_pump"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004131">
        <property type="entry name" value="PPase-energised_H-pump"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31998">
        <property type="entry name" value="PTHR31998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03030">
        <property type="entry name" value="H_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001265">
        <property type="entry name" value="H+-PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="5 9" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544516" description="K(+)-insensitive pyrophosphate-energized proton pump" evidence="10">
        <location>
            <begin position="41"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="370"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="574"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="606"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="676"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="700"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="767"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="791"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="site" description="Determinant of potassium independence" evidence="9">
        <location>
            <position position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP45623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY77050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="839" mass="88617" checksum="6D772F450967B22D" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHU0</accession>
    <name>A0A1Q2CHU0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ubiquinone/menaquinone biosynthesis C-methylase UbiE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_13180</name>
        <name evidence="5" type="ORF">SAMN05428934_10451</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY76421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13180"/>
    <dbReference type="EnsemblBacteria" id="AQP45643">
        <property type="protein sequence ID" value="AQP45643"/>
        <property type="gene ID" value="RPIT_13180"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY76421">
        <property type="protein sequence ID" value="SDY76421"/>
        <property type="gene ID" value="SAMN05428934_10451"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13180"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004033">
        <property type="entry name" value="UbiE/COQ5_MeTrFase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01209">
        <property type="entry name" value="Ubie_methyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0830">Ubiquinone</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY76421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="237" mass="25953" checksum="DE12DD443A75EE3E" modified="2017-04-12" version="1">MSATSDAFDRGAGRYDLMVSLNPGYHHELGRASRELSARLKGREGLSLIDLACGSGASTRTLVEATPPGTRITGIDASAGMLAEARSKPWPPEVRFTQASAGRLDVSAFGEHDGVQACYLLRNVPEQERDRAVDEIFSLLRPGGWAVFQEYSVRGNARATAVWSAVASAIIIPLGWIIDRNPDLYRYLHRSVLEFDDVATVADRLTRAGFVDVAHRTASGWQRGILHTFVCRKPKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHU2</accession>
    <name>A0A1Q2CHU2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13165</name>
        <name evidence="4" type="ORF">SAMN05428934_10454</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY76505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45640">
        <property type="protein sequence ID" value="AQP45640"/>
        <property type="gene ID" value="RPIT_13165"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY76505">
        <property type="protein sequence ID" value="SDY76505"/>
        <property type="gene ID" value="SAMN05428934_10454"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13165"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="10"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY76505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="195" mass="21774" checksum="17F50C9988CA558D" modified="2017-04-12" version="1">MTEPNTSRREATKARLVSAGIAEFARRGIDATSVEQLCEAAGFTRGAFYSNFDSKDDLCIEITRRIATGTAEALQQALDEMPAAMERGEMVRYLLASRSPSPEVRTTLMEMELRAHRDPAFGVRFQEARSDLWPAHIEMARLAAERAGVDYTIDVRDFMFISEATYYYPGGSDDPERPARLIGLLAEAFSHPKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHX7</accession>
    <name>A0A1Q2CHX7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chromosome partitioning protein ParB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Chromosome partitioning protein, ParB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_13565</name>
        <name evidence="5" type="ORF">SAMN05428934_11186</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ParB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ13140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13565"/>
    <dbReference type="EnsemblBacteria" id="AQP45711">
        <property type="protein sequence ID" value="AQP45711"/>
        <property type="gene ID" value="RPIT_13565"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ13140">
        <property type="protein sequence ID" value="SDZ13140"/>
        <property type="gene ID" value="SAMN05428934_11186"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13565"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041468">
        <property type="entry name" value="HTH_ParB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004437">
        <property type="entry name" value="ParB/RepB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17762">
        <property type="entry name" value="HTH_ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00180">
        <property type="entry name" value="parB_part"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="3">
        <location>
            <begin position="34"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ13140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="294" mass="32148" checksum="6B1DBDD54F3DC21D" modified="2017-04-12" version="1">MAARHSGLGKGLGDLFAKTDDEGDVALSDGSVFLEIPVDQVQPNPQQPRTVFDEDELGELAESIAEFGVLQPVVVRRAGRDAFELIMGERRLRASKIAGRATIPAIVRGTDDTALLRDALLENLHRANLNPLEEAHAYQQLLEDFACTKEELSQRIHRSRPQISNTLRLLNLPARVQSKVAAGVLSAGHARALLGLDDPELQEHLAERIVAEGLSVRSTEEIVAMGRGTGVRRSASRAPRTPSDREREIAGHLSDHFDTRVKVNIGRNKGKITIEFASGDDLERIMAILDGKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHZ2</accession>
    <name>A0A1Q2CHZ2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_13705</name>
        <name evidence="2" type="ORF">SAMN05428934_11158</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45732">
        <property type="protein sequence ID" value="AQP45732"/>
        <property type="gene ID" value="RPIT_13705"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12685">
        <property type="protein sequence ID" value="SDZ12685"/>
        <property type="gene ID" value="SAMN05428934_11158"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13705"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ12685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="98" mass="10379" checksum="31D3303814BE94F5" modified="2017-04-12" version="1">MKTLSSDTGVADLIAVYSMRELLLRRRRHLTVRIASTHPELTIATPRGDIALELTGGQWLITGPSGRGVLVEQDPGECASAVVALVDATTAPRLDATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI64</accession>
    <name>A0A1Q2CI64_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13790</name>
        <name evidence="3" type="ORF">SAMN05428934_11142</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13790"/>
    <dbReference type="EnsemblBacteria" id="AQP45745">
        <property type="protein sequence ID" value="AQP45745"/>
        <property type="gene ID" value="RPIT_13790"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12374">
        <property type="protein sequence ID" value="SDZ12374"/>
        <property type="gene ID" value="SAMN05428934_11142"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13790"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ12374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="447" mass="48420" checksum="0898C714A14BC2CD" modified="2017-04-12" version="1">MNIRTVRGLGGLITGLILLVVFSVLLTRAMDTTSYNTWGALIWAPLIIGVNLWLISIAMRNEPDRWVVRLVYIGYAAKLVGIAARYFTIFVLYDGVGDASRYNLYAARWYFEWRRGVFEVSGDGKFGTHNTELITTAVYTVVGPSPIVGFLVFGTLAFWGCVLLFKAFQAAVPEGNFRRYAILVLLLPSLLFWPSSIGKEAFLLFGVGLTGLGAAKFFNRRIVAGLGYLTAGLVATSLIRPHLTVLLLSSLFVALLLRRGSGTPTSFLGKTVGLALVAAASVLAITQAADVLGIEDLTAEEVTGEIDWASGQTDTGGSAFVPVPLSSPLGLPAAIITLLFRPFPWEASSGLVALQSLEGIALLLLAIVGWRRLAQVPRLLRRNAWVVFAAVYVLAFILAFAGFANFGIVARQRSLMIPFFLALLALPDPRRPHNALTDSEERQLANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIA3</accession>
    <name>A0A1Q2CIA3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Luciferase family oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Luciferase family oxidoreductase, group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_14440</name>
        <name evidence="4" type="ORF">SAMN05428934_109128</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">To bacterial alkanal monooxygenase alpha and beta chains.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ07045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14440"/>
    <dbReference type="EnsemblBacteria" id="AQP45858">
        <property type="protein sequence ID" value="AQP45858"/>
        <property type="gene ID" value="RPIT_14440"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ07045">
        <property type="protein sequence ID" value="SDZ07045"/>
        <property type="gene ID" value="SAMN05428934_109128"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14440"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019949">
        <property type="entry name" value="Luciferase_OxRdatse_group-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03558">
        <property type="entry name" value="oxido_grp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ07045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="355" mass="38513" checksum="B939F2123DCC2BBC" modified="2017-04-12" version="1">MKLSVLDLINVRQGQTTAQALRASRAMVEAADKLGYTRYWVAEHHNTTSVASTAPAVELMYLGQDTSRIRLGSGGVMLPNHSPLAVAEQFALLAAVYGDRIDLGIGRAPGTDPITSAAIRGHLSGGHFVDANGRPSDPVREFPQNVADILTLLNPDGAEIRLRHGQHYSLRATPVLEHAPAVWLLGSSDYSAEMAATMGLPYVFAHHFSGRGTQRALDLYRSSFQPSEHGAQPRTFVTVNVSVAETADEAWELCEPHQYLMASLSTRGKMDPQPRVGDEVKRLLTDDLRAAVAPVVDTWAIGNPEQVKAQLEETADQYGVDEIMIHPIEGAYEADPADAWPAKLRGLELLAEALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIG4</accession>
    <name>A0A1Q2CIG4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oligopeptide transport system ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Peptide ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_14715</name>
        <name evidence="7" type="ORF">SAMN05428934_10977</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14715"/>
    <dbReference type="EnsemblBacteria" id="AQP45902">
        <property type="protein sequence ID" value="AQP45902"/>
        <property type="gene ID" value="RPIT_14715"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06062">
        <property type="protein sequence ID" value="SDZ06062"/>
        <property type="gene ID" value="SAMN05428934_10977"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14715"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="7"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="50"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ06062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="336" mass="37267" checksum="A916E853C878FD14" modified="2017-04-12" version="1">MSEDIILRGTDLKKHYPIKKGVLRRTVGHVKAVDGVSFELRRGETLGVVGESGCGKSTLGRLLVQLEEPTEGFVEMEGRQIKAGAEMRRARRDIQIVFQDPYTSLNPRMTVGDIIAEPLRIHKDELDLKGGERRRVQELLDQVGLNPEHINRYPHQFSGGQRQRIGIARGIALNPKVLVCDEPVSALDVSVQAQVVNLFERLQRELGLSYVFIAHDLAVVRHISHRVAVMYLGQMVEVGEKDQIYGSPMHPYTQALMSAAPVPDPVQQAKRERIVLVGDVPSPANPPSGCRFHTRCWKAQEICATKTPLLEIKGEGADAHPAACHFAEPMAEVVHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CII5</accession>
    <name>A0A1Q2CII5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA-binding transcriptional regulator, MerR family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">MerR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14785</name>
        <name evidence="3" type="ORF">SAMN05428934_10963</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45914">
        <property type="protein sequence ID" value="AQP45914"/>
        <property type="gene ID" value="RPIT_14785"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05778">
        <property type="protein sequence ID" value="SDZ05778"/>
        <property type="gene ID" value="SAMN05428934_10963"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14785"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00552">
        <property type="entry name" value="HTH_MERR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="5"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ05778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="125" mass="13722" checksum="B0DBDE695065AE69" modified="2017-04-12" version="1">MNEPTLQIGAVAEQTGLSVRTLRHYEDVGLVRPSARSAGGFRLYTADDVARLLLIRRMKPLGFTLEEMGRLLATANAHLTEPTEQTAAELNAYVQEASARRDELLRQVALADEYLAQLQALGVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CII6</accession>
    <name>A0A1Q2CII6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01045"/>
    <dbReference type="EnsemblBacteria" id="AQP45946">
        <property type="protein sequence ID" value="AQP45946"/>
        <property type="gene ID" value="RPIT_01045"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01045"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="259" mass="26406" checksum="7B8B140448D12710" modified="2017-04-12" version="1">MLRSEWIKLASVPSTMLAFAGILVIGLGGSLFLALTLESSGVPSVPSVERTMGDVTMPMVILGQIIAGISGVTASGSEYSSGSIHTTLMAVPARLRVLWAKAIVQFAAVTSVALITVVGAWLCTYPAYAEYGLEAPATAPGVLVALLGSAVYLGMCAVFGVGVGMLVRSTSVGVIVVFAATLLGPILASALPFNLFSRVARVLLLGNAGDAMARVGTPDGPFLDVWGGHVSTGAGWLLASGWVILALALGAYALRSRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIK9</accession>
    <name>A0A1Q2CIK9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aminoglycoside O-phosphotransferase APH(3'')-Ib</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Streptomycin 3-kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_14600</name>
        <name evidence="8" type="ORF">SAMN05428934_10994</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the aminoglycoside phosphotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_001082319.1">
        <property type="nucleotide sequence ID" value="NZ_FNPU01000009.1"/>
    </dbReference>
    <dbReference type="SMR" id="A0A1Q2CIK9"/>
    <dbReference type="STRING" id="1610493.RPIT_14600"/>
    <dbReference type="EnsemblBacteria" id="AQP45885">
        <property type="protein sequence ID" value="AQP45885"/>
        <property type="gene ID" value="RPIT_14600"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06393">
        <property type="protein sequence ID" value="SDZ06393"/>
        <property type="gene ID" value="SAMN05428934_10994"/>
    </dbReference>
    <dbReference type="GeneID" id="60604314"/>
    <dbReference type="GeneID" id="66341467"/>
    <dbReference type="KEGG" id="tfl:RPIT_14600"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05150">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024165">
        <property type="entry name" value="Kan/Strep_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000706">
        <property type="entry name" value="Kanamycin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="6">
        <location>
            <begin position="17"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000706-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000706-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ06393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="267" mass="29587" checksum="2E7486D96B8E3090" modified="2017-04-12" version="1">MNRTNIFFGESHSDWLPVRGGESGDFVFRRGDGHAFAKIAPASRRGELAGERDRLIWLKGRGVACPEVINWQEEQEGACLVITAIPGVPAADLSGADLLKAWPSMGQQLGAVHSLSVDQCPFERRLSRMFGRAVDVVSRNAVNPDFLPDEDKSTPQLDLLARVERELPVRLDQERTDMVVCHGDPCMPNFMVDPKTLQCTGLIDLGRLGTADRYADLALMIANAEENWAAPDEAERAFAVLFNVLGIEAPDRERLAFYLRLDPLTWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIM6</accession>
    <name>A0A1Q2CIM6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Elongation factor G</fullName>
            <shortName evidence="6">EF-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fusA</name>
        <name evidence="8" type="ORF">RPIT_02960</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02960"/>
    <dbReference type="EnsemblBacteria" id="AQP45986">
        <property type="protein sequence ID" value="AQP45986"/>
        <property type="gene ID" value="RPIT_02960"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02960"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00054_B">
        <property type="entry name" value="EF_G_EF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="1"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="2"/>
            <end position="9"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="66"/>
            <end position="70"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="120"/>
            <end position="123"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="682" mass="75258" checksum="C4B30E9992D18426" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIR0</accession>
    <name>A0A1Q2CIR0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03560"/>
    <dbReference type="EnsemblBacteria" id="AQP45997">
        <property type="protein sequence ID" value="AQP45997"/>
        <property type="gene ID" value="RPIT_03560"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03560"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025445">
        <property type="entry name" value="DUF4191"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13829">
        <property type="entry name" value="DUF4191"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="232" mass="25495" checksum="C5DBB896D35E5C66" modified="2017-04-12" version="1">MKEAKKNSTNPADWGRWRQLTETYKVTAQYDKQLPWFMIGSFVLVFALLLVVGFLLDSPLIWGILGVSAGLLAAMGIFAIRARKAIYRRYEGQAGSAEVALQMLPKKWVSTPVITATRHMDAVHRTIGPGGLVLIGEGDPGRLRPLLASEKRKHEQVAYGVEVKTIQMGKGAGQVPLDKLADHIKKLPKSLTPAKIVEVNQRLRALDAMRPKAPIPKGVINTKGARSAMRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIT5</accession>
    <name>A0A1Q2CIT5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 20">Methionine synthase</fullName>
            <ecNumber evidence="6 20">2.1.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19 20">5-methyltetrahydrofolate--homocysteine methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="31" type="ORF">RPIT_06120</name>
    </gene>
    <organism evidence="31 32">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="31 32" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="31 32">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18 20">Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 20">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:11172"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="2.1.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 20 23">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 20 22">
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 20">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetH route): step 1/1.</text>
    </comment>
    <comment type="domain">
        <text evidence="20">Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the vitamin-B12 dependent methionine synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.13" evidence="6 20"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06120"/>
    <dbReference type="EnsemblBacteria" id="AQP46046">
        <property type="protein sequence ID" value="AQP46046"/>
        <property type="gene ID" value="RPIT_06120"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06120"/>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00081"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008705">
        <property type="term" value="F:methionine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042558">
        <property type="term" value="P:pteridine-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02069">
        <property type="entry name" value="methionine_synthase_B12_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.196.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003759">
        <property type="entry name" value="Cbl-bd_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
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        <property type="entry name" value="Dihydropteroate_synth-like"/>
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        <property type="entry name" value="HCY_dom"/>
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        <property type="entry name" value="HCY_dom_sf"/>
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        <property type="entry name" value="Met_synthase_B12-bd"/>
    </dbReference>
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        <property type="entry name" value="MetH"/>
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        <property type="entry name" value="Meth_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
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    <dbReference type="InterPro" id="IPR004223">
        <property type="entry name" value="VitB12-dep_Met_synth_activ_dom"/>
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        <property type="entry name" value="VitB12-dep_Met_synth_activ_sf"/>
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        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02965">
        <property type="entry name" value="Met_synt_B12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02574">
        <property type="entry name" value="S-methyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000381">
        <property type="entry name" value="MetH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01018">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF47644"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82282">
        <property type="entry name" value="SSF82282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02082">
        <property type="entry name" value="metH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50974">
        <property type="entry name" value="ADOMET_ACTIVATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51337">
        <property type="entry name" value="B12_BINDING_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50970">
        <property type="entry name" value="HCY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 20" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 20 22" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="17 20 21" id="KW-0170">Cobalt</keyword>
    <keyword evidence="13 20 21" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16 20" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="8 20 24" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="32" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0677">Repeat</keyword>
    <keyword evidence="12 20 22" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="11 20 24" id="KW-0808">Transferase</keyword>
    <keyword evidence="15 20 21" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Hcy-binding" evidence="26">
        <location>
            <begin position="1"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Pterin-binding" evidence="27">
        <location>
            <begin position="335"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding N-terminal" evidence="30">
        <location>
            <begin position="627"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding" evidence="29">
        <location>
            <begin position="721"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="domain" description="AdoMet activation" evidence="28">
        <location>
            <begin position="867"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Methylcob(III)alamin binding" evidence="22">
        <location>
            <begin position="731"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="25">
        <location>
            <begin position="858"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="22">
        <location>
            <begin position="1151"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="25">
        <location>
            <begin position="860"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="binding site" evidence="21 23">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21 23">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21 23">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="21">
        <location>
            <position position="734"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
        <ligandPart>
            <name>Co</name>
            <dbReference type="ChEBI" id="CHEBI:27638"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="779"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="837"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="914"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="1097"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00025552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00031040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRNR" id="PIRNR000381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PIRSR" id="PIRSR000381-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS50970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="PROSITE" id="PS50974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="29">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="30">
        <source>
            <dbReference type="PROSITE" id="PS51337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="31">
        <source>
            <dbReference type="EMBL" id="AQP46046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="32">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="1155" mass="125213" checksum="58DF2AAA758D6EB6" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIU1</accession>
    <name>A0A1Q2CIU1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_05255</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05255"/>
    <dbReference type="EnsemblBacteria" id="AQP46031">
        <property type="protein sequence ID" value="AQP46031"/>
        <property type="gene ID" value="RPIT_05255"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05255"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021412">
        <property type="entry name" value="DUF3052"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11253">
        <property type="entry name" value="DUF3052"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP46031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="142" mass="15518" checksum="0A8BE90CE00688F2" modified="2017-04-12" version="1">MWQAWSVDTEGLTGAELLALEPGLVVQELGWDEDVDADLRDDIMDAIDAEMVDEPLEAVDVVILWWRDDDGDVADGLVDAMTDLTDKGIIWLLTPKVGRSGFIDPSSVAEGVTIAGLSLTRTANVAPDWQATKVVRPKNTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIY5</accession>
    <name>A0A1Q2CIY5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTPase HflX</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP-binding protein HflX</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hflX</name>
        <name evidence="8" type="ORF">RPIT_07045</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer. Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">May associate with membranes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07045"/>
    <dbReference type="EnsemblBacteria" id="AQP46064">
        <property type="protein sequence ID" value="AQP46064"/>
        <property type="gene ID" value="RPIT_07045"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07045"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01878">
        <property type="entry name" value="HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00900">
        <property type="entry name" value="GTPase_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030394">
        <property type="entry name" value="G_HFLX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032305">
        <property type="entry name" value="GTP-bd_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016496">
        <property type="entry name" value="GTPase_HflX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025121">
        <property type="entry name" value="GTPase_HflX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042108">
        <property type="entry name" value="GTPase_HflX_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10229">
        <property type="entry name" value="PTHR10229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16360">
        <property type="entry name" value="GTP-bdg_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13167">
        <property type="entry name" value="GTP-bdg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03156">
        <property type="entry name" value="GTP_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51705">
        <property type="entry name" value="G_HFLX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hflx-type G" evidence="7">
        <location>
            <begin position="246"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP46064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="465" mass="50284" checksum="E5081BCD264DA005" modified="2017-04-12" version="1">MEDFDPDLPDDDGEQEDLAARNSLRRVAGLRTELEDVTEVEYRQLRLERVVLVSVWTSGTQEDADNAMAELKLLAETAGSEVLAGLVQRRSHPDPATYVGRGKVEEVAEAVRATGADTVICDGELEPAQLRNLEDRVKVKVVDRTALILDIFAQHAKSAEGKAQVELAQLQYLKQRLRGWGGNLSRQAGGRAAGGAGIGGRGPGETKIETDRRRIHTRIAQLRRKLREMDATREGKRAERRRNQVPSVAIVGYTNAGKSSLLNRLTGAGVLVEDALFATLDPTTRRSETSDGRVFTLTDTVGFVRHLPHDLVEAFRSTLEESAQADLLVHVVDASDSDPEGQIAAVRTVLTEIGASTVPELLVLNKADLADEATILALRANHPGAVVISARTGAGLDELRTTIEDRLPQPEVAVDVVVPYDRGDLVDKIHKTAVIGSLEHTAEGTAIVANVRADLADELAAFARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ10</accession>
    <name>A0A1Q2CJ10_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_06985</name>
        <name evidence="2" type="ORF">SAMN05428934_11048</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06985"/>
    <dbReference type="EnsemblBacteria" id="AQP46063">
        <property type="protein sequence ID" value="AQP46063"/>
        <property type="gene ID" value="RPIT_06985"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09023">
        <property type="protein sequence ID" value="SDZ09023"/>
        <property type="gene ID" value="SAMN05428934_11048"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06985"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP46063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ09023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="299" mass="32566" checksum="EDBF28486009ED01" modified="2017-04-12" version="1">MTDYAHFDFDATQRGAWDEFTLRLDEVLSVMDSSADLTISVDAPAGVEPRPGIRFSMGEGASVRAFVTGSAAGLPTPEEARLLAELGWTRDDDTTFHAEADQEAVAALAELATRTLSTVFGVVHPVFLEPDQLSEILQGHAPWVPLTPRKLSRKEKAVMPGNRKELDQLVDDELRRAFGHPPLRTIQGDVAIRVGSTMVLCRSTPDAAELVLFSPLVHDVVGRSRACEVLNDLNVESRYGRFALHRDRVFVQLSVPTQPFVPAHLHQALAALSKIADGIDDELATKLGGRTTFGPGPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ26</accession>
    <name>A0A1Q2CJ26_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_09350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09350"/>
    <dbReference type="EnsemblBacteria" id="AQP46104">
        <property type="protein sequence ID" value="AQP46104"/>
        <property type="gene ID" value="RPIT_09350"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09350"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031009">
        <property type="entry name" value="Tcm_partner"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04474">
        <property type="entry name" value="tcm_partner"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP46104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="385" mass="43684" checksum="B8B1A5391BB9B24F" modified="2017-04-12" version="1">MLREYTKVFASVVGSQDRTRPVWVIDGYAGAGAYEEPDPEGAHPDGSPLIVLKMAEEFKSRQVIKSIFIESDTSAVEALDKNVTPFRDRGLSASILNGTVEEQMPSAWSAVGTNPVVTFLDPFGVAMRRETMTRLLLSRTRDLPPSEVLLNINLEAVWRIGGNLELSAGRVVPCKGQERGVERVDRFFGGTAWRQTFHDMRHEHGSAAQAAEHVIAVYRDQIRQDTGYDSMSIPVRRRPHHEPLFLLTLFFRHPVGGYKFADAACRATRKWRETYRKQELEEFLGRQRQESLFGDDFEMENAAKEGARQEQELDAQWVQNICDNIRNLGAHRLDVARDVSLILGHTLGLAGERHIRKAWDQLAEDGYLRPRDTSKKMHRSAMERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ57</accession>
    <name>A0A1Q2CJ57_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_11150</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11150"/>
    <dbReference type="EnsemblBacteria" id="AQP46134">
        <property type="protein sequence ID" value="AQP46134"/>
        <property type="gene ID" value="RPIT_11150"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11150"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904823">
        <property type="term" value="P:purine nucleobase transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045018">
        <property type="entry name" value="Azg-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337">
        <property type="entry name" value="PTHR43337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="480"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP46134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="504" mass="52345" checksum="81006E1D4BC85693" modified="2017-04-12" version="1">MHPETQPSGSKLDGYFEITKRHSTVSREVRGGLVTFFAMAYIIALNPLIIGTAVDKDGRLISGAPKFLDAAMTQVDNAAVGASIGMVAAATALVAGLLTIAMGVIGRFPIGLAAGLGLNALVAYVLAPQMTWPQAMGLVVWEGILIAILVLTGFRTAVFRAIPRTLRTAISVGIGLFITFVGFVNAGVVRKAAGTPVELGINGSLQGWPIAVFFIGIMVLIALHVLKVKGAMLLSIVVATVVAIVVEATAKIGPQVTADGANPFGWSLNVPSLANFTLPDLGLIGRVDMVGAFFVDGEFQFTRLLALAVLVFSLLLADFFDTMGTVVAVGSEGDLLDEHGMPPRTTEILLVDSVAAAAGGLGSVSSNTCYIESTAGVGEGARTGLASVVTGLAFLLAIFLSPIINLVPSEAAAPVLVFVGFLMISQVVDVDWNDPEVGIPAFLTMVLMPFAYSITVGIGAGFLAHVFIKLVRGHGKQVHPLMYVVAGLFVIYFVQGALLGLIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ59</accession>
    <name>A0A1Q2CJ59_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13210"/>
    <dbReference type="EnsemblBacteria" id="AQP46166">
        <property type="protein sequence ID" value="AQP46166"/>
        <property type="gene ID" value="RPIT_13210"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13210"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00359">
        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="389" mass="42799" checksum="4C1D58FCA9100380" modified="2017-04-12" version="1">MRRDDPQGPRLERTGSVVRIRSLAAGRQLLRERHRTTQAGFTAEKIPKGFLKHHPILISDGPLHDEQRTKVGRFFAPKVVAERYPGLMADSADRLLAGVEGELLLDDLALLYSVEVTAKVVGLTESPVEKMAGRLTTFFNQPPFDITKPDLGRTGKQWAAAAVNGLVPVARFYVRDVRPAVRARRKEPRGDVISHLIAEGYTNADILIECVTYGTAGMVTTREFICMAAWHLLTDEDLRSRYEAGEERDRIAVLNEIIRLEPVVGHLYRRVQESFSIEDGSDSMNLEPGDLVDVCVRDANVDPEAVGSDALSLCPARNLPRGVDAAALTFGDGAHRCPGQPLALLEADALLTRLLALNPRIVSEPELGWDDLIAGYTLRGFRLALALNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CB87</accession>
    <name>A0A1Q2CB87_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43412">
        <property type="protein sequence ID" value="AQP43412"/>
        <property type="gene ID" value="RPIT_00050"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00050"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012569093" evidence="2">
        <location>
            <begin position="24"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="262" mass="26510" checksum="4D1F7F6C3D67D1AB" modified="2017-04-12" version="1">MVALSAGLVAAFGLVGGGLNALADEHDGPEANKASYWENYFGVAGIECEKYEPVSTPYTVPTAQEGYDWYAAILKAGSENSNDEGTPTNQVIRPISDGQVLNHVSGKKISHVILCWVPEPTMSPSPTPTVTATPTVTATPTVTATPTMTATPTVTATPTATVKPTVTATPTATATPTVTATPTATVKPTVTATPTATATPTATATPTVTATATVTPTMTSSPTMTSKPTATSKPSATSKPTATSKPTVKSTYRGVGLPSAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBD3</accession>
    <name>A0A1Q2CBD3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase, MGT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00115</name>
        <name evidence="3" type="ORF">SAMN05428934_10922</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ04949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00115"/>
    <dbReference type="EnsemblBacteria" id="AQP43423">
        <property type="protein sequence ID" value="AQP43423"/>
        <property type="gene ID" value="RPIT_00115"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ04949">
        <property type="protein sequence ID" value="SDZ04949"/>
        <property type="gene ID" value="SAMN05428934_10922"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00115"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006326">
        <property type="entry name" value="UDPGT_MGT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01426">
        <property type="entry name" value="MGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_tran_28_C" evidence="1">
        <location>
            <begin position="275"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ04949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="389" mass="41537" checksum="8A7C76313A181971" modified="2017-04-12" version="1">MARILVAGLPAFGLANPSLPLIRALVDGGHHVDVLQGEAFRGGVERAGATLLPFGFYLDGALTEPRQLIRYGRRLFADMAAAMITLGPRYDALIGTGMQPHLTEVERAVDRPVIFASPVFFQNDRTARHFADIAVGLPAPVRRLLRTPALRRVAGAGAGAAVFGTDVGDIIDLLGMRSSSLNLTVATREYQPYPDDFPGGVFLGPTPTQRRPDPEFPIERVRGHDGPVIYGTLGTVFNTWTPFFRTLADAFAGTDALVVLTTGSREGLARLGEVPENVIARSFVPQTEILERADVCFTHGGFGTATDAVSLGVPPVLTPMGADQFFNAYRLAELGAGVVLPRREFTVEAVRAAADTARHGDRSGLERLRQSFASAGGPALGVRAIESVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBD4</accession>
    <name>A0A1Q2CBD4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">von Willebrand factor type A domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_00085</name>
        <name evidence="5" type="ORF">SAMN05428934_10928</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00085"/>
    <dbReference type="EnsemblBacteria" id="AQP43417">
        <property type="protein sequence ID" value="AQP43417"/>
        <property type="gene ID" value="RPIT_00085"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05094">
        <property type="protein sequence ID" value="SDZ05094"/>
        <property type="gene ID" value="SAMN05428934_10928"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00085"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544395" evidence="2">
        <location>
            <begin position="24"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="3">
        <location>
            <begin position="392"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="655"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="717"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ05094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="755" mass="80395" checksum="58D8B17676D504E2" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBH4</accession>
    <name>A0A1Q2CBH4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-amylase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Glycosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00400</name>
        <name evidence="3" type="ORF">SAMN05428934_10534</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY84334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00400"/>
    <dbReference type="EnsemblBacteria" id="AQP43463">
        <property type="protein sequence ID" value="AQP43463"/>
        <property type="gene ID" value="RPIT_00400"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY84334">
        <property type="protein sequence ID" value="SDY84334"/>
        <property type="gene ID" value="SAMN05428934_10534"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00400"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="1">
        <location>
            <begin position="9"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY84334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="391" mass="43136" checksum="5AD83C5CFEBB1898" modified="2017-04-12" version="1">MLEHAVWWHVYPLGALGAPIRGEHGAPEPRLRRLEAWLDYAVELGCNGLLLNPVFASVAHGYETLDHYRIDPRLGDTEDFDALVAAAASRGLHVVLDGVFNHVAREHPLVAARPDMIRWQGDQPKGWEGHSDLVELNHDHPEVRAMVADIMAHWLRRGVAGWRLDVAYAVPADFWRDVLGRVRAEFPSAIFLGEVIHGDYAVIARDSTFDSVTQYELWKAIWSSLVDRNGWELAHAIERHAAFSAEFIPNTFTGNHDVSRMASLVEPHQLPITPYLLTTLPGAPSVYYGDEQGFTGLKTDRLGGDDDVRPPLPASPADLSALGAGMLHHYQAAIALRRRNPWLATADVEVTRRANEAISYRVTGSGNTLDVHIDLVGGGVTIEGSGEHLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBJ5</accession>
    <name>A0A1Q2CBJ5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00475</name>
        <name evidence="2" type="ORF">SAMN05428934_10549</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY84738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43478">
        <property type="protein sequence ID" value="AQP43478"/>
        <property type="gene ID" value="RPIT_00475"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY84738">
        <property type="protein sequence ID" value="SDY84738"/>
        <property type="gene ID" value="SAMN05428934_10549"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00475"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY84738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="131" mass="13933" checksum="B04212185B6DE9F9" modified="2017-04-12" version="1">MTWRIEVEADSGEPIELAFAMTAPVEDRSMLVLVDPQPQVIHEKVIPVDMPFSEQLNAHFVYLPAGPPGVTLITVKFSRAIAGLSVDLVSWPTAVASGADVCAGVMATILPDLAHGRPLATSTTARWVVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBK9</accession>
    <name>A0A1Q2CBK9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS110 family transposase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00540</name>
        <name evidence="3" type="ORF">RPIT_13390</name>
        <name evidence="4" type="ORF">SAMN05428934_10561</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY85039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43490">
        <property type="protein sequence ID" value="AQP43490"/>
        <property type="gene ID" value="RPIT_00540"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45680">
        <property type="protein sequence ID" value="AQP45680"/>
        <property type="gene ID" value="RPIT_13390"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY85039">
        <property type="protein sequence ID" value="SDY85039"/>
        <property type="gene ID" value="SAMN05428934_10561"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00540"/>
    <dbReference type="KEGG" id="tfl:RPIT_13390"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="1">
        <location>
            <begin position="12"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY85039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="348" mass="38306" checksum="F43B13B6784FFF6C" modified="2017-04-12" version="1">MTIVADIYPYVVGVDTHARSHTFAILSRGRLVDTQTFPTNQAGLARAVDWIGRRTAGEISDTVVSAEGTSSYGAQLAGMLAEHGYRVVEAPTPHRGRDGKTDALDAQRAARGVIDLEDTALRDHRRHGDLRDAIAALSTLRAHYTDQRTALINMLTALLRVTDLGIDARGPLTATQITQIAGWRPRREPEPLHIQRQIAIAHARDIGDLDRRLAANKSQLADLTARHSPQLLDIYGVGPVSAAVIIAAWSHPGRVRSEAAFAKLAGVCPIPASSGNTTRHRLNRGGDRRLNWALHQIITTRLSHDPRTKAYVARREAEGKTPKEIRRCLKRYLARQIYRTLTAPLDNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBR2</accession>
    <name>A0A1Q2CBR2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00825</name>
        <name evidence="3" type="ORF">SAMN05428934_105118</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00825"/>
    <dbReference type="EnsemblBacteria" id="AQP43540">
        <property type="protein sequence ID" value="AQP43540"/>
        <property type="gene ID" value="RPIT_00825"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86555">
        <property type="protein sequence ID" value="SDY86555"/>
        <property type="gene ID" value="SAMN05428934_105118"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00825"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY86555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="153" mass="16249" checksum="83027B1780E430FD" modified="2017-04-12" version="1">MEPRLNFVTLAVTDIAAARRFYIEGLGWPAEFEAESIVMIRLSATLVLSLWAEDEFEAEVGPISRGDGLVPITLAHNVPAPADVDRVLADADAAGASDIVPGQSRAWGGYSGYFADPDGIRWEVAHNPSTLGVDLMRASGLLPRDTQAGGSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC22</accession>
    <name>A0A1Q2CC22_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_01130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43595">
        <property type="protein sequence ID" value="AQP43595"/>
        <property type="gene ID" value="RPIT_01130"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01130"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="134" mass="14808" checksum="8F302AC4A17FC932" modified="2017-04-12" version="1">MSASRRDRWSNSFEPELRGLLSEFPTMSASVIAERIGWQHLASLLRTRDAAFRPLYAPPDPSDRTEYRPGEIVQCDLWFPAKVVPVGPGVLVAPPVLTTTAAWSGFIAALLLPTRQSSALLAGMWQLRYEAGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC40</accession>
    <name>A0A1Q2CC40_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thiamine ABC transporter substrate-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Thiamine transport system substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01635</name>
        <name evidence="3" type="ORF">SAMN05428934_10875</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01635"/>
    <dbReference type="EnsemblBacteria" id="AQP43671">
        <property type="protein sequence ID" value="AQP43671"/>
        <property type="gene ID" value="RPIT_01635"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02351">
        <property type="protein sequence ID" value="SDZ02351"/>
        <property type="gene ID" value="SAMN05428934_10875"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01635"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030975">
        <property type="term" value="F:thiamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015888">
        <property type="term" value="P:thiamine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13545">
        <property type="entry name" value="PBP2_TbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005948">
        <property type="entry name" value="ThiB-like"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01254">
        <property type="entry name" value="sfuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544409" evidence="1">
        <location>
            <begin position="27"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ02351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="347" mass="37375" checksum="BE9AFD3E4EEB80E1" modified="2017-04-12" version="1">MKFSATLATVTLVALAACSAPTPGPAEGSAPPTESTELTVVTHDSFTLPDELKEQFAEETGYEVTYLAPGDAGALVNQLILTKDSPLGDVVYGIDNTFASRADDEGILTDYDSPALPQSSTQFDAAGLTPIDFGDVCINADKDWFEERDLPLPTTLDDLTDPRYKDLLVVTNPASSSPGLAFLIATIGAKGDGYLDYWRSLMDNGTLVTSGWSDAYYTEFSGADGEGPRPLVLSYATSPAFTVEDGESSTVALLGTCFRQIEYAGVLAGAENEAGARAFIDFMLSPKVQRAIPTNLYMYPVVADTPLPEEWVKFAPLPTQPIEVSADRISENRDQWIRDWTEATSDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC75</accession>
    <name>A0A1Q2CC75_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Polyphosphate kinase 2</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Polyphosphate kinase 2, PA0141 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_01820</name>
        <name evidence="5" type="ORF">SAMN05428934_108112</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ03092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01820"/>
    <dbReference type="EnsemblBacteria" id="AQP43701">
        <property type="protein sequence ID" value="AQP43701"/>
        <property type="gene ID" value="RPIT_01820"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ03092">
        <property type="protein sequence ID" value="SDZ03092"/>
        <property type="gene ID" value="SAMN05428934_108112"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01820"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022488">
        <property type="entry name" value="PPK2-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022486">
        <property type="entry name" value="PPK2_PA0141"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03976">
        <property type="entry name" value="PPK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03707">
        <property type="entry name" value="PPK2_P_aer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPK2" evidence="3">
        <location>
            <begin position="51"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ03092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="304" mass="35449" checksum="24D73028633572DC" modified="2017-04-12" version="1">MSQSLREYIDMLRAEGYAVADVHGEDPYLIDPLGNAVETWQEKYPYDELISRSEYETEKRQLQIELLKLQYSAQDRGTKHVIIFEGRDAAGKGGAIKRFTEHLNPRNARVVALAAPTERERGQWYFQRYIQHLPTAGEIVLFDRSWYNRAGVERVMGFCTDEEYEIFVRQAPIFEEMLIESGITVTKLWFSVTQREQRTRFAIRQIDPVRQWKLSPMDLESLGRWDDYTAAKTAMLRHTDTAVAPWYRIKSNDKKRARLNAMRLFLDLHDYDGKDASVIKPTDPLIVTRGYKNRSAAQLDESDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCA6</accession>
    <name>A0A1Q2CCA6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01910</name>
        <name evidence="3" type="ORF">RPIT_02020</name>
        <name evidence="4" type="ORF">RPIT_07220</name>
        <name evidence="5" type="ORF">SAMN05428934_1341</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000034">
        <property type="protein sequence ID" value="SDZ24690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43716">
        <property type="protein sequence ID" value="AQP43716"/>
        <property type="gene ID" value="RPIT_01910"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43736">
        <property type="protein sequence ID" value="AQP43736"/>
        <property type="gene ID" value="RPIT_02020"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44628">
        <property type="protein sequence ID" value="AQP44628"/>
        <property type="gene ID" value="RPIT_07220"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ24690">
        <property type="protein sequence ID" value="SDZ24690"/>
        <property type="gene ID" value="SAMN05428934_1341"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01910"/>
    <dbReference type="KEGG" id="tfl:RPIT_02020"/>
    <dbReference type="KEGG" id="tfl:RPIT_07220"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="1">
        <location>
            <begin position="20"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ24690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="363" mass="39412" checksum="91FE4D579FA8717E" modified="2017-04-12" version="1">MYKTSHTRRHRNPPSGSVVVGIDTHLDIHHAALVDAATGAPVADQQFPATPAGYLELLDWAVGHGRVSRAGVEQTGTYGAGLSAVLHAAGIEVIEINHTERGDRARHGKTDELDAYRAATAAAAGTQKGLAKHYHPAIAALRPLMVLRAHHRSSRQRAWGRVGGMLVTCPDDLADQVRGLNSAQKLARIAAWRPDLTRLHDPVNSYKLALRDLARACLDHDRAIVEIDAQLLRILTPIAPTLLAQHHVGPVTTAQLLITAGHPGRITSGDAFAKLVGVAPLPVQSGKSSRWRLSRSGDRQANSVIHRVVIGRLGTDPRSKTYIQRRVSEGKTRSEAIRALKRHVTRDLWTALQTDLNNLPHTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCB8</accession>
    <name>A0A1Q2CCB8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Molybdenum cofactor biosynthesis protein MoaE</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Molybdopterin synthase subunit MoaE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_02160</name>
        <name evidence="2" type="ORF">SAMN05428934_10130</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY23200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02160"/>
    <dbReference type="EnsemblBacteria" id="AQP43763">
        <property type="protein sequence ID" value="AQP43763"/>
        <property type="gene ID" value="RPIT_02160"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY23200">
        <property type="protein sequence ID" value="SDY23200"/>
        <property type="gene ID" value="SAMN05428934_10130"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02160"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00756">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036563">
        <property type="entry name" value="MoaE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003448">
        <property type="entry name" value="Mopterin_biosynth_MoaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02391">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54690">
        <property type="entry name" value="SSF54690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY23200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="137" mass="14556" checksum="9012C6F3ADE5F20E" modified="2017-04-12" version="1">MELTRVTTADIDTDALLASVSDDRAGAVVSFAGVVRNHDHGKTVTGIEYVGHPTADEVLREVVAEFSGRDGVHAIVAQHRVGMLGIGGVALYVAVAASHRAQAFDCASGLVDRVKEVLPIWKKQLLADGTHEWSQCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCD6</accession>
    <name>A0A1Q2CCD6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_02240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43778">
        <property type="protein sequence ID" value="AQP43778"/>
        <property type="gene ID" value="RPIT_02240"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02240"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="149" mass="16361" checksum="D0D67E9DAE50CE6A" modified="2017-04-12" version="1">MRGSGWTSSCLDVRGWDLVWCDEDVYRRYRVKKATRSEETGEFEMLMGANSNLLKPAIDADSLIREEQWVLGYTVTPLRTIDEVFVAEILGSTASRVGHLLLGPHVSLGPTSSRDGGRFLSDAEDQLPGFDDDSLVGRGMLPGLLGVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCE7</accession>
    <name>A0A1Q2CCE7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Abortive infection C-terminus</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_02230</name>
        <name evidence="4" type="ORF">SAMN05428934_10145</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY23663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43776">
        <property type="protein sequence ID" value="AQP43776"/>
        <property type="gene ID" value="RPIT_02230"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY23663">
        <property type="protein sequence ID" value="SDY23663"/>
        <property type="gene ID" value="SAMN05428934_10145"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02230"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026001">
        <property type="entry name" value="Abi-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14355">
        <property type="entry name" value="Abi_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abi_C" evidence="2">
        <location>
            <begin position="192"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY23663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="275" mass="29372" checksum="90BDE4E3BB2CE4A5" modified="2017-04-12" version="1">MSLIEIGSVLGSFFERGQGPSHDELDRAVERSHLQAGDPAPSGRSPEGSAIGKTKRIRQIMTYAADHDPAAGLQLCRHLVDLMRADGMFTTTLDNHAGSDKITRLQEALSRAGYTLTSGGILHPTVIDNLTGTELTDVLRAYVNRVNLNPDDAPLQIGTGKELDEAAARHVLQDRHGHYPVGGHAGSYPVTLAAAFTALGLEIAPDLTTQLHPNPHKQVQQCLFLLGVAVNRLRNDAGTGHGRPDEPRRSGRLSAAEGRLVARATALLAGMLLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCE9</accession>
    <name>A0A1Q2CCE9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Nitrate reductase gamma subunit</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="16">Respiratory nitrate reductase subunit gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">RPIT_02145</name>
        <name evidence="17" type="ORF">SAMN05428934_10127</name>
    </gene>
    <organism evidence="16 18">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 18" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1T</strain>
        </source>
    </reference>
    <reference evidence="17 19" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">RP1</strain>
        </source>
    </reference>
    <reference evidence="16" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY23105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02145"/>
    <dbReference type="EnsemblBacteria" id="AQP43760">
        <property type="protein sequence ID" value="AQP43760"/>
        <property type="gene ID" value="RPIT_02145"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY23105">
        <property type="protein sequence ID" value="SDY23105"/>
        <property type="gene ID" value="SAMN05428934_10127"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02145"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009325">
        <property type="term" value="C:nitrate reductase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008940">
        <property type="term" value="F:nitrate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023234">
        <property type="entry name" value="NarG-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036197">
        <property type="entry name" value="NarG-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003816">
        <property type="entry name" value="Nitrate_red_gam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02665">
        <property type="entry name" value="Nitrate_red_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103501">
        <property type="entry name" value="SSF103501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00351">
        <property type="entry name" value="narI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
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</entry>
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            <authorList>
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                <person name="Schumann P."/>
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    <sequence length="640" mass="65291" checksum="6A5BA4D03EEA55B5" modified="2017-04-12" version="1"> </sequence>
</entry>
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    </dbReference>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY26892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02775"/>
    <dbReference type="EnsemblBacteria" id="AQP43871">
        <property type="protein sequence ID" value="AQP43871"/>
        <property type="gene ID" value="RPIT_02775"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY26892">
        <property type="protein sequence ID" value="SDY26892"/>
        <property type="gene ID" value="SAMN05428934_101155"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02775"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="232"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY26892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="250" mass="25993" checksum="F11D6359FACC5E5A" modified="2017-04-12" version="1">MELEIIVAVGLLIGLSAILYSSVGHGGGSGYLAVMALFSVTTEVMRPTALVLNIAVAAIGFAAFYRRGAFSWRVLWPFAVTAVPMAFVGGLIHVPGVVYKPLLAAVLIYSAGYLFWPKADPADDPGMRPPVLPALAIGAFVGLLSGVTGIGGGIFLSPILLFRRWADTKTTAGVAAAFILLNSASGLAGQLQLLDSIPLDAIAVWVPLAVLGGFLGSRYGSRTPRNIHIQRLLGVVLLVAAGKMLLTIGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCV2</accession>
    <name>A0A1Q2CCV2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate ABC transporter substrate-binding protein, CUT1 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Sugar ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03260</name>
        <name evidence="3" type="ORF">SAMN05428934_101253</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03260"/>
    <dbReference type="EnsemblBacteria" id="AQP43953">
        <property type="protein sequence ID" value="AQP43953"/>
        <property type="gene ID" value="RPIT_03260"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29901">
        <property type="protein sequence ID" value="SDY29901"/>
        <property type="gene ID" value="SAMN05428934_101253"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03260"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544432" evidence="1">
        <location>
            <begin position="39"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY29901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="459" mass="48464" checksum="D384DC94E3E24A59" modified="2017-04-12" version="1">MTLRPIHRRHFLLGASGLASAAVLAACAPGETAPTTTAAPGDTTAAAPEATDPAELGDVELVVWDQEVRGSQNDALVALIAAFEEKYPNITINRTSQSFDDLKAQVSLALSGNDVPDVVQVNNARGDMGQFVKAGQLLDLSPYAAQYGWEDRFPASVLGKVRYSSDATTFGEGNLYGLPQTGEIVGIFYSQKKLDALGASAPETWEDYFAILDAAKAAGEQPMVLGNIEKWPALHVFGPLQAHYVEPEDVVKLGMGNEGASWTSEGNTAAMEQFAKWGLEGYFGTSPNGLDYDPAWTEFTQGTGVFLPGGSWLGTDMEAVMGEDLKFMAPPPATNGELATTGGTGIPFSIPAKAKNAAAAAAYIDFITSDEAMEIIAENGGMPVLRTAELAPEAGVQKDIYEAFDTVSQEGTLLPYLDYATPSFSDTAGTGLQEVLGGQKTPEEVLADFEADYQAFIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCV4</accession>
    <name>A0A1Q2CCV4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glyoxylase, beta-lactamase superfamily II</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">MBL fold metallo-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_03105</name>
        <name evidence="4" type="ORF">SAMN05428934_101222</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY28935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03105"/>
    <dbReference type="EnsemblBacteria" id="AQP43927">
        <property type="protein sequence ID" value="AQP43927"/>
        <property type="gene ID" value="RPIT_03105"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY28935">
        <property type="protein sequence ID" value="SDY28935"/>
        <property type="gene ID" value="SAMN05428934_101222"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03105"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050313">
        <property type="term" value="F:sulfur dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07724">
        <property type="entry name" value="POD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044528">
        <property type="entry name" value="POD-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="259"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="362"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY28935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="448" mass="48602" checksum="BCA4CA3077C8D936" modified="2017-04-12" version="1">MPTIHTIETKSLGDRSYLVHDGDVAFVIDPQRDIERVLKLATDEGVRIEAIFETHIHNDYVTGGYALAQQVGAKYYVNGDDDVSFERTPIADKDVIDVGSMKVQALLTPGHTFTHLSYALLDDAEPVVFTGGSLLYGATGRPDLLGKEHAEALARHQHASAHRLASELPDETQIMPTHGFGSFCSATPTTGDSSTIGLEKKQNPALTQGEEEYVEALLAGLDVFPAYYAHMGPANASGPDASDLSPVHRADKQELRARLEAGEWLVDLRTRTAFAAGHAPGTYNIGLDGQFSTYLGWLIPWGTPVTLLGESEEQVAEAQREMTLIGIDRAAASATGGPSDWTDDELGTLTRATFADLAQVKHHREVVILDTRRKQEWDESHIEGAVHIPLHDILKRMDEVPDGELWVHCAGGYRASIASSILQAAGKTVVHVDDSFDEQARAAGLTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCX1</accession>
    <name>A0A1Q2CCX1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03205</name>
        <name evidence="3" type="ORF">SAMN05428934_101242</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43946">
        <property type="protein sequence ID" value="AQP43946"/>
        <property type="gene ID" value="RPIT_03205"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29581">
        <property type="protein sequence ID" value="SDY29581"/>
        <property type="gene ID" value="SAMN05428934_101242"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03205"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="DUF1707"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08044">
        <property type="entry name" value="DUF1707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY29581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="120" mass="12618" checksum="514F77EA981E83FA" modified="2017-04-12" version="1">MALPPSSKYLQRANDPVDEVERDSLNRRLNAAFADGRITHDDYAAAMDTVYGARVLGDLVPVIERLPAAAVDVPAIVQQGGPPAGRVAESRNLVPVAIGVGLVGISLLTILLLILAVVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCZ9</accession>
    <name>A0A1Q2CCZ9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_03095</name>
        <name evidence="4" type="ORF">SAMN05428934_101220</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY28877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03095"/>
    <dbReference type="EnsemblBacteria" id="AQP43925">
        <property type="protein sequence ID" value="AQP43925"/>
        <property type="gene ID" value="RPIT_03095"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY28877">
        <property type="protein sequence ID" value="SDY28877"/>
        <property type="gene ID" value="SAMN05428934_101220"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544419" evidence="2">
        <location>
            <begin position="27"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="543"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="564"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY28877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="604" mass="63052" checksum="17A91C2F8454022E" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD04</accession>
    <name>A0A1Q2CD04_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">D-xylose ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Monosaccharide ABC transporter ATP-binding protein, CUT2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_03295</name>
        <name evidence="6" type="ORF">SAMN05428934_101260</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03295"/>
    <dbReference type="EnsemblBacteria" id="AQP43960">
        <property type="protein sequence ID" value="AQP43960"/>
        <property type="gene ID" value="RPIT_03295"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30118">
        <property type="protein sequence ID" value="SDY30118"/>
        <property type="gene ID" value="SAMN05428934_101260"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03295"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="252"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
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            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY30118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="500" mass="55329" checksum="CF85361091E79390" modified="2017-04-12" version="1">MQEVILRMRDIRKTFPGVVALDGVQLDVRSGTVHSLMGENGAGKSTLMKCLIGMYTPDAGTIELAGDQMQFKDTKDGLEHGISMIHQELSPVPEMMVAENIWLGREQRGKFGLLDPKLIIRKTQELFDEWDIKIDPRAKMKNLTVARQQMVEIAKAISYDAKIIIMDEPTSAIPEREVDHLHRMIKRLTDYGVAIIYITHKMDEVFKISDDITVFRDGKHVASLPAKELNRDKLIQLMVGRELTSLFPKLDAEIGDVALSVRNLNRGKLVRDVSFDVRAGEILGFAGLMGAGRTEVLETIFGIHPAESGEILVHGNPVKIREPKDAIAANIGMLTEDRKHNGIMGVLSVRDNITIAALPQFSPKGFLKISELNRVSEEQRQALRIKTPTLNQLIKNLSGGNQQKALISRWLLTVPDVLMIDEPTRGIDVGAKSEIHRLMSQLAQQGKAVIMVSSELPEVLGMSDRVIVMHEGRISGELSRAEANQESIMHLATGGDAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD91</accession>
    <name>A0A1Q2CD91_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Response regulator receiver and ANTAR domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_04090</name>
        <name evidence="5" type="ORF">SAMN05428934_101421</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY34699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04090"/>
    <dbReference type="EnsemblBacteria" id="AQP44093">
        <property type="protein sequence ID" value="AQP44093"/>
        <property type="gene ID" value="RPIT_04090"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY34699">
        <property type="protein sequence ID" value="SDY34699"/>
        <property type="gene ID" value="SAMN05428934_101421"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04090"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005561">
        <property type="entry name" value="ANTAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008327">
        <property type="entry name" value="Sig_transdc_resp-reg_antiterm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03861">
        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036382">
        <property type="entry name" value="RR_antiterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01012">
        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50921">
        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="6"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="ANTAR" evidence="3">
        <location>
            <begin position="126"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY34699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="192" mass="21394" checksum="99FF5DF682131793" modified="2017-04-12" version="1">MKKKPTVIVAEDEALIRLDLVELLTEEGYEVVGEAADGEEAVKLARELEPNLVIMDVKMPKMDGITAAEIIAEERIAPIVMLTAFSQRELVERARDAGAMAYVVKPFGASDVIPAIEIAMGRFQEIKAIEDELNSLEDRLESRKIIDQAKGILQADLGFTEPEAFRWIQKTAMDLRKSMRDVAEGVISHKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD99</accession>
    <name>A0A1Q2CD99_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_03940</name>
        <name evidence="2" type="ORF">SAMN05428934_101392</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY33864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03940"/>
    <dbReference type="EnsemblBacteria" id="AQP44071">
        <property type="protein sequence ID" value="AQP44071"/>
        <property type="gene ID" value="RPIT_03940"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY33864">
        <property type="protein sequence ID" value="SDY33864"/>
        <property type="gene ID" value="SAMN05428934_101392"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03940"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045443">
        <property type="entry name" value="DUF6504"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20114">
        <property type="entry name" value="DUF6504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY33864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="100" mass="11785" checksum="215FF4DF2944EF2E" modified="2017-04-12" version="1">MRAYDEPIHVLFREEPRQFIWRDRLLLVKEVQGRWSRAMPWWLGQQARAARGEEVASTQGDLVREREVWRVEAGNGAHRGVYELARTVDAEDWVLQAVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDC1</accession>
    <name>A0A1Q2CDC1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">6-phosphogluconolactonase</fullName>
            <shortName evidence="7">6PGL</shortName>
            <ecNumber evidence="5 7">3.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pgl</name>
        <name evidence="9" type="ORF">RPIT_04260</name>
        <name evidence="10" type="ORF">SAMN05428934_101456</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12556"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="3.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.31" evidence="5 7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY35795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04260"/>
    <dbReference type="EnsemblBacteria" id="AQP44123">
        <property type="protein sequence ID" value="AQP44123"/>
        <property type="gene ID" value="RPIT_04260"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY35795">
        <property type="protein sequence ID" value="SDY35795"/>
        <property type="gene ID" value="SAMN05428934_101456"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04260"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00409"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01400">
        <property type="entry name" value="6PGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005900">
        <property type="entry name" value="6-phosphogluconolactonase_DevB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039104">
        <property type="entry name" value="PGLS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054">
        <property type="entry name" value="PTHR11054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01198">
        <property type="entry name" value="pgl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine_iso" evidence="8">
        <location>
            <begin position="10"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY35795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="243" mass="26490" checksum="9C00B6BF74D827E0" modified="2017-04-12" version="1">MHTRVVRLSDAAEVSEAVAAQLLKRVLQLQQRQPVVHLCLTGGNAANDMYERFAELAEHSELDSTRLQLWWGDERFVPATDPDRNSQQAVTRLARTISIRSADTHMMAAQDGRKDSHEAAAEYESELGETHFDLTLLGIGPDGHVASIFPNHPSFDPTNRKVIGVEDSPKPPAERISLTIPALNNSAEIWVMATGDVKANAVARTLDGDLSLPAAHIQAEGATVWFLDEAAAADLPPQHSCSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDD2</accession>
    <name>A0A1Q2CDD2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable cell division protein WhiA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">whiA</name>
        <name evidence="9" type="ORF">RPIT_04205</name>
        <name evidence="10" type="ORF">SAMN05428934_101445</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in cell division and chromosome segregation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WhiA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY35486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04205"/>
    <dbReference type="EnsemblBacteria" id="AQP44114">
        <property type="protein sequence ID" value="AQP44114"/>
        <property type="gene ID" value="RPIT_04205"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY35486">
        <property type="protein sequence ID" value="SDY35486"/>
        <property type="gene ID" value="SAMN05428934_101445"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04205"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043937">
        <property type="term" value="P:regulation of sporulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01420">
        <property type="entry name" value="HTH_type_WhiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027434">
        <property type="entry name" value="Homing_endonucl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018478">
        <property type="entry name" value="Sporu_reg_WhiA_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003802">
        <property type="entry name" value="Sporulation_regulator_WhiA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023054">
        <property type="entry name" value="Sporulation_regulator_WhiA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039518">
        <property type="entry name" value="WhiA_LAGLIDADG_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37307">
        <property type="entry name" value="PTHR37307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02650">
        <property type="entry name" value="HTH_WhiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14527">
        <property type="entry name" value="LAGLIDADG_WhiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10298">
        <property type="entry name" value="WhiA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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            <end position="103"/>
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            <end position="218"/>
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            <dbReference type="Pfam" id="PF02650"/>
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    </evidence>
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            <dbReference type="Pfam" id="PF10298"/>
        </source>
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            <dbReference type="Pfam" id="PF14527"/>
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        <source>
            <dbReference type="EMBL" id="AQP44114.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY35486.1"/>
        </source>
    </evidence>
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            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="327" mass="35460" checksum="299024F4367CD8DB" modified="2017-04-12" version="1">MALTQKVKSELATVVAPHPSVRRAEVAAMLRFAGGLHLVGGRIVIEAELDTGAAARRLRTFIADLYSVDSELMVINGSGVRRGPRYTLRVVRDGEQLARLSGLVDQNRRPVRGLPPAVVAGSPADAVAVWRGAFLARGSLTEPGRSMALEVTCPGSEAALALVGAARRLGISVKSREVRGVERVLIRDGDSIAELLTQMGAAETRITWEERRKRREVRANVNRLANFDDANLRRSARAAVTASARVERAMEILGDQVPEHLRAAGELRLEHRQASLEELGKLHEPPLTKDAIAGRIRRLLATADKMADDEGVPNTEASLPPDLRDVD</sequence>
</entry>
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    </protein>
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 7">RP1</strain>
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    </reference>
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        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
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        </source>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="SAMN05428934_101397"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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            <end position="27"/>
        </location>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="725" mass="76084" checksum="56E4246AAA272FC0" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 5" key="2">
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            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP44136">
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    </dbReference>
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        <property type="gene ID" value="SAMN05428934_101472"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        </source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="223" mass="24503" checksum="CBEB9992DBDBCA63" modified="2017-04-12" version="1">METTHLEVPTRRRVVNLVLNEGPQTAKQLAERLDLTPAAVRRHLSSLLEDGTLESREQRIYGHRGRGRPSKVFALTDAGRAEFRQGYDQLALAALRRLVEAAGPESVEEIAHDQLADIERRFHAERDACPEAPAISVLAAVLSADGFAASIRPLPSGDQLLQHHCPIAHVASEFPVICEVETRLIAHLLGSHVQRLATIAHGDGVCTTHIPRPLPTPLIPRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDG4</accession>
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    </gene>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP44162.1"/>
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    </dbReference>
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        <property type="protein sequence ID" value="SDY37003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04490"/>
    <dbReference type="EnsemblBacteria" id="AQP44162">
        <property type="protein sequence ID" value="AQP44162"/>
        <property type="gene ID" value="RPIT_04490"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37003">
        <property type="protein sequence ID" value="SDY37003"/>
        <property type="gene ID" value="SAMN05428934_101504"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04490"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
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        <property type="entry name" value="Peptidase_M23"/>
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        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544442" evidence="1">
        <location>
            <begin position="22"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="47"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="196"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY37003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="292" mass="29742" checksum="91B4A096E1CCF4AC" modified="2017-04-12" version="1">MRLLLPMVVVLLLAIPAPAGAAGFELVAPIPGPAVRGYDDVGRFAAGHRGVDLGGSTGDPVRAAAAGRVLFAGNVAGRGTVSVDHGNGWRTTYQPVLATVGAGDVVEAGDAIGSLLAGHCAGACLHWGLTDGETYANPLAFLRLPPVRLVPAGSAPPPLPRIAAATVGALDGLPLRGRLTSRFGPRLHPVLGVFRLHDGVDLAAPCGTPVVVPNGGTVTRVDHHPAYGRRVVVDHGGGRATGYTHLQQAHVRRGQVVAGGDRIGTVGSSGLSTGCHLHWMAWRDGAVVDPMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDG5</accession>
    <name>A0A1Q2CDG5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">DNA polymerase I</fullName>
            <ecNumber evidence="2 11">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">polA</name>
        <name evidence="15" type="ORF">RPIT_04100</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the DNA polymerase type-A family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2 11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04100"/>
    <dbReference type="EnsemblBacteria" id="AQP44095">
        <property type="protein sequence ID" value="AQP44095"/>
        <property type="gene ID" value="RPIT_04100"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04100"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09898">
        <property type="entry name" value="H3TH_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020046">
        <property type="entry name" value="5-3_exonucl_a-hlix_arch_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020045">
        <property type="entry name" value="DNA_polI_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018320">
        <property type="entry name" value="DNA_polymerase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002298">
        <property type="entry name" value="DNA_polymerase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10133">
        <property type="entry name" value="PTHR10133"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01367">
        <property type="entry name" value="5_3_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02739">
        <property type="entry name" value="5_3_exonuc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00868">
        <property type="entry name" value="DNAPOLI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00475">
        <property type="entry name" value="53EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="SSF47807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00593">
        <property type="entry name" value="pola"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 11" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="53EXOc" evidence="13">
        <location>
            <begin position="5"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="3'-5' exonuclease" evidence="12">
        <location>
            <begin position="309"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="POLAc" evidence="14">
        <location>
            <begin position="647"/>
            <end position="854"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="AQP44095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="891" mass="97761" checksum="D1EA42A14BBE8819" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDI2</accession>
    <name>A0A1Q2CDI2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_04525</name>
        <name evidence="10" type="ORF">SAMN05428934_101511</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 7">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04525"/>
    <dbReference type="EnsemblBacteria" id="AQP44169">
        <property type="protein sequence ID" value="AQP44169"/>
        <property type="gene ID" value="RPIT_04525"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37171">
        <property type="protein sequence ID" value="SDY37171"/>
        <property type="gene ID" value="SAMN05428934_101511"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04525"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004353">
        <property type="term" value="F:glutamate dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05313">
        <property type="entry name" value="NAD_bind_2_Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014362">
        <property type="entry name" value="Glu_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033922">
        <property type="entry name" value="NAD_bind_Glu_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000185">
        <property type="entry name" value="Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="8">
        <location>
            <begin position="203"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="6">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY37171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="445" mass="48513" checksum="3C999CCCA1486A60" modified="2017-04-12" version="1">MDQKLEGVYDAVVARNPGEAEFHQAVREVLESLGPVIDRHPEYLEMKMLERICEPERQIIFRVPWMDDKGEVHINRGFRVEFNSALGPYKGGLRFHPSVYLGVIKFLGFEQIFKNSLTGLPIGGGKGGSDFDPRGKSDSEVMRFCQSFMTELYRHLGEYTDVPAGDIGVGGREIGYMFGQYKRITNRYESGVLTGKGIAWGGSLVRTEATGYGTVVFANEMLKTRGESIDGKKVMVSGSGNVAIYAMEKVRQLGGLPIGFSDSSGYVVDEAGVDLDLLKQIKEIERGRVSDYAERRESASFSDRGSIWDVPVDVALPCATQNELNGEQAATLVKNGVKAVAEGANMPTTPEGIHVFQQAGVLYGPGKAANAGGVATSALEMQQNASRDSWTFEYTEERLTDIMVNIHDQVATTAESYGAPGDYVMGANIHGFEKVANAIQAFGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDJ0</accession>
    <name>A0A1Q2CDJ0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_04580</name>
        <name evidence="7" type="ORF">SAMN05428934_101522</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transglycosylase family. Rpf subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04580"/>
    <dbReference type="EnsemblBacteria" id="AQP44179">
        <property type="protein sequence ID" value="AQP44179"/>
        <property type="gene ID" value="RPIT_04580"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37435">
        <property type="protein sequence ID" value="SDY37435"/>
        <property type="gene ID" value="SAMN05428934_101522"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04580"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13925">
        <property type="entry name" value="RPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007137">
        <property type="entry name" value="DUF348"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011098">
        <property type="entry name" value="G5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010618">
        <property type="entry name" value="RPF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03990">
        <property type="entry name" value="DUF348"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07501">
        <property type="entry name" value="G5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06737">
        <property type="entry name" value="Transglycosylas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01208">
        <property type="entry name" value="G5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51109">
        <property type="entry name" value="G5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544439" evidence="4">
        <location>
            <begin position="28"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="G5" evidence="5">
        <location>
            <begin position="197"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="263"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY37435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="390" mass="40855" checksum="E26DFA724A455C66" modified="2017-04-12" version="1">MARSYLIPVLAGVSALALVGGATAVSALEKNDVTLVVDGTAKTVALREDTVAEVLELEGIELGSHDVVLPAADSEIVDGIEISVAYGRPLDVTVDGESRRVWTTARSVGEALRMLDLDASTSLVSASRSQSIGRAGLEVDIQTAKDVQLIAAGSTTSITLAGTVQDVLDKAGVAPDADDKVSPAPTTALADGMTIQVVAVEVKQSTKTVELPYEKTSVKTDKLYTGEQKVTTKGVVGVKTETYTDIYEDGVLVSSELAGSEVTKQPVAQVTSIGTKAKPKPKPAPAPAPQKTESKSSSSSSTPAASTSSSGLNLAREAMWVRIAECESNNRWNINTGNGYYGGLQFNLPTWRSVGGTDFAPYPHQASRAEQITVANRLYAQRGTQPWSCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDM5</accession>
    <name>A0A1Q2CDM5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_04810</name>
        <name evidence="4" type="ORF">SAMN05428934_101570</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY38630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44218">
        <property type="protein sequence ID" value="AQP44218"/>
        <property type="gene ID" value="RPIT_04810"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY38630">
        <property type="protein sequence ID" value="SDY38630"/>
        <property type="gene ID" value="SAMN05428934_101570"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04810"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY38630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="214" mass="23550" checksum="9FDBA02497E1E5F4" modified="2017-04-12" version="1">MSNQQWPPPGSQQNNPWAQQDPNWRPQQFHDAQGRDPRQPFGQSDHRQPSIEELTPPRKSKGVWGIVIGVVVLIATLLVGAQFFTGGPAEPAAPVSASADAQATPTESRTGNYIPFEGNGDGIFEIVDYQWGEQKLRLRIRVEIETGEYGFAVFAFTNESRDSYDPVDPSSFIVRAGEPVEREVTFYMPQADSTIVLTTPSGRVALNALPVEAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDM8</accession>
    <name>A0A1Q2CDM8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxygen-dependent protoporphyrinogen oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04725</name>
        <name evidence="3" type="ORF">SAMN05428934_101554</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY38221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04725"/>
    <dbReference type="EnsemblBacteria" id="AQP44206">
        <property type="protein sequence ID" value="AQP44206"/>
        <property type="gene ID" value="RPIT_04725"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY38221">
        <property type="protein sequence ID" value="SDY38221"/>
        <property type="gene ID" value="SAMN05428934_101554"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04725"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY38221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="427" mass="43950" checksum="CE1201B75C8A005B" modified="2017-04-12" version="1">MTAIVVGGGLAGLVAGYRLAKAGRRVTVMEATTRLGGMIHPVEVGGVRVDAGAEAYAIRGGAARALCEELGLELAAPAGQPHLWWPRGTWPMAEGVLGIPASLDDPALGALDPDELETLTRDGELPASVGADASTVGELVRARLGDGAVRRLVAPVAHGVYALDPDRMPLNAFAPGLLAALAEHGSLLAAVASMRHPGRAAVEQPVGGMYTLIDTLAERIVDLGGEVRTASPIVAVAHAGPDFVVGLPGGEKLRADRLVLATPGAAAVSLLGRLAVDVAAPPIKKARQAVLAVEHPGLADGPVGSGLLVGESDPSIGAKALTHYSLKWPWARRGDQEIFRLSYPENHVPSRTDVMADASRFLGVELRDAQITGFAAVTWDAMPGRLDAPVREFVLDTVAKAGIDVVGAWLDGNGITAVVAGCDRVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDP6</accession>
    <name>A0A1Q2CDP6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Leucine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Leucyl-tRNA synthetase</fullName>
            <shortName evidence="9">LeuRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">leuS</name>
        <name evidence="15" type="ORF">RPIT_04825</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04825"/>
    <dbReference type="EnsemblBacteria" id="AQP44221">
        <property type="protein sequence ID" value="AQP44221"/>
        <property type="gene ID" value="RPIT_04825"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04825"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00049_B">
        <property type="entry name" value="Leu_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025709">
        <property type="entry name" value="Leu_tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="PTHR43740"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13603">
        <property type="entry name" value="tRNA-synt_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00985">
        <property type="entry name" value="TRNASYNTHLEU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00396">
        <property type="entry name" value="leuS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1g" evidence="13">
        <location>
            <begin position="45"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1_2" evidence="14">
        <location>
            <begin position="227"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1" evidence="11">
        <location>
            <begin position="425"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="12">
        <location>
            <begin position="663"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="9">
        <location>
            <begin position="588"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="591"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="AQP44221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="823" mass="91961" checksum="5A3DE91FD714DC57" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDR6</accession>
    <name>A0A1Q2CDR6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Queuine tRNA-ribosyltransferase</fullName>
            <ecNumber evidence="4">2.4.2.29</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Guanine insertion enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-guanine transglycosylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">tgt</name>
        <name evidence="6" type="ORF">RPIT_04980</name>
        <name evidence="7" type="ORF">SAMN05428934_101602</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>7-aminomethyl-7-carbaguanine + guanosine(34) in tRNA = 7-aminomethyl-7-carbaguanosine(34) in tRNA + guanine</text>
            <dbReference type="Rhea" id="RHEA:24104"/>
            <dbReference type="Rhea" id="RHEA-COMP:10341"/>
            <dbReference type="Rhea" id="RHEA-COMP:10342"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:58703"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:82833"/>
            <dbReference type="EC" id="2.4.2.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the queuine tRNA-ribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.29" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY39445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04980"/>
    <dbReference type="EnsemblBacteria" id="AQP44246">
        <property type="protein sequence ID" value="AQP44246"/>
        <property type="gene ID" value="RPIT_04980"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY39445">
        <property type="protein sequence ID" value="SDY39445"/>
        <property type="gene ID" value="SAMN05428934_101602"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04980"/>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008479">
        <property type="term" value="F:queuine tRNA-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101030">
        <property type="term" value="P:tRNA-guanine transglycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00168">
        <property type="entry name" value="Q_tRNA_Tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004803">
        <property type="entry name" value="TGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="SSF51713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00430">
        <property type="entry name" value="Q_tRNA_tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TGT" evidence="5">
        <location>
            <begin position="18"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="95"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="303"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="372"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY39445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="408" mass="45357" checksum="2E4A19DEF86E80A4" modified="2017-04-12" version="1">MTAAFSFDVTHRLDGAPGRAGVIHTPHGRIETPAFIVVGTKATVKAVLPEAVAELGGQAVLANAYHLYLQPGADLVDEAGGLGAFMNWPGPTFTDSGGFQVMSLGAGFKKVLAMDTAGLQDDDVIAEGKTRMAHVDDDGVTFKSHLDGTRHRFTPEVSMRIQHQLGADVMFAFDELTTLMNTRGYQEQSVERTHRWAERCLAEHRRLTDERAGKPYQALFGVIQGAQYEDLRRRAARGLAELEVDGQSFDGFGLGGALEKENLGEIIGWMVEELPESKPRHLLGISEPDDFFAAIEMGADTFDCVNPSRVARNAAIYTADGRYNVNTARHKRSFIPLEEGCDCYTCTHYTRAYIHHLFKAKEMLSSTLATIHNERFTVRLVDNIRAALREGRFYEYRDEFLGRFYART</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDS7</accession>
    <name>A0A1Q2CDS7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13">DNA primase</fullName>
            <ecNumber evidence="12">2.7.7.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">dnaG</name>
        <name evidence="17" type="ORF">RPIT_05105</name>
        <name evidence="18" type="ORF">SAMN05428934_101627</name>
    </gene>
    <organism evidence="17 19">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 19" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">RP1T</strain>
        </source>
    </reference>
    <reference evidence="18 20" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">RP1</strain>
        </source>
    </reference>
    <reference evidence="17" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12 13 14">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12 13 14">Binds 1 zinc ion per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer. Interacts with DnaB.</text>
    </comment>
    <comment type="domain">
        <text evidence="12">Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12 13">Belongs to the DnaG primase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.101" evidence="12"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY40114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05105"/>
    <dbReference type="EnsemblBacteria" id="AQP44269">
        <property type="protein sequence ID" value="AQP44269"/>
        <property type="gene ID" value="RPIT_05105"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY40114">
        <property type="protein sequence ID" value="SDY40114"/>
        <property type="gene ID" value="SAMN05428934_101627"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05105"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003896">
        <property type="term" value="F:DNA primase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03364">
        <property type="entry name" value="TOPRIM_DnaG_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00974">
        <property type="entry name" value="DNA_primase_DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013264">
        <property type="entry name" value="DNA_primase_core_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037068">
        <property type="entry name" value="DNA_primase_core_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019475">
        <property type="entry name" value="DNA_primase_DnaB-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006295">
        <property type="entry name" value="DNA_primase_DnaG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013173">
        <property type="entry name" value="DNA_primase_DnaG_DnaB-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030846">
        <property type="entry name" value="DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034151">
        <property type="entry name" value="TOPRIM_DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002694">
        <property type="entry name" value="Znf_CHC2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10410">
        <property type="entry name" value="DnaB_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08278">
        <property type="entry name" value="DnaG_DnaB_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13662">
        <property type="entry name" value="Toprim_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08275">
        <property type="entry name" value="Toprim_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01807">
        <property type="entry name" value="zf-CHC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002811">
        <property type="entry name" value="DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00766">
        <property type="entry name" value="DnaG_DnaB_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00400">
        <property type="entry name" value="ZnF_CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01391">
        <property type="entry name" value="dnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 12 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 12 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2 12 13" id="KW-0639">Primosome</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 12 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 12 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 12 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 12 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="16">
        <location>
            <begin position="258"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CHC2-type" evidence="12 14">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="432"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="432"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR002811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR002811-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="AQP44269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="SDY40114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="610" mass="67529" checksum="01B75D0DE4A9EFFC" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDS8</accession>
    <name>A0A1Q2CDS8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">3-oxoacyl-[acyl-carrier-protein] synthase II</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Beta-ketoacyl-[acyl-carrier-protein] synthase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_05195</name>
        <name evidence="5" type="ORF">SAMN05428934_101645</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY40568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05195"/>
    <dbReference type="EnsemblBacteria" id="AQP44282">
        <property type="protein sequence ID" value="AQP44282"/>
        <property type="gene ID" value="RPIT_05195"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY40568">
        <property type="protein sequence ID" value="SDY40568"/>
        <property type="gene ID" value="SAMN05428934_101645"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05195"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="3">
        <location>
            <begin position="5"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY40568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="418" mass="43422" checksum="83A710D4CC5FC0C1" modified="2017-04-12" version="1">MSTTVVITGIGATTPLGGTAPSTWEALLSGRSGVSLITEDWAADLPTRIAARAAVEPTEIIDRIEARKLDRSTQLVMVAGLEAWADAGFGLGEDNPVDRDRLGVCSATGIGGLHSLLGQWDVMKDKGVRRVSPFTIPMLMANAPAANIGLKIGARAGIHTPISACASSNEAISLGLDTIRLGRADVVMVGGGEAVIHPLPIGAFGQMQALSRRNDEPERASRPWDVDRDGFVLGEGAAMLVLETLEHAQARGAKIYGTLRGAGMTADSHDIVQPDPEGYGQSQAMVKGLREAGLSASDIVHVNAHGTSTPQGDITEAGSIRNALGRDVEHVVVNSTKSMTGHLLGGAGALETLATVLALKNRVVPGTINVDNIEPDLGIDVATENRQLPDGDLAAVNNSFGFGGHNVAVVVTNENITD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDV6</accession>
    <name>A0A1Q2CDV6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Alanine or glycine:cation symporter, AGCS family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Sodium:alanine symporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_05225</name>
        <name evidence="10" type="ORF">SAMN05428934_101651</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY40740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05225"/>
    <dbReference type="EnsemblBacteria" id="AQP44288">
        <property type="protein sequence ID" value="AQP44288"/>
        <property type="gene ID" value="RPIT_05225"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY40740">
        <property type="protein sequence ID" value="SDY40740"/>
        <property type="gene ID" value="SAMN05428934_101651"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05225"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015655">
        <property type="term" value="F:alanine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001463">
        <property type="entry name" value="Na/Ala_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30330">
        <property type="entry name" value="PTHR30330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01235">
        <property type="entry name" value="Na_Ala_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00175">
        <property type="entry name" value="NAALASMPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00835">
        <property type="entry name" value="agcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="243"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="353"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="396"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="422"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY40740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="470" mass="49477" checksum="F6A3CFD004E0D083" modified="2017-04-12" version="1">MQQLQDILDSTASFVWGPLFLIPLLLLTGLWLTVRLRGIQFRTLGSAMRLALWERHDHDAEGGDISHFQALTTALAATVGVGNIVGVATAISIGGPGALFWMWVTGLVGMASKYSEAFLAVRFRTVDDKGEVSGGPQYYLKKALPGQWGVALSIIFAVFAVLASFGIGNMTQGNAVAANMEDAFGVPTQITAIVLAVFVGLVILGGIKVIGRVTAAFVPIMIVLYVLGALFILAVNITDVPGAFALIFGQAFTGQAATGGAIGGLMIAIQMGVARGIFSNESGMGSAAIAAAAAKTTHPVRQGLVSMTQTFIDTIIVVSCTGLVLVTTGVWEADANAAVLTSMAFSTGLPGNWGQYIVALGVVMFASSTILGWSYYGDRCVERLFGARATLAYRIVFTLVVYVGATIPLGIVWSFADVMNGLMALPNLIGLLILSGLIARETAHYLKNDPKLRAGRTEVDDFMADQVREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDW5</accession>
    <name>A0A1Q2CDW5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GntR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04910</name>
        <name evidence="3" type="ORF">SAMN05428934_101590</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY39121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04910"/>
    <dbReference type="EnsemblBacteria" id="AQP44235">
        <property type="protein sequence ID" value="AQP44235"/>
        <property type="gene ID" value="RPIT_04910"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY39121">
        <property type="protein sequence ID" value="SDY39121"/>
        <property type="gene ID" value="SAMN05428934_101590"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04910"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="13"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY39121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="124" mass="13410" checksum="E96925E92B5A2F09" modified="2017-04-12" version="1">MTLVLTLDPDDPTPPYEQLRRQLGDLIAAGRLGPGDRLPPLRQLAGDLGVAVGTVARSYRELEQEGLLTSRRGGGTRVAESGRAPAVNRQEMLEGMAADFVARVRGLGYTDDETVAALERQLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE17</accession>
    <name>A0A1Q2CE17_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05525"/>
    <dbReference type="EnsemblBacteria" id="AQP44341">
        <property type="protein sequence ID" value="AQP44341"/>
        <property type="gene ID" value="RPIT_05525"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05525"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="219" mass="23908" checksum="8838F820C84FF3F3" modified="2017-04-12" version="1">MSSLRPIGQDGNVPELPDGIDIDEATGDMSGAPTTAGTYAVTVTVTDAEGNDASVSFAITVEAADTTPTPPVAEKFQRTIPHTTPGAHTHNGRQGMTTCEPYSRTERCRTEIWASVVKRTGSTFTIERGWAFNNLTYLPFMKREQWAGNPLGYTGYFTGTDQAKWRTECDTEATGSNGCRSYRLTTVYVASPKASGGYTFGQENKWVFNNIVLFGNYTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE32</accession>
    <name>A0A1Q2CE32_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HRDC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05625"/>
    <dbReference type="EnsemblBacteria" id="AQP44357">
        <property type="protein sequence ID" value="AQP44357"/>
        <property type="gene ID" value="RPIT_05625"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05625"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041605">
        <property type="entry name" value="Exo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18305">
        <property type="entry name" value="DNA_pol_A_exoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00570">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="SSF47819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HRDC" evidence="2">
        <location>
            <begin position="251"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="429" mass="46876" checksum="2E57D8CBCBC5448F" modified="2017-04-12" version="1">MAGPRGSGGRPAPLPRRGGPPADRAPLMSYVESSREPLRDLVDTPSALDACLDALSEATGPVAFDTERAHGHRYWPKAYLLQIRREGAGTWLIDPIAFEDGSAAQLGALVAATGDATWLVHAASQDLPSMREVGIIPPAIFDTELAARLLAKPGASLGALLEAELGVKLRKAHSADNWSKRPLPPSWLTYAALDVDYLIELAQVLETELVQARRFDWARQEFAETLERFSRAPEPRIDPWRRLSGVTTLRTPRQYAVARELWRERDAIAAKRDRPPGWILHDSAILAVATAARDQVPGRAELQQLSAFGASQGQRYLTNWLAALDRVARMPESQYPPRRAPRDGLPHPKSWDRINPEAAARWAKVRPAIDILACDLGGLQPSLVAPPAVLQQAVFAHESVTEEILTSLGARPWQAGFLAPAINEALGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE60</accession>
    <name>A0A1Q2CE60_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05810</name>
        <name evidence="3" type="ORF">SAMN05428934_103109</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44388">
        <property type="protein sequence ID" value="AQP44388"/>
        <property type="gene ID" value="RPIT_05810"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67935">
        <property type="protein sequence ID" value="SDY67935"/>
        <property type="gene ID" value="SAMN05428934_103109"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05810"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY67935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="76" mass="7973" checksum="A3328C3096746709" modified="2017-04-12" version="1">MVNTERKASTMSGEISETARMTPRGDADGSGPGQNEQIPPAVDAGHEAQGEPRDYSPGPGSEHPTDRAIADPDEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE83</accession>
    <name>A0A1Q2CE83_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA polymerase-binding protein RbpA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rbpA</name>
        <name evidence="2" type="ORF">RPIT_05975</name>
        <name evidence="3" type="ORF">SAMN05428934_103141</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Bind 1 Zn(2+) per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms a complex with the RNAP catalytic core and with free principal sigma factors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA polymerase-binding protein RbpA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05975"/>
    <dbReference type="EnsemblBacteria" id="AQP44416">
        <property type="protein sequence ID" value="AQP44416"/>
        <property type="gene ID" value="RPIT_05975"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68751">
        <property type="protein sequence ID" value="SDY68751"/>
        <property type="gene ID" value="SAMN05428934_103141"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05975"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001000">
        <property type="term" value="F:bacterial-type RNA polymerase core enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01483">
        <property type="entry name" value="RbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038638">
        <property type="entry name" value="RbpA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025182">
        <property type="entry name" value="RNApol-bd_RbpA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13397">
        <property type="entry name" value="RbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY68751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="113" mass="12878" checksum="1B6E574E32DF8950" modified="2017-04-12" version="1">MADRALRGVGLGSKTFEDEQGIEFAERQELAFDCPKGHHFVVTFSVEAELPTEWECKKCGSLAVRSDGVVGEEKAVKPARTHWDMLRERRSIPELEDILAEQLTKLRESDRIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE84</accession>
    <name>A0A1Q2CE84_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HNH endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_06085</name>
        <name evidence="5" type="ORF">SAMN05428934_103162</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY69248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06085"/>
    <dbReference type="EnsemblBacteria" id="AQP44434">
        <property type="protein sequence ID" value="AQP44434"/>
        <property type="gene ID" value="RPIT_06085"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY69248">
        <property type="protein sequence ID" value="SDY69248"/>
        <property type="gene ID" value="SAMN05428934_103162"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06085"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003870">
        <property type="entry name" value="DUF222"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02720">
        <property type="entry name" value="DUF222"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="3">
        <location>
            <begin position="355"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="238"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="435"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY69248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="468" mass="51254" checksum="49F2280B29C8B5D4" modified="2017-04-12" version="1">MNDTRRSTLAVLEAADQLLSSVDHTQRQTLSCEERVHLMRLARRVVERMATLSHVLIDEVDQANAALPATGTPITSLIALDEHRDNKEAASQVFHASAVNKHEAARDAALAGDISDRHAAAISRAMAELPDGLTPLARKRAEEILVTKAGSHTPRQLGRLAPAVLAEVAPELIPDQSAEANATEARRARAVARRSFQYGDDGDGSVWFRGSLPEAEATPFIRSIEAFVERDRRAARNRERDLRDAGAGPAEFREQRGVDARRTPAQRRADALVELSRHVRDTPTTVGDRPRLVVTVSLDALQSRADGAGILPSGDKLSAGELRRLCCDADLVPVVLGARSEILDVGRSRRLVTPAIRRALSLRDRGCVFPNCDIPDTGCDAHHVVPWIDGGETALSNLALLCPHHHALVEPDRARRREDRWRLWIDEESGRPCIAAPRRLRESGADSRSVSSPPGRQPRREHAHALAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEH4</accession>
    <name>A0A1Q2CEH4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C</fullName>
            <shortName evidence="1">Asp/Glu-ADT subunit C</shortName>
            <ecNumber evidence="1">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gatC</name>
        <name evidence="3" type="ORF">RPIT_06515</name>
        <name evidence="4" type="ORF">SAMN05428934_103248</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14513"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="Rhea" id="RHEA-COMP:9677"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GatC family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06515"/>
    <dbReference type="EnsemblBacteria" id="AQP44506">
        <property type="protein sequence ID" value="AQP44506"/>
        <property type="gene ID" value="RPIT_06515"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71553">
        <property type="protein sequence ID" value="SDY71553"/>
        <property type="gene ID" value="SAMN05428934_103248"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06515"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00122">
        <property type="entry name" value="GatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003837">
        <property type="entry name" value="Asp/Glu-ADT_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036113">
        <property type="entry name" value="Asp/Glu-ADT_sf_sub_c"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02686">
        <property type="entry name" value="Glu-tRNAGln"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141000">
        <property type="entry name" value="SSF141000"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00135">
        <property type="entry name" value="gatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY71553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="97" mass="10266" checksum="71CE226EEB787579" modified="2017-04-12" version="1">MAITADDVARLGALARIQLSEQECAELAPELTVILDSVRSVGEVATPDVPLSTHAVPMTNVFRDDVVRPPLTNGQALSGAPDSEDGRFRVPQILGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEI6</accession>
    <name>A0A1Q2CEI6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycogen debranching enzyme GlgX</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Glycogen operon protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_06545</name>
        <name evidence="6" type="ORF">SAMN05428934_103254</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06545"/>
    <dbReference type="EnsemblBacteria" id="AQP44511">
        <property type="protein sequence ID" value="AQP44511"/>
        <property type="gene ID" value="RPIT_06545"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71714">
        <property type="protein sequence ID" value="SDY71714"/>
        <property type="gene ID" value="SAMN05428934_103254"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06545"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004133">
        <property type="term" value="F:glycogen debranching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005980">
        <property type="term" value="P:glycogen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02856">
        <property type="entry name" value="E_set_GDE_Isoamylase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044505">
        <property type="entry name" value="GlgX_Isoamylase_N_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011837">
        <property type="entry name" value="Glycogen_debranch_GlgX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02100">
        <property type="entry name" value="glgX_debranch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="4">
        <location>
            <begin position="158"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="468"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY71714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="716" mass="79549" checksum="6B4F2892D48D242B" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEK8</accession>
    <name>A0A1Q2CEK8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptide/nickel transport system ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_06835</name>
        <name evidence="6" type="ORF">SAMN05428934_11079</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06835"/>
    <dbReference type="EnsemblBacteria" id="AQP44562">
        <property type="protein sequence ID" value="AQP44562"/>
        <property type="gene ID" value="RPIT_06835"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09677">
        <property type="protein sequence ID" value="SDZ09677"/>
        <property type="gene ID" value="SAMN05428934_11079"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06835"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDZ09677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="257" mass="27386" checksum="E3F23F3C2F9CE65E" modified="2017-04-12" version="1">MSLVELRGAGVTYRRAGKPFVALRDVDLVIGEGERVGIVGGSGSGKTTMARLMLGLQPPAAGDVLFQGRSIVGLPERRRGWLRAAASMVFQDPNSSLNPRMTLRDIVGEPLRSPVLKGRGDVPPLTGQVLTEALAGVGLTPDMLDRFPHQLSGGQRQRVAIARALISDPALLVADEPVSALDVSVRAQVLNLLTDEVNERGLALVLVSHDLAIVRHLCERVVVVDRGSVVEQGEVAQVLEAPRHPYTAALVEATLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEL3</accession>
    <name>A0A1Q2CEL3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP synthase subunit delta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP synthase F(1) sector subunit delta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">F-type ATPase subunit delta</fullName>
            <shortName evidence="6">F-ATPase subunit delta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">atpH</name>
        <name evidence="7" type="ORF">RPIT_06680</name>
        <name evidence="8" type="ORF">SAMN05428934_110111</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="6">This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ATPase delta chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ10228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06680"/>
    <dbReference type="EnsemblBacteria" id="AQP44537">
        <property type="protein sequence ID" value="AQP44537"/>
        <property type="gene ID" value="RPIT_06680"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ10228">
        <property type="protein sequence ID" value="SDZ10228"/>
        <property type="gene ID" value="SAMN05428934_110111"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06680"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="PTHR11910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0139">CF(1)</keyword>
    <keyword evidence="2 6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="3 6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ10228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="264" mass="27658" checksum="F613AB3CE26ACE60" modified="2017-04-12" version="1">MTARDAAIAELDRAVDGLGAGASAAELFAVVDVLDAQPSLRRSLSDPSASDDQRAGLARRLFGGKLGAESVAVIGEVVKAPWGTGQRMASALERQAVRLALKTAVDNGNLADVVAQLNSLAAAVSSSHELNAALRDRSYPVAAKQELIDRLIAGQALPATRTLASRAVKARRRNFTVTLQSYLEMAAGLLGTKIARVTVARPLDQARIDRLKAALEAQTGTPISIQIEVDPAVIGGLSVAIGDDVIESTVAGRLEQARRQLINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CET0</accession>
    <name>A0A1Q2CET0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07260"/>
    <dbReference type="EnsemblBacteria" id="AQP44632">
        <property type="protein sequence ID" value="AQP44632"/>
        <property type="gene ID" value="RPIT_07260"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07260"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="85" mass="9306" checksum="240A04E9065CFCA8" modified="2017-04-12" version="1">MVNVTLVTTPACHFCDDAHQRLHDLERAGLLRLTAVPAESPQGEALIAEHRPGSFPLTLVAGRYFHAGRIPRGKLARLVDRLGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEU1</accession>
    <name>A0A1Q2CEU1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding transcriptional regulator, FrmR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_07310</name>
        <name evidence="5" type="ORF">SAMN05428934_11419</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CsoR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000014">
        <property type="protein sequence ID" value="SDZ18122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07310"/>
    <dbReference type="EnsemblBacteria" id="AQP44639">
        <property type="protein sequence ID" value="AQP44639"/>
        <property type="gene ID" value="RPIT_07310"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ18122">
        <property type="protein sequence ID" value="SDZ18122"/>
        <property type="gene ID" value="SAMN05428934_11419"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07310"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003735">
        <property type="entry name" value="Metal_Tscrpt_repr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038390">
        <property type="entry name" value="Metal_Tscrpt_repr_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33677">
        <property type="entry name" value="PTHR33677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02583">
        <property type="entry name" value="Trns_repr_metal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ18122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="93" mass="10059" checksum="A812262E3BE83494" modified="2017-04-12" version="1">MTGNPQRPELIGQLAVIEGHIRGIARMVYQDANCIEILTQTSAVTGSLRSVALDLVDNHLQHCLTQAIHSPDPAYRDAKVAEASTAIARLVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEU7</accession>
    <name>A0A1Q2CEU7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CBM6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_07335</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07335"/>
    <dbReference type="EnsemblBacteria" id="AQP44644">
        <property type="protein sequence ID" value="AQP44644"/>
        <property type="gene ID" value="RPIT_07335"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07335"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006584">
        <property type="entry name" value="Cellulose-bd_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003305">
        <property type="entry name" value="CenC_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005084">
        <property type="entry name" value="CMB_fam6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02018">
        <property type="entry name" value="CBM_4_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03422">
        <property type="entry name" value="CBM_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00606">
        <property type="entry name" value="CBD_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51175">
        <property type="entry name" value="CBM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012546543" description="CBM6 domain-containing protein" evidence="5">
        <location>
            <begin position="20"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="domain" description="CBM6" evidence="6">
        <location>
            <begin position="733"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="868"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="875"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="891"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="3">
        <location>
            <position position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="1047" mass="113310" checksum="7D08434E0E8EE822" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEX9</accession>
    <name>A0A1Q2CEX9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA_16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07445"/>
    <dbReference type="EnsemblBacteria" id="AQP44663">
        <property type="protein sequence ID" value="AQP44663"/>
        <property type="gene ID" value="RPIT_07445"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07445"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_16" evidence="1">
        <location>
            <begin position="28"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="427" mass="47313" checksum="4982D62CCA328B4C" modified="2017-04-12" version="1">MTEMSYRVEQVFTPTSQAVLNFVPRAGLDAAVKDALSTPGKQIVVYGESGSGKTTLLRQCVKSYHAGWITTSCHAETTFSDLLLDAFDQLDLYYAESHGSATKQAFGTTLEAQFLQAKSAVQASLEESATTGHKRIVVPQISPQRLAKWMGEKDLCWIIEDFHKVREVEKKALAQAFKIFSDMAMDYPAVRIVAIGATDSAREVVAYENEMRNRVAEIHVPLMDIGELRGILRGGDSLLNIDSSQISHDIVNFSSGLASVTHHLALNACRAAKIRSTQAIKKRLLEAELQSAVLTYIAESSDTLKARYELALKRERERKYHNTELIIRALARGPQEGLSHAQVLADIRRENPEYPSSNVTLYLQKLQSEDRGALIRRTSAGLFRFIDPLFHSYARARMNPELAAPGSGWSAAFSAVIREAVAMIAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF05</accession>
    <name>A0A1Q2CF05_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antitoxin</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Ribbon-helix-helix protein, copG family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07605</name>
        <name evidence="3" type="ORF">SAMN05428934_1213</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000021">
        <property type="protein sequence ID" value="SDZ22626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44688">
        <property type="protein sequence ID" value="AQP44688"/>
        <property type="gene ID" value="RPIT_07605"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ22626">
        <property type="protein sequence ID" value="SDZ22626"/>
        <property type="gene ID" value="SAMN05428934_1213"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07605"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002145">
        <property type="entry name" value="CopG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01402">
        <property type="entry name" value="RHH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RHH_1" evidence="1">
        <location>
            <begin position="40"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ22626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="76" mass="8485" checksum="2BECCE62E2B4DCEF" modified="2017-04-12" version="1">MSDEQIQKWADEAERGYDVDQLKRRGRGRPGRGAEPMQVVAVRLTSEELEALDAAAAKSHMTRSEAIRFALTHFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF11</accession>
    <name>A0A1Q2CF11_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07650</name>
        <name evidence="2" type="ORF">SAMN05428934_12111</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000021">
        <property type="protein sequence ID" value="SDZ22780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44696">
        <property type="protein sequence ID" value="AQP44696"/>
        <property type="gene ID" value="RPIT_07650"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ22780">
        <property type="protein sequence ID" value="SDZ22780"/>
        <property type="gene ID" value="SAMN05428934_12111"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07650"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ22780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="76" mass="8213" checksum="97C7BD450DE5FF61" modified="2017-04-12" version="1">MPNIQIKDVPDDTHAVLRQRASAAHQSLQEYLRSKLIAEAAQPTLDEVLARAGGRAGGSLPLADAVSALRFDRARH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF37</accession>
    <name>A0A1Q2CF37_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07830</name>
        <name evidence="2" type="ORF">SAMN05428934_1136</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07830"/>
    <dbReference type="EnsemblBacteria" id="AQP44726">
        <property type="protein sequence ID" value="AQP44726"/>
        <property type="gene ID" value="RPIT_07830"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16100">
        <property type="protein sequence ID" value="SDZ16100"/>
        <property type="gene ID" value="SAMN05428934_1136"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07830"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ16100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="152" mass="17452" checksum="9C8119808EF5E460" modified="2017-04-12" version="1">MTWIPAEVEPPSRVDLPTGHHLRPIRESDIDIDYPAVMGSRERLWEKYGEAWGWPLATMTREEDQADLARHEAEIAAKETFNYAVLPEGEDRLLGCVYLDPPEDDCPPGTDVLTSWWVVDDEAGGELEKALDEFVPRWLRDVWGFRQPHVDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF61</accession>
    <name>A0A1Q2CF61_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44700">
        <property type="protein sequence ID" value="AQP44700"/>
        <property type="gene ID" value="RPIT_07680"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07680"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="155" mass="17817" checksum="A1A6206385883098" modified="2017-04-12" version="1">MTTRTVENHVNVPAAASDVWDRAVNPDGINFEMRPWMTMSMPPGAAGLSVEDIPLGQPVGRAWLRLFGLIPFDFDRLTIVELESGRRFLERSTMLSMRCWEHERTLTPVAGGTRVHDRVTFRPRLPIPGLAALLERVVHAFFRHRHRRLQEYFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF75</accession>
    <name>A0A1Q2CF75_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SMC-Scp complex subunit ScpB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Segregation and condensation protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_08035</name>
        <name evidence="5" type="ORF">SAMN05428934_11348</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08035"/>
    <dbReference type="EnsemblBacteria" id="AQP44761">
        <property type="protein sequence ID" value="AQP44761"/>
        <property type="gene ID" value="RPIT_08035"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16927">
        <property type="protein sequence ID" value="SDZ16927"/>
        <property type="gene ID" value="SAMN05428934_11348"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08035"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051304">
        <property type="term" value="P:chromosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005234">
        <property type="entry name" value="ScpB_csome_segregation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34298">
        <property type="entry name" value="PTHR34298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04079">
        <property type="entry name" value="SMC_ScpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019345">
        <property type="entry name" value="ScpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ16927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="198" mass="20843" checksum="FADBCC481A93279D" modified="2017-04-12" version="1">MSLTAALEAMLLMATDPVPTDELAAALSAPSAEVEAELEAIAGFYDEHERGLRLRRIAGGWRFATDPSVADVIEGWLVSDQRARLTQAALETLAVVAYLQPVSRGRIAAVRGVNVDGVVKTLLVRGLIQEAGEDPVTGAMTFGTTALFLQKLGLNSLRELPDLAPLLPDAVALEAELGQLAAESTAAAAEAQPKENDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF83</accession>
    <name>A0A1Q2CF83_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ISL3 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44776">
        <property type="protein sequence ID" value="AQP44776"/>
        <property type="gene ID" value="RPIT_08160"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08160"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002560">
        <property type="entry name" value="Transposase_DDE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01610">
        <property type="entry name" value="DDE_Tnp_ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_ISL3" evidence="1">
        <location>
            <begin position="164"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="436" mass="49054" checksum="3D8841E1B86D0242" modified="2017-04-12" version="1">MRARRGGGPDLTAFCRLDELGFVVTGQRLEPDRAVLACQVVGPDQWCWRCGCEGRPRDTVVRRLAHEPLGWRPTTLEVVVRRYRCSGCGYVWRQDTTAAAEPRAKLSRRALRWALEGIVVQHLTVARVAEGLGVAWDTANDAVLAEGRRVLIDEEHRFEGVKVVGVDEHVWRRTRRGDRYVTVIIDLTPVRVGTGPARLLDMVEGRSKQAFKTWLADRPQEWRDGVEVVAMDGFTGFKTAAVEELPDVVTVLDPFHVTRLADEALDECRRRVQQAICGHRGRKGDPLYAARRTLSTGADLLNDKQKDRLDTLFADDAHVEVEVTWSVYQRMIAAYRHENRRHGRELMARLIDSISTGVPKALVEITKLGRTLKKRAADVLAYFDRPSTSNGPTEAINGRLEHLRGSALGFRNLTNYIARSLLETGGFRPRLHPGFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFA4</accession>
    <name>A0A1Q2CFA4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">ATP phosphoribosyltransferase</fullName>
            <shortName evidence="11">ATP-PRT</shortName>
            <shortName evidence="11">ATP-PRTase</shortName>
            <ecNumber evidence="4 11">2.4.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">hisG</name>
        <name evidence="14" type="ORF">RPIT_08300</name>
        <name evidence="15" type="ORF">SAMN05428934_11515</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1T</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1</strain>
        </source>
    </reference>
    <reference evidence="14" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP</text>
            <dbReference type="Rhea" id="RHEA:18473"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="2.4.2.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="11">Feedback inhibited by histidine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the ATP phosphoribosyltransferase family. Long subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.17" evidence="4 11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08300"/>
    <dbReference type="EnsemblBacteria" id="AQP44799">
        <property type="protein sequence ID" value="AQP44799"/>
        <property type="gene ID" value="RPIT_08300"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19305">
        <property type="protein sequence ID" value="SDZ19305"/>
        <property type="gene ID" value="SAMN05428934_11515"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08300"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003879">
        <property type="term" value="F:ATP phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00079">
        <property type="entry name" value="HisG_Long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013820">
        <property type="entry name" value="ATP_PRibTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018198">
        <property type="entry name" value="ATP_PRibTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001348">
        <property type="entry name" value="ATP_PRibTrfase_HisG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020621">
        <property type="entry name" value="ATP_PRibTrfase_HisG_long"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013115">
        <property type="entry name" value="HisG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403">
        <property type="entry name" value="PTHR21403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01634">
        <property type="entry name" value="HisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08029">
        <property type="entry name" value="HisG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00070">
        <property type="entry name" value="hisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03455">
        <property type="entry name" value="HisG_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01316">
        <property type="entry name" value="ATP_P_PHORIBOSYLTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HisG" evidence="12">
        <location>
            <begin position="54"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="HisG_C" evidence="13">
        <location>
            <begin position="211"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="AQP44799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="SDZ19305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="286" mass="30724" checksum="BCAA34B493FC2051" modified="2017-04-12" version="1">MTTDRLLRIAVPNKGALAEPAAAMLKAAGYRQRTDAKDLTLIDSDHGVEFYYLRPRDIAVYIGRGHLDLGITGRDMLLDSRAEATEIMELGFAGSRFLFAAPGGSSMTIADIEGKRVATSYPDLLAGYFEDKGINAELVKLDGAVESAIRLGVADVVADVVDTGTTLKRAGLELFGDPICTSEAVLIQRNNAELPATAEGLKTRLRSVLVAQNFFMMDYNVDTEHLETTLALAPGVEGPTVSTLAKSGWSAVRVLVPRKGAHLLMDRLYEAGARGILLTELAACRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFB4</accession>
    <name>A0A1Q2CFB4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase</fullName>
            <shortName evidence="8">L-Cys:GlcN-Ins ligase</shortName>
            <ecNumber evidence="8">6.3.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Mycothiol ligase</fullName>
            <shortName evidence="8">MSH ligase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mshC</name>
        <name evidence="10" type="ORF">RPIT_08310</name>
        <name evidence="11" type="ORF">SAMN05428934_11513</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + ATP + L-cysteine = 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:26176"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58886"/>
            <dbReference type="ChEBI" id="CHEBI:58887"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 8">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.13" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08310"/>
    <dbReference type="EnsemblBacteria" id="AQP44801">
        <property type="protein sequence ID" value="AQP44801"/>
        <property type="gene ID" value="RPIT_08310"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19267">
        <property type="protein sequence ID" value="SDZ19267"/>
        <property type="gene ID" value="SAMN05428934_11513"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08310"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035446">
        <property type="term" value="F:cysteine-glucosaminylinositol ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010125">
        <property type="term" value="P:mycothiol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01697">
        <property type="entry name" value="MshC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017812">
        <property type="entry name" value="Mycothiol_ligase_MshC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="PTHR10890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03447">
        <property type="entry name" value="mycothiol_MshC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-synt_1e" evidence="9">
        <location>
            <begin position="41"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Cysteinyl adenylate binding" evidence="8">
        <location>
            <begin position="48"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Cysteinyl adenylate binding" evidence="8">
        <location>
            <begin position="86"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Cysteinyl adenylate binding" evidence="8">
        <location>
            <begin position="254"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="293"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>L-cysteinyl-5'-AMP</name>
            <dbReference type="ChEBI" id="CHEBI:144924"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>L-cysteinyl-5'-AMP</name>
            <dbReference type="ChEBI" id="CHEBI:144924"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>L-cysteinyl-5'-AMP</name>
            <dbReference type="ChEBI" id="CHEBI:144924"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00007723"/>
        </source>
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        <source>
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        </source>
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        <source>
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        <source>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_01697"/>
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        <source>
            <dbReference type="Pfam" id="PF01406"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP44801.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDZ19267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="416" mass="45602" checksum="732C56307809046B" modified="2017-04-12" version="1">MYAWAPVAVPSLPKSDDSVPGRLTLFDTAAQSLTEVGPNDGAARMYVCGITPYDATHLGHANTYVTFDLVQRVWLDLGLDVDYTQNVTDVDDPLLERAAETGQEWEELAEDQIELFRSDMQDLRVIPPRHYIGAVESISCVIDLIEQLLPSGLVYQVDDDQHPDWYFNTVGAEGFGGVSNLDESRMIELFRENGGDPDRPGKRHPLDCLVWRFARPDEPSWTSSLGAGRPGWHIECTAIAMRYLGPNFDVQGGGSDLVFPHHEMCAAEAIAAAHEPMAEAFVHSGMVGLDGEKMSKSKGNLELVSRLRHAGADPMAIRLALMDNHYRSNWDWTPDKLERATERLTAWRGVLNNATAMPAGETIAAMRTALRNDLNAPAALATVDAWVAASMAIESDDTSAVSDMVQAIDALLGIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFI9</accession>
    <name>A0A1Q2CFI9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein-disulfide isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_08780</name>
        <name evidence="5" type="ORF">SAMN05428934_10766</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08780"/>
    <dbReference type="EnsemblBacteria" id="AQP44873">
        <property type="protein sequence ID" value="AQP44873"/>
        <property type="gene ID" value="RPIT_08780"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97652">
        <property type="protein sequence ID" value="SDY97652"/>
        <property type="gene ID" value="SAMN05428934_10766"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Thioredoxin-like_fold"/>
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        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13462">
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    </dbReference>
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        <property type="entry name" value="SSF52833"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
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        <location>
            <begin position="87"/>
            <end position="235"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF13462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY97652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="269" mass="29192" checksum="8E446FA3B742A8A4" modified="2017-04-12" version="1">MANNSSLSKRAALRQQQEMEERSKRNKRILTIGGAIAAITVIAVIAIVAIQAMGRGVGMAEEQLTPPNATEGYGVLVGGKSPVEGTPHLIIYEDFQCPACAAREAEYGPAVDQLVANGDITAEFRFAYFLDGAGREGGASHRAALAAAAADQVGAFDEYHKVVYANQSNSGGYSDSKLRDEFAEQAGITGEDLDEFKRLYNTKAFWDFTKNANQKFNDEEIGSTPTYQVSGEKLEFYDQNSQQVLIQPTPDDMLRAITEAYEAGGQEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFM5</accession>
    <name>A0A1Q2CFM5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA ligase</fullName>
            <ecNumber evidence="8">6.5.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Polydeoxyribonucleotide synthase [NAD(+)]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ligA</name>
        <name evidence="10" type="ORF">RPIT_08925</name>
        <name evidence="11" type="ORF">SAMN05428934_10798</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the NAD-dependent DNA ligase family. LigA subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.2" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08925"/>
    <dbReference type="EnsemblBacteria" id="AQP44897">
        <property type="protein sequence ID" value="AQP44897"/>
        <property type="gene ID" value="RPIT_08925"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98224">
        <property type="protein sequence ID" value="SDY98224"/>
        <property type="gene ID" value="SAMN05428934_10798"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08925"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003911">
        <property type="term" value="F:DNA ligase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00114">
        <property type="entry name" value="LIGANc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01588">
        <property type="entry name" value="DNA_ligase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041663">
        <property type="entry name" value="DisA/LigA_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033136">
        <property type="entry name" value="DNA_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001679">
        <property type="entry name" value="DNAligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013839">
        <property type="entry name" value="DNAligase_adenylation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013840">
        <property type="entry name" value="DNAligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004150">
        <property type="entry name" value="NAD_DNA_ligase_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004149">
        <property type="entry name" value="Znf_DNAligase_C4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01653">
        <property type="entry name" value="DNA_ligase_aden"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03120">
        <property type="entry name" value="DNA_ligase_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03119">
        <property type="entry name" value="DNA_ligase_ZBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12826">
        <property type="entry name" value="HHH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001604">
        <property type="entry name" value="LigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00532">
        <property type="entry name" value="LIGANc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="SSF52113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00575">
        <property type="entry name" value="dnlj"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01056">
        <property type="entry name" value="DNA_LIGASE_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2 8" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="BRCT" evidence="9">
        <location>
            <begin position="603"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="active site" description="N6-AMP-lysine intermediate" evidence="8">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="44"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="93"/>
            <end position="94"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="411"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="414"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="430"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="436"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY98224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="694" mass="74630" checksum="2E50D0D69540F241" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFN4</accession>
    <name>A0A1Q2CFN4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Formamidopyrimidine-DNA glycosylase</fullName>
            <shortName evidence="15">Fapy-DNA glycosylase</shortName>
            <ecNumber evidence="15">3.2.2.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">DNA-(apurinic or apyrimidinic site) lyase MutM</fullName>
            <shortName evidence="15">AP lyase MutM</shortName>
            <ecNumber evidence="15">4.2.99.18</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">mutM</name>
        <name evidence="15" type="synonym">fpg</name>
        <name evidence="19" type="ORF">RPIT_08680</name>
        <name evidence="20" type="ORF">SAMN05428934_10746</name>
    </gene>
    <organism evidence="19 21">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 21" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 21">RP1T</strain>
        </source>
    </reference>
    <reference evidence="20 22" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 22">RP1</strain>
        </source>
    </reference>
    <reference evidence="19" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine.</text>
            <dbReference type="EC" id="3.2.2.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="15">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 15">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the FPG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.23" evidence="15"/>
    <dbReference type="EC" id="4.2.99.18" evidence="15"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08680"/>
    <dbReference type="EnsemblBacteria" id="AQP44855">
        <property type="protein sequence ID" value="AQP44855"/>
        <property type="gene ID" value="RPIT_08680"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97188">
        <property type="protein sequence ID" value="SDY97188"/>
        <property type="gene ID" value="SAMN05428934_10746"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08680"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008534">
        <property type="term" value="F:oxidized purine nucleobase lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00103">
        <property type="entry name" value="Fapy_DNA_glycosyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015886">
        <property type="entry name" value="DNA_glyclase/AP_lyase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015887">
        <property type="entry name" value="DNA_glyclase_Znf_dom_DNA_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020629">
        <property type="entry name" value="Formamido-pyr_DNA_Glyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012319">
        <property type="entry name" value="FPG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035937">
        <property type="entry name" value="MutM-like_N-ter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000214">
        <property type="entry name" value="Znf_DNA_glyclase/AP_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010663">
        <property type="entry name" value="Znf_FPG/IleRS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01149">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06831">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06827">
        <property type="entry name" value="zf-FPG_IleRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00898">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01232">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81624">
        <property type="entry name" value="SSF81624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00577">
        <property type="entry name" value="fpg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51068">
        <property type="entry name" value="FPG_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01242">
        <property type="entry name" value="ZF_FPG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51066">
        <property type="entry name" value="ZF_FPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9 15" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="13 15" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 15 20" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 15 16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FPG_CAT" evidence="18">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="FPG-type" evidence="17">
        <location>
            <begin position="239"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with DNA" evidence="15">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="15">
        <location>
            <position position="3"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for beta-elimination activity" evidence="15">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for delta-elimination activity" evidence="15">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>DNA</name>
            <dbReference type="ChEBI" id="CHEBI:16991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>DNA</name>
            <dbReference type="ChEBI" id="CHEBI:16991"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00024490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="AQP44855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="SDY97188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="279" mass="31155" checksum="54674406AA05A1DA" modified="2017-04-12" version="1">MPELPEVEVVRRGLAAHTVGRRIERVTVLHPRPVRSHPAGPDGFVADLAGRAVDDVRRRGKYLWLALGDDALVVHLGMSGQFRLGHATDDLVRNTRVLFDLDDGRQLRFVDQRMFGGLQYSPGTAACPVPHIALDPFDPEFDERAVAARLRTRRTGVKRALLDQSLVSGIGNIYADESLWRTRVHYEHPSDELGPRKAVELIRTARDVMDEALQQGGTSFDSLYVNVNGESGYFGRALTAYGREGEPCQRCGTPIVRRAFMNRSSFLCPRCQRLPGRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFQ4</accession>
    <name>A0A1Q2CFQ4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tricorn protease homolog</fullName>
            <ecNumber evidence="7">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_08790</name>
        <name evidence="13" type="ORF">SAMN05428934_10768</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Degrades oligopeptides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the peptidase S41B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08790"/>
    <dbReference type="EnsemblBacteria" id="AQP44875">
        <property type="protein sequence ID" value="AQP44875"/>
        <property type="gene ID" value="RPIT_08790"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97693">
        <property type="protein sequence ID" value="SDY97693"/>
        <property type="gene ID" value="SAMN05428934_10768"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08790"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028204">
        <property type="entry name" value="Tricorn_C1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029414">
        <property type="entry name" value="Tricorn_PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012393">
        <property type="entry name" value="Tricorn_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43253">
        <property type="entry name" value="PTHR43253"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14684">
        <property type="entry name" value="Tricorn_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14685">
        <property type="entry name" value="Tricorn_PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036421">
        <property type="entry name" value="Tricorn_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7 13" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="TSPc" evidence="11">
        <location>
            <begin position="821"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="516"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="526"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="736"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="956"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="1014"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer; via amide nitrogen" evidence="9">
        <location>
            <position position="957"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
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        <source>
            <dbReference type="PIRNR" id="PIRNR036421"/>
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    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR036421-1"/>
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        <source>
            <dbReference type="PIRSR" id="PIRSR036421-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP44875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY97693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="1067" mass="116716" checksum="D51FC1BAB8917904" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFR8</accession>
    <name>A0A1Q2CFR8_9ACTN</name>
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        <submittedName>
            <fullName evidence="5">Glycosyl transferase family 1</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Glycosyltransferase involved in cell wall bisynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_09305</name>
        <name evidence="6" type="ORF">SAMN05428934_102448</name>
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    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="AQP44959">
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    </dbReference>
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        <property type="gene ID" value="SAMN05428934_102448"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProt"/>
    </dbReference>
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        <location>
            <begin position="20"/>
            <end position="176"/>
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            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
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            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF13439"/>
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    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY61041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="359" mass="38663" checksum="F0BEE1B051F7EAA2" modified="2017-04-12" version="1">MIRRIAVIAGSRYPIRAPFAGGMESITWHLVEGMRRRGVPITLFAAPGSDPQLQAETIEVEPLVLSDAARADVAMPPEKTLREHHAYLQVMLELGRRDLDVVHNNSLHYLPIVMAELLSAPMVTTLHTPPTPWLEPAARIANAADIRYAAVSAATAEQWSGIVEATVIPNGVDLDQWAYGDGGDSLVWTGRIVPEKAPHLAIAIAEATGRRLRIAGPRPDPGYWGTFIKPHLGDLVTYEGHLTGHQLAELIGTSAAALVTPVWDEPYGLVAAEALACGTPVLAIARGGLPEVVGHDCGRLIEPGTEEAMIAAGASLLSETMALPRAAARRHAVEHCSLNVMIDRYLALYEELSTRRRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG37</accession>
    <name>A0A1Q2CG37_9ACTN</name>
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        <submittedName>
            <fullName evidence="2">Acyl-CoA carboxylase epsilon subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_09660</name>
        <name evidence="2" type="ORF">SAMN05428934_102373</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP45020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY59030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45020">
        <property type="protein sequence ID" value="AQP45020"/>
        <property type="gene ID" value="RPIT_09660"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59030">
        <property type="protein sequence ID" value="SDY59030"/>
        <property type="gene ID" value="SAMN05428934_102373"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09660"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004658">
        <property type="term" value="F:propionyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032716">
        <property type="entry name" value="ACC_epsilon"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13822">
        <property type="entry name" value="ACC_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY59030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="71" mass="7730" checksum="3FBBD928E8DB132F" modified="2017-04-12" version="1">MSEQPALQITGATLTEEEAAAVVAVLTAASRGETLRSADDRPIAGGWGSYYRTVRSHLVTGRDAWRTFHRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG45</accession>
    <name>A0A1Q2CG45_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_10070</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DyP-type peroxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10070"/>
    <dbReference type="EnsemblBacteria" id="AQP45092">
        <property type="protein sequence ID" value="AQP45092"/>
        <property type="gene ID" value="RPIT_10070"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10070"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006314">
        <property type="entry name" value="Dyp_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04261">
        <property type="entry name" value="Dyp_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01413">
        <property type="entry name" value="Dyp_perox_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51404">
        <property type="entry name" value="DYP_PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010375172" evidence="4">
        <location>
            <begin position="34"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="404" mass="42399" checksum="3FB32B7F6BF55688" modified="2017-04-12" version="1">MTPPDVSRRSVFGYAGAAGIAGAAGIVAGRASASPASGEQLDSPRSGVVGQSYSPYGEHQAGIFTGKPAAGELVALDLLAGTDKAALGRLMRVWSPTIAALAEGRPVPGDTTPDLAQPGVSMTVLVGLGPRIFDLEGLSARRPAGFQEIPPMDHDQLQSRWSGGDLLVWVSADDATSVSYAVRRLVADAAPFAKRRWSQPGNWRPVDASGAAITGRNHFGQVDGSHNPTGDELLTAVISGDDWLAGGTQLVIRRIEMHMDTWDELTRDRQEASIGRDLASGAPLTGGGELDDVDLDAVVDGAPAIPLDAHVRVSHPAENSGRQMLRRALNYTHEEWVDGAPVTTAGLIFTAFQASIADQFIPVQRKLDVGDALNEWTTAIGSAVFVIPPGFSADSYLAKGLLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG46</accession>
    <name>A0A1Q2CG46_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uridine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09725</name>
        <name evidence="4" type="ORF">SAMN05428934_102360</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY58676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09725"/>
    <dbReference type="EnsemblBacteria" id="AQP45030">
        <property type="protein sequence ID" value="AQP45030"/>
        <property type="gene ID" value="RPIT_09725"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY58676">
        <property type="protein sequence ID" value="SDY58676"/>
        <property type="gene ID" value="SAMN05428934_102360"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09725"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PRK" evidence="2">
        <location>
            <begin position="8"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY58676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="202" mass="22179" checksum="D202B0A136BB3C14" modified="2017-04-12" version="1">MTRTLLLIAGPSGSGKSRLTRTAVTHGRAASLSLDDFYFDADHPDLPTTPMGIPDWDDPATWDLQLAITTLGQLLRDGAAEVPVYDISRSRRVGVRRIELGDSDLVIAEGIFATQTCPAARAAGMRVEALWLDRARPANFVRRLSRDLRERRKTPWVLLRRGIALYRGEPQQRRAALEAGFSPASMSQAMRAVSRAADAAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG61</accession>
    <name>A0A1Q2CG61_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Magnesium transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">PRC-barrel domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_10120</name>
        <name evidence="4" type="ORF">SAMN05428934_102281</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10120"/>
    <dbReference type="EnsemblBacteria" id="AQP45101">
        <property type="protein sequence ID" value="AQP45101"/>
        <property type="gene ID" value="RPIT_10120"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56438">
        <property type="protein sequence ID" value="SDY56438"/>
        <property type="gene ID" value="SAMN05428934_102281"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10120"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006668">
        <property type="entry name" value="Mg_transptr_MgtE_intracell_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038076">
        <property type="entry name" value="MgtE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006669">
        <property type="entry name" value="MgtE_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43773">
        <property type="entry name" value="PTHR43773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03448">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00924">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="351"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY56438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="424" mass="46790" checksum="D0C8613730A21011" modified="2017-04-12" version="1">MVAKDSQVFISRVIGLPIVDAAGDQVGRVKDVVCYLRTDGKAPRVKGLVVELFARARIFMPIIRVRDITPNQVAILGQVDTRKFQRRESEILVAADLFDRSIERTNRTKILDVSMHQVRNREWELLSVALRTTTGVGRFGLGGRTPPKVVGWREIPELILKTGRTAAHLVAEFSDMKAADVARELHDLEPESLAAVVDALDDETLAEAIEELPEDEQIELISQMDTARAADILSEMDPDDAADLIKDLPQDVAEDLLQRMEPEDASDVRRLLVYEEFTAGGMMTPEPIILDTGATVAEALAHAREESLTPALASMVFVTRPPLETPSGRYVGAVHFQRLLREPPTTLVVNMLDDNLEPLHPQAPLAQVSRFLATYNMVVAPVVNDDGALVGAVTVDDVLDHMLPDDWRGDQMDRPATEVNHGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG92</accession>
    <name>A0A1Q2CG92_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_10000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45080">
        <property type="protein sequence ID" value="AQP45080"/>
        <property type="gene ID" value="RPIT_10000"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10000"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
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</entry>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
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    </evidence>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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    </dbReference>
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        <location>
            <begin position="1"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="115"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="47"/>
            <end position="63"/>
        </location>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
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            <dbReference type="EMBL" id="AQP45304.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY49484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="241" mass="23616" checksum="E3560E9EBEB220CC" modified="2017-04-12" version="1">MNRERAAGRIVAAVAVLVAVAAVVAVLALSGGNSVPSPGPTVAPSLEPSASALTTPSDGVTQPDVTATTVDALTPSESLAASWTQTTQAASGPEVMSASEAPPPGAATEALDPDASAKAELSAADTLPSGQLALEDLPSTVGLWSADDELGPVAYTKAGGSPEDTITVTSLGADSMGLDHWRSSMTDATAIDGGLCGLVGGVAACVLPSQRYGEVMLFGTDGVGVADVREVATGVSSAVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGS7</accession>
    <name>A0A1Q2CGS7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.60</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">4-diphosphocytidyl-2C-methyl-D-erythritol synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">MEP cytidylyltransferase</fullName>
            <shortName evidence="7">MCT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ispD</name>
        <name evidence="8" type="ORF">RPIT_11295</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>2-C-methyl-D-erythritol 4-phosphate + CTP + H(+) = 4-CDP-2-C-methyl-D-erythritol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13429"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:57823"/>
            <dbReference type="ChEBI" id="CHEBI:58262"/>
            <dbReference type="EC" id="2.7.7.60"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 2/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.60" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11295"/>
    <dbReference type="EnsemblBacteria" id="AQP45307">
        <property type="protein sequence ID" value="AQP45307"/>
        <property type="gene ID" value="RPIT_11295"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11295"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00093"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050518">
        <property type="term" value="F:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02516">
        <property type="entry name" value="CDP-ME_synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00108">
        <property type="entry name" value="IspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001228">
        <property type="entry name" value="IspD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034683">
        <property type="entry name" value="IspD/TarI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018294">
        <property type="entry name" value="ISPD_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01128">
        <property type="entry name" value="IspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00453">
        <property type="entry name" value="ispD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01295">
        <property type="entry name" value="ISPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5 7 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0808">Transferase</keyword>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="23"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <feature type="site" description="Positions MEP for the nucleophilic attack" evidence="7">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <feature type="site" description="Positions MEP for the nucleophilic attack" evidence="7">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="235" mass="23801" checksum="CA802DB8D16EC0F7" modified="2017-04-12" version="1">MTPVHSTDQPVVAVLVAAGSGSRLGAAVPKALVELAGVPLVRLSAEALVAGGVQQVVVTIPGGMDAPFEQALAGLRAPLRIVAGGSTRQESVRLGLKALNASDDAVVLVHDAARALVPPALVASVVEAIADGAAAAVPVLPVTDSIRQLTASGSVVVDRSALRAVQTPQAARLGALRDAHEHARVRGLEVTDDAAVCELVGLDVTLVPGHSDAMKVTTPADLVVATAILEERRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGU8</accession>
    <name>A0A1Q2CGU8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CAAX protease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11450</name>
        <name evidence="3" type="ORF">SAMN05428934_10213</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY48347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11450"/>
    <dbReference type="EnsemblBacteria" id="AQP45336">
        <property type="protein sequence ID" value="AQP45336"/>
        <property type="gene ID" value="RPIT_11450"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY48347">
        <property type="protein sequence ID" value="SDY48347"/>
        <property type="gene ID" value="SAMN05428934_10213"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11450"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY48347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="242" mass="25411" checksum="0911AFEA1A1942A5" modified="2017-04-12" version="1">MPIPTVVREVRAFLSASLVRPVERQRDETPESRRRRRIVVGVTLVIGAVALGLALAVRPGDPLFYAATLGVAAIWTVGALVSGPLHLGEGHTRDGGRSRGVVQGILLGLGLMGIFLAGALVVEQIPLLRGPVLDLLDHARFGSLWVVALVTVINGIAEELFFRGAVYASLDSRFNGIGSTLLYAASTLFSGVPLLTFAALCLGLLTAAQRRVTGGVLGPIASHLTWSLGMLFLLPPILTPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGY7</accession>
    <name>A0A1Q2CGY7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Levanase/fructan beta-fructosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_11630</name>
        <name evidence="4" type="ORF">SAMN05428934_106149</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 32 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11630"/>
    <dbReference type="EnsemblBacteria" id="AQP45367">
        <property type="protein sequence ID" value="AQP45367"/>
        <property type="gene ID" value="RPIT_11630"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93925">
        <property type="protein sequence ID" value="SDY93925"/>
        <property type="gene ID" value="SAMN05428934_106149"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11630"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001362">
        <property type="entry name" value="Glyco_hydro_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018053">
        <property type="entry name" value="Glyco_hydro_32_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013148">
        <property type="entry name" value="Glyco_hydro_32_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00251">
        <property type="entry name" value="Glyco_hydro_32N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00640">
        <property type="entry name" value="Glyco_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00609">
        <property type="entry name" value="GLYCOSYL_HYDROL_F32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_32N" evidence="2">
        <location>
            <begin position="12"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY93925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="448" mass="48943" checksum="573BBF282CA21018" modified="2017-04-12" version="1">MHDTPHYRPELHFTPEGTWMNDPNGLLFHKGRYHLFFQNNPTGRTWGNISWGHAVSTDLLTWEELPVAIPATAEEMAFSGSVVWDRLNTSGLGDGPEGPLVALFTSSYTALDPSRPGQQAQSIAYSVDDGLTWTRYDRNPVLERGSSDFRDPKVSWHEPSGRWVMVTVEAVDRQVLIHSSADLLTWTHESSVGPLGEEGLLWECPDLVEVPVEGTATSRWVLLLSTNPGGFSGGSGMRYLVGDFDGASFAPDEAGWRWLDYGPDFYAAVSFHGLRDPLILGWMSNWSYANDTPTHPWQSAMTLARRVTLVETELGPVLRQRPVLPEVIPAGVMRVDVELSEGDALILESGFGEFSSRCVVHRGADGALVVDRSDADPHAVHTGFPATSPIPLPAGPVSGVLIEDHGLIELFLLDGLVTVALQTFPHPGPVRVRQLGADDRARATSSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGZ9</accession>
    <name>A0A1Q2CGZ9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ferredoxin-NADP reductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Stearoyl-CoA 9-desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_11765</name>
        <name evidence="8" type="ORF">SAMN05428934_106122</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11765"/>
    <dbReference type="EnsemblBacteria" id="AQP45391">
        <property type="protein sequence ID" value="AQP45391"/>
        <property type="gene ID" value="RPIT_11765"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93390">
        <property type="protein sequence ID" value="SDY93390"/>
        <property type="gene ID" value="SAMN05428934_106122"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11765"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="6">
        <location>
            <begin position="54"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="5">
        <location>
            <begin position="284"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY93390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="369" mass="38749" checksum="41963EFDAE82BDE4" modified="2017-04-12" version="1">MTASGLVAQPKGTSSLAKRALTGLGKGARRVAEAIATPLVPEDFLDLIDPLRSGADLRGRIVSVTPEGPGATTIVIRPGRGWRTHTPGQYTRIGFDINGVRLWRAYSITSRLGGDTISVTVRAIPDGKVSNAVRSLGPGTVVHLDQATGDFVLPQPPPPAALFLTAGSGITPIIGILRNSPLPADVVVVHSAPTVRDAMFLAELRALEAAGRIRLVTRFTATDGILTPDQLDDVVADWRDRHTWACGPAALLDDAEAHWALNGLSRLLHTERFRPTIVAVGDGGEVTFTTSGVVVEADAATTLLDAGEEAGVLMPSGCRMGICFNCVLPLTDGSVRDLRSGEVTTAIDQDPVRIQTCISAAAGPCRITI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH13</accession>
    <name>A0A1Q2CH13_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cation transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Divalent metal cation (Fe/Co/Zn/Cd) transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_11860</name>
        <name evidence="7" type="ORF">SAMN05428934_106102</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11860"/>
    <dbReference type="EnsemblBacteria" id="AQP45409">
        <property type="protein sequence ID" value="AQP45409"/>
        <property type="gene ID" value="RPIT_11860"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92927">
        <property type="protein sequence ID" value="SDY92927"/>
        <property type="gene ID" value="SAMN05428934_106102"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11860"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="127"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY92927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="317" mass="34553" checksum="ECA1DF94A0B7816B" modified="2017-04-12" version="1">MKTFGATTLPDEQREALHKAKRLEWISIAYTVVAVALIYAVMGSSQAMKAAWIEDMLAFLPPIAFLIAARAARHDPDHDNPYGKHRAVGAAHLAAAVALLAMGLFLVADSAMTLFTAEHPTIGTLNIFGYTVWQGWLMIGALIATGIPNVLLGRAKMKLAEPLHDKVLFADADMNKADWMTAFAAVVGVTGIGLGLWWLDSAVAILIGADIVKDGFSNLRGATGDLMDRQARTHDDKDEHPLVSEVRGVVDGLAWVAEAQVRMRDEGHVFHTEVFVVPHAEPTLELLESAQKVASSLDWKLDDLVIVPVRELPRREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH80</accession>
    <name>A0A1Q2CH80_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">ATP-binding cassette, subfamily B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_12175</name>
        <name evidence="11" type="ORF">SAMN05428934_10641</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY91573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12175"/>
    <dbReference type="EnsemblBacteria" id="AQP45467">
        <property type="protein sequence ID" value="AQP45467"/>
        <property type="gene ID" value="RPIT_12175"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY91573">
        <property type="protein sequence ID" value="SDY91573"/>
        <property type="gene ID" value="SAMN05428934_10641"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12175"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
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    <sequence length="262" mass="28360" checksum="8C452D169F381115" modified="2017-04-12" version="1">MSTTPVVDLRDVHVVHKSRTGKLFRPDRVHAVNGVNISVSKGETLGLVGESGCGKSTLARVMVGLQPVTSGEVRFKGEQMKLNAAGRKKLGRAVSVVFQDPATALNPRMIVRDTLLDPFKVHGVLEPSERENRVKELLDLVGLPQSALDVLPRQISGGQRQRVAIARALALDPDVIIADEPTSALDVSVRAQVLNLLSDLKDQLGLGLVFISHDINTVRYISDRMAVMLAGQIVETGQADQIFANPTHEYTRTLLSAVPSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHJ3</accession>
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            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY78092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12875"/>
    <dbReference type="EnsemblBacteria" id="AQP45589">
        <property type="protein sequence ID" value="AQP45589"/>
        <property type="gene ID" value="RPIT_12875"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY78092">
        <property type="protein sequence ID" value="SDY78092"/>
        <property type="gene ID" value="SAMN05428934_104112"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12875"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY78092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="137" mass="14571" checksum="E25A379B6A3C3FCA" modified="2017-04-12" version="1">MTDGFCFVAGQLAVDREFNIIGGDSLYEQTVAALGSCLTALESVGLGWAHVVRRTIYKLRPEGYFSDILPALQEVVPGQQPPQTLIGIPALAVPGTLIETARGLHTGRHDPRMIAAATVAPPPRMLNSLLVPLAASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHM0</accession>
    <name>A0A1Q2CHM0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_12710</name>
        <name evidence="12" type="ORF">SAMN05428934_104145</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY79006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12710"/>
    <dbReference type="EnsemblBacteria" id="AQP45560">
        <property type="protein sequence ID" value="AQP45560"/>
        <property type="gene ID" value="RPIT_12710"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY79006">
        <property type="protein sequence ID" value="SDY79006"/>
        <property type="gene ID" value="SAMN05428934_104145"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12710"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005543">
        <property type="entry name" value="PASTA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03793">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00740">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51178">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="347"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="12"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="PASTA" evidence="10">
        <location>
            <begin position="375"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="PASTA" evidence="10">
        <location>
            <begin position="442"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="PASTA" evidence="10">
        <location>
            <begin position="515"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="301"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="478"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="550"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="310"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="581"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP45560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY79006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="635" mass="67856" checksum="EF2C3E5FD2721F11" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHM2</accession>
    <name>A0A1Q2CHM2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4126 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45619">
        <property type="protein sequence ID" value="AQP45619"/>
        <property type="gene ID" value="RPIT_13045"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13045"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025196">
        <property type="entry name" value="DUF4126"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13548">
        <property type="entry name" value="DUF4126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4126" evidence="2">
        <location>
            <begin position="6"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="198" mass="20508" checksum="8C72A0E7F68E5BDA" modified="2017-04-12" version="1">MELLPMTFASGWASGINAYATVFILGLLGRFADTGGVPEGFQRTDVLIVMGILALIEVVADKVPVLDSIWDVPSTVIRPIAGALIGALIAGANGDLMTITLAAVGGVTALLSHLSKAGIRLAVNTSPEPVTNIGASVAGDVGVVGVTTLAVLFPVAAAVIAAILLAFMLWLAFKLGSRVRRGVRWMRQKFNQSAVDQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHP5</accession>
    <name>A0A1Q2CHP5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phytoene dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Phytoene desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_13195</name>
        <name evidence="6" type="ORF">SAMN05428934_10448</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1 3">Carotenoid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the carotenoid/retinoid oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY76336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13195"/>
    <dbReference type="EnsemblBacteria" id="AQP45646">
        <property type="protein sequence ID" value="AQP45646"/>
        <property type="gene ID" value="RPIT_13195"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY76336">
        <property type="protein sequence ID" value="SDY76336"/>
        <property type="gene ID" value="SAMN05428934_10448"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13195"/>
    <dbReference type="UniPathway" id="UPA00845"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014105">
        <property type="entry name" value="Carotenoid/retinoid_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02734">
        <property type="entry name" value="crtI_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="4">
        <location>
            <begin position="12"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY76336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="489" mass="52894" checksum="16DB63A2DBFB9C03" modified="2017-04-12" version="1">MSKHVVVVGAGLSGLAAAMHLAGAGHRVTVIEREAIPGGRSGVLERDGFRFDTGPVVFTMVSLLEEAFEAVGATWRDYVDMKLLDPAYHTFFADGSRLLVRPGHRKMRKEIAAMCGERDAVAFDKFVAWLTKLNDVELPHFIDANFNSPLSLFRSPVAALKLVALGGFGRLGRAVGRRFEDERLHRVFSFQAMYAGLAPAKALALYAVITYMDSIEGVWFPDGGMGAVPKAMAWAAAEAGVDFRWSTSVERVVRGADGAATGVRLTDGEIVTADAVVVTADLPVAYEKMLPELTPPRVARKGQYSPSAVVWHLGVRGEIPEDKGHHNIHFGEAWDDAFKDLLDRGVPMADPSRYVAIPSITDPTAAPEGCHTLYVLEPVPNLQVGKIDWAIEGPRLRERMLAFLEANGYPTDIVTEELVTPEDWLAQGMAAGTPFALSHKFSQTGPFRPKNIDKRVPGLVFAGSGTTPGVGIPMVLISGKLAAERVAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHX9</accession>
    <name>A0A1Q2CHX9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease P protein component</fullName>
            <shortName evidence="6">RNase P protein</shortName>
            <shortName evidence="6">RNaseP protein</shortName>
            <ecNumber evidence="6">3.1.26.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Protein C5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rnpA</name>
        <name evidence="8" type="ORF">RPIT_13595</name>
        <name evidence="9" type="ORF">SAMN05428934_11180</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.</text>
            <dbReference type="EC" id="3.1.26.5"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RnpA family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.5" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ13047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13595"/>
    <dbReference type="EnsemblBacteria" id="AQP45717">
        <property type="protein sequence ID" value="AQP45717"/>
        <property type="gene ID" value="RPIT_13595"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ13047">
        <property type="protein sequence ID" value="SDZ13047"/>
        <property type="gene ID" value="SAMN05428934_11180"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13595"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00227">
        <property type="entry name" value="RNase_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000100">
        <property type="entry name" value="RNase_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020539">
        <property type="entry name" value="RNase_P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33992">
        <property type="entry name" value="PTHR33992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00825">
        <property type="entry name" value="Ribonuclease_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00188">
        <property type="entry name" value="rnpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00648">
        <property type="entry name" value="RIBONUCLEASE_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ13047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="113" mass="12170" checksum="D808CA537FA2DC89" modified="2017-04-12" version="1">MLPGPRRLKRPADFGATVRQGARAATPSVVVHVLRSTITDPPGTTRVGFVVSKKVGGAVTRNRVKRRLRHLTLELPTPFTADAVVRALPEAASSPELPSHLADAWRRAHARAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CII3</accession>
    <name>A0A1Q2CII3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">High affinity sulphate transporter 1</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Sodium-independent anion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_14820</name>
        <name evidence="8" type="ORF">SAMN05428934_10956</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14820"/>
    <dbReference type="EnsemblBacteria" id="AQP45921">
        <property type="protein sequence ID" value="AQP45921"/>
        <property type="gene ID" value="RPIT_14820"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05653">
        <property type="protein sequence ID" value="SDZ05653"/>
        <property type="gene ID" value="SAMN05428934_10956"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14820"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="PTHR11814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="335"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="388"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="6">
        <location>
            <begin position="444"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ05653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="581" mass="61251" checksum="BA5661A5164AB6F1" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIK8</accession>
    <name>A0A1Q2CIK8_9ACTN</name>
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            <fullName evidence="5">Inorganic pyrophosphatase</fullName>
            <ecNumber evidence="5">3.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pyrophosphate phospho-hydrolase</fullName>
            <shortName evidence="5">PPase</shortName>
        </alternativeName>
    </protein>
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        <name evidence="5" type="primary">ppa</name>
        <name evidence="6" type="ORF">RPIT_01540</name>
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
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        <text evidence="5">Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>diphosphate + H2O = H(+) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:24576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01540"/>
    <dbReference type="EnsemblBacteria" id="AQP45959">
        <property type="protein sequence ID" value="AQP45959"/>
        <property type="gene ID" value="RPIT_01540"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01540"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF00719">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF50324"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
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        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>substrate</name>
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            <position position="39"/>
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        <ligand>
            <name>substrate</name>
        </ligand>
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        <ligand>
            <name>substrate</name>
        </ligand>
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            <position position="61"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
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    </feature>
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        <location>
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        <ligand>
            <name>Mg(2+)</name>
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            <label>3</label>
        </ligand>
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        </location>
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        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_00209"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP45959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="179" mass="19958" checksum="280789658268860F" modified="2017-04-12" version="1">MTPIDPGRRLLFDVTVEIPKGTKNKYEMDHNTGRIRLDRTLFTSTQYPYDYGFVEGTLGQDGDPLDAMVIGADPTFPGCLIECYAVAMFRMTDEMGGDDKVLCVATADTRRSHITDLSSVPEHMLLEIEHFFSVYKDLEPGKSVEGATWTGRDEAESEVAASFERAKGTPYEHIHTNLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIQ8</accession>
    <name>A0A1Q2CIQ8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04115"/>
    <dbReference type="EnsemblBacteria" id="AQP46009">
        <property type="protein sequence ID" value="AQP46009"/>
        <property type="gene ID" value="RPIT_04115"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04115"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd05829">
        <property type="entry name" value="Sortase_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023365">
        <property type="entry name" value="Sortase_dom-sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042001">
        <property type="entry name" value="Sortase_F"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="165" mass="18158" checksum="FA3C0AD28712F599" modified="2017-04-12" version="1">MAECTAVSDGFVPERYAIEAVGAKARVLSLGLDNEGNIAAPPKNESDTASWWNQGPRPGSDRGKAVLSIHTYRNGGAVGNDLYAGGTSQLKPGDLIKLYGPGGQVLCYEFAEAKKIWIDDYDPNSDVMVDFEGRHQLAIIICWDFDRRTEIWDSRIFFYGNPITP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIS9</accession>
    <name>A0A1Q2CIS9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_04470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04470"/>
    <dbReference type="EnsemblBacteria" id="AQP46017">
        <property type="protein sequence ID" value="AQP46017"/>
        <property type="gene ID" value="RPIT_04470"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04470"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000150">
        <property type="entry name" value="Cof"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00099">
        <property type="entry name" value="Cof-subfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP46017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="262" mass="28656" checksum="76E97E09ADA0D6C0" modified="2017-04-12" version="1">MVAVIAVDMDGTFLRPDDTYDRARFERLRERMRAQGVRFVVASGNQLHQLRSFFAEADGCAYVAENGHIVVDEGSTAPLSRSVLAADASLRVINALDAVGFPYVMSGTECAFVRADAPPHFVDLVRRYYHRLEVVSDLRDLDVEVMKFAMITDVDPDEVATRIEGEVGDVMSVVVSGPRDLDLNQPGVTKAFGLGLLLDRWGVSWDDVVAFGDGGNDVELLQAAGRGYAMEGARDELVAVASHRTGRNTDDAVLTLIEEILH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIT4</accession>
    <name>A0A1Q2CIT4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydropteroate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01575"/>
    <dbReference type="EnsemblBacteria" id="AQP45960">
        <property type="protein sequence ID" value="AQP45960"/>
        <property type="gene ID" value="RPIT_01575"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01575"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004156">
        <property type="term" value="F:dihydropteroate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009396">
        <property type="term" value="P:folic acid-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00739">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="PTHR20941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01496">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00793">
        <property type="entry name" value="DHPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pterin-binding" evidence="1">
        <location>
            <begin position="1"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="261" mass="27697" checksum="81681D1A8E627C28" modified="2017-04-12" version="1">MGILNVTPDSFSDGGDFLDPDAALVHAREMLAAGASIIDVGGESTRPGAQRVSESDEMRRVVPIVRALAADGVTVSVDTMRAAVAAAALEAGAQLINDVSGGLADRDMLSVVAASSADFVVMHWRDHSERMQREAVYGDVVAEVTQELLNRRDAAVEAGVDATRLILDPGLGFAKTWDHNWTLLRNLDHFQALGHRLLVGASRKAFLGELLGGREPQGRDSATAAISFWAAQHGVWGVRTHEVSGQVDAVAVARRLTDGQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIX7</accession>
    <name>A0A1Q2CIX7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nuclease-related domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_07165</name>
        <name evidence="4" type="ORF">SAMN05428934_11011</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP46067">
        <property type="protein sequence ID" value="AQP46067"/>
        <property type="gene ID" value="RPIT_07165"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08195">
        <property type="protein sequence ID" value="SDZ08195"/>
        <property type="gene ID" value="SAMN05428934_11011"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07165"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011528">
        <property type="entry name" value="NERD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08378">
        <property type="entry name" value="NERD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50965">
        <property type="entry name" value="NERD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NERD" evidence="2">
        <location>
            <begin position="131"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ08195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="301" mass="32792" checksum="4AB494F950BDD053" modified="2017-04-12" version="1">MRLRYAGTCAACGVPLAAGTTADYDRTSKTVACIVCPPTDANTDQGERRDPSIDVGSPTVTEDAPAVEASPEVWERPTLEAVDGQGGASAAAEFQRRHGARRDRVLNSYPRMGKFLLAVFDDPQSTKAWSVGAEGERLLSEMLAGMAGESLRVLNDRRIPRTRANIDHLVVCPSGVFVVDAKRYRNARPALKVEGGLIRPRTELLTVAGRDRTTLVTGMQKQLDLVQTALADQPDIPVWGVLCFVEADWPLLGGPFTVNGVHVMSPKKLRAQLTHPGPLDEARIADVQWHLHEAFPRQKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIZ4</accession>
    <name>A0A1Q2CIZ4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamate-1-semialdehyde 2,1-aminomutase</fullName>
            <shortName evidence="7">GSA</shortName>
            <ecNumber evidence="7">5.4.3.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamate-1-semialdehyde aminotransferase</fullName>
            <shortName evidence="7">GSA-AT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hemL</name>
        <name evidence="9" type="ORF">RPIT_04740</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(S)-4-amino-5-oxopentanoate = 5-aminolevulinate</text>
            <dbReference type="Rhea" id="RHEA:14265"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="5.4.3.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.3.8" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04740"/>
    <dbReference type="EnsemblBacteria" id="AQP46020">
        <property type="protein sequence ID" value="AQP46020"/>
        <property type="gene ID" value="RPIT_04740"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04740"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00317"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042286">
        <property type="term" value="F:glutamate-1-semialdehyde 2,1-aminomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00375">
        <property type="entry name" value="HemL_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004639">
        <property type="entry name" value="4pyrrol_synth_GluAld_NH2Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00713">
        <property type="entry name" value="hemL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="4 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP46020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="428" mass="43909" checksum="280C4840BB0AA2D6" modified="2017-04-12" version="1">MNADQDLFERARKVIPGGVSSPVRAFGSVGGAPVFVSRASGPYIVGADGVEYVDLVCSWGPALLGHAHPEVVEAVRGAAGRGLSFGAPTEAEVELAEAIRSRVPAAELVRFVSTGTEATMTAVRLARGATGRDIIVKFAGCYHGHSDALLAAAGSGVATQGLPGSAGVTAAAAADTIVVGYNDPTALDAVFERMGDRIAAVITEAAPANMGVVPPSAGFNALIRELTARHGALMILDEVLTGFRVGPAGWLGLEGGYRPDLITFGKVVGGGMPLAALGGRADLLGMLAPLGPVYQAGTLSGNPLATAAGLATLRLADDAVYEHVNRRSAELQSAVGEALSRAGVPHVVQNAGNLFSVFFRAEPVRTYDDAKDQDTAAFARFFHSMLDSGIALPPSAFEAWFLSAAHDDRAMARITDALPQAARAAADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ04</accession>
    <name>A0A1Q2CJ04_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05165"/>
    <dbReference type="EnsemblBacteria" id="AQP46030">
        <property type="protein sequence ID" value="AQP46030"/>
        <property type="gene ID" value="RPIT_05165"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05165"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF58" evidence="1">
        <location>
            <begin position="49"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="330" mass="37215" checksum="66C1BC592F7C2946" modified="2017-04-12" version="1">MLRPPSGPTIPLNRLAPEAALRRLELTIVRRLEGFLHGDHLGLLPGAGSDTNDARVYQPGQDDVRKMDWAVTARTTVPHVRDTMADRELEIWALLDVTPSMNWGTEGVTKRDLGIAAIATIGFLSQKMGDRFGGMMMLPDQVKRLPARSGRTALYGLLRKMLTEPIVPDHAEGDLQLEDGIEQMTRSQRRRGMRVIVSDFLTPGDAELDPNVPPAWERAVRRLAVRNQVLCVEVVDRHEVEFPDVGEMLIRDPETDFSRYINTSDDAARRRMDAATRAQRERIKVALRRAGAGHIQLRTDRDWVADIARFVLNYRRVANMLHQPPQGVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJG0</accession>
    <name>A0A1Q2CJG0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA_binding_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP46175">
        <property type="protein sequence ID" value="AQP46175"/>
        <property type="gene ID" value="RPIT_13715"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13715"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="SSF46767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_binding_1" evidence="1">
        <location>
            <begin position="21"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="123" mass="13754" checksum="C498A038ED653034" modified="2017-04-12" version="1">MFDDDWVLQPSGPTEAELTVERVLRAVEQVPRGRVVAYSDIATVVGTSPRRVGSIMAGHGGEVAWWRVTNRDGALPAHLLELAKKHWQREGIEADETRCRINRHRADLDDLALGYQKAVRDLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBE5</accession>
    <name>A0A1Q2CBE5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00155</name>
        <name evidence="2" type="ORF">SAMN05428934_10913</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ04758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_040284067.1">
        <property type="nucleotide sequence ID" value="NZ_FNPU01000009.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43429">
        <property type="protein sequence ID" value="AQP43429"/>
        <property type="gene ID" value="RPIT_00155"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ04758">
        <property type="protein sequence ID" value="SDZ04758"/>
        <property type="gene ID" value="SAMN05428934_10913"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00155"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ04758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="75" mass="8407" checksum="A3168B32B65409B0" modified="2017-04-12" version="1">MEDPVIAPSALKHGLGEHEILHAYRNPVRIWDLGDGFTMIVGPNQSAIFLEVGYVDGDQVHVIVHAMKAREKFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBH8</accession>
    <name>A0A1Q2CBH8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Leucyl/phenylalanyl-tRNA--protein transferase</fullName>
            <ecNumber evidence="4">2.3.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">L/F-transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Leucyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Phenyalanyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">aat</name>
        <name evidence="6" type="ORF">RPIT_00380</name>
        <name evidence="7" type="ORF">SAMN05428934_10530</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = H(+) + N-terminal L-leucyl-L-arginyl-[protein] + tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:50416"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12672"/>
            <dbReference type="Rhea" id="RHEA-COMP:12673"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64719"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:133044"/>
            <dbReference type="EC" id="2.3.2.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = H(+) + N-terminal L-leucyl-L-lysyl-[protein] + tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:12340"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12670"/>
            <dbReference type="Rhea" id="RHEA-COMP:12671"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:65249"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:133043"/>
            <dbReference type="EC" id="2.3.2.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an N-terminal L-alpha-aminoacyl-[protein] + L-phenylalanyl-tRNA(Phe) = an N-terminal L-phenylalanyl-L-alpha-aminoacyl-[protein] + tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:43632"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="Rhea" id="RHEA-COMP:10636"/>
            <dbReference type="Rhea" id="RHEA-COMP:10637"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:83561"/>
            <dbReference type="EC" id="2.3.2.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the L/F-transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.6" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY84208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00380"/>
    <dbReference type="EnsemblBacteria" id="AQP43460">
        <property type="protein sequence ID" value="AQP43460"/>
        <property type="gene ID" value="RPIT_00380"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY84208">
        <property type="protein sequence ID" value="SDY84208"/>
        <property type="gene ID" value="SAMN05428934_10530"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00380"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008914">
        <property type="term" value="F:leucyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00688">
        <property type="entry name" value="Leu_Phe_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004616">
        <property type="entry name" value="Leu/Phe-tRNA_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042203">
        <property type="entry name" value="Leu/Phe-tRNA_Trfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042221">
        <property type="entry name" value="Leu/Phe-tRNA_Trfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30098">
        <property type="entry name" value="PTHR30098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03588">
        <property type="entry name" value="Leu_Phe_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00667">
        <property type="entry name" value="aat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY84208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="242" mass="26435" checksum="AAB0A837C5CCCEE6" modified="2017-04-12" version="1">MLGVTFGLPSEWPSQDLIGYTDEFSAALALEGYRCGVFPMPINAGDSEMGWWSPMQRGLLPVDGLHVTRSMRRAAKRYTTTVDAAFDDVVAACADPDRPHGWIDTRIRTAYARLHATGWAHSVETWDRDGRLVGGLYGVHVGGLFAGESMFHDPELGRDASKVALMRLVEELTAAGVILVDVQWLTDHLGSLGAYEVPRRVYLSRLNVALGLPQSPWPGALTVPGRRVGPPNSHPPPRPEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBL4</accession>
    <name>A0A1Q2CBL4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glucose-6-phosphate isomerase</fullName>
            <shortName evidence="7">GPI</shortName>
            <ecNumber evidence="7">5.3.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Phosphoglucose isomerase</fullName>
            <shortName evidence="7">PGI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphohexose isomerase</fullName>
            <shortName evidence="7">PHI</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pgi</name>
        <name evidence="9" type="ORF">RPIT_00620</name>
        <name evidence="10" type="ORF">SAMN05428934_10577</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7 8">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7 8">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the GPI family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY85466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00620"/>
    <dbReference type="EnsemblBacteria" id="AQP43503">
        <property type="protein sequence ID" value="AQP43503"/>
        <property type="gene ID" value="RPIT_00620"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY85466">
        <property type="protein sequence ID" value="SDY85466"/>
        <property type="gene ID" value="SAMN05428934_10577"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00620"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00181"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023096">
        <property type="entry name" value="G6P_Isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="PTHR11469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P_GLUCOSE_ISOMERASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00174">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="4 7 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
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        <location>
            <position position="366"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="397"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP43503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY85466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="557" mass="60981" checksum="FBE3CC678C1764F4" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBL9</accession>
    <name>A0A1Q2CBL9_9ACTN</name>
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        <submittedName>
            <fullName evidence="5">Glycosyltransferase involved in cell wall bisynthesis</fullName>
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    </protein>
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        <name evidence="5" type="ORF">SAMN05428934_10575</name>
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        <name type="scientific">Tessaracoccus flavus</name>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00610"/>
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        <property type="gene ID" value="RPIT_00610"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY85410"/>
        <property type="gene ID" value="SAMN05428934_10575"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <location>
            <begin position="21"/>
            <end position="259"/>
        </location>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY85410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="490" mass="53986" checksum="5FAE9889B757094E" modified="2017-04-12" version="1">MTVKAPRIVLFRHAPVDFDSRIKRVARTLQRGGFEPIIISVEPADGESGEFLLGGDIRVIRVPLKVAPAAPKPAAQVAADADKLRRQRKVYAQRVSGLDARSAKSAIKWGLTSGRLASMRGNRFAKALLRRANSAKVALVERNHPFNSLDLAANHPQAYNITHTLTDLLVSLEPDVLHAHNPVALPAAYEAMVRLKARGKTVKLSYDVREDFAGLPDKEIGSRNAFDAVLEMEKRFMPFADYVWTVTESHAELLKKKYNLPVLPDTFVNMSVFQPMVGDITVREAAGLSEDTPLLVYAGIMSWARGMETLIEAMSMVDEAVHLAIVSVPNPHPMKPKLEALAEEFGVLDRIHFVDPVSQAHLSYYLSGADIAVHPLPGGSPNHDRTLPNKLFEYMHAELPLVSSDAKTMAKFVVDNGMGEVFRSEDPVDLARAISLELRNPVSQEHMHALAEKFSWQANEPRIIEAYSRLTGFPGTLADGEFGTTEVTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBQ0</accession>
    <name>A0A1Q2CBQ0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00785</name>
        <name evidence="2" type="ORF">SAMN05428934_105110</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43532">
        <property type="protein sequence ID" value="AQP43532"/>
        <property type="gene ID" value="RPIT_00785"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86351">
        <property type="protein sequence ID" value="SDY86351"/>
        <property type="gene ID" value="SAMN05428934_105110"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00785"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015068">
        <property type="entry name" value="DUF1877"/>
    </dbReference>
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        <property type="entry name" value="YfbM-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08974">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111069">
        <property type="entry name" value="SSF111069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY86351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="149" mass="16259" checksum="13CDDB861905837A" modified="2017-04-12" version="1">MGMLATFTPIPAGCVDDVVEDPSLIERDYADVAVDCDKAWQGIHFLLTGSDWEGDPPLSLMIMGGRELTDDGVRLLSSDEVQQVAATLPMEEVLRARFDPQRMNQLDIYPGIWSEGDAACDYLLEHYGPLADLFRDAAGRGDAIAISIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBQ7</accession>
    <name>A0A1Q2CBQ7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00815</name>
        <name evidence="4" type="ORF">SAMN05428934_105116</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00815"/>
    <dbReference type="EnsemblBacteria" id="AQP43538">
        <property type="protein sequence ID" value="AQP43538"/>
        <property type="gene ID" value="RPIT_00815"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86500">
        <property type="protein sequence ID" value="SDY86500"/>
        <property type="gene ID" value="SAMN05428934_105116"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00815"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00359">
        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY86500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="406" mass="45252" checksum="B245800516FE50A4" modified="2017-04-12" version="1">MSEGACRRISVKPGEATSPRVESFDGVWRVRSTEAVRQILRQRDATAQAGFNSESIPDGTMADQPILFMDGEPHRQQRSKIARYFAPKTVAARYRELMERRADALVAEMVADGRARLDDVSLRYSTEVAAKVIGLTNSRTDRMARRLEKLFDQPPYDPARGDGEGRVRAALRQLRGAAPMAWFYVWDVRPAIRERRREPQEDVISHLLKEGYGIPAILIECVTYGAAGMATTREFISMAALHLLRDDALRARYVQADEPERYAILHEILRLEPIVGHLYRRAEREFTFDDAGATHTVRAGQLLDLHIRQANADPTTVGDAPLDLCPGRELPRGIGAEVMSFGDGPHKCPGNALAIQETDILLTRLFAHDVALVGEPDLGWDEIISGYALRNVTIAVSPSDLHRLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBS2</accession>
    <name>A0A1Q2CBS2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43551">
        <property type="protein sequence ID" value="AQP43551"/>
        <property type="gene ID" value="RPIT_00880"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00880"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025645">
        <property type="entry name" value="DUF4349"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14257">
        <property type="entry name" value="DUF4349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="266" mass="28993" checksum="9D12737D83B17EF4" modified="2017-04-12" version="1">MPEQGGDEAGDGDRMIIRAKVLRLEVESTPDAVTQVREIAREYDGSVTDMQVATDSEEWLYRYEKDGTIVGDGAALRGWVTVRVPSETYEEFVDDVAGVGVVKFQSEATSDVTQEHVDLSARLENLRAQEARLREFFDEARTVKDMLAIETELSRVRGEIESMDAQVTYLERQAAMATVTIELTEPRAVVRPGGESWGFVDAITNGIRGAAGLLTGTITVLIATAPVWLTALVLFFPIRAFLRRRAERGAAGSGDSVDPGSVPPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBV3</accession>
    <name>A0A1Q2CBV3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-2 type transport system ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Multidrug ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_01050</name>
        <name evidence="6" type="ORF">SAMN05428934_105161</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43580">
        <property type="protein sequence ID" value="AQP43580"/>
        <property type="gene ID" value="RPIT_01050"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87730">
        <property type="protein sequence ID" value="SDY87730"/>
        <property type="gene ID" value="SAMN05428934_105161"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01050"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY87730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="309" mass="32460" checksum="62FB256DBB84BA8E" modified="2017-04-12" version="1">MIRVQNLTKRYGKRLAVDGVSFTVEPGRVTGFLGPNGAGKSTTMRMIVGLARPTTGSATLNGREYRHLPGPLRDVGALLDARSAHRGRTAYKHLLSLAATHGIGKARVHEVIGLAGLESVAHRRVGGFSLGMGQRLGIAAALLGDPRIVILDEPVNGLDPEGIIWIRSLLRGLAEDGRTVLLSSHLMSEMTQTADHLIVIGRGRILADGPLHDVVSQATGDAVRVRTPDVQALIQAVDRRATTITLTPDGALEISGLSPAQVAEAAGSAGVVLHELTPLRGSLEAAYLSLTAEAVEYRANTAEANGTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBZ5</accession>
    <name>A0A1Q2CBZ5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF262 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00960</name>
        <name evidence="3" type="ORF">SAMN05428934_105143</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00960"/>
    <dbReference type="EnsemblBacteria" id="AQP43565">
        <property type="protein sequence ID" value="AQP43565"/>
        <property type="gene ID" value="RPIT_00960"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87230">
        <property type="protein sequence ID" value="SDY87230"/>
        <property type="gene ID" value="SAMN05428934_105143"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00960"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="DUF262"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="DUF262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="4"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY87230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="647" mass="72108" checksum="CD6124E9AB905E56" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC74</accession>
    <name>A0A1Q2CC74_9ACTN</name>
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    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43697">
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        <property type="gene ID" value="RPIT_01795"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01795"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="250" mass="26647" checksum="98356B0A553DA294" modified="2017-04-12" version="1">MVQRVPDEYFRKRAAESEDIDESADERHRPPSTTARAVVARDAQGGLPPRATAIVVVLALALSFLAGRLFLFPPVVVPPTPSSSASTSMGPDPSTDAFSAYEGPVSAVQPIAALGECREGGTLESPSALLDGDPETLWRCRGAGDGESFTIVFDGPVSLAGIRIVNGNVAWPDRYAVERRITAVRWTFADGSYFEQGLAANDRNAQEVRFPETLTDRATLEVLSATVPGEISPNSDAVSISSLEFLTPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC77</accession>
    <name>A0A1Q2CC77_9ACTN</name>
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        <submittedName>
            <fullName evidence="5">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
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        <name evidence="4" type="ORF">RPIT_01920</name>
        <name evidence="5" type="ORF">SAMN05428934_11620</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000016">
        <property type="protein sequence ID" value="SDZ20488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01920"/>
    <dbReference type="EnsemblBacteria" id="AQP43718">
        <property type="protein sequence ID" value="AQP43718"/>
        <property type="gene ID" value="RPIT_01920"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ20488">
        <property type="protein sequence ID" value="SDZ20488"/>
        <property type="gene ID" value="SAMN05428934_11620"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01920"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045823">
        <property type="entry name" value="TetR_C_32"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19344">
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    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="24"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
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            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ20488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="211" mass="23747" checksum="84E340F3EA3BAC52" modified="2017-04-12" version="1">MNQKSGATAPVQDGRASRWEEHNNQRRRALVQDAVRAIRKHGPHVGMDEIAAQAKTSKTVLYRHFGDKAGLYRAVVESVQDFIVRKLPLDEADNLPPHELILRLADAYLAVVERDRNLYLFVSSRPTSDSPDPVTGVTTRIGNEVATVLRAWLRREGLDEEPANIWGHGAVGFIWAVSDRWIITNFRRPRAEVVGYVDQLFAPAFAAQQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCC5</accession>
    <name>A0A1Q2CCC5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_02190</name>
        <name evidence="4" type="ORF">SAMN05428934_10137</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY23419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02190"/>
    <dbReference type="EnsemblBacteria" id="AQP43768">
        <property type="protein sequence ID" value="AQP43768"/>
        <property type="gene ID" value="RPIT_02190"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY23419">
        <property type="protein sequence ID" value="SDY23419"/>
        <property type="gene ID" value="SAMN05428934_10137"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02190"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
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            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY23419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="504" mass="49824" checksum="AC956152E4C0BCE9" modified="2017-04-12" version="1">MWEQIGELFGDLAAAGGQIVVDAWVAICIAVWGAGLWVMRAILQLGDWFLTPNLNPDGSSSALWSVYGVTLWLGLSLALMLLIVQLVGTVLRRDALSLASAVWGSVKFLLVCTLWYTYGAALVTAVEGLNTALRLQLLGTADLADWEPTGLDFTEGVMTGTTATVLMLLGLVLWLAALAHLVVMLGRAVSLIVIAATAPIAAAGLMFKPFESWFWKAFRWFHAAAIAPLLMTLMLGLGVRLATGVSLGMEDSGQEAVALALPSVVMIAVAALSPVALFRLLAFVDPGTTSGASFRAGLAGTTGASSAASYAHTAMTRSSGSGSGGGGVAGAGESATASRTAAAQSSSLSPGAAGGAAASGGAGGSAAGVGGAAAGGTSAGGAAAGGAAAGGGAATGAAAGVGAVAGPVGVVAAGVILGAKKLVDGFQQVGARATGLVNDTTSGMGAGDPSYPYDPAGDIRRTPHPAQPHPAQVATQTTSTQPQRAAQPPVAVREAEDHNGGQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCD1</accession>
    <name>A0A1Q2CCD1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nitrate reductase (quinone)</fullName>
            <ecNumber evidence="5">1.7.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">RPIT_02130</name>
        <name evidence="14" type="ORF">SAMN05428934_10124</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinol + nitrate = a quinone + H2O + nitrite</text>
            <dbReference type="Rhea" id="RHEA:56144"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16301"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.7.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.7.5.1" evidence="5"/>
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        <property type="protein sequence ID" value="AQP43757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY23014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02130"/>
    <dbReference type="EnsemblBacteria" id="AQP43757">
        <property type="protein sequence ID" value="AQP43757"/>
        <property type="gene ID" value="RPIT_02130"/>
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    <dbReference type="EnsemblBacteria" id="SDY23014">
        <property type="protein sequence ID" value="SDY23014"/>
        <property type="gene ID" value="SAMN05428934_10124"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02130"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009325">
        <property type="term" value="C:nitrate reductase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008940">
        <property type="term" value="F:nitrate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042126">
        <property type="term" value="P:nitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02776">
        <property type="entry name" value="MopB_CT_Nitrate-R-NarG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037943">
        <property type="entry name" value="MopB_CT_Nitrate-R-NarG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027467">
        <property type="entry name" value="MopterinOxRdtase_cofactor_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006468">
        <property type="entry name" value="NarG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="narG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00551">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0408">Iron</keyword>
    <keyword evidence="9 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="12">
        <location>
            <begin position="54"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="857"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00010312"/>
        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00012500"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP43757.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY23014.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
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    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="1235" mass="137331" checksum="F8ECFBF6135CFCAF" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCD9</accession>
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        <lineage>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
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            <dbReference type="PubMed" id="26869509"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
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        <source>
            <dbReference type="EMBL" id="AQP43779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="62" mass="6992" checksum="BAF5F22713C3BC3A" modified="2017-04-12" version="1">MALHLVTDGLCHRVQTVQFIDTQLTHREILFEQMLHVQGGAPDQGLKEGLTFGQSFGLWGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCH9</accession>
    <name>A0A1Q2CCH9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family</fullName>
        </submittedName>
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    <gene>
        <name evidence="4" type="ORF">RPIT_02480</name>
        <name evidence="5" type="ORF">SAMN05428934_10194</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 6">RP1T</strain>
        </source>
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    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="SDY25061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="RPIT_02480"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY25061">
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        <property type="gene ID" value="SAMN05428934_10194"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SH3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00287">
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
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        <location>
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            <end position="459"/>
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        </location>
    </feature>
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            <begin position="324"/>
            <end position="346"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43822.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY25061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="459" mass="48650" checksum="DDDD38979B7DAD9F" modified="2017-04-12" version="1">MKTALRSLRGLAVATAAAILIQGLGSIALGPAADARDGDVTATARVHVRSGPSTSSQSLTVLDKGDVLPALGSEGSWTKVTFEGRTAYVFSAYLTGASSAPSSETSNGTSTGTAGTVATTANLNLRVGPSIRDRVSVVAPTGTRLTLTGSVSGEYAQVTYAGQTLWASTRYLSDPAANSGSTPQVVGKGRALANLLIRTSSDTAYSVITTVPRDTILEMTGVQANGMTQVVFRGVARWVNGSYFAPFGGAAVAPQPQPPATPETSDRYATTVLNIWTASTGTAYIRDIPRGTVVKVTGVVENGRAAIVDDGAIRWVTARYLSTTPPSSGASGGADDSLNRGGSSGLDKTNDNVKAIALDIWERYPQITTMYGWRRDVTPDHPAGRAVDVMIPSYGRNQALGWEIANYYRDNAEQYNINYIIFAQRIWSVARDKEGWRWMANRGSDNANHYNHVHINTYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCL9</accession>
    <name>A0A1Q2CCL9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-amylase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Amylosucrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02530</name>
        <name evidence="3" type="ORF">SAMN05428934_101106</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY25432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02530"/>
    <dbReference type="EnsemblBacteria" id="AQP43830">
        <property type="protein sequence ID" value="AQP43830"/>
        <property type="gene ID" value="RPIT_02530"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY25432">
        <property type="protein sequence ID" value="SDY25432"/>
        <property type="gene ID" value="SAMN05428934_101106"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02530"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047669">
        <property type="term" value="F:amylosucrase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11324">
        <property type="entry name" value="AmyAc_Amylosucrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044077">
        <property type="entry name" value="Amylosucrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="1">
        <location>
            <begin position="73"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY25432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="618" mass="69510" checksum="607E20E144543063" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCM0</accession>
    <name>A0A1Q2CCM0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isochorismate synthase</fullName>
            <ecNumber evidence="3">5.4.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_02620</name>
        <name evidence="7" type="ORF">SAMN05428934_101124</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>chorismate = isochorismate</text>
            <dbReference type="Rhea" id="RHEA:18985"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29780"/>
            <dbReference type="EC" id="5.4.4.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the isochorismate synthase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.4.2" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY26004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02620"/>
    <dbReference type="EnsemblBacteria" id="AQP43846">
        <property type="protein sequence ID" value="AQP43846"/>
        <property type="gene ID" value="RPIT_02620"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY26004">
        <property type="protein sequence ID" value="SDY26004"/>
        <property type="gene ID" value="SAMN05428934_101124"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02620"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008909">
        <property type="term" value="F:isochorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004561">
        <property type="entry name" value="IsoChor_synthase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00543">
        <property type="entry name" value="isochor_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate_bind" evidence="5">
        <location>
            <begin position="146"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY26004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="407" mass="43388" checksum="FC1956A57753B72B" modified="2017-04-12" version="1">MRATTVAVDDPGPLERFLPEAGLSSAFIRRGEGFITLGEVARFETDRAEAADVWWDEISAQIDHDSEMPGEFGTGPIAVGSFTFDPDRSEERSVLTVPELILGRRGGVSWLTRLGTNHTDCSLPPRGEPVRAPSGLEVLGGSMGEDVWTDIVAEVVSLIRRDEVHKVVLARDLRVRADQPFDLRFLLGRLIDSYPTTWAYLVDGLVGATPELLLRRQGGLVTSRVLAGTVSHDADADPLARAAELARSSKDIGEHEFAVESVAQALAPFCQAMNVPEAPSVLKLPNVMHLATDITGVAKPENSALALAAALHPSAAVCGTPTHLALDIIAELESLDRSRYAGPVGWVDTEGDGEWAIALRGGQVRPQCPDEIQLFAGAGIVADSSPDAELAETGAKFVPMLQALGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCR7</accession>
    <name>A0A1Q2CCR7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplJ</name>
        <name evidence="7" type="ORF">RPIT_02905</name>
        <name evidence="8" type="ORF">SAMN05428934_101182</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY27675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02905"/>
    <dbReference type="EnsemblBacteria" id="AQP43891">
        <property type="protein sequence ID" value="AQP43891"/>
        <property type="gene ID" value="RPIT_02905"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY27675">
        <property type="protein sequence ID" value="SDY27675"/>
        <property type="gene ID" value="SAMN05428934_101182"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02905"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05797">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00362">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022973">
        <property type="entry name" value="Ribosomal_L10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_L10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_L10P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11560">
        <property type="entry name" value="PTHR11560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="SSF160369"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="177"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY27675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="205" mass="20599" checksum="9A138C44AC11E03D" modified="2017-04-12" version="1">MARPDKAAKVAELADQFSNSAAAVLTEYRGLTVKDLKELRRSLGENASYAVAKNTLTAIAAKEAGIEGIEDTLTGPTAIAFVSGDIAAATKGLRDFAKAHPSLAIKGGVLEGKFLDAQAVLKLADLESREVLLAKMAGAMQANLAKAAYLLAAPLSQGARALGALATAAEANPSLIGGAGSAPATEATDETPAADAAPEAAEAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCY7</accession>
    <name>A0A1Q2CCY7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Myo-inositol catabolism protein IolH</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Protein iolH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03305</name>
        <name evidence="3" type="ORF">SAMN05428934_101262</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03305"/>
    <dbReference type="EnsemblBacteria" id="AQP43961">
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        <property type="gene ID" value="RPIT_03305"/>
    </dbReference>
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        <property type="gene ID" value="SAMN05428934_101262"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="22"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY30177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="287" mass="33344" checksum="3F2E3327D262DCB1" modified="2017-04-12" version="1">MVKILLDPSMYHPHLTVAEECQKAADLGYEYIELSPRADFHEWHHYPKVDDAEIAKVKKAMASTGVKIWSLNPVYNWASPDEEERQHQVRNFRRTLEIAQELEIPLIATEYSGDPNQPVRSENQFYKSIEELIPEFESRGLECAVEAHPYDFVETNDRAVQVVRGVNKPWFNYQFCLPHMFHLSSGSYDARSMMEYAGERLKHLHIADGFNHLANVGNRYIINPPGVDARIHQHNEIGNGEVPWGEVFDYLREINYDGALSVCVFGWEEEADAIHIRMRERLEAEFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD09</accession>
    <name>A0A1Q2CD09_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative drug exporter of the RND superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_03535</name>
        <name evidence="10" type="ORF">SAMN05428934_101308</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY31569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43999">
        <property type="protein sequence ID" value="AQP43999"/>
        <property type="gene ID" value="RPIT_03535"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY31569">
        <property type="protein sequence ID" value="SDY31569"/>
        <property type="gene ID" value="SAMN05428934_101308"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03535"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="536"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="560"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="596"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="634"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="660"/>
            <end position="681"/>
        </location>
    </feature>
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        <location>
            <begin position="563"/>
            <end position="691"/>
        </location>
    </feature>
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        <location>
            <begin position="448"/>
            <end position="479"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP43999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY31569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="725" mass="75912" checksum="E37346AF39694326" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD10</accession>
    <name>A0A1Q2CD10_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutamine synthetase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_03500</name>
        <name evidence="6" type="ORF">SAMN05428934_101300</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the glutamine synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY31350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03500"/>
    <dbReference type="EnsemblBacteria" id="AQP43994">
        <property type="protein sequence ID" value="AQP43994"/>
        <property type="gene ID" value="RPIT_03500"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY31350">
        <property type="protein sequence ID" value="SDY31350"/>
        <property type="gene ID" value="SAMN05428934_101300"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03500"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
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        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03951">
        <property type="entry name" value="Gln-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="4">
        <location>
            <begin position="104"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY31350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="441" mass="49989" checksum="704EDA93CD597EBE" modified="2017-04-12" version="1">MDRQTEFVLRSMEERGIRFVRLWFTDVLGSLKSVAIAPAEVEGAIAEGVGFDGSAIEGFARVFESDMVAHPDPSTYQVLPWREGGRSTARMLCDIRLPDGSPSFADPRYVLKRALDGAGRKGFTFYIHPEIEFFLLRTLNPPTPLDEGGYFDHTTLGDGTDFRRDAITMLEQMGISVEFSHHEAAPGQHEIDLRYADALTMADNVMTFRVVIREVAVSQGIHASFMPKPFSEHPGSGMHTHMSLFEGDTNAFYDAADEYHLSKTAKQFIAGLLRHAPEITAVTNQWVNSYKRLVGGDEAPSYACWGRSNRSALIRIPQFTPGKTSSARIEYRAVDAAVNPYLAYALMLNAGLKGIEEEYQLPEETEDEVWRLTDRERQAIGIRELPRNLDQALRLMEESEVVAETLGEHVFEYFLRNKREEFAVYRRQVTPWELERHIRVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD33</accession>
    <name>A0A1Q2CD33_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_03580</name>
        <name evidence="9" type="ORF">SAMN05428934_101317</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
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    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
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</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="1610493.RPIT_03680"/>
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    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY32474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
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        <recommendedName>
            <fullName evidence="2">DsbD domain-containing protein</fullName>
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    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_03850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Cyt_c_assmbl_TM_dom"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="6"/>
            <end position="34"/>
        </location>
    </feature>
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        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        </location>
    </feature>
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            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
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        <location>
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            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
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        <location>
            <begin position="9"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="269" mass="26826" checksum="F9C1519080779650" modified="2017-04-12" version="1">MMGVGYAGAFLGGAAALFSPCAALLLPAFFAYAFGGSKATLLGRTALFYLGLLLTLVPLGVAAGALGGLLTTHRGTVATIGGVVLIGFGLLTALGIQLPVPGVKQSGRDPRGALGTVLLGATYGLAGACTGPLLGAVLTMAAVGGSVGYGAVLLALFGAGMVVPLVLLALVWDRLRLGQRWGRARALRIGPFTTSVLGLVSGLLFAAVGVLFVATDATAGLGGILDATAQFRLESWLAEVGRAVPDLAVMGAAAVVVLLVGWGWLRGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDA2</accession>
    <name>A0A1Q2CDA2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03970"/>
    <dbReference type="EnsemblBacteria" id="AQP44076">
        <property type="protein sequence ID" value="AQP44076"/>
        <property type="gene ID" value="RPIT_03970"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03970"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF58" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="199" mass="21270" checksum="9439F2013178D378" modified="2017-04-12" version="1">MRRVHWKLSAKQDDLMVRLEEHPWDPSSTLIVDTRTAAHFGDGPRGSLEWAVSAVASVAALLTEGRHRVAILSPSGVVHQSGRAVGESAKRAMIESLTDLTASDIDWLGEAVADPEAMGSSAAVIAVTGLLKPSDAAALVAASARARKLIALVPDADAWGGAPHPEHDKACRLLLGHGWTVERYRPGETVPLVWERVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDE8</accession>
    <name>A0A1Q2CDE8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein-export membrane protein SecG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_04250</name>
        <name evidence="12" type="ORF">SAMN05428934_101454</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Involved in protein export. Participates in an early event of protein translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the SecG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY35746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04250"/>
    <dbReference type="EnsemblBacteria" id="AQP44121">
        <property type="protein sequence ID" value="AQP44121"/>
        <property type="gene ID" value="RPIT_04250"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY35746">
        <property type="protein sequence ID" value="SDY35746"/>
        <property type="gene ID" value="SAMN05428934_101454"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04250"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004692">
        <property type="entry name" value="SecG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03840">
        <property type="entry name" value="SecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01651">
        <property type="entry name" value="SECGEXPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00810">
        <property type="entry name" value="secG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY35746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="98" mass="10413" checksum="DE234CE7B75727A7" modified="2017-04-12" version="1">MEKHVPSVSIYRVIVPLVSWPVTTLSIIVVILSILLAATVLLHKGRGGGMSDLFGGGMSTSMGGASTAERRLDRITVVLALIWLLTIVGLLVLYRIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDG7</accession>
    <name>A0A1Q2CDG7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid ABC transporter ATP-binding protein, PAAT family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Glutamate ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_04245</name>
        <name evidence="6" type="ORF">SAMN05428934_101453</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY35721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04245"/>
    <dbReference type="EnsemblBacteria" id="AQP44120">
        <property type="protein sequence ID" value="AQP44120"/>
        <property type="gene ID" value="RPIT_04245"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY35721">
        <property type="protein sequence ID" value="SDY35721"/>
        <property type="gene ID" value="SAMN05428934_101453"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04245"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015424">
        <property type="term" value="F:ABC-type amino acid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030679">
        <property type="entry name" value="ABC_ATPase_HisP-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039085">
        <property type="entry name" value="ABC_ATPase_HisP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="8"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY35721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="247" mass="27166" checksum="64FFCD3C0D9536C3" modified="2017-04-12" version="1">MNDTRPLVEIDMVNKYFGTHHVLKDITTTVAEGEVVVVIGPSGSGKSTLCRAINRLETIDSGTITIDGQQLPEEGAQLAKLRSDVGMVFQSFNLFAHKTVLDNVTLAPIKVRRMKKADAEKRAMELLTRVGVEDHAHKMPAQLSGGQQQRVAIARSLAMDPKLILLDEPTSALDPEMINEVLDVMVELARAGMTMIVVTHEMGFARKAADRVIFMSDGAVVEEAEPDQFFTNPTSERAKDFLSKILH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDH3</accession>
    <name>A0A1Q2CDH3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04550</name>
        <name evidence="3" type="ORF">SAMN05428934_101516</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04550"/>
    <dbReference type="EnsemblBacteria" id="AQP44173">
        <property type="protein sequence ID" value="AQP44173"/>
        <property type="gene ID" value="RPIT_04550"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37289">
        <property type="protein sequence ID" value="SDY37289"/>
        <property type="gene ID" value="SAMN05428934_101516"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04550"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025289">
        <property type="entry name" value="DUF4081"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013653">
        <property type="entry name" value="FR47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13312">
        <property type="entry name" value="DUF4081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08445">
        <property type="entry name" value="FR47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="139"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY37289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="277" mass="30548" checksum="F96C1F1FF3AB015E" modified="2017-04-12" version="1">MTPRLRALGGADRHEALAFLAESPIENLFLASKIAAYGIDRRRLGNIHAFERDGRITSLLLDGGTVFVAGFDPEALPAFVGQLGPVRRCSSILGPSVSVLGLYVGLSERWKGSWGNVSNIRKRQPLMLLEQPPEAEADPRVRQLTRDDYTSYLDASVHMYTEEIGSSPFKYGSGYERFVMQRLVDRDAYGIVEDGKVIFKADLGPKLGRQAQLQGVWVDPALRGTGLSVPALSGMLRLAMVRYPQMSLYVNDFNAPAIRAYERLGFAEIGALATVHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDH8</accession>
    <name>A0A1Q2CDH8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4921 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Galactose-1-phosphate uridylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04305</name>
        <name evidence="3" type="ORF">SAMN05428934_101466</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY36045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04305"/>
    <dbReference type="EnsemblBacteria" id="AQP44130">
        <property type="protein sequence ID" value="AQP44130"/>
        <property type="gene ID" value="RPIT_04305"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY36045">
        <property type="protein sequence ID" value="SDY36045"/>
        <property type="gene ID" value="SAMN05428934_101466"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04305"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032576">
        <property type="entry name" value="DUF4921"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16268">
        <property type="entry name" value="DUF4921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DUF4921" evidence="1">
        <location>
            <begin position="14"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY36045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="441" mass="49833" checksum="E75F646F8356A6B2" modified="2017-04-12" version="1">MQPYSREPEYLSVLADGTVKQLNPFTGTEVWTVPGRGNRPLGINRPYPLPLNPDEEGRHCAFCERRYLDTPPEKSRVIRTEDGWETIYRSPAEDLFATVAEFRRIPNLYEILSFDYWHANYGFQLPGRVQQRKDAYLASPEGRAHVVSVIRGKLLSSGLSDEEVDALGAEDLVGQASGFFGGGHDLVVARRHFVDGAVDDSQLASSGTLSPDEHATFIRYTVESVRMAYDVNRYARYVTVFQNWLKPAGASFDHLHKQLVSIDERGVQHEATLAKLRNNGNLFNDVGANYAMYRNLVIAENEHALAFAGFGHRFPTIEIYSKSEQSDPWEMDRAEVRGMSDLIHAMHAATGPDVPCNEEWHYRPIDVSMPMPWRVMLKWRVSTLAGFEGATKIYLNTIPPTGLRDRVVAALRSLREKGLIVPDLMIGAEAQTRPNPLRYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDJ9</accession>
    <name>A0A1Q2CDJ9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44176">
        <property type="protein sequence ID" value="AQP44176"/>
        <property type="gene ID" value="RPIT_04565"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04565"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010279192" evidence="1">
        <location>
            <begin position="42"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="310" mass="32051" checksum="29CF8402F2EE177A" modified="2017-04-12" version="1">MSLTRRAALGAAVAALSGCAASPVVTGTPRPAPSPTPPVQAPEAAEAAASVAELAAVLGSLIDSPVWPEQPWAVAAKAQTDDHLGRLVALDPLGAEPRESFDVTVPTPTTYTDLAAAETALASSIDGTLPPLEAAAAAAPDPELRLLYASVAAATVGLRSRAQAPVAGDAQPRPLQDTTLEASLPVVLGHVWALIYGLGVGLGRLDRDDPLIGAGSERLDEARVLRNDLREMLPATAEPGQPAAFALPTAMDTAESIRAGWAELELRLLEAFGRLVAADPAPQWRETFLLQVPAAQNFGAALEYWPGWVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDL4</accession>
    <name>A0A1Q2CDL4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Polyribonucleotide nucleotidyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Polynucleotide phosphorylase</fullName>
            <shortName evidence="7">PNPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pnp</name>
        <name evidence="10" type="ORF">RPIT_04640</name>
        <name evidence="11" type="ORF">SAMN05428934_101535</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n)</text>
            <dbReference type="Rhea" id="RHEA:22096"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the polyribonucleotide nucleotidyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.8" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04640"/>
    <dbReference type="EnsemblBacteria" id="AQP44191">
        <property type="protein sequence ID" value="AQP44191"/>
        <property type="gene ID" value="RPIT_04640"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37723">
        <property type="protein sequence ID" value="SDY37723"/>
        <property type="gene ID" value="SAMN05428934_101535"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04640"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004654">
        <property type="term" value="F:polyribonucleotide nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01595">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014069">
        <property type="entry name" value="GPSI/PNP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012162">
        <property type="entry name" value="PNPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015848">
        <property type="entry name" value="PNPase_PH_RNA-bd_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036456">
        <property type="entry name" value="PNPase_PH_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11252">
        <property type="entry name" value="PTHR11252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03726">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005499">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46915">
        <property type="entry name" value="SSF46915"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="SSF54791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03591">
        <property type="entry name" value="polynuc_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02696">
        <property type="entry name" value="pppGpp_PNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S1 motif" evidence="9">
        <location>
            <begin position="652"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="515"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="521"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY37723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="733" mass="78869" checksum="CBDFE65AFF32461D" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDL7</accession>
    <name>A0A1Q2CDL7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Delta-aminolevulinic acid dehydratase</fullName>
            <ecNumber evidence="4 11">4.2.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">RPIT_04735</name>
        <name evidence="14" type="ORF">SAMN05428934_101556</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>2 5-aminolevulinate = H(+) + 2 H2O + porphobilinogen</text>
            <dbReference type="Rhea" id="RHEA:24064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="4.2.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homooctamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the ALAD family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.24" evidence="4 11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY38274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04735"/>
    <dbReference type="EnsemblBacteria" id="AQP44208">
        <property type="protein sequence ID" value="AQP44208"/>
        <property type="gene ID" value="RPIT_04735"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY38274">
        <property type="protein sequence ID" value="SDY38274"/>
        <property type="gene ID" value="SAMN05428934_101556"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04735"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00318"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004655">
        <property type="term" value="F:porphobilinogen synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001731">
        <property type="entry name" value="ALAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030656">
        <property type="entry name" value="ALAD_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11458">
        <property type="entry name" value="PTHR11458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00490">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001415">
        <property type="entry name" value="Porphbilin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00144">
        <property type="entry name" value="DALDHYDRTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01004">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00169">
        <property type="entry name" value="D_ALA_DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 11" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP44208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY38274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="321" mass="34114" checksum="7E286075D8BE88C8" modified="2017-04-12" version="1">MTQIRPRRLRTSPAMRALVREVAVRPSQLVLPTFVADEPGDISSMPGVNRLTVDDVARQAERAAALGLGGIMLFGVPSDDVKDADGTQGWAPDGILQRALRSVRSAVGDDIVVMADTCLDEFTSHGHCGVLGESGTVDNDATVAHYVSMAVAQAEAGAHVVSPSGMMDGQVAAIRSGLDDAGLQDTAILAYSAKYASAFYGPFREAVTSSLVGDRRTYQQDPANRREGLREALLDLAEGADMVMVKPAGYYLDVLSDVAAASQVPMAAYQVSGEFAMIEAAAERGWIDRRPAVEESVTAIVRAGADIVLTYWAEELAGWLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDM4</accession>
    <name>A0A1Q2CDM4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable nicotinate-nucleotide adenylyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Deamido-NAD(+) diphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Deamido-NAD(+) pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nicotinate mononucleotide adenylyltransferase</fullName>
            <shortName evidence="6">NaMN adenylyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nadD</name>
        <name evidence="8" type="ORF">RPIT_04695</name>
        <name evidence="9" type="ORF">SAMN05428934_101547</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + H(+) + nicotinate beta-D-ribonucleotide = deamido-NAD(+) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22860"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="EC" id="2.7.7.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Cofactor biosynthesis; NAD(+) biosynthesis; deamido-NAD(+) from nicotinate D-ribonucleotide: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NadD family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.18" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY38026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04695"/>
    <dbReference type="EnsemblBacteria" id="AQP44201">
        <property type="protein sequence ID" value="AQP44201"/>
        <property type="gene ID" value="RPIT_04695"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY38026">
        <property type="protein sequence ID" value="SDY38026"/>
        <property type="gene ID" value="SAMN05428934_101547"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04695"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00332"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004515">
        <property type="term" value="F:nicotinate-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02165">
        <property type="entry name" value="NMNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00244">
        <property type="entry name" value="NaMN_adenylyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005248">
        <property type="entry name" value="NadD/NMNAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00482">
        <property type="entry name" value="TIGR00482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4 6" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="7">
        <location>
            <begin position="21"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY38026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="222" mass="24411" checksum="36BAD6A4837C5A3D" modified="2017-04-12" version="1">MTTTELGIARAERQGRYRLGVMGGTFDPIHHGHLVAASEVASKFALDEVVFVPTGVPWQKRNRQVSLAEDRYLMTVIATASNPRFSVSRVDIDRPGDTYTVDTLKDLRAERGAQTDLFFITGADALRQILTWRGADELFNLAHFVGVTRPGVPLTQSDLAHLPEGGVTLLEVPALAISSTTCRERVRAQHPIWYLVPDGIVQYIAKRGLYPAAETGVPDDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDQ8</accession>
    <name>A0A1Q2CDQ8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44236">
        <property type="protein sequence ID" value="AQP44236"/>
        <property type="gene ID" value="RPIT_04915"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04915"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="277" mass="28552" checksum="1FD58937772C98F1" modified="2017-04-12" version="1">MTVIALGAHSATRGGPDTRSEWKWVRATWVAAAFIGGVAAWLVNGSLDLGRGTMLAPAIVGLFVVTGVGLAETVVRPRRPTGPRTASLAPRRVVNYLPRALTTAVAGITAVHLATLALTTASASADDMGRAGRQVAARCGNVGNGAGPYPGSFYSIPLTLLLLGIGLAAVAALVAVVRRPRGFANDDVSDDVLRLRSMTRVLAATGAAVAASHVGVAFFAGTALLRLDCQRAWMDPAGFVLVATIPVALLLLGWIVVRIVVPGALPAFSTAYPAEMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDS9</accession>
    <name>A0A1Q2CDS9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Trehalose 6-phosphate phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05140</name>
        <name evidence="4" type="ORF">SAMN05428934_101634</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Removes the phosphate from trehalose 6-phosphate to produce free trehalose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>alpha,alpha-trehalose 6-phosphate + H2O = alpha,alpha-trehalose + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23420"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58429"/>
            <dbReference type="EC" id="3.1.3.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan biosynthesis; trehalose biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the trehalose phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.12" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY40298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05140"/>
    <dbReference type="EnsemblBacteria" id="AQP44274">
        <property type="protein sequence ID" value="AQP44274"/>
        <property type="gene ID" value="RPIT_05140"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY40298">
        <property type="protein sequence ID" value="SDY40298"/>
        <property type="gene ID" value="SAMN05428934_101634"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05140"/>
    <dbReference type="UniPathway" id="UPA00299"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044651">
        <property type="entry name" value="OTSB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43768">
        <property type="entry name" value="PTHR43768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY40298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="275" mass="29159" checksum="8BAF7610BF17EE08" modified="2017-04-12" version="1">MSTWRSVTPHATEFLNAAAASSEGVLLALDFDGTLAPIVEDPLDSRFYEPAAEALGDLGPRVGKIAIITGRGVAVVRDLGQLQGRRGLDNLVVLGQYGVERWDAATGEETSPEVPSEVQAVRAEVDRLVAECPYRGVTVEDKGRALGIHTRRSDDPDGAFRDLKPKLRTLAEERGLVLEPGRNVLEIRASSTTKGQALLELADGMGATAVAFCGDDLGDLPAFEALAELRGRGVVTCAVVSGSDEQPEVARHADVLAEGPQGVADWLAELANRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDU5</accession>
    <name>A0A1Q2CDU5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 3">Acyl carrier protein</fullName>
            <shortName evidence="1">ACP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">acpP</name>
        <name evidence="5" type="ORF">RPIT_05200</name>
        <name evidence="6" type="ORF">SAMN05428934_101646</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 3">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="1">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.</text>
    </comment>
    <comment type="PTM">
        <text evidence="3">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY40596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05200"/>
    <dbReference type="EnsemblBacteria" id="AQP44283">
        <property type="protein sequence ID" value="AQP44283"/>
        <property type="gene ID" value="RPIT_05200"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY40596">
        <property type="protein sequence ID" value="SDY40596"/>
        <property type="gene ID" value="SAMN05428934_101646"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05200"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="Acyl_carrier"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="PTHR20863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00517">
        <property type="entry name" value="acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1 2 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="2"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="1 2">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY40596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="81" mass="8767" checksum="13B8AF632C2C7786" modified="2017-04-12" version="1">MASTEEIRADLAEIVNDIAGIATEDVQLDKSFVDDLGVDSLSMVEIIYGCEDKFGVEIPDEDAKNLKTVGDAVAYIERATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDY0</accession>
    <name>A0A1Q2CDY0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">L-lactate dehydrogenase complex protein LldG</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Lactate utilization protein C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05465</name>
        <name evidence="3" type="ORF">SAMN05428934_10340</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY66158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05465"/>
    <dbReference type="EnsemblBacteria" id="AQP44329">
        <property type="protein sequence ID" value="AQP44329"/>
        <property type="gene ID" value="RPIT_05465"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY66158">
        <property type="protein sequence ID" value="SDY66158"/>
        <property type="gene ID" value="SAMN05428934_10340"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05465"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003741">
        <property type="entry name" value="LUD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02589">
        <property type="entry name" value="LUD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LUD_dom" evidence="1">
        <location>
            <begin position="111"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY66158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="219" mass="23343" checksum="1461F0C9A288D846" modified="2017-04-12" version="1">MSAREDVLQLIRRATADVTERNPDVDVPVEWTYGRALPTADVIADFVEKVEDYKAAVRRCPEVGAAETIIEALSALDARSVVVPDGLPDAWVQALSGAGFELHRDEPVLSHAQLNSIDAVLTTAAVGMADSGTIALDHGDGQGRRALTLLPDRHIVVVREDQVVSDVPEGMARLAPALRARRPVTWLSGGSATSDIELSRVEGVHGPRHLSVVLVAGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDY7</accession>
    <name>A0A1Q2CDY7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05370</name>
        <name evidence="3" type="ORF">SAMN05428934_10321</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY65587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05370"/>
    <dbReference type="EnsemblBacteria" id="AQP44311">
        <property type="protein sequence ID" value="AQP44311"/>
        <property type="gene ID" value="RPIT_05370"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY65587">
        <property type="protein sequence ID" value="SDY65587"/>
        <property type="gene ID" value="SAMN05428934_10321"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05370"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="304"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="395"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY65587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="419" mass="45373" checksum="675543936DADBEC6" modified="2017-04-12" version="1">MTPLHGIASRSDLPLPFELVLAGGALVLVLTFWVALFAWKSPRFTERSGTPLPRLTRVVDAPAAVWSLRIVSIALWGLAAAALLFGVDRIDNPVFGFVFVLIWVGLVPVSLLFGTVYRRTNPIRLLLSRWETLNERTTGESWAPAAVALFAFLYLELVQPDGATLPVLRIFTALWFAWLVIGVLVRGPSWIARADPFEAYATSTARLSPWARDGAGTLLAINPLRNLASWRAPRHLALVAAVILGGTLFDALSNSAWWVRATQALDQAVYWPLGLAGLVASIGLIYGLFRLGALPYRDLTADDLAPGLIPLVVGYALAHYGTMLYLEGQRTLLRFSDPLARGWDLFGGAEAAPSTILFAFPTAVAIAQVVLIVGGHAIGVLVTHDIALRTRSRRVAVHLPLLSMMVVFTVGGLLLMFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE15</accession>
    <name>A0A1Q2CE15_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">dUTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05535</name>
        <name evidence="3" type="ORF">SAMN05428934_10354</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY66542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05535"/>
    <dbReference type="EnsemblBacteria" id="AQP44343">
        <property type="protein sequence ID" value="AQP44343"/>
        <property type="gene ID" value="RPIT_05535"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY66542">
        <property type="protein sequence ID" value="SDY66542"/>
        <property type="gene ID" value="SAMN05428934_10354"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05535"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025242">
        <property type="entry name" value="DUF4193"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13834">
        <property type="entry name" value="DUF4193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY66542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="98" mass="11006" checksum="0D9820AF6DE31555" modified="2017-04-12" version="1">MATDYDAPRKTDEEMSEDSLEELKSRRNDKNSGKVDEDEVEAAESFELPGADLSHEELTVRVLPRQADEFTCASCFLVKSRSQLAETKNGQPYCVDCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEA1</accession>
    <name>A0A1Q2CEA1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ASCH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06045"/>
    <dbReference type="EnsemblBacteria" id="AQP44428">
        <property type="protein sequence ID" value="AQP44428"/>
        <property type="gene ID" value="RPIT_06045"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06045"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007374">
        <property type="entry name" value="ASCH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009326">
        <property type="entry name" value="DUF984"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39203">
        <property type="entry name" value="PTHR39203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04266">
        <property type="entry name" value="ASCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01022">
        <property type="entry name" value="ASCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ASCH" evidence="1">
        <location>
            <begin position="39"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="161" mass="17176" checksum="BCB786069AE62A1D" modified="2017-04-12" version="1">MGGVDINTFWEHSRNGANLSPLAEWIGQRVRGTVPPPAVAFGQTPAEAEQLARAVLAGQKTTATSMLWQYDDDIPLPEMGDLAIVVDGAGTPRALILTTEVRVVPFSDVDEAHALGESASLEAWRNEQAAAATAADDGNHPLTPDTPMVLERYELLYPVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEB6</accession>
    <name>A0A1Q2CEB6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10 11">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="7 10 11">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rpe</name>
        <name evidence="15" type="ORF">RPIT_06130</name>
        <name evidence="16" type="ORF">SAMN05428934_103171</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1T</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1</strain>
        </source>
    </reference>
    <reference evidence="15" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="10 13">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 10 11">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="7 10 11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY69477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06130"/>
    <dbReference type="EnsemblBacteria" id="AQP44441">
        <property type="protein sequence ID" value="AQP44441"/>
        <property type="gene ID" value="RPIT_06130"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY69477">
        <property type="protein sequence ID" value="SDY69477"/>
        <property type="gene ID" value="SAMN05428934_103171"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06130"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00018"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019323">
        <property type="term" value="P:pentose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02227">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="PTHR11749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01163">
        <property type="entry name" value="rpe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01086">
        <property type="entry name" value="RIBUL_P_3_EPIMER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="13" id="KW-0170">Cobalt</keyword>
    <keyword evidence="9 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="138"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="169"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="191"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10 12">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10 12">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 14">
        <location>
            <position position="6"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13 14">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="AQP44441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="SDY69477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="217" mass="23565" checksum="316B78004FCF7C7F" modified="2017-04-12" version="1">MRITPSILNADFANLAAEISRIPDADAVHVDVMDNHFVPNLTLGLPVVESLRRATDKILDIHLMIEEPDRWAPAYAEAGAESVTFHVEACAAPIRLARELRRLGARAAMALKPATPIDGFADMLDEVDMVLLMTVEPGFGGQSFLDLVLPKIRRTRELLGDRPIWLQVDGGVSPDTIERCAEAGADTFVAGSAVYSADDPNAMVNRLRTLAVAACRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEQ2</accession>
    <name>A0A1Q2CEQ2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">LexA repressor</fullName>
            <ecNumber evidence="12">3.4.21.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">lexA</name>
        <name evidence="16" type="ORF">RPIT_07035</name>
        <name evidence="17" type="ORF">SAMN05428934_11037</name>
    </gene>
    <organism evidence="16 18">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 18" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1T</strain>
        </source>
    </reference>
    <reference evidence="17 19" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">RP1</strain>
        </source>
    </reference>
    <reference evidence="16" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Hydrolysis of Ala-|-Gly bond in repressor LexA.</text>
            <dbReference type="EC" id="3.4.21.88"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12 13">Belongs to the peptidase S24 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.88" evidence="12"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07035"/>
    <dbReference type="EnsemblBacteria" id="AQP44599">
        <property type="protein sequence ID" value="AQP44599"/>
        <property type="gene ID" value="RPIT_07035"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08764">
        <property type="protein sequence ID" value="SDZ08764"/>
        <property type="gene ID" value="SAMN05428934_11037"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07035"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06529">
        <property type="entry name" value="S24_LexA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00015">
        <property type="entry name" value="LexA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006200">
        <property type="entry name" value="LexA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039418">
        <property type="entry name" value="LexA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006199">
        <property type="entry name" value="LexA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006197">
        <property type="entry name" value="Peptidase_S24_LexA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01726">
        <property type="entry name" value="LexA_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00726">
        <property type="entry name" value="LEXASERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00498">
        <property type="entry name" value="lexA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12 13" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="4 12" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 12 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 12" id="KW-0678">Repressor</keyword>
    <keyword evidence="11 12" id="KW-0742">SOS response</keyword>
    <keyword evidence="9 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 12" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="LexA_DNA_bind" evidence="15">
        <location>
            <begin position="36"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S24" evidence="14">
        <location>
            <begin position="127"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="12">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="active site" description="For autocatalytic cleavage activity" evidence="12">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <feature type="active site" description="For autocatalytic cleavage activity" evidence="12">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="12">
        <location>
            <begin position="134"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="AQP44599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="SDZ08764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="245" mass="26646" checksum="6A138D4F93B4224A" modified="2017-04-12" version="1">MAEEKKRPRRGRPTNASVDAEYAEIAALPDAPAGNHGLTTRQLAILHVLRQSIEEVGYPPSIREIAQRANLASTSSVTYQLKVLEGKGFIRRDPNRPRALVVKLPGEGEGFDSAQTYDNKPNAVAAPLVGRIAAGGPILAEQHIEDVFALPRQLVGDGQVFMLEVKGDSMVEAAICDGDWVVVRRQDDAVNGDIVAALLDDEATVKTLRKKDGQVWLLPHNERYSPIDGTHAHVMGKVVAVIRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEQ5</accession>
    <name>A0A1Q2CEQ5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl-CoA thioesterase-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_06965</name>
        <name evidence="4" type="ORF">SAMN05428934_11052</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the C/M/P thioester hydrolase family.</text>
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        <property type="protein sequence ID" value="AQP44586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06965"/>
    <dbReference type="EnsemblBacteria" id="AQP44586">
        <property type="protein sequence ID" value="AQP44586"/>
        <property type="gene ID" value="RPIT_06965"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09115">
        <property type="protein sequence ID" value="SDZ09115"/>
        <property type="gene ID" value="SAMN05428934_11052"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06965"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR003703">
        <property type="entry name" value="Acyl_CoA_thio"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ09115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="280" mass="30846" checksum="E540C0F2A4E31C43" modified="2017-04-12" version="1">MPKDVAELIALFDLTETGPLSFRGPVPNTRLQRLFGGQVLGQTLVAASLTVPDDRLIHSLNAYFLRPGAIDTPLDFEVEVMRDGSTFSNRRIIARQADRVIFEMTASFQTPEEGLDHSAAEPTDVAPPESCPPLGEVLRRRFGANVEFLSEWDALDVRLAARPDKAEAGGTMKAWVRTRQALPDEPLLHAAVLAYLSDITLLSVTTVPHEVEFLSPSMQAASIDHAMWFHRPVRVDEWLLYDMTSPSASHARGFAVGRLFQRGEAVASCAQEGLIRVLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEW6</accession>
    <name>A0A1Q2CEW6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Competence/damage-inducible protein cinA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07105</name>
        <name evidence="3" type="ORF">SAMN05428934_11023</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07105"/>
    <dbReference type="EnsemblBacteria" id="AQP44610">
        <property type="protein sequence ID" value="AQP44610"/>
        <property type="gene ID" value="RPIT_07105"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08460">
        <property type="protein sequence ID" value="SDZ08460"/>
        <property type="gene ID" value="SAMN05428934_11023"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07105"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036653">
        <property type="entry name" value="CinA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008136">
        <property type="entry name" value="CinA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02464">
        <property type="entry name" value="CinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142433">
        <property type="entry name" value="SSF142433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00199">
        <property type="entry name" value="PncC_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CinA" evidence="1">
        <location>
            <begin position="2"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ08460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="159" mass="16588" checksum="800E22A09566C135" modified="2017-04-12" version="1">MSLAADVIKKMTERSLTLATCESLTGGGIGAALTSVPGASAVYRGGLVTYARDLKSSLAGVDEQLIADEGVVNELTAVQMAFGTQRRCNADWVVATTGVAGPEKIDGVDVGTVWFAVVGPKVGMSPAPQYTELTRFEGDREAIRGAAVEHAFAMLLRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEZ5</accession>
    <name>A0A1Q2CEZ5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07205</name>
        <name evidence="2" type="ORF">SAMN05428934_1103</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44625">
        <property type="protein sequence ID" value="AQP44625"/>
        <property type="gene ID" value="RPIT_07205"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08030">
        <property type="protein sequence ID" value="SDZ08030"/>
        <property type="gene ID" value="SAMN05428934_1103"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07205"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ08030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="203" mass="22071" checksum="17235998FADBC74F" modified="2017-04-12" version="1">MTTGDHPAVVALSAAIEDAAGLLRIPTDGVALEGMDAREWPDSCLGLGREDEVCTDAVTPGYLIRLGDGFTYHADQQGNVRRARDDVPHTDTEIRLRYSVSGGIAGQTTSYETDSYRLTRAEVDELRRLITEADFFNVPSSLPESPVADGITVRLWIAVGRRNHEVVRGDGINADDTEALEALVSWVADRTPARHPRVSGESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF16</accession>
    <name>A0A1Q2CF16_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07600</name>
        <name evidence="2" type="ORF">SAMN05428934_1212</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000021">
        <property type="protein sequence ID" value="SDZ22605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44687">
        <property type="protein sequence ID" value="AQP44687"/>
        <property type="gene ID" value="RPIT_07600"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ22605">
        <property type="protein sequence ID" value="SDZ22605"/>
        <property type="gene ID" value="SAMN05428934_1212"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07600"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ22605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="80" mass="8960" checksum="90DE81235EAF817B" modified="2017-04-12" version="1">MKVHTSALKHGVSAEDAVQAAEWALWIEPLADDEPPYRELRLGFDTRARLLETVVLVLVGGEELVIHAMPARKQYLDLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF35</accession>
    <name>A0A1Q2CF35_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07845</name>
        <name evidence="2" type="ORF">SAMN05428934_1139</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07845"/>
    <dbReference type="EnsemblBacteria" id="AQP44729">
        <property type="protein sequence ID" value="AQP44729"/>
        <property type="gene ID" value="RPIT_07845"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16163">
        <property type="protein sequence ID" value="SDZ16163"/>
        <property type="gene ID" value="SAMN05428934_1139"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07845"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ16163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="149" mass="15622" checksum="E25F9D08A9C1AC69" modified="2017-04-12" version="1">MSTPETEAANRQTQRELYGEPIADIVGRITSALGLTQGRLAEVIGLSAPMLSQLVSARRVKIGNPAVLARLQSLADLAVGPALSSEEREARLAAIHDEQPTMSTMRDAGAVHALRAAAPSEELQRLAQQTTAPELAALLRLAAGPSSHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF51</accession>
    <name>A0A1Q2CF51_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Imidazole glycerol phosphate synthase subunit HisF</fullName>
            <ecNumber evidence="9">4.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">IGP synthase cyclase subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">IGP synthase subunit HisF</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">ImGP synthase subunit HisF</fullName>
            <shortName evidence="9">IGPS subunit HisF</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hisF</name>
        <name evidence="11" type="ORF">RPIT_07985</name>
        <name evidence="12" type="ORF">SAMN05428934_11337</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">Heterodimer of HisH and HisF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9 10">Belongs to the HisA/HisF family.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07985"/>
    <dbReference type="EnsemblBacteria" id="AQP44752">
        <property type="protein sequence ID" value="AQP44752"/>
        <property type="gene ID" value="RPIT_07985"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16700">
        <property type="protein sequence ID" value="SDZ16700"/>
        <property type="gene ID" value="SAMN05428934_11337"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07985"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04731">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01013">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004651">
        <property type="entry name" value="HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00735">
        <property type="entry name" value="hisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 10" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="9">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDZ16700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="253" mass="26408" checksum="415A097545D80754" modified="2017-04-12" version="1">MAVALRVIPCLDVHDGRVVKGVNFTNLRDAGDPVELAAKYSADGADELTFLDISASSDGRATTREMVARCAETVFIPLTVGGGVREVSDVDLLLRAGADKVGINTGALARPGVIDEIARVFGNQVLVLSVDARREPGMPSGFGVTTHGGRRSAGVDAIEWAREACDRGVGEILLNSMDADGTTDGFDIEMLTAVRQVVDVPLIASGGAGTVEHFVEAARAGADAVLAASVFHYQSLTVAEVKDGLRTAGFEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF58</accession>
    <name>A0A1Q2CF58_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Segregation/condensation protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08040"/>
    <dbReference type="EnsemblBacteria" id="AQP44762">
        <property type="protein sequence ID" value="AQP44762"/>
        <property type="gene ID" value="RPIT_08040"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08040"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003768">
        <property type="entry name" value="ScpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33969">
        <property type="entry name" value="PTHR33969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02616">
        <property type="entry name" value="SMC_ScpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="275" mass="30153" checksum="BAD06711DEAB8E8C" modified="2017-04-12" version="1">MSRPRASDRHDGVAGFEVHLSNFEGPFDLLLQLISKRELDVTEVALSQVTDEFIAFVRLGGEIWDLEKTSAFLVVAATLLDLKAARLLPGGEVTDPEDIAALEARDLLFARLLQYRAFKKLAEWIAETMQAADTTHWRPGGLEEQFRSVMPEVELPITPDDLARLAAGAMTPRPAPVVDLGHLHGGAVSLTEQVNLIADRLRRDGSVTFRSLIAGADRMTVVVRFLAILELFRASQVGLDQMAPLAELTVRWTAGDDAAVEVTDDYGPQAELEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFA2</accession>
    <name>A0A1Q2CFA2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6 7">50S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplT</name>
        <name evidence="8" type="ORF">RPIT_08270</name>
        <name evidence="9" type="ORF">SAMN05428934_11521</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6 7">Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the bacterial ribosomal protein bL20 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08270"/>
    <dbReference type="EnsemblBacteria" id="AQP44794">
        <property type="protein sequence ID" value="AQP44794"/>
        <property type="gene ID" value="RPIT_08270"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19429">
        <property type="protein sequence ID" value="SDZ19429"/>
        <property type="gene ID" value="SAMN05428934_11521"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08270"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07026">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00382">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005813">
        <property type="entry name" value="Ribosomal_L20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035566">
        <property type="entry name" value="Ribosomal_protein_L20_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10986">
        <property type="entry name" value="PTHR10986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00453">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00062">
        <property type="entry name" value="RIBOSOMALL20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74731">
        <property type="entry name" value="SSF74731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01032">
        <property type="entry name" value="rplT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00937">
        <property type="entry name" value="RIBOSOMAL_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ19429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="122" mass="13812" checksum="4D15796B723B5424" modified="2017-04-12" version="1">MARVKRSVNAMKKRREVLEQASGYRGQRSRLYRKAKEQLLHSATYSYRDRRAKKGDFRSLWIQRINAAVRAEGMTYNRFINGLKNAGVEVDRKILAELAVNDTAAFNALVAIAKDNQPAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFF3</accession>
    <name>A0A1Q2CFF3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44846">
        <property type="protein sequence ID" value="AQP44846"/>
        <property type="gene ID" value="RPIT_08635"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08635"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013021226" evidence="1">
        <location>
            <begin position="27"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="64" mass="6701" checksum="6E1E7718C43AFAE1" modified="2017-04-12" version="1">MIRTFLRKTVAALVLAAVAMPATALAAQASPAVAPLLEQSGVTITQPGAKPNFHLCLIFPCRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFG6</accession>
    <name>A0A1Q2CFG6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">16S rRNA (Guanine(966)-N(2))-methyltransferase RsmD</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">16S rRNA (Guanine966-N2)-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_08705</name>
        <name evidence="4" type="ORF">SAMN05428934_10751</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08705"/>
    <dbReference type="EnsemblBacteria" id="AQP44859">
        <property type="protein sequence ID" value="AQP44859"/>
        <property type="gene ID" value="RPIT_08705"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97309">
        <property type="protein sequence ID" value="SDY97309"/>
        <property type="gene ID" value="SAMN05428934_10751"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08705"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031167">
        <property type="term" value="P:rRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004398">
        <property type="entry name" value="RNA_MeTrfase_RsmD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004553">
        <property type="entry name" value="CHP00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00095">
        <property type="entry name" value="TIGR00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY97309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="191" mass="20438" checksum="C7CDFE6DB9D0556E" modified="2017-04-12" version="1">MTRIIAGAAKGRRLTTPKSDLTRPTTDRTREALFSALTSWFDSADAEAHRQLEGVAVLDLYAGSGAVGLEAASRGAGPVLLVEHDRPTARLIQTNAKSTGLSVEVRAAKAEAVAAEPGDAFDFIFLDPPYGASTDVVDTLLMSLAEGRLAPRGLVVVERSSRDRAPAWPAAYTEVWDRRYGETTLHFGAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFH9</accession>
    <name>A0A1Q2CFH9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_08440</name>
        <name evidence="10" type="ORF">SAMN05428934_12012</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000020">
        <property type="protein sequence ID" value="SDZ22329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08440"/>
    <dbReference type="EnsemblBacteria" id="AQP44820">
        <property type="protein sequence ID" value="AQP44820"/>
        <property type="gene ID" value="RPIT_08440"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ22329">
        <property type="protein sequence ID" value="SDZ22329"/>
        <property type="gene ID" value="SAMN05428934_12012"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08440"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
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    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="92"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="152"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ22329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="370" mass="38989" checksum="E2A4E3F09DDF7E1F" modified="2017-04-12" version="1">MSGRAAGLRWGTRTFLTLALVVCAGVVTAALVALAVGPPLFHQHLLELGGSVGAAQMDHVEQAFIDAGSASLGVGLAVALLLATALAWLETRRLSRPLNALTTASAQLEAGDLAARVPRDTTPEFDAVAVAFNDMAERLHSTEESRRRLLGDVAHELRTPLATLSAELEAVIDDVLPWDAASQDVLIHQVERLRLIAQDLDDVSRAEEGRFTLDRREVATEELIAPVVAAAAGRFEAKGVQLRSIIDDGPVWADPQRVGQILSNLLDNALRHTPAGGNVTVTAHRDRTAVIVTVTDTGDGLSADQLQHVFERFYRADAARARDAGGSGIGLTIARSLALAHDGSLTASSTGPGNGSTFTLVLPAPQTRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFQ3</accession>
    <name>A0A1Q2CFQ3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09235</name>
        <name evidence="3" type="ORF">SAMN05428934_107158</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP44946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44946">
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        <property type="gene ID" value="RPIT_09235"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY99437"/>
        <property type="gene ID" value="SAMN05428934_107158"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09235"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY99437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="104" mass="11393" checksum="88B9E4C05D67062D" modified="2017-04-12" version="1">MDLRAIQALLVDPRADPSGVALGATMLGIVPVFLLGLFGYFLFPDSESYWSTAGVAVHLLMGTFLYCAAKHLLVRLVHMSNRVTWIDDGLSLLLSAAWALRLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFW0</accession>
    <name>A0A1Q2CFW0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mannose-1-phosphate guanylyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Mannose-1-phosphate guanylyltransferase (GDP)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09610</name>
        <name evidence="3" type="ORF">SAMN05428934_102384</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY59355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09610"/>
    <dbReference type="EnsemblBacteria" id="AQP45012">
        <property type="protein sequence ID" value="AQP45012"/>
        <property type="gene ID" value="RPIT_09610"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59355">
        <property type="protein sequence ID" value="SDY59355"/>
        <property type="gene ID" value="SAMN05428934_102384"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09610"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY59355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="359" mass="38888" checksum="2C87C3AA40012CB4" modified="2017-04-12" version="1">MRYVVIMAGGSGTRLWPLSRQGRPKQLLGLFEGKSLLRLAFERLDGLVPPDRILVCTGRAYADDVADQLPELSPVNILGEPEGRDSLNAVAWSAAVVADRDPDAVVAMVTADQVISPVDEFQRSLTLAFEVAEQRPSALVTLGVVPTSAHTGYGYLHRAELLTGFDGVYHVAEFKEKPERDVAQRYLDSGEYWWNAGMFVWRAATLLGQLDQLLPATAQTVREIVARPDRLDELFPTLQKISVDYAVMEPVSQGRTDAEVVSVGLAIDWRDVGGFVSLAELLSRDAGGNAVDGRTVSLDSRGCVVVNAVGPDHVVATLGLTDCLVVATPHATMVANLDDAERVRQLVDLVRTEAGPEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG20</accession>
    <name>A0A1Q2CG20_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_09895</name>
        <name evidence="9" type="ORF">SAMN05428934_102327</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0410 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY57656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45061">
        <property type="protein sequence ID" value="AQP45061"/>
        <property type="gene ID" value="RPIT_09895"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57656">
        <property type="protein sequence ID" value="SDY57656"/>
        <property type="gene ID" value="SAMN05428934_102327"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09895"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007341">
        <property type="entry name" value="Transgly_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33884">
        <property type="entry name" value="PTHR33884"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04226">
        <property type="entry name" value="Transgly_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY57656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="87" mass="8870" checksum="5BA6A444A8B4DA6A" modified="2017-04-12" version="1">MGTIIAYIVIGLLGGAIAKAIMPGRQGGGWVATILLGIVGALLGGFLGGLLFNVSYDEIFSVSGLIFSVLGALLVLVIYGFVTKNRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG67</accession>
    <name>A0A1Q2CG67_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative zinc-finger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_10145</name>
        <name evidence="4" type="ORF">SAMN05428934_102276</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45106">
        <property type="protein sequence ID" value="AQP45106"/>
        <property type="gene ID" value="RPIT_10145"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56303">
        <property type="protein sequence ID" value="SDY56303"/>
        <property type="gene ID" value="SAMN05428934_102276"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10145"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041916">
        <property type="entry name" value="Anti_sigma_zinc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027383">
        <property type="entry name" value="Znf_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13490">
        <property type="entry name" value="zf-HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="zf-HC2" evidence="2">
        <location>
            <begin position="6"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY56303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="475" mass="50747" checksum="55D279CD6610FFBD" modified="2017-04-12" version="1">MGSGRCDRFHADLSAYVDGTLPHRRCEQVSHHIADCETCRDEVASISSVCSTLSACARSSAPSSLTSKLESIAGEHAEAPLYMAPGRGELPSTRRRRQRLVTQGGAALLVAAMSVMVLAVLIAPDPRRLDDPVRAAREQFSRATAAVSVNEALGAVLLAHERGADLGAPISYEPLTGGSIDVVISETRAADWLRRAADADLSLTGVQRVWISDGSGLYRSAEVRTTKLEGYGAELEVLDARGDRFSSSFLPEATPGKVEASKRWSFTESFWSERVAGREAIRLTATDKHGLVASWWLDLETDLVLWSERYDGTGEVSLAFGYTELSFDEPTFDTDTSLTQLISLQPASASEQDGWCVGLEHCPQSVAGLPLVAYASSEQRDGSSMTLVYSDGFETAVVGWTDGVLVGGETSRTHREPGMPTVMAWQSGPAVVSVTSTGTTDLLAEVAEALPAEEPHAESLLDRTVAGLGRLVGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGB0</accession>
    <name>A0A1Q2CGB0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-2 type transport system ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_10345</name>
        <name evidence="6" type="ORF">SAMN05428934_102236</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10345"/>
    <dbReference type="EnsemblBacteria" id="AQP45143">
        <property type="protein sequence ID" value="AQP45143"/>
        <property type="gene ID" value="RPIT_10345"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55214">
        <property type="protein sequence ID" value="SDY55214"/>
        <property type="gene ID" value="SAMN05428934_102236"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10345"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY55214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="304" mass="32149" checksum="5D7F0E2D19E53FCC" modified="2017-04-12" version="1">MAEAVTVRAVGKVFHARHSVVEALDDVTFSVARGEIVALMGANGAGKSTLLDLICGLTTPTSGDVRVFGQAPRDAVLAGRLGAMLQMGGLLPDLTVAETVRLIASFYDRPIDVDEVLRTAGVEDIAGRRIAVCSGGEQQRVKFALALLPGAPLLVLDEPTAGMDWRARSAFWERMRMLTAEGRTLLYSSHYADEVEAVADRVVVLAEGRLVADIGTDEISAAAPTRVVQVDSGPRCTADALRALPGVRSADVDSGRVDLVVDAEHVSELVVHLLSTCGAGNLQVLGPPFFESLDALISQARRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGB2</accession>
    <name>A0A1Q2CGB2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10115</name>
        <name evidence="3" type="ORF">SAMN05428934_102282</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10115"/>
    <dbReference type="EnsemblBacteria" id="AQP45100">
        <property type="protein sequence ID" value="AQP45100"/>
        <property type="gene ID" value="RPIT_10115"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56469">
        <property type="protein sequence ID" value="SDY56469"/>
        <property type="gene ID" value="SAMN05428934_102282"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10115"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY56469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="166" mass="18163" checksum="406D3626E02CEC84" modified="2017-04-12" version="1">MTQPPVIPNKILQLNYPQHVAEYPTYEEAQAAVDYLADEKFAVENILIVGTNLRLLERVTGRRTWGSVLGEGAVSGISTGLLVGLMLVLFVGNGNWAMLWVGLAMGIVFGVLFRALAYSLSGGKRDFNSARQTVATSYEILAEHRVAQEARDLLARRPGARAAQFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGC9</accession>
    <name>A0A1Q2CGC9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">M18 family aminopeptidase</fullName>
            <ecNumber evidence="10">3.4.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_10495</name>
        <name evidence="12" type="ORF">SAMN05428934_102206</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the peptidase M18 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.-" evidence="10"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY54324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10495"/>
    <dbReference type="EnsemblBacteria" id="AQP45171">
        <property type="protein sequence ID" value="AQP45171"/>
        <property type="gene ID" value="RPIT_10495"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY54324">
        <property type="protein sequence ID" value="SDY54324"/>
        <property type="gene ID" value="SAMN05428934_102206"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10495"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001948">
        <property type="entry name" value="Peptidase_M18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023358">
        <property type="entry name" value="Peptidase_M18_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570">
        <property type="entry name" value="PTHR28570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02127">
        <property type="entry name" value="Peptidase_M18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00932">
        <property type="entry name" value="AMINO1PTASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9 11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 9" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP45171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY54324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="421" mass="44666" checksum="68E4D36D69CB9770" modified="2017-04-12" version="1">MLNTASEHIDSLADFVAESPTSLHAAAAIAERLRQAGFEQADPAQSWSSVSGRRFVLRDGAVIAWVAPEELAERSGFRIVGTHTDSPSFKVKPGDPIRSAGWTQVGVEVYGGPLLNSWLDRDLGIAGRVVTRDGVSHLVRTGPVARIPQLAVHLDRGVNDALKLDKQTSTQPVLAIEMPGSLLDHLCEPIEVSPDDVALHDLFVYDTQRPAVIGMEKEFLASGRLDNLACTHGALSAVEDLQAGSDVAVFAAFDHEEVGSATTTGAAGPILQDVLERIAAGYGLALDATRAMYARSSCISADTGHVVHPNYPNHHDPINKPLPNRGPLLKLNANQRYATDGVGAALWMRACAAADVPTQPFVSSNAVPCGSTIGPITATRLGITTVDVGVGLLSMHSARELCGVDDPWYLARAVEAYWNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGF3</accession>
    <name>A0A1Q2CGF3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mycothiol S-conjugate amidase</fullName>
            <ecNumber evidence="2">3.5.1.115</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mca</name>
        <name evidence="3" type="ORF">RPIT_10560</name>
        <name evidence="4" type="ORF">SAMN05428934_102193</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + mycothiol S-conjugate = 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + an N-acetyl-L-cysteine-S-conjugate</text>
            <dbReference type="Rhea" id="RHEA:36543"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58718"/>
            <dbReference type="ChEBI" id="CHEBI:58886"/>
            <dbReference type="ChEBI" id="CHEBI:59633"/>
            <dbReference type="EC" id="3.5.1.115"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MshB deacetylase family. Mca subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.115" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY53890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10560"/>
    <dbReference type="EnsemblBacteria" id="AQP45183">
        <property type="protein sequence ID" value="AQP45183"/>
        <property type="gene ID" value="RPIT_10560"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY53890">
        <property type="protein sequence ID" value="SDY53890"/>
        <property type="gene ID" value="SAMN05428934_102193"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10560"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010126">
        <property type="term" value="P:mycothiol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010127">
        <property type="term" value="P:mycothiol-dependent detoxification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01482">
        <property type="entry name" value="Mca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017811">
        <property type="entry name" value="Mca"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="PTHR12993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993:SF16">
        <property type="entry name" value="PTHR12993:SF16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03446">
        <property type="entry name" value="mycothiol_Mca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY53890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="298" mass="33325" checksum="476712448FC53C3C" modified="2017-04-12" version="1">MTRADLPRLRLLHVHAHPDDESSKGAATTAKYVAEGVDVMVATCTGGERGSVLNPKLAGDPTVEANIAEIRRREMARAREILGVEQVWLGFVDSGLPEGDPPPPLPTGCFGTLDPRVAAGPLVRVIREFRPHVVTTYDEQGGYPHPDHIMCHRITVEAFNAAADPTAWPEHGPPWQAAKLYYHMSFHRRRFEQLERAMHEAGLECHFPARDEDPYSYGRLTTFVHCAEYFPVRDEALRAHATQIDPDGPWFAVPLAIQQAGWPTEDYQLVVSKVPTMIPEDDLFKGLRPEPLVPEFMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGG6</accession>
    <name>A0A1Q2CGG6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribose-phosphate pyrophosphokinase</fullName>
            <shortName evidence="6">RPPK</shortName>
            <ecNumber evidence="6">2.7.6.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">5-phospho-D-ribosyl alpha-1-diphosphate</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phosphoribosyl diphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phosphoribosyl pyrophosphate synthase</fullName>
            <shortName evidence="6">P-Rib-PP synthase</shortName>
            <shortName evidence="6">PRPP synthase</shortName>
            <shortName evidence="6">PRPPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">prs</name>
        <name evidence="8" type="ORF">RPIT_10740</name>
        <name evidence="9" type="ORF">SAMN05428934_102157</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 2 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY52805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10740"/>
    <dbReference type="EnsemblBacteria" id="AQP45212">
        <property type="protein sequence ID" value="AQP45212"/>
        <property type="gene ID" value="RPIT_10740"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY52805">
        <property type="protein sequence ID" value="SDY52805"/>
        <property type="gene ID" value="SAMN05428934_102157"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10740"/>
    <dbReference type="UniPathway" id="UPA00087">
        <property type="reaction ID" value="UER00172"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009156">
        <property type="term" value="P:ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00583_B">
        <property type="entry name" value="RibP_PPkinase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000842">
        <property type="entry name" value="PRib_PP_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037515">
        <property type="entry name" value="Rib-P_diPkinase_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="PTHR10210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00114">
        <property type="entry name" value="PRPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran_N" evidence="7">
        <location>
            <begin position="11"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Ribose-5-phosphate binding" evidence="6">
        <location>
            <begin position="232"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="44"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="103"/>
            <end position="104"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY52805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="324" mass="35353" checksum="19F5438A2DB0CDB9" modified="2017-04-12" version="1">MSQIAKNDKHLMLFSGRAFPELAQEVATLMGEELVPTRALTYANSEIYVRFEESVRGCDAFVIQSHTAPVNEWIMEQLIMVDALKRASAKRITVVAPFYPYARQDKKHLGREPISARLVADLYKAAGADRIMSVDLHASQIQGFFDGPVDHLWGLPVLSDYVKEKYDTSEMAIVSPDAGRVRLADLWTDYLGCPLAIIHKRRDANKANTVEVHEVVGDVQGKTCLLVDDMIDTAGTIVQAAAALRERGAARVICAATHAVFSGPAAERLNASDMEEIIVTNTLPIKTPEPVQNLTVLSIAPLIAKAINAVFLDGSVTSLFGGHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGP8</accession>
    <name>A0A1Q2CGP8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7 8">N-acetylglucosamine-6-phosphate deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_11120</name>
        <name evidence="8" type="ORF">SAMN05428934_10280</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="5">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the metallo-dependent hydrolases superfamily. NagA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY50420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11120"/>
    <dbReference type="EnsemblBacteria" id="AQP45277">
        <property type="protein sequence ID" value="AQP45277"/>
        <property type="gene ID" value="RPIT_11120"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY50420">
        <property type="protein sequence ID" value="SDY50420"/>
        <property type="gene ID" value="SAMN05428934_10280"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11120"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008448">
        <property type="term" value="F:N-acetylglucosamine-6-phosphate deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003764">
        <property type="entry name" value="GlcNAc_6-P_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113:SF14">
        <property type="entry name" value="PTHR11113:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038994">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="6">
        <location>
            <begin position="45"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR038994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY50420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="378" mass="39835" checksum="B18E3790B6AD2B03" modified="2017-04-12" version="1">MSIEELSVARAVTPDGVVDNAVITIEDGRIVSVTSGGSGGLKLWAVPGFVDTHCHGAVGVSYGNPDRAANMRAIEYHRRQGTTTTFASTVTEPIEKLEAQLAVLRALYDDGELAGIHLEGPFLAEAKKGAHDAALLRDPDPESVERLISAGGPALKMITMAVERDHSEEATRRFIEAGVHVAFGHSDADDVTTALSIEWGADIATHLFSAMRSIHHREPGPVPVLLSDERVMVELICDGVHHKAVIAAMSIDAAGPERVALVTDAMSATGHGDGRYILGELEVDVLDGTARLVTADGTPGAIAGSTLTMAKAFEFVVWEVGVSIPDAALMAATTPARWHGLTDVGELAAGRLADICLVDDEGALHGVIRHGEWIVSPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGQ2</accession>
    <name>A0A1Q2CGQ2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_11160</name>
        <name evidence="2" type="ORF">SAMN05428934_10272</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY50179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11160"/>
    <dbReference type="EnsemblBacteria" id="AQP45284">
        <property type="protein sequence ID" value="AQP45284"/>
        <property type="gene ID" value="RPIT_11160"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY50179">
        <property type="protein sequence ID" value="SDY50179"/>
        <property type="gene ID" value="SAMN05428934_10272"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11160"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021391">
        <property type="entry name" value="DUF3027"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11228">
        <property type="entry name" value="DUF3027"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY50179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="257" mass="27446" checksum="589208DA69A7AEC2" modified="2017-04-12" version="1">MAKPKLDAVAAGAVDLARNAAVEVGGADAVGEHLGVSPEEGERLVTHYFESRVPGYDDWQWAVTLVRATRAKTATVNEIVLLPRADALLAPQWVPWEDRIGAGDIAPGMLMATPDNDPRLEPGFAATDLPVDADNADWVQLRSTVSELGLGRARVLSRFGRDEATERWLDGPPGPNNEETREAPANCGTCGYFVALRGSLGVLFGACTNQYSPSDGRVVSLDHGCGGHSDVVAEERPRELPAPVFDTISIDEGSLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGS8</accession>
    <name>A0A1Q2CGS8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Molybdopterin molybdenumtransferase</fullName>
            <ecNumber evidence="7">2.10.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_11025</name>
        <name evidence="10" type="ORF">SAMN05428934_10298</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo-molybdopterin</text>
            <dbReference type="Rhea" id="RHEA:35047"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.10.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the MoeA family.</text>
    </comment>
    <dbReference type="EC" id="2.10.1.1" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY50960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11025"/>
    <dbReference type="EnsemblBacteria" id="AQP45260">
        <property type="protein sequence ID" value="AQP45260"/>
        <property type="gene ID" value="RPIT_11025"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY50960">
        <property type="protein sequence ID" value="SDY50960"/>
        <property type="gene ID" value="SAMN05428934_10298"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11025"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061599">
        <property type="term" value="F:molybdopterin molybdotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032324">
        <property type="term" value="P:molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00887">
        <property type="entry name" value="MoeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038987">
        <property type="entry name" value="MoeA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005111">
        <property type="entry name" value="MoeA_C_domain_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036688">
        <property type="entry name" value="MoeA_C_domain_IV_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005110">
        <property type="entry name" value="MoeA_linker/N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036135">
        <property type="entry name" value="MoeA_linker/N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192">
        <property type="entry name" value="PTHR10192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03454">
        <property type="entry name" value="MoeA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03453">
        <property type="entry name" value="MoeA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63867">
        <property type="entry name" value="SSF63867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63882">
        <property type="entry name" value="SSF63882"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6 7" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="8">
        <location>
            <begin position="207"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY50960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="430" mass="46333" checksum="525EDAB8146B3CE6" modified="2017-04-12" version="1">MAWFGRKKQDDDVVEEEIIEEPRLPEPPAADAQGLRSVADHTAYLLELVEPLKPFGMSLLEAWDQVMCEDIDSMINVPPASTAKVAGYAVRASDLLDDEGHLAPPLAIVDADVDHLPADAAVVVGAGDVLPRGANAVLPSSFAAVEENHVRLIEKVSAGEYLRAAGEHLRQGTRLLSEGDVLGERAIGLLASAGVDKVLVRPRPRVVVVSSGEHLVEPGAEIRHGDVADTNSFMIAAAARAIGATVFRVAVHSNDPDAIREAITDQLIRADLVISTTGGRREDYETVASVMRDLGLVDSVDVLMTPGRTQTFGLIGDERVPMLMLPGNPVSAYVSFHAFARPLIRRLMGARTEHRAVRAIASGTLRSLRGQMHLLRGRVWSEGSVRHVEQVSAPHALTELARSNALIVLDDGIETVRPGEAVKVWLIEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGV1</accession>
    <name>A0A1Q2CGV1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11110</name>
        <name evidence="3" type="ORF">SAMN05428934_10282</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY50478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11110"/>
    <dbReference type="EnsemblBacteria" id="AQP45275">
        <property type="protein sequence ID" value="AQP45275"/>
        <property type="gene ID" value="RPIT_11110"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY50478">
        <property type="protein sequence ID" value="SDY50478"/>
        <property type="gene ID" value="SAMN05428934_10282"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11110"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="46"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY50478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="248" mass="26635" checksum="0E912F1B4673187A" modified="2017-04-12" version="1">MADPMRWFGSRQPGAVEAVLGRAYGGGSTPYEWLSRAVSKSAVTVLDLACGAGAMIDRLQRDGRTVIGLDRSAEELALARERGRGPLVQAHASYLPFADGSFDAVVTSLGFAVVADRPRFLAEAARVLRPGGVFAALTPSVRPANVEDLRVVSRLAGYLRVTPHVPGITEFKANQALSAVGLTKAEDKRARYYFEVSSREDAELLLGGLRSSPDRGRASSAVDFMTARVESLGPLRVPLPMRRIIAIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH09</accession>
    <name>A0A1Q2CH09_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mak_N_cap domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11820</name>
        <name evidence="3" type="ORF">SAMN05428934_106111</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11820"/>
    <dbReference type="EnsemblBacteria" id="AQP45402">
        <property type="protein sequence ID" value="AQP45402"/>
        <property type="gene ID" value="RPIT_11820"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93109">
        <property type="protein sequence ID" value="SDY93109"/>
        <property type="gene ID" value="SAMN05428934_106111"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11820"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040999">
        <property type="entry name" value="Mak_N_cap"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18085">
        <property type="entry name" value="Mak_N_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mak_N_cap" evidence="1">
        <location>
            <begin position="24"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY93109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="190" mass="20445" checksum="C4244B3DAB9CE8BB" modified="2017-04-12" version="1">MSGAAEVHPNATLTPTKIELLQRWLPTQDWFRGDAERVRQATRFRLVDPDGAVGLDAIIAAAGEAAYFVPLTWRDAPLEGATLVGTLEHSELGTRYGYDATTDPVFRTEVERVIREADSHSEIHDQAGNALPLDSTASGSGVVGEPAGEILDFVRVLDRAADVPIDAVGTLTVAWTDDEGPRSDVVALLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH30</accession>
    <name>A0A1Q2CH30_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11560</name>
        <name evidence="3" type="ORF">SAMN05428934_106163</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY94282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45355">
        <property type="protein sequence ID" value="AQP45355"/>
        <property type="gene ID" value="RPIT_11560"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY94282">
        <property type="protein sequence ID" value="SDY94282"/>
        <property type="gene ID" value="SAMN05428934_106163"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11560"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY94282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="179" mass="19273" checksum="B81FDEA01047BF73" modified="2017-04-12" version="1">MQSERFAVGLTPLPTAARVTRQRSALRMRILSTVISMALLVAIIWFLGRDWSTAWTVGLVIAWVASSAFWFVLSVVGLQRAKRDLASIDEGVAFYLDPQGIEFVHPTPARISWQELSALKLVGRNFGAGPSIVAEAGGRRVAGVPVSFLDASPAVIDSAARAYSLGRANLDTAALDHLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHC5</accession>
    <name>A0A1Q2CHC5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-2 type transport system ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_12490</name>
        <name evidence="6" type="ORF">SAMN05428934_104188</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY80245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45519">
        <property type="protein sequence ID" value="AQP45519"/>
        <property type="gene ID" value="RPIT_12490"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY80245">
        <property type="protein sequence ID" value="SDY80245"/>
        <property type="gene ID" value="SAMN05428934_104188"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12490"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY80245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="300" mass="31819" checksum="BA0969A6ED25920C" modified="2017-04-12" version="1">MIETTSVSKRLGAKQVLHDVSLQARDGHVTGFVGPNGAGKTTLMKIIAGLLPADSGTALIDGVPFTQAAVPGRALGVYMSGEWLPTRRSGSDHLRFVCDTQSIPAARVRPMLETVGLWGVHDRAIGTYSLGMRQRLGIAAALIGDPVNIMLDEPVNGLDPGGVIWLRELLKEQAAHGKAVLLSSHLMSELELVADRVVMLHEGQVVRAGTLAELSTRENRPEVYIASTELAAVLELLHRQGLDTRPEGDGALVAGADPEQVGRIVFGAGLTLSHLAPNVHSLEDLFLSSTSTSQKQESAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHD5</accession>
    <name>A0A1Q2CHD5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted Fe-Mo cluster-binding protein, NifX family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12505</name>
        <name evidence="3" type="ORF">SAMN05428934_104185</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY80156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12505"/>
    <dbReference type="EnsemblBacteria" id="AQP45522">
        <property type="protein sequence ID" value="AQP45522"/>
        <property type="gene ID" value="RPIT_12505"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY80156">
        <property type="protein sequence ID" value="SDY80156"/>
        <property type="gene ID" value="SAMN05428934_104185"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12505"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003731">
        <property type="entry name" value="Di-Nase_FeMo-co_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036105">
        <property type="entry name" value="DiNase_FeMo-co_biosyn_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02579">
        <property type="entry name" value="Nitro_FeMo-Co"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53146">
        <property type="entry name" value="SSF53146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitro_FeMo-Co" evidence="1">
        <location>
            <begin position="16"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY80156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="112" mass="12186" checksum="1BBCF919610B3C3C" modified="2017-04-12" version="1">MIIATPIDPEGRSAHSWGKAQWIGVADVRDGSVADWTVHEVRWDESHDAGTHGSHHARVVRFLKEQQIEAVVVDHVGDGMARTLHTMGIPTLQSSPGYAQASVLAALRGHHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHE8</accession>
    <name>A0A1Q2CHE8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">dTDP-glucose 4,6-dehydratase</fullName>
            <ecNumber evidence="4 6">4.2.1.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_12645</name>
        <name evidence="9" type="ORF">SAMN05428934_104157</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O</text>
            <dbReference type="Rhea" id="RHEA:17221"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57477"/>
            <dbReference type="ChEBI" id="CHEBI:57649"/>
            <dbReference type="EC" id="4.2.1.46"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 6">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.46" evidence="4 6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY79374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12645"/>
    <dbReference type="EnsemblBacteria" id="AQP45548">
        <property type="protein sequence ID" value="AQP45548"/>
        <property type="gene ID" value="RPIT_12645"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY79374">
        <property type="protein sequence ID" value="SDY79374"/>
        <property type="gene ID" value="SAMN05428934_104157"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12645"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008460">
        <property type="term" value="F:dTDP-glucose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009225">
        <property type="term" value="P:nucleotide-sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05246">
        <property type="entry name" value="dTDP_GD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005888">
        <property type="entry name" value="dTDP_Gluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01181">
        <property type="entry name" value="dTDP_gluc_dehyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="7">
        <location>
            <begin position="5"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY79374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="332" mass="36769" checksum="D7A1CDEEC34B0097" modified="2017-04-12" version="1">MTSLLVTGGAGFIGSNFVHWALANTDANVTVLDALTYAGNLSSLGGLSAERFQFVNGSVTSPGLVSELVEASDVVVHFAAESHNDNSLEGPGVFIDTNIVGTYHVLQAVRQHQKRLHHISTDEVYGDLELDDPAKFTPATPYNPSSPYSASKAASDHLVRAWVRSFGVQATISNCSNNYGPRQHIEKFIPRQITNIIDGHRPKLYGAGLNVRDWIHVDDHNSAVWRIIEEGAIGETYLIGADGEKSNREVIELILELMGLEPDGYDHVNDRAGHDLRYAIDATKLREELGWEPRYTDFSEGLDETITWYEDNETWWRPMKDATEAKYAAKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHF4</accession>
    <name>A0A1Q2CHF4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_12615</name>
        <name evidence="6" type="ORF">SAMN05428934_104163</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY79552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45542">
        <property type="protein sequence ID" value="AQP45542"/>
        <property type="gene ID" value="RPIT_12615"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY79552">
        <property type="protein sequence ID" value="SDY79552"/>
        <property type="gene ID" value="SAMN05428934_104163"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12615"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="15"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="166"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY79552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="238" mass="25369" checksum="7B3EABE6C28C358E" modified="2017-04-12" version="1">MATADPPPTGTRPLRVVVADDQSLVRMGLRLVLESDEAVRVVGEAGDGEAAVERCRELRPDVALLDVQMPRATGLEATARILEASPGTRVIILTTFDLDEYVYDALRAGASGFLLKDAAPAELLSAVHAVAAGEAVIAPRITRRLLERFAPRLPDPASPTPADGASHPRLAALTARELDVLRLVAQGFSNAEIADQLFLSPTTVKTHVSSLLAKLQARDRVHAVIVAYETGLVPRPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHK6</accession>
    <name>A0A1Q2CHK6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH tetR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_12885</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12885"/>
    <dbReference type="EnsemblBacteria" id="AQP45591">
        <property type="protein sequence ID" value="AQP45591"/>
        <property type="gene ID" value="RPIT_12885"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12885"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="10"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="190" mass="20992" checksum="DEA1B51D55691AFB" modified="2017-04-12" version="1">MTRAAPMPPDERRASLIDATLPLLLQHGPSLTTRQVAEAAGVAEGTIFRAFNSLPDLIDATTREAMSAERLTRELDSLELGDTLDEKVTTTLELFTTRFARIRTLLMAAHAREHHTSECMRDELASRRAELDAWLTSRFAVHADELCTSPETLVSYLRTLAHGHALTLPPSPLSTADLTRLALHGARKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHK8</accession>
    <name>A0A1Q2CHK8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phage_sheath_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_12630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the myoviridae tail sheath protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45545">
        <property type="protein sequence ID" value="AQP45545"/>
        <property type="gene ID" value="RPIT_12630"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12630"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035089">
        <property type="entry name" value="Phage_sheath_subtilisin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04984">
        <property type="entry name" value="Phage_sheath_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_sheath_1" evidence="2">
        <location>
            <begin position="248"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="500" mass="51997" checksum="7E9886CAE46933C2" modified="2017-04-12" version="1">MSFSAPGVYVEEVPRGPRPIEPLATSVTAFVGRAVRGPVDRAVAVGDMAGFESVFGALTVDSGLGYGVRAFFANGGRSAVIVRVDDGGATAQVDLGGGLVVEAVGPGSWANGLVVGVSHPSPDEAAAAASVQGLATGDDIFTLWLTLDGHTELFPHVTLVDGPRRLDAVLQASTLARVRSPLTTTRPAPGNYPVSTPGADGQVPAVDAYVSGAGEKRGITALDDVDLVNLLVLPPASPDIALPDGVWAAALAYAQQRRAFLIVDPPPGMPGSDIPDWLVGVGLTGAAARNAAIYYPRVDQRDPLSGGAVRSFAPSGAVAGVYARMDAARGVWKAPAGLEAALADVVGPSVVLTDPENGDLNRVGVNAIRAIDRVGTVVWGARTLRGADAHADEYKYVPVRRLALHLEESVIRSLDWTVFEPNGEPLWARIRQVVGDFMQQMFRQGAFAGAAPREAYVVKCDAETTTPADIAGGVVEVLVGFAPLKPAEFIIFKVRTRAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHL0</accession>
    <name>A0A1Q2CHL0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cytochrome bd-I ubiquinol oxidase subunit 1 apoprotein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="13">Cytochrome ubiquinol oxidase subunit I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">RPIT_12920</name>
        <name evidence="14" type="ORF">SAMN05428934_104103</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the cytochrome ubiquinol oxidase subunit 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12920"/>
    <dbReference type="EnsemblBacteria" id="AQP45597">
        <property type="protein sequence ID" value="AQP45597"/>
        <property type="gene ID" value="RPIT_12920"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY77846">
        <property type="protein sequence ID" value="SDY77846"/>
        <property type="gene ID" value="SAMN05428934_104103"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12920"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070069">
        <property type="term" value="C:cytochrome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002585">
        <property type="entry name" value="Cyt-d_ubiquinol_oxidase_su_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30365">
        <property type="entry name" value="PTHR30365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01654">
        <property type="entry name" value="Cyt_bd_oxida_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006446">
        <property type="entry name" value="Cyt_quinol_oxidase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 12" id="KW-0349">Heme</keyword>
    <keyword evidence="10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="179"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="391"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="443"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR006446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP45597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY77846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="493" mass="54310" checksum="A477F1DEC709EAD1" modified="2017-04-12" version="1">MDQVTLARWQFGITTVYHFLFVPITIAMSMLVAIMQTMWVRTGKDAYLRLTKFFGKLFLINFALGVVTGIVQEFQFGMNWSEYSRFVGDVFGAPLALEALLAFFLESTFIGLWIFGWDKLPKKIHLLTIYMAAFGTMLSAVFILAANSWMQNPVGTTFNNGRAEIAGIEGFLEVLTNPVLLVTVPHVLSGAYMVAGGLVAAIGGWHLAKINRDGEAKPGDEQAYRFATKFGAWVLLAASVVTVISGDQQSKIMTEVQPMKMAAAEGLFYTEQNASFSIFTIGNREGTEPILELRIPGLLSLMSGHDEVKGINNLRDEYNAEGFKRFDGSQTQLQEEFAETLAANYDVDPMPNVAISYWTFRLMIGLGFAGIALAAFTLWVVRKDRLPKPGLLWTVGMFAMPLLPLFANSFGWIFTEMGRQPWVVAGVMPTAAGVSPTVSAGTVLFSMIVYTLLYGALAVIEVWLFLKYAKAGLPDVAPVELQTDPDAPMTFAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHL2</accession>
    <name>A0A1Q2CHL2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lysine--tRNA ligase</fullName>
            <ecNumber evidence="6">6.1.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lysyl-tRNA synthetase</fullName>
            <shortName evidence="6">LysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lysS</name>
        <name evidence="9" type="ORF">RPIT_12735</name>
        <name evidence="10" type="ORF">SAMN05428934_104140</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys)</text>
            <dbReference type="Rhea" id="RHEA:20792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9696"/>
            <dbReference type="Rhea" id="RHEA-COMP:9697"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6 7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6 7">Binds 3 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.6" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY78865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12735"/>
    <dbReference type="EnsemblBacteria" id="AQP45563">
        <property type="protein sequence ID" value="AQP45563"/>
        <property type="gene ID" value="RPIT_12735"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY78865">
        <property type="protein sequence ID" value="SDY78865"/>
        <property type="gene ID" value="SAMN05428934_104140"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12735"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04322">
        <property type="entry name" value="LysRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00252">
        <property type="entry name" value="Lys_tRNA_synth_class2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002313">
        <property type="entry name" value="Lys-tRNA-ligase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044136">
        <property type="entry name" value="Lys-tRNA-ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018149">
        <property type="entry name" value="Lys-tRNA-synth_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00982">
        <property type="entry name" value="TRNASYNTHLYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00499">
        <property type="entry name" value="lysS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="190"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="416"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY78865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="506" mass="56155" checksum="DA271E002D7CBC2A" modified="2017-04-12" version="1">MLRVNDAPLPQPSDSEQTAIRKEKRARLLESGTEVYPADLTRSHTLREIRATWGHLEAGVETDEVVTTGGRVVFIRNTGKLAFATLQDGFTPDDNGERLQVMLSLAEVGEEALAAWKADADLGDFIWVKGRVIASKRGELSIMASEWRFAAKALRPLPVMHKDLSEESRVRRRYVDLIVRDEAREMVRKRSAITRAVRDTLYDHGYLEVETPTLQLVHGGAAARPFNTHINAFDIDMTLRIALELHLKRTMVGGADRVFEIGRVFRNEGIDSTHSAEFTMLEAYQAWGDQKTIARLIQDIIVASADAVGSRQIETPRGTIDLDGEWAWLPVYPALSEKVGQPITVDTPADVLQGIAEANEVEYDPKWGADKLVMELFGDLVEPDLIQPTFVYDYPALAQPLARPHRTEPGKIEAWDLIIGGVERGTGFTELIDPIIQRDVLTSQSLKAAAGDPEAMQFDQDFIEALEYGVPPMGGLGLGIDRLIMLLTGVGIRETILFPLLRPSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHM7</accession>
    <name>A0A1Q2CHM7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_13095</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyltransferase 87 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13095"/>
    <dbReference type="EnsemblBacteria" id="AQP45628">
        <property type="protein sequence ID" value="AQP45628"/>
        <property type="gene ID" value="RPIT_13095"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13095"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018584">
        <property type="entry name" value="GT87"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09594">
        <property type="entry name" value="GT87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="189"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="346"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="431"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="454" mass="48596" checksum="FF84F65C760FB439" modified="2017-04-12" version="1">MGRHAKPRGLWFNPLPWAMLAATLTFLVLFLRHLPCLQTDADNAINSYIRLCYSDIQSSFLGQEFALGTPALGGEQMLFSPLVAVAITMATQASRLMGSVGPGQTLQQQIDTSTAFFGWTALGLFLCFLVTAASFAWLGRRGDGRSWDSLLIAGSPIVLAAGLISWELLPLALTALGLVQFARRRLFEAGIVLGLAASAGTMPIAIILAVLVAAGLRGGAVTALKFFLPAVVTVVGVHAPLLLDDVGAVYGYYHQEINKEAGYGSLWYLFSLGGWETRHTGSLAFAILMLVLGLLVAYLYTARKRPRVGSLIAVIVLLTVLLGPAYPPQTSLWVLLAVMLARPYKVELIAVTVTEVGYYLAIWGWLAGSLTSAQQGPYGLYWLAIILRASIQGLVAWEALSDIVRPGRDELRTPDQPDPIGGVLNDDEFAAHVGSEDSPQDAEPVAATTGAELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHQ6</accession>
    <name>A0A1Q2CHQ6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glyoxylase, beta-lactamase superfamily II</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Zn-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13170</name>
        <name evidence="4" type="ORF">SAMN05428934_10453</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY76480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13170"/>
    <dbReference type="EnsemblBacteria" id="AQP45641">
        <property type="protein sequence ID" value="AQP45641"/>
        <property type="gene ID" value="RPIT_13170"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY76480">
        <property type="protein sequence ID" value="SDY76480"/>
        <property type="gene ID" value="SAMN05428934_10453"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13170"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="23"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY76480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="207" mass="22416" checksum="E20AC06D53351357" modified="2017-04-12" version="1">MTARIEHLATAGNHDPQGPPVHENNVWLVGDDTEVIIVDPAHDASAVERAVGGRRVVAALLTHGHWDHIRAARDFAARVDCQLHLHPADAFLWEAEHGDAPFEPIADGERFAVAGTELEARRTPGHTPGSTSFAVADLRAVLTGDTLFEGGPGATRWDYASFETILDSIQRRLFVLPDDTVVHTGHGPSTTIGAERPALPDWIARGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHS5</accession>
    <name>A0A1Q2CHS5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA-binding transcriptional regulator, ArsR family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13365</name>
        <name evidence="3" type="ORF">SAMN05428934_10414</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY75336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP45676">
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        <property type="protein sequence ID" value="SDY75336"/>
        <property type="gene ID" value="SAMN05428934_10414"/>
    </dbReference>
    <dbReference type="GeneID" id="63021855"/>
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    </dbReference>
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        <property type="entry name" value="SSF46785"/>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="4"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP45676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY75336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="119" mass="12704" checksum="010B33627FE0445A" modified="2017-04-12" version="1">MLTIASRLDVMNRLGRALADPTRSRIILTLLDHPAYPAELARDLDLTRPNVSNHLACLRDCGIVVSEPEGRRTRYEIADSHLAQALTALVDATLAVDEDAPCIDPACSLPGCDAAGEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHU8</accession>
    <name>A0A1Q2CHU8_9ACTN</name>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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            <strain evidence="3 4">RP1T</strain>
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    </dbReference>
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            <begin position="226"/>
            <end position="264"/>
        </location>
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        <location>
            <begin position="272"/>
            <end position="300"/>
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="300" mass="32269" checksum="C8D84D8F020E1E32" modified="2017-04-12" version="1">MPEVGPHPELAAVLAEATARRRGRNGLPRGASVRLIGDDRQLSAIGAGGVLRDLRRVHGAVELDEVLRFVNNGEKAASLALRQGDPTALGWYLDHDRIHAGSSDTALDGALQAWKADTDHGPNSLMLASTRLDVAELNRRARQVLAGKDGLGVRLSDGNLAGVGDVIVTRRNDRRLRTSTTGFVMNGDRWIVQAVNRNGGLLVRHRTTGHRAWLPAAYVVDHTELGYATTIHTAQGSTVDTAHTVLSGTETRQLLYVAMTRGRQANHSYVTTVGHGDPHSAFTPETLRPRDSTTGVDCVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHV3</accession>
    <name>A0A1Q2CHV3_9ACTN</name>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">RPIT_13425</name>
        <name evidence="3" type="ORF">SAMN05428934_1043</name>
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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                <person name="Lal R."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="RPIT_13425"/>
    </dbReference>
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        <property type="gene ID" value="SAMN05428934_1043"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <begin position="2"/>
            <end position="113"/>
        </location>
    </feature>
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            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP45687.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY75050.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="114" mass="12322" checksum="A2F38BF0DEEE6276" modified="2017-04-12" version="1">MAVTAIDIRVEDVEGATRLLSEAYGWRVLTDDANFGEVDAGGVRIMLSREAMVPWGVTDGIILHHSVEDVVEAARVAEKAGAQLLDGPLRTDWGTETAYLRGPGNVIVSVFRDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHX6</accession>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="component" value="Chromosome"/>
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        <property type="entry name" value="DUF721/UPF0232"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="28"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="175" mass="19401" checksum="7BA109A173979A62" modified="2017-04-12" version="1">MSDEPHDPTGLDLASEIARAAVESAAYGVVLPDPAPQRQPRRPRRPMEQQRSGAHPDDRDPQLVGDVLDSVIKQRGWQRRISLSTLLRRWPELVGEANAEHSTPVDYTDGVLIVDCDSTAWASAMRYSASQLVARLNRSLGDRTVLRVDFRGPKPPSWKRGPRSVGGRGPRDTYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI28</accession>
    <name>A0A1Q2CI28_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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        <lineage>
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    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13930"/>
    <dbReference type="EnsemblBacteria" id="AQP45767">
        <property type="protein sequence ID" value="AQP45767"/>
        <property type="gene ID" value="RPIT_13930"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ11785">
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        <property type="gene ID" value="SAMN05428934_11113"/>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ11785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="116" mass="12405" checksum="83E404A882B72DFB" modified="2017-04-12" version="1">MFELLTDGTVESLCRRLSQAGVRYGFGGVARLGRGDLPAERIVAEHVRLGSSMAILSRAFCDLREHEATLSAMDAGFFEANRQQVVDVVAEIAARKGPHLSAKVRPVQAISAGVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIB1</accession>
    <name>A0A1Q2CIB1_9ACTN</name>
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        <recommendedName>
            <fullName evidence="3 8">30S ribosomal protein S6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpsF</name>
        <name evidence="9" type="ORF">RPIT_14500</name>
        <name evidence="10" type="ORF">SAMN05428934_109116</name>
    </gene>
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    </organism>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Binds together with S18 to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14500"/>
    <dbReference type="EnsemblBacteria" id="AQP45868">
        <property type="protein sequence ID" value="AQP45868"/>
        <property type="gene ID" value="RPIT_14500"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06813">
        <property type="protein sequence ID" value="SDZ06813"/>
        <property type="gene ID" value="SAMN05428934_109116"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14500"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00473">
        <property type="entry name" value="bS6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00360">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_S6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020815">
        <property type="entry name" value="Ribosomal_S6_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020814">
        <property type="entry name" value="Ribosomal_S6_plastid/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_S6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribosomal_S6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011">
        <property type="entry name" value="PTHR21011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="SSF54995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00166">
        <property type="entry name" value="S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01048">
        <property type="entry name" value="RIBOSOMAL_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ06813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="102" mass="11830" checksum="199FE88C996613D3" modified="2017-04-12" version="1">MRKYEIMVLIDSDVDERQVPALVEKHLEVITKDGGTVDNTDIWGRRRLAYDINKKSEAIYAVLQVTAEPASVKEMDRLMSIDERVVRTKVLRLEEPKDNKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIC5</accession>
    <name>A0A1Q2CIC5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted Kef-type K+ transport protein, K+/H+ antiporter domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_14565</name>
        <name evidence="7" type="ORF">SAMN05428934_109101</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45879">
        <property type="protein sequence ID" value="AQP45879"/>
        <property type="gene ID" value="RPIT_14565"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06527">
        <property type="protein sequence ID" value="SDZ06527"/>
        <property type="gene ID" value="SAMN05428934_109101"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14565"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="76"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="169"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="5">
        <location>
            <begin position="391"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ06527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="534" mass="56742" checksum="655C436C3CD319BE" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CID2</accession>
    <name>A0A1Q2CID2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplI</name>
        <name evidence="9" type="ORF">RPIT_14515</name>
        <name evidence="10" type="ORF">SAMN05428934_109113</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bL9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14515"/>
    <dbReference type="EnsemblBacteria" id="AQP45871">
        <property type="protein sequence ID" value="AQP45871"/>
        <property type="gene ID" value="RPIT_14515"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06757">
        <property type="protein sequence ID" value="SDZ06757"/>
        <property type="gene ID" value="SAMN05428934_109113"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14515"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.430.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00503">
        <property type="entry name" value="Ribosomal_L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000244">
        <property type="entry name" value="Ribosomal_L9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_L9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020594">
        <property type="entry name" value="Ribosomal_L9_bac/chp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020069">
        <property type="entry name" value="Ribosomal_L9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036791">
        <property type="entry name" value="Ribosomal_L9_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020070">
        <property type="entry name" value="Ribosomal_L9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036935">
        <property type="entry name" value="Ribosomal_L9_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21368">
        <property type="entry name" value="PTHR21368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03948">
        <property type="entry name" value="Ribosomal_L9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01281">
        <property type="entry name" value="Ribosomal_L9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55653">
        <property type="entry name" value="SSF55653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="SSF55658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00158">
        <property type="entry name" value="L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00651">
        <property type="entry name" value="RIBOSOMAL_L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RIBOSOMAL_L9" evidence="8">
        <location>
            <begin position="13"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ06757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="148" mass="15970" checksum="91E3075796CDA372" modified="2017-04-12" version="1">MKLILTSTVDKLGIAGDVVEVKDGYGRNFLLPQGKAIRWTRGTEKQIEGIKRARDAREVRGVEHAQELRTQLEGLTVKIPARVSEQGHLFGSVTTSDLAVAVKKAGGPTIDKRTVSFAKPVKTLGAHTAAVKLHQAVTAHVPFEVVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIE9</accession>
    <name>A0A1Q2CIE9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14750</name>
        <name evidence="3" type="ORF">SAMN05428934_10970</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14750"/>
    <dbReference type="EnsemblBacteria" id="AQP45908">
        <property type="protein sequence ID" value="AQP45908"/>
        <property type="gene ID" value="RPIT_14750"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05921">
        <property type="protein sequence ID" value="SDZ05921"/>
        <property type="gene ID" value="SAMN05428934_10970"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14750"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="9"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ05921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="105" mass="11413" checksum="C41689EAB45355EA" modified="2017-04-12" version="1">MLDSSAVDTTTLAPSEALAVLQAVADPIRYAILDELAGRCRCVCDLQERIEIAPNLLSYHLRVLREANLITGTRRGRWVDYSLAPGALDRMHAALPAPRLAGCQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIF5</accession>
    <name>A0A1Q2CIF5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Site-specific DNA recombinase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Transposon DNA-invertase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_14595</name>
        <name evidence="8" type="ORF">SAMN05428934_10995</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the site-specific recombinase resolvase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_023434504.1">
        <property type="nucleotide sequence ID" value="NZ_FNPU01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14595"/>
    <dbReference type="EnsemblBacteria" id="AQP45884">
        <property type="protein sequence ID" value="AQP45884"/>
        <property type="gene ID" value="RPIT_14595"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06412">
        <property type="protein sequence ID" value="SDZ06412"/>
        <property type="gene ID" value="SAMN05428934_10995"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14595"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006118">
        <property type="entry name" value="Recombinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00398">
        <property type="entry name" value="RECOMBINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51736">
        <property type="entry name" value="RECOMBINASES_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0229">DNA integration</keyword>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="6">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-serine intermediate" evidence="5">
        <location>
            <position position="9"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606118-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ06412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="222" mass="24333" checksum="5381AE1A6FD60321" modified="2017-04-12" version="1">MLIGYARVSKADGSQSLDLQHDTLRAAGVERDNIYDDLASGGRDDRPGLTACLKSLRDGDVLVVWKLDRLGRSLAHLVNTVKELSDRKIGLRVLTGKGAQIDTTTASGRMVFGIFATLAEFERDLIRERTMAGLASARARGRKGGRKFALTKAQVRLAQAAMAQRDTSVSDLCKELGIERVTLYRYVGPKGELRDHGKHVLGLTSQLVSFRKLSHLRASSEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIJ6</accession>
    <name>A0A1Q2CIJ6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_01450</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01450"/>
    <dbReference type="EnsemblBacteria" id="AQP45956">
        <property type="protein sequence ID" value="AQP45956"/>
        <property type="gene ID" value="RPIT_01450"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01450"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="34"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="234" mass="25291" checksum="46AE7294C1328A26" modified="2017-04-12" version="1">MRELSPRDGASWDERGWPYRIPAVRQVLREGLALGQATVLVGENGSGKSTLVEALAEGYGLNPEGGSTGAMHSTRRTESDLSAQLQVVRGGGASKGGYFLRAETMHSFYSYLEDVGMASFHTRSHGEGFVELIETRCFGPGGPRPGLYLFDEVESALSFNSSLRVLATLMDLLAEPGAQIVLATHSPVLAALPGATILELDGDGLHETAWGDLEAVISERYFLADPERFLRHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIK6</accession>
    <name>A0A1Q2CIK6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_01700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01700"/>
    <dbReference type="EnsemblBacteria" id="AQP45966">
        <property type="protein sequence ID" value="AQP45966"/>
        <property type="gene ID" value="RPIT_01700"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01700"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006780">
        <property type="term" value="P:uroporphyrinogen III biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06578">
        <property type="entry name" value="HemD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003754">
        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039793">
        <property type="entry name" value="UROS/Hem4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40082">
        <property type="entry name" value="PTHR40082"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="SSF69618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TP_methylase" evidence="3">
        <location>
            <begin position="16"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="HEM4" evidence="4">
        <location>
            <begin position="255"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="500"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="525" mass="55612" checksum="AD92D41CC77AC602" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIK7</accession>
    <name>A0A1Q2CIK7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2-amino-3-ketobutyrate coenzyme A ligase</fullName>
            <shortName evidence="1">AKB ligase</shortName>
            <ecNumber evidence="1">2.3.1.29</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glycine acetyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">kbl</name>
        <name evidence="3" type="ORF">RPIT_00595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + glycine = (2S)-2-amino-3-oxobutanoate + CoA</text>
            <dbReference type="Rhea" id="RHEA:20736"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78948"/>
            <dbReference type="EC" id="2.3.1.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
        <text evidence="1">Binds 1 pyridoxal phosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-threonine degradation via oxydo-reductase pathway; glycine from L-threonine: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.29" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00595"/>
    <dbReference type="EnsemblBacteria" id="AQP45942">
        <property type="protein sequence ID" value="AQP45942"/>
        <property type="gene ID" value="RPIT_00595"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00595"/>
    <dbReference type="UniPathway" id="UPA00046">
        <property type="reaction ID" value="UER00506"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008890">
        <property type="term" value="F:glycine C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019518">
        <property type="term" value="P:L-threonine catabolic process to glycine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00985">
        <property type="entry name" value="2am3keto_CoA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011282">
        <property type="entry name" value="2am3keto_CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01822">
        <property type="entry name" value="2am3keto_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="35"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="1">
        <location>
            <begin position="107"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="1">
        <location>
            <begin position="204"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="1">
        <location>
            <begin position="235"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding; shared with dimeric partner" evidence="1">
        <location>
            <begin position="268"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="362"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="389" mass="42065" checksum="05B8FC437B5D2D8F" modified="2017-04-12" version="1">MRDELASLREQGLYKEEAALTTPQSARIGVVDGREVLNLCANNYLGLADSPVLIEAAKKALDEWGFGMASVRFICGTQTLHQRLEAALTQFLHPGADGWDTILYSSCFDANGGLFEVLFSEGDAIISDELNHASIIDGVRLSKAARYRYRNRDMADLEAQLIAAKDARFKIVVTDGVFSMDGYVAPLDEICDLAEKHGALVMVDDSHAVGFVGATGAGTPERFGVQDRVDIVTGTLGKALGGASGGYTCARAEVVEMLRQRSRPYLFSNSLAPSIAAAALATLDLLKESSELRDQLNANTAYFREQMVARGFEIPESDHAIVPVMIGDAVMAAKMADEILARGVYVRAFSYPVVPKGKARIRTQMSAALTREDLDTAIRAFEDARAALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIL8</accession>
    <name>A0A1Q2CIL8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphoenolpyruvate carboxykinase [GTP]</fullName>
            <shortName evidence="8">PEP carboxykinase</shortName>
            <shortName evidence="8">PEPCK</shortName>
            <ecNumber evidence="8">4.1.1.32</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">GTP-dependent phosphoenolpyruvate carboxykinase</fullName>
            <shortName evidence="8">GTP-PEPCK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pckG</name>
        <name evidence="12" type="ORF">RPIT_01330</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>GTP + oxaloacetate = CO2 + GDP + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10388"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.1.1.32"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 1 Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.32" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01330"/>
    <dbReference type="EnsemblBacteria" id="AQP45952">
        <property type="protein sequence ID" value="AQP45952"/>
        <property type="gene ID" value="RPIT_01330"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01330"/>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004613">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (GTP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00819">
        <property type="entry name" value="PEPCK_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00452">
        <property type="entry name" value="PEPCK_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018091">
        <property type="entry name" value="PEP_carboxykin_GTP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008209">
        <property type="entry name" value="PEP_carboxykinase_GTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035077">
        <property type="entry name" value="PEP_carboxykinase_GTP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035078">
        <property type="entry name" value="PEP_carboxykinase_GTP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11561">
        <property type="entry name" value="PTHR11561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00821">
        <property type="entry name" value="PEPCK_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17297">
        <property type="entry name" value="PEPCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001348">
        <property type="entry name" value="PEP_carboxykinase_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="SSF68923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00505">
        <property type="entry name" value="PEPCK_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="5 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PEPCK_N" evidence="11">
        <location>
            <begin position="16"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="PEPCK_GTP" evidence="10">
        <location>
            <begin position="240"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="215"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="389"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="267"/>
            <end position="272"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="391"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="422"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="517"/>
            <end position="520"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP45952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="617" mass="69388" checksum="4D44A5A107A84CE3" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIM0</accession>
    <name>A0A1Q2CIM0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dihydropteroate synthase</fullName>
            <shortName evidence="1">DHPS</shortName>
            <ecNumber evidence="1">2.5.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Dihydropteroate pyrophosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_14665</name>
        <name evidence="4" type="ORF">SAMN05428934_10984</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DHPS family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.15" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_031966051.1">
        <property type="nucleotide sequence ID" value="NZ_FNPU01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14665"/>
    <dbReference type="EnsemblBacteria" id="AQP45895">
        <property type="protein sequence ID" value="AQP45895"/>
        <property type="gene ID" value="RPIT_14665"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06195">
        <property type="protein sequence ID" value="SDZ06195"/>
        <property type="gene ID" value="SAMN05428934_10984"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14665"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00156"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004156">
        <property type="term" value="F:dihydropteroate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00739">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="PTHR20941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01496">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00792">
        <property type="entry name" value="DHPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00793">
        <property type="entry name" value="DHPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pterin-binding" evidence="2">
        <location>
            <begin position="6"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ06195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="283" mass="30605" checksum="F04DB17FBA7F451E" modified="2017-04-12" version="1">MLRSRVTVFGILNLTEDSFFDESRRLDPAGAVTAAIEMLRVGSDVVDVGPAASHPDARPVSPADEIRRIAPLLDALSDQMHRVSIDSFQPETQRYALKRGVGYLNDIQGFPDPALYPDIAEADCRLVVMHSAQRDGIATRTGHLRPEDALDEIVRFFEARVSALRRSGVAADRLILDPGMGFFLSPAPETSLHVLSNLQKLKSALGLPLLVSVSRKSFLGATVGLPVKDLGPASLAAELHAIGNGADYVRTHAPGDLRSAITISETLAKFRSRDARDRGLDHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIN1</accession>
    <name>A0A1Q2CIN1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mycothiol acetyltransferase</fullName>
            <shortName evidence="2">MSH acetyltransferase</shortName>
            <ecNumber evidence="2">2.3.1.189</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Mycothiol synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mshD</name>
        <name evidence="4" type="ORF">RPIT_01785</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA = CoA + H(+) + mycothiol</text>
            <dbReference type="Rhea" id="RHEA:26172"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16768"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58887"/>
            <dbReference type="EC" id="2.3.1.189"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetyltransferase family. MshD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.189" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01785"/>
    <dbReference type="EnsemblBacteria" id="AQP45967">
        <property type="protein sequence ID" value="AQP45967"/>
        <property type="gene ID" value="RPIT_01785"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01785"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035447">
        <property type="term" value="F:mycothiol synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010125">
        <property type="term" value="P:mycothiol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01698">
        <property type="entry name" value="MshD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017813">
        <property type="entry name" value="Mycothiol_AcTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03448">
        <property type="entry name" value="mycothiol_MshD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="132"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Acetyl-CoA binding 1" evidence="2">
        <location>
            <begin position="61"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Acetyl-CoA binding 2" evidence="2">
        <location>
            <begin position="209"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Acetyl-CoA binding 2" evidence="2">
        <location>
            <begin position="216"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside</name>
            <dbReference type="ChEBI" id="CHEBI:58887"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside</name>
            <dbReference type="ChEBI" id="CHEBI:58887"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside</name>
            <dbReference type="ChEBI" id="CHEBI:58887"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside</name>
            <dbReference type="ChEBI" id="CHEBI:58887"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside</name>
            <dbReference type="ChEBI" id="CHEBI:58887"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="273" mass="29758" checksum="15DB9C14398B5C91" modified="2017-04-12" version="1">MREALLSLVADITKHDGVSPINESASLGIDGEREADFYFMGSRTDPHGFVVCDERDGTLMVGVHPDHRCRGVGTQLLDEALRSHPDSAVWAFGTLPGAEALAARVGLTPVRQLLRMERPLDPPSRVSMPEGFEIVAYTPDDAEAVVAINAAAFAHHPEQGRLSVGEFLQLTRQPWFDPAGLLIAKSNGVATGFHWTKRHGEGLGEVYVLAVAPDHEGRGLGRVLLEEGLNHLVQQGDDRVQLYVEAAETRVVNMYKAAGFDVAQTDTSYRVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIN9</accession>
    <name>A0A1Q2CIN9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">NADH-quinone oxidoreductase subunit L</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_02685</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02685"/>
    <dbReference type="EnsemblBacteria" id="AQP45981">
        <property type="protein sequence ID" value="AQP45981"/>
        <property type="gene ID" value="RPIT_02685"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02685"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018393">
        <property type="entry name" value="NADHpl_OxRdtase_5_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003945">
        <property type="entry name" value="NU5C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001516">
        <property type="entry name" value="Proton_antipo_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42829">
        <property type="entry name" value="PTHR42829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00662">
        <property type="entry name" value="Proton_antipo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01974">
        <property type="entry name" value="NDH_I_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="450"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="494"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="597"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_N" evidence="8">
        <location>
            <begin position="66"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="7">
        <location>
            <begin position="132"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="618" mass="66117" checksum="9631194BE3A45339" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIS5</accession>
    <name>A0A1Q2CIS5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05555"/>
    <dbReference type="EnsemblBacteria" id="AQP46036">
        <property type="protein sequence ID" value="AQP46036"/>
        <property type="gene ID" value="RPIT_05555"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05555"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022183">
        <property type="entry name" value="DUF3710"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12502">
        <property type="entry name" value="DUF3710"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="228" mass="24815" checksum="E09A1EFFE044BD52" modified="2017-04-12" version="1">MFGRKKQQTPETASPVSPESPDEVAPPVDDLDDAARWDAEFDRDEGPFDINEVDLSADEDEIKRLDLDTLVLTPFEGMTLQLQVDREREIVQSILVGDGQSALEVAVFAGPAKSSMAGEIRDEVLQVTQKQGGKAQVVRGPFGAEIRRALPVKDGEGKPAMHLSRTWLVPGPGWVLRGVLLGKATFEPDNDEAQTALTEFFSNVVVRRGTTPAAPGSLLPMRVPQQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIV9</accession>
    <name>A0A1Q2CIV9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 14">Crossover junction endodeoxyribonuclease RuvC</fullName>
            <ecNumber evidence="11 14">3.1.21.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Holliday junction nuclease RuvC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 14">Holliday junction resolvase RuvC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ruvC</name>
        <name evidence="15" type="ORF">RPIT_06330</name>
        <name evidence="16" type="ORF">SAMN05428934_103211</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1T</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1</strain>
        </source>
    </reference>
    <reference evidence="15" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 14">Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 14">
            <text>Endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).</text>
            <dbReference type="EC" id="3.1.21.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 14">Belongs to the RuvC family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.10" evidence="11 14"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06330"/>
    <dbReference type="EnsemblBacteria" id="AQP46051">
        <property type="protein sequence ID" value="AQP46051"/>
        <property type="gene ID" value="RPIT_06330"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70554">
        <property type="protein sequence ID" value="SDY70554"/>
        <property type="gene ID" value="SAMN05428934_103211"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06330"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16962">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00034">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020563">
        <property type="entry name" value="X-over_junc_endoDNase_Mg_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002176">
        <property type="entry name" value="X-over_junc_endoDNase_RuvC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30194">
        <property type="entry name" value="PTHR30194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02075">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00696">
        <property type="entry name" value="RSOLVASERUVC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00228">
        <property type="entry name" value="ruvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01321">
        <property type="entry name" value="RUVC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 14" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="16" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 14" id="KW-0540">Nuclease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="14">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="AQP46051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="SDY70554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="172" mass="17961" checksum="D7BC91AA7AC6E8C3" modified="2017-04-12" version="1">MRVIGIDPGLTRCGVGIVEGTVGRLPTMIALGVVRTSPSLDVARRLVELESGLEEYFNRYAPEAVAIERVFSQHNLASVMDTAQAAGVAALVGARRGLSVTFHTPSEVKAAVSGSGSAGKAQVTQMVMRILRLEVAPKPADAADALAIAVTHVWRGGATNRYAAAVAAAKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ83</accession>
    <name>A0A1Q2CJ83_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09380"/>
    <dbReference type="EnsemblBacteria" id="AQP46105">
        <property type="protein sequence ID" value="AQP46105"/>
        <property type="gene ID" value="RPIT_09380"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09380"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003953">
        <property type="term" value="F:NAD+ nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019677">
        <property type="term" value="P:NAD catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="SSF52200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="1">
        <location>
            <begin position="17"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="154" mass="16806" checksum="2C15E53E4C751C90" modified="2017-04-12" version="1">MGAVATEAERQAAAHPERRDVFLCHAWGDRQEAAQELHDLLERFGVRVWFSEKDVALGTSLVREIDKGLRMSHIGIVLATPNLLKSLAAEGIADKELSALLATDRVIPVVHGITYEELRDESPLLASRSGLSTGEDTLEQVAVKIANAVRPESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJA1</accession>
    <name>A0A1Q2CJA1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SGNH_hydro domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14495"/>
    <dbReference type="EnsemblBacteria" id="AQP46191">
        <property type="protein sequence ID" value="AQP46191"/>
        <property type="gene ID" value="RPIT_14495"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14495"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH_hydro" evidence="1">
        <location>
            <begin position="27"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="213" mass="23139" checksum="6A7C982EBCBE31B2" modified="2017-04-12" version="1">MARHVEPYRAHWAGLSDGGDGVLRYVALGDSAAQGVGASSVERGYVALLAERLAAESGRRVSVTNLSVSGATSDDVVNDQLPRLAHLPFTPDIVTLDIGGNDVVFPGHNPKTYAASIAVILEALPSGSFVADVPWFSLPFWGRQSRLMSEAAAREAERHGHHLVELHRITREVGLRYHLYTASDLFHPNDVAYEGWADAFWQQMVVSGRVPVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJD3</accession>
    <name>A0A1Q2CJD3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptide ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_14725</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14725"/>
    <dbReference type="EnsemblBacteria" id="AQP46193">
        <property type="protein sequence ID" value="AQP46193"/>
        <property type="gene ID" value="RPIT_14725"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14725"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MetI-like"/>
    </dbReference>
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        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
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        <location>
            <begin position="103"/>
            <end position="129"/>
        </location>
    </feature>
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        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
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        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
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        <location>
            <begin position="280"/>
            <end position="298"/>
        </location>
    </feature>
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        <location>
            <begin position="99"/>
            <end position="298"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP46193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="310" mass="33691" checksum="ED5F025193820DA3" modified="2017-04-12" version="1">MPNDELDAIEHHAVNQDARSLGRDAWEDLRSRPTFWISSFLILVMVLMAAFPDLFTFFAPAQDPAYAQLINARQPPSSEAWFGYDTQGYDIYSRTIHGARASILVGILTTLGTILIGGTIGLLAGFYGGWLDSLLSRVGEVFWSIPLLLGGVLFMTSFPSNVETPYMVVVGKVVLVLTILGWPRIARIMRSAVLQVKSLDYVQSARALGASPLRIILNHVLPNAFTPVIVVATIDLGAYIATEATLSFLGIGLQPPTISWGIAISDASALGMLRAAPHMLLFPSIFLSLTVLAFIMLGDTIRDAFDPKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
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    <dbReference type="Proteomes" id="UP000188324">
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="term" value="P:organic substance biosynthetic process"/>
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        <property type="project" value="UniProt"/>
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    </dbReference>
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    </dbReference>
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            <begin position="15"/>
            <end position="198"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="391" mass="42145" checksum="50D43B95A8B2BB4C" modified="2017-04-12" version="1">MRILMLVATTVATDTRVLREARTLVGAGHEVHIIGRSVPDTFQPDPGITVSSIGTSSVFRPEGGQSLAGRKLSPPMKLARWALLPQHRRSAFGRWADGALADSRGRQFDAVHAHDFTALEAGATLADERGVPLVYDSHELWTGLPREYRPTPLQDRRERRVEQRLGSRADAVITVGDGVAGALRDQYGWDHVTVVRNTFPLNPGKPDVPDEPTGFVYAGRVAAFRELEAIAAASHLVDLPVTIVGPADDTWLGTFDPGRATVLPALPLDEASRLMQANGISLVTHSDRWANHRLAQPNKLFHAVGLGLPVVATDTGELAKVVREHDLGALYPPGDAAGLAGAMRRVVHDFQRYACNVEAAREALSWDADAARLVAVYARLFSGAAGTRGEG</sequence>
</entry>
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    <accession>A0A1Q2CBQ2</accession>
    <name>A0A1Q2CBQ2_9ACTN</name>
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        <submittedName>
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        <submittedName>
            <fullName evidence="2">Probable phosphoglycerate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00760</name>
        <name evidence="2" type="ORF">SAMN05428934_105105</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43530">
        <property type="protein sequence ID" value="AQP43530"/>
        <property type="gene ID" value="RPIT_00760"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86221">
        <property type="protein sequence ID" value="SDY86221"/>
        <property type="gene ID" value="SAMN05428934_105105"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00760"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY86221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="201" mass="22460" checksum="738CF84FE723BE30" modified="2017-04-12" version="1">MTDDDRTQLWIVRHGATEWSESGQHTSVTDLGLLEKGRANAEKVGRRLADVEFGMVLSSPRLRAIQTAELAGFDDVTIDDDLVEWAYGPGEGLTSPEIREQIPGWRIWTHGAPKLDREGYEPGETKEHVAERLGRVVERVRSSGHRRVLAFGHGHAMRALAMVWLDAPVEFAAHFPLQTGTLCVLGYEKENPAIVRWNAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBV1</accession>
    <name>A0A1Q2CBV1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein TonB, links inner and outer membranes</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_01055</name>
        <name evidence="5" type="ORF">SAMN05428934_105162</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01055"/>
    <dbReference type="EnsemblBacteria" id="AQP43581">
        <property type="protein sequence ID" value="AQP43581"/>
        <property type="gene ID" value="RPIT_01055"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87756">
        <property type="protein sequence ID" value="SDY87756"/>
        <property type="gene ID" value="SAMN05428934_105162"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01055"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="SSF141072"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544393" evidence="3">
        <location>
            <begin position="51"/>
            <end position="12360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="48"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="208"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="391"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="562"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="11873"/>
            <end position="11895"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="12275"/>
            <end position="12360"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="109"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="249"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="409"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="12275"/>
            <end position="12311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="12312"/>
            <end position="12338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="12339"/>
            <end position="12353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY87756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="12360" mass="1261249" checksum="BAE63B291665C39E" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBW0</accession>
    <name>A0A1Q2CBW0_9ACTN</name>
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        <submittedName>
            <fullName evidence="3">Sulfide:quinone oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Sulfide:quinone reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01180</name>
        <name evidence="3" type="ORF">SAMN05428934_105185</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY88328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01180"/>
    <dbReference type="EnsemblBacteria" id="AQP43603">
        <property type="protein sequence ID" value="AQP43603"/>
        <property type="gene ID" value="RPIT_01180"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY88328">
        <property type="protein sequence ID" value="SDY88328"/>
        <property type="gene ID" value="SAMN05428934_105185"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01180"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="3"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY88328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="485" mass="52361" checksum="9BD7EBA90097E109" modified="2017-04-12" version="1">MADVLVLGAGVSGHTAALHLSRLLPDGNTVTVVSPNSQWNWIPSNIWVGVGKMKKRQVVFPLVPVYRRKGIRFIQAKATAIWPRGDESAEQPAVDVEFTAPGRTGQTQRLRYDYLVNATGPQLRFHATPGLGPDGGHTVSVCTADHAVEAAQALRATIERLKAGESLTLVVGMGHGTCTCEGAAFEYVFNVDHELREAGVRDRARLVYLTNEAELGDFGVDGMVFEERGFQTTSELWAGSLFRERGVEAILGAHVTRVEPGVVHYETLDGATHTLDFDFGMLLPPFGGVPLQAFDRDGGDITASLFAPSGFMKVDADYTAKPYEEWRADDWPKTYQAVGYDNIWAVGIAFAPPHQISRPRKSANGTVIAPSPPRTGMPSGVMGKVAAMSIADRIRKGPTAPNHEASMAAMGAACVASVGEGLRTGSAAAMTMMPVVPDYQRYDTGRDLADTRGEVGLAGHWVKLMLHHLFLYKAKGLPGWQLIPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBW1</accession>
    <name>A0A1Q2CBW1_9ACTN</name>
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        <submittedName>
            <fullName evidence="5">Anaerobic glycerol-3-phosphate dehydrogenase subunit B</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Glycerol 3-phosphate dehydrogenase (Quinone) subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_01115</name>
        <name evidence="6" type="ORF">SAMN05428934_105174</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY88084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01115"/>
    <dbReference type="EnsemblBacteria" id="AQP43592">
        <property type="protein sequence ID" value="AQP43592"/>
        <property type="gene ID" value="RPIT_01115"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY88084">
        <property type="protein sequence ID" value="SDY88084"/>
        <property type="gene ID" value="SAMN05428934_105174"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01115"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004368">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009158">
        <property type="entry name" value="G3P_DH_GlpB_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000141">
        <property type="entry name" value="Anaerobic_G3P_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03378">
        <property type="entry name" value="glycerol3P_GlpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="4">
        <location>
            <begin position="3"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY88084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="414" mass="41999" checksum="EE5A347CE579B0F4" modified="2017-04-12" version="1">MSDVVVIGAGLAGLVAALRLARAGKSVTLTTKGPGGLHLSQGTVDILGYTPERVSAPLDAVASVPAGHPYASIGAEAVGSAVSWLAEEFGPELLTGDPARNFQFPTAVGALRPTALAQPSMVAGDAVGGKSYAVVGVRQLKDFPADLIAGNLARSKAPDGGALSAHSAWIDLPARKGEADPTPLTYARAMDDQSFAATFAKAVGAVAGKADVVALPAVLGSKRRDVWRQVADQLGRDICEIPLPPPSVPGIRLYDALLAMVRAAGVRFIQGSRIVSFTPGGDGVASVTLAAAGGPRHLKAASFVFAPGGFESGALDVDSFGTITEPVFGLPLTATDAGPLIPSDYWGPHALFEVGVRTDDAGRPIDAAGAVVHTNLFVAGGIIAGCERWREKSGDGIAVATAVRAADHITGGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBX3</accession>
    <name>A0A1Q2CBX3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Lipooligosaccharide transport system ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_01235</name>
        <name evidence="6" type="ORF">SAMN05428934_105196</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY88577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01235"/>
    <dbReference type="EnsemblBacteria" id="AQP43609">
        <property type="protein sequence ID" value="AQP43609"/>
        <property type="gene ID" value="RPIT_01235"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY88577">
        <property type="protein sequence ID" value="SDY88577"/>
        <property type="gene ID" value="SAMN05428934_105196"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01235"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY88577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="308" mass="33999" checksum="73D26E0A77270A4A" modified="2017-04-12" version="1">MPHPVISARALTKRYGDFTAVDGIDFDIAPGESFGFLGPNGAGKSTTMRMIAATSTRTSGELTVLGLDTADHGPEIRAQLGIVPQGDLLDEELRVIDNLIVYGRYFGLPRSYVKQRSEELLDFAQLREKRLSRVSDLSGGMKRRLTIARGLVNNPKVMLLDEPTTGLDPQARHVLWDRLFRLKEEGVTLVVTTHFMDEAEQLCDRLVVIDKGVIVAEGSPSSLIRQYSTREVLEVRFGSARNAAAAGGLDGVGVRREVLPDRILVYADNGEHALQEVLERGFEPLTSLVRRSSLEDVFLRLTGRSLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBY8</accession>
    <name>A0A1Q2CBY8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycosyl hydrolases family 43</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_01325</name>
        <name evidence="10" type="ORF">SAMN05428934_10813</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01325"/>
    <dbReference type="EnsemblBacteria" id="AQP43624">
        <property type="protein sequence ID" value="AQP43624"/>
        <property type="gene ID" value="RPIT_01325"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01146">
        <property type="protein sequence ID" value="SDZ01146"/>
        <property type="gene ID" value="SAMN05428934_10813"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01325"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003343">
        <property type="entry name" value="Big_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011081">
        <property type="entry name" value="Big_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006558">
        <property type="entry name" value="LamG-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02368">
        <property type="entry name" value="Big_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07532">
        <property type="entry name" value="Big_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00635">
        <property type="entry name" value="BID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00560">
        <property type="entry name" value="LamGL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544398" evidence="6">
        <location>
            <begin position="33"/>
            <end position="1377"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="7">
        <location>
            <begin position="98"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="BIG2" evidence="8">
        <location>
            <begin position="835"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="7">
        <location>
            <begin position="986"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1216"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1220"/>
            <end position="1237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP43624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ01146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="1377" mass="147503" checksum="A58635D8738E04AF" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC08</accession>
    <name>A0A1Q2CC08_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_01515</name>
        <name evidence="11" type="ORF">SAMN05428934_10851</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01515"/>
    <dbReference type="EnsemblBacteria" id="AQP43653">
        <property type="protein sequence ID" value="AQP43653"/>
        <property type="gene ID" value="RPIT_01515"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01901">
        <property type="protein sequence ID" value="SDZ01901"/>
        <property type="gene ID" value="SAMN05428934_10851"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01515"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="PTHR43029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="271"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="364"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium_transp" evidence="9">
        <location>
            <begin position="12"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP43653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDZ01901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="442" mass="45654" checksum="3DCA3ACA8D642909" modified="2017-04-12" version="1">MEILEIDTGDTAWVLVSAALVLLMTPGLAFFYGGMVRAKSVLNMLMMSITTMGIVGVLWVVIGYSMAFGNSIGGVVGNPLEFLFLEGLMDPEKATFTIPAAVFAGFQAAFAIIAVALISGAVADRMKFSAWVVFAAVWALVVYFPAAHWVFSFDGGTAERGGFIANQIQALDFAGGTAIHINAGAAALALCLVIGPRLGFGRTPMRPHNLTLVMLGAGLLWFGWFGFNAGSALGANATAGVAWINTLGATAASMLGWLVVERLRDGHATSLGAASGIVAGLVGITPAANSVSPLGGLVIGLLAGVSCAFAIGVKNKLGYDDSLDVVGVHLVGGLVGTLLIGFLADPSSPAGVAGLFYGGGVDQLWRQVLGAGAVLVYSFVVTFVIAKVLDKTMGLRILESAESQGIDVAEHAETGYDLSQVGYTTYGVRQTLIVPVREEASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC38</accession>
    <name>A0A1Q2CC38_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 12">Aspartate-semialdehyde dehydrogenase</fullName>
            <shortName evidence="12">ASA dehydrogenase</shortName>
            <shortName evidence="12">ASADH</shortName>
            <ecNumber evidence="7 12">1.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Aspartate-beta-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">asd</name>
        <name evidence="14" type="ORF">RPIT_01680</name>
        <name evidence="15" type="ORF">SAMN05428934_10885</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1T</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1</strain>
        </source>
    </reference>
    <reference evidence="14" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:24284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.2.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 12">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the aspartate-semialdehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.11" evidence="7 12"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01680"/>
    <dbReference type="EnsemblBacteria" id="AQP43678">
        <property type="protein sequence ID" value="AQP43678"/>
        <property type="gene ID" value="RPIT_01680"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02531">
        <property type="protein sequence ID" value="SDZ02531"/>
        <property type="gene ID" value="SAMN05428934_10885"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01680"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00016"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00463"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004073">
        <property type="term" value="F:aspartate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02121">
        <property type="entry name" value="ASADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000319">
        <property type="entry name" value="Asp-semialdehyde_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012080">
        <property type="entry name" value="Asp_semialdehyde_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005986">
        <property type="entry name" value="Asp_semialdehyde_DH_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01296">
        <property type="entry name" value="asd_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01103">
        <property type="entry name" value="ASD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 12" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="12" id="KW-0521">NADP</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="13">
        <location>
            <begin position="2"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="12">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="9"/>
            <end position="12"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="37"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="157"/>
            <end position="158"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="AQP43678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="SDZ02531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="339" mass="36001" checksum="4D8F23A746D43121" modified="2017-04-12" version="1">MRVGVFGATGQVGEVLRQLLDERNYPVDEIRYFASARSAGKKLPWKDREVVVEDIATADFSGLDVALFSAGGSTSKEWAPKVAAAGATVVDNSSAWRLDDRVPLIVSEVNPEDVDKAELGIIANPNCTTMAAMPVLKALHDAAGLRSMQVTTFQAVSGSGVKGVEALAGQLTQIDDPRVLARDGSAFQVEDTAPYVAPIAYNVVALAGALVDDGEGETDEEKKLRNESRKILHAPDLRVAGTCVRVPVFSGHSLSVHAQFESEITPDQARDILAEAPGVELADVPTPLQAAGADPSFVGRIRQDQSVEGNHGLVLFISNDNLRKGAALNTVQIAELLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC56</accession>
    <name>A0A1Q2CC56_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beta-N-acetylhexosaminidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_01745</name>
        <name evidence="5" type="ORF">SAMN05428934_10897</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01745"/>
    <dbReference type="EnsemblBacteria" id="AQP43689">
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        <property type="gene ID" value="RPIT_01745"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02777">
        <property type="protein sequence ID" value="SDZ02777"/>
        <property type="gene ID" value="SAMN05428934_10897"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01745"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544411" evidence="2">
        <location>
            <begin position="29"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_3" evidence="3">
        <location>
            <begin position="74"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ02777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="404" mass="41365" checksum="3F9AEB699C696351" modified="2017-04-12" version="1">MSRLPWLLAAGALALTGCAPNPEVFESAGESATPAAVEVTGTATHPSMDAVAETSPSPTVTSCRDVASSLSPAEQVGQLFMIGVDTGGLDEATRSAIANARVGSVVLLGNTSAGASPIRQLTAELGSLGSHRVPVLIAVDQEGGTVQRLKGEGFSSIPSAREQGALAEGDLRAAAQQWGEELREVGVHYDLAPVADVVSEAKRGTNEPIGQLNRDYGSDPEAVSQSIVEFVEGMGAASVATSVKHFPGLGEVVTNTDFGIATDDVIEADGESLEPFAAAIDAGVDSVMVSSAVFTKIDPDNEGVFSSVVIEDLLRDDLGFDGVVIADDLGAAKSVSGVAPADRALRFFDAGGDLLINANPSLMATMADATLGRAQSDAEFADRVLDSVERVLRLKSGVGLVDCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC60</accession>
    <name>A0A1Q2CC60_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transport system permease protein PstA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_01760</name>
        <name evidence="10" type="ORF">SAMN05428934_108100</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01760"/>
    <dbReference type="EnsemblBacteria" id="AQP43692">
        <property type="protein sequence ID" value="AQP43692"/>
        <property type="gene ID" value="RPIT_01760"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02840">
        <property type="protein sequence ID" value="SDZ02840"/>
        <property type="gene ID" value="SAMN05428934_108100"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01760"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005672">
        <property type="entry name" value="Phosphate_PstA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00974">
        <property type="entry name" value="3a0107s02c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="8">
        <location>
            <begin position="136"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP43692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ02840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="359" mass="37884" checksum="6EE67818FCEB0352" modified="2017-04-12" version="1">MSIDTTHKPAPSRLNFLTAAQLPKFTPLATLVVSVAAAAGALALFGSASIANVVIFGALLFLVAIFTLSASVEGSRRAKDRLARYVVTGFFLLALTPLISLVWGTVANGISRFDGTFFTWSMRNILGEGGGAVHAIWGTLIITGIATLISVPIGLLTAIYLVEYGSASKLGAGIRFFVDVMTGIPSIVAGLFAYTMFSMIFGAGHKSGLSGAVALTILMIPTVVRSTEEMLRIVPNELREASYALGVPKFRTILKVVLPTSIAGIITGVVLAIARVIGETAPLLVTASFTASMNLDPTQNPMATLPVFVYNQYMYAPGIDTAAYHARAWAGALTLILIVMGLNALGRFIAWKFAPKPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC66</accession>
    <name>A0A1Q2CC66_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dihydroxyacetone kinase DhaK subunit</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Dihydroxyacetone kinase subunit DhaK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01870</name>
        <name evidence="3" type="ORF">SAMN05428934_108122</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ03284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01870"/>
    <dbReference type="EnsemblBacteria" id="AQP43708">
        <property type="protein sequence ID" value="AQP43708"/>
        <property type="gene ID" value="RPIT_01870"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ03284">
        <property type="protein sequence ID" value="SDZ03284"/>
        <property type="gene ID" value="SAMN05428934_108122"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01870"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012736">
        <property type="entry name" value="DhaK_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004006">
        <property type="entry name" value="DhaK_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02733">
        <property type="entry name" value="Dak1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02363">
        <property type="entry name" value="dhaK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51481">
        <property type="entry name" value="DHAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DhaK" evidence="1">
        <location>
            <begin position="7"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ03284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="331" mass="34563" checksum="71915EDED4507C6D" modified="2017-04-12" version="1">MKKLINSADDVLADALKGIEASDGNVRVDHTNRVIYRAEAKDSGKVAIISGGGSGHEPMHGGFVGLGMLDAACCGQVFTSPTPDQMLEATTTVDTGAGVLHIVKNYTGDVMNFEMAAEMAADAGVQVETVLVADDVAVQDSLYTAGRRGVGTTVLLEKIVGAAAEEGQDLASVKAVAQKVADNGRSMGMALTSCTVPSAGKPTFDLPADEMEIGIGIHGEPGRHREPMADAKSIAKQLVDPILHDLDFTGAPVIAMLNGMGGTPLIELYLMYGEVVALLEAAGIKIERNLVGNYITSLDMAGCSLTLVKADDELIRLWDAPVKTAGLRWGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC88</accession>
    <name>A0A1Q2CC88_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aminopeptidase N</fullName>
            <ecNumber evidence="4">3.4.11.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Alanine aminopeptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Lysyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">RPIT_02005</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.</text>
            <dbReference type="EC" id="3.4.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M1 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.2" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02005"/>
    <dbReference type="EnsemblBacteria" id="AQP43733">
        <property type="protein sequence ID" value="AQP43733"/>
        <property type="gene ID" value="RPIT_02005"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02005"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012778">
        <property type="entry name" value="Pept_M1_aminopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="SSF63737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02412">
        <property type="entry name" value="pepN_strep_liv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
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    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M1_N" evidence="15">
        <location>
            <begin position="90"/>
            <end position="190"/>
        </location>
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        <location>
            <begin position="234"/>
            <end position="441"/>
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        <location>
            <begin position="525"/>
            <end position="812"/>
        </location>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
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        </source>
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    </evidence>
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        <source>
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        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00031533"/>
        </source>
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            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF17900"/>
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        <source>
            <dbReference type="EMBL" id="AQP43733.1"/>
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            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
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    <sequence length="834" mass="91639" checksum="B47FC19AB1B1BF5E" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
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    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="96" mass="10850" checksum="B4E7465320788DD9" modified="2017-04-12" version="1">MSSKRRKYTAEFKADAVQLVVVAQRPIAQVARELEINESSLGYWVKIYREQHPDPVKAPPPVEAARLAALEAEVRRLSEENAFLKKAAAFFARTQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCK9</accession>
    <name>A0A1Q2CCK9_9ACTN</name>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02560</name>
        <name evidence="3" type="ORF">SAMN05428934_101112</name>
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    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
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    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
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            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43836.1"/>
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    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02560"/>
    <dbReference type="EnsemblBacteria" id="AQP43836">
        <property type="protein sequence ID" value="AQP43836"/>
        <property type="gene ID" value="RPIT_02560"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY25617">
        <property type="protein sequence ID" value="SDY25617"/>
        <property type="gene ID" value="SAMN05428934_101112"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
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        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <feature type="domain" description="DhaL" evidence="1">
        <location>
            <begin position="6"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY25617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="206" mass="21115" checksum="A27E2CF3BF7AB1BF" modified="2017-04-12" version="1">MADGVMAVTQWLRECAEVFDARADELNKLDRLLGDGDHGTNMARGLAAARELDLTPVAAASDALRHVGMALVSTVGGASGPLFGTFFLRAGANWPRPIQTAGVASAFEAGLAGVMARGNAERGDKTMIDALAPASDALREAALAHISLGEAMDTAAAAAERGRDNTRSMIAKRGRSALLADKSIGVVDPGAVSVAIILRTAANHVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCT8</accession>
    <name>A0A1Q2CCT8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2,3-diaminopropionate biosynthesis protein SbnA</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Cysteine synthase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_03115</name>
        <name evidence="5" type="ORF">SAMN05428934_101224</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY28997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03115"/>
    <dbReference type="EnsemblBacteria" id="AQP43929">
        <property type="protein sequence ID" value="AQP43929"/>
        <property type="gene ID" value="RPIT_03115"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY28997">
        <property type="protein sequence ID" value="SDY28997"/>
        <property type="gene ID" value="SAMN05428934_101224"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03115"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="3">
        <location>
            <begin position="14"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY28997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="336" mass="35478" checksum="A01A451895144CC9" modified="2017-04-12" version="1">MSSARFPASIGADVGSTPLASLERLFRRPDVRVFGKLENRNPTGSAKDRSALGIVREAWESGRLKPGTVVVESSSGNLAMACARLSALLEFSFECVVDPRANARTIAAIEAYGARVHRIAEPDPETGDWLVARLARVRELLGSIPGAITLDQYSNVAAIRAHADGTMREILEQAGEPDLLYVATSTTGTVGGCLRVVGERALRTDVVAVDAEGSVLFGGTRGRRMLSGYGAGFVPPLSQYSSPARVARVDDLSAVIGARALTLTEGLLAGASTGAVISALRADYANLPAGSTVVVMVHDGGMPYLDTVYDDDWVCRTFEVTRAELRARVADFAAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCY6</accession>
    <name>A0A1Q2CCY6_9ACTN</name>
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        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Putative ABC transport system ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_03395</name>
        <name evidence="6" type="ORF">SAMN05428934_101279</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03395"/>
    <dbReference type="EnsemblBacteria" id="AQP43978">
        <property type="protein sequence ID" value="AQP43978"/>
        <property type="gene ID" value="RPIT_03395"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30713">
        <property type="protein sequence ID" value="SDY30713"/>
        <property type="gene ID" value="SAMN05428934_101279"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03395"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY30713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="263" mass="29072" checksum="5C260856133FCD8A" modified="2017-04-12" version="1">MLELDNVTKRFFPGTVNERVALDRVSLTLHEGDFVTVIGSNGAGKSTMLNVISGRYPCDEGRVVIDRKDRTRSPEHRRASQVARVFQDPMAGTAPHLTIEENLAIAFERGGRRGLRMAVTKPKRAVFREALETLELGLEDRLEMRVGMLSGGQRQALSLLMATYAEPAILLLDEHTAALDPARAELITKLTADAVARHNLTTLMVTHNMHQAIELGNRLIMMHEGRIVLEVDEAAKKTITADQLLAEFSKIKGASLADRTLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD23</accession>
    <name>A0A1Q2CD23_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Glutamate-ammonia-ligase adenylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_03510</name>
        <name evidence="6" type="ORF">SAMN05428934_101302</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY31415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03510"/>
    <dbReference type="EnsemblBacteria" id="AQP43996">
        <property type="protein sequence ID" value="AQP43996"/>
        <property type="gene ID" value="RPIT_03510"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY31415">
        <property type="protein sequence ID" value="SDY31415"/>
        <property type="gene ID" value="SAMN05428934_101302"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03510"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008882">
        <property type="term" value="F:[glutamate-ammonia-ligase] adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023057">
        <property type="entry name" value="GlnE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005190">
        <property type="entry name" value="GlnE_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013546">
        <property type="entry name" value="PII_UdlTrfase/GS_AdlTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30621">
        <property type="entry name" value="PTHR30621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08335">
        <property type="entry name" value="GlnD_UR_UTase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03710">
        <property type="entry name" value="GlnE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GlnE" evidence="3">
        <location>
            <begin position="79"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="GlnD_UR_UTase" evidence="4">
        <location>
            <begin position="337"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="GlnE" evidence="3">
        <location>
            <begin position="579"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="domain" description="GlnD_UR_UTase" evidence="4">
        <location>
            <begin position="828"/>
            <end position="969"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY31415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="972" mass="106132" checksum="B9CFE8E6C2801CDC" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD54</accession>
    <name>A0A1Q2CD54_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_03600</name>
        <name evidence="2" type="ORF">SAMN05428934_101321</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY31974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44010">
        <property type="protein sequence ID" value="AQP44010"/>
        <property type="gene ID" value="RPIT_03600"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY31974">
        <property type="protein sequence ID" value="SDY31974"/>
        <property type="gene ID" value="SAMN05428934_101321"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03600"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY31974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="109" mass="11632" checksum="104284478B63AF1D" modified="2017-04-12" version="1">MLKRLGLIAFIVAGLVVAVWGAMSWISPSTSCRGVEMGPGDTCEYSSLTNEKTGEVQRYEDRIAIARQQSPFAVAAGLGMLAFGAVVARSEFRAAVTSVRRPDGPPRTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD57</accession>
    <name>A0A1Q2CD57_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplM</name>
        <name evidence="5" type="ORF">RPIT_03445</name>
        <name evidence="6" type="ORF">SAMN05428934_101289</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY31029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03445"/>
    <dbReference type="EnsemblBacteria" id="AQP43985">
        <property type="protein sequence ID" value="AQP43985"/>
        <property type="gene ID" value="RPIT_03445"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY31029">
        <property type="protein sequence ID" value="SDY31029"/>
        <property type="gene ID" value="SAMN05428934_101289"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03445"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_L13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_L13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_L13_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="PTHR11545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002181">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="SSF52161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY31029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="147" mass="16213" checksum="A1460D18FBB36481" modified="2017-04-12" version="1">MSTYTPKPGEIARNWHVIDADNIVLGRLAAQIATLLRGKHKPSFAPHVDTGDFVVVINASKIALTGNKRADSMRYTHSGRPGGLRAVAIGELLEKDPRRAVERAVWGMLPKNKLSRQMMSKLKVYAGPEHPHAAQKPQTFEITQIAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD59</accession>
    <name>A0A1Q2CD59_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thiamine monophosphate synthase/TENI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_03815</name>
        <name evidence="5" type="ORF">SAMN05428934_101365</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY33209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03815"/>
    <dbReference type="EnsemblBacteria" id="AQP44049">
        <property type="protein sequence ID" value="AQP44049"/>
        <property type="gene ID" value="RPIT_03815"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY33209">
        <property type="protein sequence ID" value="SDY33209"/>
        <property type="gene ID" value="SAMN05428934_101365"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03815"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036206">
        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="SSF51391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TMP-TENI" evidence="3">
        <location>
            <begin position="102"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="213"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY33209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="242" mass="25473" checksum="AFA904EAC1D919C3" modified="2017-04-12" version="1">MTALVGIKTRLRLARLAIVVPPEHSGPESADFAAHGADLLIFTRGDRSVDDAAAAISVARKRLFGLQTVVGTDDSEVAEASLADVLYLRRPGWRPFGYKRPHEHALIGRSIDRAAEADRIDGDPFDFGFIGPAIDGGAVGHEVAELARLYPATALPAGPLWFAAGGITPDNVGQVIAAGARRVVVSTAVFSGSDAFATTRAIADQLAEAWDGDPGARSYGEDAYDSDGPNFPTATLRPRPVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDI0</accession>
    <name>A0A1Q2CDI0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Elongation factor Ts</fullName>
            <shortName evidence="6">EF-Ts</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tsf</name>
        <name evidence="8" type="ORF">RPIT_04500</name>
        <name evidence="9" type="ORF">SAMN05428934_101506</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the EF-Ts family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04500"/>
    <dbReference type="EnsemblBacteria" id="AQP44164">
        <property type="protein sequence ID" value="AQP44164"/>
        <property type="gene ID" value="RPIT_04500"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37053">
        <property type="protein sequence ID" value="SDY37053"/>
        <property type="gene ID" value="SAMN05428934_101506"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04500"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00050">
        <property type="entry name" value="EF_Ts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036402">
        <property type="entry name" value="EF-Ts_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001816">
        <property type="entry name" value="Transl_elong_EFTs/EF1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014039">
        <property type="entry name" value="Transl_elong_EFTs/EF1B_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018101">
        <property type="entry name" value="Transl_elong_Ts_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741">
        <property type="entry name" value="PTHR11741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00889">
        <property type="entry name" value="EF_TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="SSF46934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54713">
        <property type="entry name" value="SSF54713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00116">
        <property type="entry name" value="tsf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01126">
        <property type="entry name" value="EF_TS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF_TS" evidence="7">
        <location>
            <begin position="66"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Involved in Mg(2+) ion dislocation from EF-Tu" evidence="6">
        <location>
            <begin position="75"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY37053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="268" mass="28083" checksum="6BBB97670F8378E2" modified="2017-04-12" version="1">MAITAADVKKLRDATGAGMMDAKKALTEANGDFDQAVEGLRISGLAKQAKRADREATNGIVAGRGGALIQFAAETDFVAKNAEFVGLADEILSAVLESGATDVASTNAATLPSGTTVEDAVKELGAKIGENISVANAANFDGETHLYLHRRAADLPPQVGVLVEYTGDSAAAHQVAMQIAAMSPQYVTREDVPADIVENEKRIAEATAKEEGKPEGAIPRIVEGRVGGFYKDVVLVDQPAVWEDKKTVGDALKASGTEVQRFVRFSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDJ4</accession>
    <name>A0A1Q2CDJ4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">1-deoxy-D-xylulose 5-phosphate reductoisomerase</fullName>
            <shortName evidence="7">DXP reductoisomerase</shortName>
            <ecNumber evidence="7">1.1.1.267</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">1-deoxyxylulose-5-phosphate reductoisomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">2-C-methyl-D-erythritol 4-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dxr</name>
        <name evidence="11" type="ORF">RPIT_04535</name>
        <name evidence="12" type="ORF">SAMN05428934_101513</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:13717"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:58262"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.267"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 1/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DXR family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.267" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04535"/>
    <dbReference type="EnsemblBacteria" id="AQP44171">
        <property type="protein sequence ID" value="AQP44171"/>
        <property type="gene ID" value="RPIT_04535"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37216">
        <property type="protein sequence ID" value="SDY37216"/>
        <property type="gene ID" value="SAMN05428934_101513"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04535"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00092"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030604">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00183">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003821">
        <property type="entry name" value="DXP_reductoisomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013644">
        <property type="entry name" value="DXP_reductoisomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013512">
        <property type="entry name" value="DXP_reductoisomerase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026877">
        <property type="entry name" value="DXPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036169">
        <property type="entry name" value="DXPR_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30525">
        <property type="entry name" value="PTHR30525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08436">
        <property type="entry name" value="DXP_redisom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02670">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13288">
        <property type="entry name" value="DXPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006205">
        <property type="entry name" value="Dxp_reductismrs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69055">
        <property type="entry name" value="SSF69055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00243">
        <property type="entry name" value="Dxr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 7" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0521">NADP</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DXP_reductoisom" evidence="8">
        <location>
            <begin position="4"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="DXP_redisom_C" evidence="9">
        <location>
            <begin position="154"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="DXPR_C" evidence="10">
        <location>
            <begin position="270"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="7"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="184"/>
        </location>
        <ligand>
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        </ligand>
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        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
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        <source>
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    <evidence type="ECO:0000259" key="8">
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            <dbReference type="Pfam" id="PF02670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY37216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="400" mass="42192" checksum="A31A0BE6041E365D" modified="2017-04-12" version="1">MRTIVLLGSTGSIGTQTLDVISSRRDQFRVTGLSASGGNLELLARQIIEFKPDVVALARASAAQELQRLLYAEADRHEWNQGGYQLPKLLLGPDASTTLAAQGADVVVNAITGAAGLGPTLAALKAGSTLALANKESLVIGGRLVTQAAAPGQIVAVDSEHSAFAQALRCGRADEVRRLILTASGGPFRGKTGEELVDVTPQQAMAHPTWDMGRVITINSSTLVNKGLELIEAALLYDVDFDDIVVTVHPQSIVHSMVEFHDGSTIAQASPPDMRLPIGIALTWPERLADAAQPCDWSTASSWTFEPLDSETFPAVEIARVAGKAAGTAPAVYNAANEACVDAFWEGRIGFLDITRIVGQCVDEHLDRGHVTDDSLTVDDVLAADAWGRARAAEICGVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDL0</accession>
    <name>A0A1Q2CDL0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">ABC-2 type transport system ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_04330</name>
        <name evidence="6" type="ORF">SAMN05428934_101471</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
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        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04330"/>
    <dbReference type="EnsemblBacteria" id="AQP44135">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY36175">
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        <property type="gene ID" value="SAMN05428934_101471"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
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    </dbReference>
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        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
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        <property type="entry name" value="ABC_transporter-like_CS"/>
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        <property type="entry name" value="ABC_tran"/>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="5"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
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        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY36175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="233" mass="24546" checksum="8E17CC9B8BBFDB7D" modified="2017-04-12" version="1">METVVDAQDLSLAFGATKALDGLTLSASAGAVTALLGPNGAGKTTFIRCCTALERPHSGSLTLFGQSPGSPDVLSRIGLMPQATGAWSGIRAEELLRYLSRLYADPQPVEALVDLLGIAPFARTPYRRLSGGQQQAVNLAGALIGRPSLVFLDEPSAGLDPRARRLTWDVVRRVRDAGVAVVLTTHDMVEAAELADHVHIVDRGRVQVSGSVSDLASHGSLEDAFLTHTSGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDM6</accession>
    <name>A0A1Q2CDM6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04775</name>
        <name evidence="3" type="ORF">SAMN05428934_101564</name>
    </gene>
    <organism evidence="2 4">
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        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44214">
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        <property type="gene ID" value="RPIT_04775"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY38470"/>
        <property type="gene ID" value="SAMN05428934_101564"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04775"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY38470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="98" mass="10053" checksum="7C88021C890768D0" modified="2017-04-12" version="1">MNTVWLALEGAGNVLLAGLVLGAGLPAIFAMGIRALSWGSGTMVNTEDHSPHLVGRVVGYACFAIVVVAILLGVGVIVASGMGMRLSFDSVIPMFVPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDN4</accession>
    <name>A0A1Q2CDN4_9ACTN</name>
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        <submittedName>
            <fullName evidence="3">Protoporphyrinogen oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04760</name>
        <name evidence="3" type="ORF">SAMN05428934_101561</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY38391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04760"/>
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        <property type="protein sequence ID" value="AQP44211"/>
        <property type="gene ID" value="RPIT_04760"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY38391">
        <property type="protein sequence ID" value="SDY38391"/>
        <property type="gene ID" value="SAMN05428934_101561"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04760"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY38391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="409" mass="42804" checksum="523AA62FDFEDFE60" modified="2017-04-12" version="1">MDADVVIIGAGVAGLNAARVVKRSGATPVVLESSQEIGGRVRTELVDGFKVDVGFQVLNPGYPALRKAVDLGELGLRSFGRGVCARTDGRLVEIMDPSRAPWRGAAARLAARDPRAVGRLALWLGDRAGADVTLSESLDKAKVHGFWRSLLEGFLAGVIGDDSGSTSASFTRGLVGWFLLGTPGLPAQGMAALPARLAERSGAQVRRGVRVTSVSPEGSGWVVKTDGDTWRARSVIIATDPWTAVALAGGPSPAPARGLATWWFDAPVAPTRSNLLHLEVDRRGPVVNTAVVSNAQPSYAPAGRHLVQASTLWREDRQPTESEVRRHAEAIYGSSTADWRVVAAHVVRDALTPVLPGREAPTIEAGPGLYVATDAGEASLQGALRRGAAAGERAAAWTGANQGPEPVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDN8</accession>
    <name>A0A1Q2CDN8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized conserved protein YndB, AHSA1/START domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04850</name>
        <name evidence="3" type="ORF">SAMN05428934_101578</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
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        <property type="protein sequence ID" value="AQP44224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY38819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44224">
        <property type="protein sequence ID" value="AQP44224"/>
        <property type="gene ID" value="RPIT_04850"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY38819">
        <property type="protein sequence ID" value="SDY38819"/>
        <property type="gene ID" value="SAMN05428934_101578"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04850"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="Activator_of_Hsp90_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY38819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="140" mass="15707" checksum="6EA3F1C6D4841378" modified="2017-04-12" version="1">MSERIEISTIVDAPIEAAWAAFTDEDAIQAWNHASDDWHCPLASNDLREGGEFSYTMEEVDGDESFEFAGTYTTVVDHRLIEYTLDDGRSVSVTFETQADGTTLVQQSFDPDEEEPTDPQRAGWQAILDNFAEYAEKDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDR2</accession>
    <name>A0A1Q2CDR2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5709 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_04990</name>
        <name evidence="4" type="ORF">SAMN05428934_101604</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY39496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04990"/>
    <dbReference type="EnsemblBacteria" id="AQP44248">
        <property type="protein sequence ID" value="AQP44248"/>
        <property type="gene ID" value="RPIT_04990"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY39496">
        <property type="protein sequence ID" value="SDY39496"/>
        <property type="gene ID" value="SAMN05428934_101604"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043763">
        <property type="entry name" value="DUF5709"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18970">
        <property type="entry name" value="DUF5709"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5709" evidence="2">
        <location>
            <begin position="89"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY39496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="143" mass="15536" checksum="6AA3881B7F040BA1" modified="2017-04-12" version="1">MDDITGETLPDESEQLDQLQPGDSLIDRGVDDVLDEGYIAPDQWSPAQGFGNTPAEMRQGETLEMRMKQETPEKVEDPQDWNPSKESRQVGAVRAGRLMAVQGADGEQHTLGIDVGYGGGAASAEEAAMHVISDDEDDDFLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDY6</accession>
    <name>A0A1Q2CDY6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05530"/>
    <dbReference type="EnsemblBacteria" id="AQP44342">
        <property type="protein sequence ID" value="AQP44342"/>
        <property type="gene ID" value="RPIT_05530"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05530"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021421">
        <property type="entry name" value="DUF3071"/>
    </dbReference>
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        <property type="entry name" value="DUF3071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="320" mass="35187" checksum="3DF4C7EF91617F4E" modified="2017-04-12" version="1">MVNALTPREIQARIRSGSSVDDVVAETGMSTERIEAFAGPVLAEREHIASAAQSATIRRRGEAGSHHRLREIIAERLSSRGIDSDAIEWDAWRQNDLKWRVVGRLGEGDDARTAEFIFDPKGRFSVAHNGDARWLIGEEPPGAAPEEENTVDFSDELALVRATHETQPDDQPGDDVPSSALMHDSNEDTSQLDRLYDMLSGISEDSVRIYTGIMSPAEPLPDDQTTPVEPPRRQPRSPPPPPRSLHRPRSPVPRMSPPRSPWSTPAPPFPSRARRSAARRCPPGTRSCSVGPTPSSLAPCLRPVGREQVARDKGRPPQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE33</accession>
    <name>A0A1Q2CE33_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GlcNAc-PI de-N-acetylase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">N-acetylglucosaminyl deacetylase, LmbE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05790</name>
        <name evidence="3" type="ORF">SAMN05428934_103105</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44384">
        <property type="protein sequence ID" value="AQP44384"/>
        <property type="gene ID" value="RPIT_05790"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67827">
        <property type="protein sequence ID" value="SDY67827"/>
        <property type="gene ID" value="SAMN05428934_103105"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05790"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016137">
        <property type="term" value="P:glycoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="PTHR12993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY67827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="243" mass="26457" checksum="9A085A8F47E63B1A" modified="2017-04-12" version="1">MAPDIQPLSDDQFQRILIVVAHPDDVEYGMSACVHKWVARGATVAYLLLTSGEAGMQRPPAEVGPLRAAEQREACRRVGVDDLTILDHPDGVLEYSLALRRDVARRIREFRPDTVATSAFDVEVGWGLNQADHRVAGLVALDACRDADNTWVFPELAEEGLEKWGTRRFLVFGDPNPSHGVVLTREDVDAGIASLTAHEAYLADLPGHPAPEQFLTEGLSAQGEAMGVEFAALFRVHELAGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE57</accession>
    <name>A0A1Q2CE57_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05785</name>
        <name evidence="3" type="ORF">SAMN05428934_103104</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44383">
        <property type="protein sequence ID" value="AQP44383"/>
        <property type="gene ID" value="RPIT_05785"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67800">
        <property type="protein sequence ID" value="SDY67800"/>
        <property type="gene ID" value="SAMN05428934_103104"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05785"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009282">
        <property type="entry name" value="DUF937"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06078">
        <property type="entry name" value="DUF937"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY67800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="231" mass="24041" checksum="B5292EDCD5487F30" modified="2017-04-12" version="1">MYDYNELLNSLPIDQLASRVGESPAEVESAVRNALPTLLMGMGANAQDPAGEASLRSALSQHDPSLVQGGVDLGRVDPEDGRKITHHIFGSNEDQVINQLGGLGGGNALIQKLLPILAPIVMSWLAGKLMGRDEAQSQTQQAPGGGGLGDILGQILGGGQAAPQQQAPRAQQPKFRTPDFSDQGGAEPQMRMPEPDAPRAQPRQDQQAADNPLGGGVLGQILGGLLGGGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE61</accession>
    <name>A0A1Q2CE61_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Death on curing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05925</name>
        <name evidence="3" type="ORF">SAMN05428934_103132</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05925"/>
    <dbReference type="EnsemblBacteria" id="AQP44409">
        <property type="protein sequence ID" value="AQP44409"/>
        <property type="gene ID" value="RPIT_05925"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68525">
        <property type="protein sequence ID" value="SDY68525"/>
        <property type="gene ID" value="SAMN05428934_103132"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05925"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006440">
        <property type="entry name" value="Doc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39426">
        <property type="entry name" value="PTHR39426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01550">
        <property type="entry name" value="DOC_P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="1">
        <location>
            <begin position="5"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY68525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="124" mass="13619" checksum="748BDED6A4F4C2FA" modified="2017-04-12" version="1">MTEYLTLEDLLLLIDDLGVGPVRDVGLLESAAHRPTSSLWGTDAYPDISVKAAAIMESLVRNYALIDGNKRLGWLAAIVFLDINGLEVDAPDDDAYDLVIAVASGQADLREIADALRRWSHERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE94</accession>
    <name>A0A1Q2CE94_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">O-acetylhomoserine (Thiol)-lyase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">O-acetylhomoserine aminocarboxypropyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_06020</name>
        <name evidence="6" type="ORF">SAMN05428934_103150</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06020"/>
    <dbReference type="EnsemblBacteria" id="AQP44423">
        <property type="protein sequence ID" value="AQP44423"/>
        <property type="gene ID" value="RPIT_06020"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68965">
        <property type="protein sequence ID" value="SDY68965"/>
        <property type="gene ID" value="SAMN05428934_103150"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:pyridoxal phosphate binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006235">
        <property type="entry name" value="OAc-hSer/O-AcSer_sulfhydrylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
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        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="OAH_OAS_sulfhy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY68965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="426" mass="45326" checksum="35E85E6034FA503D" modified="2017-04-12" version="1">MNYRPETLAVHAGQETADPATNSRAVPIYQTTSYVFDDAQHAADLFALRTPGNIYTRIMNPTQSVLETRVNALEGGVGALATASGASAVTYSVLNLTYAGDNIVALSTLYGGTYALFAHTLAQFGIEARFVDPSKPEDLAKHVDEKTKLVFGETVGNPALNVIDLDAWSAAAHELGLPFILDNTVPTPVLTRAFDHGVDVVVHAATKYLGGHGTSLGGVIVDSGNFDWAAHSERFPGLTKPDDAYHGVVWTEAAGPAAYIIRARTVLLRNTGAAIAPMNSFLLLQGIETLHLRMERHSENAAKVAQFLVDHPKVTWVNYPGLESSPSHEIAKRILKGGFGGLVSFGVDGGRDAGQKVVESFELFSHLANIGDVKSLAIHNASTTHSQLGEDELAAAGVPAEMVRLSVGIENIDDILADLSQALDQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CED5</accession>
    <name>A0A1Q2CED5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycerophosphoryl diester phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05970</name>
        <name evidence="3" type="ORF">SAMN05428934_103140</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05970"/>
    <dbReference type="EnsemblBacteria" id="AQP44415">
        <property type="protein sequence ID" value="AQP44415"/>
        <property type="gene ID" value="RPIT_05970"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68726">
        <property type="protein sequence ID" value="SDY68726"/>
        <property type="gene ID" value="SAMN05428934_103140"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05970"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GP-PDE" evidence="1">
        <location>
            <begin position="13"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY68726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="256" mass="28458" checksum="8BB9BDC17F9840E5" modified="2017-04-12" version="1">MAGVHDDYLSPEFIPMAHRGGALLTANLGIENTLRAFSAAVDLGYRYLETDVHVTADGALVAFHDEDLHRVTDVTGSISEFSLEEIRQLRVGEREPIPTVDELLETFPHINFNIDIKGDAAVRPLDEALRRHGAERRVCVGSFSRSRIRLFRALQPRVPTAVSPSGVMAMRAGMFRTAGKVFQVPLSHQVGPVTVDLVTPRSIARIHAAGMKIHVWTIDDPTTMHRLIDWGVDGIITDRPDLLKEVLRARGMWSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEE5</accession>
    <name>A0A1Q2CEE5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Preprotein translocase subunit YajC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_06315</name>
        <name evidence="11" type="ORF">SAMN05428934_103208</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YajC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06315"/>
    <dbReference type="EnsemblBacteria" id="AQP44473">
        <property type="protein sequence ID" value="AQP44473"/>
        <property type="gene ID" value="RPIT_06315"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70470">
        <property type="protein sequence ID" value="SDY70470"/>
        <property type="gene ID" value="SAMN05428934_103208"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06315"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003849">
        <property type="entry name" value="Preprotein_translocase_YajC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33909">
        <property type="entry name" value="PTHR33909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02699">
        <property type="entry name" value="YajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01853">
        <property type="entry name" value="YAJCTRNLCASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01323">
        <property type="entry name" value="YajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00739">
        <property type="entry name" value="yajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="84"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="99"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY70470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="138" mass="15492" checksum="8E47824CFC964ADA" modified="2017-04-12" version="1">MLEMLLMMAALFAVMYFLLIRPQKKRMEQHQQMQAALQPGERVLLTSGIFATIVHTGEKQLIVELAPGLEVTVLKGNVAQRVTPDDEEFEFTEDTVPASSVEDAPQTTDGDFSGQFDDLRPEDFQRPDTPDDHRAGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEE6</accession>
    <name>A0A1Q2CEE6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Adenine phosphoribosyltransferase</fullName>
            <shortName evidence="10">APRT</shortName>
            <ecNumber evidence="5 10">2.4.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">apt</name>
        <name evidence="12" type="ORF">RPIT_06300</name>
        <name evidence="13" type="ORF">SAMN05428934_103205</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:16609"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.4.2.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.7" evidence="5 10"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06300"/>
    <dbReference type="EnsemblBacteria" id="AQP44471">
        <property type="protein sequence ID" value="AQP44471"/>
        <property type="gene ID" value="RPIT_06300"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70384">
        <property type="protein sequence ID" value="SDY70384"/>
        <property type="gene ID" value="SAMN05428934_103205"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06300"/>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00646"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003999">
        <property type="term" value="F:adenine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006168">
        <property type="term" value="P:adenine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00004">
        <property type="entry name" value="Aden_phosphoribosyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005764">
        <property type="entry name" value="Ade_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01090">
        <property type="entry name" value="apt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="11">
        <location>
            <begin position="47"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP44471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY70384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="180" mass="18980" checksum="ED1F605542B6E537" modified="2017-04-12" version="1">MSEAAYRRELVGSLIHDVPDFPKPGVVFKDITPLLASPHGFQAAVTELVTTAPRQIDIVVGMEARGFIFAAPVALALGAGFVPVRKPGKLPGETISESFELEYGFETLTMHRNAIPADARVLVVDDVLATGGTVGATAALLQQMGAELVHVSVVMELGFLGGRARLAEQGIDNFSAILTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEG9</accession>
    <name>A0A1Q2CEG9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06590</name>
        <name evidence="3" type="ORF">SAMN05428934_103263</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06590"/>
    <dbReference type="EnsemblBacteria" id="AQP44519">
        <property type="protein sequence ID" value="AQP44519"/>
        <property type="gene ID" value="RPIT_06590"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71962">
        <property type="protein sequence ID" value="SDY71962"/>
        <property type="gene ID" value="SAMN05428934_103263"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06590"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="29"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY71962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="301" mass="31732" checksum="4E2CB5B92DA28996" modified="2017-04-12" version="1">MERMTDANFSRPGAVDLSSLAQPTPAAGSSFVLQVTEAEFQDVASRSVQYPVIVEFHSPRDPSGAAVSAALTELVNAAGGKFLLARVDVDAEVRVAQALGVQAVPTVIALIGGQMAPLFQGTKSRDEIAALLDQVAQLAVANGMTGRAQPVGAAASQEATDAPAANPRFAKADAALEAGDYAAAVREFDALLAETPNDPEVLAGRAQSALLERSLSFDPDAIVRRANADDTDVEAALDAADLEIIAGRYQEAFDRLLELAGRVGPDQRDPIRLRMLELFEVVGRTDPAVLKARRRLSSVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEJ2</accession>
    <name>A0A1Q2CEJ2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Malto-oligosyltrehalose synthase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Maltooligosyl trehalose synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06580</name>
        <name evidence="3" type="ORF">SAMN05428934_103261</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06580"/>
    <dbReference type="EnsemblBacteria" id="AQP44517">
        <property type="protein sequence ID" value="AQP44517"/>
        <property type="gene ID" value="RPIT_06580"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71907">
        <property type="protein sequence ID" value="SDY71907"/>
        <property type="gene ID" value="SAMN05428934_103261"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06580"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11336">
        <property type="entry name" value="AmyAc_MTSase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012767">
        <property type="entry name" value="Trehalose_TreY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02401">
        <property type="entry name" value="trehalose_TreY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="1">
        <location>
            <begin position="2"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY71907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="840" mass="92038" checksum="EA91EF409649E105" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEK7</accession>
    <name>A0A1Q2CEK7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cysteine desulfurase</fullName>
            <ecNumber evidence="4">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_06540</name>
        <name evidence="10" type="ORF">SAMN05428934_103253</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06540"/>
    <dbReference type="EnsemblBacteria" id="AQP44510">
        <property type="protein sequence ID" value="AQP44510"/>
        <property type="gene ID" value="RPIT_06540"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71687">
        <property type="protein sequence ID" value="SDY71687"/>
        <property type="gene ID" value="SAMN05428934_103253"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06540"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010240">
        <property type="entry name" value="Cys_deSase_IscS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="PTHR11601:SF34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="8">
        <location>
            <begin position="6"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY71687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="370" mass="37387" checksum="6A362911EED8BDFF" modified="2017-04-12" version="1">MNARGYFDHAATTPLRPEALDELVRLASLVGNPSALHRSGQLARRALEEAREELAEAVGAHPTEVIFTSGGSEADSIAVLGGWAARRAERPGCLVSAVEHPAVVGAVKRGAGILPVTAEGVVDLDAADRLIDAGTGIVSVMAVGNETGTVQPAAAVAALAAGAGAWFHTDAVQALGHIPLDFATSGAHLMSLSAHKVGGPVGVGALLCRREVQPAPIGLGGGQERGLRSGTVPVALAASFARAASVAVAGQAAEAVRLAGLRDRVADLCLRLGGRLNSLPGGAPHIVNVTFDGVRADDLLFLLDQAGIRASVGSACRAGVHQPSEVLLAMGRTLDEATQSLRFSLGWTTTDDDVEALGGALAAGLQIATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEM8</accession>
    <name>A0A1Q2CEM8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_06900</name>
        <name evidence="2" type="ORF">SAMN05428934_11066</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06900"/>
    <dbReference type="EnsemblBacteria" id="AQP44574">
        <property type="protein sequence ID" value="AQP44574"/>
        <property type="gene ID" value="RPIT_06900"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09441">
        <property type="protein sequence ID" value="SDZ09441"/>
        <property type="gene ID" value="SAMN05428934_11066"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06900"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ09441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="170" mass="18488" checksum="825CBF250EE32CDE" modified="2017-04-12" version="1">MADRLLACLMDVERHVSSAGWDQPARLFALVTTSTLLEVEPQLRGRVPETSPDALTAIEQDEFHATDDVVERLSGIFWPDTVEGCAIAMERAFLPPEHEADLPDDPILAAEFVAKHPAKSDVRVVVGVLRDGAKHGLARLLSNPDDLLGGEDLVPGLADALLDTFRSEDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEP6</accession>
    <name>A0A1Q2CEP6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endonuclease NucS</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nucS</name>
        <name evidence="3" type="ORF">RPIT_06620</name>
        <name evidence="4" type="ORF">SAMN05428934_103270</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NucS endonuclease family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY72169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06620"/>
    <dbReference type="EnsemblBacteria" id="AQP44525">
        <property type="protein sequence ID" value="AQP44525"/>
        <property type="gene ID" value="RPIT_06620"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY72169">
        <property type="protein sequence ID" value="SDY72169"/>
        <property type="gene ID" value="SAMN05428934_103270"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06620"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00722">
        <property type="entry name" value="NucS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002793">
        <property type="entry name" value="Endonuclease_NucS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38814">
        <property type="entry name" value="PTHR38814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01939">
        <property type="entry name" value="NucS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY72169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="230" mass="25209" checksum="4E6E2C50B1C9A585" modified="2017-04-12" version="1">MRLVIARCQVDYVGRLTAHLPMATRLILVKADGSVSIHADDRAYKPLNWMSPPCTLSVTPPDPEAAEALGVTEVWQVRSRDGDTLHISVADVIHDSAHELGVDPGLQKDGVEAHLQALLAEHPAALGDGLKLVQREYLTPIGPVDLLLRDGEGYVAVEVKRRGEIDGVEQLTRYLDLMNRDPQLAPVRGVFAAQQIKPQARTLASDRGIACRTIDYDALRGLDNADERLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CES9</accession>
    <name>A0A1Q2CES9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cell division protein FtsK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">RPIT_07120</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homohexamer. Forms a ring that surrounds DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FtsK/SpoIIIE/SftA family.</text>
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        <property type="component" value="Chromosome"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
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        <property type="entry name" value="FtsK_4TM"/>
    </dbReference>
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        <property type="entry name" value="FtsK_alpha"/>
    </dbReference>
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        <property type="entry name" value="FtsK_dom"/>
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        <property type="entry name" value="Ftsk_gamma"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FtsK_gamma"/>
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    </dbReference>
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        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="101"/>
            <end position="119"/>
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    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
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            <end position="338"/>
        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="11">
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            <begin position="1"/>
            <end position="28"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="11">
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            <end position="49"/>
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        <location>
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            <end position="507"/>
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        <source>
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            <dbReference type="SAM" id="Phobius"/>
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        <source>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
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    <sequence length="833" mass="89096" checksum="7F890E78AAE4E3AE" modified="2017-04-12" version="1"> </sequence>
</entry>
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        </source>
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            </authorList>
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        </source>
    </reference>
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        </location>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ08286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
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            <dbReference type="PubMed" id="26869509"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
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    </dbReference>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ18323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="199" mass="22078" checksum="E29A3C65621018A5" modified="2017-04-12" version="1">MTQEQPYDVLSSFRDFEVRRYPAHLVAEVGVDASFTRAGNEAFGVLVAYISGRNSTRGKVAMTAPVLQEQASAAIEMTSPVVQQPGGKSGRHVVAFVMPAEFTLDTLPTPADPRINVREVPAHVAAVRSFTGRWTEHVYELQLNELRGAVEQAGLEVSGPPLFARFDPPWTPWFRRRNEVVLPVGWNPPTRRDAKTTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEW3</accession>
    <name>A0A1Q2CEW3_9ACTN</name>
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    <organism evidence="1 3">
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    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000014">
        <property type="protein sequence ID" value="SDZ18621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44659">
        <property type="protein sequence ID" value="AQP44659"/>
        <property type="gene ID" value="RPIT_07425"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ18621">
        <property type="protein sequence ID" value="SDZ18621"/>
        <property type="gene ID" value="SAMN05428934_11442"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07425"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012551">
        <property type="entry name" value="DUF1707"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08044">
        <property type="entry name" value="DUF1707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ18621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="209" mass="22829" checksum="C8DF20C82D6C9E9D" modified="2017-04-12" version="1">MDFRDLPDGRLRVTAQQRDHAAAILREAVVDGRLTVEELNARLPTALNAFAREDIYRILDDLVPAAALPAVVAEQGPMGDGPGMRWENPLLIRSTWAGHHQEGTWDLPPFVEIIGTGWGGVKLDCTRARPLARVIDIVITGNPSVNLIVPDGWGVDVQQLNVSGQSGTINSMVPTRPIGDLPRLILRGSTTMAVKVRQPRRRERAITSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEW8</accession>
    <name>A0A1Q2CEW8_9ACTN</name>
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        <submittedName>
            <fullName evidence="4">ISL3 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_07450</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44664">
        <property type="protein sequence ID" value="AQP44664"/>
        <property type="gene ID" value="RPIT_07450"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07450"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002560">
        <property type="entry name" value="Transposase_DDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032877">
        <property type="entry name" value="Transposase_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029261">
        <property type="entry name" value="Transposase_Znf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01610">
        <property type="entry name" value="DDE_Tnp_ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13542">
        <property type="entry name" value="HTH_Tnp_ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14690">
        <property type="entry name" value="zf-ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-ISL3" evidence="3">
        <location>
            <begin position="23"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_Tnp_ISL3" evidence="2">
        <location>
            <begin position="78"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_ISL3" evidence="1">
        <location>
            <begin position="165"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="415" mass="46745" checksum="008235805E1B3B7A" modified="2017-04-12" version="1">MVGVQRDDAGLRVEVESRPPAVMGCPACGVIAHAHGRQRVELIDAPCFTAPVKLRWRKRRWLCPEPMCPVTSFMEQDPYVARPRALLTARATSWAIGQMRRENASVQGMARQLGCTWRTLWRAVKPILETAAADETRFVGVTSLGVDEHIWHHVSTKPVDQGGRGPKEFTGMVDLTRDKDGRVRARLLDLVPGRSGEAYTSWLRDRGDTFRKGVEIATLDPFHGYKNAIDDQLDDAIAVLDAFHVVKLGTAAVDEVRRRVQQDIHGHRGRRDDPLYRIRNLLRAGKEHLTDRQKTRLETAFTADDRHVEVEVAWRCAQQLRSVYHQSCHADGRRVAEKILATFPSCPIPEIARLGRTLNQWRDAFLGYFTTGGANNGGTESINGLIELARRVARGFRDPDNYRLRMLLIGGGLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEY5</accession>
    <name>A0A1Q2CEY5_9ACTN</name>
    <protein>
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        </submittedName>
        <submittedName>
            <fullName evidence="4">Redoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_07250</name>
        <name evidence="5" type="ORF">SAMN05428934_1147</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000014">
        <property type="protein sequence ID" value="SDZ17888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07250"/>
    <dbReference type="EnsemblBacteria" id="AQP44630">
        <property type="protein sequence ID" value="AQP44630"/>
        <property type="gene ID" value="RPIT_07250"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ17888">
        <property type="protein sequence ID" value="SDZ17888"/>
        <property type="gene ID" value="SAMN05428934_1147"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07250"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="59"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ17888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="206" mass="22688" checksum="FAF542608DB03D41" modified="2017-04-12" version="1">MTTTNPAPSRREQLKARQEAETRRDTKRRTWSRIIGGVVTLIVVVVVGYGLWTAIPEQGDTQRVAPDFTLTTTAGATVTLSDLRPSPVLIYFNEGAGCASCTMQMAEIEKNPGFAEAGIQVLPIVMNSAEQILPDMQQFGVTTPYLLDDGTVSKAYDVLDKGMHPGMPGHGFVLIDGEGVQRWYGNYPSMWLDPQELLDEVTTRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEZ3</accession>
    <name>A0A1Q2CEZ3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07315</name>
        <name evidence="3" type="ORF">SAMN05428934_11420</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ18138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44640">
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        <property type="gene ID" value="RPIT_07315"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ18138">
        <property type="protein sequence ID" value="SDZ18138"/>
        <property type="gene ID" value="SAMN05428934_11420"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07315"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ18138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="84" mass="8739" checksum="5DF3876B3E4C18F3" modified="2017-04-12" version="1">MSLHSQHRPTDTGPDTPPAATGPAQQHQGHGGHMWHMLLMCLPLIGFGLWSLFSGGGAGALIGGLLCAGMMLLMHGRPGAGHRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF42</accession>
    <name>A0A1Q2CF42_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS110 family transposase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transposase IS116/IS110/IS902 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07515</name>
        <name evidence="3" type="ORF">SAMN05428934_1191</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000019">
        <property type="protein sequence ID" value="SDZ21803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44675">
        <property type="protein sequence ID" value="AQP44675"/>
        <property type="gene ID" value="RPIT_07515"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ21803">
        <property type="protein sequence ID" value="SDZ21803"/>
        <property type="gene ID" value="SAMN05428934_1191"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07515"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="1">
        <location>
            <begin position="10"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ21803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="398" mass="42499" checksum="22A17DCA48AD1136" modified="2017-04-12" version="1">MDQDRFDVFVGLDVGKEHHHATALNSAGRRLHDKALPQDEAALREVFDKLTVHGSVLVIVDQPATIGALPVTVARAMGIEVAYLPGLAMRRIADLHPGNAKTDARDAFIIAEAGRTMPHALRRVGGDDDLIADLAVIVGFDDDLASEVNRVSNRIRGMLTQIHPALERAIGANIGHPAVLALLAKFAGPTGLAAAGRRRLTTTTKPLAPRMHTRLVDAIIKALTEQTVVVPGTRAAELVLPQLAAQLQGLLAQRAAAAKQVEEALDAHPLSQLLMSMPGVGIRTAARLLLDVGDATAFPTAGHLAAYAGLAPVTRRSGSSIRGEHPSRAGNKHLKRALFLSAFAALHDPDSRAYYDRKRAAGKKHNAAIICLARRRVDVLHAMLRNGTYYQPRPAVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF45</accession>
    <name>A0A1Q2CF45_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44736">
        <property type="protein sequence ID" value="AQP44736"/>
        <property type="gene ID" value="RPIT_07890"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07890"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="111" mass="11961" checksum="30A3AE92777E0FAF" modified="2017-04-12" version="1">MGPGVMEILQLVFGVALVIVLALVLRVLIVRAFGLRLTDWIGYVACAAGVVAIPSIQWDISPWLLLGVPVALALALWKGKSTVDAWRRGEPVEGIFTFSPPPPGVVDRFRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFA0</accession>
    <name>A0A1Q2CFA0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_08315</name>
        <name evidence="2" type="ORF">SAMN05428934_11512</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08315"/>
    <dbReference type="EnsemblBacteria" id="AQP44802">
        <property type="protein sequence ID" value="AQP44802"/>
        <property type="gene ID" value="RPIT_08315"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19246">
        <property type="protein sequence ID" value="SDZ19246"/>
        <property type="gene ID" value="SAMN05428934_11512"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08315"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022292">
        <property type="entry name" value="CHP03843"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03843">
        <property type="entry name" value="TIGR03843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ19246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="240" mass="25797" checksum="517B61B145EBA9F4" modified="2017-04-12" version="1">MKLTLVGRLVDASNGTFLASDEDESLWVYKPVAGEAPLWDFPEATLGRREVAAHALSEHLGLGIVPLTVWADGPLGEGSVQAWVEGEPTDTIALLRPERIDENWLPILAAEDEDGAPVVLAHSDDGRLRTVAVFDALLNNSDRKASHLIAAGAKLFGVDHGVSMHVDDKLRTVLWGWAGDPLSDAELALCSDVASLTAPLAPGLDDDEWEALRRRAKALLEAGTMPMPSGRWPGIPWPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFE0</accession>
    <name>A0A1Q2CFE0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ADP-ribose pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08075</name>
        <name evidence="3" type="ORF">SAMN05428934_11355</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ17057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08075"/>
    <dbReference type="EnsemblBacteria" id="AQP44765">
        <property type="protein sequence ID" value="AQP44765"/>
        <property type="gene ID" value="RPIT_08075"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ17057">
        <property type="protein sequence ID" value="SDZ17057"/>
        <property type="gene ID" value="SAMN05428934_11355"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08075"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="44"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ17057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="206" mass="23040" checksum="4EFFB105F8593F78" modified="2017-04-12" version="1">MRGDELMSWPVRSRTVLGEGRISAFVDEEVETPSGEVMTRQYLTHPGAVAVVAWREDTDEVAVLRQYRHPVRMELVELPAGLLDNDGEDWCLAAQRELAEEVELMAERWDVLVDTCTTPGACEESLRIYLARDIAPAARPEGFVLEDEEAHMSWSWVPRAQLVDAVLDGAVQNPSLVSGILALEVARVHGRLDSLRPATADWPIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFE7</accession>
    <name>A0A1Q2CFE7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_08250</name>
        <name evidence="2" type="ORF">SAMN05428934_11525</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08250"/>
    <dbReference type="EnsemblBacteria" id="AQP44790">
        <property type="protein sequence ID" value="AQP44790"/>
        <property type="gene ID" value="RPIT_08250"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19511">
        <property type="protein sequence ID" value="SDZ19511"/>
        <property type="gene ID" value="SAMN05428934_11525"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08250"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ19511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="195" mass="21018" checksum="421E6F68661DFB2C" modified="2017-04-12" version="1">MRDFHKPVHRPADVLESLRGAGDPAELSSLANDTAAALLGRVRESEDPDMVDRVIAYADRNGVDDVAELWASAPAASLPGAMWRLYLLRHAVVTNPEATGYRFRRGLEVDGGVHQAIAGSRSAPTPDQVADLATTILRGAFTGDFADALERASAFARVLAFGSSDIDDHRQANGYDGIADELRGSARLWREGQLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFE9</accession>
    <name>A0A1Q2CFE9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Signal recognition particle receptor FtsY</fullName>
            <shortName evidence="5">SRP receptor</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsY</name>
        <name evidence="9" type="ORF">RPIT_08665</name>
        <name evidence="10" type="ORF">SAMN05428934_10743</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP-binding SRP family. FtsY subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08665"/>
    <dbReference type="EnsemblBacteria" id="AQP44852">
        <property type="protein sequence ID" value="AQP44852"/>
        <property type="gene ID" value="RPIT_08665"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97118">
        <property type="protein sequence ID" value="SDY97118"/>
        <property type="gene ID" value="SAMN05428934_10743"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08665"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031226">
        <property type="term" value="C:intrinsic component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00920">
        <property type="entry name" value="FtsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004390">
        <property type="entry name" value="SR_rcpt_FtsY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF7">
        <property type="entry name" value="PTHR43134:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="SSF47364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00064">
        <property type="entry name" value="ftsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="SRP54" evidence="8">
        <location>
            <begin position="349"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="34"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="184"/>
            <end position="191"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="266"/>
            <end position="270"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="328"/>
            <end position="331"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY97118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="377" mass="39882" checksum="5B9E20FFBFFD2DAE" modified="2017-04-12" version="1">MDWLFWVIIAVIGAAIVIAGVVVYADGRRQRLEGAEKQELEQPPTEEPPAERAEEPVADRAPGPRLDEPEAPSNRLARLRRRLSGSNNALARALADLLSVDRIDADTWDDFETTLITSDLGVGPTTELTDALRRRLAVDGVADPAQARQVLHEELLKLVDPTLDRSLNLTPTRDGDPAVVLVVGVNGTGKTTTVGKLARVLVAEGRSVVLGAADTFRAAAAEQLTTWGERVGVETVRGEEGADPASVAFEAVAKGAAEGTDVVIVDTAGRLHTKTGLMDELGKVKRVIEKKAPVSEVLLVLDATTGQNGMTQARIFAEVVDVTGIVLTKLDGSAKGGIVIQVQRELGVPVKLVGLGEGVDDLAPFEAEGFVQGILGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFK9</accession>
    <name>A0A1Q2CFK9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Regulatory protein, luxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_08655</name>
        <name evidence="4" type="ORF">SAMN05428934_10741</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44850">
        <property type="protein sequence ID" value="AQP44850"/>
        <property type="gene ID" value="RPIT_08655"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97073">
        <property type="protein sequence ID" value="SDY97073"/>
        <property type="gene ID" value="SAMN05428934_10741"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08655"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="457"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY97073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="526" mass="56484" checksum="C50F45F0BA7F251C" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFM8</accession>
    <name>A0A1Q2CFM8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2'-5' RNA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_09040</name>
        <name evidence="2" type="ORF">SAMN05428934_107121</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY98669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44919">
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        <property type="gene ID" value="RPIT_09040"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98669">
        <property type="protein sequence ID" value="SDY98669"/>
        <property type="gene ID" value="SAMN05428934_107121"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09040"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY98669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="198" mass="21708" checksum="D2683EE77FB0D43D" modified="2017-04-12" version="1">MRNFFDSMTPWERNDGSLHLYVVPDAALGDRLVEAQSHLQGIPDLPTMPRPWLHFTVNRLAQFDDIGQRELSRLAAALTERLVRVPAFDVELGAPQVQETAVEVVAPPTPGWDLLVNAVRDAALDTFGGTMPDSPHAPHVSLAYATGPVDSEWVAERLAGVGPLGTFRVGTVHLMSVTVRPEMGIFDFVELANWPLAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFP6</accession>
    <name>A0A1Q2CFP6_9ACTN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_09200</name>
        <name evidence="2" type="ORF">SAMN05428934_107152</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
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        <lineage>
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            <taxon>Propionibacteriales</taxon>
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    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP44939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09200"/>
    <dbReference type="EnsemblBacteria" id="AQP44939">
        <property type="protein sequence ID" value="AQP44939"/>
        <property type="gene ID" value="RPIT_09200"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY99305">
        <property type="protein sequence ID" value="SDY99305"/>
        <property type="gene ID" value="SAMN05428934_107152"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY99305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="168" mass="18744" checksum="73B32ADBC77781D9" modified="2017-04-12" version="1">MQRIELDHDKYSAYLNQHLVAADAGVKAFKAAADTWEGTPLQAVFEQLHRELEQSHDKVKALIERLGYDVSMTRNLVAGVAHVAGRLNPLNFTRNSDGLMTQMEFDALAAAVRAQQMMWETLVVLSDVDDRLDRAEMQAMVDLCEDQRARVVKASAETAVERFTAVPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFS8</accession>
    <name>A0A1Q2CFS8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09335</name>
        <name evidence="3" type="ORF">SAMN05428934_102442</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
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    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY60888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44963">
        <property type="protein sequence ID" value="AQP44963"/>
        <property type="gene ID" value="RPIT_09335"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY60888">
        <property type="protein sequence ID" value="SDY60888"/>
        <property type="gene ID" value="SAMN05428934_102442"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09335"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY60888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="123" mass="13825" checksum="D78D676144A93CB0" modified="2017-04-12" version="1">MNRQQPIQDHNKHCDSANRFPLPATPLSGARPPPRGKPVEPGGSDNYEQPLHPSQAEALLLARISPERFVRQMRVKADQKGWERIDWTVLVSKQRFVKTLAVRQGEAEALLPQVEAWLESGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFT6</accession>
    <name>A0A1Q2CFT6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09405</name>
        <name evidence="3" type="ORF">SAMN05428934_102426</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
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    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44974">
        <property type="protein sequence ID" value="AQP44974"/>
        <property type="gene ID" value="RPIT_09405"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY60444"/>
        <property type="gene ID" value="SAMN05428934_102426"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF12277">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
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    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY60444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="109" mass="11684" checksum="98F71CDE417DC12C" modified="2017-04-12" version="1">MATRSVDEIRVDLAANRAKLAEATAEAVEAVKPANIARESVDQVKQFAKGEFNAATSQLKDEQGGWRRDRLIAIGGAVLGTVLFFATLSAIAKRRTALELSMQHAVTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFW5</accession>
    <name>A0A1Q2CFW5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09580</name>
        <name evidence="3" type="ORF">SAMN05428934_102390</name>
    </gene>
    <organism evidence="2 4">
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY59503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09580"/>
    <dbReference type="EnsemblBacteria" id="AQP45006">
        <property type="protein sequence ID" value="AQP45006"/>
        <property type="gene ID" value="RPIT_09580"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59503">
        <property type="protein sequence ID" value="SDY59503"/>
        <property type="gene ID" value="SAMN05428934_102390"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09580"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021888">
        <property type="entry name" value="DUF3499"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12005">
        <property type="entry name" value="DUF3499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY59503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="130" mass="13997" checksum="BB65944500A0DE09" modified="2017-04-12" version="1">MRPQYARFGYLRWVRSCTRTACGAPAIATLTYVYADSTAVLGPLAQSPEPGTYDLCARHAERTSAPQGWDVIRLPLDGHEPEPTAPSDDLMALAEAVRAIGLRHDEPAPEPVPAPPVEGRGGHLRLVSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG28</accession>
    <name>A0A1Q2CG28_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transcriptional regulator WhiB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">whiB</name>
        <name evidence="13" type="ORF">RPIT_09600</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">The Fe-S cluster can be nitrosylated by nitric oxide (NO).</text>
    </comment>
    <comment type="PTM">
        <text evidence="11">Upon Fe-S cluster removal intramolecular disulfide bonds are formed.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the WhiB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09600"/>
    <dbReference type="EnsemblBacteria" id="AQP45010">
        <property type="protein sequence ID" value="AQP45010"/>
        <property type="gene ID" value="RPIT_09600"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09600"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035731">
        <property type="term" value="F:dinitrosyl-iron complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01479">
        <property type="entry name" value="WhiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034768">
        <property type="entry name" value="4FE4S_WBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003482">
        <property type="entry name" value="Whib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38839">
        <property type="entry name" value="PTHR38839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02467">
        <property type="entry name" value="Whib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51674">
        <property type="entry name" value="4FE4S_WBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 11" id="KW-0408">Iron</keyword>
    <keyword evidence="6 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 11" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="4Fe-4S Wbl-type" evidence="12">
        <location>
            <begin position="32"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP45010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="95" mass="10762" checksum="7024F0E8917B7195" modified="2017-04-12" version="1">MCNSVQRRGGRMDEMFDLLDDDGAFAWQAEALCAQTDPEAFFPEKGGSTREAKRVCLSCTVRTECLEYALAHDERFGIWGGLSERERRKLKRAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG58</accession>
    <name>A0A1Q2CG58_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Holo-[acyl-carrier-protein] synthase</fullName>
            <shortName evidence="8">Holo-ACP synthase</shortName>
            <ecNumber evidence="8">2.7.8.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">4'-phosphopantetheinyl transferase AcpS</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">acpS</name>
        <name evidence="10" type="ORF">RPIT_10080</name>
        <name evidence="11" type="ORF">SAMN05428934_102289</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>apo-[ACP] + CoA = adenosine 3',5'-bisphosphate + H(+) + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9690"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="EC" id="2.7.8.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the P-Pant transferase superfamily. AcpS family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.7" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10080"/>
    <dbReference type="EnsemblBacteria" id="AQP45094">
        <property type="protein sequence ID" value="AQP45094"/>
        <property type="gene ID" value="RPIT_10080"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56658">
        <property type="protein sequence ID" value="SDY56658"/>
        <property type="gene ID" value="SAMN05428934_102289"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10080"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00101">
        <property type="entry name" value="AcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002582">
        <property type="entry name" value="ACPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00516">
        <property type="entry name" value="acpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACPS" evidence="9">
        <location>
            <begin position="4"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP45094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY56658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="116" mass="12562" checksum="3EC069C13B7FD394" modified="2017-04-12" version="1">MIVGIGTDLCVIERFKTMLERRPGLAERLLTEGERALSIESQAARFAAKEALAKALGSPGGMRWLDCEVIKTDDGEPRFVTSGSVAARIEELGIETIHLSISHDGGFATTMVVCER</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG59</accession>
    <name>A0A1Q2CG59_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Bifunctional NAD(P)H-hydrate repair enzyme</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Nicotinamide nucleotide repair protein</fullName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="11">ADP-dependent (S)-NAD(P)H-hydrate dehydratase</fullName>
                <ecNumber evidence="11">4.2.1.136</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="11">ADP-dependent NAD(P)HX dehydratase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="11">NAD(P)H-hydrate epimerase</fullName>
                <ecNumber evidence="11">5.1.99.6</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="9" type="primary">nnrD</name>
        <name evidence="10" type="synonym">nnrE</name>
        <name evidence="13" type="ORF">RPIT_10075</name>
        <name evidence="14" type="ORF">SAMN05428934_102290</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 11">Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>(6R)-NADHX = (6S)-NADHX</text>
            <dbReference type="Rhea" id="RHEA:32215"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:64075"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 10 11">
            <text>(6R)-NADPHX = (6S)-NADPHX</text>
            <dbReference type="Rhea" id="RHEA:32227"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:64077"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 9 11">
            <text>(6S)-NADHX + ADP = AMP + H(+) + NADH + phosphate</text>
            <dbReference type="Rhea" id="RHEA:32223"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.136"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 9 11">
            <text>(6S)-NADPHX + ADP = AMP + H(+) + NADPH + phosphate</text>
            <dbReference type="Rhea" id="RHEA:32235"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.136"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 11">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="10 11">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the NnrE/AIBP family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 11">In the C-terminal section; belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 11">In the N-terminal section; belongs to the NnrE/AIBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.136" evidence="11"/>
    <dbReference type="EC" id="5.1.99.6" evidence="11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10075"/>
    <dbReference type="EnsemblBacteria" id="AQP45093">
        <property type="protein sequence ID" value="AQP45093"/>
        <property type="gene ID" value="RPIT_10075"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56688">
        <property type="protein sequence ID" value="SDY56688"/>
        <property type="gene ID" value="SAMN05428934_102290"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10075"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052855">
        <property type="term" value="F:ADP-dependent NAD(P)H-hydrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052856">
        <property type="term" value="F:NADHX epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052857">
        <property type="term" value="F:NADPHX epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046496">
        <property type="term" value="P:nicotinamide nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01171">
        <property type="entry name" value="YXKO-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01965">
        <property type="entry name" value="NADHX_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01966">
        <property type="entry name" value="NADHX_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000631">
        <property type="entry name" value="CARKD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030677">
        <property type="entry name" value="Nnr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004443">
        <property type="entry name" value="YjeF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01256">
        <property type="entry name" value="Carb_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03853">
        <property type="entry name" value="YjeF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017184">
        <property type="entry name" value="Nnr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="SSF64153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00197">
        <property type="entry name" value="yjeF_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51383">
        <property type="entry name" value="YJEF_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51385">
        <property type="entry name" value="YJEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="14" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="10 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0520">NAD</keyword>
    <keyword evidence="9 11" id="KW-0521">NADP</keyword>
    <keyword evidence="9 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="YjeF N-terminal" evidence="12">
        <location>
            <begin position="10"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="NADPHX" evidence="10">
        <location>
            <begin position="55"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="NADPHX" evidence="10">
        <location>
            <begin position="119"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="404"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR017184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP45093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY56688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="465" mass="47124" checksum="E292F06D48AA9835" modified="2017-04-12" version="1">MRTVVSSAEMRAAEQAVFARDPEADLMGKAAAAIARIADDVAPDGAVLVVAGAGNNGGDGLFAAALLAERRPVLFWRAFRDAHAAAVAAARAAGCREVDAVGAVAALADCSLVIDAVTGLGSRPGLPLALQTLVDACDAATVPVLSVDLPSGLDADSGALHPSFSAEHTVTFGSVKPCHVQQPAASRCGRVHIVDIGVTVPDTQLRVAEAADVARWWPRPDASSDKYSRGVVLVDTGSEQYQGAAVLSCSGALHAGAGMVRYTGRAASGLILSRFPSVVVGEGRAQAIVLGSGWGDSDGGEGRVALARMHSLPAVVDADALHWLPGGRLDGWLLTPHAGELARLLGCTRAHVEAHPLSCVREAARHTGATVLLKGATQYVAEPSGRVTIAVAGPPWTAQAGSGDVLAGICGALLAAGLPAWRAGVLGASIQAMTAAANPGPYTPDELAARLPAMIAQLSSSPLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG71</accession>
    <name>A0A1Q2CG71_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Iron-sulfur cluster carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_10135</name>
        <name evidence="8" type="ORF">SAMN05428934_102278</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the MIP18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10135"/>
    <dbReference type="EnsemblBacteria" id="AQP45104">
        <property type="protein sequence ID" value="AQP45104"/>
        <property type="gene ID" value="RPIT_10135"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56362">
        <property type="protein sequence ID" value="SDY56362"/>
        <property type="gene ID" value="SAMN05428934_102278"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10135"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="PTHR42961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="6">
        <location>
            <begin position="10"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="122"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY56362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="383" mass="40780" checksum="808C02EC55BFD702" modified="2017-04-12" version="1">MTEHPLLPHVRAALHQVEDPEIRRPITELGMVDEIRADDDGNVFVRVLLTVAGCPMRSEITGRVTSAVTAVDGVSSVDVELGVMNDEQREAMRTMLRGGQQQRAIPFAQPGNLTRVLAVASGKGGVGKSSVTVNLALALAKQGRAVGILDADIYGHSIPDLLGLGDARPTVVDDMIMPVPAMGGLRVISIGMLKPSRDQVVAWRGPILDRALTQLLADVYWGDLDYLLLDLPPGTGDVAMSLGQKIPSSEVLVVTTPQTAASEVAERAGTMAHILEQRVLGVVENMSWMETTCPHCEQSHRLELFGSGGGALVAEALTERFVYEVPLLAQIPFDESLLSGGDRGTPIVESHPDHPSAQAITGLAEQVASRKKGLLGTRLPLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG72</accession>
    <name>A0A1Q2CG72_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized membrane protein, DUF485 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09810</name>
        <name evidence="3" type="ORF">SAMN05428934_102344</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY58196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09810"/>
    <dbReference type="EnsemblBacteria" id="AQP45045">
        <property type="protein sequence ID" value="AQP45045"/>
        <property type="gene ID" value="RPIT_09810"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY58196">
        <property type="protein sequence ID" value="SDY58196"/>
        <property type="gene ID" value="SAMN05428934_102344"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09810"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007436">
        <property type="entry name" value="DUF485"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04341">
        <property type="entry name" value="DUF485"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY58196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="114" mass="12911" checksum="08B7C025CA4394A6" modified="2017-04-12" version="1">MTDPSPDLGTIPAEEFHRVQQSAEFADLKKTFRSFAFPMTVVFLLWYFAYVLGSIFAKDLMMTSVVGNLTVGILFGLGQFVSTFLITWLYIRHSNKRVDPLAKALREDLEASAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG83</accession>
    <name>A0A1Q2CG83_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10285</name>
        <name evidence="3" type="ORF">SAMN05428934_102248</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10285"/>
    <dbReference type="EnsemblBacteria" id="AQP45132">
        <property type="protein sequence ID" value="AQP45132"/>
        <property type="gene ID" value="RPIT_10285"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55529">
        <property type="protein sequence ID" value="SDY55529"/>
        <property type="gene ID" value="SAMN05428934_102248"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10285"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="1">
        <location>
            <begin position="14"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY55529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="171" mass="18459" checksum="F5E2564EDC9223BE" modified="2017-04-12" version="1">MAYHADSTDHADKEVLTWEGFGRAQRELAQAVLDSGFEPTIIIAVARGGMSLAGALTYALGVKLTDAINVEFYTDVHETLPDPVLLAPMLDTESIAGQRILVADDVADSGRTLGLVMKLLRGFGADVRSAVLYSKPSTIVAPDYVWKATDQWIVFPWSDEPPVQRRGGQGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG99</accession>
    <name>A0A1Q2CG99_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucose-6-phosphate 1-epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10295</name>
        <name evidence="2" type="ORF">SAMN05428934_102246</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10295"/>
    <dbReference type="EnsemblBacteria" id="AQP45134">
        <property type="protein sequence ID" value="AQP45134"/>
        <property type="gene ID" value="RPIT_10295"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55471">
        <property type="protein sequence ID" value="SDY55471"/>
        <property type="gene ID" value="SAMN05428934_102246"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10295"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY55471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="263" mass="27902" checksum="65605DF10EB12577" modified="2017-04-12" version="1">MHTVKGDWGRGAVSELGACVVSWSPAGFGEQLFLARDAALVPGEMWHGGVPICAPWFGSGTGEWTVPHIHGLVSRVPWRVLSLREDDDCARIELAVSAAETAHLAGADRYPDDLAYSLSVEMGRRLRLALTIASPSRQVTVDQAFHPYLAVQANQAQLTGLEGLRFRDYAADGGPTSQSSPVRFGRYVDRVYDGAPTTLLSDGSRSLAMSGTGAGSVVVWNPGPGGDEWASFACVEYGNVQNRAVVIPAGGTHTLALTITPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGI4</accession>
    <name>A0A1Q2CGI4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10490</name>
        <name evidence="3" type="ORF">SAMN05428934_102207</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY54356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45170">
        <property type="protein sequence ID" value="AQP45170"/>
        <property type="gene ID" value="RPIT_10490"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY54356">
        <property type="protein sequence ID" value="SDY54356"/>
        <property type="gene ID" value="SAMN05428934_102207"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10490"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544482" evidence="1">
        <location>
            <begin position="28"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY54356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="290" mass="31842" checksum="C8E7024E7DEA88D5" modified="2017-04-12" version="1">MKLRSLIVSLASGALIATGLIVPPAHAVDPVVRVSCPAVAAVNKALGTTTLTHLTSRLDACSYASQPIAHSTDAQLIMVLDRGTPADTQRAIEDGWPNDYPYSFSPVPVPELGAGAFWWADASPMMAHWQVSPGLVGLLTGGLLTPQNLAATARLFRPMMEVYTVPGEHTVNGRRWRTTCEDYSQTERCRTEIWATVITVVGGRYLRTDGWAFNSLTYRWSDRTLWKTNPLGDTGSWTSTDGRQWKTECDNAASGRGACRSYRMTTVVGWTGSAYKQENKWVLNNQVLFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGI7</accession>
    <name>A0A1Q2CGI7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-2 type transport system ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Multidrug ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_10765</name>
        <name evidence="6" type="ORF">SAMN05428934_102152</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY52643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10765"/>
    <dbReference type="EnsemblBacteria" id="AQP45217">
        <property type="protein sequence ID" value="AQP45217"/>
        <property type="gene ID" value="RPIT_10765"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY52643">
        <property type="protein sequence ID" value="SDY52643"/>
        <property type="gene ID" value="SAMN05428934_102152"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10765"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY52643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="313" mass="32631" checksum="578743A4465DC1A5" modified="2017-04-12" version="1">MSAPAIETSGLTKRFRSGQVAVDGVDLAVPHGAVYGFLGPNGSGKTTTIRMLLGLVSPTAGSARLLGQPMPGDALEVLPRVGALVEGPAFHPYLSGRANLARLDACDSTASRSSSPRRIGEALERVGLTAAARKPYRQYSLGMKQRLGLAAALLRPRDLLVLDEPTNGLDPQGTREVRHLIRELAAEGATVLVSSHLLAEIEQVCTHIGIMSQGRLLAQSERAALVADDAATLVVTTGLDHVTTAAEVLRGLGLEPITAEGTHLSASLGATAPSQVAAALVHAGVAVDGLEVRRRSLEQLFVELTGEGFDVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGM8</accession>
    <name>A0A1Q2CGM8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nitrate reductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Uracil-xanthine permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_11000</name>
        <name evidence="7" type="ORF">SAMN05428934_102103</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY51110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11000"/>
    <dbReference type="EnsemblBacteria" id="AQP45257">
        <property type="protein sequence ID" value="AQP45257"/>
        <property type="gene ID" value="RPIT_11000"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY51110">
        <property type="protein sequence ID" value="SDY51110"/>
        <property type="gene ID" value="SAMN05428934_102103"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11000"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="256"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="421"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY51110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="472" mass="49160" checksum="B1DC001C3C4C411D" modified="2017-04-12" version="1">MWKLHNNGVLLPDAVVTPTERLTWGRTVGLGAQHVVAMFGATFVFPLLMGLNPQLAVMMSGVATLLFLFVVKHRVPSYLGSSASFVGVATAVYTAGGNPATLTGALFVVGLLLFMAGLIIHFAGARVIHRALPPVVTGAVVMLIGFNLAPVVASEYWPVDPWLAFLVMLIVVGLSIGLRGFWGRIAIFLSLVVGYVLSWAADVVMGPLQTADGARPRVDWSNVAAADWIGFPPLTDLANWTYGATDNVVGFHLPQFSLGAIIVAMPVVIALIAENTGHVKAVAEMTKDDLDPLMGRAIAADGAGSMVATLVGAGPTTTYAENIGVMAASRVYSTAAYVVAAVVAILFGFSPKFGAVISATPSAVLGGITVVLYGMIGLLGAKIWKENNVDFGNPLNLIPASAGIIIGIGNVSVPLGGDFELGGIALGTIVTIGVYHLARIIAPRTMREQADGASIIYDAPGIYTDEDATPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGR8</accession>
    <name>A0A1Q2CGR8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_11230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11230"/>
    <dbReference type="EnsemblBacteria" id="AQP45297">
        <property type="protein sequence ID" value="AQP45297"/>
        <property type="gene ID" value="RPIT_11230"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11230"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="231"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="269" mass="29766" checksum="B8DBB5C173C73D5C" modified="2017-04-12" version="1">MTDERPDDDPQPPAPEPESAPSEPGQSISDGEPAEKEWWDDDGMPWKKKPGREDYACLAWFGVVGVFSLLLLPTRAWLIATAPDWLAMITGGRTAVAVSGALASQGEMPHWPIVLAVASVLSLKFDWIYWWAGKLWGRGMIEVWAGQSKRAARGYARAERWAEKLGPLGFLIAYVPLPLPLMQVVFVLAGATGMGIKRFLVYDYIASTLWLVLYFYLGWRFGEPIVDVLEAYARIAMWVALGLIAFIFVSTYLAQRRKAREGASGGDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGR9</accession>
    <name>A0A1Q2CGR9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_11315</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11315"/>
    <dbReference type="EnsemblBacteria" id="AQP45311">
        <property type="protein sequence ID" value="AQP45311"/>
        <property type="gene ID" value="RPIT_11315"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11315"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="160"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="391" mass="42430" checksum="6DBB268910B21F75" modified="2017-04-12" version="1">MMIDMHPALAGLIGAGLALTCCLFVYLVYRGREGWRQLEAQRQAEKASAELRDVLSTVASGALLVGPHDEILMVNEAGEALGLARGNRVGFPELLDRVRAVRSSGEQYRGPIVRAAHPGVEGLELAARVSPMVDDNVLVIADDESAQRRVDAVRRDFVANISHELKTPIGAVSVLAEAIEAASDDPESVQRFATRMQVEAARLAELVNQIIDLSRLQSSDPMLTRELVAVDEIVSEAIARSQERANKRHVNLILASTARVSVMGDRWQLVDAVSNLVQNAINYSDERARVAVSVIPTTVDGVPVVEIKVSDNGIGIRPEDQERIFERFYRVDYGRSRQSGGTGLGLSIVRHIAVAHGGSVRVWSRPGQGSTFTLQLPAHPGDQPDTEESSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGT9</accession>
    <name>A0A1Q2CGT9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alcohol dehydrogenase, class IV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_11350</name>
        <name evidence="4" type="ORF">SAMN05428934_10233</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY49009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11350"/>
    <dbReference type="EnsemblBacteria" id="AQP45317">
        <property type="protein sequence ID" value="AQP45317"/>
        <property type="gene ID" value="RPIT_11350"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY49009">
        <property type="protein sequence ID" value="SDY49009"/>
        <property type="gene ID" value="SAMN05428934_10233"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11350"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="2">
        <location>
            <begin position="10"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY49009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="379" mass="38623" checksum="AAAF930D8D829E4D" modified="2017-04-12" version="1">MTDFTFATAAKIRFGAGAAAELPAFSAELGERVFLVTGANPQRTENLAGKLSVVGTFGVADEPTFNDARAAVAEARAAKADQVVGIGGGAVLDLAKAVAALAVDGGDPMDHAEVIGAGRSMPARGLPFIAVPTTAGTGSEVTANAVLTSQEHRVKVSLRSPAMLAKVAVVDPELTVTCPADVTMYSGIDALTQCLEPLTSRFTNPMVEALALAGLRAAGRSLLRAVDQGEDLEARSDMAFCSLMGGLSLANAKLGAVHGLAGVLGGVTGAPHGAICAALLEPVTAGNIAALLERAPKHLALAGYLNAAEALTGHRQIEALGTWLGELEHQLDLPGLDDLGLDRFDHGAVVDQAMKASSMKGNPIDLTRDELLAILDAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGZ0</accession>
    <name>A0A1Q2CGZ0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methylmalonyl-CoA carboxyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Methylmalonyl-CoA carboxyltransferase 12S subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_11365</name>
        <name evidence="4" type="ORF">SAMN05428934_10230</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY48904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11365"/>
    <dbReference type="EnsemblBacteria" id="AQP45320">
        <property type="protein sequence ID" value="AQP45320"/>
        <property type="gene ID" value="RPIT_11365"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY48904">
        <property type="protein sequence ID" value="SDY48904"/>
        <property type="gene ID" value="SAMN05428934_10230"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11365"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
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    </dbReference>
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        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000438">
        <property type="entry name" value="Acetyl_CoA_COase_Trfase_b_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
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        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ACCCTRFRASEB"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="COA_CT_CTER"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="7"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="2">
        <location>
            <begin position="269"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY48904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="518" mass="55439" checksum="1EC09D8C0FD64DAE" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH44</accession>
    <name>A0A1Q2CH44_9ACTN</name>
    <protein>
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        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">RPIT_11970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11970"/>
    <dbReference type="EnsemblBacteria" id="AQP45427">
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        <property type="gene ID" value="RPIT_11970"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11970"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012551">
        <property type="entry name" value="DUF1707"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08044">
        <property type="entry name" value="DUF1707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="204" mass="21790" checksum="BCB9F2B79F661595" modified="2017-04-12" version="1">MSRDLPERRMRAGDADRDQVLTVVQRAYEAGRLDLEEMRDRQEKALKARFTDELPALVADLPEGVALAVPDGAPVVPRPDDLPDTGLTDAGFGVSIMSGRDVTLQRGTREFSNLAFWGGNNIDLTSAMGPGRIVTLTLHAIMGGNDVVVPEGVRVIDQSVAIMAGNGIAAEAQGDGSNGTLVLKGFLWWGGNDVKLRAARDPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH67</accession>
    <name>A0A1Q2CH67_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12090</name>
        <name evidence="3" type="ORF">SAMN05428934_10658</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY91925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45451">
        <property type="protein sequence ID" value="AQP45451"/>
        <property type="gene ID" value="RPIT_12090"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY91925">
        <property type="protein sequence ID" value="SDY91925"/>
        <property type="gene ID" value="SAMN05428934_10658"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12090"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY91925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="117" mass="12602" checksum="21E961B711A21166" modified="2017-04-12" version="1">MSHDPFGTDDGATADAVSFDVGRTPLVWIVSALVTAVLGGVLAFMAQGWVLLGAWFLAGPASFGLIAFFVNRDTRQRLKPVYGQSTLFPALYWIAIGMTMVAVVWCAYQLALFVGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHF3</accession>
    <name>A0A1Q2CHF3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FHA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_12690</name>
        <name evidence="4" type="ORF">SAMN05428934_104149</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY79125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12690"/>
    <dbReference type="EnsemblBacteria" id="AQP45556">
        <property type="protein sequence ID" value="AQP45556"/>
        <property type="gene ID" value="RPIT_12690"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY79125">
        <property type="protein sequence ID" value="SDY79125"/>
        <property type="gene ID" value="SAMN05428934_104149"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12690"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
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        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="80"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY79125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="153" mass="16432" checksum="3C5DD18006215D3F" modified="2017-04-12" version="1">MSDLIIAAIKVAFLALLWLFILAIANTVRTDMFGKRVPASSLTAIPADRGRGKGRSKSPTRFAITAGPQQGTAVPVAPTINLGRAADSTLLLDDDYASARHAQLVQQDSNTWLISDLRSTNGTYVNGRLVTEPTKVTVGDVVRIGKTLMRLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHL5</accession>
    <name>A0A1Q2CHL5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Alanine dehydrogenase</fullName>
            <ecNumber evidence="2 5">1.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_13030</name>
        <name evidence="13" type="ORF">SAMN05428934_10481</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the reversible reductive amination of pyruvate to L-alanine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + L-alanine + NAD(+) = H(+) + NADH + NH4(+) + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:18405"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="1.4.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid degradation; L-alanine degradation via dehydrogenase pathway; NH(3) and pyruvate from L-alanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the AlaDH/PNT family.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.1" evidence="2 5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <sequence length="374" mass="39244" checksum="0250304C94C406F9" modified="2017-04-12" version="1">MRIGVPREVKNSEHRVGMTPVGVHELVQRGHELIVEHDAGLGSSFTDDDYRKAGATVVDDAPEVWGSAELVLKVKEPTPDEFGLLREDLTLFTYLHLAADEPLVDALLDAGTTAIAYETVQLDSGQLPLLHPMSEVAGCLATQAGASHLLKHRGGRGILLGGIGGVANSEVLVLGAGVAGQSATNIAVGLGANVTLLDTDLGKLRAALARWGNRVTTLASSEIAIRDQLAGADLVIGTVLIPGARAPKLVSDEMIAGMKSGSVLVDVAIDQGGCFEPSRPTTHEDPTFRVHDSLLYCVTNMPAAVPHTSTWALTNATLPYVNALAEHGWRGAMEADATLRRGLSTHAGTLTSVPVAESFDRESVPAEDVLGIEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
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        <lineage>
            <taxon>Bacteria</taxon>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="1"/>
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        </location>
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            <end position="181"/>
        </location>
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        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45618.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="181" mass="18036" checksum="FED73EA43B3D9E62" modified="2017-04-12" version="1">MVLSGVTLAVVPAAPAVACSCAVSSTAEYAERADLVAVGTITGREVPENATSSADDATWTVEIDKVYKGDATPTVPVLTALEGPSCGWDHVSSGQTIILFANLDGEDVRSDLCSGTGAFTPELDAELATLLGSPAAPTEAPAAAPDEGGLETRTVVGLALLIAAAVVLVAGAARRHHGVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHQ0</accession>
    <name>A0A1Q2CHQ0_9ACTN</name>
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        <submittedName>
            <fullName evidence="8">Aquaporin family protein</fullName>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="8" type="ORF">RPIT_13150</name>
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    </gene>
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            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
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        <property type="protein sequence ID" value="AQP45637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY76587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13150"/>
    <dbReference type="EnsemblBacteria" id="AQP45637">
        <property type="protein sequence ID" value="AQP45637"/>
        <property type="gene ID" value="RPIT_13150"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY76587">
        <property type="protein sequence ID" value="SDY76587"/>
        <property type="gene ID" value="SAMN05428934_10457"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13150"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015267">
        <property type="term" value="F:channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="SSF81338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY76587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="257" mass="25917" checksum="39CF346600AC1543" modified="2017-04-12" version="1">MEEVSLGVVFLSEVVGSAMLLLLGGGVVANAILAKTKGLGGGWLLINFGWGLAVFAGVLVSYKSGGHINPAVTFGILASGADSYAAGVAITAASTVVYVVAQLLGAMIGALLTWVAYKQHFDAEPDPGKKLGVFSTGAEIRNPMWNVITEIIGTFVLVFVVLAAGNWGDADTATPAGLGWLGALGVALLVVGIGASLGGPTGYAINPTRDLGPRIMHAILPIKGKGSSDWGYSWIPIVGPLIGGVLAGLLSGALLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHS1</accession>
    <name>A0A1Q2CHS1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13255</name>
        <name evidence="3" type="ORF">SAMN05428934_10436</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY75986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45657">
        <property type="protein sequence ID" value="AQP45657"/>
        <property type="gene ID" value="RPIT_13255"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY75986">
        <property type="protein sequence ID" value="SDY75986"/>
        <property type="gene ID" value="SAMN05428934_10436"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13255"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021354">
        <property type="entry name" value="DUF2975"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11188">
        <property type="entry name" value="DUF2975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY75986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="159" mass="17066" checksum="79D393A17B6F685C" modified="2017-04-12" version="1">MRKWLVWAVRALIVVMTLGALAIMGGLLPMFGLSAVEEFPEVSYLFWPTLVLTETFMVAALVVLGSMWVLVGMVGRDQVFTARAWRYVDAIIVAFLVAAAISGFTLVWIVGFVDVGGPPIGMLGMVASVGSLAGATLMALMRGLLVKATEMRDELAEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHW1</accession>
    <name>A0A1Q2CHW1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Monosaccharide ABC transporter substrate-binding protein, CUT2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13270</name>
        <name evidence="4" type="ORF">SAMN05428934_10433</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY75903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13270"/>
    <dbReference type="EnsemblBacteria" id="AQP45660">
        <property type="protein sequence ID" value="AQP45660"/>
        <property type="gene ID" value="RPIT_13270"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY75903">
        <property type="protein sequence ID" value="SDY75903"/>
        <property type="gene ID" value="SAMN05428934_10433"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13270"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544518" evidence="1">
        <location>
            <begin position="28"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="2">
        <location>
            <begin position="43"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY75903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="314" mass="31925" checksum="B4B687EA52B594C2" modified="2017-04-12" version="1">MKLRRSLSALGVAVVGALTLTACGGEATTPDPAETTAGGDVTVTVVTPYLANAATKEVIDLFTAEGEERGWEVSVVDTAGDMNKLNSAFQDAAAQQPDAIVLGTGDPTQISLGLKAAADAEVPVFAIDAGEAEGFAANVTSDNADLGDQSAKALIEAMGGEGQVVMMTHDPHPGVRARAEGARQAFEAAGITVLEEKHVNVPGPVDDARTSVQDILSARGGEVTGIWGGWDEPALGATQALEAAGVDGVPVVGVDGQDFALAAIEEGGPFVATVKQDWPAIAAKVAELVEDQVTNGTAPDQKNYELPGTLITAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHZ8</accession>
    <name>A0A1Q2CHZ8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">DNA replication and repair protein RecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">recF</name>
        <name evidence="10" type="ORF">RPIT_13645</name>
        <name evidence="11" type="ORF">SAMN05428934_11170</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7 8">The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the RecF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13645"/>
    <dbReference type="EnsemblBacteria" id="AQP45724">
        <property type="protein sequence ID" value="AQP45724"/>
        <property type="gene ID" value="RPIT_13645"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12878">
        <property type="protein sequence ID" value="SDZ12878"/>
        <property type="gene ID" value="SAMN05428934_11170"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13645"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00365">
        <property type="entry name" value="RecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001238">
        <property type="entry name" value="DNA-binding_RecF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018078">
        <property type="entry name" value="DNA-binding_RecF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042174">
        <property type="entry name" value="RecF_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32182:SF0">
        <property type="entry name" value="PTHR32182:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00611">
        <property type="entry name" value="recf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00617">
        <property type="entry name" value="RECF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00618">
        <property type="entry name" value="RECF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 8" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="SMC_N" evidence="9">
        <location>
            <begin position="3"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="30"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP45724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDZ12878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="381" mass="41318" checksum="871037A01A5F0A6C" modified="2017-04-12" version="1">MFVTELSLVDFRNYREASLDLTAGVTVFVGANGQGKTNLVEAVEYLSTMSSHRVSATAPLIRAGAETAVVRAKVQAGREDPRLITLELEIANGRSNVARLNRAPLSRPRDLIGALRTVVFSPMDLAIVRGDPSDRRAWLDSLVTTRWPRMVGVRQDLDRVLKQRNALLKAMAGRSFKPSGGDEETTLAVWNDQLAAIGAELLHARLDTLADVTPHAQRAYETIAPVNNQISTSYKTVLDLDGLAGAADVRGELQRRLLDAMERLRRDEIARGVTLVGPQRDDVELFIGPLPAKGYASHGESWSLALALRLGGYTLVRADGVEPVLVLDDVFAELDVSRRERLAAAIADAEQVLITAAVGADVPDFPAERRFTVDAGTVSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI15</accession>
    <name>A0A1Q2CI15_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Membrane protein involved in the export of O-antigen and teichoic acid</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_13825</name>
        <name evidence="7" type="ORF">SAMN05428934_11135</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13825"/>
    <dbReference type="EnsemblBacteria" id="AQP45751">
        <property type="protein sequence ID" value="AQP45751"/>
        <property type="gene ID" value="RPIT_13825"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12228">
        <property type="protein sequence ID" value="SDZ12228"/>
        <property type="gene ID" value="SAMN05428934_11135"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13825"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002797">
        <property type="entry name" value="Polysacc_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01943">
        <property type="entry name" value="Polysacc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="311"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="341"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="378"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="466"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ12228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="505" mass="55367" checksum="C79C8B898E8504A3" modified="2017-04-12" version="1">MSLTRFDFARRNAGFGLISTLVTVVLGFVSRSIFIAELGAAYLGVNTLMLNVVGVLSFAELGIGSAMSYSLYKPVAEGDAPLVRALSDFYKKAYRVIALIVTIVGLALLPFIPNLANEAGDLGDLRVYYTLYLLANVMSYFAVYKTGLATAEQRTYLVTNIRTVASVVLQVAQIVSLLIWGDFLIYLVVMVLARAAEQLFLNVYLSRRYRNYLQPPDAPLRQEQLEPIKRNVKALIWHKLGDVAVNQTDSIIIAAFVNVTVLGFIANYNLIINTASMLLLVIMNAAIGSFGNAIATAAPKDVYRNYKTYRFAAFWIYGMATAGMYALITPLITLWLGPDMVIPQEVALLILLNFYLLGQRATVNTVKSAAGIWDADKYLPLIQAIVNLGLSIILVQAVGLVGVFIGTLAQGLLATIVRPLIVYPRVFGSPAREYFIDGAKYLLVLVVAAVSSALAVDAWLGPITLGSMLLAILCVGLWINLIFALVFGRRPEFTELVRRLSPRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI56</accession>
    <name>A0A1Q2CI56_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Radical SAM/SPASM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_14180</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14180"/>
    <dbReference type="EnsemblBacteria" id="AQP45809">
        <property type="protein sequence ID" value="AQP45809"/>
        <property type="gene ID" value="RPIT_14180"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14180"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017200">
        <property type="entry name" value="PqqE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037420">
        <property type="entry name" value="PQQ_syn_pqqE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
        <location>
            <begin position="25"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="404" mass="44536" checksum="7336E05F26624925" modified="2017-04-12" version="1">MSPHPGSHPHEARKGVVRTLHHDAGERPHVLVWEVTRACQLACRHCRADAFTRADPRQLTTDEGKALLDSFASYGTPRPIVILSGGDAFERDDLEELIAYGTSIGLPIALSPSVTPLLTDERLASVREAGVKAFSLSLDGATPETHDSFRGIEGTFDDTMAAAKLVVKHGFRFQVNTTICRNNLRELPQLLATAMSMQAHMWYVLFLVPMGRGSNLEPLSPEEMEDVLHWLHDVSDRIAVKVTEAPNYRRVAIQRDDARTAGQPMPPTGELHAWLTEETERLLGEVTERRPPRPPIGVNSGRGFAFVDHIGDVYPSGFLPHRCGSVKEQSFPEIYAEAPMMKALRDPSSYEGKCGVCEFNWICGGSRARAHAMLGDPLASDPTCVWIPEAWRPSAPVIPELVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI74</accession>
    <name>A0A1Q2CI74_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat (LRR) protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_14270</name>
        <name evidence="4" type="ORF">SAMN05428934_11236</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ14880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45826">
        <property type="protein sequence ID" value="AQP45826"/>
        <property type="gene ID" value="RPIT_14270"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ14880">
        <property type="protein sequence ID" value="SDZ14880"/>
        <property type="gene ID" value="SAMN05428934_11236"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14270"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544524" evidence="2">
        <location>
            <begin position="23"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ14880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="582" mass="61970" checksum="38121EA04E3FA6CF" modified="2017-04-12" version="1"> </sequence>
</entry>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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                <person name="de Groot N.N."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <dbReference type="Proteomes" id="UP000188324"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
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            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="109" mass="11519" checksum="86A54412E87A6D41" modified="2017-04-12" version="1">MGRRRKLWWATWPGALGFGAASLLLVLPALFAAVVFVSLRGDDSAGLDFQVEGPGAVSRILAVLLFIGAATLPVLTARWARKRWAGYLLLGVGLSAVAFIVGLIMLGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 7">RP1T</strain>
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    <reference evidence="6 8" key="2">
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                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="5" key="3">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
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        </source>
    </reference>
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        </subcellularLocation>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
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        </location>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006223-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDZ05475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="104" mass="11623" checksum="507778A5408784CB" modified="2017-04-12" version="1">MPTNTLNGRSFQVNEEGFLTERSEWSEELAADLAALIDLELTDAHWAALRFMRDDSAPTGVTPTLRRMQTVGGFDIKELYRLFPVKPAKKMSWLAGLPKPVGCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIG9</accession>
    <name>A0A1Q2CIG9_9ACTN</name>
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        <recommendedName>
            <fullName evidence="7">Transporter</fullName>
        </recommendedName>
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        <name evidence="10" type="ORF">SAMN05428934_11257</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
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            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
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        <property type="protein sequence ID" value="AQP45845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ15260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14375"/>
    <dbReference type="EnsemblBacteria" id="AQP45845">
        <property type="protein sequence ID" value="AQP45845"/>
        <property type="gene ID" value="RPIT_14375"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ15260">
        <property type="protein sequence ID" value="SDZ15260"/>
        <property type="gene ID" value="SAMN05428934_11257"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14375"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="PTHR11616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SSF161070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00610">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0769">Symport</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="228"/>
            <end position="252"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="264"/>
            <end position="289"/>
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    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="323"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="360"/>
            <end position="387"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="435"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="473"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ15260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="519" mass="56379" checksum="BFF5838941BDC614" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CII7</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP45922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="SAMN05428934_10955"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ05637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="203" mass="21227" checksum="E0AA568ECB1D551C" modified="2017-04-12" version="1">MEDVVIKPSMGRTVIVLLVCVAFTIGGVLLILSGGLFDIALGIAAIVTFGGGGGYYLSKALRSSTTFTLTPRGIDVGAGGFVPWSHVGRIGQTKVAGGVQALGVEVRNVAAYVGTLTPEQQRAALRTAKFGQRVGRSAPATDGDKSGDLDSIRKRDLAAALNWTAARSDGYHLIFPLLTLNKPADKLAEEVKAYRAKATGRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIZ2</accession>
    <name>A0A1Q2CIZ2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADH_N" evidence="1">
        <location>
            <begin position="33"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="543" mass="57547" checksum="FB1926A468E21FAA" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIZ6</accession>
    <name>A0A1Q2CIZ6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_08385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP46087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP46087">
        <property type="protein sequence ID" value="AQP46087"/>
        <property type="gene ID" value="RPIT_08385"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08385"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP46087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="79" mass="9117" checksum="40A56D6F8E799C3E" modified="2017-04-12" version="1">MARLNREHSRMLGNGYCIRPQIMDCIYETICESCTFFQTTIEFRPTLLAQRDDACAKGQIRRAEIYDNLLTGLDTHEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ02</accession>
    <name>A0A1Q2CJ02_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_09115</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09115"/>
    <dbReference type="EnsemblBacteria" id="AQP46099">
        <property type="protein sequence ID" value="AQP46099"/>
        <property type="gene ID" value="RPIT_09115"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
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        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="130"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="136"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP46099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="374" mass="40391" checksum="D97A804CBB5FED49" modified="2017-04-12" version="1">MHDLDASGDSELKIGSLFTGYGGLDLAVEHVFNAKTAWFSELNEPVARVFSRHWPETSNLGDITTLDWSHVEPVDILIGGFPCQDVSTVGKRAGLAPGTRSGLWAHMAAAIDALQPEWVVIENVRGLLSSPATRPAAEGDDHDRRDPGDATPDGATLRGMEPDPWHLGDNATRPLRALGAVLGDLADLRLDARWIGLPASHVGAPHQRFRIFALARRTVPHSTSDGLIARRGDSRSGASETRDDRAVAPDHRLRAPRTGWLTEQEGRIGDAVVPDRWTVQRWGRYADAIARWEHITGRAAPAPALLNDADGPRPAPAFVEWLMGLPTGWVTDTDDLTFSQQITMLGNGVLPLQATSALATLTRCESVPGPSSPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ07</accession>
    <name>A0A1Q2CJ07_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_10700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10700"/>
    <dbReference type="EnsemblBacteria" id="AQP46128">
        <property type="protein sequence ID" value="AQP46128"/>
        <property type="gene ID" value="RPIT_10700"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10700"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007060">
        <property type="entry name" value="FtsL/DivIC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04977">
        <property type="entry name" value="DivIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012071822" evidence="3">
        <location>
            <begin position="24"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="112"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="26"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP46128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="140" mass="15478" checksum="9806B13E1E2E15BB" modified="2017-04-12" version="1">MLVVIAGITIVLANSLRVYFAQAQEIAAVKADIAATQEQIADLEDRLNRWEDPAYVRSVARVRLGWVMPGEVGYRVLGVDGQPLEGPSIETALDVEVPGLWWEKMWGSVRVADAPVEEEPADTMPDPERTIQPPNPDEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ51</accession>
    <name>A0A1Q2CJ51_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_11600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP46141">
        <property type="protein sequence ID" value="AQP46141"/>
        <property type="gene ID" value="RPIT_11600"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05830">
        <property type="entry name" value="Sortase_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005754">
        <property type="entry name" value="Sortase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023365">
        <property type="entry name" value="Sortase_dom-sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042003">
        <property type="entry name" value="Sortase_E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04203">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63817">
        <property type="entry name" value="SSF63817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01076">
        <property type="entry name" value="sortase_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="216" mass="22594" checksum="08D1F55C76EF158D" modified="2017-04-12" version="1">MSPLAVLGAVVLVVLLIAGGWAAWQFWGANLVAADDAAESVVSLRDGWSASPAVPDPDADPEAPPAVSQPAMGEPAWVLRIPRLNLEWPIVAGVDEADLRNGVGWYPSTALPGQAGNFALAGRRTTEGAPFRDLLTLGEGDEVIVETRAAVFTYTITAAPAALTVARSESWVLDPVPGHTDVVPTRALITLTTEEDLAPSDDISVGFGTLTMTETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ52</accession>
    <name>A0A1Q2CJ52_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0502 protein RPIT_12210</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_12210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0502 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12210"/>
    <dbReference type="EnsemblBacteria" id="AQP46149">
        <property type="protein sequence ID" value="AQP46149"/>
        <property type="gene ID" value="RPIT_12210"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12210"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01584">
        <property type="entry name" value="UPF0502"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007432">
        <property type="entry name" value="DUF480"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38768">
        <property type="entry name" value="PTHR38768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04337">
        <property type="entry name" value="DUF480"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="2">
        <location>
            <begin position="230"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="386" mass="42283" checksum="E6642EA7B819CFB5" modified="2017-04-12" version="1">MLSPEEQRVLGCLLEKQITVPDSYPLTMAALRTACNQKSSRDPVTDYDERTVQDTARMLKDRGLVRVTWLDYGRRTLKYAQTAVEALGLADDERALLTVLLLRGPQSPGELKTRADRMHEFDDRGEVEAVLQRMAAREEPLVARLERRPGQQDHRWAHTLGEAPVDAPAPAVDREQVLAEGSEARDRTVVEAYDAVAEDYADAYGGVAKPFERWLLTRVAELAGPHQLADVGAGPGDVTAFLAEAGAAPTGFDVSPRMVEVARQRHPELDFEVGDLRRLLRPGTAAGWGAVVSWFSLIHLAPSELTPAVRGLAETLLPDGVLALAVKTGNAVEQRSQWLGHDVRIAQVLHDPSAVLGAVRSAGLTDLEVYLTGEGQDRLYVIGRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ64</accession>
    <name>A0A1Q2CJ64_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_08505</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08505"/>
    <dbReference type="EnsemblBacteria" id="AQP46090">
        <property type="protein sequence ID" value="AQP46090"/>
        <property type="gene ID" value="RPIT_08505"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08505"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012026644" evidence="3">
        <location>
            <begin position="20"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP46090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="336" mass="33375" checksum="C687C46AC1068189" modified="2017-04-12" version="1">MVLGCVTAAAAWSPAHADASPGHCTSDSGVTVVVDFQELGGGTVVRCVDQVPAGTTGLQALRLAGFTHSGTIHDGPGFVCRIDDRPAATETLPVAGNEEYRETCVATPPKNAFWGYWHAPNGGEWTFSSFGGGARTVIPGGYEGWSFSLNRGTDSNPAPRVAPSHPVAPPATEPPAPPTTTTPPAPAPRPTTAAPGSTARPPANTATPASPPSSEPTTPDPAPEPARTAPIEAPSASPSPPAQPPISPSVDAPSPTTADSSPSTTAATGPAASPPPPRPSPGRSVPPGASLPPTTPAVVEAEPAAGPPLGTLIGVGAVVVLGAAGGATWWRRRGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJB6</accession>
    <name>A0A1Q2CJB6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_14755</name>
        <name evidence="10" type="ORF">SAMN05428934_10969</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPF0718 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14755"/>
    <dbReference type="EnsemblBacteria" id="AQP46194">
        <property type="protein sequence ID" value="AQP46194"/>
        <property type="gene ID" value="RPIT_14755"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05900">
        <property type="protein sequence ID" value="SDZ05900"/>
        <property type="gene ID" value="SAMN05428934_10969"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14755"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005524">
        <property type="entry name" value="DUF318"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03773">
        <property type="entry name" value="ArsP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP46194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ05900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="345" mass="36877" checksum="7F9812D0FF594D61" modified="2017-04-12" version="1">MSVVSAPTDRRLIGKLLGAVVIWALLYALNEVVWTALFERVLGLSLDDRLPGAIHFFLYDVSKILLLLVGMIFAIGLLRTTLRPERVRAFLDGKPILLSLLLAAVFGAVTPFCSCSSIPLFIGFVGAGIPLAVTLTFLIASPLVNEVAVALLAQTFGIGNTVAYMMAGLSAAVVIGFLLSRFKLDHLVADFVFATPVAALQMDGRKPTLQERVDAAREETADIFGRVWKWVILGVGIGAVIHGWVPTEFFARYAGPENPLAVVVATFAGIPLYANAAGVIPIAEALWSKGMALGTVMSFMMATVALSLPEFILLKQVLKPKLLAIFFSSVAAAILTIGLGFNIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJF3</accession>
    <name>A0A1Q2CJF3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GyrI-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13900"/>
    <dbReference type="EnsemblBacteria" id="AQP46180">
        <property type="protein sequence ID" value="AQP46180"/>
        <property type="gene ID" value="RPIT_13900"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13900"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029442">
        <property type="entry name" value="GyrI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06445">
        <property type="entry name" value="GyrI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GyrI-like" evidence="1">
        <location>
            <begin position="19"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="201" mass="22910" checksum="E454E5C682EA3580" modified="2017-04-12" version="1">MTDFKREIATYKAREGRFDVVTVAPLRFLMLDGEGDPNTAVGYRESLETLYPVAYKLKFFSKKELGRDFTVMPLEGLWWADDPAAFTSRRDKSLWRWTLLLMMPDWISAEHFDGARAAVAAKAPRVDALRLETFDEGRCVQTLHVGPYDDEGPVLAEMHERVIPDAGLAMTGKHHEIYLSDARRTAPAKLRTILRQPVREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBH9</accession>
    <name>A0A1Q2CBH9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-(apurinic or apyrimidinic site) lyase</fullName>
            <ecNumber evidence="3">4.2.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">RPIT_00385</name>
        <name evidence="18" type="ORF">SAMN05428934_10531</name>
    </gene>
    <organism evidence="17 19">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 19" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">RP1T</strain>
        </source>
    </reference>
    <reference evidence="18 20" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">RP1</strain>
        </source>
    </reference>
    <reference evidence="17" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPG family.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY84235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00385"/>
    <dbReference type="EnsemblBacteria" id="AQP43461">
        <property type="protein sequence ID" value="AQP43461"/>
        <property type="gene ID" value="RPIT_00385"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY84235">
        <property type="protein sequence ID" value="SDY84235"/>
        <property type="gene ID" value="SAMN05428934_10531"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00385"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019104">
        <property type="term" value="F:DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015886">
        <property type="entry name" value="DNA_glyclase/AP_lyase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012319">
        <property type="entry name" value="FPG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035937">
        <property type="entry name" value="MutM-like_N-ter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000214">
        <property type="entry name" value="Znf_DNA_glyclase/AP_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010663">
        <property type="entry name" value="Znf_FPG/IleRS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01149">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06831">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06827">
        <property type="entry name" value="zf-FPG_IleRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00898">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01232">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81624">
        <property type="entry name" value="SSF81624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51068">
        <property type="entry name" value="FPG_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51066">
        <property type="entry name" value="ZF_FPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="17" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="17" id="KW-0540">Nuclease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FPG_CAT" evidence="16">
        <location>
            <begin position="2"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="FPG-type" evidence="15">
        <location>
            <begin position="238"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="AQP43461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="SDY84235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="287" mass="30586" checksum="125E59B8CA66292A" modified="2017-04-12" version="1">MPELPEVAALAQALEEKLRGRVIAAGHLVSFSALKTYRIGLEALAGLEIGSVTRHGKFLDIEAQGIHLIFHLARAGWVKWHDEVPAVPARAGKSGLALRVVLDDGSGFSLTEAGTQKHLAVYIVEDPAEVPGIAALGPDPLAEGFTADDLGRILADAGRAQLKGVLRDQKTLAGIGNAYSDEILHAARLSPFKPANSLEKEGVDELYRHIRQVLGDAVVAASGHPIEELKDAKRASMRVHGRTGEQCDECGTTIAEVSFVDSSLQYCPGCQTGGKPLADRRLSKLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBI5</accession>
    <name>A0A1Q2CBI5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA synthetase</fullName>
            <shortName evidence="7">SerRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA(Ser/Sec) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">serS</name>
        <name evidence="9" type="ORF">RPIT_00430</name>
        <name evidence="10" type="ORF">SAMN05428934_10540</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl-tRNA(Sec)</text>
            <dbReference type="Rhea" id="RHEA:42580"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:10128"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl-tRNA(Ser)</text>
            <dbReference type="Rhea" id="RHEA:12292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9669"/>
            <dbReference type="Rhea" id="RHEA-COMP:9703"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer. The tRNA molecule binds across the dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY84495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00430"/>
    <dbReference type="EnsemblBacteria" id="AQP43469">
        <property type="protein sequence ID" value="AQP43469"/>
        <property type="gene ID" value="RPIT_00430"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY84495">
        <property type="protein sequence ID" value="SDY84495"/>
        <property type="gene ID" value="SAMN05428934_10540"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00430"/>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097056">
        <property type="term" value="P:selenocysteinyl-tRNA(Sec) biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00176">
        <property type="entry name" value="Ser_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11778">
        <property type="entry name" value="PTHR11778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="139"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Serine binding" evidence="7">
        <location>
            <begin position="230"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="261"/>
            <end position="263"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="348"/>
            <end position="351"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="382"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP43469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY84495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="422" mass="46585" checksum="D8F11FABE8443CB9" modified="2017-04-12" version="1">MIDPKWLRSDPDRIRRSQAARGASVELVDELIAADEARRASILTSEQLRAEQKSLGKQVARAQGEEKQELLSRTKQLAADVKTTQGATVEAEAKFDDLMKQLGNLVLDGVPEGGEDDGVVIETIGTPRDFAAEGFEPRDHLELGEKLGAIDMERGTKISGSRFYVLTGVGAQLEIALLNLAMAKATEWGFTPMIPPALVKPSAMEGTGFLGQAAQDVYHLEADDLYLVGTSEVALAAYHAGEILDAGTLPRQYVAYSPCFRREAGSYGKDTRGIFRVHWFDKVEMFVHCDPADAEDWHQKLLGFEKEFLTALEVPFQVLDVASGDLGLSAARKYDCYAWLPTQQRYREVTSTSNCTEFQARRLGIRARFDDGVRPVATLNGTLCAMTRIIIMLLENHQQADGSIHVPEALRPYLGGRERLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBL8</accession>
    <name>A0A1Q2CBL8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hexapeptide repeat of succinyl-transferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00580</name>
        <name evidence="2" type="ORF">SAMN05428934_10569</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY85248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00580"/>
    <dbReference type="EnsemblBacteria" id="AQP43497">
        <property type="protein sequence ID" value="AQP43497"/>
        <property type="gene ID" value="RPIT_00580"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY85248">
        <property type="protein sequence ID" value="SDY85248"/>
        <property type="gene ID" value="SAMN05428934_10569"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00580"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY85248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="198" mass="20951" checksum="A6743D839D7B324D" modified="2017-04-12" version="1">MVRIQDSADVSPDAVIGEGSSIWHLAQVREGAVLGENCIVGRGAYVGTGVKMGDNCKLQNYALVYEPAELEDGVFVGPAVVFTNDHFPRSIDPDGKLKRGDDWEPVGVTCKKGSSIGARAVCVAPVTIGSWAMVAAGAVVTKDVPDFALVAGVPAKRIRWVGRAGVPLERGDAEGLWVCPQTGAQYQEQDETLVEVTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBM5</accession>
    <name>A0A1Q2CBM5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP-dependent 6-phosphofructokinase</fullName>
            <shortName evidence="9">ATP-PFK</shortName>
            <shortName evidence="9">Phosphofructokinase</shortName>
            <ecNumber evidence="9">2.7.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Phosphohexokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pfkA</name>
        <name evidence="11" type="ORF">RPIT_00675</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer or homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.11" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00675"/>
    <dbReference type="EnsemblBacteria" id="AQP43514">
        <property type="protein sequence ID" value="AQP43514"/>
        <property type="gene ID" value="RPIT_00675"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00675"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047334">
        <property type="term" value="F:diphosphate-fructose-6-phosphate 1-phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01976">
        <property type="entry name" value="Phosphofructokinase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012003">
        <property type="entry name" value="ATP_PFK_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012829">
        <property type="entry name" value="Phosphofructokinase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000532">
        <property type="entry name" value="ATP_PFK_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="SSF53784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFK" evidence="10">
        <location>
            <begin position="11"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="140"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="184"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="304"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="81"/>
            <end position="82"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for substrate specificity; cannot use PPi as phosphoryl donor" evidence="9">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP43514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="380" mass="39384" checksum="5B46E0A67D30A23A" modified="2017-04-12" version="1">MESWEQAMAKRVGILTAGGDSPGLNAAIRGFGKAAIGQHGMELIGFEQGIRGLAEDRWRVLDSAALSGILTVGGTVLGTSRDKPHRMVIDGETVDMVPTIVENYEKNKLDALVCIGGGGTAKNANRLAKAGLNVIHLPKTIDNDIAHTDTSFGFSTALGIATDAIDRLHSTAHSHHRVIIAEIMGHKAGWLALGSGVAGGADIILIPEIPYSIESVAESVHSRAKSGRSFSVIAIAEGARDEQDTADLAAAEALRKSASAPEEKAAATKHRDSIEAAHRDNAFKVASALEEATGLESRVTILGYVQRGGTPDAHDRMLGTLLGSAGAALVADKEFGITVASQSGEAVPVPLSDVAGNLKTVPVDHAWIKAARAVGTGLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBP7</accession>
    <name>A0A1Q2CBP7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Hippurate hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00750</name>
        <name evidence="3" type="ORF">SAMN05428934_105103</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00750"/>
    <dbReference type="EnsemblBacteria" id="AQP43528">
        <property type="protein sequence ID" value="AQP43528"/>
        <property type="gene ID" value="RPIT_00750"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86172">
        <property type="protein sequence ID" value="SDY86172"/>
        <property type="gene ID" value="SAMN05428934_105103"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00750"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014">
        <property type="entry name" value="PTHR11014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005962">
        <property type="entry name" value="Pept_M20D_amidohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="183"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY86172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="389" mass="41801" checksum="5EBC5F2727E2BD19" modified="2017-04-12" version="1">MIDLIAVRRELHQIPEVGLDLPRTQEAVLKALDGLPLEITLGESLTSVVGVLRGGRETQGKRPVVLLRADMDALPVKELTGLDYASTNGNMHACGHDLHMTMLIGAAHELCARRGELAGDVIFMFQPGEEGVDGARYMLEEGLLDVAGPRPDYVYAIHVWSALDPHGVFSTKPGTVMASSDIAKVRVLGRGGHGSTPQLAADPVPALAAITTGLNTMVTRNFDVQNPVVVTVGLLSAGTIANVIPEEGRLEATLRTFDTDVRAKLFQTIERLVDGIAAGHGVTGETEFVEQYPVTVNHDAEADVVADVVRDLFGDERHRRWEKPLAGAEDFSRLLEEVPGCFIGLSACPPDADPDTAPFNHSAYARFDDAVVPDGARLFAELALRKLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBQ5</accession>
    <name>A0A1Q2CBQ5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00820</name>
        <name evidence="3" type="ORF">SAMN05428934_105117</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43539">
        <property type="protein sequence ID" value="AQP43539"/>
        <property type="gene ID" value="RPIT_00820"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86528">
        <property type="protein sequence ID" value="SDY86528"/>
        <property type="gene ID" value="SAMN05428934_105117"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00820"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY86528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="97" mass="9968" checksum="E8F931F1A8B3F53A" modified="2017-04-12" version="1">MAEPPSKRSRRWVYAAAAAAAAVIAIVFTVVGDGVAATESAGWLGVVVDWGHQLVWALLAAAFTVAAVRDGWTKPSQILAVGALALYAAFLAAVFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBU8</accession>
    <name>A0A1Q2CBU8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Carbohydrate ABC transporter membrane protein 2, CUT1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_01070</name>
        <name evidence="7" type="ORF">SAMN05428934_105165</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01070"/>
    <dbReference type="EnsemblBacteria" id="AQP43584">
        <property type="protein sequence ID" value="AQP43584"/>
        <property type="gene ID" value="RPIT_01070"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87832">
        <property type="protein sequence ID" value="SDY87832"/>
        <property type="gene ID" value="SAMN05428934_105165"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01070"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="79"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="79"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY87832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="295" mass="32618" checksum="B6EE3279574C8509" modified="2017-04-12" version="1">MSATTEASTRKRSTPPARIALQIGLVIISLVWLFPLLWALFNSFRDYSYTVQNGYLSFGGFTFDNYINAWNRGGFTNSFLNSAIITITAVVLTLALSSCAAFVLARYSFKFNLAMLAVFVSANLLPPQSLLIPVYRMFRTIEVPLWLSESGSLLDSHLGVILINVAFQTGFTTFVLSNYMKTFPKEIYESASLDGATAWRQFYGLTLPLLRPPMAALGTLQTAWIYNEFFWATVLMQSGDKFPVTSSLNNLKGSFFTDYNLLSAGSIIAALPVLVVFFVLQKQFIAGLTLGATKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC04</accession>
    <name>A0A1Q2CC04_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">LysR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01385</name>
        <name evidence="3" type="ORF">SAMN05428934_10824</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01385"/>
    <dbReference type="EnsemblBacteria" id="AQP43632">
        <property type="protein sequence ID" value="AQP43632"/>
        <property type="gene ID" value="RPIT_01385"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01362">
        <property type="protein sequence ID" value="SDZ01362"/>
        <property type="gene ID" value="SAMN05428934_10824"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01385"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02199">
        <property type="entry name" value="YjgF_YER057c_UK114_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013813">
        <property type="entry name" value="Endoribo_LPSP/chorism_mut-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14588">
        <property type="entry name" value="YjgF_endoribonc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjgF_endoribonc" evidence="1">
        <location>
            <begin position="5"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ01362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="155" mass="15551" checksum="82045922E7C9F8A6" modified="2017-04-12" version="1">MTVSARLAELGLQLPPVARPVAAYVPAARVGSQIWTSGQLPTVDGALVATGKLGEALSVDDGVDAARTATLNALAAVSDVAGGIDRIRSIVKVVVYVASDSGFTQQPAVANGASNLLGDLFGPSGAHVRSAVGVSVLPLDAPVEIELIVEADELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC11</accession>
    <name>A0A1Q2CC11_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cell fate regulator YaaT, PSP1 superfamily (Controls sporulation, competence, biofilm development)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01485</name>
        <name evidence="3" type="ORF">SAMN05428934_10845</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01485"/>
    <dbReference type="EnsemblBacteria" id="AQP43649">
        <property type="protein sequence ID" value="AQP43649"/>
        <property type="gene ID" value="RPIT_01485"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01801">
        <property type="protein sequence ID" value="SDZ01801"/>
        <property type="gene ID" value="SAMN05428934_10845"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01485"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007557">
        <property type="entry name" value="PSP1_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04468">
        <property type="entry name" value="PSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51411">
        <property type="entry name" value="PSP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PSP1 C-terminal" evidence="1">
        <location>
            <begin position="57"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ01801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="286" mass="31205" checksum="EC941D8BD7A28F9E" modified="2017-04-12" version="1">MARVMAVAFERHGQLHYLDPADGAYAVGDWVRYPTPDGPEIAQVVWAAEDVEGFDDVPVCQGPATQADHARDAANRQRRADAMAVAKRTIAGHGLPMKVVGVDYLDRTAEFDRLIAIYYTAPHRVDFRSLLGDLARALDSRIDLRQVGSRDAARLIGGVGSCGRELCCTTFLTDFEPVSTRLARVQGLPPNPLQISGQCGRLMCCLKYEHPLYVDFIKQAPAIGDRVTVDGQEMTVTGHNVPAGSVTGRTPSGEMVRCPLEKVCSAKMSRDLRSANVKLSEKGEHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC26</accession>
    <name>A0A1Q2CC26_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amine oxidase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">UDP-galactopyranose mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01500</name>
        <name evidence="3" type="ORF">SAMN05428934_10848</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01500"/>
    <dbReference type="EnsemblBacteria" id="AQP43650">
        <property type="protein sequence ID" value="AQP43650"/>
        <property type="gene ID" value="RPIT_01500"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01844">
        <property type="protein sequence ID" value="SDZ01844"/>
        <property type="gene ID" value="SAMN05428934_10848"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01500"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ01844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="449" mass="47932" checksum="56A8D26B8B3C273E" modified="2017-04-12" version="1">MLDCAIIGAGLAGLVAAQHLADRGLKVVVLEARDRVGGRVENKTLSDGSYVELGGQWIGPGFDALLEIIDGLGLETIGLPAAGNLAIRLRGKSLSVPSSEDGRTLTPFEVSDLGQGLLRLRRLAKRLRDDPAWRKANDAWLGQDLRRWVSTNLRTEGAQRRFAEVYQAAFGAMPKGATLLGGLHQVNSGPDLESMLASNGGLHQKRVAGGMAAVADALAEKLGGVVRLGKEVVRVEHDDASARIILADGEVIEAKQVISTLPPRLAVALPHEPALPDWRAEAADKVSAGNVIKAFLIYERPFWRELGLSGQSSADEGAVRVTFDTTAGDSERGHLMGFFEGADAASLARRSSTLRERAFVDSVVRTFGEVARNPVTYIERDWASEKFTGGCHGAHFAPGVWTTQGPVLARPEGVLHWAGAEYASRFNGYLEGAVRSGREVAAAVARNLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC49</accession>
    <name>A0A1Q2CC49_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CAAX protease family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">CAAX protease self-immunity</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01675</name>
        <name evidence="3" type="ORF">SAMN05428934_10884</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01675"/>
    <dbReference type="EnsemblBacteria" id="AQP43677">
        <property type="protein sequence ID" value="AQP43677"/>
        <property type="gene ID" value="RPIT_01675"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02509">
        <property type="protein sequence ID" value="SDZ02509"/>
        <property type="gene ID" value="SAMN05428934_10884"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01675"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ02509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="253" mass="27903" checksum="378E24D11BA346DB" modified="2017-04-12" version="1">MRMHRLRWEIVVVLAISLGQSAVYAVLSIIEKMTRPTPLNQQTTSMNRSAVPDRPWLDLAYQVAGVVFPLMPVVLVLFLMAIHVRPPDGPARTMGFDLKRPAFDLAWGFGVFAVIGVAGLAFYLFAVTIGINTQVSPANLAANWWTVPVLLARAVMNGVLEEVVMVGYLFTRWAQTGGRMWVIVVLSAVVRGGYHLYQGWGGFIGNLVMGLAFGWLYLRIKRVMPLVITHSLLDIVAFLGAPLLPVLMAMVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC84</accession>
    <name>A0A1Q2CC84_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADH dehydrogenase subunit D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01605</name>
        <name evidence="4" type="ORF">SAMN05428934_10869</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01605"/>
    <dbReference type="EnsemblBacteria" id="AQP43665">
        <property type="protein sequence ID" value="AQP43665"/>
        <property type="gene ID" value="RPIT_01605"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02243">
        <property type="protein sequence ID" value="SDZ02243"/>
        <property type="gene ID" value="SAMN05428934_10869"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01605"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001135">
        <property type="entry name" value="NADH_Q_OxRdtase_suD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022885">
        <property type="entry name" value="NDH1_su_D/H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993">
        <property type="entry name" value="PTHR11993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00346">
        <property type="entry name" value="Complex1_49kDa"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="SSF56762"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0874">Quinone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex1_49kDa" evidence="2">
        <location>
            <begin position="148"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Complex1_49kDa" evidence="2">
        <location>
            <begin position="291"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ02243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="367" mass="39598" checksum="BF683DDDB6CBD467" modified="2017-04-12" version="1">MDKQYTIGGLSLPGHDSLSLGPRHPTSVGLIRLSLHTDNGVISHADVTSGFGHRAAEKLFEVRDYRSMIMLADRHDWLAAFSGELSLTLTVENALRLTPPPRATVLRTLLAEYARLHSHLSFLSYLADGELEARLWACVEGLRQGLLTWTGNRVHPMLARVGGLAADVPAGWLDALDDLLDDVARVSSDLRGVLARTDRFSGLAVLDAEACLSYGLSGPVSRAADLDLDRRYTGYLAYGELHRPVQTRDAGDAQARFGVLIDELGTSIDMIRMARALAGETPGDVDVRLSRRLKVPEGEHQTQIEAPWGVAGCLMVSRGGQTPWRVALRTPSFANLSALGAALSGAPEEQICDVVASLGYTIGDADK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC90</accession>
    <name>A0A1Q2CC90_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative Holin-X, holin superfamily III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01885</name>
        <name evidence="4" type="ORF">SAMN05428934_108125</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ03343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43711">
        <property type="protein sequence ID" value="AQP43711"/>
        <property type="gene ID" value="RPIT_01885"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ03343">
        <property type="protein sequence ID" value="SDZ03343"/>
        <property type="gene ID" value="SAMN05428934_108125"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01885"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544401" evidence="2">
        <location>
            <begin position="26"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ03343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="75" mass="8349" checksum="8D4BA707B42FA298" modified="2017-04-12" version="1">MTTKRLVTALVVVLVGFMVATVAIAFGQDDIDWGWWWAVPLGGFFVLVVLGFRVLVQRSQEAAERADREADEPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCD2</accession>
    <name>A0A1Q2CCD2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal subunit assembly factor BipA</fullName>
            <ecNumber evidence="2">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">GTP-binding protein BipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">bipA</name>
        <name evidence="4" type="ORF">RPIT_01845</name>
        <name evidence="5" type="ORF">SAMN05428934_108117</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">Binds to ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ03186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01845"/>
    <dbReference type="EnsemblBacteria" id="AQP43705">
        <property type="protein sequence ID" value="AQP43705"/>
        <property type="gene ID" value="RPIT_01845"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ03186">
        <property type="protein sequence ID" value="SDZ03186"/>
        <property type="gene ID" value="SAMN05428934_108117"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01845"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03710">
        <property type="entry name" value="BipA_TypA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00849">
        <property type="entry name" value="BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035651">
        <property type="entry name" value="BipA_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042116">
        <property type="entry name" value="TypA/BipA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006298">
        <property type="entry name" value="TypA_GTP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF8">
        <property type="entry name" value="PTHR42908:SF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01394">
        <property type="entry name" value="TypA_BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Tr-type G" evidence="3">
        <location>
            <begin position="5"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="17"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="135"/>
            <end position="138"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ03186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="620" mass="68084" checksum="4CC64723E6E9FF13" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCH8</accession>
    <name>A0A1Q2CCH8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">ABC-type lipoprotein export system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_02355</name>
        <name evidence="7" type="ORF">SAMN05428934_10171</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY24420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02355"/>
    <dbReference type="EnsemblBacteria" id="AQP43801">
        <property type="protein sequence ID" value="AQP43801"/>
        <property type="gene ID" value="RPIT_02355"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY24420">
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_tran"/>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="22"/>
            <end position="261"/>
        </location>
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        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="58"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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        <source>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP43801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY24420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="314" mass="34015" checksum="97383995E2930602" modified="2017-04-12" version="1">MTELSARRALAAAERTHAGPDIWCEDLVRIHVTDGIEVQALQGLSLTVDPGEVVAVVGASGSGKSTLLNILSGLDKPTGGRARVAGQDLGTLNRRQRIDFRRHTVGFVFQQTSRNLLPFLTAAENVAMPMVIANRAGRRQRARDLLDLLEVADVAGRRPGQLSGGQQQRVAIATALANSPAVLLADEPTGELDETNSASVLEIMRAAATEVGTTVLIVTHDPTVSEHVARTVQIRDGRTSTEVLRRTERGADGVEREIAEEYSVIDRNGRLQLPSTHVDELGLRERVRVSREDDHVGVWPDTPSARRGVEEDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCK0</accession>
    <name>A0A1Q2CCK0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA-binding transcriptional regulator, MarR family</fullName>
        </submittedName>
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    <gene>
        <name evidence="2" type="ORF">RPIT_02400</name>
        <name evidence="3" type="ORF">SAMN05428934_10178</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02400"/>
    <dbReference type="EnsemblBacteria" id="AQP43810">
        <property type="protein sequence ID" value="AQP43810"/>
        <property type="gene ID" value="RPIT_02400"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY24633">
        <property type="protein sequence ID" value="SDY24633"/>
        <property type="gene ID" value="SAMN05428934_10178"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY24633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="144" mass="15662" checksum="10121AF940DCBA0E" modified="2017-04-12" version="1">MPDFDSDLLTLANDLRVACQRIARRVRFESTSDVAPHLFSVLVGLHNDGPQTPTQLAGRDSVSTPSMTRSVNCLADKGLVERLPHPDDGRQILVQLTDGGRTVIDETIASRDTWMLHHIAGLAPDQLALLRQAADLLSEVASAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCK1</accession>
    <name>A0A1Q2CCK1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Galactokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_02550</name>
        <name evidence="10" type="ORF">SAMN05428934_101110</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY25555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02550"/>
    <dbReference type="EnsemblBacteria" id="AQP43834">
        <property type="protein sequence ID" value="AQP43834"/>
        <property type="gene ID" value="RPIT_02550"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY25555">
        <property type="protein sequence ID" value="SDY25555"/>
        <property type="gene ID" value="SAMN05428934_101110"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02550"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004335">
        <property type="term" value="F:galactokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000705">
        <property type="entry name" value="Galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019539">
        <property type="entry name" value="GalKase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006206">
        <property type="entry name" value="Mevalonate/galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10457:SF6">
        <property type="entry name" value="PTHR10457:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10509">
        <property type="entry name" value="GalKase_gal_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000530">
        <property type="entry name" value="Galactokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00473">
        <property type="entry name" value="GALCTOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="3 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GalKase_gal_bdg" evidence="8">
        <location>
            <begin position="3"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_N" evidence="6">
        <location>
            <begin position="92"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="7">
        <location>
            <begin position="290"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP43834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY25555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="397" mass="42102" checksum="49EBA032CA3DFA55" modified="2017-04-12" version="1">MKWFVPGRLEVLGKHTDYAGGRSLLAAVDRGVTITLEDADEAIAASTTAVPGRLRLLPGVEPGLPQGHWGYYVQAVLDRLHLNFGDLKPASLLFDSNLPLASGMSSSSALVVAAALALIDHNGIRDTDEWKANIRTDIDLAGYLATMENGLTFGALEGFRGVGTFGGSEDHTAMLCCKADHLTEFTFCPIEEQRSVQFPADWTFVVAVSGVLAEKTGSALESYNNASRKARELAEAWNSATGRDDAVLGDALASSDDALEGLRAISAHDDALTARLTAFVTESEVAIPRAIDALERGDIKGFGEAAELSHRNADEALGNQIDETNRLQWLARELGAPAAAGFGAGFGGSVWALVETAEAESFADRWLAAYLAEFPAVEGRASTIVTRPGGPARRLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCN5</accession>
    <name>A0A1Q2CCN5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02825</name>
        <name evidence="3" type="ORF">SAMN05428934_101165</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY27129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02825"/>
    <dbReference type="EnsemblBacteria" id="AQP43878">
        <property type="protein sequence ID" value="AQP43878"/>
        <property type="gene ID" value="RPIT_02825"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY27129">
        <property type="protein sequence ID" value="SDY27129"/>
        <property type="gene ID" value="SAMN05428934_101165"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02825"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014">
        <property type="entry name" value="PTHR11014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="183"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY27129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="388" mass="40392" checksum="09A037BEAE7CD671" modified="2017-04-12" version="1">MTGELLRGLVAGIDRALPHAAALRREIHANPSLSGHEEPTRAAFIDAADHLHWREVAHTGAWARMGPDGPAVGVRAELDALPINESTGVEWESKVAGVMHACGHDLHLAALWALTEAARDVDLPVGLVPILQPREEITPPGAGDVVASGLIEDEQIEAMIGVHVQPAVERGVVSTGTGAVNAGYDSFEIVVKGRPGHGAYPHIAIDPITTLADIVGALSGLPTRVIDPIRPTVISVGQISGGTAPNVIADEASCRGTIRTFTEADRDLLHEAITRTAESIALGRGALATTRFVRGGPPLVNDPGLAHRVDRELSSLGITVAETPFRSCGSDDFAEYGLATASVMCFVGTGRIDGIGLHHGAFLPGREALQLAAHTMAAGYVAAAGMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCR9</accession>
    <name>A0A1Q2CCR9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Monosaccharide ABC transporter ATP-binding protein, CUT2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_02930</name>
        <name evidence="6" type="ORF">SAMN05428934_101187</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY27840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02930"/>
    <dbReference type="EnsemblBacteria" id="AQP43896">
        <property type="protein sequence ID" value="AQP43896"/>
        <property type="gene ID" value="RPIT_02930"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY27840">
        <property type="protein sequence ID" value="SDY27840"/>
        <property type="gene ID" value="SAMN05428934_101187"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02930"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="261"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY27840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="511" mass="55915" checksum="9092F4E08BCEC2C0" modified="2017-04-12" version="1">MSDIILEMRNITKEFPGVKALSNVNLSVERGEIHAICGENGAGKSTLMKVLSGVYPHGTYDGEIFFDGETVKFNSINQSEAKGIVIIHQELALVPTLSIAENIFLGNEQREQGHINWNRTNQKAAQLLARVGLDENPTTLIQDIGVGKQQLVEIAKALSKEVKLLILDEPTAALNDTDSAHLLGLLRQLKEQGITSIMISHKLNEIIAISDATTIIRDGMTIETLSRGPEMSQERIIKGMVGRDLEHLYPEHTPSIGEELFRVEDWSVMHPTIPGRRSIDGASFNVRAGEIVGIAGLMGAGRTELAMSVFGQAWGHKVSGKAFLHGKELNLSSVHEAIRAGLAYATEDRKRFGLNLIDDIRRNISAASLDRIKTPLGAVNANEEIKRAEEFRGSMRIKTPSVMALAGQLSGGNQQKVVLSKWMMTEPEVLILDEPTRGIDVGAKYEIYTIINQLADAGKGVIVISSELPELLGICDRIYTLAFGRITGVLDRADATQENLMTLMTKEREAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCS0</accession>
    <name>A0A1Q2CCS0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Monosaccharide ABC transporter substrate-binding protein, CUT2 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Sugar ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_02935</name>
        <name evidence="5" type="ORF">SAMN05428934_101188</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY27862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02935"/>
    <dbReference type="EnsemblBacteria" id="AQP43897">
        <property type="protein sequence ID" value="AQP43897"/>
        <property type="gene ID" value="RPIT_02935"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY27862">
        <property type="protein sequence ID" value="SDY27862"/>
        <property type="gene ID" value="SAMN05428934_101188"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02935"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544421" evidence="2">
        <location>
            <begin position="33"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="3">
        <location>
            <begin position="54"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY27862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="382" mass="40347" checksum="C6393B219648E192" modified="2017-04-12" version="1">MNINRRGFIGLGAVSAAAIGLVACGGDETPGATTAPTTATGGETSAPAGAGGKVGVSMPTQTSERWIADGEAVQQQLQDAGFEVDLQFANDDIPTQSQQVDQMITQGVKVLIIAAIDGTALAPQLDAAAAAGIKVISYDRLIRDSENVDFYVSFDNFKVGVAQGQSLIDGLAERFPDENPANIELFAGSLDDNNAHFFFSGAMSVLQPKIDAGEFVVQSEQTSIEQAAILRWQQETAQKRMEDLLTAHYGDKKVHGVLSAYDGLSRGIITALENGGYSGETFPIVTGQDAEIASVKLIVDGVQYSTIFKDTRLLAEQAVKAAVALLEGNEPEANDTETYDNGVKVVPSYLLDVTTVTDDNVVEALVDTGYWTQAEVDSGVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCS3</accession>
    <name>A0A1Q2CCS3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02980</name>
        <name evidence="3" type="ORF">SAMN05428934_101197</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY28142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43904">
        <property type="protein sequence ID" value="AQP43904"/>
        <property type="gene ID" value="RPIT_02980"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY28142">
        <property type="protein sequence ID" value="SDY28142"/>
        <property type="gene ID" value="SAMN05428934_101197"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02980"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY28142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="76" mass="8130" checksum="BC5059DA4A3F4CB9" modified="2017-04-12" version="1">MKTTIDIPDALAVRAKRFVASGGPGTTLRDLVIAGLEAELNRRERPARVDFNWVTQDGQGLAQPQASTTDRPGGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCT3</accession>
    <name>A0A1Q2CCT3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">RNA helicase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">Superfamily II DNA and RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_03135</name>
        <name evidence="11" type="ORF">SAMN05428934_101228</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03135"/>
    <dbReference type="EnsemblBacteria" id="AQP43933">
        <property type="protein sequence ID" value="AQP43933"/>
        <property type="gene ID" value="RPIT_03135"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29105">
        <property type="protein sequence ID" value="SDY29105"/>
        <property type="gene ID" value="SAMN05428934_101228"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03135"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="9">
        <location>
            <begin position="4"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="35"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="221"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="382"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="4"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="409"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP43933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY29105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="482" mass="51004" checksum="5470C30E1EF779C5" modified="2017-04-12" version="1">MTSSAFRALGVPTHLAAVLEARGITTPTPIQAATLPDSMSGRDVLGRGRTGSGKTYAFLLPMVARLTESGTKRAPKRPRALILAPTRELATQIDEALAPLAEAAGLTSRTIFGGVNQRPQVAALTRGVDVLVACPGRLEDLIAQGFVTLNAIEITILDEADHMADLGFLPSVRRLLGATPQTGQRMLFSATLDKAVDTLVKQFLHQPKVHEADSAESPVPTLHHHVLHVSNDAHLPVLVNLAAAPGRSVVFTRTKHRAKKLAKQLNAAGVPAVELQGNMSQGQRERSMAAFHAGTAQTLVATDVAARGIHVDDVGLVIHADPPVEHKAYTHRSGRTARAGAEGTVVTLMLDAQRSDVRDLTRKAGVKPTITRADERHPVLVEIAPGERTFPGGLVKPEPQQPTGGRRRNPAGDRSRGAEQGRGANRTEGRAQSRSERPRGAAQGDAPSGRRQGQPRSRSAQPVGTGGAAAFSASTGRGRGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCV8</accession>
    <name>A0A1Q2CCV8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NPCBM-associated, NEW3 domain of alpha-galactosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_03240</name>
        <name evidence="5" type="ORF">SAMN05428934_101249</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43949">
        <property type="protein sequence ID" value="AQP43949"/>
        <property type="gene ID" value="RPIT_03240"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29777">
        <property type="protein sequence ID" value="SDY29777"/>
        <property type="gene ID" value="SAMN05428934_101249"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03240"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016137">
        <property type="term" value="P:glycoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010502">
        <property type="entry name" value="Carb-bd_dom_fam9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06452">
        <property type="entry name" value="CBM9_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544428" evidence="2">
        <location>
            <begin position="27"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="domain" description="Carb-bd_dom_fam9" evidence="3">
        <location>
            <begin position="584"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY29777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="1151" mass="122379" checksum="0BB131C8EABEA803" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCZ1</accession>
    <name>A0A1Q2CCZ1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">S-(Hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03330</name>
        <name evidence="3" type="ORF">SAMN05428934_101267</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03330"/>
    <dbReference type="EnsemblBacteria" id="AQP43966">
        <property type="protein sequence ID" value="AQP43966"/>
        <property type="gene ID" value="RPIT_03330"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30337">
        <property type="protein sequence ID" value="SDY30337"/>
        <property type="gene ID" value="SAMN05428934_101267"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03330"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="ADH-like_C"/>
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        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
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    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
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    </dbReference>
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        <property type="entry name" value="PKS_ER"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
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    </dbReference>
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        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="17"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY30337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="378" mass="40236" checksum="E67BA2458990748C" modified="2017-04-12" version="1">MSSQTIPNLMRAAVLRDVSRGFAVEEIRTPRPKEGEILIQVSACGMCHSDLHVLGGAISFPTPCVLGHEVAGVVVEIGPHNEHTTLKVGDRVAGAFLMPCGQCESCAAGRDDLCSNFFSLNRLKGQLYDGNTRLFSRDGEPIWMYSMGGLAEYCVIPTTSAAKLPDGVDPVAGAILGCAAMTAYGAVRRGADLRHGEDVAVVATGGVGSNVIQIARAFGARRVIAIDISDEKLTDAMGLGATHAVNSATTDVREAVFDITEGRGVDVAFEVLGRPETWLTALDALRDGGRMVPIGLGAGIQKAEVEINRTVRRSQSIIGSYGARTRLDLPEVVRMAASGVIDYRHIVSRRFSLDEVAEGYDLLHHGKIRGRAVVDLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCZ8</accession>
    <name>A0A1Q2CCZ8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNB domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03465</name>
        <name evidence="3" type="ORF">SAMN05428934_101293</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY31156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03465"/>
    <dbReference type="EnsemblBacteria" id="AQP43989">
        <property type="protein sequence ID" value="AQP43989"/>
        <property type="gene ID" value="RPIT_03465"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY31156">
        <property type="protein sequence ID" value="SDY31156"/>
        <property type="gene ID" value="SAMN05428934_101293"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03465"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040596">
        <property type="entry name" value="RNase_II_C_S1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18614">
        <property type="entry name" value="RNase_II_C_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNB" evidence="1">
        <location>
            <begin position="51"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY31156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="477" mass="52697" checksum="63950444152C7C0F" modified="2017-04-12" version="1">MPSTHLDIRDIPEDLRQGLIDLQSRLGLPREFPAEVAAEAELAAQLPPESHEDFTEIEFVTIDPPSSQDLDQALQIERDGDGYLVRYAISDVAHFVRAGTALEAETHRRGQTLYAPSARIPLHPPALSEDAASLLADGQPRPAMVWEHRLNRDGELTEVSLTRAMVVSRAKLNYEGVQADLDAGRAHPSVELLPEVGLKRQQLEIERGGISLNLPEQEIVEHGHTWDLEFRALVPVENYNAQISLLTGFAAAQTMLEGKVGILRTLPPAEDWSIAKLRRSVRSLGVEWPTSMPYPEFVRSLSPERPEELAALTKCTMLFRGAGYLSFDGEVPDENLLHAALAAPYAHTTAPLRRLVDRYVLEICHSLLNGIDVPQWAREDLAVLPKEMSDSGRTARAYENGVVDLTEALVMRDRVGQIFTGVLTDVHPKTGVGTVQIPDPAVELRVGAKQKEVGSEIRVRVDKVDVRAGRVTLSRPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD07</accession>
    <name>A0A1Q2CD07_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Superoxide dismutase</fullName>
            <ecNumber evidence="2 6">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_03415</name>
        <name evidence="10" type="ORF">SAMN05428934_101283</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 H(+) + 2 superoxide = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="2 6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03415"/>
    <dbReference type="EnsemblBacteria" id="AQP43981">
        <property type="protein sequence ID" value="AQP43981"/>
        <property type="gene ID" value="RPIT_03415"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30841">
        <property type="protein sequence ID" value="SDY30841"/>
        <property type="gene ID" value="SAMN05428934_101283"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03415"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="SSF46609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="SSF54719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sod_Fe_N" evidence="7">
        <location>
            <begin position="2"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Sod_Fe_C" evidence="8">
        <location>
            <begin position="90"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP43981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY30841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="204" mass="22570" checksum="6F4D5649B3C1AB9C" modified="2017-04-12" version="1">MTYTLPDLDYDYGALAPHIAPEIMELHHSKHHAAYVKGINDALEQLAAARDKGDLGAVNKLSKDAAFHLGGHINHSVFWKNMSPDGGGEPDGDIAAALDEYFGSFDGFKKHFNAVANGIQGSGWSMLVWDTLGQRLNINQLFDQQGNLPAGQIPVLQLDMWEHAFYLQYKNVKGDYVNAWWNVVNWTDVNERFAKAKAASDALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD12</accession>
    <name>A0A1Q2CD12_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phage shock protein A</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Phage shock protein A (PspA) family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_03615</name>
        <name evidence="5" type="ORF">SAMN05428934_101324</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PspA/IM30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY32066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03615"/>
    <dbReference type="EnsemblBacteria" id="AQP44013">
        <property type="protein sequence ID" value="AQP44013"/>
        <property type="gene ID" value="RPIT_03615"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY32066">
        <property type="protein sequence ID" value="SDY32066"/>
        <property type="gene ID" value="SAMN05428934_101324"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03615"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007157">
        <property type="entry name" value="PspA_IM30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31088">
        <property type="entry name" value="PTHR31088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04012">
        <property type="entry name" value="PspA_IM30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="230"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="55"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY32066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="259" mass="28451" checksum="997EDBB7675FC117" modified="2017-04-12" version="1">MASIFERIALVFKSKANKTLDKYEDPRETLDYSYQKQLELLQNVRRGVADVATSRKRVELQASKLNSEVERLQSAAQRALESNREDLAREALTRKAGLQTQLDDLQTQHAQLQGEEEKLVRASSRLQAKVDAFRTRKETIKATYSAAEAQTRINEAFTGISEEMSDVGLAIQRAEDKTLQLQARASAVDELLASGALEDPTGTVKDDITRELDMLAADSTVESELAAMKAQLTGGPAARPEIESAPAAQESGDTQGRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD43</accession>
    <name>A0A1Q2CD43_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Iron-sulfur cluster insertion protein ErpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03630"/>
    <dbReference type="EnsemblBacteria" id="AQP44016">
        <property type="protein sequence ID" value="AQP44016"/>
        <property type="gene ID" value="RPIT_03630"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03630"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="FeS_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="FeS_cluster_insertion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="SSF89360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00049">
        <property type="entry name" value="TIGR00049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S_biosyn" evidence="1">
        <location>
            <begin position="17"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="119" mass="12843" checksum="102C855E7E299092" modified="2017-04-12" version="1">MEPSVTDTQTTQSGVVLTDVAVQKVRSLLEAEGRDDLALRIAVQPGGCSGLRYQLYFDDRELDGDVVTDYDGVKVVTDRMSSPYLGGASIDFMDTIEQQGFTIDNPNAQGSCACGDSFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDB6</accession>
    <name>A0A1Q2CDB6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_03790</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03790"/>
    <dbReference type="EnsemblBacteria" id="AQP44045">
        <property type="protein sequence ID" value="AQP44045"/>
        <property type="gene ID" value="RPIT_03790"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03790"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="9"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="152"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="224" mass="24600" checksum="BF9F6AF9F1F56F65" modified="2017-04-12" version="1">MTEEKNRTRVMLVDDHPMWIDALSEDLGEVGFEIVAVAKSGTECLSRARAVRPDVIVMDLQIPAPDGATCTETLLAEFPDIQVLVMSASGERDDVLRAMKAGAKGYLVKSASKAELIEGVRRTAVGDAVFTPGLAGLVLGEFRRMVNAAQARNEEGPVLTTREIEVLRRVAKGMAYKEIADELFVSHRTVQNHVQNVLRKLQLHNRVELTLYAIDQGLHDPGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDF0</accession>
    <name>A0A1Q2CDF0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">ABC-2 type transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_04325</name>
        <name evidence="8" type="ORF">SAMN05428934_101470</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY36149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04325"/>
    <dbReference type="EnsemblBacteria" id="AQP44134">
        <property type="protein sequence ID" value="AQP44134"/>
        <property type="gene ID" value="RPIT_04325"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY36149">
        <property type="protein sequence ID" value="SDY36149"/>
        <property type="gene ID" value="SAMN05428934_101470"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04325"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="6">
        <location>
            <begin position="30"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY36149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="252" mass="26335" checksum="7FC8A54A9DD086A5" modified="2017-04-12" version="1">MSLTFTPDASPAPPMARVWAHARTEASLILRNGEQAILAIVIPMAVLVGSRILGDTLGLTIEEMAPSVLALVMWSSCLTTLAIGTGFERRYNVLERIAATPLGKPGILLGKGLSIAMITAGQVVLLTVAALALGWRPDFSVGSLTVALLVSLLSMGAFAGLALSISGSLRPEATLAVANLLYLIGMPLGVLVPLDRYPTWVQDVLAWLPTGALGETLRGAATGEVLLLPVVVAALWCVGSLALAWKVFTWTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDK2</accession>
    <name>A0A1Q2CDK2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <shortName evidence="5">G6PD</shortName>
            <ecNumber evidence="5">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">zwf</name>
        <name evidence="9" type="ORF">RPIT_04270</name>
        <name evidence="10" type="ORF">SAMN05428934_101458</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY35851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04270"/>
    <dbReference type="EnsemblBacteria" id="AQP44125">
        <property type="protein sequence ID" value="AQP44125"/>
        <property type="gene ID" value="RPIT_04270"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY35851">
        <property type="protein sequence ID" value="SDY35851"/>
        <property type="gene ID" value="SAMN05428934_101458"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04270"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="PTHR23429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 5" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="2 5" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G6PD_N" evidence="7">
        <location>
            <begin position="30"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="G6PD_C" evidence="8">
        <location>
            <begin position="215"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY35851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="513" mass="58058" checksum="6274F6253183796A" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDN9</accession>
    <name>A0A1Q2CDN9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Uridylate kinase</fullName>
            <shortName evidence="6">UK</shortName>
            <ecNumber evidence="6">2.7.4.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Uridine monophosphate kinase</fullName>
            <shortName evidence="6">UMP kinase</shortName>
            <shortName evidence="6">UMPK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pyrH</name>
        <name evidence="8" type="ORF">RPIT_04505</name>
        <name evidence="9" type="ORF">SAMN05428934_101507</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible phosphorylation of UMP to UDP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + UMP = ADP + UDP</text>
            <dbReference type="Rhea" id="RHEA:24400"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.22"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="6">Inhibited by UTP.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the UMP kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.22" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04505"/>
    <dbReference type="EnsemblBacteria" id="AQP44165">
        <property type="protein sequence ID" value="AQP44165"/>
        <property type="gene ID" value="RPIT_04505"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37075">
        <property type="protein sequence ID" value="SDY37075"/>
        <property type="gene ID" value="SAMN05428934_101507"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04505"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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</entry>
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</entry>
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    <accession>A0A1Q2CDQ5</accession>
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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            </authorList>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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        <property type="protein sequence ID" value="SDY38909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="AQP44227"/>
        <property type="gene ID" value="RPIT_04870"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY38909">
        <property type="protein sequence ID" value="SDY38909"/>
        <property type="gene ID" value="SAMN05428934_101582"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Helicase-assoc_dom"/>
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        <property type="entry name" value="Helicase_ATP-bd"/>
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        <property type="entry name" value="Helicase_C"/>
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        <property type="entry name" value="P-loop_NTPase"/>
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    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="24"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="213"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="805"/>
            <end position="827"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY38909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="827" mass="87476" checksum="D709ADA125CE1A3C" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDU7</accession>
    <name>A0A1Q2CDU7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">4HBT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_05230</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05230"/>
    <dbReference type="EnsemblBacteria" id="AQP44289">
        <property type="protein sequence ID" value="AQP44289"/>
        <property type="gene ID" value="RPIT_05230"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05230"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025540">
        <property type="entry name" value="FlK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36934">
        <property type="entry name" value="PTHR36934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF014972">
        <property type="entry name" value="FlK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="3">
        <location>
            <begin position="42"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="42"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR014972-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR014972-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="141" mass="15200" checksum="0DB8CEE3BCC3BAFD" modified="2017-04-12" version="1">MKDSMRPGITGTLSVTVDESLTVPEVSSKYPRFAEMPQVFATGYMVAFAECTAMEAMAPHLDEGEDSVGIGVDMTHTAPTPVGLTVTAVAELVEVDGRILTFTVTLSDDAGPIGEGRHTRAVINREKFDAGVQRRRESIER</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDW4</accession>
    <name>A0A1Q2CDW4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_05190</name>
        <name evidence="2" type="ORF">SAMN05428934_101644</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY40543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05190"/>
    <dbReference type="EnsemblBacteria" id="AQP44281">
        <property type="protein sequence ID" value="AQP44281"/>
        <property type="gene ID" value="RPIT_05190"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY40543">
        <property type="protein sequence ID" value="SDY40543"/>
        <property type="gene ID" value="SAMN05428934_101644"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05190"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021491">
        <property type="entry name" value="DUF3145"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11343">
        <property type="entry name" value="DUF3145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY40543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="174" mass="18609" checksum="D48AEE85F783C49A" modified="2017-04-12" version="1">MSARLDTNSNSQARGMIFVHSAPAALCPHIEWAIGAALNGRPTLTWTAQPAESGSQRAELSWASPIGTGAAIASSLQKLGRVRFEVTEEPSAGSDGQRYCFTPSLGAFSAVVGVHGDILVPEDRLKHAVATDALGGEPIYKGLERLLGVPWDEELDVFRHASEDAPVRWLHQVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDX1</accession>
    <name>A0A1Q2CDX1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_05410</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05410"/>
    <dbReference type="EnsemblBacteria" id="AQP44319">
        <property type="protein sequence ID" value="AQP44319"/>
        <property type="gene ID" value="RPIT_05410"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05410"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="10">
        <location>
            <begin position="10"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="41"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="231"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="392"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="10"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="413"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="479" mass="52258" checksum="78C8501AD5C9191B" modified="2017-04-12" version="1">MSDNEIAVDETFADLGIHESITSALAEVGIVHPFAIQTLAIPLALSGTDLIGQARTGTGKTLAFGVSLLHRMVTLSDGVKPAHGKPRALIVCPTRELALQVGRDLDVAGKHLKMRVLTIYGGTGYDEQLDALDKGIDIAVGTPGRLLDLADRGALSLAEIQVLVLDEADEMLDLGFLPDIERLLRKTPQDRQTMLFSATMPGPIMALARATLNKPVNIRAEGHDAKMTVPDIEQFIYQAHDLDKPELVSRILQGRQTTKVMIFCRTKRSAQRLTDDLVDRGFAAAAIHGDLNQQARERALKKFRADTIKVLVATDVAARGIDITGVSHVINYECPDNDAAYVHRIGRTGRAGNSGIAVTLVDWADVNRWKLIDQALGLDIPDPVETYSSSAHLFEDHDIPEGTKGRLPGAPAAREKAVDKRRAPDEEGRRRRSRRSTEAAGDHPAEKSVGSADGERKPRRRRRRTRGGVDVQPETTPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDX4</accession>
    <name>A0A1Q2CDX4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD+ diphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05440</name>
        <name evidence="4" type="ORF">SAMN05428934_10335</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY66003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05440"/>
    <dbReference type="EnsemblBacteria" id="AQP44324">
        <property type="protein sequence ID" value="AQP44324"/>
        <property type="gene ID" value="RPIT_05440"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY66003">
        <property type="protein sequence ID" value="SDY66003"/>
        <property type="gene ID" value="SAMN05428934_10335"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05440"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="140"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY66003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="282" mass="31269" checksum="FDD50D933A766DAA" modified="2017-04-12" version="1">MIDWREPSQLDRSPALRAEQDLDAAWRAGRVVEVDESGNISAGPEGVRFLDDPGQRQLDDIFVGTFRGEPWFARPVLRMDGESLAWRDIEPGQADPTATAVALSRWHLQSPPCERCGEATRPDLAGARRTCVGCGHWAFPRTDPCVIVAIRDPDDRLLLARQPSWAPKRFSIIAGFIEAGESAEQACHREVYEEVGVELTHLTYVSSQPWPMPRSLMLGFEARSGSASLRPDGLEIAEARFLSRTELARVVGEGSLVLPPPASIARSLIERWRVLPEVDVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDX8</accession>
    <name>A0A1Q2CDX8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosome hibernation promoting factor</fullName>
            <shortName evidence="2">HPF</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hpf</name>
        <name evidence="5" type="ORF">RPIT_05350</name>
        <name evidence="6" type="ORF">SAMN05428934_10317</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with 100S ribosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY65467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05350"/>
    <dbReference type="EnsemblBacteria" id="AQP44308">
        <property type="protein sequence ID" value="AQP44308"/>
        <property type="gene ID" value="RPIT_05350"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY65467">
        <property type="protein sequence ID" value="SDY65467"/>
        <property type="gene ID" value="SAMN05428934_10317"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05350"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00552">
        <property type="entry name" value="RaiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00839">
        <property type="entry name" value="HPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034694">
        <property type="entry name" value="HPF_long/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036567">
        <property type="entry name" value="RHF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003489">
        <property type="entry name" value="RHF/RaiA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032528">
        <property type="entry name" value="Ribosom_S30AE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038416">
        <property type="entry name" value="Ribosom_S30AE_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16321">
        <property type="entry name" value="Ribosom_S30AE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02482">
        <property type="entry name" value="Ribosomal_S30AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69754">
        <property type="entry name" value="SSF69754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00741">
        <property type="entry name" value="yfiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="1 2" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="Ribosom_S30AE_C" evidence="4">
        <location>
            <begin position="142"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY65467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="201" mass="22216" checksum="D8BD54C14E1A98DE" modified="2017-04-12" version="1">MDIVVTGRHCSISPELKELVTDRLASVERLRDRVIRVEVEFHASEGTKDPSDSVEVQLTLRSKGPVVRAEATANDKVAAFEQAYDRLKTQLRKAADRRKTHRGLRAGAIPEFQPPAESTPEADDSGVETQNVAGLVVTGDGPLVVREKEFDSSPLTLAQALDEMELVGHDFFLYQDAESGKPSVVYRRKAYNYGVIHLNVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE13</accession>
    <name>A0A1Q2CE13_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_05505</name>
        <name evidence="2" type="ORF">SAMN05428934_10348</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY66385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05505"/>
    <dbReference type="EnsemblBacteria" id="AQP44337">
        <property type="protein sequence ID" value="AQP44337"/>
        <property type="gene ID" value="RPIT_05505"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY66385">
        <property type="protein sequence ID" value="SDY66385"/>
        <property type="gene ID" value="SAMN05428934_10348"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05505"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046040">
        <property type="entry name" value="DUF5998"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19461">
        <property type="entry name" value="DUF5998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY66385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="187" mass="20173" checksum="B3E71370FCA608E3" modified="2017-04-12" version="1">MPELQDVEANLPPTLVAEIAECGFYPSLVAESVAMGLAGREPLDFLVQHEATFAGHELHRHMTVLVRTAAQLIIVHIDEGEGARDEALATVETVALRSIDSVVVTRAMREPERRAGLNEAWLTIVWGAARRVDLGPAACEDPNCEADHGYTGVIQPDDITVRMSPQADGDNARRLVAFGSRLQGAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE38</accession>
    <name>A0A1Q2CE38_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcriptional regulator, TraR/DksA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_05815</name>
        <name evidence="7" type="ORF">SAMN05428934_103110</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05815"/>
    <dbReference type="EnsemblBacteria" id="AQP44389">
        <property type="protein sequence ID" value="AQP44389"/>
        <property type="gene ID" value="RPIT_05815"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67964">
        <property type="protein sequence ID" value="SDY67964"/>
        <property type="gene ID" value="SAMN05428934_103110"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05815"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000962">
        <property type="entry name" value="Znf_DskA_TraR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01258">
        <property type="entry name" value="zf-dskA_traR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51128">
        <property type="entry name" value="ZF_DKSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DksA C4-type" evidence="5">
        <location>
            <begin position="41"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="dksA C4-type" evidence="4">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY67964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="110" mass="11792" checksum="0A4D91AC8DA958C5" modified="2017-04-12" version="1">MDADDEEILARLDEKSAELRARLGELTAPVDADSVIGFGKRIGDGTTQAIQQMGDASMAQNASHLLDQVEKARAKVAAGTWGTCDVCGEPIGEGRLEARPWSLTCIRHAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE80</accession>
    <name>A0A1Q2CE80_9ACTN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44429">
        <property type="protein sequence ID" value="AQP44429"/>
        <property type="gene ID" value="RPIT_06055"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06055"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="81" mass="8783" checksum="360C24DF2910DA0C" modified="2017-04-12" version="1">MFPLGSCAIGSPTPTTYSEPSSVIWARPRTWKGVSCTWTGWASAVVDEVVDAPDSDRHTVLRFDGHRRRVVEVPTLASAGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE92</accession>
    <name>A0A1Q2CE92_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UPF0716 protein FxsA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05980</name>
        <name evidence="3" type="ORF">SAMN05428934_103142</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05980"/>
    <dbReference type="EnsemblBacteria" id="AQP44417">
        <property type="protein sequence ID" value="AQP44417"/>
        <property type="gene ID" value="RPIT_05980"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68775">
        <property type="protein sequence ID" value="SDY68775"/>
        <property type="gene ID" value="SAMN05428934_103142"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05980"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007313">
        <property type="entry name" value="FxsA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35335">
        <property type="entry name" value="PTHR35335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04186">
        <property type="entry name" value="FxsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY68775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="164" mass="17494" checksum="6A5A6E23B42DF54B" modified="2017-04-12" version="1">MSGRARFGLLGLGVLLLMVAEIAAIVWVSSEIGWWTVLILILTTLLGFYLLQREWRKAWGALADAARSGTMPAGKLTDASLILVGGILLVLPGLLTDVVGVVLLLPFTRPFARSAITWMFSKLVNPVAVAPTVIRGQATDDDTLVPGIDAEPTVIEGTVVDDDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEF5</accession>
    <name>A0A1Q2CEF5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 9">GTPase Der</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GTP-binding protein EngA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">der</name>
        <name evidence="11" type="ORF">RPIT_06090</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">GTPase that plays an essential role in the late steps of ribosome biogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8 9">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06090"/>
    <dbReference type="EnsemblBacteria" id="AQP44435">
        <property type="protein sequence ID" value="AQP44435"/>
        <property type="gene ID" value="RPIT_06090"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06090"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00195">
        <property type="entry name" value="GTPase_Der"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031166">
        <property type="entry name" value="G_ENGA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016484">
        <property type="entry name" value="GTP-bd_EngA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032859">
        <property type="entry name" value="KH_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14714">
        <property type="entry name" value="KH_dom-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006485">
        <property type="entry name" value="GTP-binding_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03594">
        <property type="entry name" value="GTPase_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51712">
        <property type="entry name" value="G_ENGA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 7 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="EngA-type G" evidence="10">
        <location>
            <begin position="19"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="EngA-type G" evidence="10">
        <location>
            <begin position="193"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="25"/>
            <end position="32"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="72"/>
            <end position="76"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="134"/>
            <end position="137"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="199"/>
            <end position="206"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="246"/>
            <end position="250"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="311"/>
            <end position="314"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="454" mass="49684" checksum="A000BF536815C8CF" modified="2017-04-12" version="1">MGWGIPQSEGAPVTELAKPIVAVVGRPNVGKSTLVNRILGRREAVVQDQPGVTRDRVSYDANWNGREFVLVDTGGWMSDAKGMAAAIAEQAELAISMADAVLFVVDATVGTTDEDEAVVRVLRRSKKPVVLAANKVDDQRHEALAATMWNLGLGEPYPVSAMHGRGSGDLLDALLDSIPEAPREQDVEEAGPRRVAIVGKPNVGKSSLLNKLADQQRVVVSDVSGTTVDPVDEIVEVGGQVYRLIDTAGIRRRVKEASGHEYYASLRTQAAIERAEVCIMVVDASEPLTDQDLRILSSIEEAGRALVIAFNKWDLTDEERRRYLEREIERDLVAFRWAPTVNISALTGRNVDKLSKAIEAAAAGWETRISTGKLNAFLGRLAAAHPHPVRGGKQPRILFGTQAQTSPPTFALFTSGQMDATYLRFIERRLREDFGFVGSPVHVEIRAREKRKDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEK1</accession>
    <name>A0A1Q2CEK1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP synthase epsilon chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">ATP synthase F1 sector epsilon subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">F-ATPase epsilon subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">atpC</name>
        <name evidence="10" type="ORF">RPIT_06660</name>
        <name evidence="11" type="ORF">SAMN05428934_110115</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7 8">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cell membrane</location>
            <topology evidence="1 7">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the ATPase epsilon chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ10308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06660"/>
    <dbReference type="EnsemblBacteria" id="AQP44533">
        <property type="protein sequence ID" value="AQP44533"/>
        <property type="gene ID" value="RPIT_06660"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ10308">
        <property type="protein sequence ID" value="SDZ10308"/>
        <property type="gene ID" value="SAMN05428934_110115"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06660"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12152">
        <property type="entry name" value="F1-ATPase_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00530">
        <property type="entry name" value="ATP_synth_epsil_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001469">
        <property type="entry name" value="ATP_synth_F1_dsu/esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020546">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036771">
        <property type="entry name" value="ATPsynth_dsu/esu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822">
        <property type="entry name" value="PTHR13822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02823">
        <property type="entry name" value="ATP-synt_DE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51344">
        <property type="entry name" value="SSF51344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01216">
        <property type="entry name" value="ATP_synt_epsi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7 8" id="KW-0139">CF(1)</keyword>
    <keyword evidence="7" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 7 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_DE_N" evidence="9">
        <location>
            <begin position="6"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDZ10308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="135" mass="14354" checksum="551B222D00E19EDE" modified="2017-04-12" version="1">MERPPLEVEVVSAERVVWSGEAVNVVARTVEGDIGILPGHEPLLAVLVPCLVEIVTADGRSESLAVDGGFISVANGHVSVLSQTAELGKEISLEDARKELAPIELKAQQGQADDAEIHRLKMLKAQIRAGERATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEN3</accession>
    <name>A0A1Q2CEN3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">D-3-phosphoglycerate dehydrogenase</fullName>
            <ecNumber evidence="6">1.1.1.399</ecNumber>
            <ecNumber evidence="7">1.1.1.95</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">2-oxoglutarate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">RPIT_06830</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:12641"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="EC" id="1.1.1.95"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:49612"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.399"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 11">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.399" evidence="6"/>
    <dbReference type="EC" id="1.1.1.95" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06830"/>
    <dbReference type="EnsemblBacteria" id="AQP44561">
        <property type="protein sequence ID" value="AQP44561"/>
        <property type="gene ID" value="RPIT_06830"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06830"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00196"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004617">
        <property type="term" value="F:phosphoglycerate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0718">Serine biosynthesis</keyword>
    <feature type="domain" description="ACT" evidence="12">
        <location>
            <begin position="328"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00021582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP44561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="396" mass="42336" checksum="5A4882DC2B95F8B7" modified="2017-04-12" version="1">MKALLLENIHADAVKALEARGYEVETRAGALADQELIAALDGVDYLGIRSRTHVTREVLAAAPQLRAVGAFCIGTNQIDLEAATEAGVAVFNAPYSNTRSVVELAIAEIITMARRLADKNRDMHAGVWDKSAQGAHEVRGRTLGIVGYGNIGSQLSVMAEALGMRVLFYDVVDKLALGNARRVDSLDELLAEAETISLHVDGRASNTNLFGPAEFAKMRPRSLFLNLCRGSVVDIDALHDALVSGHVAGAAIDVFPSEPKAKDEPFVSKLQGLPNVILTPHVGGSTLEAQVDIGRFVAGKLADYESWGSTSMSVNLPEVTAGPLQEARIVHLHHNVPGVLARLNSALANHNMNIGSQTLATKGHYGYAVTDISGERYDGLLAELEALDETIRVRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEQ1</accession>
    <name>A0A1Q2CEQ1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 17">Homoserine dehydrogenase</fullName>
            <ecNumber evidence="6 17">1.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">RPIT_06745</name>
        <name evidence="21" type="ORF">SAMN05428934_11098</name>
    </gene>
    <organism evidence="20 22">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="20 22" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 22">RP1T</strain>
        </source>
    </reference>
    <reference evidence="21 23" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 23">RP1</strain>
        </source>
    </reference>
    <reference evidence="20" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-homoserine + NAD(+) = H(+) + L-aspartate 4-semialdehyde + NADH</text>
            <dbReference type="Rhea" id="RHEA:15757"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>L-homoserine + NADP(+) = H(+) + L-aspartate 4-semialdehyde + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15761"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 17">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 3/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 17">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 18">Belongs to the homoserine dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.3" evidence="6 17"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06745"/>
    <dbReference type="EnsemblBacteria" id="AQP44550">
        <property type="protein sequence ID" value="AQP44550"/>
        <property type="gene ID" value="RPIT_06745"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09985">
        <property type="protein sequence ID" value="SDZ09985"/>
        <property type="gene ID" value="SAMN05428934_11098"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06745"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00063"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004412">
        <property type="term" value="F:homoserine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005106">
        <property type="entry name" value="Asp/hSer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016204">
        <property type="entry name" value="HDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001342">
        <property type="entry name" value="HDH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019811">
        <property type="entry name" value="HDH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00742">
        <property type="entry name" value="Homoserine_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03447">
        <property type="entry name" value="NAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000098">
        <property type="entry name" value="Homoser_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01042">
        <property type="entry name" value="HOMOSER_DHGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 17" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="14 17" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="9 17" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="13 17" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="11 16 17" id="KW-0521">NADP</keyword>
    <keyword evidence="12 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 17" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="ACT" evidence="19">
        <location>
            <begin position="350"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="15">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="10"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000098-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000098-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU004171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="AQP44550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="SDZ09985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="434" mass="45453" checksum="D9040A8096ACE9C0" modified="2017-04-12" version="1">MSKPLKVALLGAGVVGSQVARIILKEGGTLESRIGRRLELVGIGVRNAATQRPGIDPALITTDLEGLVSRGDLDIVIELIGGIEPALGLLRTAIANGASVVSANKALLADYLGELSRDADARGVDLYYEAAVAGAIPIIRPLRESLVGDDITAVMGIVNGTTNYILDKMVTEQVSYDSALAEAQQLGYAEADPTADVEGHDAAAKAAILAGLAFHTEVKREEVFCEGITSVTPDDIAAAELMGCTVKLLAIAKLTDDDRVIVKVHPAMVANKHPLASVSGAYNAIFVNSREAGELMFLGQGAGGAPTASAVMGDVVTVARNRHRGTAGHLGSAYTARQVAPIGESQAQFYVSFEVVDRPGVLARCAAVFGDHGVSLRVVQQSYIEGGERREGFAARLGVMTHVTQETNLSAVVEELGRADFVGSEIRVMRVEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CES0</accession>
    <name>A0A1Q2CES0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07175</name>
        <name evidence="2" type="ORF">SAMN05428934_1109</name>
    </gene>
    <organism evidence="1 3">
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
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    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07175"/>
    <dbReference type="EnsemblBacteria" id="AQP44622">
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        <property type="gene ID" value="RPIT_07175"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08153">
        <property type="protein sequence ID" value="SDZ08153"/>
        <property type="gene ID" value="SAMN05428934_1109"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07175"/>
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    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ08153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="328" mass="34226" checksum="06CFF802C56B3594" modified="2017-04-12" version="1">MRVHPRPTRPNCPAVGHDHPLLDLTGKVAVVTGGASGIGYFTAEGLAALGAHVVIAGRNEERARAARLAIARQVPDAQVSYQPLDLADLASVRAAAETLAGLPALDILVANAGAIGLPNHTRPPAERGIRPRTTADGHELFWGTNFLGHYVLVATLLPLLLASAGRCVVVGSIGDRGAPLPGDALPPVDLKASDLAKYGQSKLATTTLMHELARRLGTGGGAAALGAHPGTAVDFLSPPRDVAVNQPEAAGLLQWPTRLFTHGKHRGAAPVLTAAACPQARNGDYWGPKWLTKGPPTTVRPNPATRDEATARRLLEMASALTRVRIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CET5</accession>
    <name>A0A1Q2CET5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PAC2 family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Proteasome protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07140</name>
        <name evidence="2" type="ORF">SAMN05428934_11016</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07140"/>
    <dbReference type="EnsemblBacteria" id="AQP44616">
        <property type="protein sequence ID" value="AQP44616"/>
        <property type="gene ID" value="RPIT_07140"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08307">
        <property type="protein sequence ID" value="SDZ08307"/>
        <property type="gene ID" value="SAMN05428934_11016"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07140"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ08307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="306" mass="33491" checksum="9EA21C8138CC99C9" modified="2017-04-12" version="1">MQNPSDLYRFVTDPEPAPQGNVLLVALGSFIDAGQVQRLLSGHLLETGDAELIATFDIDQLYDYRGRRPTMTFDSNRWAEYDAPSMLLHRLTDRDGETYHLLTGAEPDFQWERVVEAIRELVETLRVALVVTVHGVPMGVPHTRPVGFTAHSTDPSLIGDAHSPFGRVQVPGSIAALLELRLGQLGHRAAGFAIHVPHYLAASEFAEGALTALNAVVDLTRLSLPNDDLVEKAEINRRAIAAEVEGNEEVVAIVSALEQQYDAFMQGQHLPSLWAEGAKLPSADQLGAELEDFLRTVSDEDPDQDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEU4</accession>
    <name>A0A1Q2CEU4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07210</name>
        <name evidence="3" type="ORF">SAMN05428934_1102</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44626">
        <property type="protein sequence ID" value="AQP44626"/>
        <property type="gene ID" value="RPIT_07210"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08009">
        <property type="protein sequence ID" value="SDZ08009"/>
        <property type="gene ID" value="SAMN05428934_1102"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07210"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ08009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="233" mass="25092" checksum="CF47A6DCC4A02C0D" modified="2017-04-12" version="1">MNVETPDTEPLEFTGVARGDNGPREAVATVLRDADAYAELLEGEPPTDPPIDWATEVVTAVALGARPSGTVVRIEEIRFYHLGIRGGTVDVMYREVPGNGDDDRVTYPYHAVRSSSFGHAFFHPIGVDDVPSALFRDWRGPIRTDNDGVGTYLPREDAPLSRSVAGFSVEEDGAFTAVHDGPADGPVSVPGRWQATADGLSVALDDGRAFRLDLVSVDEQELRARVGEEPSSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEW2</accession>
    <name>A0A1Q2CEW2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_07440</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07440"/>
    <dbReference type="EnsemblBacteria" id="AQP44662">
        <property type="protein sequence ID" value="AQP44662"/>
        <property type="gene ID" value="RPIT_07440"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07440"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018973">
        <property type="entry name" value="MZB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09369">
        <property type="entry name" value="DUF1998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="3">
        <location>
            <begin position="91"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="4">
        <location>
            <begin position="1013"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="365"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1274"/>
            <end position="1315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="2131" mass="230079" checksum="359817DD02C1741C" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEW7</accession>
    <name>A0A1Q2CEW7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_07015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07015"/>
    <dbReference type="EnsemblBacteria" id="AQP44595">
        <property type="protein sequence ID" value="AQP44595"/>
        <property type="gene ID" value="RPIT_07015"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07015"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
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        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="144"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="220" mass="23993" checksum="B87A066048A0E8FE" modified="2017-04-12" version="1">MPSEPVRIALLNDYDVVVHGVRSMLEPYRDRVVVVEMDLQVPVARKVDIALYDTFSQAQVDTADLDGLLADETNGAVAIYTWNMQPDLAEQALRKGCRGYLGKSLSSVELVEALEAIAQGETIVAGTDMGPQEPIPLRPEALKWPGADAGLTPRESEVLALITQGLTNADIASRSYLSINSVKSYIRSAYRKIGVERRSQAVRWGLENGMLPDVGRVVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEY2</accession>
    <name>A0A1Q2CEY2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF262 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07460</name>
        <name evidence="3" type="ORF">SAMN05428934_11913</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000019">
        <property type="protein sequence ID" value="SDZ21984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07460"/>
    <dbReference type="EnsemblBacteria" id="AQP44666">
        <property type="protein sequence ID" value="AQP44666"/>
        <property type="gene ID" value="RPIT_07460"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ21984">
        <property type="protein sequence ID" value="SDZ21984"/>
        <property type="gene ID" value="SAMN05428934_11913"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07460"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="DUF262"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="DUF262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF262" evidence="1">
        <location>
            <begin position="12"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ21984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="701" mass="79659" checksum="2B94EC00075287D2" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFD0</accession>
    <name>A0A1Q2CFD0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sec-independent protein translocase protein TatA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tatA</name>
        <name evidence="9" type="ORF">RPIT_08005</name>
        <name evidence="10" type="ORF">SAMN05428934_11341</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TatA/E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08005"/>
    <dbReference type="EnsemblBacteria" id="AQP44755">
        <property type="protein sequence ID" value="AQP44755"/>
        <property type="gene ID" value="RPIT_08005"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16788">
        <property type="protein sequence ID" value="SDZ16788"/>
        <property type="gene ID" value="SAMN05428934_11341"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08005"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00236">
        <property type="entry name" value="TatA_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006312">
        <property type="entry name" value="TatA/E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01411">
        <property type="entry name" value="tatAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="48"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ16788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="101" mass="11283" checksum="CF5E71219C8E7609" modified="2017-04-12" version="1">MPTLLFAGGWEWVIILVVALLLFGGSRLAGLGKGVGRSIREFKEEVKHPIDGSKPADEVVDAEIVQPEIRQRPVERPVDPEYDRPAERPAQQPHTERHPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFD2</accession>
    <name>A0A1Q2CFD2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_08480</name>
        <name evidence="2" type="ORF">SAMN05428934_1077</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY96285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44824">
        <property type="protein sequence ID" value="AQP44824"/>
        <property type="gene ID" value="RPIT_08480"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY96285">
        <property type="protein sequence ID" value="SDY96285"/>
        <property type="gene ID" value="SAMN05428934_1077"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08480"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY96285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="153" mass="16773" checksum="7A86981A801651EE" modified="2017-04-12" version="1">MPAVVGDTRHHLCATVEVSAGHEGVIMGFLNKLFGKADDNDNAPVAPFDSASVRSEVDELISALGALTDAMDTEDAPLSNPGWRGRLHDLREVRGDLRILTRRQDFTKDDLYEVLTCVRPLYRGEPPKDFAHLAPQNERVVSAIEDVHRAAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFH8</accession>
    <name>A0A1Q2CFH8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Patatin family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Predicted phospholipase, patatin/cPLA2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_08825</name>
        <name evidence="5" type="ORF">SAMN05428934_10775</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08825"/>
    <dbReference type="EnsemblBacteria" id="AQP44882">
        <property type="protein sequence ID" value="AQP44882"/>
        <property type="gene ID" value="RPIT_08825"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97824">
        <property type="protein sequence ID" value="SDY97824"/>
        <property type="gene ID" value="SAMN05428934_10775"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08825"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07208">
        <property type="entry name" value="Pat_hypo_Ecoli_yjju_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037483">
        <property type="entry name" value="YjjU-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="12"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="43"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="170"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY97824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="295" mass="32997" checksum="C68452E16B289880" modified="2017-04-12" version="1">MQITTNVSDTALIFEGGGMRAAFSSGVLAALLEGGVHCDWVGGISAGSSCLVNYVSRDPLRAERAFVDFAAEPEFGSWRTWVRGKGVFNAEWIYEQTSLPHQPLPLDWETFTGNPAQIRVGGFRCADGETVYWGRDEMATIEAVMKRVRASSTMPGLMPITSVDGVDYCDGALGPTGGFAVDAAREDGYERFLVVMTRERGYRKTATRFPHAYQQLFRRYPAIARALLERPANYNRTLDELLELERQGRAYLVFPDSMPISNSERNVDVLRFVFRSGLAQARREMPRIREFLNLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFI5</accession>
    <name>A0A1Q2CFI5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Valine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Valyl-tRNA synthetase</fullName>
            <shortName evidence="7">ValRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">valS</name>
        <name evidence="11" type="ORF">RPIT_08785</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val)</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08785"/>
    <dbReference type="EnsemblBacteria" id="AQP44874">
        <property type="protein sequence ID" value="AQP44874"/>
        <property type="gene ID" value="RPIT_08785"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08785"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02005">
        <property type="entry name" value="Val_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022874">
        <property type="entry name" value="Valine-tRNA_ligase_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="PTHR11946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="9">
        <location>
            <begin position="23"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="10">
        <location>
            <begin position="659"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="7">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="7">
        <location>
            <begin position="581"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="584"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="853" mass="95046" checksum="A7DE7BB7EA56FAC1" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFJ8</accession>
    <name>A0A1Q2CFJ8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pimeloyl-ACP methyl ester carboxylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08750</name>
        <name evidence="3" type="ORF">SAMN05428934_10760</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44867">
        <property type="protein sequence ID" value="AQP44867"/>
        <property type="gene ID" value="RPIT_08750"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97508">
        <property type="protein sequence ID" value="SDY97508"/>
        <property type="gene ID" value="SAMN05428934_10760"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08750"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="17"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY97508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="253" mass="27619" checksum="0DB8A6C7BED2DCE4" modified="2017-04-12" version="1">MSDLHVHRYGNPDAPPLVLVHGLTDDGTCWPDAVERWRDTWQIISIDQRGHGRSPRFTEDQYGDSPAILRDDLSKVLSGLAQPAIVVGHSLGGLVAARSAQSHPELVRALVLEDPAKPSGRNRPSRTFSRGQLEFVEAVTADPEAEVTRMRAETPWSESELAAWAPAKARVDRGYLAHGLYLGDAAWETMFDGLRVPTLIVGPVGGEMLPDASLIANPLVSVIEVPDAGHCVRRDAPAAFHAVVDRFLEQHRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFK3</accession>
    <name>A0A1Q2CFK3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate ABC transporter substrate-binding protein, CUT1 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Sugar ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08865</name>
        <name evidence="3" type="ORF">SAMN05428934_10784</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08865"/>
    <dbReference type="EnsemblBacteria" id="AQP44888">
        <property type="protein sequence ID" value="AQP44888"/>
        <property type="gene ID" value="RPIT_08865"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97973">
        <property type="protein sequence ID" value="SDY97973"/>
        <property type="gene ID" value="SAMN05428934_10784"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08865"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544470" evidence="1">
        <location>
            <begin position="34"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY97973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="428" mass="46342" checksum="A8ADCA5BC107296A" modified="2017-04-12" version="1">MKSRRKGKKQAISALLAAALALALAGCSPDAGDDVVTLSFLQFKGEARQQFDTIIDEFEAANPDIRVVQNQVADADTTIRTLLVKDRAPDVMTLNANGGFGRLATAGVFHDFTGDPVLETTNPAVQEILADLGNKQGEVNSLGYVNNANGIIYNTEIFEQQGLEIPETWEELFTVCEKLQAAGITPFYGTLADSWTVLPSFNAIGAYAAQDGFFDKMRAAGREVGPDSAVSFQKDFDEVLQRQAELFAYAQDGYRGKTYDDGNAAFARGEVAMYMQGIWALAPIQAINPDIEAAIFPYPALSDVPEDRLLVTGVDVTVTIAKDTPHLEEALRFVHFLFEEDVIAEFAASQNMVPSVIGAELSDDPALQSVAPYFDDGRIAGFIDHQVPSSIPLDTTVQQALFTGDVPSALATLDNEWRKVAARTIQGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFK5</accession>
    <name>A0A1Q2CFK5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08935</name>
        <name evidence="3" type="ORF">SAMN05428934_107100</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44899">
        <property type="protein sequence ID" value="AQP44899"/>
        <property type="gene ID" value="RPIT_08935"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98258">
        <property type="protein sequence ID" value="SDY98258"/>
        <property type="gene ID" value="SAMN05428934_107100"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08935"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY98258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="67" mass="7242" checksum="1DF6DD7597B6DF66" modified="2017-04-12" version="1">MNVALLEVLPGWPEAQTLSDVEMILLMVVGPLAFGAVVSLMVFGPKMARRGRGDAATSTEVERVEQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFL9</accession>
    <name>A0A1Q2CFL9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP-dependent DNA helicase RecG</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_08710</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RecG subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08710"/>
    <dbReference type="EnsemblBacteria" id="AQP44860">
        <property type="protein sequence ID" value="AQP44860"/>
        <property type="gene ID" value="RPIT_08710"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08710"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045562">
        <property type="entry name" value="RecG_dom3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033454">
        <property type="entry name" value="RecG_wedge"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19833">
        <property type="entry name" value="RecG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17191">
        <property type="entry name" value="RecG_wedge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="311"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="507"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="749" mass="80412" checksum="7780ABEDD90D8A6B" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFP8</accession>
    <name>A0A1Q2CFP8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09155"/>
    <dbReference type="EnsemblBacteria" id="AQP44934">
        <property type="protein sequence ID" value="AQP44934"/>
        <property type="gene ID" value="RPIT_09155"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09155"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="76" mass="8516" checksum="DE80767A4A6DAFBD" modified="2017-04-12" version="1">MEATMPTFFDSTVDAAEASEALRGLAHASRAFDQHAQMYGVIGDLSSGMRSLPPRQRKWARLTPRPRVDPWSRVQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFV1</accession>
    <name>A0A1Q2CFV1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase sigma-70 factor, sigma-E family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_09425</name>
        <name evidence="8" type="ORF">SAMN05428934_102422</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY60329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44977">
        <property type="protein sequence ID" value="AQP44977"/>
        <property type="gene ID" value="RPIT_09425"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY60329">
        <property type="protein sequence ID" value="SDY60329"/>
        <property type="gene ID" value="SAMN05428934_102422"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09425"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="12"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="101"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY60329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="165" mass="18864" checksum="2DFF3B889E5A3083" modified="2017-04-12" version="1">MFEQVAAGFDAFVRRTRDDLWRAAWLLTGDHHRADDLVQTALGRTYGRYESIGNDHKFEAYVRTTMYRTYASWWRRKWNGEVPDQGADERSANPVADVNLDLIRALNALPRMQRAVLVLRFFEDRSVAEVANLLGIAEGTVKAHTSQGCAALRRSPHLADDKEWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG06</accession>
    <name>A0A1Q2CG06_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09835</name>
        <name evidence="3" type="ORF">SAMN05428934_102339</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY58043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09835"/>
    <dbReference type="EnsemblBacteria" id="AQP45049">
        <property type="protein sequence ID" value="AQP45049"/>
        <property type="gene ID" value="RPIT_09835"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY58043">
        <property type="protein sequence ID" value="SDY58043"/>
        <property type="gene ID" value="SAMN05428934_102339"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09835"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021385">
        <property type="entry name" value="DUF3017"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11222">
        <property type="entry name" value="DUF3017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY58043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="94" mass="9879" checksum="63880137640E2665" modified="2017-04-12" version="1">MPDKPADSYPDNPWPLLLVLAAVLVGVGYAGFGHWRRAALMIAGALALGAGLRAVLPPRLAGLLVVRRRWIDVAVMATFGVAIAVVSLVVPPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG13</accession>
    <name>A0A1Q2CG13_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Nucleoside ABC transporter membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_09770</name>
        <name evidence="8" type="ORF">SAMN05428934_102351</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY58405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09770"/>
    <dbReference type="EnsemblBacteria" id="AQP45037">
        <property type="protein sequence ID" value="AQP45037"/>
        <property type="gene ID" value="RPIT_09770"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY58405">
        <property type="protein sequence ID" value="SDY58405"/>
        <property type="gene ID" value="SAMN05428934_102351"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09770"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY58405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="430" mass="45171" checksum="3386386619198030" modified="2017-04-12" version="1">MSTAIIPPSVERARMESPEGRKQRRSIGILLTLLGAVLAFLAFTTNDTGRIALSDVFADVKLPTLEVPGLPTVLLCALLVLGAGIGYLTGKVSGRARTIAATVAGIGILVGFIVWAAASSTLPFTLTSQLNLTLEYATPLLFGVLAGVLSERAGVVNIAIEGQFLTAAFAASLTYSITRSFIAALFAAALAGLLMGGVLALFTLRYLVDHVIIGVVVNLLATGLTGFIYQQLVVQDLASYGNVQPMSPLRIPLLESIPFLGPILFTQKPLTYGGILSVALVWFLIYRTKWGLRVRSVGEHPHAADTVGINVISTKTQAVLLGGLFAGLGGAYFTIGSVGAFQDNNPTAGNGFIALAAVIMGRWHPVLAAMMALFFGFARALAQSTKPMQLPIPSDFIEMLPYLATIIAVAGLVGRVRAPAADGAHFVKTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG23</accession>
    <name>A0A1Q2CG23_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Cysteine synthase</fullName>
            <ecNumber evidence="4 10">2.5.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_09930</name>
        <name evidence="13" type="ORF">SAMN05428934_102320</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>hydrogen sulfide + O-acetyl-L-serine = acetate + L-cysteine</text>
            <dbReference type="Rhea" id="RHEA:14829"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.5.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="4 10"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY57443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09930"/>
    <dbReference type="EnsemblBacteria" id="AQP45068">
        <property type="protein sequence ID" value="AQP45068"/>
        <property type="gene ID" value="RPIT_09930"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57443">
        <property type="protein sequence ID" value="SDY57443"/>
        <property type="gene ID" value="SAMN05428934_102320"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09930"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005856">
        <property type="entry name" value="Cys_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005859">
        <property type="entry name" value="CysK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01139">
        <property type="entry name" value="cysK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01136">
        <property type="entry name" value="cysKM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="6 8 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PALP" evidence="11">
        <location>
            <begin position="8"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="8">
        <location>
            <begin position="176"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP45068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY57443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="309" mass="32116" checksum="69EB3CF3AFCA276B" modified="2017-04-12" version="1">MNIFPDITATVGRTPLVKLNRIAGDNATVLAKLESFNPAASVKDRIGVAIIDAAVASGELQPGGTIVEGTSGNTGIALAMVGAARGYKVVLTMPETMSVERRALLRAYGAELVLTPGPAGMRGAVEKAEEIAAERGGILARQFANQANVDIHRSTTAEEIWQDTDGTVDIFVAGIGTGGTISGVGQVLKERKPEVQIVAVEPQESAILSGNAPGPHKIQGIGANFIPEILDRGVIDEVLPRNIDQSVDFARRSATEEGVLVGLSSGAALSAAIEVANRPENAGKTIVVLLASFGERYLSTVLFEGLADQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG52</accession>
    <name>A0A1Q2CG52_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-dependent synthetase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Acetyl-CoA synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09695</name>
        <name evidence="4" type="ORF">SAMN05428934_102366</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY58848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09695"/>
    <dbReference type="EnsemblBacteria" id="AQP45025">
        <property type="protein sequence ID" value="AQP45025"/>
        <property type="gene ID" value="RPIT_09695"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY58848">
        <property type="protein sequence ID" value="SDY58848"/>
        <property type="gene ID" value="SAMN05428934_102366"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09695"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="60"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="450"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY58848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="559" mass="62014" checksum="40A0EE19934CC136" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGB7</accession>
    <name>A0A1Q2CGB7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10415"/>
    <dbReference type="EnsemblBacteria" id="AQP45156">
        <property type="protein sequence ID" value="AQP45156"/>
        <property type="gene ID" value="RPIT_10415"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10415"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="173" mass="18628" checksum="D03270CA3BF8C6F9" modified="2017-04-12" version="1">MTGHLIVISGLPGVGKTSVAEVVAARTGSMHLSIDAVEESILACGLPRGWQVGVAAYEAVGTMADLNLRLGQTVIIDAVNDSEEARQTWRGAATRNESRIEFVHLVISDALEHERRLASRDRGLAHVGEPTWADVRRRRAGYAAWSDAAVEIDTAVQTVDEIADAIISRLDFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGF5</accession>
    <name>A0A1Q2CGF5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Rhodanese-related sulfurtransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10330</name>
        <name evidence="3" type="ORF">SAMN05428934_102239</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45140">
        <property type="protein sequence ID" value="AQP45140"/>
        <property type="gene ID" value="RPIT_10330"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55296">
        <property type="protein sequence ID" value="SDY55296"/>
        <property type="gene ID" value="SAMN05428934_102239"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10330"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="38"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY55296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="138" mass="15008" checksum="7E53C2306D226132" modified="2017-04-12" version="1">MASREPGTPLRRSFADLVGEANAIVPPLPLADAARLLGDDTVLFVDLREPGEIAREGQIPGAYRAPRGLLEFWVDPASPYYRADLDSGRRLVLYCASAWRSALAARSLVEMGMTDVTHIDGGFSAWKNAGHPIESSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGP2</accession>
    <name>A0A1Q2CGP2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_11105</name>
        <name evidence="7" type="ORF">SAMN05428934_10283</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY50509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11105"/>
    <dbReference type="EnsemblBacteria" id="AQP45274">
        <property type="protein sequence ID" value="AQP45274"/>
        <property type="gene ID" value="RPIT_11105"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY50509">
        <property type="protein sequence ID" value="SDY50509"/>
        <property type="gene ID" value="SAMN05428934_10283"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11105"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="4">
        <location>
            <begin position="30"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY50509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="118" mass="13188" checksum="60E24158C66CFE7D" modified="2017-04-12" version="1">MATTDLTAENFETIVKDNEVVLIDFWADWCAPCKRFSPIFEEASGRHDDVVFGKVDTEDARDLAAALEIQSIPTIMGFRKGNLVFRQAGLLSGKQLDSLIEQIKELDIDALVEEAKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGQ5</accession>
    <name>A0A1Q2CGQ5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11225</name>
        <name evidence="3" type="ORF">SAMN05428934_10259</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY49828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11225"/>
    <dbReference type="EnsemblBacteria" id="AQP45296">
        <property type="protein sequence ID" value="AQP45296"/>
        <property type="gene ID" value="RPIT_11225"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY49828">
        <property type="protein sequence ID" value="SDY49828"/>
        <property type="gene ID" value="SAMN05428934_10259"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11225"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="53"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY49828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="202" mass="21558" checksum="FC5894AAE69B1BA0" modified="2017-04-12" version="1">MAPEPSKWTRIIAADPSHSARYIQRFKTMEAEGHDLGGEARTVDAMVPRGSRILDAGCGPGRVGGRLHAMGHTVVGVDVDSALIAAAEQDYPGPTWITGDLAELDLPSHGISEPFDVIVAAGNVMGFLAPSTRVDVLRRFADHLAPEGRAIIGFGGGRGYEFSDFFADLDEAGLALDLPLETWDLRPFTAASTFLVAICRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGT4</accession>
    <name>A0A1Q2CGT4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2,3-bisphosphoglycerate-dependent phosphoglycerate mutase</fullName>
            <ecNumber evidence="4">5.4.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_11325</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.11" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11325"/>
    <dbReference type="EnsemblBacteria" id="AQP45313">
        <property type="protein sequence ID" value="AQP45313"/>
        <property type="gene ID" value="RPIT_11325"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11325"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004619">
        <property type="term" value="F:phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005952">
        <property type="entry name" value="Phosphogly_mut1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11931">
        <property type="entry name" value="PTHR11931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01258">
        <property type="entry name" value="pgm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="245" mass="26725" checksum="EFACD6942612A362" modified="2017-04-12" version="1">MGTLMLLRHGESTYNAQQVFTGLLDAGLTPAGEAQVAVAADLIRGADLRPDVVWQSTMLRSLRTTELLLSHLGLEDFDPRSTWRLVERAYGVLTDLPKREARHRYGDHAFHEWRRTINGRPPHATAEQVASWTDPAPVAERGSLPAGVGESLADVIERVRPWWDEDVHPDLVAGRTVFVVAHGNTLRALADVVLGLSDREVEDLNIPAGHPLTLEFSDGRPGSPRYLDPDVAQRAAAAVAAEGGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGU3</accession>
    <name>A0A1Q2CGU3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45265">
        <property type="protein sequence ID" value="AQP45265"/>
        <property type="gene ID" value="RPIT_11050"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11050"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="115" mass="12722" checksum="F1F8A1DB2950D372" modified="2017-04-12" version="1">MSDDAALAEALGQALTGERLQLTSPALLEGQLAELGYDRRRLGEIRARCQEVRAAWPFDVGPDTRRAIGFARFDAALAEARSALGLDGLRPTMPTVRPLDRDDRRLTEDRPPHWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGV6</accession>
    <name>A0A1Q2CGV6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="3 13">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">RPIT_11435</name>
        <name evidence="17" type="ORF">SAMN05428934_10217</name>
    </gene>
    <organism evidence="16 18">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 18" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1T</strain>
        </source>
    </reference>
    <reference evidence="17 19" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">RP1</strain>
        </source>
    </reference>
    <reference evidence="16" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NAD(+) = (R)-N(6)-lipoyl-L-lysyl-[protein] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11 13">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="13">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="3 13"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY48475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11435"/>
    <dbReference type="EnsemblBacteria" id="AQP45333">
        <property type="protein sequence ID" value="AQP45333"/>
        <property type="gene ID" value="RPIT_11435"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY48475">
        <property type="protein sequence ID" value="SDY48475"/>
        <property type="gene ID" value="SAMN05428934_10217"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11435"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11 13" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 13" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="15">
        <location>
            <begin position="6"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="14">
        <location>
            <begin position="341"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="441"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="139"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="177"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="43"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="AQP45333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="SDY48475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="457" mass="47687" checksum="1005161ED03326AE" modified="2017-04-12" version="1">MSETNFDVIVLGGGPGGYIAAERLGHAKKKVLLIEAEALGGTCLNVGCIPTKALLGAAKTYDHARHAGAQGVHAPDITVDWAEMQAWKAKTVSTLVGGVGAAEKKAGVTVVKGHGRFDGPGRVTVGEETYSARHVILATGSVPVMPPIPGAADNPAVVDSTGLLAIEEIPARLAVIGGGVIGLEFASLFAMLGSEVTVIEMLPEIVPFMDDDLAAQLRKGLADVSFQLESRVTAIDGGVVRYSAKDGSEQSVEAEVVLMAVGRRPAVQGWGAENTGLEHSGKGVVVDERMRTNLPNVWAVGDVTGRSLLAHAAYRMGEIAAANILDPDAHLRGERMRWNTIPWAVYSNPEAAGIGATESQARAEGRAVGTVTVPGYLSGRFVAEAGVKAPGACKLVYDSTTGQVLGVNVLGTYASETIWGASVVLETELSIHDLRQVVYPHPTVSELIREAAWAAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGW5</accession>
    <name>A0A1Q2CGW5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rhamnulokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_11485</name>
        <name evidence="5" type="ORF">SAMN05428934_1026</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY48123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11485"/>
    <dbReference type="EnsemblBacteria" id="AQP45343">
        <property type="protein sequence ID" value="AQP45343"/>
        <property type="gene ID" value="RPIT_11485"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY48123">
        <property type="protein sequence ID" value="SDY48123"/>
        <property type="gene ID" value="SAMN05428934_1026"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11485"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008993">
        <property type="term" value="F:rhamnulokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019301">
        <property type="term" value="P:rhamnose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07771">
        <property type="entry name" value="FGGY_RhuK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013449">
        <property type="entry name" value="Rhamnulokinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0684">Rhamnose metabolism</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="2">
        <location>
            <begin position="6"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="3">
        <location>
            <begin position="254"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY48123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="471" mass="50933" checksum="94AA901318658D37" modified="2017-04-12" version="1">MDTPTALAVDLGSSSGRIIAGTLRDGAIDEVEVHRFPHEAREVDGYLCWDLDHIWSEVVEGLREAVKQFPDAESVSVDTWGVDFALLGPDGRRLGPAVAYRDERTTRTLVRFQERLNDESAWAATGIAPATINAANQLFALIAEEPTLAEQVDQFLFLPDYFTYLLTGELVWSRSIASTSGLCRPGARDFSDEVFGALGIPRRWAGAVTPEHDVVGPCRIEGLTQLTVVRAGAHDTACAVHALQRDPSGETYFLSCGSWSVLGVLRDDPLLSDEARALGLTNEARADAGLRPLFNITGLWILQECQREWRAEGGVHDIVELIALAEDAPSTGYHIDPDEPQFALPKDMPNRVTRALAAQGADVASFTEGDIVRVILESLARRYARGVADLADLTGSAPQQLNLMGGGSRNRLLCQLTADALRVPVIAGPAEASSLGSLLAQFEIMGRVNATSRNAVIAKSARTVVFEPSHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH16</accession>
    <name>A0A1Q2CH16_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Hydroxyethylthiazole kinase</fullName>
            <ecNumber evidence="9">2.7.1.50</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">4-methyl-5-beta-hydroxyethylthiazole kinase</fullName>
            <shortName evidence="9">TH kinase</shortName>
            <shortName evidence="9">Thz kinase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">thiM</name>
        <name evidence="10" type="ORF">RPIT_11835</name>
        <name evidence="11" type="ORF">SAMN05428934_106107</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphooxyethyl)-thiazole + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24212"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17957"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Cofactor biosynthesis; thiamine diphosphate biosynthesis; 4-methyl-5-(2-phosphoethyl)-thiazole from 5-(2-hydroxyethyl)-4-methylthiazole: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Thz kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.50" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11835"/>
    <dbReference type="EnsemblBacteria" id="AQP45404">
        <property type="protein sequence ID" value="AQP45404"/>
        <property type="gene ID" value="RPIT_11835"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93041">
        <property type="protein sequence ID" value="SDY93041"/>
        <property type="gene ID" value="SAMN05428934_106107"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11835"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00139"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004417">
        <property type="term" value="F:hydroxyethylthiazole kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01170">
        <property type="entry name" value="THZ_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00228">
        <property type="entry name" value="Thz_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000417">
        <property type="entry name" value="Hyethyz_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02110">
        <property type="entry name" value="HK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000513">
        <property type="entry name" value="Thz_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01099">
        <property type="entry name" value="HYETHTZKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP45404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY93041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="266" mass="26437" checksum="92BD9C99680D4C30" modified="2017-04-12" version="1">MTVSPILTAVRSRTPLVHCMTNTVVPQITANVLLAVGAAPAMIDLPEEAEIFAGVASALLINVGNGSAEQHRAMRLAAAAAEREGTPWVLDPVAVGALPVRTQLARDLLAHRPAAIRANASEILGLAGASAGGRGVDATDTADDALAAGRELSEQTGAVIAISGPVDVVISGGRVTRISGGSPLMPLVIGTGCALGATVAAALGAVSGSGHSAHEAVVAAHALFGAAGSRAAQQTNAPGSFQVAWIDALHTLTPDEVATLVSVEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH22</accession>
    <name>A0A1Q2CH22_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein L7/L12 C-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_11795</name>
        <name evidence="4" type="ORF">SAMN05428934_106116</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11795"/>
    <dbReference type="EnsemblBacteria" id="AQP45397">
        <property type="protein sequence ID" value="AQP45397"/>
        <property type="gene ID" value="RPIT_11795"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93219">
        <property type="protein sequence ID" value="SDY93219"/>
        <property type="gene ID" value="SAMN05428934_106116"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11795"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012551">
        <property type="entry name" value="DUF1707"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_L7/L12_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08044">
        <property type="entry name" value="DUF1707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L12" evidence="2">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY93219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="201" mass="22933" checksum="4DAB387BC550D6A0" modified="2017-04-12" version="1">MTGGPHEFRIGDRERDDAVRLLSDHHSAGRLTVDEFSDRMAKALEARTMPELQGLFSDLPGPRPGAVPPMPPPPAAMEAYGAMENYGEPPTADPTPWYAQWWMILVAVGFTVVFDGSFGFIIPMMAIWLWVIYPSMQKRNRYQQVQMPRRPLTVEEQQRVMAEVRVGRKIQAIKLYRELTGAGLKEAKDTVDEWERRQIGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHA5</accession>
    <name>A0A1Q2CHA5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytochrome b5-like Heme/Steroid binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_12375</name>
        <name evidence="5" type="ORF">SAMN05428934_1061</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
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    </reference>
    <comment type="function">
        <text evidence="7 8">Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile)</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY91494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12195"/>
    <dbReference type="EnsemblBacteria" id="AQP45470">
        <property type="protein sequence ID" value="AQP45470"/>
        <property type="gene ID" value="RPIT_12195"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY91494">
        <property type="protein sequence ID" value="SDY91494"/>
        <property type="gene ID" value="SAMN05428934_10637"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12195"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07961">
        <property type="entry name" value="Anticodon_Ia_Ile_ABEc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02003">
        <property type="entry name" value="Ile_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033709">
        <property type="entry name" value="Anticodon_Ile_ABEc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023586">
        <property type="entry name" value="Ile-tRNA-ligase_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42780">
        <property type="entry name" value="PTHR42780"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 8 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="9">
        <location>
            <begin position="23"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="10">
        <location>
            <begin position="688"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="601"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="604"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP45470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY91494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="1044" mass="117240" checksum="643470035473877A" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHD8</accession>
    <name>A0A1Q2CHD8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_12225</name>
        <name evidence="4" type="ORF">SAMN05428934_10631</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY91357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12225"/>
    <dbReference type="EnsemblBacteria" id="AQP45475">
        <property type="protein sequence ID" value="AQP45475"/>
        <property type="gene ID" value="RPIT_12225"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY91357">
        <property type="protein sequence ID" value="SDY91357"/>
        <property type="gene ID" value="SAMN05428934_10631"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12225"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033186">
        <property type="entry name" value="HerA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05872">
        <property type="entry name" value="DUF853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF853" evidence="2">
        <location>
            <begin position="32"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="490"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY91357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="548" mass="59835" checksum="BBEB704F01DC5CFB" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHG4</accession>
    <name>A0A1Q2CHG4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45552">
        <property type="protein sequence ID" value="AQP45552"/>
        <property type="gene ID" value="RPIT_12670"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12670"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103647">
        <property type="entry name" value="SSF103647"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012026636" evidence="1">
        <location>
            <begin position="41"/>
            <end position="763"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="763" mass="80432" checksum="A67EBDAB0888E4DE" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHN4</accession>
    <name>A0A1Q2CHN4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycerol kinase</fullName>
            <ecNumber evidence="5">2.7.1.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP:glycerol 3-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Glycerokinase</fullName>
            <shortName evidence="5">GK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">glpK</name>
        <name evidence="9" type="ORF">RPIT_13145</name>
        <name evidence="10" type="ORF">SAMN05428934_10458</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21644"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.30"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="5">Inhibited by fructose 1,6-bisphosphate (FBP).</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the FGGY kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.30" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY76615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13145"/>
    <dbReference type="EnsemblBacteria" id="AQP45636">
        <property type="protein sequence ID" value="AQP45636"/>
        <property type="gene ID" value="RPIT_13145"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY76615">
        <property type="protein sequence ID" value="SDY76615"/>
        <property type="gene ID" value="SAMN05428934_10458"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13145"/>
    <dbReference type="UniPathway" id="UPA00618">
        <property type="reaction ID" value="UER00672"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004370">
        <property type="term" value="F:glycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00186">
        <property type="entry name" value="Glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005999">
        <property type="entry name" value="Glycerol_kin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01311">
        <property type="entry name" value="glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="5 6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="7">
        <location>
            <begin position="5"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="8">
        <location>
            <begin position="262"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="83"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="246"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="13"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="413"/>
            <end position="417"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY76615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="505" mass="55275" checksum="00FBFED50DBDCBA7" modified="2017-04-12" version="1">MNDKYVLAIDQGTTSSRAIVFDHKGTIVSVGQKEHEQIFPRAGWVEHDPKEIWANVRSVVADALSKAELNSGNIAAVGITNQRETTVVWDKNTGEPVYNAIVWQDTRTAKIVEELGGGDQNKYKDRVGLPLATYFCGPKVKWILDNVDGAREKAEAGDLVMGTMDTWVLWNMTGGTNGGIHVTDVTNASRTMLMDLKTLDWDEEIAKDMTIPMSMLPEIKSSAEVYGDGRPQGMLPGVPIAGILGDQQAATFGQACFEVGMAKNTYGTGNFMLINTGEEVVPSENGLLTTVCYKIGDKPAIYALEGSIAVTGSLVQWLRDNLKMFDSAPEVEQLAATVEDNGGAYFVPAFSGLFAPYWKADARGALVGLTRYVNRGHIARAVLEATAFQTREVLDAMEADSGVELAELKVDGGMTANETLMQFQADMLGVDVVRPVVAETTALGAAYAAGIAVGYWQGEQDVIDNWAEDKRWTPSMDEDERERLYRNWKKAVTRTFDWVDEDVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHT4</accession>
    <name>A0A1Q2CHT4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_13335</name>
        <name evidence="2" type="ORF">SAMN05428934_10420</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY75522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45672">
        <property type="protein sequence ID" value="AQP45672"/>
        <property type="gene ID" value="RPIT_13335"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY75522">
        <property type="protein sequence ID" value="SDY75522"/>
        <property type="gene ID" value="SAMN05428934_10420"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13335"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023204">
        <property type="entry name" value="SP1917_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014580">
        <property type="entry name" value="UCP033199"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09966">
        <property type="entry name" value="DUF2200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033199">
        <property type="entry name" value="UCP033199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY75522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="113" mass="13035" checksum="A6D2818BD4280ABA" modified="2017-04-12" version="1">MHRIFSVPFSSVYPHYVTKVERKGRTKEELHEVIRWLTGFNDATLQRHIDGDTTFEDFFAEATLNPNARLITGVVCGVRVEAIEDPLMQKLRYLDKLVDELAKGKAMEKVLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHT8</accession>
    <name>A0A1Q2CHT8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_13075</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13075"/>
    <dbReference type="EnsemblBacteria" id="AQP45625">
        <property type="protein sequence ID" value="AQP45625"/>
        <property type="gene ID" value="RPIT_13075"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13075"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061077">
        <property type="term" value="P:chaperone-mediated protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044609">
        <property type="entry name" value="FKBP2/11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45779">
        <property type="entry name" value="PTHR45779"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="5">
        <location>
            <begin position="34"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="123" mass="12904" checksum="A2C1E343A68564BF" modified="2017-04-12" version="1">MNEKPEVDFPGGEPPADLEIKDIVEGDGQEAKAGDTAHVHYVGVAFSSGEEFDSSWNRGAPLSFPLGAGRVIQGWDQGLQGMKVGGRRQLTIPSHLAYGDRGAGGVIAPGETLIFVCDLVGLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHZ4</accession>
    <name>A0A1Q2CHZ4_9ACTN</name>
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        <submittedName>
            <fullName evidence="2">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">RPIT_13795</name>
        <name evidence="3" type="ORF">SAMN05428934_11141</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ12353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13795"/>
    <dbReference type="EnsemblBacteria" id="AQP45746">
        <property type="protein sequence ID" value="AQP45746"/>
        <property type="gene ID" value="RPIT_13795"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12353">
        <property type="protein sequence ID" value="SDZ12353"/>
        <property type="gene ID" value="SAMN05428934_11141"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13795"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="87"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ12353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="284" mass="31262" checksum="C4F2463E3BE33D7F" modified="2017-04-12" version="1">MPDQILSPAGASQGVRGLLKRALALLGGNRPAEGATLLIYHRVGGGTTNELDLDPVDFSRQLDLLADHDVLSLDEALDRLEVGDRTPSFVLTFDDGFADVYDNAWPLLRDRRIPFTIYLATAYMGEVMVWEGATATGEPGRGLSWDQLREMVASGLCTVGNHTHNHVRPEGLTVDELDLCTRRIEQELGVTPRHFTYPWGIVVPEMEASMRARFRSASTGKLGRNTSGTNRMDLRRVPVRRTDPKSFFAAKLRGGLLAEYLYAVAVDLAKGASRRWGRVVGVGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI02</accession>
    <name>A0A1Q2CI02_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2,4-dienoyl-CoA reductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">NADH:flavin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13415</name>
        <name evidence="4" type="ORF">SAMN05428934_1045</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY75104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13415"/>
    <dbReference type="EnsemblBacteria" id="AQP45685">
        <property type="protein sequence ID" value="AQP45685"/>
        <property type="gene ID" value="RPIT_13415"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY75104">
        <property type="protein sequence ID" value="SDY75104"/>
        <property type="gene ID" value="SAMN05428934_1045"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13415"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="2">
        <location>
            <begin position="17"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY75104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="358" mass="37757" checksum="16B2F929F54F1E5C" modified="2017-04-12" version="1">MTDLSDPLVFSHGPAWRNRLALAPLTNKQSHPDGTLSDDEIRWLLARGRHGFGMTMTAAAYVAPAGKAWQGQLGISEDAHLPGLTRLADGLRDAGSASIVQLHHGGTQANPSVSGEELVGPSADPERGARALTTDEVRRTVDDFAAAAARAERAGFDGVQLHGAHGYLLCEFLSSRNVRDDGYGGDLEGKARIIRESIAAVREATSSDFHVALRISTERLGLDTDEMAELSAQLMAEGGLDHLELSLWDVTKLPEGAEPGAPSLLSHFIDLPRGSTRLGIAGKVGSGPAAVAALATGVDFVTIGRAAIADQRIAERTLADPDYPGPAFPVTKDVLRDNCVGEAFVDYFSAGWPQLVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI29</accession>
    <name>A0A1Q2CI29_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase involved in cell wall bisynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13840</name>
        <name evidence="3" type="ORF">SAMN05428934_11132</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13840"/>
    <dbReference type="EnsemblBacteria" id="AQP45754">
        <property type="protein sequence ID" value="AQP45754"/>
        <property type="gene ID" value="RPIT_13840"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12178">
        <property type="protein sequence ID" value="SDZ12178"/>
        <property type="gene ID" value="SAMN05428934_11132"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13840"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="24"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="360"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ12178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="703" mass="78121" checksum="EF7FDC4C99DD1567" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI57</accession>
    <name>A0A1Q2CI57_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF6458 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_14170</name>
        <name evidence="5" type="ORF">SAMN05428934_11216</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ14475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45808">
        <property type="protein sequence ID" value="AQP45808"/>
        <property type="gene ID" value="RPIT_14170"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ14475">
        <property type="protein sequence ID" value="SDZ14475"/>
        <property type="gene ID" value="SAMN05428934_11216"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14170"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045597">
        <property type="entry name" value="DUF6458"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20059">
        <property type="entry name" value="DUF6458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6458" evidence="3">
        <location>
            <begin position="2"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ14475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="80" mass="8532" checksum="C1DCC878505752EB" modified="2017-04-12" version="1">MRIGSAIVLIAVGAILAWAVNAEIPYISLDLVGYILIGAGVIGLIWALMASQRSRVTESRVVQDPNTGETVRRSESHDGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI99</accession>
    <name>A0A1Q2CI99_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">5,10-methylene tetrahydromethanopterin reductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Putative luciferase-like monooxygenase, FMN-dependent, CE1758 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_14260</name>
        <name evidence="4" type="ORF">SAMN05428934_11234</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ14839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14260"/>
    <dbReference type="EnsemblBacteria" id="AQP45824">
        <property type="protein sequence ID" value="AQP45824"/>
        <property type="gene ID" value="RPIT_14260"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ14839">
        <property type="protein sequence ID" value="SDZ14839"/>
        <property type="gene ID" value="SAMN05428934_11234"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14260"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023934">
        <property type="entry name" value="LLM_FMN-dep_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04036">
        <property type="entry name" value="LLM_CE1758_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ14839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="385" mass="42809" checksum="787B0E4E02A2182B" modified="2017-04-12" version="1">MQFGIFTIGDITPDPTTGRTPTEHERIKATVELALKAEEVGLDVFAAGQHHNPPFVATSPTTTLAFIAAKTERIILSTATTLITTTDPVRIAEDYAQLQHLAEGRVDLTLGRGNTGPVYPWFGQDIRDGIALAIENYELLHRLWREDVVNWQGKFRTPLHGFTATPRPLDGVAPFVWHGSIRSPEIAEQAAYYGDGFFHNNIFWPPSHTRRMVELYRRRYEHYGHGRADQAIVGLGGQVFMRKNSQDAIREFRPYFDNAPVYGGGPSLEDFSRETPLTVGSPQQVIERVLGFREYAGDYQRQLFLMDHAGLPQKTVLEQLDLLGEEVVPVLRQEFAKLKPAHVPDAPTHASLVAAAGAPDPPAERGPSADRWTGTRAEDGNRLTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIA2</accession>
    <name>A0A1Q2CIA2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_14430</name>
        <name evidence="2" type="ORF">SAMN05428934_109130</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ07084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45856">
        <property type="protein sequence ID" value="AQP45856"/>
        <property type="gene ID" value="RPIT_14430"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ07084">
        <property type="protein sequence ID" value="SDZ07084"/>
        <property type="gene ID" value="SAMN05428934_109130"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14430"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ07084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="261" mass="29718" checksum="4BF9DB07FAFCA390" modified="2017-04-12" version="1">MAFDLDKFTETSEAVAWDDLDFDTFDDQPLDADTLRSLRYMCDVEYHTSCFLRDLLVTRSRREPEAAGFMTMWNREEFWHGEALSAVLQRHGIVVDYDELKAKRVKLGWQFALGPLKQSVMSNLVGKNFIAVHMAWGAANELSAVAAYRRMADMTSHPALSPLLRRIAQQETRHVAFYTTQARAAMEESETAQKLVRLVLANAWRPVGSGMMDESEVQHVMSHLFQGHMDVLDKVDLRVQKLPGLEGLTIFRTAFTKMGIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CID3</accession>
    <name>A0A1Q2CID3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14305</name>
        <name evidence="3" type="ORF">SAMN05428934_11243</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ15021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45833">
        <property type="protein sequence ID" value="AQP45833"/>
        <property type="gene ID" value="RPIT_14305"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ15021">
        <property type="protein sequence ID" value="SDZ15021"/>
        <property type="gene ID" value="SAMN05428934_11243"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14305"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045393">
        <property type="entry name" value="DUF6518"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20128">
        <property type="entry name" value="DUF6518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ15021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="196" mass="19554" checksum="625D7AFED5BCD62F" modified="2017-04-12" version="1">MSARAAALALGGGLVAGVVMSFGQTVAPEPIAPLFNSAAPVVALAAAVALAGRGALTHVLFGASAGPLAMVGYYATTHLRGFGVSLQMVAFWSVAGVVSGAAMGLAVWALRRRAAPAWRVPAAALFPGVAIGEAAHGLVRISDTTPAAYWAGLALLGAVILAWLARSFLDTTLQRTLAVGFTAAAAAALFVLYGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIM3</accession>
    <name>A0A1Q2CIM3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45900">
        <property type="protein sequence ID" value="AQP45900"/>
        <property type="gene ID" value="RPIT_14695"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14695"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="70" mass="7458" checksum="12831842620D33A1" modified="2017-04-12" version="1">MRRSLTLPIGNIFAPGSTPSRGWLLLTTTSSSTTVVSGLPEITSMLPGGDIRTDAPRAKNQLKTRSRGCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIP1</accession>
    <name>A0A1Q2CIP1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_02525</name>
        <name evidence="2" type="ORF">SAMN05428934_101105</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY25398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02525"/>
    <dbReference type="EnsemblBacteria" id="AQP45977">
        <property type="protein sequence ID" value="AQP45977"/>
        <property type="gene ID" value="RPIT_02525"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY25398">
        <property type="protein sequence ID" value="SDY25398"/>
        <property type="gene ID" value="SAMN05428934_101105"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02525"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY25398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="409" mass="42044" checksum="37DD543AA8E67FB5" modified="2017-04-12" version="1">MGVSERQTRHRASTEAVLDHAWDSGAFGADHVISALGMTRSTALSALDELIDVGLIEELTSSAGPAQRLGRPARRFELRGEAGLIVGLDAGGRRFSAIAADLSGRILAREHLDLTSFFELEAPDPATRHTAALRAIDAVLAAAGGSRDEVIAVGVGVPAPVDGQGASPAHPSGFWSYMNAGLREALSGEFPVVRVENDASLAAVAEGSLGEAQGREHYVAMLSGLRLGSGVVLEGRLVRGAHGGVGELEALAYVPGVGGTWGLGYLAEQWLREQLGMGAIPADHPWAALSGGAVTGEAVLSRARLADPVARPLVEELGGTLGRICTVVSRFFDPEVIVVCGAIAGTLGEVIEIAVAHVAGELELPPPGIVASGLGGDVVSLGALSAARESARQVVLPLLTARRLAARTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIS4</accession>
    <name>A0A1Q2CIS4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative 3-methyladenine DNA glycosylase</fullName>
            <ecNumber evidence="5">3.2.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_01985</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the DNA glycosylase MPG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.-" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01985"/>
    <dbReference type="EnsemblBacteria" id="AQP45973">
        <property type="protein sequence ID" value="AQP45973"/>
        <property type="gene ID" value="RPIT_01985"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01985"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003905">
        <property type="term" value="F:alkylbase DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00540">
        <property type="entry name" value="AAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00527">
        <property type="entry name" value="3MGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003180">
        <property type="entry name" value="MPG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036995">
        <property type="entry name" value="MPG_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10429">
        <property type="entry name" value="PTHR10429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02245">
        <property type="entry name" value="Pur_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="SSF50486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00567">
        <property type="entry name" value="3mg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="191" mass="19844" checksum="CC69D0C1B73C0D57" modified="2017-04-12" version="1">MQALDSVAKEARALLGGHLTVDRDPGPVTLRITEVEAYAGPHDPASHAYRGPSARNQAMFGPAGHAYVYRHMGLHTCFNAVVGPPGTPTGLLIRAGEVIDGADIARARRSERGVTRTDLDLASGPARLTVALGITLDDNGAALDGSSGITLLPRSGPAPTIVSGPRIGVGAARDFPLRFSIADDPTVSRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIY9</accession>
    <name>A0A1Q2CIY9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF305 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_07245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07245"/>
    <dbReference type="EnsemblBacteria" id="AQP46072">
        <property type="protein sequence ID" value="AQP46072"/>
        <property type="gene ID" value="RPIT_07245"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07245"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005183">
        <property type="entry name" value="DUF305"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03713">
        <property type="entry name" value="DUF305"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="DUF305" evidence="2">
        <location>
            <begin position="91"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="145" mass="16429" checksum="CF9EFE58376BD394" modified="2017-04-12" version="1">MYWEFGAILLVNLGLMWALSMSMVRSLDHFYFNPSNLYMAVLMVAAMAVLMTVGMWSMLKNKTLNIILLVGFLALFLAAFFTGRNEVGVGDEGFLTSMIPHHSRAILVCQEASITDPEIEQLCSEIVEAQEREIAQMKEILKRYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ06</accession>
    <name>A0A1Q2CJ06_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09035"/>
    <dbReference type="EnsemblBacteria" id="AQP46097">
        <property type="protein sequence ID" value="AQP46097"/>
        <property type="gene ID" value="RPIT_09035"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09035"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026898">
        <property type="entry name" value="PrsW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36844">
        <property type="entry name" value="PTHR36844"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13367">
        <property type="entry name" value="PrsW-protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="425" mass="46968" checksum="D80ED901B3AA6B76" modified="2017-04-12" version="1">MFWVTAVLLPLYAWMLYDQYWMLHPPETFDDGTSTLGITNEAFELAAFWASWTALAYATLFIWLDRFRASSPLVWVLTFLWGACASTWISIYVNSWAGQMMSTTQADAFAGSRAAVFSAPFIEELAKASILVLLVILMRRRIVSRLSMVALAGLSAVGFAFTENVIYYARVWMQATNDISIADPEATMLELVRLRGIYTSFGHPLFTLFTASGFIIGLSARSKIVRVLAPLGGFLLACAGHMLFNGLASTNATENLRPAWFLALALVAVIIISLVVSVVGNGQLIRARLTDFQRAGWMSERDVEVFGGPLRRAKLLLYALFRGPRTWWRTAALVRRYTELAYLRDAMTRGTVDAAGDARAHDIIEQIHHLRPIALTDTRGLTLIQPRARKPEPPPPADTAPGPLTSDYLPPQAPGPAGVGGNWPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ41</accession>
    <name>A0A1Q2CJ41_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Enoyl-CoA hydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_10390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10390"/>
    <dbReference type="EnsemblBacteria" id="AQP46122">
        <property type="protein sequence ID" value="AQP46122"/>
        <property type="gene ID" value="RPIT_10390"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10390"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="261" mass="27448" checksum="33AC6AC7C63C6414" modified="2017-04-12" version="1">MTESILLSVEDGLARLTLNRPERLNAFDASMAAAWTRVVQDVVRRDDVGAVLLTGAGTSFCAGGDVAQMATTMSDGGEIAQLATTINRGITALTASDKPVVAAIHGATAGGGLGIMLATDYVVAGRSSRVGSRYANVGLTPDLSVTAHLARAVGERRALQLVLSDLMLTADEALRWGLVAEVVDDDDVVTRAEQVAAVWLNGATKAYGRAKQLIRQSPFNSFDVQLEEEARAIGESFDTSEAKRRIAAFAEASSRKRGGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ49</accession>
    <name>A0A1Q2CJ49_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD-dependent protein deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_13370</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13370"/>
    <dbReference type="EnsemblBacteria" id="AQP46168">
        <property type="protein sequence ID" value="AQP46168"/>
        <property type="gene ID" value="RPIT_13370"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13370"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="3">
        <location>
            <begin position="36"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP46168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="312" mass="33600" checksum="5395E81699AB3C95" modified="2017-04-12" version="1">MPDVGGWFRTARDGGVATHGRWGAVAGPFGLVSTDDELRAALDLLSDGPTMVLSGAGMSTGSGLPDYRGPDAVPRSPMTYDEFVSSDLSRRRYWARSTVGWRWFRQAEPGVTHVALAELGGMLDVVGVVTQNVDGLHTRAGSAPVVDLHGSLDRVVCLSCGAVTGRERLQEELLALNPRFAAQLDDLAEEARSAPDGDAEVDRTETFRYPDCEVCGGVLKPDVVFFGENVARDVVARANDLFERAGSLLVVGTSLTVMSGLRFVRRAAKDGKPVVIVGDGATRGDELATMRLHGRLENVLPRWVDWLRELAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBD5</accession>
    <name>A0A1Q2CBD5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytidine and deoxycytidylate deaminase zinc-binding region</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">tRNA-specific adenosine deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00080</name>
        <name evidence="3" type="ORF">SAMN05428934_10929</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00080"/>
    <dbReference type="EnsemblBacteria" id="AQP43416">
        <property type="protein sequence ID" value="AQP43416"/>
        <property type="gene ID" value="RPIT_00080"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05123">
        <property type="protein sequence ID" value="SDZ05123"/>
        <property type="gene ID" value="SAMN05428934_10929"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00080"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ05123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="159" mass="16952" checksum="5F1622E750B25279" modified="2017-04-12" version="1">MITDADRRFLSRAVELAELALSRGDEPFGSVLVSAAGEVLFEDHNHVAAGDHTQHPEFAIARWAAENLTPDERAAATVYTSGEHCPMCSAAHGWVGLGRIVYASSSAQLSQWLRDLGCPDAPVAALPIQQVVPAAVVDGPDPELAERVHALHARRTGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBE1</accession>
    <name>A0A1Q2CBE1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43418">
        <property type="protein sequence ID" value="AQP43418"/>
        <property type="gene ID" value="RPIT_00090"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00090"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="131" mass="14066" checksum="433CD2ACD3E67E86" modified="2017-04-12" version="1">MLMAAIGSALTACQESDDMSQLPILTDDPMADEALLGLRLLSADEHGYRTALGKPRYAEVTRTFAVGSDPDAILAAAVEEAGASGWAEATPLNQDLMVWQGYKEEPRRTCSISLDRAAEELRLTLTVVEAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
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    <name>A0A1Q2CBQ3_9ACTN</name>
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        <submittedName>
            <fullName evidence="3">16S rRNA (Guanine1207-N2)-methyltransferase</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">RPIT_00780</name>
        <name evidence="3" type="ORF">SAMN05428934_105109</name>
    </gene>
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
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            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="SAMN05428934_105109"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
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        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044260">
        <property type="term" value="P:cellular macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043412">
        <property type="term" value="P:macromolecule modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTS" evidence="1">
        <location>
            <begin position="157"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY86322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="331" mass="35325" checksum="EC6CBB45A0744B14" modified="2017-04-12" version="1">MRDVVDDLIWDEAPKEASAVALLDAPALVEDALTLTDDVRVFCDDWRDAALVPSELLVEHPTDLAGVDLALARLPKSLAALDEQAALVQGAQDVTFVGGARIKHMNLTMNEVLGKHFTAVAASLGRSKSRVLRAWGPNGLESDWPKVRDHDDLGFAVAAHGATFGGTKIDPGSRLLLAALRGAGRTPGLEGEDVLDFGCGNGTLAMWLARDGRTVSARDVSWSAVAGTVVAAEVNGVEVDATWGDGLADYPDDSFDAIVTNPPFHKGFAKDSADTLAMFDDAARVLRPGGQLWCVFNSHLPWRKELNVRVGRTQVALQDPHYTATVTVARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBU4</accession>
    <name>A0A1Q2CBU4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">D-lactate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_00680</name>
        <name evidence="7" type="ORF">SAMN05428934_10589</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY85806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00680"/>
    <dbReference type="EnsemblBacteria" id="AQP43515">
        <property type="protein sequence ID" value="AQP43515"/>
        <property type="gene ID" value="RPIT_00680"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY85806">
        <property type="protein sequence ID" value="SDY85806"/>
        <property type="gene ID" value="SAMN05428934_10589"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00680"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Cys_rich_dom"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
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        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="25"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="519"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY85806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="914" mass="99013" checksum="89DDD295EBB7C21A" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBX4</accession>
    <name>A0A1Q2CBX4_9ACTN</name>
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        <submittedName>
            <fullName evidence="4">DNA binding domain-containing protein, excisionase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01160</name>
        <name evidence="4" type="ORF">SAMN05428934_105182</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY88269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43601">
        <property type="protein sequence ID" value="AQP43601"/>
        <property type="gene ID" value="RPIT_01160"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY88269">
        <property type="protein sequence ID" value="SDY88269"/>
        <property type="gene ID" value="SAMN05428934_105182"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01160"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010093">
        <property type="entry name" value="SinI_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01764">
        <property type="entry name" value="excise"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="2">
        <location>
            <begin position="16"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY88269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="85" mass="9793" checksum="C53A97608E1A2E0B" modified="2017-04-12" version="1">MSLPISHTWGQPVPEWLSLQQAAAVYGVSVDTLRRRVASGKLRASRFGVRLTRVRVEDLDRLFRPIPTGDDLTQRRARARNQRPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC03</accession>
    <name>A0A1Q2CC03_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pilus assembly protein CpaF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01405</name>
        <name evidence="4" type="ORF">SAMN05428934_10829</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01405"/>
    <dbReference type="EnsemblBacteria" id="AQP43636">
        <property type="protein sequence ID" value="AQP43636"/>
        <property type="gene ID" value="RPIT_01405"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01469">
        <property type="protein sequence ID" value="SDZ01469"/>
        <property type="gene ID" value="SAMN05428934_10829"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01405"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022399">
        <property type="entry name" value="HlxAse/secretion_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03819">
        <property type="entry name" value="heli_sec_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="59"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ01469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="381" mass="39677" checksum="FEBF42BAD65618F8" modified="2017-04-12" version="1">MTDPDLEALQANLAALGRPFTPRDVAAALRTLGAAVSDARVRELLDELRRHSTGAGPLDSLLRDPGVSDVVVNGPDDVFVDRGVGLEKTSVGFVDDEQVRRLAIRLAAAAGRRLDDASPFVDGRLPGGVRVHAVLAPVASPGTCVSLRVPAARGFTLDDLVAAGSVGTEGAGLLASIVARRVPFLISGGTGSGKTTLLAALLGLVPAAERIVLVEDARELEPAHPHCVRLEGRPPNSEGAGAITLTTLVRQALRMRPDRVVLGEARGAEVIDLLTALNTGHEGGCGTIHANSVVDVPARLEALASLGGLGREACHAQIAAALRVVIHLRRDHAGRRKVQQIGVFRRGADGLVEVETAVVLEGTEPTWGPAAEALRRLVESC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC52</accession>
    <name>A0A1Q2CC52_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9 10">Cytochrome C biogenesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_01720</name>
        <name evidence="10" type="ORF">SAMN05428934_10892</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01720"/>
    <dbReference type="EnsemblBacteria" id="AQP43684">
        <property type="protein sequence ID" value="AQP43684"/>
        <property type="gene ID" value="RPIT_01720"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02674">
        <property type="protein sequence ID" value="SDZ02674"/>
        <property type="gene ID" value="SAMN05428934_10892"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01720"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023494">
        <property type="entry name" value="Cyt_c_bgen_Ccs1/CcsB/ResB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007816">
        <property type="entry name" value="ResB-like_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31566">
        <property type="entry name" value="PTHR31566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05140">
        <property type="entry name" value="ResB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="440"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="ResB" evidence="8">
        <location>
            <begin position="24"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="502"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP43684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ02674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="542" mass="57938" checksum="19A13F4AAD77A14E" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC58</accession>
    <name>A0A1Q2CC58_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-aminoacyl-tRNA deacylase</fullName>
            <shortName evidence="1">DTD</shortName>
            <ecNumber evidence="1">3.1.1.96</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Gly-tRNA(Ala) deacylase</fullName>
            <ecNumber evidence="1">3.1.1.-</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dtd</name>
        <name evidence="2" type="ORF">RPIT_01800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a D-aminoacyl-tRNA + H2O = a D-alpha-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13953"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:10124"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59871"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:79333"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>glycyl-tRNA(Ala) + H2O = glycine + H(+) + tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:53744"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:13640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DTD family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.96" evidence="1"/>
    <dbReference type="EC" id="3.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01800"/>
    <dbReference type="EnsemblBacteria" id="AQP43698">
        <property type="protein sequence ID" value="AQP43698"/>
        <property type="gene ID" value="RPIT_01800"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01800"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051499">
        <property type="term" value="F:D-aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106026">
        <property type="term" value="F:Gly-tRNA(Ala) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043908">
        <property type="term" value="F:Ser(Gly)-tRNA(Ala) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00518">
        <property type="entry name" value="Deacylase_Dtd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003732">
        <property type="entry name" value="Daa-tRNA_deacyls_DTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023509">
        <property type="entry name" value="DTD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472">
        <property type="entry name" value="PTHR10472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02580">
        <property type="entry name" value="Tyr_Deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69500">
        <property type="entry name" value="SSF69500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00256">
        <property type="entry name" value="TIGR00256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0820">tRNA-binding</keyword>
    <feature type="short sequence motif" description="Gly-cisPro motif, important for rejection of L-amino acids" evidence="1">
        <location>
            <begin position="133"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="145" mass="15602" checksum="126AEE788C3C14F5" modified="2017-04-12" version="1">MRVVVTRATEASVEVEGQVIAELPRPGLLVLAGVGHDDGSDDAAALARKIWGLRILDDEASASDLNAPILVVSQFTLFASTRKGRRPSWSRAAPGEISEPLVERLCVELERLGATVQRGRFGAHMKVSSVNDGPITITIDTKSWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC70</accession>
    <name>A0A1Q2CC70_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alpha-glucoside transport system permease protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_01895</name>
        <name evidence="8" type="ORF">SAMN05428934_108127</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ03384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01895"/>
    <dbReference type="EnsemblBacteria" id="AQP43713">
        <property type="protein sequence ID" value="AQP43713"/>
        <property type="gene ID" value="RPIT_01895"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ03384">
        <property type="protein sequence ID" value="SDZ03384"/>
        <property type="gene ID" value="SAMN05428934_108127"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01895"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
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        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="304"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
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        <location>
            <begin position="163"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ03384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="394" mass="43166" checksum="7F8107C9DB6CBAA1" modified="2017-04-12" version="1">MSTPSATPPPVSGVPDSPDPSGPPTAATTGLQPLKVIGGAVGAAFTLWFMGNLFLAFAYYPQWFFDSKILMAILALIVGVGGAAIFFWFLNMAIEGLPRSLEHGLMPYAFLLPGFSLIGLMLLYPTIQTINYSFANRNSTEYMDPPWANYTFLFQSSEFWSAIFNNVLWIAIVPAVTVALGVIVAVLSDKLSAAGEKWSKSFIFLPMAISFVAASAIWSTTVYGYQPPGQPQTAILNAMRTATGNEPLAWLSIDTGRLNSLLLMVILIWLQVGFAMVLLSSAIKGVPEDTIEAARIDGASEFKIFFQVIIPQIMGTIITVFITVLILVMKVFDIIYVLTNGRNNTDVIANMFFREMFTNLQAGRATAIVVVLLVAILPVLIYQVRLFRQQESMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCC8</accession>
    <name>A0A1Q2CCC8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02215</name>
        <name evidence="3" type="ORF">SAMN05428934_10142</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY23572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43773">
        <property type="protein sequence ID" value="AQP43773"/>
        <property type="gene ID" value="RPIT_02215"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY23572">
        <property type="protein sequence ID" value="SDY23572"/>
        <property type="gene ID" value="SAMN05428934_10142"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02215"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY23572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="146" mass="15406" checksum="DC70D58D61D8E5ED" modified="2017-04-12" version="1">MTDSQHEDGYAWTWEPAVGILTTVALLAVVAVQVGRSLTLAAAGAGWHWPPLAVLVPSSWGILTGNLHAGLTTHGTDAVWVAWAIAAAVFIAGLTAAIVLALRVTAGRRFKGMATTGQAEQLLGLGRLRANRAVIRPDLCRKGHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCC9</accession>
    <name>A0A1Q2CCC9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02195</name>
        <name evidence="3" type="ORF">SAMN05428934_10138</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY23451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02195"/>
    <dbReference type="EnsemblBacteria" id="AQP43769">
        <property type="protein sequence ID" value="AQP43769"/>
        <property type="gene ID" value="RPIT_02195"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY23451">
        <property type="protein sequence ID" value="SDY23451"/>
        <property type="gene ID" value="SAMN05428934_10138"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02195"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY23451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="501" mass="53597" checksum="8E84AFBD028C0986" modified="2017-04-12" version="1">MAARTFDAFTTPKAGVIWGLTVPQLLFLSVATFPAWMAISSQRWLAGIMWVPVWLLLLFLTVVPLGGRSAVGWLAAAASFAVAGLSGWLAFRSKAATGTLRDLDELDMPGALTGVEVLDGPPIGLEQRRVAVIKHCAARTWAITARIEHDGIAMATDALCNRYADGLTELLDTAARGELISEIHLMVRTTPDDCTERELWLRANITADAPVTSVATQIEHLRWSQAGVRTEAFITLVIPEARLSKEARHMGGATDGRMNTLLSLAAEIGAVVTGPIGARNIEWLTSPELAQVVRLGFAPGDRAGLVAAEHDATEDSSVNPGVPWALAGPSQAYAAVRHYAHDAWATVTATVKLPERGASMGGWGHVLAPSEAVERRSVAVVFPIEKQSAADRKAAQQEFGQSLGQGLKDRLGVRTGAKDHRRQAKLDRVEVQLAMGATMSHPYALCSTTIPATAPVAEFGRRLDAAIRRGGMAPQRLDMSQDLAFVTATLPLGVSLTTRHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCF1</accession>
    <name>A0A1Q2CCF1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_02365</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43803">
        <property type="protein sequence ID" value="AQP43803"/>
        <property type="gene ID" value="RPIT_02365"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02365"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="249" mass="26852" checksum="A6AC10EB194309E3" modified="2017-04-12" version="1">MNAVTWLWRQFNEERWPALILALSVALLAAVAGVTPRLMSDLDDRQLGQALAGLSAIQGDVQASWAHSQAVGPSGPDGVDDPWPARLEAARAIRDEQPEPLRSLLADPEFVGRANREVELVPEPETGYYLAVLALLVYPHLSDHAILVDGAWPVFGTGSERTQVAVLEGVAEKMRWTVGSSIGEDYVVSATFRPADPSAQRWEHVPLGRTYTEPLDPNLGVAMNAGLFLPETYTPRPGTSGRPAAGTQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCH2</accession>
    <name>A0A1Q2CCH2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoenolpyruvate-protein phosphotransferase</fullName>
            <ecNumber evidence="4">2.7.3.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Phosphotransferase system, enzyme I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_02065</name>
        <name evidence="12" type="ORF">SAMN05428934_10110</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl-[protein] + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:23880"/>
            <dbReference type="Rhea" id="RHEA-COMP:9745"/>
            <dbReference type="Rhea" id="RHEA-COMP:9746"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:64837"/>
            <dbReference type="EC" id="2.7.3.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 4 7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.7.3.9" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY22594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02065"/>
    <dbReference type="EnsemblBacteria" id="AQP43745">
        <property type="protein sequence ID" value="AQP43745"/>
        <property type="gene ID" value="RPIT_02065"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY22594">
        <property type="protein sequence ID" value="SDY22594"/>
        <property type="gene ID" value="SAMN05428934_10110"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02065"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008965">
        <property type="term" value="F:phosphoenolpyruvate-protein phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024692">
        <property type="entry name" value="PTS_EI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008731">
        <property type="entry name" value="PTS_EIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036618">
        <property type="entry name" value="PtsI_HPr-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05524">
        <property type="entry name" value="PEP-utilisers_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000732">
        <property type="entry name" value="PTS_enzyme_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47831">
        <property type="entry name" value="SSF47831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="11" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PEP-utilisers_N" evidence="10">
        <location>
            <begin position="7"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="8">
        <location>
            <begin position="152"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="9">
        <location>
            <begin position="252"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="PEP binding" evidence="6">
        <location>
            <begin position="435"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="5">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="483"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="412"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="436"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP43745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY22594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="552" mass="57136" checksum="03BB86B907F61B7B" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCI3</accession>
    <name>A0A1Q2CCI3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glucohydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Oligo-1,6-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_02520</name>
        <name evidence="5" type="ORF">SAMN05428934_101103</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY25336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02520"/>
    <dbReference type="EnsemblBacteria" id="AQP43829">
        <property type="protein sequence ID" value="AQP43829"/>
        <property type="gene ID" value="RPIT_02520"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY25336">
        <property type="protein sequence ID" value="SDY25336"/>
        <property type="gene ID" value="SAMN05428934_101103"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02520"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022567">
        <property type="entry name" value="DUF3459"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11941">
        <property type="entry name" value="DUF3459"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="3">
        <location>
            <begin position="25"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY25336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="574" mass="63985" checksum="028899471EA9D282" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCN2</accession>
    <name>A0A1Q2CCN2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase</fullName>
            <shortName evidence="3">SEPHCHC synthase</shortName>
            <ecNumber evidence="3">2.2.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Menaquinone biosynthesis protein MenD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">menD</name>
        <name evidence="5" type="ORF">RPIT_02585</name>
        <name evidence="6" type="ORF">SAMN05428934_101117</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2-oxoglutarate + H(+) + isochorismate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25593"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29780"/>
            <dbReference type="ChEBI" id="CHEBI:58818"/>
            <dbReference type="EC" id="2.2.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="3">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 2/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPP enzyme family. MenD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.9" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY25781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02585"/>
    <dbReference type="EnsemblBacteria" id="AQP43840">
        <property type="protein sequence ID" value="AQP43840"/>
        <property type="gene ID" value="RPIT_02585"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY25781">
        <property type="protein sequence ID" value="SDY25781"/>
        <property type="gene ID" value="SAMN05428934_101117"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02585"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00164"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070204">
        <property type="term" value="F:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01659">
        <property type="entry name" value="MenD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004433">
        <property type="entry name" value="MenaQ_synth_MenD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42916">
        <property type="entry name" value="PTHR42916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004983">
        <property type="entry name" value="MenD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00173">
        <property type="entry name" value="menD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 3" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="4">
        <location>
            <begin position="6"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY25781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="509" mass="52388" checksum="56281F50485514E8" modified="2017-04-12" version="1">MSSIEMGAAIVDALVGVGVRDVVLAPGSRSAPLALAVDRAAADHRVRLHVRIDERVAGFTALGLAKAGQQPVAVVTTSGTAVANLAPAAMEARASGVPLVLITADRPAHLVGTGANQVADQVGAFGASALGVVRLSSESGDAAAWAAGVHRAVTLASGKLSGEPGPVQLNVEFAPPLVGPLPAAVQRVLDVHAESGPTQPHVLEHPARTVVLAGDATPQVGAEARALAELTRSPLLAEPSSNARAGECAIAAYREVLAELAPEIERVVVFGHPTLSRPVVSLLSRDDVELVVVTDRATWPDPGHRATLVARAVEIPTQDDGWLDRWQRADVRRSNGPQQFIADEVVSCAGPDTNLVFGSSSIIRAADLSPVAPRPPLVYANRGVAGIDGTVSTAVGIGLATGRPTTVLLGDLTAQHDLGGWVKPTLEPWPDLRVVVADDDGGSIFHGLEQGAPEFDGSFERVFGTPQGLDLVAVASALGWTAVRVQDRGGLVKALSSDADFVVVSVPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCQ0</accession>
    <name>A0A1Q2CCQ0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">50S ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rplA</name>
        <name evidence="11" type="ORF">RPIT_02865</name>
        <name evidence="12" type="ORF">SAMN05428934_101173</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9 10">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY27360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02865"/>
    <dbReference type="EnsemblBacteria" id="AQP43884">
        <property type="protein sequence ID" value="AQP43884"/>
        <property type="gene ID" value="RPIT_02865"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY27360">
        <property type="protein sequence ID" value="SDY27360"/>
        <property type="gene ID" value="SAMN05428934_101173"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02865"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01318_B">
        <property type="entry name" value="Ribosomal_L1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005878">
        <property type="entry name" value="Ribosom_L1_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_L1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_L1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_L1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_L1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023673">
        <property type="entry name" value="Ribosomal_L1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="SSF56808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01169">
        <property type="entry name" value="rplA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01199">
        <property type="entry name" value="RIBOSOMAL_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0678">Repressor</keyword>
    <keyword evidence="8 9 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 9 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 9" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="3 9" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP43884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY27360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="233" mass="25176" checksum="A85236C12EEABC9F" modified="2017-04-12" version="1">MKHSKAYRSAAEKRDDAQLYTPEEALRLVKEMASAKFDEAIDVAVRLGVDPRKADQMVRGTVNLPHGTGKTARVLVFAAGEKADAAREAGADEVGTDELVEKVAGGYLDFDAVVATPDMMGKVGRLGRVLGPRGLMPNPKTGTVTMDVAKAVSDIKGGKIEFRVDRHANLQFLIGKASFPQEHLVDNYFAVLEEILRLKPSSSKGRYLRKIAVSATMSPSVHVDQSATKPAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCT1</accession>
    <name>A0A1Q2CCT1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsJ</name>
        <name evidence="6" type="ORF">RPIT_03035</name>
        <name evidence="7" type="ORF">SAMN05428934_101208</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the binding of tRNA to the ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY28501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03035"/>
    <dbReference type="EnsemblBacteria" id="AQP43914">
        <property type="protein sequence ID" value="AQP43914"/>
        <property type="gene ID" value="RPIT_03035"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY28501">
        <property type="protein sequence ID" value="SDY28501"/>
        <property type="gene ID" value="SAMN05428934_101208"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03035"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018268">
        <property type="entry name" value="Ribosomal_S10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_S10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_S10_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="PTHR11700"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="SSF54999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01049">
        <property type="entry name" value="rpsJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00361">
        <property type="entry name" value="RIBOSOMAL_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_S10" evidence="5">
        <location>
            <begin position="7"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY28501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="103" mass="11742" checksum="3015D79C527DBBD5" modified="2017-04-12" version="1">MAGQRIRIRLRAYDHEVIDSSARKIVDTVTRTGAKVAGPVPLPTEKNVFCVIRSPHKYKDSREHFEMRTHKRLIDILDPTPKTVDSLMRLDLPAGVDIEIKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCV7</accession>
    <name>A0A1Q2CCV7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diaminopimelate decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03125</name>
        <name evidence="3" type="ORF">SAMN05428934_101226</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03125"/>
    <dbReference type="EnsemblBacteria" id="AQP43931">
        <property type="protein sequence ID" value="AQP43931"/>
        <property type="gene ID" value="RPIT_03125"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29047">
        <property type="protein sequence ID" value="SDY29047"/>
        <property type="gene ID" value="SAMN05428934_101226"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03125"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022657">
        <property type="entry name" value="De-COase2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022653">
        <property type="entry name" value="De-COase2_pyr-phos_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00878">
        <property type="entry name" value="ODR_DC_2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00879">
        <property type="entry name" value="ODR_DC_2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="1">
        <location>
            <begin position="65"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY29047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="448" mass="48308" checksum="D188C0DFB0E72130" modified="2017-04-12" version="1">MNTAVHGAPPLTGRREPWMDELLGDPETVTGLLDQFGSPVNVLDPSPLGRNAAELVAAGRESGVETRVFFARKANKTHALVKRAIEDGHGVDVASHAELRQVLDLGMPPARIIVSAAVKTDQLLALAADSGATISVDHVSELRRIERLASPGRLVAVAPRLAPDPASGVPPTRFGELRDTWIAALSEVQPGVSVTGLHVHLHGYAVADRATAIAESVRMADELRSLGHAPTFLDLGGGVPMSYLTDETQWREFWDVLGAGGEPESITWRDHRLGTVYPYYQAPTRGEWLRELLSARPESGDTCAGLLRRAGLALHLEPGRSLADGCGVTLARVAFIKRRSDGVPLIGLEMNRTQCRSTSDDFMVDPVLVRTNAPGEPLDGFLVGAYCIEDEVILRRRMHFPHGVAAGDVIALINTGGYLMHILESASHQLPLAKNVVWPSLELDGIDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCV9</accession>
    <name>A0A1Q2CCV9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">30S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpsC</name>
        <name evidence="13" type="ORF">RPIT_03070</name>
        <name evidence="14" type="ORF">SAMN05428934_101215</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 10">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY28717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03070"/>
    <dbReference type="EnsemblBacteria" id="AQP43920">
        <property type="protein sequence ID" value="AQP43920"/>
        <property type="gene ID" value="RPIT_03070"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY28717">
        <property type="protein sequence ID" value="SDY28717"/>
        <property type="gene ID" value="SAMN05428934_101215"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03070"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01309_B">
        <property type="entry name" value="Ribosomal_S3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005704">
        <property type="entry name" value="Ribosomal_S3_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_S3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_S3_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="SSF54821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01009">
        <property type="entry name" value="rpsC_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="12">
        <location>
            <begin position="38"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="213"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP43920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY28717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="267" mass="29425" checksum="C1C40AEC0A99870A" modified="2017-04-12" version="1">MGQKINPNGFRLGITTDHTTRWYSDKQYSEFVGEDVKIREYLTKNLERAGVSSIEIERRSERVTIFLHAARPGIVIGRNGAEAERVRAELEKLTGKQVQLNILEVKNPEIDAQLVAQGVAEQLGARVAFRRAMRKAQQTAMRAGAKGIRIKCSGRLGGAEMSRSEGYRDGQVPLHTLRADIDYGFYEARTTFGRIGVKVWIYKGDVAGTRAERAAQKAARASAPGNRQRPGRRPARGEGRGDRPERGGRRRADAAEQAAPATENAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCY3</accession>
    <name>A0A1Q2CCY3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplR</name>
        <name evidence="9" type="ORF">RPIT_03170</name>
        <name evidence="10" type="ORF">SAMN05428934_101235</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03170"/>
    <dbReference type="EnsemblBacteria" id="AQP43940">
        <property type="protein sequence ID" value="AQP43940"/>
        <property type="gene ID" value="RPIT_03170"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29379">
        <property type="protein sequence ID" value="SDY29379"/>
        <property type="gene ID" value="SAMN05428934_101235"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03170"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_B">
        <property type="entry name" value="Ribosomal_L18_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005484">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004389">
        <property type="entry name" value="Ribosomal_L18_bac-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12899">
        <property type="entry name" value="PTHR12899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00861">
        <property type="entry name" value="Ribosomal_L18p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00060">
        <property type="entry name" value="L18_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP43940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY29379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="127" mass="13519" checksum="45213A6A988E17AF" modified="2017-04-12" version="1">MAISLSNSKSLAPKAASKARRQLRGRKKISGSGDRPRLVVTRSSRHLFVQVIDDTQGRTLASASTMEADLRSAEGDKSDKARKVGALIAERAKAAGVEQVVFDRAGNKYHGRIAALADSAREAGLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD05</accession>
    <name>A0A1Q2CD05_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43998">
        <property type="protein sequence ID" value="AQP43998"/>
        <property type="gene ID" value="RPIT_03525"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03525"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="132" mass="13810" checksum="FEAAC462823C1749" modified="2017-04-12" version="1">MSVSLRLQRTVSCLLAWCLPLIGNRLALMVAPAGEGQHVDMFGITSVQFQAALIGTAVGAAAGVAVIVVRKLGWRWLAVAVPLVIAGTWAAGALEETPLVTDGRPIVLAAMLIAPIVAAWVTQPPRGTRHAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD93</accession>
    <name>A0A1Q2CD93_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ATP-binding cassette, subfamily B</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">Protein tyrosine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_03910</name>
        <name evidence="11" type="ORF">SAMN05428934_101386</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY33721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03910"/>
    <dbReference type="EnsemblBacteria" id="AQP44066">
        <property type="protein sequence ID" value="AQP44066"/>
        <property type="gene ID" value="RPIT_03910"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY33721">
        <property type="protein sequence ID" value="SDY33721"/>
        <property type="gene ID" value="SAMN05428934_101386"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03910"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
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    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="31"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="358"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="390"/>
            <end position="397"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY33721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="603" mass="65014" checksum="F732690E49011360" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDB3</accession>
    <name>A0A1Q2CDB3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UvrABC system protein C</fullName>
            <shortName evidence="6">Protein UvrC</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Excinuclease ABC subunit C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">uvrC</name>
        <name evidence="10" type="ORF">RPIT_04175</name>
        <name evidence="11" type="ORF">SAMN05428934_101439</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with UvrB in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UvrC family.</text>
    </comment>
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        <property type="protein sequence ID" value="AQP44108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY35285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04175"/>
    <dbReference type="EnsemblBacteria" id="AQP44108">
        <property type="protein sequence ID" value="AQP44108"/>
        <property type="gene ID" value="RPIT_04175"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY35285">
        <property type="protein sequence ID" value="SDY35285"/>
        <property type="gene ID" value="SAMN05428934_101439"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04175"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00203">
        <property type="entry name" value="UvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041663">
        <property type="entry name" value="DisA/LigA_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004791">
        <property type="entry name" value="UvrC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001162">
        <property type="entry name" value="UvrC_RNase_H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038476">
        <property type="entry name" value="UvrC_RNase_H_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12826">
        <property type="entry name" value="HHH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08459">
        <property type="entry name" value="UvrC_HhH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00194">
        <property type="entry name" value="uvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50165">
        <property type="entry name" value="UVRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0227">DNA damage</keyword>
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    <keyword evidence="5 6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 6" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="GIY-YIG" evidence="8">
        <location>
            <begin position="16"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="7">
        <location>
            <begin position="208"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="UVRC" evidence="9">
        <location>
            <begin position="259"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY35285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="639" mass="70795" checksum="ECF3F58BA5F55B53" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDC5</accession>
    <name>A0A1Q2CDC5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase</fullName>
            <ecNumber evidence="6 7">6.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">D-alanyl-D-alanine-adding enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">murF</name>
        <name evidence="11" type="ORF">RPIT_04010</name>
        <name evidence="12" type="ORF">SAMN05428934_101405</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine</text>
            <dbReference type="Rhea" id="RHEA:28374"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6 7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MurCDEF family. MurF subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.10" evidence="6 7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY34230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04010"/>
    <dbReference type="EnsemblBacteria" id="AQP44080">
        <property type="protein sequence ID" value="AQP44080"/>
        <property type="gene ID" value="RPIT_04010"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY34230">
        <property type="protein sequence ID" value="SDY34230"/>
        <property type="gene ID" value="SAMN05428934_101405"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04010"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047480">
        <property type="term" value="F:UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008766">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02019">
        <property type="entry name" value="MurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005863">
        <property type="entry name" value="UDP-N-AcMur_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01143">
        <property type="entry name" value="murF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 6 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 6 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="8">
        <location>
            <begin position="31"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="10">
        <location>
            <begin position="112"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="9">
        <location>
            <begin position="331"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="114"/>
            <end position="120"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY34230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="477" mass="49244" checksum="D76DFAF76A5FD236" modified="2017-04-12" version="1">MRPRLMSELVDLMQPAPVELFGEDATVGPDVVIDNREATEGCLFVAIPGERVDGHAFAGAAVEAGARGIIGMYSTEADVPHLLAEDSVTALSWLARGLVREARARGMISIGVTGSSGKTSTKDLMAQVFEAAGPTVAPVGSQNNEVGVPLTACRIDDETAYLVSEMGARGIGHISWLTSLVGLDVGVCLNVGRAHVGEFGGVEATAKAKSEIVADLSSEGWAVLNANDPAVAAMRERTSARVAWFGEGDLPPGDLRVSARDVTLNGLSQASFELVVSDDDGDRTARVELSVIGRHQVMNALAAAAAAVAVGLDVESVASSLSGATQRSSWRMELLQRHDGVLVLNDAYNANPDSMEVGLRTAVELGLSTRAEHPSGRVIAVLGDMLELGPLTEESHVELGRLAADMGVAEVIAVGENASSIVAGATAEGLAARVSDRDSIASSLNLSPGDVVLIKGSRGVGLETVAAELVALDGDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDN0</accession>
    <name>A0A1Q2CDN0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GTPase Obg</fullName>
            <ecNumber evidence="6">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">GTP-binding protein Obg</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">obg</name>
        <name evidence="10" type="ORF">RPIT_04675</name>
        <name evidence="11" type="ORF">SAMN05428934_101542</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04675"/>
    <dbReference type="EnsemblBacteria" id="AQP44197">
        <property type="protein sequence ID" value="AQP44197"/>
        <property type="gene ID" value="RPIT_04675"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37900">
        <property type="protein sequence ID" value="SDY37900"/>
        <property type="gene ID" value="SAMN05428934_101542"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04675"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01898">
        <property type="entry name" value="Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01454">
        <property type="entry name" value="GTPase_Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014100">
        <property type="entry name" value="GTP-bd_Obg/CgtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036346">
        <property type="entry name" value="GTP-bd_prot_GTP1/OBG_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015349">
        <property type="entry name" value="OCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="PTHR11702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09269">
        <property type="entry name" value="DUF1967"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102741">
        <property type="entry name" value="SSF102741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="SSF82051"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02729">
        <property type="entry name" value="Obg_CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03595">
        <property type="entry name" value="Obg_CgtA_exten"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51881">
        <property type="entry name" value="OCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Obg" evidence="9">
        <location>
            <begin position="4"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="7">
        <location>
            <begin position="163"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="OCT" evidence="8">
        <location>
            <begin position="355"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="169"/>
            <end position="176"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="194"/>
            <end position="198"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="215"/>
            <end position="218"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
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        <location>
            <begin position="285"/>
            <end position="288"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="314"/>
            <end position="316"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00007699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01454"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51883"/>
        </source>
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        <source>
            <dbReference type="EMBL" id="AQP44197.1"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY37900.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="496" mass="52489" checksum="B7D1385B4E2EA6FE" modified="2017-04-12" version="1">MAIPSFVDRVKLTVEAGNGGHGCASVHREKFKPLGGPDGGNGGDGGSIIFRVDDSLSTLVEYHRQSVRRAVNGQPGRGDHQHGARGQDVVLAVPSGTIISDADTGEVLADLTEIGAEFIAAEGGKGGLGNAALASASRKAPGFALLGEEGQSRAVQLELKVVADVGLVGFPSAGKSSLIAAISRARPKIADYPFTTLVPNLGVVVAGDVTYTVADVPGLIEGASEGRGLGFDFLRHIERCQAIVHVIDLGTYEPGRDPISDLEVIEAELAAHGGLEDRVRMIALNKIDLPDAPDLADIALPELKKFGHRIFRISTKTGEGLPELKFAMAEVVAARRAALPAAAAPKKVLRPSPVASKGSQEEFTIVKKGDGEGGFVWRVRGAKPERWIRQTDFNNAEAVGYLADRLNRLGVEDKLLEIGARPGDAVAIGGEDAVVFDFAPQVDVGAEILSRRGEDTRLEEQRPAVTRRRRMDAEYHAAKAVDYATGGYQPEADDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDN3</accession>
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        </submittedName>
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
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            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
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        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="protein sequence ID" value="SDY39050"/>
        <property type="gene ID" value="SAMN05428934_101587"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        </location>
    </feature>
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            <begin position="38"/>
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        </location>
        <ligand>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
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    </evidence>
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            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44232.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY39050.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="236" mass="25915" checksum="A70020A79E8B083C" modified="2017-04-12" version="1">MTAPAITIRHLSKSYGALPALQDLNLTLRGGQIVGLLGENGCGKTTLLKVIAGALSQWRGDVEIHGHRPGPESKAIVSFLPDASFLADGDTIDDCIAQYRDFFADFQESKCRDLVRFFGLDTGRKLATLSKGMREKAQIALAMSRDAKVFLLDEPISGVDPAARDVLLEAIVRDLPEDALVLISTHLIHDLEPVLDAVAFMRFGTILLSGEVDDLREQHGNSIDQLFREVYKWSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDQ3</accession>
    <name>A0A1Q2CDQ3_9ACTN</name>
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        <recommendedName>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the HrcA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY39365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04965"/>
    <dbReference type="EnsemblBacteria" id="AQP44244">
        <property type="protein sequence ID" value="AQP44244"/>
        <property type="gene ID" value="RPIT_04965"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY39365">
        <property type="protein sequence ID" value="SDY39365"/>
        <property type="gene ID" value="SAMN05428934_101599"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04965"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00081">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002571">
        <property type="entry name" value="HrcA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021153">
        <property type="entry name" value="HrcA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023120">
        <property type="entry name" value="WHTH_transcript_rep_HrcA_IDD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34824">
        <property type="entry name" value="PTHR34824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01628">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005485">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00331">
        <property type="entry name" value="hrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0678">Repressor</keyword>
    <keyword evidence="3 5" id="KW-0346">Stress response</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="7">
        <location>
            <begin position="16"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="HrcA" evidence="6">
        <location>
            <begin position="103"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY39365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="334" mass="35663" checksum="E8451265709367F7" modified="2017-04-12" version="1">MLDDRKLEVLKAIVTDYVSSREPVGSKALVERHKLDVSAATVRNDMAALEEEGYIMQPHTSAGRIPTDKGYRLFVDRLAQIKPLSSAERTAITSFMNGTADVDDLVTRTVRLLAQLTRQVAIVQYPVAQRSTIRHVEFILLTPDRVLVIVVQSSGRVDQATLEVPVTDESELHALRSKVLAAVIGKTPADAASALASLLEGVAPDARSFAGPVVAGLLEAIAAEPAAHVLVAGVPNLASGPFFEANLRPLLEALEEQVVLMRLLGEAAGDDVTVRIGQENTDEPFQATSLIASGYGADFSASLGVLGPTRMDYPSTIAAVRAVARYVSRFLTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDU4</accession>
    <name>A0A1Q2CDU4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">6-phosphofructokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_05260</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11 12">RP1T</strain>
        </source>
    </reference>
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        <reaction evidence="1">
            <text>ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="AQP44294">
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        <property type="gene ID" value="RPIT_05260"/>
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        <property type="reaction ID" value="UER00182"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:6-phosphofructokinase activity"/>
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        <property type="project" value="UniProtKB-EC"/>
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        <location>
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            <end position="309"/>
        </location>
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        <location>
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            <end position="672"/>
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00000432"/>
        </source>
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    <evidence type="ECO:0000256" key="2">
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            <dbReference type="ARBA" id="ARBA00001946"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
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            <dbReference type="EMBL" id="AQP44294.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="736" mass="78716" checksum="6A2AFE786E717C64" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 4" key="2">
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">RP1</strain>
        </source>
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    <reference evidence="1" key="3">
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            </authorList>
        </citation>
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            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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            <dbReference type="EMBL" id="AQP44322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="313" mass="33474" checksum="CF541A2D51B5BFAA" modified="2017-04-12" version="1">MSERIATEVDGVQLSLSNLDQPLFPNGFTKGELISYYLEIAEVMLPHLSDRAITRVRFPDGAGAPSFYEKNAPAGTPEWVRTVDVATSSGPISYVTARQRADLVWLANLRAIELHTPQWRFVDATQGDGGVILDGPDEPRATTLIIDLDPGPGITPEDSARGAIIAATTLAELGLEAFPKTSGNKGLQLSVPIQPTPASEVYSFAQALARHLTAAHPKLFVATMSKDARGGLIFVDFAQNYAARNTVTAYSVRGLDTPSVATPLTWDEVAALQPDSTLRTSPAKVMARVQDLGDLWQAQEPTSSSPSLPAPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDW9</accession>
    <name>A0A1Q2CDW9_9ACTN</name>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
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            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY40143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="120" mass="13339" checksum="1DCF53D614442743" modified="2017-04-12" version="1">MSQGRIADPLDPTESRQAFVSVAETPQYLKLRSSFRNFAFPMTLAGLVSYFTFVLLSVFAEDFMAQPFLGMAGLNTGLMIGFLQFAIVWIWTAIYVNYANTRLDPISAEIKDELVAKGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDX9</accession>
    <name>A0A1Q2CDX9_9ACTN</name>
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        <submittedName>
            <fullName evidence="3">Dipeptidyl aminopeptidase/acylaminoacyl peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05185</name>
        <name evidence="3" type="ORF">SAMN05428934_101643</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY40517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44280">
        <property type="protein sequence ID" value="AQP44280"/>
        <property type="gene ID" value="RPIT_05185"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY40517">
        <property type="protein sequence ID" value="SDY40517"/>
        <property type="gene ID" value="SAMN05428934_101643"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05185"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9" evidence="1">
        <location>
            <begin position="386"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY40517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="606" mass="65365" checksum="665B18FA7B3DA5BD" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE62</accession>
    <name>A0A1Q2CE62_9ACTN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05805</name>
        <name evidence="3" type="ORF">SAMN05428934_103108</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP44387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44387">
        <property type="protein sequence ID" value="AQP44387"/>
        <property type="gene ID" value="RPIT_05805"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67911">
        <property type="protein sequence ID" value="SDY67911"/>
        <property type="gene ID" value="SAMN05428934_103108"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05805"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY67911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="66" mass="7097" checksum="1827BBF5CEC1DFA9" modified="2017-04-12" version="1">MSDLFPINAGVTEQNLVEEVTGRTPQVEDDHAPDTREPGDPVESPGPDDEIQVGGRVEGEDPRDNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEB0</accession>
    <name>A0A1Q2CEB0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">CopG family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_05930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05930"/>
    <dbReference type="EnsemblBacteria" id="AQP44410">
        <property type="protein sequence ID" value="AQP44410"/>
        <property type="gene ID" value="RPIT_05930"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05930"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="67" mass="7363" checksum="F0BDD0E6D6E2DFFC" modified="2017-04-12" version="1">MAMTLRLSEEDERALAALAEAQGVSRQEATVRAIHEAAERRGHEARMTGASARARARYADLLDRLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEF0</accession>
    <name>A0A1Q2CEF0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_06480</name>
        <name evidence="2" type="ORF">SAMN05428934_103241</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY71352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06480"/>
    <dbReference type="EnsemblBacteria" id="AQP44499">
        <property type="protein sequence ID" value="AQP44499"/>
        <property type="gene ID" value="RPIT_06480"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71352">
        <property type="protein sequence ID" value="SDY71352"/>
        <property type="gene ID" value="SAMN05428934_103241"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06480"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY71352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="157" mass="16864" checksum="67B3A5BD7C31C80B" modified="2017-04-12" version="1">MNDYAADAPLDADDERLLAAVASAQLEHDPVPDGLIDRLMFAVSLEIMEAELATLESRDLATVRSIDPVVVDTITFTASTTSFMVSLSESDGGVRIDGWVTGGGVEVELRAGALRLSRVSDATGRLTWEHVPHGPVRFLIQPSRPGQRPVVTPTIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEH1</accession>
    <name>A0A1Q2CEH1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">1,4-alpha-glucan branching enzyme GlgB</fullName>
            <ecNumber evidence="9">2.4.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Alpha-(1-&gt;4)-glucan branching enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Glycogen branching enzyme</fullName>
            <shortName evidence="9">BE</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">glgB</name>
        <name evidence="12" type="ORF">RPIT_06560</name>
        <name evidence="13" type="ORF">SAMN05428934_103257</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.</text>
            <dbReference type="EC" id="2.4.1.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.18" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06560"/>
    <dbReference type="EnsemblBacteria" id="AQP44514">
        <property type="protein sequence ID" value="AQP44514"/>
        <property type="gene ID" value="RPIT_06560"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71796">
        <property type="protein sequence ID" value="SDY71796"/>
        <property type="gene ID" value="SAMN05428934_103257"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06560"/>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102752">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02855">
        <property type="entry name" value="E_set_GBE_prok_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00685">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037439">
        <property type="entry name" value="Branching_enzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006407">
        <property type="entry name" value="GlgB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044143">
        <property type="entry name" value="GlgB_N_E_set_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43651">
        <property type="entry name" value="PTHR43651"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000463">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01515">
        <property type="entry name" value="branching_enzym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 9" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="4 9" id="KW-0321">Glycogen metabolism</keyword>
    <keyword evidence="5 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aamy" evidence="11">
        <location>
            <begin position="147"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9 10">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9 10">
        <location>
            <position position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000463-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP44514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY71796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="631" mass="72535" checksum="47A6F0C9AE21EDDA" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEH7</accession>
    <name>A0A1Q2CEH7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA-specific 2-thiouridylase MnmA</fullName>
            <ecNumber evidence="7">2.8.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mnmA</name>
        <name evidence="8" type="ORF">RPIT_06530</name>
        <name evidence="9" type="ORF">SAMN05428934_103251</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] + uridine(34) in tRNA = 2-thiouridine(34) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:47032"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11726"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="Rhea" id="RHEA-COMP:11728"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:87170"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.8.1.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MnmA/TRMU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.13" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06530"/>
    <dbReference type="EnsemblBacteria" id="AQP44508">
        <property type="protein sequence ID" value="AQP44508"/>
        <property type="gene ID" value="RPIT_06530"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71638">
        <property type="protein sequence ID" value="SDY71638"/>
        <property type="gene ID" value="SAMN05428934_103251"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06530"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01998">
        <property type="entry name" value="tRNA_Me_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00144">
        <property type="entry name" value="tRNA_thiouridyl_MnmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023382">
        <property type="entry name" value="Adenine_a_hdrlase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004506">
        <property type="entry name" value="tRNA-specific_2-thiouridylase"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00420">
        <property type="entry name" value="trmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Interaction with tRNA" evidence="7">
        <location>
            <begin position="148"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="7">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="6"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="7">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="7">
        <location>
            <position position="337"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Alternate" evidence="7">
        <location>
            <begin position="101"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY71638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="358" mass="38722" checksum="2C1E479AF5BEBD08" modified="2017-04-12" version="1">MRVLVAMSGGVDSAVAAARLVAEGHDVTGVHLALSRNPASYRSGARGCCSLEDSHDARRVADKLDIPFYVWDFAEEFHEAVVEDFVAEYRAGRTPNPCLRCNEKIKFAAVLDRGVRLGFDAVATGHYADLRHHDDSSVTLHRAADAAKDQSYVLGMLNQDQLRRCLFPLHDVEKPVVREEANVLGFGVARKPDSHDICFIADGDTQGFLGRYIDERPGSIVDAAGQVLGEHLGTHRYTVGQRRGLDLRVPAPTGEPRYVLSIEPVSNTVVVGGREDLAVGELGCIRATWTGEPVAGRWRGEAQFRAHGIPQPASFEAVGDGLRVTFDEPASGVAPGQTVVAYDDDRVVGSAVIAETSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEJ9</accession>
    <name>A0A1Q2CEJ9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_06755</name>
        <name evidence="2" type="ORF">SAMN05428934_11096</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44552">
        <property type="protein sequence ID" value="AQP44552"/>
        <property type="gene ID" value="RPIT_06755"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09951">
        <property type="protein sequence ID" value="SDZ09951"/>
        <property type="gene ID" value="SAMN05428934_11096"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06755"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ09951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="165" mass="17679" checksum="7D8C38D7384483BB" modified="2017-04-12" version="1">MRSFLAVVCGVALLTGCVDRPEPAPAIQRETAAPWDAPRDAISYIQGGGFPELSLGDDTDPWVLSLDVTVDGEAVDIPAYIGVDRLRAVQAPVHTHEPGGDVWLEGDGNRDITLGDFFYLWGVRFTDECLGATCGDLRVEADGEQVVNPTSLILRGHETVTVSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEK5</accession>
    <name>A0A1Q2CEK5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP synthase subunit alpha</fullName>
            <ecNumber evidence="10">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">ATP synthase F1 sector subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">F-ATPase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">atpA</name>
        <name evidence="14" type="ORF">RPIT_06675</name>
        <name evidence="15" type="ORF">SAMN05428934_110112</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1T</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1</strain>
        </source>
    </reference>
    <reference evidence="14" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="10"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ10248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06675"/>
    <dbReference type="EnsemblBacteria" id="AQP44536">
        <property type="protein sequence ID" value="AQP44536"/>
        <property type="gene ID" value="RPIT_06675"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ10248">
        <property type="protein sequence ID" value="SDZ10248"/>
        <property type="gene ID" value="SAMN05428934_110112"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06675"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18113">
        <property type="entry name" value="ATP-synt_F1_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01132">
        <property type="entry name" value="F1_ATPase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01346">
        <property type="entry name" value="ATP_synth_alpha_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000793">
        <property type="entry name" value="ATP_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038376">
        <property type="entry name" value="ATP_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033732">
        <property type="entry name" value="ATP_synth_F1_a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00306">
        <property type="entry name" value="ATP-synt_ab_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00962">
        <property type="entry name" value="atpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0139">CF(1)</keyword>
    <keyword evidence="10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_ab_N" evidence="13">
        <location>
            <begin position="31"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab" evidence="11">
        <location>
            <begin position="154"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab_C" evidence="12">
        <location>
            <begin position="384"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="174"/>
            <end position="181"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Required for activity" evidence="10">
        <location>
            <position position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="AQP44536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="SDZ10248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="545" mass="59168" checksum="EAD9BA1DF79F6054" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEP3</accession>
    <name>A0A1Q2CEP3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted Zn-dependent peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_06885</name>
        <name evidence="4" type="ORF">SAMN05428934_11069</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06885"/>
    <dbReference type="EnsemblBacteria" id="AQP44571">
        <property type="protein sequence ID" value="AQP44571"/>
        <property type="gene ID" value="RPIT_06885"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09504">
        <property type="protein sequence ID" value="SDZ09504"/>
        <property type="gene ID" value="SAMN05428934_11069"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06885"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M16" evidence="1">
        <location>
            <begin position="21"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="2">
        <location>
            <begin position="177"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ09504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="424" mass="46245" checksum="CE0399DA0D77F001" modified="2017-04-12" version="1">MSEAELNYELVVDTLPNGLQVAVSPDPAAPGVAVNLWVAVGSADEEPGRTGFAHLFEHLMFQGSAAVASGEHMATIEGLGGTVNATTSSDRTNYFETVPRSALDLALWLEADRLASLAITPENFEAQRQVVKEEKRQRYDNQPYGDLLELLTAQHFDPAHPYGHLTIGSMADLDAASLDDVAGFFERWYRPSNIRLVLCGPVTPDEGLELARRRLGHLPKLSAPSRATMPVVSGPEPHTTSVTRAVPHSLAYLSWRTPPAHHPDHLALDLALAILSDGHASRLHRSLVKRRDVANEVHSATLTNRSASSIATVLGRPSDDVPIPALADAILAELAAFIDGGPREEELARAVAQYERDWLWELATTTGRADAINESWLLHGDPQRVNTHLAEIVALSCDDVRRAAGRWLSPDDAYQLHYHAEDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CES6</accession>
    <name>A0A1Q2CES6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07090"/>
    <dbReference type="EnsemblBacteria" id="AQP44608">
        <property type="protein sequence ID" value="AQP44608"/>
        <property type="gene ID" value="RPIT_07090"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07090"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021408">
        <property type="entry name" value="DUF3046"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11248">
        <property type="entry name" value="DUF3046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="64" mass="7263" checksum="DED9C2E65EC9FDC2" modified="2017-04-12" version="1">MREVELWARMAAVLPGGYAATWADQVVLEDLDGRTVRDALGAGIPCKRIWRAVWRQLELPDTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEX3</accession>
    <name>A0A1Q2CEX3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rifampin ADP-ribosyl transferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Rifampin ADP-ribosylating transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_07500</name>
        <name evidence="4" type="ORF">SAMN05428934_1195</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000019">
        <property type="protein sequence ID" value="SDZ21856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44672">
        <property type="protein sequence ID" value="AQP44672"/>
        <property type="gene ID" value="RPIT_07500"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ21856">
        <property type="protein sequence ID" value="SDZ21856"/>
        <property type="gene ID" value="SAMN05428934_1195"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07500"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038611">
        <property type="entry name" value="Arr_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021975">
        <property type="entry name" value="Rifampin_Arr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12120">
        <property type="entry name" value="Arr-ms"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Arr-ms" evidence="2">
        <location>
            <begin position="190"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ21856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="316" mass="33584" checksum="0B1B996E63E4B277" modified="2017-04-12" version="1">MTSVGDFALTMDELRAVTEYTVACAVPVLGLFEQAAPDDDRPASALKAAQEFVDGEARSKRLRTSATEAHRAGREAPTQAAAHAATAAGDAAASAFLHPLANGTQVRHILGAATHAARAAELSRGDDPVVAEYMLHAAARRMTPTVRGVLGRYPRAPRGNTRHAALMQQLDSLIRDPAPQPQPADDTGPFFHGTRADLRPGELLTPGWGTNYGSGKKSQHIYLTASEQGAPLAAAIALGDGAPRVYRVEPLGPIYDDPNVTDKKFPGNPTRSYRTTEPLRVMEEIIGFTLPDPGVVERIRASAAELKALGIEAMDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF44</accession>
    <name>A0A1Q2CF44_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">3-isopropylmalate dehydratase large subunit</fullName>
            <ecNumber evidence="14">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Alpha-IPM isomerase</fullName>
            <shortName evidence="14">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">leuC</name>
        <name evidence="17" type="ORF">RPIT_07905</name>
        <name evidence="18" type="ORF">SAMN05428934_11321</name>
    </gene>
    <organism evidence="17 19">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 19" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">RP1T</strain>
        </source>
    </reference>
    <reference evidence="18 20" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">RP1</strain>
        </source>
    </reference>
    <reference evidence="17" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 14">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 14">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = 2-methyl-cis-aconitate + H2O</text>
            <dbReference type="Rhea" id="RHEA:17941"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="ChEBI" id="CHEBI:57872"/>
            <dbReference type="EC" id="4.2.1.99"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="14">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 14">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Organic acid metabolism; propanoate degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="14"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07905"/>
    <dbReference type="EnsemblBacteria" id="AQP44739">
        <property type="protein sequence ID" value="AQP44739"/>
        <property type="gene ID" value="RPIT_07905"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16414">
        <property type="protein sequence ID" value="SDZ16414"/>
        <property type="gene ID" value="SAMN05428934_11321"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07905"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00946"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047456">
        <property type="term" value="F:2-methylisocitrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01583">
        <property type="entry name" value="IPMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01026">
        <property type="entry name" value="LeuC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004430">
        <property type="entry name" value="3-IsopropMal_deHydase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033941">
        <property type="entry name" value="IPMI_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00170">
        <property type="entry name" value="leuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8 14" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13 14" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="10 14" id="KW-0408">Iron</keyword>
    <keyword evidence="11 14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 14" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="9 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="16">
        <location>
            <begin position="7"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="420"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="421"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="410"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="AQP44739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="SDZ16414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="468" mass="49965" checksum="395936534A334F8C" modified="2017-04-12" version="1">MGKTLSEKVWDAHVVRSVEGEPDLLYIDLHLVHEVTSPQAFEGLRLAGRQVRRPELTLATEDHNTPTLNILAPIADPVSRKQVDTLRQNAKDFGIRIHSLGDRDQGVVHIIGPQLGVTQPGMTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLNQAKPKTMAVNINGDLPDGVTAKDVVLALIAKVGTGGGQGHIVEYRGTTIEQLSMEGRMTICNMSIEWGAKAGMIAPDETTFAYLKGRPHAPEGEDWDAAVEYWRTLKTDDDATFDVEVDIDATQLTPFVTWGTNPGHGVPLGAAVPAPEDFDSEVEQATARRALEYMDLVPGTPMRDIKVDTVFLGSCTNGRIEDLRLAASVLQGQRIADGVRMLVVPGSARVRLQAETEGLDQVFLDFGAEWRAAGCSMCLGMNPDQLAPGERAASTSNRNFEGRQGKGGRTHLVSPAVAAATAIVGHLAAPADLIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF47</accession>
    <name>A0A1Q2CF47_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ca-activated chloride channel family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_07865</name>
        <name evidence="6" type="ORF">SAMN05428934_11313</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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    <sequence length="667" mass="69797" checksum="F6824A13D1CDBF6F" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
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            <dbReference type="PubMed" id="26869509"/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="329" mass="35259" checksum="7B170AB59BE325A3" modified="2017-04-12" version="1">MRALAADYDAALFDLDGVIYLGPVAVEGIPEAVDELRSRGTRLGFVTNNAARTPAAVAAHLVELGIHAGGADVVNSTQATLRMLADDLPAGATVLAVGTAALAEQLTEAGFTVVGSLDDEPVAVVQGYHPTIEWQRLEEAALAVQRGAAWYATNPDLTRPSDRGIVPGLGSQLAVVRVCVDVEPKIAGKPFRPLLDETVLRLGSERPIFVGDRTDTDILGANNVQMDSLFVFTGAHGKLDLAEAAPEYRPTYIGYDASALLEPPREAEFQSQRIVCGYQEVDLSNGCGYLSTRPVTRDEQLDALWAALQARWRYDCDISAVLNSLDTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Schumann P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">RP1T</strain>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    </dbReference>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY97029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="250" mass="25393" checksum="09D539E090F4EE60" modified="2017-04-12" version="1">MTAAISAEQRKYFSTSGWIIGLLCLLAFGMVMPVGNAISVNANTQGTVSNVAGLGGVADFGLMVLMVIAATSVTQEYRFGTANASFLGLPGRVHWLAAKATLMAVIAALSATVLAVLGVVAVSLIAAPYKQDGVSLVAALPQIGMAALTSAVMAVLAVGVGALVRSTAFAVALIVLWPTVVELLLAKLPGLSEHTPKFLLWANAGYAMTGRDMGTEFLWGPGGAVAYLAVIAAVVFVAGAVVTKSVTPSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFH3</accession>
    <name>A0A1Q2CFH3_9ACTN</name>
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        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L35</fullName>
        </recommendedName>
    </protein>
    <gene>
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        <name evidence="8" type="ORF">SAMN05428934_11520</name>
    </gene>
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    </organism>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL35 family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ19411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08275"/>
    <dbReference type="EnsemblBacteria" id="AQP44795">
        <property type="protein sequence ID" value="AQP44795"/>
        <property type="gene ID" value="RPIT_08275"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19411">
        <property type="protein sequence ID" value="SDZ19411"/>
        <property type="gene ID" value="SAMN05428934_11520"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00514">
        <property type="entry name" value="Ribosomal_L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021137">
        <property type="entry name" value="Ribosomal_L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018265">
        <property type="entry name" value="Ribosomal_L35_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001706">
        <property type="entry name" value="Ribosomal_L35_non-mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037229">
        <property type="entry name" value="Ribosomal_L35_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33343">
        <property type="entry name" value="PTHR33343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01632">
        <property type="entry name" value="Ribosomal_L35p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00064">
        <property type="entry name" value="RIBOSOMALL35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143034">
        <property type="entry name" value="SSF143034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00001">
        <property type="entry name" value="rpmI_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00936">
        <property type="entry name" value="RIBOSOMAL_L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ19411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="68" mass="7586" checksum="D6304F5DBF29AF45" modified="2017-04-12" version="1">MPKMKSHSGAKKRFKTTGTGKLLRRQANLGHLNEHKSSVRTRRLSSPESVAPADAKKVRKLLGKHKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFH6</accession>
    <name>A0A1Q2CFH6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">B12-binding domain-containing radical SAM protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Radical SAM family uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08760</name>
        <name evidence="3" type="ORF">SAMN05428934_10762</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08760"/>
    <dbReference type="EnsemblBacteria" id="AQP44869">
        <property type="protein sequence ID" value="AQP44869"/>
        <property type="gene ID" value="RPIT_08760"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97556">
        <property type="protein sequence ID" value="SDY97556"/>
        <property type="gene ID" value="SAMN05428934_10762"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08760"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023862">
        <property type="entry name" value="CHP03960_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045784">
        <property type="entry name" value="Radical_SAM_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19864">
        <property type="entry name" value="Radical_SAM_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03960">
        <property type="entry name" value="rSAM_fuse_unch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Radical SAM core" evidence="1">
        <location>
            <begin position="266"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY97556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="651" mass="73049" checksum="F0A3B06E9DE3B80C" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFK1</accession>
    <name>A0A1Q2CFK1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dihydroorotase</fullName>
            <shortName evidence="5">DHOase</shortName>
            <ecNumber evidence="5">3.5.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pyrC</name>
        <name evidence="8" type="ORF">RPIT_08950</name>
        <name evidence="9" type="ORF">SAMN05428934_107103</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(S)-dihydroorotate + H2O = H(+) + N-carbamoyl-L-aspartate</text>
            <dbReference type="Rhea" id="RHEA:24296"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="EC" id="3.5.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.3" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08950"/>
    <dbReference type="EnsemblBacteria" id="AQP44902">
        <property type="protein sequence ID" value="AQP44902"/>
        <property type="gene ID" value="RPIT_08950"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98308">
        <property type="protein sequence ID" value="SDY98308"/>
        <property type="gene ID" value="SAMN05428934_107103"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08950"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00117"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004151">
        <property type="term" value="F:dihydroorotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01317">
        <property type="entry name" value="DHOase_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00220_B">
        <property type="entry name" value="PyrC_classI_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004722">
        <property type="entry name" value="DHOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00482">
        <property type="entry name" value="DIHYDROOROTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00483">
        <property type="entry name" value="DIHYDROOROTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="7">
        <location>
            <begin position="43"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="54"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="318"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY98308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="421" mass="44648" checksum="8F173F5CDA9A7B9C" modified="2017-04-12" version="1">MTATVLRAVTLPDGSRTDLKLSDGLIVDDVPAGAEVIDCDGLIALPGLVDVHVHLREPGREDTETVATGVQAAARGGFTAVCAMANTQPVTDTAEKAEHIHDLGLDARDADVAVIGAISKGLRGEELAELGLMHRSRAGVTMFSDDGHCLMNAQLMRRALEWVKPFGGVVAQHSQDSNLAGPGACCHEGELSGRLGLGGWPPVAEAAIIARDAMLAEATGSRLHVCHISTAEGVDVVRWAKARGIQITAEATPHHLLLGTEELVGYDTVYKVNPPLRTSEHIEAVRAALADGTIDVVATDHAPHATQDKDHAFVDARPGMLGLEQALSVVIETMVKTGRLDWSGVADRMSHAPARIARLSGHGQPLAVGSPGNVTLVDPERTAVVDREASRSLSRNNPYHGRDLPDPVEATFLRGRQTFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFK4</accession>
    <name>A0A1Q2CFK4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_08485</name>
        <name evidence="2" type="ORF">SAMN05428934_1078</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY96312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08485"/>
    <dbReference type="EnsemblBacteria" id="AQP44825">
        <property type="protein sequence ID" value="AQP44825"/>
        <property type="gene ID" value="RPIT_08485"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY96312">
        <property type="protein sequence ID" value="SDY96312"/>
        <property type="gene ID" value="SAMN05428934_1078"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08485"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY96312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="1127" mass="124191" checksum="156F8F121154175B" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFN5</accession>
    <name>A0A1Q2CFN5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">L-arabinose isomerase</fullName>
            <ecNumber evidence="6">5.3.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">araA</name>
        <name evidence="8" type="ORF">RPIT_08975</name>
        <name evidence="9" type="ORF">SAMN05428934_107108</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the conversion of L-arabinose to L-ribulose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>beta-L-arabinopyranose = L-ribulose</text>
            <dbReference type="Rhea" id="RHEA:14821"/>
            <dbReference type="ChEBI" id="CHEBI:16880"/>
            <dbReference type="ChEBI" id="CHEBI:40886"/>
            <dbReference type="EC" id="5.3.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Binds 1 Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the arabinose isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.4" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08975"/>
    <dbReference type="EnsemblBacteria" id="AQP44907">
        <property type="protein sequence ID" value="AQP44907"/>
        <property type="gene ID" value="RPIT_08975"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98408">
        <property type="protein sequence ID" value="SDY98408"/>
        <property type="gene ID" value="SAMN05428934_107108"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08975"/>
    <dbReference type="UniPathway" id="UPA00145">
        <property type="reaction ID" value="UER00565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008733">
        <property type="term" value="F:L-arabinose isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019569">
        <property type="term" value="P:L-arabinose catabolic process to xylulose 5-phosphate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00519">
        <property type="entry name" value="Arabinose_Isome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024664">
        <property type="entry name" value="Ara_Isoase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038583">
        <property type="entry name" value="AraA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004216">
        <property type="entry name" value="Fuc/Ara_isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009015">
        <property type="entry name" value="Fucose_isomerase_N/cen_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003762">
        <property type="entry name" value="Lara_isomerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38464">
        <property type="entry name" value="PTHR38464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11762">
        <property type="entry name" value="Arabinose_Iso_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02610">
        <property type="entry name" value="Arabinose_Isome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001478">
        <property type="entry name" value="L-ara_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50443">
        <property type="entry name" value="SSF50443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53743">
        <property type="entry name" value="SSF53743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0054">Arabinose catabolism</keyword>
    <keyword evidence="5 6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 6 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 6" id="KW-0464">Manganese</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arabinose_Iso_C" evidence="7">
        <location>
            <begin position="363"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="351"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="450"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY98408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="502" mass="55300" checksum="30AAF83E3C7EA117" modified="2017-04-12" version="1">MKNPFDGKEIWFLTGSQDLYGPETLEQVAEQAKEVVSHLDGAEAIPVKISWRPTLKDRDAIRDEMLAANADPNCIGVITWMHTFSPAKMWILGLAALDKPMLHLHTQASMELPWATIDMDYMNLNQSAHGDREFAYIASRLGKARRTVVGHASTPQVHEKIGTWARAAAGWDALHHLTLARFGDNMRYVAVTEGDKTEAELKLGVAVNTWGVNELVEAVEAVEESAIDQLAAEYEELYDVAAELRKGGERHESLRYGARQELGLRSFLESGDFGAFTTNFQDLGALKQLPGLAVQRLMADGYGFGAEGDWKTAILVRVAKIMGYGLPGGASLMEDYVYEMTPGNEKILGAHMLEVCPSLTTAKPKLEIHPLGIGGKEDPVRLVFTADSGPALVIAMSDMRERFRLIMNIVENVEPDAPLPKLPVARAVWVPEPDFATSAECWLTAGAAHHTVMTTATTREMWEDLAEMAAMELAVIDADTTARGFARNLRLEHVWHRATQGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFN6</accession>
    <name>A0A1Q2CFN6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative hydrolase of the HAD superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_09085</name>
        <name evidence="2" type="ORF">SAMN05428934_107130</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44924">
        <property type="protein sequence ID" value="AQP44924"/>
        <property type="gene ID" value="RPIT_09085"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98834">
        <property type="protein sequence ID" value="SDY98834"/>
        <property type="gene ID" value="SAMN05428934_107130"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09085"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY98834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="251" mass="27523" checksum="2EEE35BB149206FB" modified="2017-04-12" version="1">MSDFLISIAVWQTLLDESIEFHGHVRDNRIECVIEAVRERGGHTVSHSDARRALDLAAHEFEEAYLAGSPIDNKERVRIVGDALSVSLSHTEMDSLAQRLGATHQAHSLVPMPGARDALRRLAANYRVVVVSDTWLSPGQTLRAALDYHRMSEFLEDMYFSDETGVSKTSGSAWKYVADRMNIGVSRIIHIGDLPAVDGYIAMKSHCATSIVVPHPSHPIVGSSSSMVGLQAASRLVDVPDLVAKFTGRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFS3</accession>
    <name>A0A1Q2CFS3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribose 5-phosphate isomerase B</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Ribose-5-phosphate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_08915</name>
        <name evidence="5" type="ORF">SAMN05428934_10796</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LacAB/RpiB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08915"/>
    <dbReference type="EnsemblBacteria" id="AQP44895">
        <property type="protein sequence ID" value="AQP44895"/>
        <property type="gene ID" value="RPIT_08915"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98188">
        <property type="protein sequence ID" value="SDY98188"/>
        <property type="gene ID" value="SAMN05428934_10796"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08915"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016861">
        <property type="term" value="F:intramolecular oxidoreductase activity, interconverting aldoses and ketoses"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011860">
        <property type="entry name" value="Rib-5-P_Isoase_Actino"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003500">
        <property type="entry name" value="RpiB_LacA_LacB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036569">
        <property type="entry name" value="RpiB_LacA_LacB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30345">
        <property type="entry name" value="PTHR30345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02502">
        <property type="entry name" value="LacAB_rpiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005384">
        <property type="entry name" value="RpiB_LacA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89623">
        <property type="entry name" value="SSF89623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02133">
        <property type="entry name" value="RPI_actino"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00689">
        <property type="entry name" value="rpiB_lacA_lacB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="D-ribulose 5-phosphate binding" evidence="3">
        <location>
            <begin position="8"/>
            <end position="9"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribulose 5-phosphate binding" evidence="3">
        <location>
            <begin position="67"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR005384-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY98188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="148" mass="16084" checksum="1FE8B002BA41834B" modified="2017-04-12" version="1">MRVHIATDHAGYELKNYLVDRLREAGHDVVDHGAHSYDAQDDYPPLIIPAAEAVVAEPGSLGIVLGGSGNGEQIAANKVRGIRAALATNVDLAKLAREHNDANVISLGGRMQSLEESYAIVEAFLETPFSGEERHQRRIDLLAEYEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFU8</accession>
    <name>A0A1Q2CFU8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 5">Thymidylate synthase</fullName>
            <shortName evidence="5">TS</shortName>
            <shortName evidence="5">TSase</shortName>
            <ecNumber evidence="1 5">2.1.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">thyA</name>
        <name evidence="8" type="ORF">RPIT_09490</name>
        <name evidence="9" type="ORF">SAMN05428934_102408</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dUMP = 7,8-dihydrofolate + dTMP</text>
            <dbReference type="Rhea" id="RHEA:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="2.1.1.45"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.45" evidence="1 5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY59952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09490"/>
    <dbReference type="EnsemblBacteria" id="AQP44988">
        <property type="protein sequence ID" value="AQP44988"/>
        <property type="gene ID" value="RPIT_09490"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59952">
        <property type="protein sequence ID" value="SDY59952"/>
        <property type="gene ID" value="SAMN05428934_102408"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09490"/>
    <dbReference type="UniPathway" id="UPA00575"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004799">
        <property type="term" value="F:thymidylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006231">
        <property type="term" value="P:dTMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00351">
        <property type="entry name" value="TS_Pyrimidine_HMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.572.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00008">
        <property type="entry name" value="Thymidy_synth_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045097">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023451">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036926">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000398">
        <property type="entry name" value="Thymidylate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020940">
        <property type="entry name" value="Thymidylate_synthase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548">
        <property type="entry name" value="PTHR11548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00303">
        <property type="entry name" value="Thymidylat_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00108">
        <property type="entry name" value="THYMDSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55831">
        <property type="entry name" value="SSF55831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03284">
        <property type="entry name" value="thym_sym"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00091">
        <property type="entry name" value="THYMIDYLATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4 5" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylat_synt" evidence="7">
        <location>
            <begin position="2"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="126"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="172"/>
            <end position="175"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="213"/>
            <end position="215"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY59952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="270" mass="30272" checksum="062B71F30A1A3888" modified="2017-04-12" version="1">MKQYHDLLRHVMETGVVKADRTGTGTRSVFGYQMRFDLSEGFPLVTTKKVHTRSVFGELLWFLRGDTNLAWLHENRISIWDEWADADGDLGPIYGYQWRSWPTPDGGHVDQIARVVESLRTNPDSRRHIVSAWNVADVDDMALPPCHTLFQFYVAPADDGGPGILSCQLYQRSADVFLGVPFNIASYALLTHLVAQVTGLRVGEFVHTLGDAHIYSNHVDQVAEQLARELRPLPTLVLNPEVTEIDRFELADISVTGYDPHPAIKAPIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFU9</accession>
    <name>A0A1Q2CFU9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">dITP/XTP pyrophosphatase</fullName>
            <ecNumber evidence="6">3.6.1.66</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Non-canonical purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Non-standard purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nucleoside-triphosphate diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nucleoside-triphosphate pyrophosphatase</fullName>
            <shortName evidence="6">NTPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_09495</name>
        <name evidence="9" type="ORF">SAMN05428934_102407</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + ITP = diphosphate + H(+) + IMP</text>
            <dbReference type="Rhea" id="RHEA:29399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + XTP = diphosphate + H(+) + XMP</text>
            <dbReference type="Rhea" id="RHEA:28610"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:61314"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dITP + H2O = dIMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28342"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61194"/>
            <dbReference type="ChEBI" id="CHEBI:61382"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.66" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY59931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09495"/>
    <dbReference type="EnsemblBacteria" id="AQP44989">
        <property type="protein sequence ID" value="AQP44989"/>
        <property type="gene ID" value="RPIT_09495"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59931">
        <property type="protein sequence ID" value="SDY59931"/>
        <property type="gene ID" value="SAMN05428934_102407"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09495"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035870">
        <property type="term" value="F:dITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:nucleoside-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036222">
        <property type="term" value="F:XTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009146">
        <property type="term" value="P:purine nucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00515">
        <property type="entry name" value="HAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01405">
        <property type="entry name" value="Non_canon_purine_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020922">
        <property type="entry name" value="dITP/XTP_pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="Ham1p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="PTHR11067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00042">
        <property type="entry name" value="TIGR00042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="11"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="158"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="186"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY59931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="202" mass="21921" checksum="11685D83660AFCAF" modified="2017-04-12" version="1">MKRPERLVLATNNPKKLNELRRILGSAGLDVEVLGLRDVARYPEPDETERTFEGNAFLKATAAARETGLVALADDSGLEVDELGGMPGVRSARWAGPAQDDEDNNALLLAQLDGVPRERRSARFVCALAMVSPDGERRVWHGTMHGHIADAPEGEGGFGYDPLFVPAGMTVTSAELTPDEKDSISHRGIAVRKFVDYLVELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG10</accession>
    <name>A0A1Q2CG10_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bifunctional purine biosynthesis protein PurH</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="8">Phosphoribosylaminoimidazolecarboxamide formyltransferase</fullName>
                <ecNumber evidence="8">2.1.2.3</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">AICAR transformylase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="8">IMP cyclohydrolase</fullName>
                <ecNumber evidence="8">3.5.4.10</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">ATIC</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="8">IMP synthase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="8">Inosinicase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="8" type="primary">purH</name>
        <name evidence="10" type="ORF">RPIT_09845</name>
        <name evidence="11" type="ORF">SAMN05428934_102337</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6S)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide = (6S)-5,6,7,8-tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:22192"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="2.1.2.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:18445"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="EC" id="3.5.4.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">The IMP cyclohydrolase activity resides in the N-terminal region.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the PurH family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.3" evidence="8"/>
    <dbReference type="EC" id="3.5.4.10" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY57978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09845"/>
    <dbReference type="EnsemblBacteria" id="AQP45051">
        <property type="protein sequence ID" value="AQP45051"/>
        <property type="gene ID" value="RPIT_09845"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57978">
        <property type="protein sequence ID" value="SDY57978"/>
        <property type="gene ID" value="SAMN05428934_102337"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09845"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00133"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003937">
        <property type="term" value="F:IMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004643">
        <property type="term" value="F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00139">
        <property type="entry name" value="PurH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024051">
        <property type="entry name" value="AICAR_Tfase_dup_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002695">
        <property type="entry name" value="PurH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692">
        <property type="entry name" value="PTHR11692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01808">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000414">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00798">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="SSF52335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00355">
        <property type="entry name" value="purH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MGS-like" evidence="9">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP45051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY57978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="517" mass="54303" checksum="1F63797BB2B24F6B" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG66</accession>
    <name>A0A1Q2CG66_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_10160</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10160"/>
    <dbReference type="EnsemblBacteria" id="AQP45109">
        <property type="protein sequence ID" value="AQP45109"/>
        <property type="gene ID" value="RPIT_10160"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10160"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
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    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01596">
        <property type="entry name" value="Methyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="217" mass="22998" checksum="25EAEB0ADCD008A5" modified="2017-04-12" version="1">MNKRATHLEPPNAASWAFAEDYVEPSAEVAQARDDATLGGLTPVTTGVAATLKVLTRAIGAKAVVEVGTVMGGSGLSFLEGMGPDGILTSIDAEADNQIPARQIFNRAGVPSSRFRLIAGSPIEIMPKLRDGAYDIVFINGDKLEYVEYVAGSLRLLRHGGLLIVNDALWHNKVADPNDETDESIIIREALDAVTTSESYTQALLPAGNGLLLAVKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG91</accession>
    <name>A0A1Q2CG91_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CBS domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_10325</name>
        <name evidence="4" type="ORF">SAMN05428934_102240</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10325"/>
    <dbReference type="EnsemblBacteria" id="AQP45139">
        <property type="protein sequence ID" value="AQP45139"/>
        <property type="gene ID" value="RPIT_10325"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55323">
        <property type="protein sequence ID" value="SDY55323"/>
        <property type="gene ID" value="SAMN05428934_102240"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10325"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04623">
        <property type="entry name" value="CBS_pair_bac_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044725">
        <property type="entry name" value="CBSX3_CBS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="8"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="76"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY55323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="142" mass="15228" checksum="9389326396A34DB5" modified="2017-04-12" version="1">MKINDVIKTKGTTVITARSDSSVAELVALLNEHRIGAVVITDDGKSVTGIAGERDVVQALGRYGASALDRSIGEIMGTEIHTCGPDDEIEAVAGSMTEHRARHLPVIESGRYVAIVSIGDIVKSRIDQLQAEREHLVNYLHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGB6</accession>
    <name>A0A1Q2CGB6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Plasmid maintenance system killer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10445</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10445"/>
    <dbReference type="EnsemblBacteria" id="AQP45162">
        <property type="protein sequence ID" value="AQP45162"/>
        <property type="gene ID" value="RPIT_10445"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10445"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007711">
        <property type="entry name" value="HigB-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40266">
        <property type="entry name" value="PTHR40266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05015">
        <property type="entry name" value="HigB-like_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="93" mass="11124" checksum="45EFF8285C5F426C" modified="2017-04-12" version="1">MIRSFGSKDTERLWRRERVRSIYHRIHRVALRKLRQVGSAESIEDLRVPPGNRFEALKGDRAGQHSIRINDEWRIWFVRTDAGPEEVEIVDYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGD9</accession>
    <name>A0A1Q2CGD9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_10545</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10545"/>
    <dbReference type="EnsemblBacteria" id="AQP45181">
        <property type="protein sequence ID" value="AQP45181"/>
        <property type="gene ID" value="RPIT_10545"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10545"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003714">
        <property type="entry name" value="PhoH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02562">
        <property type="entry name" value="PhoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13638">
        <property type="entry name" value="PIN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="domain" description="PINc" evidence="6">
        <location>
            <begin position="20"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="445" mass="48288" checksum="9EA5FBC11CCD5980" modified="2017-04-12" version="1">MLNASTQTSPSVVPAPTTIRTYVIDTSVLLSDPRAILRFAEHNVVLPLVVITELEAKRHHPELGFFARTALRLLDDLRARHGRLDTPLATNDQGGNLRVELNHTDPASLPAGFRLGDNDSRILAVALNYANEGHDVVLVTKDLPLRVKAAAVGLGAEEYRNELPLQAGYTGMTEVDVTTDTVSALYDEGVVTVDVDAPVHSGVVLHAPGSSALGRKLPDGRIRLIQQDGEVFGIHGRSAEQRVALDLLMDDSIGIVSLGGRAGTGKSALALCAGLDAVMEQSKHSKVMVFRPLYPVGGQDLGYLPGTNEEKMQPWGQAVFDTLSSVTNKYVIDELLAREMIEVLPLTHIRGRSLHDAFIIVDEAQSLERNVLLTVLSRIGQNSRVVLTHDVAQRDNLRVGRHDGVVAVVEKLKGHPLFAHVTLTRSERSPIAALVTELLEVDELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGE9</accession>
    <name>A0A1Q2CGE9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10565</name>
        <name evidence="3" type="ORF">SAMN05428934_102192</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY53859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10565"/>
    <dbReference type="EnsemblBacteria" id="AQP45184">
        <property type="protein sequence ID" value="AQP45184"/>
        <property type="gene ID" value="RPIT_10565"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY53859">
        <property type="protein sequence ID" value="SDY53859"/>
        <property type="gene ID" value="SAMN05428934_102192"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10565"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025443">
        <property type="entry name" value="DUF4307"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14155">
        <property type="entry name" value="DUF4307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY53859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="136" mass="14264" checksum="86370182721F8948" modified="2017-04-12" version="1">MDTVTPEDQARLAQRYPKASPIDYVLGVGAGLATLAAIGLVIASGIEQSTPPVAGMVRSFEVTSPSEITAELVIQRENPSDAVECRLYAQAESYEKVAEDIIGIAPGTETLTSVDISLKTVKEATAITLDACRVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGI0</accession>
    <name>A0A1Q2CGI0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10760</name>
        <name evidence="2" type="ORF">SAMN05428934_102153</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY52685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10760"/>
    <dbReference type="EnsemblBacteria" id="AQP45216">
        <property type="protein sequence ID" value="AQP45216"/>
        <property type="gene ID" value="RPIT_10760"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY52685">
        <property type="protein sequence ID" value="SDY52685"/>
        <property type="gene ID" value="SAMN05428934_102153"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10760"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029046">
        <property type="entry name" value="LolA/LolB/LppX"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89392">
        <property type="entry name" value="SSF89392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY52685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="406" mass="42953" checksum="E4CAB968168B8409" modified="2017-04-12" version="1">MTESKADRRSPLRSPWAVPIVVAGAVVASLAAQPLLAVGESNDLPDISAEELVARVLEAEPQPMSGTVVHTARLGLPDLLFTEATGADPMSLLGGSSTLKVWTDGEQRSRVALLGAVSEYSVVADGADVWTYSSSDDEAVHYSVSDADRARLEAMSEKARAEALARKAELPTPQEAAAEALAKAEESSSISIDTQTTIAGRDVYQVVVAPDTDATLVERVVVAVDGETMIPLRVQTWSTQDQTAPAVEISFTDVSFQMPNESVFEFSPPAGATERDVVVPLPDEDGEMPAHEGTEHQKPTVTGEGWATVVEFQGMDMAELVSSDPGTMSGMPDRLVGSDEAQDLMDEFTPDHSGGMGLDNAALFEQLTTEVPEGRLLSSTLLSILMTDDGRVLVGAVPADTLRAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGJ9</accession>
    <name>A0A1Q2CGJ9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase A</fullName>
            <ecNumber evidence="6">2.1.1.182</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethyladenosine transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmA</name>
        <name evidence="6" type="synonym">ksgA</name>
        <name evidence="9" type="ORF">RPIT_10950</name>
        <name evidence="10" type="ORF">SAMN05428934_102113</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:19609"/>
            <dbReference type="Rhea" id="RHEA-COMP:10232"/>
            <dbReference type="Rhea" id="RHEA-COMP:10233"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74493"/>
            <dbReference type="EC" id="2.1.1.182"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.182" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY51451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10950"/>
    <dbReference type="EnsemblBacteria" id="AQP45249">
        <property type="protein sequence ID" value="AQP45249"/>
        <property type="gene ID" value="RPIT_10950"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY51451">
        <property type="protein sequence ID" value="SDY51451"/>
        <property type="gene ID" value="SAMN05428934_102113"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10950"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052908">
        <property type="term" value="F:16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00607">
        <property type="entry name" value="16SrRNA_methyltr_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="rADc" evidence="8">
        <location>
            <begin position="37"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY51451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="283" mass="29919" checksum="701AA2CF995D558B" modified="2017-04-12" version="1">MPELGLLDPNSVRRIAAELDLKPTKQRGQNFVVDPNTVRRIVALSGVGASDVVLEIGPGLGSLTLGLLETGAEVVAVEIEERLAERLERTVQDRMGEEAAGRLRVVAADALRVEELPGGAPTALVANLPYNVSVPVLLRMLELYPGWQTGLVMVQLEVADRLVAPPGSKVYGVPSAKTAWYAQTARVGTVPPKVFWPVPNVDSGLVRIDRRDPPATSASREATFAVIDAAFSQRRKMLRAALGGLFGSAAAAAEAITAAGVDPTLRGEMLDVAGFASIAEQLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGU4</accession>
    <name>A0A1Q2CGU4_9ACTN</name>
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        <submittedName>
            <fullName evidence="6">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_11480</name>
        <name evidence="6" type="ORF">SAMN05428934_1027</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY48155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11480"/>
    <dbReference type="EnsemblBacteria" id="AQP45342">
        <property type="protein sequence ID" value="AQP45342"/>
        <property type="gene ID" value="RPIT_11480"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY48155">
        <property type="protein sequence ID" value="SDY48155"/>
        <property type="gene ID" value="SAMN05428934_1027"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11480"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="8"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY48155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="328" mass="34838" checksum="999EE22FC85A8B28" modified="2017-04-12" version="1">MSRRAPRANLRDIAEVAGVSMQTASRVVRGVDTVAEATRERVLRAVRELNYQPNLAARSLSARRTGSVHVIDAVPLYHGHATTFVAVCQHLSALDLHVSITVIRTDDFESLALTDLVPVGADGVIVLGGRSESNGWVSRVAAAVPTVYVGQAEALPDTVVGVAVDHHRGASLAVEHLVERGARRIVHVAGPQDWNDAQLRREGYEEACRAAGIEPTVLHADSWEAAAAGPLIDELPPDTDAIFAANDQLALRCLQGLQRSGRSVPGDVRVVGFDDAPGADSYLPPLTTIRQDFKTVGERAAAALGQLLDGGHPAAELIVPTLVVREST</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGX0</accession>
    <name>A0A1Q2CGX0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylethanolamine N-methyltransferase /phosphatidyl-N-methylethanolamine N-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11255</name>
        <name evidence="3" type="ORF">SAMN05428934_10252</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY49647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11255"/>
    <dbReference type="EnsemblBacteria" id="AQP45300">
        <property type="protein sequence ID" value="AQP45300"/>
        <property type="gene ID" value="RPIT_11255"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY49647">
        <property type="protein sequence ID" value="SDY49647"/>
        <property type="gene ID" value="SAMN05428934_10252"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11255"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="41"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY49647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="200" mass="22012" checksum="ED8BB43E411471DE" modified="2017-04-12" version="1">MNRRLDHLAASQYDLVSAPLERWILGPQRPWIASRSSGEVLEVGVGTGANFPHYAGDVRLTALELSPGMLAQAKAKAETLGLDVRFIEGDAQELPFEEATFDTVVSTFALCGIPDNRLAIAEMVRVLRPGGSLVLADHVVSTVAPVRWAQRALETITIRTNGEYFTRRQLPIVEEFGMRVVDSDRHQLGAIERLHAVKPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGY5</accession>
    <name>A0A1Q2CGY5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycine betaine/proline transport system permease protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Glycine/betaine ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_11745</name>
        <name evidence="7" type="ORF">SAMN05428934_106126</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11745"/>
    <dbReference type="EnsemblBacteria" id="AQP45388">
        <property type="protein sequence ID" value="AQP45388"/>
        <property type="gene ID" value="RPIT_11745"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93462">
        <property type="protein sequence ID" value="SDY93462"/>
        <property type="gene ID" value="SAMN05428934_106126"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11745"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="95"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY93462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="306" mass="32332" checksum="9C529B33F2BDDDAA" modified="2017-04-12" version="1">MTLLDTGLVPRIPVGQWIDSGIDWITTNLDALLDVISDAGTSVTEGLAWLLLLPHPLIMVAIFGLLSWLVRSWKLAVGVAISFLLIISMNQWEQAMQTLALVLIATLTAVIIAVPLGIWAARSDTVSAILRPVLDLMQTMPAFVYLIPAVTFFSIGVVPGLFSTIIFALPPGVRLTELGIRQVDSETVEAGQSFGATDWEILTGIQLPLAVRSIMAGVNQVIMLALSMAVIAGMVGADGLGKEVVSALATINIAKGAEAGLAIVFLAIFLDRFTSALGAPADHSSSLLATWKKKRTAKSIHAATAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH03</accession>
    <name>A0A1Q2CH03_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Osmoprotectant transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_11725</name>
        <name evidence="7" type="ORF">SAMN05428934_106130</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11725"/>
    <dbReference type="EnsemblBacteria" id="AQP45384">
        <property type="protein sequence ID" value="AQP45384"/>
        <property type="gene ID" value="RPIT_11725"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93543">
        <property type="protein sequence ID" value="SDY93543"/>
        <property type="gene ID" value="SAMN05428934_106130"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11725"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="132"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="15"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY93543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="221" mass="23016" checksum="6E3E1484B0D7FA5C" modified="2017-04-12" version="1">MTWLTYNWGWALELLWAHLLLAVPAIVASVLISVPLGRLAHRRPRAGGTVLGFASLLYAIPALPLLIVIPALTGTSIRSSATMIIALTIYGVALLVRSAADAFSSVDTTVSDAAVAIGHSPRSVFWRVELPLAVPVIVAGTRVVTVSTVGLVTIGALVGVPNLGTLLTDGFQRGITAEVVTGVVLTVVLALVLDALLLAVGRALTPWRRTPARVKPTAVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH23</accession>
    <name>A0A1Q2CH23_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45411">
        <property type="protein sequence ID" value="AQP45411"/>
        <property type="gene ID" value="RPIT_11870"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11870"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="212" mass="22485" checksum="1CEC0930F5A27517" modified="2017-04-12" version="1">MRPHLVERHDLAADAFLLAGLIFLIGILIQTFAVFGFDGEATLSMWTELIGMAAIVVAVIGAPLAVWVLHGHHLKIRDALGALLGLVVGGVAGIAVFFLVFQLWRFVPAVFDRDQYGPLDLGILMALAAAGFLVWPVKRAIVDLRGERRQVRVDGVRIGALAALVAVVLVSVFLGQAEVGLWLVPIGAGAAMAIIGAELIEGRLARKSVATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH29</accession>
    <name>A0A1Q2CH29_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">LemA protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_11590</name>
        <name evidence="8" type="ORF">SAMN05428934_106157</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LemA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY94116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11590"/>
    <dbReference type="EnsemblBacteria" id="AQP45360">
        <property type="protein sequence ID" value="AQP45360"/>
        <property type="gene ID" value="RPIT_11590"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY94116">
        <property type="protein sequence ID" value="SDY94116"/>
        <property type="gene ID" value="SAMN05428934_106157"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11590"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023353">
        <property type="entry name" value="LemA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007156">
        <property type="entry name" value="MamQ_LemA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34478">
        <property type="entry name" value="PTHR34478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04011">
        <property type="entry name" value="LemA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140478">
        <property type="entry name" value="SSF140478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="196"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="212"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="228"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="243"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY94116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="260" mass="29301" checksum="DA15BA5E92F81473" modified="2017-04-12" version="1">MPPWLIVIIVLLVIALAVVGWGVATYNGFVRSRNLIQESWRQIDVELNRRYELIPNLVETVRGYAAHERNTLEQITALRNNARALAGQSGGQPTEQRAAVEQELTQAVHNLLVSVEAYPDLKSNTNFIELQRELTDTEDRIAAARRFYNANVRDYNTRIESVPSNVIANFANFEKATYFEVNDPMVRQAPDVNFGEISQRPAGAPEQQQIDAPRQGEFQQPYQAPQQQPAPQQQPAPQQQPATPPQQQNQQGGYQPPFTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH42</accession>
    <name>A0A1Q2CH42_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Carbohydrate ABC transporter membrane protein 1, CUT1 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_11675</name>
        <name evidence="7" type="ORF">SAMN05428934_106140</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11675"/>
    <dbReference type="EnsemblBacteria" id="AQP45375">
        <property type="protein sequence ID" value="AQP45375"/>
        <property type="gene ID" value="RPIT_11675"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93744">
        <property type="protein sequence ID" value="SDY93744"/>
        <property type="gene ID" value="SAMN05428934_106140"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11675"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="82"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY93744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="305" mass="33172" checksum="8A9B8986F94A02A8" modified="2017-04-12" version="1">MSTTPDTARPKGYGSKRRRQERATATAFLAPALILCGLLLYAPFLYTSYLSLTEYNGLGDPEFVGLDKFEQLFQDPNILTSMLNTFMWVVGTLVMPVGLGLVIAVLAHGLKGSFWFRLPFLLPYAISGIAVGVIFAFILQTNGALTQALELFNLPFADSRWLLDWPLNTFVMILAATWQGAGVNALLFGVGLQSIPKEPLEAARVDGATGWSLFKNITWPMLAPMTTVVVGLSIVGSLKTFDIVWGMTKGGPGRASETLAITMYKSSFMLNDYGLGAAVALLLTIVTVSASLLYLRRQLAPAREF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH74</accession>
    <name>A0A1Q2CH74_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcription regulator of the Arc/MetJ class</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_12230</name>
        <name evidence="2" type="ORF">SAMN05428934_10630</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY91332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12230"/>
    <dbReference type="EnsemblBacteria" id="AQP45476">
        <property type="protein sequence ID" value="AQP45476"/>
        <property type="gene ID" value="RPIT_12230"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY91332">
        <property type="protein sequence ID" value="SDY91332"/>
        <property type="gene ID" value="SAMN05428934_10630"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12230"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014447">
        <property type="entry name" value="UCP006909"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006909">
        <property type="entry name" value="UCP006909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY91332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="97" mass="11345" checksum="8C4994B2F790EE86" modified="2017-04-12" version="1">MIFKRVGDTRPYPDHGYTHKQWIAIAPHQVRLDELVTTKRTLDLEALLEEDSTFYGDLFAHVVAYRGELYLEDGLHRALRAALQQRQTMHARVLELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHF9</accession>
    <name>A0A1Q2CHF9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Ribokinase</fullName>
            <shortName evidence="10">RK</shortName>
            <ecNumber evidence="3 10">2.7.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rbsK</name>
        <name evidence="13" type="ORF">RPIT_12625</name>
        <name evidence="14" type="ORF">SAMN05428934_104161</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + D-ribose = ADP + D-ribose 5-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13697"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:47013"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="10">Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the carbohydrate kinase pfkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.15" evidence="3 10"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY79492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12625"/>
    <dbReference type="EnsemblBacteria" id="AQP45544">
        <property type="protein sequence ID" value="AQP45544"/>
        <property type="gene ID" value="RPIT_12625"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY79492">
        <property type="protein sequence ID" value="SDY79492"/>
        <property type="gene ID" value="SAMN05428934_104161"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12625"/>
    <dbReference type="UniPathway" id="UPA00916">
        <property type="reaction ID" value="UER00889"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004747">
        <property type="term" value="F:ribokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019303">
        <property type="term" value="P:D-ribose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01174">
        <property type="entry name" value="ribokinase"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011877">
        <property type="entry name" value="D_ribokin"/>
    </dbReference>
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        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
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    <keyword evidence="7 10 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 11" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="12"/>
            <end position="305"/>
        </location>
    </feature>
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            <begin position="20"/>
            <end position="22"/>
        </location>
    </feature>
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        <location>
            <begin position="48"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
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            <position position="263"/>
        </location>
    </feature>
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            <position position="148"/>
        </location>
        <ligand>
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        </ligand>
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            <position position="189"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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            <end position="235"/>
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        </ligand>
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            <end position="263"/>
        </location>
        <ligand>
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            <position position="263"/>
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        <ligand>
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        </ligand>
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        <location>
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        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
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        <location>
            <position position="298"/>
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        <ligand>
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        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000691"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_01987"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU003704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP45544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY79492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="316" mass="31920" checksum="2262B453ECA819C4" modified="2017-04-12" version="1">MDSGKSANRSGKVVVVGSINVDLSVDVVRHPMPGETLPGRDVVMGPGGKGANQAVAAARLGASVAMVGAVGDDANAAVALSQITASGLDRTHVRQAPRATGLAIVVVDADGENSIIVVPGANSLVDADAVEAAADAVRTAHVVVAQGEIPASGTIRAAELSSGRFVLNLAPVMELPVEVIHKADPLVVNEHEAGLVLAMLDRDREIPLGETHSDVALALIEAGVRSVVMTLGARGSLVVDHQSELTSVPAATVTAVDSTGAGDAFVGALVSRLAEGESLVDAARFASRVGAFACTRPGAQESYPDLDDELPALPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHM8</accession>
    <name>A0A1Q2CHM8_9ACTN</name>
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        <submittedName>
            <fullName evidence="6">ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Cellobiose ABC transporter membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_12745</name>
        <name evidence="7" type="ORF">SAMN05428934_104138</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY78813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12745"/>
    <dbReference type="EnsemblBacteria" id="AQP45565">
        <property type="protein sequence ID" value="AQP45565"/>
        <property type="gene ID" value="RPIT_12745"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY78813">
        <property type="protein sequence ID" value="SDY78813"/>
        <property type="gene ID" value="SAMN05428934_104138"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12745"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="P:transmembrane transport"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TM1"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="77"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY78813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="310" mass="34526" checksum="813AD03526463ACD" modified="2017-04-12" version="1">MKELTWRQRLSRFDVKASPYLYISPFFILFFIVGLFPLAYTAWVSVHEWHLIGGQGDLVGFTNYTDVVQQPNFYKALRNTFSIFLLSSVPQVLAAIVIAYLLDTNLRAKTFWRMGVLLPFVVAPVAVSLIFAKIFADQSGLVNAVLELMGATGIAWHGDPFAAHVAIATMVNFRWTGYNALIFLAAMQAIPREIYEAAIVDGAARWRTFFSVTVPMLRPTIIFVVITSTIGGLQIFDEPRMFDTLGQGGADRQWMTLTMYIYELGWGAQKNFGRAAAVSWLLFLIIVLVGVVNFLITRSIASSASGKAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHM9</accession>
    <name>A0A1Q2CHM9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C5-epim_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_13035</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45617">
        <property type="protein sequence ID" value="AQP45617"/>
        <property type="gene ID" value="RPIT_13035"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13035"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047464">
        <property type="term" value="F:heparosan-N-sulfate-glucuronate 5-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015012">
        <property type="term" value="P:heparan sulfate proteoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010598">
        <property type="entry name" value="C5-epim_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039721">
        <property type="entry name" value="C5-epimerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13174">
        <property type="entry name" value="PTHR13174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06662">
        <property type="entry name" value="C5-epim_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012230582" description="C5-epim_C domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="domain" description="C5-epim_C" evidence="3">
        <location>
            <begin position="327"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="772" mass="84580" checksum="57AA26EC85BD9868" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHQ3</accession>
    <name>A0A1Q2CHQ3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding transcriptional regulator, FrmR family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_12960</name>
        <name evidence="5" type="ORF">SAMN05428934_10495</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CsoR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12960"/>
    <dbReference type="EnsemblBacteria" id="AQP45603">
        <property type="protein sequence ID" value="AQP45603"/>
        <property type="gene ID" value="RPIT_12960"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY77633">
        <property type="protein sequence ID" value="SDY77633"/>
        <property type="gene ID" value="SAMN05428934_10495"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12960"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003735">
        <property type="entry name" value="Metal_Tscrpt_repr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038390">
        <property type="entry name" value="Metal_Tscrpt_repr_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33677">
        <property type="entry name" value="PTHR33677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02583">
        <property type="entry name" value="Trns_repr_metal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY77633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="102" mass="11148" checksum="FB3330CF7FE13AA9" modified="2017-04-12" version="1">MTTAEVQCHTTHGYTPEKTAYLRRLKLIEGQVRGIARMVEEDQYCIDVLTQVAAATSALKAVSLGLLNDHLAHCVADAARKGGPEADEKLDEAMQAIKRLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHR3</accession>
    <name>A0A1Q2CHR3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">MFS transporter, OFA family, oxalate/formate antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_13015</name>
        <name evidence="8" type="ORF">SAMN05428934_10484</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13015"/>
    <dbReference type="EnsemblBacteria" id="AQP45613">
        <property type="protein sequence ID" value="AQP45613"/>
        <property type="gene ID" value="RPIT_13015"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY77333">
        <property type="protein sequence ID" value="SDY77333"/>
        <property type="gene ID" value="SAMN05428934_10484"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13015"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="242"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="322"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="348"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY77333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="399" mass="40075" checksum="3F68A40F73513D75" modified="2017-04-12" version="1">MRWLALVGGVLVQVVIGGVYAWSLFGRALQPELTAVQAAVPFEVAIGMIFVGASIGGRLQDRSSPRVVALLGVLLYAAGILLASLATSPERFWVLVVGYGVIGGFGLGMAYIVPVALLQKWFPRHSAVVTGLAVGGFGFGATVTSPAAQYLIGLSPESPALAFRPLGLAYLVVGALAAAMLVSPPATAAREGASSDFTPREALGTRQWYLLTAILTVAVAAGISLISMMAGAAVDVGGLDAAGAAAAVGVLALFNGAGRIGWAALAQRVGRLKVLGAILALEGLALVALPHATGFAFLALAAVVYLCYGGAFGTLPSTAGAFFGLTHAGAIYGLMLVGWSLAGVAGPLVSSALVAGAGGYTVAFTVMGLLALAGVLLPAVTRPPRRTNLDADQVPTATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHR9</accession>
    <name>A0A1Q2CHR9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative transport protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_13240</name>
        <name evidence="9" type="ORF">SAMN05428934_10439</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAE transporter (TC 2.A.81) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY76075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13240"/>
    <dbReference type="EnsemblBacteria" id="AQP45654">
        <property type="protein sequence ID" value="AQP45654"/>
        <property type="gene ID" value="RPIT_13240"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY76075">
        <property type="protein sequence ID" value="SDY76075"/>
        <property type="gene ID" value="SAMN05428934_10439"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13240"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006512">
        <property type="entry name" value="YidE_YbjL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06826">
        <property type="entry name" value="Asp-Al_Ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01625">
        <property type="entry name" value="YidE_YbjL_dupl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
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</entry>
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                <person name="Schumann P."/>
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            </authorList>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <sequence length="247" mass="26529" checksum="E70D11CD59835E4F" modified="2017-04-12" version="1">MADVTSLADAARIVVLSGAGLSTAAGIPDFRGPEGLWTRDPYAELVSTLSWYLRDDDVRKAAWRRRADPAMWAAEPTRAHRAIVELERQGRLRAIVTQNTDGLHQLAGNDPALVHEVHGSARTWRCEMCGKTGPMREMVDRVQGGDEDPRCPDCGGITRATVILFEEVLDTDVLQAALDAVEDCDAIVAVGTTLGVYPVAALFPLALERGAFGVIVNASETPFDADADQVVRGQLDDVLPGLLGVAE</sequence>
</entry>
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    <accession>A0A1Q2CI47</accession>
    <name>A0A1Q2CI47_9ACTN</name>
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        </source>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP45799.1"/>
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    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45799">
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        <property type="gene ID" value="RPIT_14120"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ14257"/>
        <property type="gene ID" value="SAMN05428934_1125"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14120"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ14257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="92" mass="9906" checksum="F44C9CDD0A383B8B" modified="2017-04-12" version="1">MTDDDLWDLTRTRLFWAGILANGVTSDDGAIAVEAALPARPTARGELLRLHQLATDELTGMLALLSDDEPRWADGEGTTVGDVRRLLDSDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI79</accession>
    <name>A0A1Q2CI79_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ATP-binding cassette, subfamily B</fullName>
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        <submittedName>
            <fullName evidence="10">Iron ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_14150</name>
        <name evidence="11" type="ORF">SAMN05428934_11211</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ14659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="114" mass="12482" checksum="3D7077284E50FD0F" modified="2017-04-12" version="1">MDDRIPRDEVEAFLEVRREQGREIEPALIDSMTAKIEGVVRRRYQAELQSKTRQDLASKQGQGARLTVAIISLVMAIPLTAIASGMGLVGLLIVWAGIVAVNIAFALRRPPTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIJ2</accession>
    <name>A0A1Q2CIJ2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DNA binding domain-containing protein, excisionase family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Resolvase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_14645</name>
        <name evidence="10" type="ORF">SAMN05428934_10986</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the site-specific recombinase resolvase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14645"/>
    <dbReference type="EnsemblBacteria" id="AQP45893">
        <property type="protein sequence ID" value="AQP45893"/>
        <property type="gene ID" value="RPIT_14645"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06237">
        <property type="protein sequence ID" value="SDZ06237"/>
        <property type="gene ID" value="SAMN05428934_10986"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14645"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006118">
        <property type="entry name" value="Recombinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00397">
        <property type="entry name" value="RECOMBINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51736">
        <property type="entry name" value="RECOMBINASES_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0229">DNA integration</keyword>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="8">
        <location>
            <begin position="10"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="218"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-serine intermediate" evidence="5 6">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606118-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ06237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="266" mass="28960" checksum="49648C1E3A3B1DCA" modified="2017-04-12" version="1">MKDKSAAAGLLLGYARVSTDDQDLTNQRAELHAAGCTRIFAEKITGTRRDRPELARVLDHLRPGDVVTVTRLDRLARSTRDLLDIAERIQAVGAGLRSLAEPWADTTTPAGRMVLTVFAGIAEFERSLIIDRTRNGREAAKARGVKFGPRPTLTPAQIEHARELIDRDGRTVKEAAELLAVHRSTLYRALARGEEVTKTEARRRGAFAEDALSEADALAAVDDERQEEGPAFLDGDGPAADLPPPPYRTQSLPQILAALPDDELAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIL2</accession>
    <name>A0A1Q2CIL2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chromosome partitioning protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Cobalamin biosynthesis protein CobQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14630</name>
        <name evidence="3" type="ORF">SAMN05428934_10989</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_064846209.1">
        <property type="nucleotide sequence ID" value="NZ_FNPU01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14630"/>
    <dbReference type="EnsemblBacteria" id="AQP45890">
        <property type="protein sequence ID" value="AQP45890"/>
        <property type="gene ID" value="RPIT_14630"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06300">
        <property type="protein sequence ID" value="SDZ06300"/>
        <property type="gene ID" value="SAMN05428934_10989"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14630"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="2"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ06300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="263" mass="27683" checksum="1A8CAB9968F4D488" modified="2017-04-12" version="1">MILAYCNQKGGVGKSTTVYHHARAAILDGQRVLVIDADPQGNITSVLTEDMQEGDVGVADALSSRSSDTLADVLVPGIWEGLTVAPTVGDNLADVRNELVISSEPGRESRLRAQLAAIQTEYDLVLIDCGPAIDPLTISALTAADAVVIVSQSKLWSVNGLAKLMNTVSLVREHYNPRLTVAGLVLNAHEAHTLAGGHWADELTAAAEAAQLPILTPPVPKRQAIADATETARGLDEGDAQARELAAIYAAHIDQLKKGTAHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIN4</accession>
    <name>A0A1Q2CIN4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Endoglucanase Acf2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_14765</name>
        <name evidence="4" type="ORF">SAMN05428934_10967</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14765"/>
    <dbReference type="EnsemblBacteria" id="AQP45910">
        <property type="protein sequence ID" value="AQP45910"/>
        <property type="gene ID" value="RPIT_14765"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05858">
        <property type="protein sequence ID" value="SDZ05858"/>
        <property type="gene ID" value="SAMN05428934_10967"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14765"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052861">
        <property type="term" value="F:glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005200">
        <property type="entry name" value="Endo-beta-glucanase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040720">
        <property type="entry name" value="GH81_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31983">
        <property type="entry name" value="PTHR31983"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17652">
        <property type="entry name" value="Glyco_hydro81C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544529" evidence="1">
        <location>
            <begin position="18"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro81C" evidence="2">
        <location>
            <begin position="328"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ05858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="668" mass="71311" checksum="0EE87575347CDC47" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIP8</accession>
    <name>A0A1Q2CIP8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome aa3 subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_03720</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome c oxidase subunit 3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03720"/>
    <dbReference type="EnsemblBacteria" id="AQP45999">
        <property type="protein sequence ID" value="AQP45999"/>
        <property type="gene ID" value="RPIT_03720"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03720"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024791">
        <property type="entry name" value="Cyt_c/ubiquinol_Oxase_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000298">
        <property type="entry name" value="Cyt_c_oxidase-like_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035973">
        <property type="entry name" value="Cyt_c_oxidase_su3-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013833">
        <property type="entry name" value="Cyt_c_oxidase_su3_a-hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11403">
        <property type="entry name" value="PTHR11403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00510">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81452">
        <property type="entry name" value="SSF81452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50253">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="COX3" evidence="9">
        <location>
            <begin position="30"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP45999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="227" mass="25312" checksum="9F455145161D8268" modified="2017-04-12" version="1">MIAPTELPSGAIHQLPSARLNKPYGRPDTVSVGVIVWLASELMFFAALFAAYFWIRNLTNEAAASAGVASLWETNTAHLDVAFASVNTAILVLSSVTCQLAANAAEARRVSGSWLNPLRWGMREGFIITAILGSVFIAGQVWEYFTLFSEGYTISTNQYWSVFFLATGFHGIHVFGGIVAMWYVLARSYMTRTHTHEQTVGAHVVSYYWHFVDVIWIILFGVLYFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIP9</accession>
    <name>A0A1Q2CIP9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Carbohydrate ABC transporter membrane protein 1, CUT1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_14845</name>
        <name evidence="7" type="ORF">SAMN05428934_10951</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14845"/>
    <dbReference type="EnsemblBacteria" id="AQP45925">
        <property type="protein sequence ID" value="AQP45925"/>
        <property type="gene ID" value="RPIT_14845"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05568">
        <property type="protein sequence ID" value="SDZ05568"/>
        <property type="gene ID" value="SAMN05428934_10951"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14845"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="142"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="67"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ05568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="281" mass="31208" checksum="AD155E7BFDDCC7E6" modified="2017-04-12" version="1">MQRSLKKYFPLFVLPTSVAFIIAFLAPFVIGLYLSFTKFTTITNAEWVGLDNYRRALDPADGFLGSFWFTILVVVASVITVNLFAFGIAKLLTQKLKGTNVFRTIFFMPNLIGGIVLGYTWQVIINAVLANYGTTLVADWKYGYIGLILLVNWQQVGYMMVIYIAGLQNVPPELNEAAAIDGAGRWQTLRNVTIPMIMPTITICLFLTMSSAFKMFDQNLALTDGAPMDQTKMVALDIFKTMFSQIGRQGVGQAKAVLFVIVVVAIALLQLRATRSREVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIR2</accession>
    <name>A0A1Q2CIR2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Elongation factor G</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Translation elongation factor 2 (EF-2/EF-G)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_03440</name>
        <name evidence="8" type="ORF">SAMN05428934_101288</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03440"/>
    <dbReference type="EnsemblBacteria" id="AQP45994">
        <property type="protein sequence ID" value="AQP45994"/>
        <property type="gene ID" value="RPIT_03440"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30998">
        <property type="protein sequence ID" value="SDY30998"/>
        <property type="gene ID" value="SAMN05428934_101288"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03440"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
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        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EFG_IV" evidence="6">
        <location>
            <begin position="484"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="EFG_C" evidence="5">
        <location>
            <begin position="604"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="339"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY30998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="693" mass="74605" checksum="FA254A2E5B022E0E" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIR6</accession>
    <name>A0A1Q2CIR6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase E</fullName>
            <ecNumber evidence="6">2.1.1.193</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_04975</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>S-adenosyl-L-methionine + uridine(1498) in 16S rRNA = H(+) + N(3)-methyluridine(1498) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42920"/>
            <dbReference type="Rhea" id="RHEA-COMP:10283"/>
            <dbReference type="Rhea" id="RHEA-COMP:10284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74502"/>
            <dbReference type="EC" id="2.1.1.193"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the RNA methyltransferase RsmE family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.193" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04975"/>
    <dbReference type="EnsemblBacteria" id="AQP46026">
        <property type="protein sequence ID" value="AQP46026"/>
        <property type="gene ID" value="RPIT_04975"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04975"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006700">
        <property type="entry name" value="rRNA_ssu_MeTrfase-E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30027">
        <property type="entry name" value="PTHR30027"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04452">
        <property type="entry name" value="Methyltrans_RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015601">
        <property type="entry name" value="MTase_slr0722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00046">
        <property type="entry name" value="TIGR00046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP46026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="242" mass="25571" checksum="B2D376CD9BA4D89D" modified="2017-04-12" version="1">MTDPLFFASFGDDVAAGLRLTVSGEEAHHAAVKRVAPGERVLLANGEGLGVRAVVVDVGRRELEVEVVEVLRASSPPLVWGVAQALAKGDRSEIAVQMATELGARRILAWQASRSIVRWQGDRGDKALEKWRATAREAVKQSRRLWTPEVLAASTADVAEAIRDADVALVLHEDADLHIAEVELAAAGTGLLVVGPEGGISPDELTRFAEAGALAVRISDGVLRTSTAAAVALGQLDVVARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIT7</accession>
    <name>A0A1Q2CIT7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_04800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04800"/>
    <dbReference type="EnsemblBacteria" id="AQP46022">
        <property type="protein sequence ID" value="AQP46022"/>
        <property type="gene ID" value="RPIT_04800"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04800"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PG_binding_1" evidence="3">
        <location>
            <begin position="17"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="YkuD" evidence="4">
        <location>
            <begin position="108"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP46022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="221" mass="24576" checksum="BD85DFF2E8FB78E0" modified="2017-04-12" version="1">MYNVLRPGPAILAPGSQGDDVKDLQARLKQIGWFHDAIAETYGPKTTEAVRGFQEKRQIPVTGEVDQRTLDRLYGMTRKPTSDELNNVVPEKAPTPAMVLDDRCLQGRVICISKSQRRLAWVIDGKIQSTMDVRFGSVQTPTRNGVFSVYWKSRDHVSSLYDSPMPFALFFSGGQAVHYSADFAARGYDGASHGCVNVRDKQAVMALFDASREGDKVVVYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIW5</accession>
    <name>A0A1Q2CIW5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transaldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_03225</name>
        <name evidence="2" type="ORF">SAMN05428934_101246</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03225"/>
    <dbReference type="EnsemblBacteria" id="AQP45990">
        <property type="protein sequence ID" value="AQP45990"/>
        <property type="gene ID" value="RPIT_03225"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29705">
        <property type="protein sequence ID" value="SDY29705"/>
        <property type="gene ID" value="SAMN05428934_101246"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03225"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="PTHR10683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY29705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="358" mass="40048" checksum="101F45615A647DA2" modified="2017-04-12" version="1">MTDQYTPGPLLEAARNTPTALWNDSSDLEELKQSISFGGVGATCNPVIAYTTISQHLDVWKPRIKAIADANPTWGESEIGWQAVKDMSIEAAEILKPIYDEHKGRNGRLSVQTDPRLHRDAKALADQAEEFHQLAENIVVKIPATKTGLEAIEDATSRGVSINVTVSFSVPQAVRAAEAIERGLQKREAEGHDVSEMGPVVTIMVGRLDDWLKHVVARDKLFIDPSALEWAGVACMKKAYQIFKERGFRARVLSAAFRNVHHWSELVGGDLVVSPPFKWQQIINGSDYEPTSRIEEPVRQEYLDELMKIEDFRRAYDVDGMTLEEFEEFGPTRKTLRQFLQADADLDALVRDVLVPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ01</accession>
    <name>A0A1Q2CJ01_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA polymerase III subunit delta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04855"/>
    <dbReference type="EnsemblBacteria" id="AQP46025">
        <property type="protein sequence ID" value="AQP46025"/>
        <property type="gene ID" value="RPIT_04855"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04855"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010372">
        <property type="entry name" value="DNA_pol3_delta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005790">
        <property type="entry name" value="DNA_polIII_delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06144">
        <property type="entry name" value="DNA_pol3_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01128">
        <property type="entry name" value="holA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_pol3_delta" evidence="1">
        <location>
            <begin position="48"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="321" mass="33716" checksum="7B2722E52A5C9E32" modified="2017-04-12" version="1">MTSAFGTSLLITGPESLLASRIVADTKRRALAAHPEADINEIQATELADSMLSEVVGGSLFSSHIIAIIDDVGACPPEVVDQLVAVAADPPEDLCLILVHQGGMKGKGLVDKLKKAKVQVEQVAAIKPWELPKFVAAEAKRHKVRISQEAAGELVAAVGHDLRSLAAAVSQLASDAGSGEIDAALIRRYFAGRAEVTSFAVADAVLAGNASLALERLRWALSTGAAPVLVTSAMAGAFRGMGRYLDAQGSRLSDADMARQIGIPYWKIKDYSRAASNWQSGAVASAIRIIGIADGEVKGAATNADFALERMVLGVLKLRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ18</accession>
    <name>A0A1Q2CJ18_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_07265</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07265"/>
    <dbReference type="EnsemblBacteria" id="AQP46073">
        <property type="protein sequence ID" value="AQP46073"/>
        <property type="gene ID" value="RPIT_07265"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07265"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="32"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="158"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="158"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP46073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="259" mass="28524" checksum="3EF74E8462FDE43F" modified="2017-04-12" version="1">MRPRTLPQHREGVGWRAGSVNNGCMAEPRRSSVLVIDDERPLAGIVASYLNKAGFDTALAYTGPDGVSSAQDLDPDVIILDLGLPGIDGIEVCRQIRLFSDCYILMLTARADEVDKLIGLSVGADDYLTKPFSPRELVARVNTVLRRPRRQTHGTQPAPPREFGRLRVDAEGRDVWVDDQQVGLTRTEFDILDALSGRPNVALSRRQIIDSVWGPGWVGDDHVVDVHVANLRKKLDDPPAEPRYILTVRGVGYRMGPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ29</accession>
    <name>A0A1Q2CJ29_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Tyrosine recombinase XerD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">xerD</name>
        <name evidence="15" type="ORF">RPIT_08070</name>
        <name evidence="16" type="ORF">SAMN05428934_11354</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1T</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1</strain>
        </source>
    </reference>
    <reference evidence="15" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the 'phage' integrase family. XerD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ17037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08070"/>
    <dbReference type="EnsemblBacteria" id="AQP46083">
        <property type="protein sequence ID" value="AQP46083"/>
        <property type="gene ID" value="RPIT_08070"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ17037">
        <property type="protein sequence ID" value="SDZ17037"/>
        <property type="gene ID" value="SAMN05428934_11354"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08070"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009037">
        <property type="term" value="F:tyrosine-based site-specific recombinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01808">
        <property type="entry name" value="Recomb_XerC_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01807">
        <property type="entry name" value="Recomb_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011932">
        <property type="entry name" value="Recomb_XerD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023009">
        <property type="entry name" value="Tyrosine_recombinase_XerC/XerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02225">
        <property type="entry name" value="recomb_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 11" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0229">DNA integration</keyword>
    <keyword evidence="9 11" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8 11 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="14">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="13">
        <location>
            <begin position="106"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="273"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="11">
        <location>
            <position position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="AQP46083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="SDZ17037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="302" mass="32519" checksum="367EC076E342B5DA" modified="2017-04-12" version="1">MIDDAVGDYLNHIRAERGLAANTVAAYRRDLARYVAFLRARGVEEVGEVTAVEVSEFVRELSVAQARSSVARQVVSVRNFHQFAAEEGLAPGNPAAEVSPPKQEQRLPKALTVDEVTRIMEAPDRTDVVGLRDAALLELLYGTGARVSEVCGLDVDDVTTALAEPDAGLRLLGKGGKERAVPLGSYAADALEAYLVRSRPVLAASASKHDPGLLLNQRGRRLSRQSAWAVIQRAAADAGVDREVSPHSLRHSFATHLLDGGADLRVVQELLGHASVATTQIYTLVTIDHLREVHAAAHPRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ33</accession>
    <name>A0A1Q2CJ33_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Oxygen sensor histidine kinase NreB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Nitrogen regulation protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">RPIT_09745</name>
        <name evidence="15" type="ORF">SAMN05428934_102356</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1T</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1</strain>
        </source>
    </reference>
    <reference evidence="14" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY58551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09745"/>
    <dbReference type="EnsemblBacteria" id="AQP46112">
        <property type="protein sequence ID" value="AQP46112"/>
        <property type="gene ID" value="RPIT_09745"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY58551">
        <property type="protein sequence ID" value="SDY58551"/>
        <property type="gene ID" value="SAMN05428934_102356"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09745"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017205">
        <property type="entry name" value="Sig_transdc_His_kinase_ChrS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037434">
        <property type="entry name" value="STHK_ChrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="15" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="13">
        <location>
            <begin position="171"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="132"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="AQP46112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="SDY58551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="369" mass="38409" checksum="084860AC367CB6CA" modified="2017-04-12" version="1">MFVGLLGIATGMAWHEQAGALVYSLAAVLLVAFLAGMAAADSMGVAGRLTWVSLLLLGNSALVLLNDSFLWVAFPLWTLAGAVLPLLASLLLTATTAALIITVLAMTGGESVAAALGPLAGAAIALGLARGVQQFEHEASEHRRLLDEVIRAQDETARLQREAGVLSERTRLAHDIHDTLAQAFSSLVLLSRAARRDPAHADHLLAQIEDAAADGLAESRRVVYALAPEETAAGGLAGPLRRLTEETAAAIGAEVSFTVDPELPNLTTTIEVALLRAAQGTLANVRQHSRATRLAVELARSGDLVLLDIVDDGVGFDPGRQSRPTMEGGYGLKALRERLANLGGGLTIETEPGGGTAVSIQLPITLEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ56</accession>
    <name>A0A1Q2CJ56_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09760"/>
    <dbReference type="EnsemblBacteria" id="AQP46113">
        <property type="protein sequence ID" value="AQP46113"/>
        <property type="gene ID" value="RPIT_09760"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09760"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012614157" evidence="2">
        <location>
            <begin position="29"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="476" mass="50234" checksum="BF979270449F4F95" modified="2017-04-12" version="1">MDESSGSALTAALIQSATAVVVASPAAAPTPDPTGSAPQTSPAGSASASPSPTPSTTATTPAGDPLASATEAALALGLPLLLAGPSLLAELDRLETRTVIGYPADGLDVGDRELIAGPDDPSALPELPGLPRTPQPAAIAVYTDADELAPEIRAVLSAAGVTPIRTVSGHPGETAESVAAAKASESVVALGSSFGDDTTLASRVAVARTAAELPGGGVTPFPGRRMIALYGHPGAPVLGMMGEQSPEESVARLQTLVAEYQALRPEENFIGAFEIITTIASASAGSDGNYSILSSFERVLPFIEAAEANDIYVVLDLQPGRSTFLDQAKRYEELLKRPWVGLALDPEWRLQPGQRHMVQIGQVEIEEVNEVGAWLAQLVRDNNLPPKVLTLHQFQPRMIINRELLDTSHDEIQYMVHVDGLGSQGAKQGTWQRILQDLPPRVYLGWKNFEDEDLPMLTPAQTLDQVVPMPDFVSYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ76</accession>
    <name>A0A1Q2CJ76_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycerate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_12560</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycerate kinase type-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12560"/>
    <dbReference type="EnsemblBacteria" id="AQP46154">
        <property type="protein sequence ID" value="AQP46154"/>
        <property type="gene ID" value="RPIT_12560"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12560"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008887">
        <property type="term" value="F:glycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031388">
        <property type="term" value="P:organic acid phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018193">
        <property type="entry name" value="Glyc_kinase_flavodox-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004381">
        <property type="entry name" value="Glycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018197">
        <property type="entry name" value="Glycerate_kinase_RE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036129">
        <property type="entry name" value="Glycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21599">
        <property type="entry name" value="PTHR21599"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02595">
        <property type="entry name" value="Gly_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006078">
        <property type="entry name" value="GlxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110738">
        <property type="entry name" value="SSF110738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00045">
        <property type="entry name" value="TIGR00045"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR006078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP46154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="368" mass="37034" checksum="C731DC2FA52D92D8" modified="2017-04-12" version="1">MNVVVAPDSFKGSARADDVARAMSDGWLAARPHDHVLLRPMADGGEGTLEVFASAVPGARWVPVTVAGPVGEPVDARWLWLPPAEDAPGGTGVVELASTCGLELLGERRAPWDARTTGLGQAIRAALDHGVSRLAVSIGSSASTDGGVGCLTALGYAFLDGDGRQIAPGARGLADVDRVDRSGAVALPPGGATVLSDVTNPLTGPRGAAAVFGPQKGLAPGDVAVADEGLRRLARVMGGDPSAAGAGAAGGTGFALMDWGAELRPGAVEVARLIGLAEAVSRADVVITGEGSFDDQSRGGKAPGLVLAEARRSGAAVGLIAGRIAPGTDLTGIAQHLTLDALAGDVEAAQRDALRWIAEAAQRLGRMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ90</accession>
    <name>A0A1Q2CJ90_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_14850</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14850"/>
    <dbReference type="EnsemblBacteria" id="AQP46196">
        <property type="protein sequence ID" value="AQP46196"/>
        <property type="gene ID" value="RPIT_14850"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14850"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="178"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="67"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP46196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="274" mass="30349" checksum="E4EA18FDD6641F66" modified="2017-04-12" version="1">MSKILIYALLVALVGLFLGPIVFIVLNSFKQKFSISSDPFAVPLGDMWAGFSNYITGIQAQNFFEAILWSFVITIGSVLIIVFLTAMLAYFIMRVKTWWTSLIYYLLVFSMVIPFQMVMFPTVKLADALGLANPVGMMVLYLGFGAGLSVFIFSGFVKSIPLEIEEAAYIDGCSPLTTYFQVVWPILKPVTITVAILNAMWIWNDYLLPYLVIGLSTRFKTIPVVVQQFVGSNGNRDMGALMAMLVLAVVPIIVFYLFAQKHIIEGVVAGSVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBG4</accession>
    <name>A0A1Q2CBG4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00300</name>
        <name evidence="3" type="ORF">SAMN05428934_10514</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY83755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43449">
        <property type="protein sequence ID" value="AQP43449"/>
        <property type="gene ID" value="RPIT_00300"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY83755">
        <property type="protein sequence ID" value="SDY83755"/>
        <property type="gene ID" value="SAMN05428934_10514"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00300"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY83755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="169" mass="17779" checksum="B920B98C27B92468" modified="2017-04-12" version="1">MDERQELNAGKASMIVLGLVAMVALGVLAWEYITTKDVTNTWAIVTLLGTGGLFLLLTRMIGGAEAPKTFLGKELPTESTAEAKAERRRAYAIDAGLFAIAMAALSVVGLSMGDAEAVTPAFLKGTTGYVVGGAIGLIGGFAIYYGFNYLVGESASRSVEKKLARYESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBJ9</accession>
    <name>A0A1Q2CBJ9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_00485</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43480">
        <property type="protein sequence ID" value="AQP43480"/>
        <property type="gene ID" value="RPIT_00485"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00485"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027791">
        <property type="entry name" value="Galactosyl_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="10"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="118"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="549" mass="61176" checksum="56D5FAB1DC4F2394" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBM4</accession>
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            <fullName evidence="3">Peptidase_C39 like family protein</fullName>
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        <name evidence="3" type="ORF">SAMN05428934_1058</name>
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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            <strain evidence="2 4">RP1T</strain>
        </source>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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            <end position="247"/>
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            <dbReference type="Pfam" id="PF13529"/>
        </source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="278" mass="29895" checksum="8E86F8C0619E0741" modified="2017-04-12" version="1">MTTFLLAMPVHAWADPGTETTDDIQFGIDYTPPSERDEQSPEAQEHIAEALLTYQTVAGLTASDQAAIEAELAELEKDNPEAVVEAREDAAAKRMSRAAAAVPPTARTFVMTHQKQANGYYCGPATASMIAKYKGKSCSQATLAGSTYLKTDANGATKWALKVMAPTLNKIVGTTEYQQIQSPTLASLKASFVNNIGENYLPVAVDTYEYANSAHYNGHPKTKNIGHWIVGHGYSRSGSTLAFHDPAQGVWSGVTVPETFTYSASGFHQWVTTNGIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBN4</accession>
    <name>A0A1Q2CBN4_9ACTN</name>
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        <submittedName>
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        </submittedName>
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        <name evidence="2" type="ORF">RPIT_00355</name>
        <name evidence="3" type="ORF">SAMN05428934_10525</name>
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        <name type="scientific">Tessaracoccus flavus</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY84064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00355"/>
    <dbReference type="EnsemblBacteria" id="AQP43455">
        <property type="protein sequence ID" value="AQP43455"/>
        <property type="gene ID" value="RPIT_00355"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY84064">
        <property type="protein sequence ID" value="SDY84064"/>
        <property type="gene ID" value="SAMN05428934_10525"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00355"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="5"/>
            <end position="180"/>
        </location>
    </feature>
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            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY84064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="325" mass="35431" checksum="849A5643A8B3BEE6" modified="2017-04-12" version="1">MSETLTMAKALNRGLRRALQADPKVLLAGEDIGKLGGVFRITEGLQAEFGENRVIDSPLAESGIIGTAVGLCMRGYRPVVEIQFDGFVFPGFSQIVTQVAKLHMRTAGQNPMPMVIRIPFGGGIGAVEHHSESPEAYFAHTPGLKVVSCSNANDAYWMIQQAIQSDDPVVFLEPKRRYHVKDTVNFSARPAPMHQANIARYGTDATLLCYGPMVKTCLDAAAVAGEEGTSLEVVDLRTLSPIDWVTITSSVRRTKRAIVVHEAPLTLGLGSEVAARLAQDLFYVMEAPVLRVAGYDMPYPPARVEEEYLPSVDRILDAVDRSLAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBN7</accession>
    <name>A0A1Q2CBN7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF368 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00695</name>
        <name evidence="3" type="ORF">SAMN05428934_10592</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY85868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43517">
        <property type="protein sequence ID" value="AQP43517"/>
        <property type="gene ID" value="RPIT_00695"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY85868">
        <property type="protein sequence ID" value="SDY85868"/>
        <property type="gene ID" value="SAMN05428934_10592"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00695"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007163">
        <property type="entry name" value="DUF368"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37308">
        <property type="entry name" value="PTHR37308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04018">
        <property type="entry name" value="DUF368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY85868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="327" mass="34487" checksum="32B172F466B8C734" modified="2017-04-12" version="1">MANPAPRPTPTSPVNRPDSVGQWFARLAKGIAVGVGAILPGLSGGVLAVIFGLYDPLIRFLANVTRNFRRNVMFFIPVGIGVGLGILGFSAVVAKAFETYAAHFTCLFIGFVIGTFPSLYRQAGKQGRSGVHFGILGAAAAGIFVLMLLGGNALIQVTPSIPVWFGSGALIGLGLIVPGMSPSNFLIYFGLYDKMAEGIKDFDFGVIIPLALGVVACVLVLAKGAAWLFDRYYAGAYHFILGMVVGSSLAIFPTVVFPAFTDEGLRESGLSLGGSVAFAVAMLVVGTIASYLFSRVEARYEAKREAIEKAANVDPDEQNPVEIAVRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBS9</accession>
    <name>A0A1Q2CBS9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00965</name>
        <name evidence="3" type="ORF">SAMN05428934_105144</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY87258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00965"/>
    <dbReference type="EnsemblBacteria" id="AQP43566">
        <property type="protein sequence ID" value="AQP43566"/>
        <property type="gene ID" value="RPIT_00965"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87258">
        <property type="protein sequence ID" value="SDY87258"/>
        <property type="gene ID" value="SAMN05428934_105144"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00965"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43566.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
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            <dbReference type="EMBL" id="SDY87258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="457" mass="48565" checksum="5526F2E7062C8A3A" modified="2017-04-12" version="1">MGDGIELISDGEGLAVIGSADDVERFLLDQGLNPAQSTALDVRRLGPIIGAGDAAARIGSDFAANSGRWVKLTAESAEAVKQYGLMDTCTPGVSHAMIGKRGDIQQWLQIVKGPGTFLTGPLALAALSTMMQQQAMQQQMDRIVEYLEEINEKVDDILRAQKDAVLSEMIGVDLIVEEALTVREQVGRVSEVTWSKVQATSMTIARTQGYALRQLDAIAEKLEKADDLGDLAKRTREAEPRVREWLTVLARTFQLLDGVSVLELDRVLDSSPEDLDSHRLGLAIARQNRRDLIARSTARILAQMSTTIGKANSKVLFNPFDSPAAVRASREVASGVVTFRDALGIESAHDDVDAKPWRSAAGEVLERVRTSGAEGAATVKRVGVEGIDRATGVFRPLDIDGDGVPDQPLAAAGIQRAGSAVKGAAGSAGGALSGLFKRKGSDAEPVDDSGNDSDANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBU9</accession>
    <name>A0A1Q2CBU9_9ACTN</name>
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        <submittedName>
            <fullName evidence="5">Right handed beta helix region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_01085</name>
        <name evidence="5" type="ORF">SAMN05428934_105168</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43586">
        <property type="protein sequence ID" value="AQP43586"/>
        <property type="gene ID" value="RPIT_01085"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87946">
        <property type="protein sequence ID" value="SDY87946"/>
        <property type="gene ID" value="SAMN05428934_105168"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01085"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
        <property type="entry name" value="Beta_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544394" evidence="2">
        <location>
            <begin position="25"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="Beta_helix" evidence="3">
        <location>
            <begin position="203"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY87946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="432" mass="42818" checksum="E980AA94FBD19256" modified="2017-04-12" version="1">MRAGSVAAALMCAVLAACSTPTEAPSTPAPATTETTAAGPTPWATDRCRELADGVGAALQAVVDSYEQPAPSPAPGSDGDDLEGSLATVQEAVEEGHCAPQTMQGWVEASVDAVKAEGTIAEAVRARLVAGLDGRIPTELVHVPVAPGEDLATAVSEAPSGATLQLAAGTFDLAEPLVLLGGITIAGAGQDETVLRSSAEDTAVLIATSETVSLEGLTIERDDTVTGSGIVAGGAASLVLEAVTVSGAVAGDTGGGAAVMLMGTQEGAERKTTAEITDSTLSGNDWAGLAVSGTHRVSVKSSTFADNGECGVCFLGESDGSVADSWMDANPVGVAMAEQSTPTLIGNAITGGEVGLQVQDDAAPIAEKNIITNPERAAVIVSGKAAGAFAENVCADVEFGIVVTDTAAPTLTHNECALARGQTESASPSPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBV6</accession>
    <name>A0A1Q2CBV6_9ACTN</name>
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        <submittedName>
            <fullName evidence="4">Uncharacterized membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01100</name>
        <name evidence="4" type="ORF">SAMN05428934_105171</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY88014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43589">
        <property type="protein sequence ID" value="AQP43589"/>
        <property type="gene ID" value="RPIT_01100"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY88014"/>
        <property type="gene ID" value="SAMN05428934_105171"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
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            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY88014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="163" mass="18000" checksum="3CFE37C4B8611DF8" modified="2017-04-12" version="1">MADHTAPASHSRDTSDGDRTRLGRLARGVGRWALGFALLGAGTGHLTTLRQEFQAQVPPWIPLDPDVVVVASGVVELGLGAALIFAPRRWWPWVGWTTAAFFVAIFPGNISQYVTGTDGFGLDTDRARFIRLFFQPVLVAWALWSTGAWRDRRSLGLGRRKDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBW8</accession>
    <name>A0A1Q2CBW8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Predicted dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01260</name>
        <name evidence="3" type="ORF">SAMN05428934_1081</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ00900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01260"/>
    <dbReference type="EnsemblBacteria" id="AQP43613">
        <property type="protein sequence ID" value="AQP43613"/>
        <property type="gene ID" value="RPIT_01260"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ00900">
        <property type="protein sequence ID" value="SDZ00900"/>
        <property type="gene ID" value="SAMN05428934_1081"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01260"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="18"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ00900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="340" mass="36864" checksum="38124723A24BB0AD" modified="2017-04-12" version="1">MTTLPTPRIPDPMDAPPLRWGILGTGWIAERFIDTLHKNTRQRLVAVGSRTESRGKRFADRFEAERAYGSYEALVEDADVDIVYVATPHSEHRDNALMAIEAGKPVLVEKAFARTFAEANEIVEAAGAAGVALMEAMWTRFLPHMDVVRQLLEVGALGEIETVFADHGQWFEQNESSRLFAPELAGGAMLDLGVYPVSFVNFVLGAPALAAALGSRAFTGVDRQISAVLGEFPDHPHAQALISTTLAARTPTVAHISGDKARIEIPGPFYGPGQISFITRDGEVAVSERPQIEDHGGLCYEAAHFATMVAEGRTESELMPHDDTLAVMATMDELVEEGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBY7</accession>
    <name>A0A1Q2CBY7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative Holin-X, holin superfamily III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01390</name>
        <name evidence="3" type="ORF">SAMN05428934_10826</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43633">
        <property type="protein sequence ID" value="AQP43633"/>
        <property type="gene ID" value="RPIT_01390"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01403">
        <property type="protein sequence ID" value="SDZ01403"/>
        <property type="gene ID" value="SAMN05428934_10826"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01390"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009937">
        <property type="entry name" value="Phage_holin_3_6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07332">
        <property type="entry name" value="Phage_holin_3_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ01403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="164" mass="17457" checksum="752AFD172B3BB38A" modified="2017-04-12" version="1">MPIEPRHTLVDIKDAISEFVSKESELAAAEIKPAAKAAGIGSGLFAGAAVFLFHVVWMLVIIIALAVGLLLNALTSLQPWTAITLGFVASMLFSLIVAVVLFIMGKGKFKQVKKPDATIAEAKATIDAVTNAVAARKPHAEVVVRADDLPQFRDADLHNTFGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC43</accession>
    <name>A0A1Q2CC43_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Pyrroline-5-carboxylate reductase</fullName>
            <shortName evidence="2">P5C reductase</shortName>
            <shortName evidence="2">P5CR</shortName>
            <ecNumber evidence="2 3">1.5.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">PCA reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">proC</name>
        <name evidence="6" type="ORF">RPIT_01685</name>
        <name evidence="7" type="ORF">SAMN05428934_10886</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-proline + NAD(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:14105"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15893"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>L-proline + NADP(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:14109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15893"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 3">Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.2" evidence="2 3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01685"/>
    <dbReference type="EnsemblBacteria" id="AQP43679">
        <property type="protein sequence ID" value="AQP43679"/>
        <property type="gene ID" value="RPIT_01685"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02551">
        <property type="protein sequence ID" value="SDZ02551"/>
        <property type="gene ID" value="SAMN05428934_10886"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01685"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00361"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PTHR11645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00521">
        <property type="entry name" value="P5CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0521">NADP</keyword>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 3" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_oxidored" evidence="4">
        <location>
            <begin position="2"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="P5CR_dimer" evidence="5">
        <location>
            <begin position="157"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ02551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="262" mass="26910" checksum="1536710E5DEBF6E4" modified="2017-04-12" version="1">MRIALVGAGAMGEALLAGWLAAGWSTEDVVIVEPSQQRADDITARHGVRAVDLEEASGADVVVLAVKPHQVESVLGSISNRLGPESVVVSIAAGVPIRQLEELLPDGAAVIRVMPNTPALVGQGMAGVVRGTAATDGHLATVQGLMDAVGRSTVIEEKYLDALTSVSGSGPAYLFYVADAMIEAGVHQGLTRAEATELTVQTFVGSAAMLATGRAAATLREQVTSPAGTTAAALRVLDERGVRAAFLAAMEACVTRSREMAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC50</accession>
    <name>A0A1Q2CC50_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mycothione reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_01740</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="7">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01740"/>
    <dbReference type="EnsemblBacteria" id="AQP43688">
        <property type="protein sequence ID" value="AQP43688"/>
        <property type="gene ID" value="RPIT_01740"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01740"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016668">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
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        <location>
            <begin position="5"/>
            <end position="322"/>
        </location>
    </feature>
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            <end position="453"/>
        </location>
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        </location>
    </feature>
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        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>FAD</name>
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        <location>
            <begin position="137"/>
            <end position="139"/>
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        <ligand>
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        </ligand>
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        </ligand>
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    <feature type="binding site" evidence="7">
        <location>
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        </location>
        <ligand>
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        </ligand>
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        <ligand>
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            <begin position="40"/>
            <end position="45"/>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP43688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="468" mass="51798" checksum="5DBACDA238FD3B2A" modified="2017-04-12" version="1">MQHFDLAVIGSGTGNSLIDERFADWNVALIERDETFGGTCLNRGCIPTKMFVVPADFAASPPHAKRLGVHLEHRGSDWNAIRDRIFGRIDPISEGGLDWRQRSSNVTVFTGEASFVDAQTLQIGDDRISADNIVIATGSRPRDLHVPGFEDVADRIYTSDTIMRIPDRPRRLMILGGGFIAAEFAHVFAALGTDVTLLNRSEVLLRGQDREVSEQFAALIGRRVRVRLNQKVSSVEKGSKGDIVVVTTDRNGVEYEYFTDAILVAVGRERNWEALNLSAAGIDVNVDGQIRVDAHQRTNVQGIWAMGDVSSDYLLKHVANAEMRTVQHNLLHPDDPVETDHRYVPSAVFSDPQIASVGATEEQLKAWGNPYVVARQRYADVAYGWALEDEGHFVKLLADPRSWHILGAHIVGPQASTLLQPLIQAMSFGQRVDDLARGQYWIHPSLPEVVENALLGLLAAHRPAELDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC79</accession>
    <name>A0A1Q2CC79_9ACTN</name>
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        <submittedName>
            <fullName evidence="4">Long-chain acyl-CoA synthetase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Long-chain fatty acid--CoA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01950</name>
        <name evidence="4" type="ORF">SAMN05428934_11614</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ20375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01950"/>
    <dbReference type="EnsemblBacteria" id="AQP43723">
        <property type="protein sequence ID" value="AQP43723"/>
        <property type="gene ID" value="RPIT_01950"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ20375">
        <property type="protein sequence ID" value="SDZ20375"/>
        <property type="gene ID" value="SAMN05428934_11614"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01950"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ANL_N_sf"/>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="31"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="466"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ20375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="551" mass="59808" checksum="D2155EE1FABEE9F1" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCA2</accession>
    <name>A0A1Q2CCA2_9ACTN</name>
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        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_02010</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S8 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP43734">
        <property type="protein sequence ID" value="AQP43734"/>
        <property type="gene ID" value="RPIT_02010"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Fn3_5"/>
    </dbReference>
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        <property type="entry name" value="PA_domain"/>
    </dbReference>
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        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
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        <property type="entry name" value="Peptidase_S8_His-AS"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF06280">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010365072" evidence="8">
        <location>
            <begin position="24"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="9">
        <location>
            <begin position="167"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="10">
        <location>
            <begin position="387"/>
            <end position="471"/>
        </location>
    </feature>
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        <location>
            <begin position="620"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="882"/>
            <end position="914"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP43734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="914" mass="93439" checksum="C9C9FC283B5D4461" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCL1</accession>
    <name>A0A1Q2CCL1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_02730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02730"/>
    <dbReference type="EnsemblBacteria" id="AQP43863">
        <property type="protein sequence ID" value="AQP43863"/>
        <property type="gene ID" value="RPIT_02730"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="144"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="426"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="590" mass="65359" checksum="3D4AE5E3983EE6CE" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCQ9</accession>
    <name>A0A1Q2CCQ9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">ABC-type multidrug transport system, ATPase and permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_02840</name>
        <name evidence="11" type="ORF">SAMN05428934_101168</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY27219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02840"/>
    <dbReference type="EnsemblBacteria" id="AQP43881">
        <property type="protein sequence ID" value="AQP43881"/>
        <property type="gene ID" value="RPIT_02840"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY27219">
        <property type="protein sequence ID" value="SDY27219"/>
        <property type="gene ID" value="SAMN05428934_101168"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02840"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="266"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="46"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="363"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="396"/>
            <end position="403"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP43881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY27219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="603" mass="65746" checksum="B73FC0CD82B6ADB0" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCR3</accession>
    <name>A0A1Q2CCR3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA-directed RNA polymerase subunit beta'</fullName>
            <shortName evidence="7">RNAP subunit beta'</shortName>
            <ecNumber evidence="7">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">RNA polymerase subunit beta'</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Transcriptase subunit beta'</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpoC</name>
        <name evidence="11" type="ORF">RPIT_02920</name>
        <name evidence="12" type="ORF">SAMN05428934_101185</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7 8">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY27777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02920"/>
    <dbReference type="EnsemblBacteria" id="AQP43894">
        <property type="protein sequence ID" value="AQP43894"/>
        <property type="gene ID" value="RPIT_02920"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY27777">
        <property type="protein sequence ID" value="SDY27777"/>
        <property type="gene ID" value="SAMN05428934_101185"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02920"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01322">
        <property type="entry name" value="RNApol_bact_RpoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012754">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
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    </dbReference>
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        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02386">
        <property type="entry name" value="rpoC_TIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 7 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
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    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RPOLA_N" evidence="10">
        <location>
            <begin position="310"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="160"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
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        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="535"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="537"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="539"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
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        <location>
            <position position="871"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
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        <location>
            <position position="967"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
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        <location>
            <position position="974"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
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        <location>
            <position position="977"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP43894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY27777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="1312" mass="145953" checksum="91DA8344EA457947" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCT6</accession>
    <name>A0A1Q2CCT6_9ACTN</name>
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        <recommendedName>
            <fullName evidence="2">Thiosulfate sulfurtransferase</fullName>
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        </recommendedName>
    </protein>
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        <name evidence="4" type="ORF">RPIT_03110</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>hydrogen cyanide + thiosulfate = 2 H(+) + sulfite + thiocyanate</text>
            <dbReference type="Rhea" id="RHEA:16881"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:18022"/>
            <dbReference type="ChEBI" id="CHEBI:18407"/>
            <dbReference type="ChEBI" id="CHEBI:33542"/>
            <dbReference type="EC" id="2.8.1.1"/>
        </reaction>
    </comment>
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        <property type="protein sequence ID" value="AQP43928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43928">
        <property type="protein sequence ID" value="AQP43928"/>
        <property type="gene ID" value="RPIT_03110"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03110"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Rhodanese-like_dom"/>
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    </dbReference>
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        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="13"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="103" mass="10829" checksum="A221C13381CA0780" modified="2017-04-12" version="1">MREVDIPTLRAALDQGAFLLDVREPHEYEEVHVPGAVLIPLGQVADRVDELPEDVWVICRSGVRSLKGAEAVAASGRSACSVAGGTLAWIDAGLPVATGTQPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD98</accession>
    <name>A0A1Q2CD98_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Transcriptional regulator, TraR/DksA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_04065</name>
        <name evidence="9" type="ORF">SAMN05428934_101416</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY34551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04065"/>
    <dbReference type="EnsemblBacteria" id="AQP44089">
        <property type="protein sequence ID" value="AQP44089"/>
        <property type="gene ID" value="RPIT_04065"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY34551">
        <property type="protein sequence ID" value="SDY34551"/>
        <property type="gene ID" value="SAMN05428934_101416"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04065"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037187">
        <property type="entry name" value="DnaK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000962">
        <property type="entry name" value="Znf_DskA_TraR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020458">
        <property type="entry name" value="Znf_DskA_TraR_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01258">
        <property type="entry name" value="zf-dskA_traR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109635">
        <property type="entry name" value="SSF109635"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01102">
        <property type="entry name" value="ZF_DKSA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51128">
        <property type="entry name" value="ZF_DKSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DksA C4-type" evidence="7">
        <location>
            <begin position="68"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="dksA C4-type" evidence="4">
        <location>
            <begin position="111"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="26"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY34551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="142" mass="15709" checksum="656528F0F7423D17" modified="2017-04-12" version="1">MPTSKKATAPEAVALPVLEGEEPWTAEEVAEQRAELKDELERLERRIAQTEAELAAILRGGTDGAGRDPADVGSSNFERDQELSLAQNVRDMAEQLRLAIHLFDKGEYGLCESCGQPIGKGRLQVFPRATMCVACKQREERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDD5</accession>
    <name>A0A1Q2CDD5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoprotein signal peptidase</fullName>
            <ecNumber evidence="6">3.4.23.36</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Prolipoprotein signal peptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Signal peptidase II</fullName>
            <shortName evidence="6">SPase II</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lspA</name>
        <name evidence="8" type="ORF">RPIT_04070</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This protein specifically catalyzes the removal of signal peptides from prolipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Release of signal peptides from bacterial membrane prolipoproteins. Hydrolyzes -Xaa-Yaa-Zaa-|-(S,diacylglyceryl)Cys-, in which Xaa is hydrophobic (preferably Leu), and Yaa (Ala or Ser) and Zaa (Gly or Ala) have small, neutral side chains.</text>
            <dbReference type="EC" id="3.4.23.36"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; lipoprotein biosynthesis (signal peptide cleavage).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the peptidase A8 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.36" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04070"/>
    <dbReference type="EnsemblBacteria" id="AQP44090">
        <property type="protein sequence ID" value="AQP44090"/>
        <property type="gene ID" value="RPIT_04070"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04070"/>
    <dbReference type="UniPathway" id="UPA00665"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00161">
        <property type="entry name" value="LspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001872">
        <property type="entry name" value="Peptidase_A8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33695">
        <property type="entry name" value="PTHR33695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01252">
        <property type="entry name" value="Peptidase_A8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00781">
        <property type="entry name" value="LIPOSIGPTASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00077">
        <property type="entry name" value="lspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="178" mass="18960" checksum="D08D0965D678DFF7" modified="2017-04-12" version="1">MQAARGTTLSVRHRGVGLIAFGIGVFGLGLDQTVKKISLAQLEPGEPINLVGDLFRLNLIWNPGAAFGMGADATIFFTIFAIIATVACLVVGLPRITRLWHAIALGMLLAGITGNLVDRFTQPPSPLRGHVVDMFQLKYFAIFNVADVFITAAAALILLGSFFPDEAADEPAEERAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDD6</accession>
    <name>A0A1Q2CDD6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03905</name>
        <name evidence="3" type="ORF">SAMN05428934_101385</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY33699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44065">
        <property type="protein sequence ID" value="AQP44065"/>
        <property type="gene ID" value="RPIT_03905"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY33699">
        <property type="protein sequence ID" value="SDY33699"/>
        <property type="gene ID" value="SAMN05428934_101385"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03905"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="163"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY33699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="371" mass="40434" checksum="4D750E2EE1453E45" modified="2017-04-12" version="1">MRQLVDALLDPVILAELTGRTVVADRIRIKAKNSVVLALRDAETGQPDGWARVLWPITQDKASKVVERAQRRGQRIQTRPLHAGLMMQWGELASDPQLAAVYRVALKEGLIEAGDQVLRYNPLRRLVVRHGDTTVRLSTQANPVALPLDWALIEDGVPLPGRLDSGAHPQIAVQRFVGDTDLEDTRDLAATRTVGAALATLHRAEVPNALRGWLSSREPDPREQGAAHVELLSLLDDDLAARMASLADQTARRWDQVRTDTRLVVHGDASPDQMLLDSATGRVWVTDLERACLADPAVDLGSYLANCSDDEGAALLAGYTAAGGALPASRLLDAARSRAILLAAADPIRRAEPEWREHVSQRLDALEGTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDF7</accession>
    <name>A0A1Q2CDF7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04290"/>
    <dbReference type="EnsemblBacteria" id="AQP44127">
        <property type="protein sequence ID" value="AQP44127"/>
        <property type="gene ID" value="RPIT_04290"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04290"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="211" mass="23467" checksum="38353C0DE60AE8CD" modified="2017-04-12" version="1">MTDIEMMAWLGAGYGVLLLLVAYGIDQLAKRAQTRIEEDRAGGFVYHENHDAWLCPEDQWLYPKSFDPDNRVMRYRGLPLVCNSCPVKDTCTASDDGREMKRHVDPWPASESARFHRGIACSVTVLAVLWPALTALMVTSWTSQVLALATAFLIALGALPLWAHLRRTPADPLGAVVRTLDQTMEDRQAAAAAITRARTSYASDRRIDHAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDH0</accession>
    <name>A0A1Q2CDH0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 9">Enoyl-[acyl-carrier-protein] reductase [NADH]</fullName>
            <ecNumber evidence="9">1.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_04435</name>
        <name evidence="13" type="ORF">SAMN05428934_101493</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 2,3-saturated acyl-CoA + NAD(+) = a (2E)-enoyl-CoA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:18177"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="ChEBI" id="CHEBI:65111"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="2">
            <dbReference type="Rhea" id="RHEA:18179"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2,3-saturated acyl-[ACP] + NAD(+) = a (2E)-enoyl-[ACP] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:10240"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9926"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78785"/>
            <dbReference type="EC" id="1.3.1.9"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="1">
            <dbReference type="Rhea" id="RHEA:10242"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; mycolic acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.9" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY36733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04435"/>
    <dbReference type="EnsemblBacteria" id="AQP44154">
        <property type="protein sequence ID" value="AQP44154"/>
        <property type="gene ID" value="RPIT_04435"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY36733">
        <property type="protein sequence ID" value="SDY36733"/>
        <property type="gene ID" value="SAMN05428934_101493"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04435"/>
    <dbReference type="UniPathway" id="UPA00915"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004318">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016631">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014358">
        <property type="entry name" value="Enoyl-ACP_Rdtase_NADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43159">
        <property type="entry name" value="PTHR43159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000094">
        <property type="entry name" value="Enoyl-ACP_rdct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 9 11" id="KW-0520">NAD</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="11">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="19"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="192"/>
            <end position="196"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP44154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY36733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="257" mass="26891" checksum="20314C5995CCCD20" modified="2017-04-12" version="1">MGLLEGKNILVTGVTMRTSIAYAVVDIAQREGATVVVSAAGRAVAPAQRAISKLETVPPLIELDITDPEHLAELPERLGVLIDGGLDGIVHSIAYADPEKALGGAFLTTDWETVGNALHISAYSLQSLTMAAKPLLNRGSSVVGLTFDARVSWPSYDWMGVAKAALESTSRYLARYLGPDGIRCNLVAAGPVDTVAKKAIPGASSFNDIWAERAPLSWDSSDAVPSAKAVVALLSDWFPATTGEMVHVDGGLHSTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDI5</accession>
    <name>A0A1Q2CDI5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Tyrosine recombinase XerC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">xerC</name>
        <name evidence="13" type="ORF">RPIT_04485</name>
        <name evidence="14" type="ORF">SAMN05428934_101503</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the 'phage' integrase family. XerC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY36979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04485"/>
    <dbReference type="EnsemblBacteria" id="AQP44161">
        <property type="protein sequence ID" value="AQP44161"/>
        <property type="gene ID" value="RPIT_04485"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY36979">
        <property type="protein sequence ID" value="SDY36979"/>
        <property type="gene ID" value="SAMN05428934_101503"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04485"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009037">
        <property type="term" value="F:tyrosine-based site-specific recombinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01808">
        <property type="entry name" value="Recomb_XerC_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023009">
        <property type="entry name" value="Tyrosine_recombinase_XerC/XerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="4 9" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0229">DNA integration</keyword>
    <keyword evidence="7 9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="12">
        <location>
            <begin position="5"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="11">
        <location>
            <begin position="108"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="273"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="9">
        <location>
            <position position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP44161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY36979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="301" mass="32601" checksum="2843DDB6AEADCC05" modified="2017-04-12" version="1">MDLPPGWDGVLDDYGAHLGRERGLSEHTVRAYLADLRGLARHADVAPQRVTLSRLRSWLAWLGDEGASSATIQRRVASVRGFFTWADREGFVTPNPSLRLKAPRKTRRLPHVPTATAVATTLGSAEARATEEGDPEALRDLALVELLYSCGLRVSEACALTMRQIDRDRRSVTVVGKGGKERVVPLGLPALRALDAWLLVRPTIATDRSPDTVFLGVQGGPLDPRVARRVVHSATAAAGPGAEVGPHGLRHAMATHLIEGGADLRSVQEMLGHSSVATTQLYTHVTSERLRQAFRDAHPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDL5</accession>
    <name>A0A1Q2CDL5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Kanamycin kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_04530</name>
        <name evidence="7" type="ORF">SAMN05428934_101512</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aminoglycoside phosphotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04530"/>
    <dbReference type="EnsemblBacteria" id="AQP44170">
        <property type="protein sequence ID" value="AQP44170"/>
        <property type="gene ID" value="RPIT_04530"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37194">
        <property type="protein sequence ID" value="SDY37194"/>
        <property type="gene ID" value="SAMN05428934_101512"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04530"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024165">
        <property type="entry name" value="Kan/Strep_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000706">
        <property type="entry name" value="Kanamycin_kin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="5">
        <location>
            <begin position="155"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000706-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000706-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY37194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="238" mass="26042" checksum="A9921AF0BBA6D9B2" modified="2017-04-12" version="1">MIVGMTLTSAPPPGTPVPFAITHWAAAHGRRVAELVWRNEAGGITARLVADDTKDLYAKWSPDDLEPEAERLSWLSSRHPSPRMFDYEETDDGWLIVTGALVGSNAVSPRWKADPQRAAFAIGEGYARLHSLDPDDCPFGTPDWIGVQDDIDVLVVVHGDACAPNTILTDEGAFAGHVDMGELGVADRWADLAIASWSLEWNFGSGLDDAFWRGYGEAPDPERIRRYRTLWGEAPTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDM9</accession>
    <name>A0A1Q2CDM9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Iron ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_04440</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04440"/>
    <dbReference type="EnsemblBacteria" id="AQP44155">
        <property type="protein sequence ID" value="AQP44155"/>
        <property type="gene ID" value="RPIT_04440"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04440"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="262" mass="28451" checksum="6F3D695ABDEEFEDB" modified="2017-04-12" version="1">MASVAELAGVTIRRGNAVLLDQISLVIREEERWVVIGPNGAGKTTLLQLLSAQLYPTDGVVGVLGEVVGAVDVFELRPRIGLTSSALAERIPHDEKVRDVVLSAAYAVVGRWREEYDDYDVEQAERLLGSLRVQRLAERTFGTLSEGERKRVQIARALMTDPELLLLDEPAGGLDLAGREALVDTLSELCTDPDSPATVLVTHHVEEIPEGITHCLLLNSGRVVAAGPLADTLTDENLSRTFDMPLSVGQVEGRWSARSRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDP8</accession>
    <name>A0A1Q2CDP8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Gamma-glutamyl phosphate reductase</fullName>
            <shortName evidence="7">GPR</shortName>
            <ecNumber evidence="7">1.2.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamate-5-semialdehyde dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glutamyl-gamma-semialdehyde dehydrogenase</fullName>
            <shortName evidence="7">GSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">proA</name>
        <name evidence="9" type="ORF">RPIT_04690</name>
        <name evidence="10" type="ORF">SAMN05428934_101545</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19541"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the gamma-glutamyl phosphate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.41" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04690"/>
    <dbReference type="EnsemblBacteria" id="AQP44200">
        <property type="protein sequence ID" value="AQP44200"/>
        <property type="gene ID" value="RPIT_04690"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37977">
        <property type="protein sequence ID" value="SDY37977"/>
        <property type="gene ID" value="SAMN05428934_101545"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04690"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004350">
        <property type="term" value="F:glutamate-5-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07079">
        <property type="entry name" value="ALDH_F18-19_ProA-GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00412">
        <property type="entry name" value="ProA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020593">
        <property type="entry name" value="G-glutamylP_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012134">
        <property type="entry name" value="Glu-5-SA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000965">
        <property type="entry name" value="GPR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000151">
        <property type="entry name" value="GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00407">
        <property type="entry name" value="proA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01223">
        <property type="entry name" value="PROA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0521">NADP</keyword>
    <keyword evidence="6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="9"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY37977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="413" mass="43247" checksum="11CFF9DF337ACDC1" modified="2017-04-12" version="1">MEFRDQAIAARAAAVELATLRRSQKDAALNAMADSLAAAESELLEANAVDVARAREAGTEESIVDRLSLNPDRIRGMVQGLRDLAALPDPVGDVVRGWKLGNGVSVTQVRVPFGVVGIIYEARPNVTADAAGICLKSGNAALLRGSSSALQTNRVTVEALRRGLKDAGVTEDAVHLIEGDRDATTELMRARGLVDVLIPRGGAGLIQAVVDGSTVPVIETGTGNCHIYVDADADVDQALAILLNAKTQRPSVCNAAETLLVHSAAAPDFLPRALSALRQAGVTVHGDSATAGYGEGVVPARPDEYDAEYLTLDLAAKVVGSMDEALQHIREHTTGHSETIVTRSRSAADRFVAEVDAAAVLVNASSRFVDGGEFGFGAEIGISTQKLHARGPMGLQEMTSSKYVVEGDGQVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDQ9</accession>
    <name>A0A1Q2CDQ9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphate starvation-inducible protein PhoH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_04995</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04995"/>
    <dbReference type="EnsemblBacteria" id="AQP44249">
        <property type="protein sequence ID" value="AQP44249"/>
        <property type="gene ID" value="RPIT_04995"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04995"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003714">
        <property type="entry name" value="PhoH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02562">
        <property type="entry name" value="PhoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoH" evidence="3">
        <location>
            <begin position="116"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="335" mass="36689" checksum="BCFE0D6B0FB76C1B" modified="2017-04-12" version="1">MKNNTLDQQHATRIVSVPSSIDMVNILGPRDDYLRILEDQLDADLHVRGGQITVSGPSREVSKAAEVLIELITIVRTGQGLTGETVERVIQMADDPSTSASEILTQNIVSARGKTVRPKTLNQKRYVDAIDRHTVVFGIGPAGTGKTYLAMAKAVQALQAKEVSRIILTRPAIEAGERLGFLPGTLNDKIDPYLRPLYDALHDMVDADSVPKLLTSGTVEVAPLAYMRGRTLNDAFIILDEAQNTSMEQMKMFLTRLGFGSKVVVTGDVTQIDLPGGVKSGLRGVQQILDGVDDIEFCTLTSRDVVRHKLVGRIVAAYDQFESLSTERHERRAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDR7</accession>
    <name>A0A1Q2CDR7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05080</name>
        <name evidence="3" type="ORF">SAMN05428934_101622</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY39964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05080"/>
    <dbReference type="EnsemblBacteria" id="AQP44264">
        <property type="protein sequence ID" value="AQP44264"/>
        <property type="gene ID" value="RPIT_05080"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY39964">
        <property type="protein sequence ID" value="SDY39964"/>
        <property type="gene ID" value="SAMN05428934_101622"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05080"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="18"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY39964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="99" mass="11031" checksum="2BE09A350BE3D6F8" modified="2017-04-12" version="1">MLVINRFANQDPSFAVEAREVVSWWSGRPGCLGIDVVQNLDDPRLWALVGRWESVGDYRRSFNGYEAKMVLTPLLSRAVDEPSAFLPPDEVGVNLPRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDV2</accession>
    <name>A0A1Q2CDV2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">MoxR-like ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05160</name>
        <name evidence="4" type="ORF">SAMN05428934_101638</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY40382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05160"/>
    <dbReference type="EnsemblBacteria" id="AQP44277">
        <property type="protein sequence ID" value="AQP44277"/>
        <property type="gene ID" value="RPIT_05160"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY40382">
        <property type="protein sequence ID" value="SDY40382"/>
        <property type="gene ID" value="SAMN05428934_101638"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05160"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="52"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="259"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY40382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="354" mass="38276" checksum="52F18AE5B9A59ED2" modified="2017-04-12" version="1">MSTTPIEEQPLPGGVADAAQLLGKAISQVQRVIVGQEHMVQQLMVALLAKGHCLLEGVPGVAKTLAVRSFATVVGGDFARVQFTPDLVPSDIVGTRIYSAKSETFEIELGPVFVNFVLADEINRAPAKVQSAMLELMAEKQVSIGGVTYPAPKPFIVIATQNPIESEGVYPLPEAQRDRFLVKVDVPYPRGNEELEILRRMSVSPPEAERVLNPSLVRHLQDMASNVFVHNLVAEYIVRLVLASRTPSEFGMPDLEGVIQIGCSPRATLGLVAAARALALINGRDYVLPTDVQAVAKDVMSHRIVLGFDAVADNVSTADVVERILAMVPAPTPVWNEQQRQASHEAHAHQPGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDX2</accession>
    <name>A0A1Q2CDX2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_05335</name>
        <name evidence="10" type="ORF">SAMN05428934_10314</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY65378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05335"/>
    <dbReference type="EnsemblBacteria" id="AQP44306">
        <property type="protein sequence ID" value="AQP44306"/>
        <property type="gene ID" value="RPIT_05335"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY65378">
        <property type="protein sequence ID" value="SDY65378"/>
        <property type="gene ID" value="SAMN05428934_10314"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05335"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="190"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="257"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="472"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY65378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="497" mass="53645" checksum="8E09EB3059F30021" modified="2017-04-12" version="1">MLISTLGLSIVVLGLAGLVLLQQATAGVVASKRDASLNEAAGVYAFMQAQLRTPEERGVAVHESLNRLADLADAQTTQYRVVIQGPTSSLVSAGIRAESVPTELRERVELGEGMFITPTEVVYSDPAAVAEPGWAIGTSLIGATGERYPIYYIFPMTAEQQTLGVLQRAVVGTGLALLAALGLISYLVTVQVVRPVRRASQTALKLASGELGERVAVRGTDDLASLAKSMNRMAAQLQQRFRELETLSTLQQRFVSDVSHELRTPMTTIKMASDVLHEGRGTFDPLTARTAELMSLEIDRFDAMLADLLEISRFDAGAAVLALDETDVGALVEAEINANRRMAEKLGVEVTVDVRTQDNQAAVDSRRIRRILRNLITNAIEHAEGKPVRVTVAADDVSVAVTVRDYGVGFEADDAPHVFDRFWRADPSRTRVVGGSGLGLAIAMEDARLHRGWLTAWGRPGRGAQFRLTVPRDPDHELTGSPLPVAPDDDVPAEVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE03</accession>
    <name>A0A1Q2CE03_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_05455</name>
        <name evidence="2" type="ORF">SAMN05428934_10338</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY66094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05455"/>
    <dbReference type="EnsemblBacteria" id="AQP44327">
        <property type="protein sequence ID" value="AQP44327"/>
        <property type="gene ID" value="RPIT_05455"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY66094">
        <property type="protein sequence ID" value="SDY66094"/>
        <property type="gene ID" value="SAMN05428934_10338"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05455"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY66094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="65" mass="7365" checksum="3329824CFCCA87A8" modified="2017-04-12" version="1">MMTELAADPTLTAIDRCDRCGAQAYLRVFLRSGGELLFCAHHARAHREKLVEVASRIQDETHKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE27</accession>
    <name>A0A1Q2CE27_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Two-component system, OmpR family, response regulator MtrA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_05330</name>
        <name evidence="7" type="ORF">SAMN05428934_10313</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY65346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05330"/>
    <dbReference type="EnsemblBacteria" id="AQP44305">
        <property type="protein sequence ID" value="AQP44305"/>
        <property type="gene ID" value="RPIT_05330"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY65346">
        <property type="protein sequence ID" value="SDY65346"/>
        <property type="gene ID" value="SAMN05428934_10313"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05330"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="9"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="131"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="131"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY65346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="233" mass="25588" checksum="6A642E03C0258176" modified="2017-04-12" version="1">MSEARAKSRILVIDDDAALSEMLQIVLRQEGYETVRCATGSAAMAEFRQSKPDLVLLDLMLPGRDGVAVCRDIRAESGVPIVMLTAKSDTSDVVAGLEAGADDYVAKPFKAKELIARIRTRLRRNGGDVGTDVLSIGDLTISVSSHVVKRDQQTLALTPLEFDLLLALAKRPTHVFTREALLDEVWGYRNAADTRLVNVHVQRLRAKVEKDPEKPEIVITVRGIGYRAGEPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE51</accession>
    <name>A0A1Q2CE51_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Trk system potassium uptake protein TrkA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_05590</name>
        <name evidence="8" type="ORF">SAMN05428934_10365</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY66827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05590"/>
    <dbReference type="EnsemblBacteria" id="AQP44350">
        <property type="protein sequence ID" value="AQP44350"/>
        <property type="gene ID" value="RPIT_05590"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY66827">
        <property type="protein sequence ID" value="SDY66827"/>
        <property type="gene ID" value="SAMN05428934_10365"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05590"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006036">
        <property type="entry name" value="K_uptake_TrkA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00335">
        <property type="entry name" value="KUPTAKETRKA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0630">Potassium</keyword>
    <keyword evidence="2" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="5">
        <location>
            <begin position="2"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="6">
        <location>
            <begin position="137"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00017378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY66827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="226" mass="24372" checksum="2D906B39E5AC482C" modified="2017-04-12" version="1">MRVAIAGAGNVGRSIARELIANGHHVILIERDPRAIKPDSVPGAEWVQADACELQSLEDANLEQCDVAIAATGDDKANLVHSLLAKTEFGVPRTVGRVNHPGNEWMFDAAWGVDVSVSTPRLMSALVEEAVSTGDLVRLLTFNKSDTHLSEVTLPGDSTFVGRRLRDVELPADVVLVALIRDSIPLPPERDRAFEAGDELLFLVNQDSEADLAAMFASDDTVDPQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE59</accession>
    <name>A0A1Q2CE59_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sirohydrochlorin ferrochelatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_05640</name>
        <name evidence="2" type="ORF">SAMN05428934_10375</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05640"/>
    <dbReference type="EnsemblBacteria" id="AQP44360">
        <property type="protein sequence ID" value="AQP44360"/>
        <property type="gene ID" value="RPIT_05640"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67072">
        <property type="protein sequence ID" value="SDY67072"/>
        <property type="gene ID" value="SAMN05428934_10375"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05640"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY67072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="257" mass="26617" checksum="21E35044899C9AA5" modified="2017-04-12" version="1">MTAPAIVLVAAGPDEPAVSETLHTISASLQASRPDLRISLARLGDGKPALTDVIAGLVSRDVAEAVLIPLDLTSAATHPTTLDGIIHSPDIHLAVARPVGPATEVLNILDERVREALHRGGALEIDGLVLAAPQGGDVRGASLLARRARQWAAHHRLPVQLAVDDGTGRATASAISSLRSQGRRHIAVGSLFLTPSGSYQAHAQAALRAGAIAVTAPIGDSPHLRQLILARYAFGAMELLDGTPTQLPVDDLDSDDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE79</accession>
    <name>A0A1Q2CE79_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_05920</name>
        <name evidence="2" type="ORF">SAMN05428934_103131</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44408">
        <property type="protein sequence ID" value="AQP44408"/>
        <property type="gene ID" value="RPIT_05920"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68494">
        <property type="protein sequence ID" value="SDY68494"/>
        <property type="gene ID" value="SAMN05428934_103131"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05920"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY68494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="165" mass="18017" checksum="E21ED9BC0D84C92E" modified="2017-04-12" version="1">MVAEEVWYETLEQMAANSVAVVTFELLETEYGLVYPDWSSDDPMINPYAGTDFTPSREETAGRPGTFHHVRVVSVAAGDLSPGDEIVILEAGGEVDGVMYEAVGRPELTEVELLFLDATSEDRYVILGSQARFASDGEGGYRSLVSPELQITPDDLDELAELIHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEC6</accession>
    <name>A0A1Q2CEC6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Carbamoyl-phosphate synthase large chain</fullName>
            <ecNumber evidence="15">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Carbamoyl-phosphate synthetase ammonia chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15 19" type="primary">carB</name>
        <name evidence="19" type="ORF">RPIT_06180</name>
        <name evidence="20" type="ORF">SAMN05428934_103181</name>
    </gene>
    <organism evidence="19 21">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 21" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 21">RP1T</strain>
        </source>
    </reference>
    <reference evidence="20 22" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 22">RP1</strain>
        </source>
    </reference>
    <reference evidence="19" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="15">Binds 4 Mg(2+) or Mn(2+) ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="15">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the CarB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="15"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY69740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06180"/>
    <dbReference type="EnsemblBacteria" id="AQP44451">
        <property type="protein sequence ID" value="AQP44451"/>
        <property type="gene ID" value="RPIT_06180"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY69740">
        <property type="protein sequence ID" value="SDY69740"/>
        <property type="gene ID" value="SAMN05428934_103181"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06180"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00171"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01424">
        <property type="entry name" value="MGS_CPS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01210_B">
        <property type="entry name" value="CPSase_L_chain_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006275">
        <property type="entry name" value="CarbamoylP_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005480">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036897">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005483">
        <property type="entry name" value="CbamoylP_synth_lsu_CPSase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033937">
        <property type="entry name" value="MGS_CPS_CarB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02787">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00098">
        <property type="entry name" value="CPSASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01096">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48108">
        <property type="entry name" value="SSF48108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="SSF52335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01369">
        <property type="entry name" value="CPSaseII_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 15" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="11 15 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 15 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13 15" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 15" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-grasp" evidence="17">
        <location>
            <begin position="139"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="17">
        <location>
            <begin position="683"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="domain" description="MGS-like" evidence="18">
        <location>
            <begin position="956"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carboxyphosphate synthetic domain" evidence="15">
        <location>
            <begin position="1"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Allosteric domain" evidence="15">
        <location>
            <begin position="956"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="833"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="845"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="847"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>4</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="AQP44451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="SDY69740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="1100" mass="117747" checksum="0E3E85CD323B7CD7" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEL1</accession>
    <name>A0A1Q2CEL1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Alpha-ketoglutarate decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">kgd</name>
        <name evidence="15" type="ORF">RPIT_06770</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + succinyl-CoA = (R)-N(6)-(S(8)-succinyldihydrolipoyl)-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + CoA</text>
            <dbReference type="Rhea" id="RHEA:15213"/>
            <dbReference type="Rhea" id="RHEA-COMP:10581"/>
            <dbReference type="Rhea" id="RHEA-COMP:10582"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83120"/>
            <dbReference type="EC" id="2.3.1.61"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>(R)-N(6)-lipoyl-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] + 2-oxoglutarate + H(+) = (R)-N(6)-(S(8)-succinyldihydrolipoyl)-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] + CO2</text>
            <dbReference type="Rhea" id="RHEA:12188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10483"/>
            <dbReference type="Rhea" id="RHEA-COMP:10484"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83120"/>
            <dbReference type="EC" id="1.2.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate metabolism; tricarboxylic acid cycle; succinyl-CoA from 2-oxoglutarate (dehydrogenase route): step 1/1.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06770"/>
    <dbReference type="EnsemblBacteria" id="AQP44554">
        <property type="protein sequence ID" value="AQP44554"/>
        <property type="gene ID" value="RPIT_06770"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06770"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00997"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004149">
        <property type="term" value="F:dihydrolipoyllysine-residue succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032106">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="PTHR23152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16078">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Transket_pyr" evidence="14">
        <location>
            <begin position="894"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="21"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="55"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="88"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="AQP44554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="1240" mass="137741" checksum="D71DFFFEEFDD6407" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEM1</accession>
    <name>A0A1Q2CEM1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_06870</name>
        <name evidence="2" type="ORF">SAMN05428934_11072</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06870"/>
    <dbReference type="EnsemblBacteria" id="AQP44569">
        <property type="protein sequence ID" value="AQP44569"/>
        <property type="gene ID" value="RPIT_06870"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09545">
        <property type="protein sequence ID" value="SDZ09545"/>
        <property type="gene ID" value="SAMN05428934_11072"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06870"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ09545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="442" mass="48994" checksum="C138F79A01F82820" modified="2017-04-12" version="1">MEIETRTPAEQLRACEALRRTAEARSLDILCELAEHYEVSEDSLIEHLVDRRIQPVVPGPTVSEFLSLELAGLLECTPLQAAAKLYSALRLKYRHPTLHTAVQQLDIEPHRALRAVDKCAHLDASVAERVTTGWLPQQLGLGHTAALNRLDKLVVEADPQRAIERERARRKDLDVSLWGSYDGVTTLSGRLEDLDARYLDASVDRMADVLTAEHPGLSRGQLRAKAMGVLANPAMALGLLQRAAQPALPDSEAPNGCLGPLCGTIQTPLHKLRPRLELAVHIDTNAVGCATGSARIEGAGHITLNLLREYLSDIDVTVQPVIDLATVAPEDQYRPSAALKKVLLLAFPTEMFPFSNRATARFMDFDHTERFRSGRRRQTRLGNLCPFSRRPHRGKTAGVWDVKQHSVGVLTWTSPLKYVYEVSPGGTRLVDTGHDAWRKLDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEN0</accession>
    <name>A0A1Q2CEN0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GMP synthase (Glutamine-hydrolysing)</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Glutamine amidotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06945</name>
        <name evidence="3" type="ORF">SAMN05428934_11056</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06945"/>
    <dbReference type="EnsemblBacteria" id="AQP44582">
        <property type="protein sequence ID" value="AQP44582"/>
        <property type="gene ID" value="RPIT_06945"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09207">
        <property type="protein sequence ID" value="SDZ09207"/>
        <property type="gene ID" value="SAMN05428934_11056"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06945"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01741">
        <property type="entry name" value="GATase1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044992">
        <property type="entry name" value="ChyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695">
        <property type="entry name" value="PTHR42695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="47"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ09207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="248" mass="26628" checksum="2A9AAF3869DD9626" modified="2017-04-12" version="1">MLPFLLLSTRPEDDAAEGERAAIVRLAGLRDDELIQHRVEAAPLGPINLDDYAGVFLGGGPFNASDEHKTDLQRRVEADVNRVVDDVVARDLPFLGLCYGVGVLTDRLGGVVDKTYPEAVGVSTSTLTEEGAADPLFAGVPATIRAFTGHKEACRELPPGAVLLASGEVSPVQAFRVGSHAYATQFHPELDSAGLAARIRIYRDAGYFRPEDTETLVDFALSAEITHDVHTVLRNFVALARQHSVNGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CET9</accession>
    <name>A0A1Q2CET9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ornithine aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ornithine--oxo-acid aminotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_07180</name>
        <name evidence="8" type="ORF">SAMN05428934_1108</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-ornithine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.13" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07180"/>
    <dbReference type="EnsemblBacteria" id="AQP44623">
        <property type="protein sequence ID" value="AQP44623"/>
        <property type="gene ID" value="RPIT_07180"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08132">
        <property type="protein sequence ID" value="SDZ08132"/>
        <property type="gene ID" value="SAMN05428934_1108"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07180"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00358"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050155">
        <property type="term" value="F:ornithine(lysine) transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004587">
        <property type="term" value="F:ornithine-oxo-acid transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010164">
        <property type="entry name" value="Orn_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986:SF18">
        <property type="entry name" value="PTHR11986:SF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01885">
        <property type="entry name" value="Orn_aminotrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ08132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="407" mass="42991" checksum="DE8426DD0EB2FC66" modified="2017-04-12" version="1">MSTTPSPEPTTTRLIQAESEHVARNYDPLPVVVATAEDVWVTDVEGRRYLDLLSAYSALNFGHRHPDLVKVAVDQIGRLTLTSRAFHNDRLGPFAAALAELCGKDMVLPMNTGAEAVETGIKAARAWAHRVKGVPDEAAQIVVAEGNFHGRTTTIVGFSDDPVTREGFGPFTPGFVTVPYQDVAAIEAAINDHTAAVLIEPIQGEGGVIIPPPGYLRAVRELCTEHNVLLIADEIQSGLGRAGTTFACDREGVVPDLYLLGKALGGGIVPVSAVVGNREVLGVFRPGEHGSTFGGNPLAAAVGLQVVKLLQTGEYQERATTLGHYLGSLLDGLLGHGLTEVRVAGLWAGVDVDPSCGTGRDVAESLLARGVLVKDTHGQTLRIAPPLTIEAADLAWAVDELRLALKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF04</accession>
    <name>A0A1Q2CF04_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4190 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_07690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44702">
        <property type="protein sequence ID" value="AQP44702"/>
        <property type="gene ID" value="RPIT_07690"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07690"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025241">
        <property type="entry name" value="DUF4190"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13828">
        <property type="entry name" value="DUF4190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4190" evidence="2">
        <location>
            <begin position="5"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="83" mass="8502" checksum="7C5F9C5DA940D7C1" modified="2017-04-12" version="1">MVNKLAVASLLLSLLALGGMFGFGFISVAVFGVGAGHVALQQIKCRGDRGRGLALVSLAICYLMGTWALLSVPSLLFAFASGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF18</accession>
    <name>A0A1Q2CF18_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44698">
        <property type="protein sequence ID" value="AQP44698"/>
        <property type="gene ID" value="RPIT_07660"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07660"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="261" mass="29398" checksum="C7FD47638AB90D26" modified="2017-04-12" version="1">MSLTDADREALRQIFETESNLDRWRIRARSVEEPEVGSDLALNDKIFPHMAISQLVRISLVLSGEHLRLALDSLRAKQLYPSAHFTVLRGALVGASQGVWILSPEDGQERRERGLAVLDEMYTQMEKYYNALGGLSGEEQASLDDQKSWLSDRRTGVADVRTRNAQLNLTEVVREAAEDVFTGVRQQEAVRRLWREMSADAHVLGWSLFQRSTFGPPDRRTGIGEGRASGSPSHVANAFLASYRTLKHGWSLFDRRCEAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF24</accession>
    <name>A0A1Q2CF24_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44703">
        <property type="protein sequence ID" value="AQP44703"/>
        <property type="gene ID" value="RPIT_07695"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07695"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="119" mass="12280" checksum="58EFF5FB3E308626" modified="2017-04-12" version="1">MERGAVAVGLAGLAAFQAALAIGTPWGRASYGGAHIGVLPSRLRVVSAGAALLYSGLSVAIVSRRTPLRVRRHVLTGITALMGVGAVLNGISPSWPERATWTPTTALLAALAWRARRDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF67</accession>
    <name>A0A1Q2CF67_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07895</name>
        <name evidence="3" type="ORF">SAMN05428934_11319</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07895"/>
    <dbReference type="EnsemblBacteria" id="AQP44737">
        <property type="protein sequence ID" value="AQP44737"/>
        <property type="gene ID" value="RPIT_07895"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16373">
        <property type="protein sequence ID" value="SDZ16373"/>
        <property type="gene ID" value="SAMN05428934_11319"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07895"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544454" evidence="1">
        <location>
            <begin position="20"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ16373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="425" mass="44123" checksum="49A61168633162D0" modified="2017-04-12" version="1">MAGVVLGLLCSGGVTAAHAEETAPGPLVVEVSGATTTPVVGISADKHGITDAALDVVRDDEPANVVALVDAASAVGALPMQETDEGLSVSTTAGTTTVLNRDGVAEATHAELPAVGIEVRGDTSEASAVDDAMVWEEVAPSTDVVARATETGMQLVAVLADETAPSTIEFDLVLPEGGHLVETEDGSIDIVAPVEIERIDEASLADLERRASLILGDSFDETTGELTAAQEAALSALPDLKTYTVEEERAVATIAPAWAVDANGEPVGTRYELDGATLTQVVDVTATTAFPVTADPTFWWYFRKAAACIASVAGTVVVAAKIAQITVKLFKLLRAAKPGTALNRAYQAWMKLGSNNDQRLGNLGLNLRLIAGIYQQYGSTRATQIIIARGGRIKAARDFIVYGASTIASVTSLDSCVSLVTGRNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF81</accession>
    <name>A0A1Q2CF81_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Acetylglutamate kinase</fullName>
            <ecNumber evidence="7">2.7.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">N-acetyl-L-glutamate 5-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">NAG kinase</fullName>
            <shortName evidence="7">NAGK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">argB</name>
        <name evidence="9" type="ORF">RPIT_08210</name>
        <name evidence="10" type="ORF">SAMN05428934_11533</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14629"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the acetylglutamate kinase family. ArgB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.8" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08210"/>
    <dbReference type="EnsemblBacteria" id="AQP44782">
        <property type="protein sequence ID" value="AQP44782"/>
        <property type="gene ID" value="RPIT_08210"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19684">
        <property type="protein sequence ID" value="SDZ19684"/>
        <property type="gene ID" value="SAMN05428934_11533"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08210"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00107"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003991">
        <property type="term" value="F:acetylglutamate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04250">
        <property type="entry name" value="AAK_NAGK-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00082">
        <property type="entry name" value="ArgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004662">
        <property type="entry name" value="AcgluKinase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037528">
        <property type="entry name" value="ArgB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041727">
        <property type="entry name" value="NAGK-C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000728">
        <property type="entry name" value="NAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00761">
        <property type="entry name" value="argB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 7" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="8">
        <location>
            <begin position="34"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="73"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ19684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="300" mass="31982" checksum="C92A23D4EF3084DC" modified="2017-04-12" version="1">MTSRKRSPQQPELIAKANTLIEALPWLAEYAGETVVIKYGGNAMTDDALKRAFAEDIVFLRRVGLKPVVVHGGGPQISSMLRKLDIDSEFRGGLRVTTPEAMDVVRMVLVGQVGRELVNLINQHGPFAVGMSGEDGGLFTAKRRGLMVDDEEIDLGLVGDVKAVDPSSLNDLIDAGRIPVVATVAPDRDGQVHNVNGDTAAAALAVALGAKRLVMLTNVAGVYENYPDEDSILTQVTADDVRAMLPTLDAGMIPKMEACLRAVEGGVTSATVIDGRVPHCLLLEIFTDEGIGTMVIKGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFA3</accession>
    <name>A0A1Q2CFA3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Phenylalanine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="14">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Phenylalanyl-tRNA synthetase beta subunit</fullName>
            <shortName evidence="14">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">pheT</name>
        <name evidence="19" type="ORF">RPIT_08255</name>
        <name evidence="20" type="ORF">SAMN05428934_11524</name>
    </gene>
    <organism evidence="19 21">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 21" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 21">RP1T</strain>
        </source>
    </reference>
    <reference evidence="20 22" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 22">RP1</strain>
        </source>
    </reference>
    <reference evidence="19" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 14">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="14"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08255"/>
    <dbReference type="EnsemblBacteria" id="AQP44791">
        <property type="protein sequence ID" value="AQP44791"/>
        <property type="gene ID" value="RPIT_08255"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19489">
        <property type="protein sequence ID" value="SDZ19489"/>
        <property type="gene ID" value="SAMN05428934_11524"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08255"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00769">
        <property type="entry name" value="PheRS_beta_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02796">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00283">
        <property type="entry name" value="Phe_tRNA_synth_beta1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005121">
        <property type="entry name" value="Fdx_antiC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036690">
        <property type="entry name" value="Fdx_antiC-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045060">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004532">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041616">
        <property type="entry name" value="PheRS_beta_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033714">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005147">
        <property type="entry name" value="tRNA_synthase_B5-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947">
        <property type="entry name" value="PTHR10947"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03484">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03147">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17759">
        <property type="entry name" value="tRNA_synthFbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00874">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00896">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54991">
        <property type="entry name" value="SSF54991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00472">
        <property type="entry name" value="pheT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51483">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51447">
        <property type="entry name" value="FDX_ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 14 20" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 14 19" id="KW-0436">Ligase</keyword>
    <keyword evidence="10 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 14" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 15" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="16">
        <location>
            <begin position="42"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="B5" evidence="18">
        <location>
            <begin position="412"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="FDX-ACB" evidence="17">
        <location>
            <begin position="736"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="471"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="474"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="475"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="AQP44791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="SDZ19489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="829" mass="87897" checksum="019C31EC1E05425C" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFB0</accession>
    <name>A0A1Q2CFB0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UPF0060 membrane protein RPIT_07885</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_07885</name>
        <name evidence="7" type="ORF">SAMN05428934_11317</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the UPF0060 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44735">
        <property type="protein sequence ID" value="AQP44735"/>
        <property type="gene ID" value="RPIT_07885"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16340">
        <property type="protein sequence ID" value="SDZ16340"/>
        <property type="gene ID" value="SAMN05428934_11317"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07885"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00010">
        <property type="entry name" value="UPF0060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003844">
        <property type="entry name" value="UPF0060"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36116">
        <property type="entry name" value="PTHR36116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02694">
        <property type="entry name" value="UPF0060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ16340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="111" mass="11797" checksum="AD3E9CE22CF6AA12" modified="2017-04-12" version="1">MTVVKSIILFVAAALTEIGGAWLIWQGVREHRGLLWVAGGVVALGLYGFVATLQPDANFGRILAAYGGVFVAGSLLWGMVMDGFRPDRYDVVGALICLVGVAVIMYSPRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFB8</accession>
    <name>A0A1Q2CFB8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_08030</name>
        <name evidence="6" type="ORF">SAMN05428934_11347</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08030"/>
    <dbReference type="EnsemblBacteria" id="AQP44760">
        <property type="protein sequence ID" value="AQP44760"/>
        <property type="gene ID" value="RPIT_08030"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16911">
        <property type="protein sequence ID" value="SDZ16911"/>
        <property type="gene ID" value="SAMN05428934_11347"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08030"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="9"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDZ16911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="246" mass="27553" checksum="83601E3EA880EF1E" modified="2017-04-12" version="1">MTEEPTEGVRLQKVLAAAGIASRRASEMLIDEGRVEVNGKVVTEQGRRVNPETDHIRVDGARIPPPRRHQYLVLNKPRGVVSTMDDPEGRPTLTDYLPRTKERLFHVGRLDTDTEGLIVLTNDGEFANRLSHPRYEVPKTYHVQAAGAMDNKTIRRLEKGVTLEDGKVQPDNVKLVSRAQDRTLLAVTLHEGRNRVVRRMFDAVGHPVDRLSRTMIGPIRLGNLPVGETRELTRDELGALLDLVGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFG3</accession>
    <name>A0A1Q2CFG3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_08660</name>
        <name evidence="8" type="ORF">SAMN05428934_10742</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08660"/>
    <dbReference type="EnsemblBacteria" id="AQP44851">
        <property type="protein sequence ID" value="AQP44851"/>
        <property type="gene ID" value="RPIT_08660"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97092">
        <property type="protein sequence ID" value="SDY97092"/>
        <property type="gene ID" value="SAMN05428934_10742"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08660"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="1"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="2"/>
            <end position="9"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY97092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="207" mass="22773" checksum="FA1BEA2320A44A2A" modified="2017-04-12" version="1">MGKSGSGKSTLGRVLCGLIEPTEGEIRYEGLAKVDYSREHFYSHVGYVPQEVHLLNRTILENITMSSTELGEDDARRAATEAMVGADIQALPMGYQTLVAEMGGNFSGGQRQRIALARALVRQPKVLVLDEATSSLDTHNESRIASMLREKSCTVIVIAHRMSTVVDADRIYVMEDGEIMESGSHDELLMSGPRYRDLFASSLAVRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFN8</accession>
    <name>A0A1Q2CFN8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09130</name>
        <name evidence="3" type="ORF">SAMN05428934_107139</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY99012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09130"/>
    <dbReference type="EnsemblBacteria" id="AQP44931">
        <property type="protein sequence ID" value="AQP44931"/>
        <property type="gene ID" value="RPIT_09130"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY99012">
        <property type="protein sequence ID" value="SDY99012"/>
        <property type="gene ID" value="SAMN05428934_107139"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09130"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="276"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY99012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="772" mass="85477" checksum="BFD1442995FB530C" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFN9</accession>
    <name>A0A1Q2CFN9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS1634 family transposase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transposase DDE domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09080</name>
        <name evidence="3" type="ORF">SAMN05428934_107129</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09080"/>
    <dbReference type="EnsemblBacteria" id="AQP44923">
        <property type="protein sequence ID" value="AQP44923"/>
        <property type="gene ID" value="RPIT_09080"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98815">
        <property type="protein sequence ID" value="SDY98815"/>
        <property type="gene ID" value="SAMN05428934_107129"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09080"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="169"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY98815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="497" mass="55221" checksum="1ADD1C79267B621D" modified="2017-04-12" version="1">MSPYVRTVKTASGATAVQVVWSNKRGAKEMDHIGSAHTAEDVEVLKAAARQRMSAGQDELDFGDGRPRGQALPIRSSRAEFLWEALSAAFRAVGLEKTSGADEVFKQLVLARVIEPTSKLEAIRVLDEVGIQAASYPTMNRRLPMYATDTWRRGLAAGFADLVGLGPATLILYDVTTLYFETDEGDGFREPGFSKERRLEPQITVGLLTDSHGMPLMVHAFEGNKAETQTMIPVLAEFMAAHRIAEVTVVADAGMLSDGNLRALAGAGLRFIVGQPIPQIPAKLEAWMKAHPGKDPEDAMVLRQKWSRGPAGAQQPEVIYYQYRADRARRSLRGIDEQVRKAQAAIDGRAPVKRNRFIKLTGAAKELNLELEHKTRTLAGWKAYITNLESPSPEFVIGAYHQLWQVEKSFRMSKSDLRARPIYHHKRESIEAHLTIVFASLAVSRWLEARTGWSIKKLVKNLRRYRTIEIQAGDTLVTAADPLPADLTEILDRIHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFR4</accession>
    <name>A0A1Q2CFR4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">[lysine-biosynthesis-protein LysW]---L-2-aminoadipate ligase/ribosomal protein S6--L-glutamate ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09290</name>
        <name evidence="4" type="ORF">SAMN05428934_102451</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY61122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09290"/>
    <dbReference type="EnsemblBacteria" id="AQP44956">
        <property type="protein sequence ID" value="AQP44956"/>
        <property type="gene ID" value="RPIT_09290"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY61122">
        <property type="protein sequence ID" value="SDY61122"/>
        <property type="gene ID" value="SAMN05428934_102451"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09290"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="111"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY61122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="328" mass="36203" checksum="AABC33A1AE5E3C25" modified="2017-04-12" version="1">MSGPTDRRPLVMVLGDDIDDLDHSVLFPALRARGVEVTRVHPRDLVTYMDGPDTTFAVGGQTIRPDLVVGWVLDDLLLQGMAQLDVLARAGIVIINDAITLFRAQNNYINSSLLSDGGVLRYPVISGEDPQALRDWASEHGYPVVVKPVRGFGGRGLRRLLNDRELEDLLGDLRQDDEQYYVVPWVENPGRDIRVYTVAHHPVFAMYRYAPPGSWVTNILAGGEKAMCPLNDRLADLAERASRAAGTLLGGVDLAENLETGDLVVYEVNSCPSSEPAALEAVADFLVSVVEQGLDAAVASWRPARVHDHFNPDRSLFHRTPRERLHRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFZ1</accession>
    <name>A0A1Q2CFZ1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">N5-carboxyaminoimidazole ribonucleotide synthase</fullName>
            <shortName evidence="3 5">N5-CAIR synthase</shortName>
            <ecNumber evidence="3 5">6.3.4.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3 5">5-(carboxyamino)imidazole ribonucleotide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">purK</name>
        <name evidence="7" type="ORF">RPIT_09640</name>
        <name evidence="8" type="ORF">SAMN05428934_102377</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="function">
        <text evidence="5">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 5">
            <text>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ATP + hydrogencarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19317"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the PurK/PurT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.18" evidence="3 5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY59138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09640"/>
    <dbReference type="EnsemblBacteria" id="AQP45017">
        <property type="protein sequence ID" value="AQP45017"/>
        <property type="gene ID" value="RPIT_09640"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59138">
        <property type="protein sequence ID" value="SDY59138"/>
        <property type="gene ID" value="SAMN05428934_102377"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09640"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00942"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034028">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004638">
        <property type="term" value="F:phosphoribosylaminoimidazole carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01928">
        <property type="entry name" value="PurK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003135">
        <property type="entry name" value="ATP-grasp_carboxylate-amine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005875">
        <property type="entry name" value="PurK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040686">
        <property type="entry name" value="PurK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02222">
        <property type="entry name" value="ATP-grasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17769">
        <property type="entry name" value="PurK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01161">
        <property type="entry name" value="purK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 3 5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="6">
        <location>
            <begin position="107"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="184"/>
            <end position="187"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="270"/>
            <end position="271"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY59138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="386" mass="41480" checksum="4861AD00540FD215" modified="2017-04-12" version="1">MTRRYTVSIAGGGQLARMMHQAAIALGIDVRLLAEAPGVSAAQVIPDSIVGDYHDLDTLKLLVEGADALTFDHEHVPTRHLRELEQVVAVRPGPDALVFAQDKALMRQRMQELGVACPTFAVCETLDELVAFGEAQGWPIIAKTSRGGYDGKGVWKLDGPDDARVPFAGLAETSAGERVRIVAEEYIDFTRELSALVVRSASGQVVAYPVSESVQEDGICVETVTPASGLDGDAAAGLQEMAIRIAAELGVVGVLAVELMEAWDGRIVVNELAMRPHNTGHWTIDGARTSQFENHIRAVLDLPLGSPELRDGVAVMRNVLGGVEPDLTGALTHVFARDREVRVHLYGKEVRAGRKVGHVTCLGTDLDDVRRRAHHAAGYLMGDPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFZ2</accession>
    <name>A0A1Q2CFZ2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Nucleoside ABC transporter membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_09775</name>
        <name evidence="9" type="ORF">SAMN05428934_102350</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY58380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09775"/>
    <dbReference type="EnsemblBacteria" id="AQP45038">
        <property type="protein sequence ID" value="AQP45038"/>
        <property type="gene ID" value="RPIT_09775"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY58380">
        <property type="protein sequence ID" value="SDY58380"/>
        <property type="gene ID" value="SAMN05428934_102350"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09775"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY58380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="418" mass="43870" checksum="AACCFA92E60A9DFC" modified="2017-04-12" version="1">MSEQPHKSTEQPPAPESTVTEPVVAAPRTRQPRPSWVNTLIITIASLLLAFIVAAVVMVFSDAEVAATWAYFFAQPGDALAASWDKIASTFYAMYVGSMGSWVAITNTTAEAAPLICAGLGVAVAFRAGLFNIGAQGQAMLGALSAAFLGFSVKGLPLFLHLPLVILVGILAGAIWGGIVGLIKARTGAHEVILTIMMNYIAGSLLAFLMLQPLFQAPGRVDPISPVLEWTATMPRIDGTRLHLGFILALLAALLVWWLLERTKFGIHLKAVGLNPNAAATAGASVPVITMLSMSLAGALAGLGGVQMVTAPELLTGFPPQMTGTIIGTLGFDAITVALLGRSRPLGVVFAGLLFGALKASRRTMVTMAGTPDRLTDLIQALIVLFVAAPAFVVWVLPFLKERKAKRVVAESRKVAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG40</accession>
    <name>A0A1Q2CG40_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Chaperonin GroEL</fullName>
            <ecNumber evidence="9">5.6.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">60 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Chaperonin-60</fullName>
            <shortName evidence="9">Cpn60</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">groEL</name>
        <name evidence="9" type="synonym">groL</name>
        <name evidence="12" type="ORF">RPIT_09965</name>
        <name evidence="13" type="ORF">SAMN05428934_102313</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 11">Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9 11">Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell surface</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Secreted</location>
            <location evidence="8">Capsule</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9 10">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.7" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY57256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09965"/>
    <dbReference type="EnsemblBacteria" id="AQP45074">
        <property type="protein sequence ID" value="AQP45074"/>
        <property type="gene ID" value="RPIT_09965"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57256">
        <property type="protein sequence ID" value="SDY57256"/>
        <property type="gene ID" value="SAMN05428934_102313"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09965"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042603">
        <property type="term" value="C:capsule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018370">
        <property type="entry name" value="Chaperonin_Cpn60_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="SSF52029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="SSF54849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00296">
        <property type="entry name" value="CHAPERONINS_CPN60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="29"/>
            <end position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="86"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="493"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP45074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY57256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="526" mass="55717" checksum="D822854498D4B4F3" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG48</accession>
    <name>A0A1Q2CG48_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha-mannosyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Phosphatidylinositol alpha 1,6-mannosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_10060</name>
        <name evidence="6" type="ORF">SAMN05428934_102293</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10060"/>
    <dbReference type="EnsemblBacteria" id="AQP45091">
        <property type="protein sequence ID" value="AQP45091"/>
        <property type="gene ID" value="RPIT_10060"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56767">
        <property type="protein sequence ID" value="SDY56767"/>
        <property type="gene ID" value="SAMN05428934_102293"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10060"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
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        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="4">
        <location>
            <begin position="14"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="3">
        <location>
            <begin position="193"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY56767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="378" mass="40771" checksum="29A6D9A259B7CB0A" modified="2017-04-12" version="1">MRVAIIAESFLPQINGVTNSVLRILEHLAARGHEALVIAPSDGGRTPESYAGFPVEAVPSIGLPGYGAVRVATTTGFHVSRLLAQFAPDVVHLAAPFSLGYKAASVATRLNLPIVAIYQTEVPTYATRYGFPQLEPVLWHQVRQVHSLASLNFAPSTFARDQLVAQGIPRVGVWGRGVDSVRFHPAKRSQDLRRQLAPNGERLIGFMGRLATEKRVEDLAAVADVPGTRLVIIGDGPLRGHLEASMPSAAFLGQLTGEDLAVALASLDLFVHPGELETFCQAIQEAKASGLPVIAPRRGGPIDLIDQSRTGWLYEPGNLDELRSHTADLIGDDAKRRAFGDAARDSILDRTWARLCDELVGHYEKAIRMAVRGPEVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG57</accession>
    <name>A0A1Q2CG57_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2-dehydro-3-deoxygluconokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_10095</name>
        <name evidence="5" type="ORF">SAMN05428934_102286</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10095"/>
    <dbReference type="EnsemblBacteria" id="AQP45096">
        <property type="protein sequence ID" value="AQP45096"/>
        <property type="gene ID" value="RPIT_10095"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56583">
        <property type="protein sequence ID" value="SDY56583"/>
        <property type="gene ID" value="SAMN05428934_102286"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10095"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="17"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY56583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="286" mass="30042" checksum="D0CE83C58397A649" modified="2017-04-12" version="1">MTLDVVVVGNAGVDTNVYLAGADVDWSRESNFTENRDYVGQAGGYAARGYAQLGYRTGFIGSLGDDPAGGMVRAAFARDGIDQRGVFNDPSGTARSVNIMGSDGSRKNFYDGRGHLDLDPPRATEILAGVQLVHMNLANWARHLIPGAHAAGATVACDLQDVADLDDPYRRAFVDGAHYLFASAANSKGEELARALMRRRPDATVVIGLGARGCAVADADGYEEFPAPPSDLPLVDTNGAGDSLAVGFLSARVLDGLPVVAAVARGQAAARWCCAQRASTDHLYRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG86</accession>
    <name>A0A1Q2CG86_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protease-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_10270</name>
        <name evidence="4" type="ORF">SAMN05428934_102251</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10270"/>
    <dbReference type="EnsemblBacteria" id="AQP45129">
        <property type="protein sequence ID" value="AQP45129"/>
        <property type="gene ID" value="RPIT_10270"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55612">
        <property type="protein sequence ID" value="SDY55612"/>
        <property type="gene ID" value="SAMN05428934_102251"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10270"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07023">
        <property type="entry name" value="S49_Sppa_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004634">
        <property type="entry name" value="Pept_S49_pIV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002142">
        <property type="entry name" value="Peptidase_S49"/>
    </dbReference>
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        <property type="entry name" value="Peptidase_S49"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001217">
        <property type="entry name" value="Protease_4_SppA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S49" evidence="2">
        <location>
            <begin position="110"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S49" evidence="2">
        <location>
            <begin position="342"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR001217-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY55612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="558" mass="59523" checksum="7DCE005A7E848A48" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGA3</accession>
    <name>A0A1Q2CGA3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Biotin synthase</fullName>
            <ecNumber evidence="3 13">2.8.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">bioB</name>
        <name evidence="17" type="ORF">RPIT_09975</name>
        <name evidence="18" type="ORF">SAMN05428934_102311</name>
    </gene>
    <organism evidence="17 19">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 19" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">RP1T</strain>
        </source>
    </reference>
    <reference evidence="18 20" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">RP1</strain>
        </source>
    </reference>
    <reference evidence="17" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>(4R,5S)-dethiobiotin + [sulfur carrier]-SH + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + [sulfur carrier]-H + biotin + 2 L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:22060"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:149473"/>
            <dbReference type="EC" id="2.8.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="13 14">Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="13 14">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 13">Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the radical SAM superfamily. Biotin synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.6" evidence="3 13"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY57205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09975"/>
    <dbReference type="EnsemblBacteria" id="AQP45075">
        <property type="protein sequence ID" value="AQP45075"/>
        <property type="gene ID" value="RPIT_09975"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57205">
        <property type="protein sequence ID" value="SDY57205"/>
        <property type="gene ID" value="SAMN05428934_102311"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09975"/>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00162"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004076">
        <property type="term" value="F:biotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01694">
        <property type="entry name" value="BioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010722">
        <property type="entry name" value="BATS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002684">
        <property type="entry name" value="Biotin_synth/BioAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024177">
        <property type="entry name" value="Biotin_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22976">
        <property type="entry name" value="PTHR22976"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06968">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001619">
        <property type="entry name" value="Biotin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00876">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00433">
        <property type="entry name" value="bioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13 14" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 13 14" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9 13" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="11 13 14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="16">
        <location>
            <begin position="49"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="322"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001619-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="AQP45075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="SDY57205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="351" mass="37895" checksum="69EAEA3D3D2AE1C3" modified="2017-04-12" version="1">MDLNALASRVIDGGTITTDEALAVLRLPDELTYELVAAAGRVRRHFHGATMKVNYLVNLKSGKCPEDCFYCSQRLGSDAEILRYTWLTHEDALEAAKAGIRAGAGRVCLVASGRGPSNRDVDRVGRIIEDLKEDNPGVEVCACLGILKDGQAERLASAGADAYNHNLNTAESHYDNICTTHDYDDRKDTVQHAREHGLSACSGLIAGMGESDEQLVEVAFQLKEIGADSVPVNFLMPFDGTPLEGHSELTPQKCLRILAMIRLVHGSADVRVSAGREQHLRSLQPLSLEICNSLFLGDYLTSQGQAGEEDLEMLADGGYTVWGADGQRSPGAPPRPEIRRRGAGTRVAANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGE4</accession>
    <name>A0A1Q2CGE4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transglutaminase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transglutaminase-like enzyme, putative cysteine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10195</name>
        <name evidence="3" type="ORF">SAMN05428934_102266</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10195"/>
    <dbReference type="EnsemblBacteria" id="AQP45115">
        <property type="protein sequence ID" value="AQP45115"/>
        <property type="gene ID" value="RPIT_10195"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56007">
        <property type="protein sequence ID" value="SDY56007"/>
        <property type="gene ID" value="SAMN05428934_102266"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10195"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013589">
        <property type="entry name" value="Bac_transglu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08379">
        <property type="entry name" value="Bact_transglu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TGc" evidence="1">
        <location>
            <begin position="168"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY56007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="280" mass="30994" checksum="4F4A85CACEA6628A" modified="2017-04-12" version="1">MSQYRIVHTTGYRYGGGATDSFNEARMTPLTSRRQLVLSSRLDISPVAWTHAYRDYWGTSAVAFEVHERHSELSVVATSTVDIHEVERATEPIGWEGLSDPDLRDRYVEFLTQTSYVRPHRDVARVAESVRRSAATPGDAVVELTRRLRDRVGYVPGVTQVHTLAGEVWDAGAGVCQDLAHLTLGGLRSIGVPARYVSGYVVQRTDPELGEAMVGESHAWIQYFDGEWLGFDPTSQAEPRGSHVEVGFGRDYSDVPPLKGIYTGSGGSEMYVSVEMTRLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGE6</accession>
    <name>A0A1Q2CGE6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Predicted oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10610</name>
        <name evidence="3" type="ORF">SAMN05428934_102183</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY53588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10610"/>
    <dbReference type="EnsemblBacteria" id="AQP45192">
        <property type="protein sequence ID" value="AQP45192"/>
        <property type="gene ID" value="RPIT_10610"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY53588">
        <property type="protein sequence ID" value="SDY53588"/>
        <property type="gene ID" value="SAMN05428934_102183"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10610"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="16"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY53588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="328" mass="35644" checksum="D10FC5BFA6C078AF" modified="2017-04-12" version="1">MEKRILGKTDRAVGVVGQGCWQFGGDWGDVGDGAAMGVLHAAADAGVTFFDTADVYGDGHSEELVGRFIKERGDSGLMVATKLGRRADPFVAETYTRENLRAWTERSLKLLGVDTIDLTQLHCPPTPVYSTDSVYDALDEMVDEGKLRNYGVSVETVDEAMTALERPGVATIQIILNVFRRKPLERVLPAAREAGVGIIARVPLASGLLTGKFSEDSSFAATDHRSYNRFGEAFDQGETFSGVPYELGVQAAREFAEVVPEGITPAQFALRWIIDQPGVSVVIPGASRAEQAEANAAAGSLPELTPAQLAALERIYDRRIREFVHDRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGH4</accession>
    <name>A0A1Q2CGH4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lincomycin resistance protein LmrB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Lincosamide nucleotidyltransferase A/C/D/E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10435</name>
        <name evidence="2" type="ORF">SAMN05428934_102218</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY54710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_044496367.1">
        <property type="nucleotide sequence ID" value="NZ_FNPU01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45160">
        <property type="protein sequence ID" value="AQP45160"/>
        <property type="gene ID" value="RPIT_10435"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY54710">
        <property type="protein sequence ID" value="SDY54710"/>
        <property type="gene ID" value="SAMN05428934_102218"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10435"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY54710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="164" mass="18116" checksum="1EE07DBB62D6AC1E" modified="2017-04-12" version="1">MTFSGMDAAEVVRVVGWLEERSVVYQVNGGWAVDALHGSQTRSHGDLDVFVDSTTVDALMEWLLGRGYSIVEDWRPIRVELRAGDRAVDIHPMDVDCVGDGVQQGFGEDSFVHRARERAVGVIGDRSVVVACAARLMALRLGYDLRPEDRHDLDVLGRLVADHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGJ7</accession>
    <name>A0A1Q2CGJ7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sirohydrochlorin ferrochelatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_10880</name>
        <name evidence="4" type="ORF">SAMN05428934_102129</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY51912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10880"/>
    <dbReference type="EnsemblBacteria" id="AQP45236">
        <property type="protein sequence ID" value="AQP45236"/>
        <property type="gene ID" value="RPIT_10880"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY51912">
        <property type="protein sequence ID" value="SDY51912"/>
        <property type="gene ID" value="SAMN05428934_102129"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10880"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002762">
        <property type="entry name" value="CbiX-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01903">
        <property type="entry name" value="CbiX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY51912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="229" mass="23721" checksum="C9FFF8FB21AB5CDB" modified="2017-04-12" version="1">MKPALVVCAHGTDDPDGRATVVAIAEAAAGRLPDVTVEVAYVDVQEPKLDAVVDRLVAAGEHVVVVPILLTLGFHTEVDVQEAIADHPGRAVSTGPLGPDPRLADALVDRLREARVPEDTAVVVGVAGSSRPEAAEVGRGVARSVQSRWSGPVTVGFLAVAEPSVPDAVAAARSTGPVALASYLIGRGFFQRKLAKAGGDFLAEPLGDHPGLVDVVVDRYRSGCRHLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGL2</accession>
    <name>A0A1Q2CGL2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11020</name>
        <name evidence="3" type="ORF">SAMN05428934_10299</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY50994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11020"/>
    <dbReference type="EnsemblBacteria" id="AQP45259">
        <property type="protein sequence ID" value="AQP45259"/>
        <property type="gene ID" value="RPIT_11020"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY50994">
        <property type="protein sequence ID" value="SDY50994"/>
        <property type="gene ID" value="SAMN05428934_10299"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11020"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY50994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="252" mass="27014" checksum="B151E46A81D5007C" modified="2017-04-12" version="1">MLAGILIAIVVVAGIAVALPWVAAQKPADVELESDPAERFADSMRIIRSDITDYVAEQDAAEVSTPLTRRAELNELRLIAKQAAKRRRTTVLLLLTALVVVTVLSALSITPWWSLAIPGTPLIAFLAVARFTVVAMHRSLDARAAAVRAGYDDAEDTTTIDLSAHAETEEFEISVDLTMPTTMGALWDPIPITPATYVSQPLLPRTVRTIDLSAPVASAPLVPTADHPDAVLDDEETLGAPITELRPRAVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGN1</accession>
    <name>A0A1Q2CGN1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Large conductance mechanosensitive channel</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Mechanosensitive ion channel protein MscL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_11045</name>
        <name evidence="7" type="ORF">SAMN05428934_10294</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY50835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11045"/>
    <dbReference type="EnsemblBacteria" id="AQP45264">
        <property type="protein sequence ID" value="AQP45264"/>
        <property type="gene ID" value="RPIT_11045"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY50835">
        <property type="protein sequence ID" value="SDY50835"/>
        <property type="gene ID" value="SAMN05428934_10294"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11045"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037673">
        <property type="entry name" value="MSC/AndL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036019">
        <property type="entry name" value="MscL_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30266">
        <property type="entry name" value="PTHR30266"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01741">
        <property type="entry name" value="MscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81330">
        <property type="entry name" value="SSF81330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY50835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="122" mass="13309" checksum="A3F202ABEF24118A" modified="2017-04-12" version="1">MKGFKEFLMRGNLIELAVAFVMAAAFAKVVETFTAMFMDLLGKLGGTPDFSSYNPGGISVGAFLTALVAFFIVAAIIYFGVVLPYTKAKERFDKSVEEAPALTKSEQLLEEIRDSLRGRNAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGN5</accession>
    <name>A0A1Q2CGN5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Enolase</fullName>
            <ecNumber evidence="8">4.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">2-phospho-D-glycerate hydro-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">2-phosphoglycerate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">eno</name>
        <name evidence="13" type="ORF">RPIT_10705</name>
        <name evidence="14" type="ORF">SAMN05428934_102164</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="8">The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell surface</location>
        </subcellularLocation>
        <text evidence="8">Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the enolase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY53022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10705"/>
    <dbReference type="EnsemblBacteria" id="AQP45205">
        <property type="protein sequence ID" value="AQP45205"/>
        <property type="gene ID" value="RPIT_10705"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY53022">
        <property type="protein sequence ID" value="SDY53022"/>
        <property type="gene ID" value="SAMN05428934_102164"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10705"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="PTHR11902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Enolase_N" evidence="12">
        <location>
            <begin position="4"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase_C" evidence="11">
        <location>
            <begin position="139"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="362"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8 9">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="335"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent; in inhibited form" evidence="8">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="386"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP45205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY53022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="426" mass="45144" checksum="DE62192B55C7F3FA" modified="2017-04-12" version="1">MASIEFIQAREILDSRGNPTIEVEVELESGATGRAAVPSGASTGAFEAAELRDGDKGRFGGKGVLTAVQNATEVIGEEILGLDASEQRIVDLAMIELDGTDNKSKLGANAILGVSLAVAHAAAEEAGLPLYKYVGGPNAHILPVPMMNILNGGSHADSNVDIQEFMIAPIGAESFAQAVEMGAGVYHALKAVLKEKGLNTGLGDEGGFAPNLDSNRAALDLIMEAIRKAGYEPGSDVALALDVAASEFFNDGGYEFEGATKTAEEMVDYYAELVDAYPMVSIEDPLNEEDWDGWKLMTDRLGDMVQIVGDDLFVTNVTRLQKGIDTKTANALLVKVNQIGSLSETIDAVDLAHRNGFKTMMSHRSGETEDVTIADLAVALGCGQIKSGAPARTDRVAKYNQLLRIEDDLDEAAVYAGRSAFPRFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGQ6</accession>
    <name>A0A1Q2CGQ6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">MFS transporter, NNP family, nitrate/nitrite transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_10905</name>
        <name evidence="8" type="ORF">SAMN05428934_102123</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY51745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10905"/>
    <dbReference type="EnsemblBacteria" id="AQP45240">
        <property type="protein sequence ID" value="AQP45240"/>
        <property type="gene ID" value="RPIT_10905"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY51745">
        <property type="protein sequence ID" value="SDY51745"/>
        <property type="gene ID" value="SAMN05428934_102123"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10905"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17341">
        <property type="entry name" value="MFS_NRT2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="PTHR23515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="385"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY51745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="452" mass="47654" checksum="E6B0776AEB93AF48" modified="2017-04-12" version="1">MTTTRIHPPTQRATAVELTHRPGRWIDGWDPENPVQWGSVGRPIARRNLVLSIFAEFLGFAVWALWSIVVPQLNGVGFDLSVNQMFWLVSTPALVGATLRLPYTFAVPRFGGRNWTVVSALLLLLPAGTLAWAVNHPELPFGVLMGIAALAGVGGGNFASSMANISFFFPAKEKGAALGLNAAGGNVGTAAVQLAVPIVITLGAGLSLDRAGLMFIPLALLAAVLAWRGMDNLSNAKSDPRAYAVALRHPHTWILSFIYIGTFGSFIGYSATFPTLLNNLFPTVTLSLAFLGALVGSVSRPLGGHLSDRLGGALVTCVSFVAMAVGAVGAIIGLQEQSFPIFFLSFLWLFVFTGIGNGSVYRMIPAVFSGTSASDPMSLVAAGRAAAGCIGIAGAVGAFGGFLIPQGFALSRTLTGNLQSALWVMVAVYLVMLGVTWFTYLRRGSRLAELRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGR7</accession>
    <name>A0A1Q2CGR7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7 8">2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase</fullName>
            <shortName evidence="7">MECDP-synthase</shortName>
            <shortName evidence="7">MECPP-synthase</shortName>
            <shortName evidence="7">MECPS</shortName>
            <ecNumber evidence="3 7 8">4.6.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ispF</name>
        <name evidence="10" type="ORF">RPIT_11290</name>
        <name evidence="11" type="ORF">SAMN05428934_10245</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7 8">
            <text>4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP</text>
            <dbReference type="Rhea" id="RHEA:23864"/>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
            <dbReference type="ChEBI" id="CHEBI:58483"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="4.6.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="7">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 4/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the IspF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.12" evidence="3 7 8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY49418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11290"/>
    <dbReference type="EnsemblBacteria" id="AQP45306">
        <property type="protein sequence ID" value="AQP45306"/>
        <property type="gene ID" value="RPIT_11290"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY49418">
        <property type="protein sequence ID" value="SDY49418"/>
        <property type="gene ID" value="SAMN05428934_10245"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11290"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008685">
        <property type="term" value="F:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00554">
        <property type="entry name" value="MECDP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00107">
        <property type="entry name" value="IspF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003526">
        <property type="entry name" value="MECDP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020555">
        <property type="entry name" value="MECDP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036571">
        <property type="entry name" value="MECDP_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43181">
        <property type="entry name" value="PTHR43181"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02542">
        <property type="entry name" value="YgbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69765">
        <property type="entry name" value="SSF69765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00151">
        <property type="entry name" value="ispF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01350">
        <property type="entry name" value="ISPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="6 7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YgbB" evidence="9">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="7">
        <location>
            <begin position="8"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="7">
        <location>
            <begin position="35"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="7">
        <location>
            <begin position="57"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="7">
        <location>
            <begin position="130"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>4-CDP-2-C-methyl-D-erythritol 2-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP45306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY49418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="160" mass="16033" checksum="C266EE1B26A2B3DA" modified="2017-04-12" version="1">MRVGIGTDVHRLERGVPMWVAGLHFPEEEAGLSGHSDGDVAAHAACDALLSAAGLGDLGSNYGTSAPEWAGASGAAFLAETARRVRAAGFDIANVAVQVIGNRPKMAPRRAEAEAAMSAALDAPVTVSATTTDGLGLTGRGEGVAAMAVALLATGRSPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGZ8</accession>
    <name>A0A1Q2CGZ8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11770</name>
        <name evidence="3" type="ORF">SAMN05428934_106121</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11770"/>
    <dbReference type="EnsemblBacteria" id="AQP45392">
        <property type="protein sequence ID" value="AQP45392"/>
        <property type="gene ID" value="RPIT_11770"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93363">
        <property type="protein sequence ID" value="SDY93363"/>
        <property type="gene ID" value="SAMN05428934_106121"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11770"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY93363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="267" mass="29489" checksum="C1275304C978EA82" modified="2017-04-12" version="1">MDRLHPDPEHPGAFWVRFGPTGQSWVDPARPDFLAFEYVQHIAMLLDHTVLDAPPERRLRVVHIGGAGMSLPRWIAWRRPHTAQVVCEPDAELTEEVRRKLPLPPRSGIKVRDVDGRAGLAAMPDEWADVVIVDAFDGAQVPGELATAEALDHLRRVVRDEAVVIYNVTDRAPFDWGKRLAGGLAERWPHLMIGMEPVVAKGKRFGNVVMAASVARPDAKGVERESLKLTIGYRWLTGRDARAWPGGALPLTDATAEPSPGPLGRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH60</accession>
    <name>A0A1Q2CH60_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12125"/>
    <dbReference type="EnsemblBacteria" id="AQP45458">
        <property type="protein sequence ID" value="AQP45458"/>
        <property type="gene ID" value="RPIT_12125"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12125"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="2"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="126" mass="13589" checksum="D3CA3D622D3B41A3" modified="2017-04-12" version="1">MELKMCSLHVTDPDLAYRFYTDVLGFETMIAMPEHHVYVVAGKGQTTGLLLEPSDHPVARAYMDGLRAENLPALVVGTDDLDAAIDRLKAAGVRFVGERFSDPSGTAINFDDGVGNLIQLHEGASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH89</accession>
    <name>A0A1Q2CH89_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12315</name>
        <name evidence="3" type="ORF">SAMN05428934_10613</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY90943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45488">
        <property type="protein sequence ID" value="AQP45488"/>
        <property type="gene ID" value="RPIT_12315"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY90943">
        <property type="protein sequence ID" value="SDY90943"/>
        <property type="gene ID" value="SAMN05428934_10613"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12315"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY90943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="145" mass="15528" checksum="77E52EC2D9B0B196" modified="2017-04-12" version="1">MSKTVHVITPRPPVRALVIAAVASLVGAVLLVLALGNDWHPVAVILSALLLAAGLLLAVAAFIAPSRQAVTLTIDDEGYRVNGGGKESSGQWADVSRLTQSEDGSRLTIHHGPERRNHLVFQGSDPSQIRRVATDIRRQLQRFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH90</accession>
    <name>A0A1Q2CH90_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Multiple sugar transport system permease protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_11960</name>
        <name evidence="7" type="ORF">SAMN05428934_10683</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11960"/>
    <dbReference type="EnsemblBacteria" id="AQP45425">
        <property type="protein sequence ID" value="AQP45425"/>
        <property type="gene ID" value="RPIT_11960"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92499">
        <property type="protein sequence ID" value="SDY92499"/>
        <property type="gene ID" value="SAMN05428934_10683"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11960"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="242"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="72"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY92499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="274" mass="30255" checksum="A7ACB914D1BA0D57" modified="2017-04-12" version="1">MKGNRVLTSVRYGVLVALALLFLLPFYVIVRNAFSTQGNITAPRWNWLPDQFNLTNLDSLLANDSIGIGRAMLNSGIMAVLQTGGTVVVSVMAGYALARYTHRLAKFLLGLTLFTLMVPATTTFLPMFIMTAQLGWVDTFRGLVIPGMFSAFATYLFRQFFLDFPVELEDAALVDGCNPWTAFWRIVAPNSTGIIAAVSTIILIGSWNAFLWPTLIGRDATRTVQVALSQFMTSQGVRYPELFMGSLVAILPMLAVFLFLQRYLVQGLTTSGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHA3</accession>
    <name>A0A1Q2CHA3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional attenuator, LytR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_12310</name>
        <name evidence="6" type="ORF">SAMN05428934_10614</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LytR/CpsA/Psr (LCP) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY90971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12310"/>
    <dbReference type="EnsemblBacteria" id="AQP45487">
        <property type="protein sequence ID" value="AQP45487"/>
        <property type="gene ID" value="RPIT_12310"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY90971">
        <property type="protein sequence ID" value="SDY90971"/>
        <property type="gene ID" value="SAMN05428934_10614"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12310"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004474">
        <property type="entry name" value="LytR_CpsA_psr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03816">
        <property type="entry name" value="LytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00350">
        <property type="entry name" value="lytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="LytR_cpsA_psr" evidence="4">
        <location>
            <begin position="308"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="567"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="87"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="572"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY90971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="624" mass="66348" checksum="11D39A47305B0A30" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHJ4</accession>
    <name>A0A1Q2CHJ4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Polyphosphate:nucleotide phosphotransferase, PPK2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_12910</name>
        <name evidence="4" type="ORF">SAMN05428934_104105</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12910"/>
    <dbReference type="EnsemblBacteria" id="AQP45596">
        <property type="protein sequence ID" value="AQP45596"/>
        <property type="gene ID" value="RPIT_12910"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY77905">
        <property type="protein sequence ID" value="SDY77905"/>
        <property type="gene ID" value="SAMN05428934_104105"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12910"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016776">
        <property type="term" value="F:phosphotransferase activity, phosphate group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006797">
        <property type="term" value="P:polyphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022300">
        <property type="entry name" value="PPK2-rel_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022488">
        <property type="entry name" value="PPK2-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03976">
        <property type="entry name" value="PPK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03709">
        <property type="entry name" value="PPK2_rel_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPK2" evidence="2">
        <location>
            <begin position="36"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY77905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="394" mass="45123" checksum="53CE75680685AD7F" modified="2017-04-12" version="1">MTDFWTQDPRDALRVGPDFDLASFDRRGTPGWSGDKAAAKEAMAGRADLLNELQERLYAHGRAGGDKRILIVVQGLDTAGKGGIARHVMGLVDPQGVEMHSFGVPTEEEREHHYLWRIEKALPSVGKIGLFDRSHYEDVLVVRVDELVERDVWEKRYDEINEWEKNLVDEGYTILKFAMMVSKDEQSLRLMERIDRPDKRWKYSTGDLDTRSKWDAFQAAYADVFRLTSTDHAPWYVLPSDRKWYSRLAVTEILTRTLVDFDLHWPKPRWQPETQRRRLARAMSPEALAESLADTEAIVTEANDTSLAVRRAAALLRHEEQDQSVIDAALAEIEAKRQELAADLAATLEHKRGLLTEVAPELVPDVAGEDEQPKKKSKKKKSKKKDKKKKKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHJ6</accession>
    <name>A0A1Q2CHJ6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Monosaccharide ABC transporter ATP-binding protein, CUT2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_12835</name>
        <name evidence="6" type="ORF">SAMN05428934_104120</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY78284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12835"/>
    <dbReference type="EnsemblBacteria" id="AQP45581">
        <property type="protein sequence ID" value="AQP45581"/>
        <property type="gene ID" value="RPIT_12835"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY78284">
        <property type="protein sequence ID" value="SDY78284"/>
        <property type="gene ID" value="SAMN05428934_104120"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12835"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="9"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="263"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY78284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="511" mass="54641" checksum="EE116A0E64F6313A" modified="2017-04-12" version="1">MIDPDEVVLECEGLSKSYGRVRALDAVSLTLHKGEVRALLGKNGAGKSTLVKLLSGVEQPDKGAGEIRLAGQPVAWSSALAAQHGGITVVHQEFSLVPELSIAENITLGHWPSRGGLIDKAEIRRRASEAMAMLGVDLPLSRPVSRLSTAQQQLVEISKALSVQPKVLILDEPTSALNSNEVEVLLALLRRLASQGVSIIYVSHRMREIPQVADTLTVLRDGREVATRKVSDISAAEVARMIAGTDERARETVAKERLDEQTVSDEVVLAVEGLSIPGILENVNFELRRGEVLGFAGLLGSGRTELLEAIFGQRSDATGTVAVLGRQMTSRRPGKMLDAGVGMTTEDRKKTGIVPILSVSENMMLSARSRVVGGPLLDIAGERAASRSLVQKLRIQTSGLKQPIGTLSGGNQQKAVIGRCLAGNMKVLLLDEPTRGVDVDAKRQIYDLIRELADAGVSSVFVSSELEELSQVCDRVLVLRDGGVREELPGAEATSERLLALAMIGKEGHLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHJ9</accession>
    <name>A0A1Q2CHJ9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-2 type transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_12600</name>
        <name evidence="8" type="ORF">SAMN05428934_104166</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY79635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12600"/>
    <dbReference type="EnsemblBacteria" id="AQP45540">
        <property type="protein sequence ID" value="AQP45540"/>
        <property type="gene ID" value="RPIT_12600"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY79635">
        <property type="protein sequence ID" value="SDY79635"/>
        <property type="gene ID" value="SAMN05428934_104166"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12600"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY79635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="272" mass="28352" checksum="C260006E233BCC6A" modified="2017-04-12" version="1">MTALPTTTRADARHVSFPRVLRSEWIKLWSLRSTYWTVAATIAAMVFIAVLVGATSRIDDDAVAAGFDGTMAIGMGYTFAQVVVAVLGVLTITGEYSTGMIRSTLAAVPRRWPALAAKAVVVAVVGAALGLVGVAAAYAASYPLLGAAGAADLSDPEVQRIFWGTALYLAGVGLFGLAVGAVVRHSAGAITLVLGVLLMLSSFWQLLMVTSDWFARVYPYLPSVAGERIVSAAVEPGGPVDVLGPWAGFGVFMVYVVATMAAATALLRRRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHK3</accession>
    <name>A0A1Q2CHK3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ATP-binding cassette, subfamily B</fullName>
        </submittedName>
        <submittedName>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
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    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-0132">Cell division</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0946">Virion</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544517" evidence="4">
        <location>
            <begin position="25"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="73"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="5">
        <location>
            <begin position="243"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="6">
        <location>
            <begin position="391"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="32"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ13372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="495" mass="52972" checksum="AB79ED8939359A2F" modified="2017-04-12" version="1">MTALNRRHLLLGATGIAGAGLLSACTSPLNKPGTPAPGSGASRSYPAPSLAPAPGRSVVQQTLAPRPVTLDLGGLTAKTWAYDDSSMGVLRGTAGDLFRITVDNQLPASTSVHWHGVRLHHAADGVPGVTQDPIEPGTSFTYEFVAPDPGTFFFHPHSGVQLDRALYAPLIIDDPDEPGAYDDEWIVVLDDWTDGVGRGPDEIFEEFAAENGAVSMGMGHGNMRDMGHGASSPLGDAGDVEYPHYLINGRVPEAPATFEAKPGQRIRIRIINAASDTIFKLALGGHTMTVTHSDGFPVEPVDTAALYIAMGERYDVTVTLRDGTFPLAARPEGKTGTARAVVRTASGDAPSTDAPVPELDGDALLGTQLRAAAQARLPDGEPDDTFDVELNGQMDPYGWGINGRKFGDHEPLDVSPDRRVRMRMTNMTMMAHPMHIHGHTWGLPGSGGLRKDTVLLTPMQTIELDLITDNPGEWMLHCHNIYHAEVGMMTTMRYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHV8</accession>
    <name>A0A1Q2CHV8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_13450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45692">
        <property type="protein sequence ID" value="AQP45692"/>
        <property type="gene ID" value="RPIT_13450"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13450"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="155" mass="17795" checksum="A810606385883098" modified="2017-04-12" version="1">MTTRTVENHVNVPAAASDVWDRAVNPDGINFEMRPWMTMSMPPGAAGLSVEDIPLGQPVGRAWLRLFGLIPFDFDRLTIVELESGRRFLERSTMLSMRCWEHERTLTPVAGGTRVHDRVTFRPRLPIPGLAALLERVVDAFFRHRHRRLQEYFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHZ7</accession>
    <name>A0A1Q2CHZ7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glyco_trans_4-like_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_13810</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45748">
        <property type="protein sequence ID" value="AQP45748"/>
        <property type="gene ID" value="RPIT_13810"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13810"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="4">
        <location>
            <begin position="78"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="436" mass="47313" checksum="66CCEB338E8BB5A7" modified="2017-04-12" version="1">MLREPSEGELSMEAEIHEREAERGPRRGVLVLMPKDARTATGPVSVWLTAAGWAEAAQEAHGAAWMVTPSGILDGGEARLLATSAPRATLPPAAGWKRLIPTTLKTLRKDVLSWRHARSFREAGLEGPWEPEGPLWIWHHHEPFHDSGFVAKRRFGCPVVVFVDAPTVWESGQWGVKRPGWGRLLERFGEVAQLRDADLIACVTEEVANEVIRLGGPRERVIVTPTAVALDRFNEDVSGAEVRARYGLEGRTVVGWVGTFHKFHGLDLLVEAYAAVERERRDTSLLLVGDGQDRPRIEALVDSFGLRQVVFAGAVPQDQVPSHLAAMDVASVVDPGTGSFHYSPLKLKEYLACGRAVVAPASGQVARYVADGTHALLVPAGDAPALTRALLRLVDDPGLRSSLGAAGNALVRETGTWAHQLRTVEDALTSRGWVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI82</accession>
    <name>A0A1Q2CI82_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4397 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_14330</name>
        <name evidence="4" type="ORF">SAMN05428934_11248</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ15105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14330"/>
    <dbReference type="EnsemblBacteria" id="AQP45838">
        <property type="protein sequence ID" value="AQP45838"/>
        <property type="gene ID" value="RPIT_14330"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ15105">
        <property type="protein sequence ID" value="SDZ15105"/>
        <property type="gene ID" value="SAMN05428934_11248"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14330"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025510">
        <property type="entry name" value="DUF4397"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14344">
        <property type="entry name" value="DUF4397"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544527" description="DUF4397 domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4397" evidence="2">
        <location>
            <begin position="32"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ15105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="268" mass="26395" checksum="9ACDCC2D551792C8" modified="2017-04-12" version="1">MKLSRIIVAGSVALAASLGSASVAFADDHNTSNVSILHGVPGATVDVYVNGDALLTNFAPGTLTDPLELPEGSYDLKVVAPGAGADGEAIIEANDVAVPAGADITVVAHLTDAGVPALTPFVNDTSMSEEGGRLTVRHVAAAPAVDIRAGGAVAVSNLANPDEAKLDLAAGTVPADVVAAGTDTVVLGPADVTIAAGSNTIVYAWGSLEDENLALAIQNVALDTAGMPHTGAEGPANSTNGLVAATLLLAGVAVTVVMAQRNRAGNIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI84</accession>
    <name>A0A1Q2CI84_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LysM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_14250</name>
        <name evidence="5" type="ORF">SAMN05428934_11232</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ14797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14250"/>
    <dbReference type="EnsemblBacteria" id="AQP45822">
        <property type="protein sequence ID" value="AQP45822"/>
        <property type="gene ID" value="RPIT_14250"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ14797">
        <property type="protein sequence ID" value="SDZ14797"/>
        <property type="gene ID" value="SAMN05428934_11232"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14250"/>
    <dbReference type="Proteomes" id="UP000188324">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">RP1T</strain>
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    </reference>
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        <property type="term" value="F:nucleotide binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
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        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="5"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="130"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="329" mass="35140" checksum="82D12420390FF38F" modified="2017-04-12" version="1">MANLRAGLIGLGSMGRHHARNLRSIDGVDLVAVADPGGDPHGVAGSLEVLPDVEALIAQGVDYVVVATPTVYHEAIGLALADAGVHALIEKPLAADTGAARRLAEAFASKGLVGATGHIERYNPSLQSLRKRLEAGDLGDLYQITTRRQGPFPARIADVGVVKDLASHDVDLTAWVTQRKFELVAARTMSKAGRQYEDMVSATCQLEGGLMSNHLVNWLTPTKERLTVVTGEKGMFVADTLTADLTFYANGQVATTWDDIAQFRGVSEGDVTRFAISKPEPLRTEHEAFRDAVLGKDADIVTLEQGARVVEVCEAMIQSAKTGQFISVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIL6</accession>
    <name>A0A1Q2CIL6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptide chain release factor 3</fullName>
            <shortName evidence="5">RF-3</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">prfC</name>
        <name evidence="7" type="ORF">RPIT_14780</name>
        <name evidence="8" type="ORF">SAMN05428934_10964</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14780"/>
    <dbReference type="EnsemblBacteria" id="AQP45913">
        <property type="protein sequence ID" value="AQP45913"/>
        <property type="gene ID" value="RPIT_14780"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05796">
        <property type="protein sequence ID" value="SDZ05796"/>
        <property type="gene ID" value="SAMN05428934_10964"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14780"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006449">
        <property type="term" value="P:regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00072">
        <property type="entry name" value="Rel_fac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004548">
        <property type="entry name" value="PrfC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032090">
        <property type="entry name" value="RF3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038467">
        <property type="entry name" value="RF3_dom_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43556">
        <property type="entry name" value="PTHR43556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16658">
        <property type="entry name" value="RF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00503">
        <property type="entry name" value="prfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="6">
        <location>
            <begin position="14"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="91"/>
            <end position="95"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ05796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="532" mass="58624" checksum="F8A01541A4FB25DD" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIP7</accession>
    <name>A0A1Q2CIP7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Geranylgeranyl pyrophosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_02700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02700"/>
    <dbReference type="EnsemblBacteria" id="AQP45982">
        <property type="protein sequence ID" value="AQP45982"/>
        <property type="gene ID" value="RPIT_02700"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02700"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="310" mass="33013" checksum="53CFF6EB462BD5A0" modified="2017-04-12" version="1">MLLETFEEQLVTAAVADSPFVTEAARHLVAAGGKRFRPLLVFLASRFGAGATEGDLMRAAMVMELTHVASLYHDDVMDDADLRRGAPSSNRLWGNSVAILVGDFLFARASTQVAELGVEYVKLQAETFARLVQGQIAETKGPGELEDPLAHYIQVIADKTGSLIAASALFGGMVAGADRQTLDALAAFGEEVGLVFQLSDDLIDITSETTGKTPGTDLREGVPTLPVLMLRAENNPADAELLALIDGDLASDEALARALEGLSAHPVMQRAKAEVERRAEIARGHLDPLPDGEAKDALLRVCADLVDRTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIQ7</accession>
    <name>A0A1Q2CIQ7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peripla_BP_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03300"/>
    <dbReference type="EnsemblBacteria" id="AQP45992">
        <property type="protein sequence ID" value="AQP45992"/>
        <property type="gene ID" value="RPIT_03300"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03300"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peripla_BP_4" evidence="1">
        <location>
            <begin position="11"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="278" mass="29325" checksum="372AC6998E0A9E9F" modified="2017-04-12" version="1">MKIGVTFPILDQFLQNVADGIEARAEEAGVEVTIVSAQEKADTQLGQVENFISQGVQGIIVIPVDTDAAGPMTEKAMDADIPLAYVNRRPADLPAGVPYVGSDSLVSGILEMEALAELAGGKGKVGILQGDPANEAARLRTQGCKDVVAEYPDMEVVREQAGNWYREKGLQITENWIQSGDEIDIICANNDEMALGAIQALKNADMLDDVLVGGVDATADALAAMEAGELEVTVFQDAAGQGAGGVDAIINMYNGDETPAVIDVPYQLVTPENMADFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIS8</accession>
    <name>A0A1Q2CIS8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ca-activated chloride channel family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Magnesium chelatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05170</name>
        <name evidence="4" type="ORF">SAMN05428934_101640</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY40436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05170"/>
    <dbReference type="EnsemblBacteria" id="AQP46029">
        <property type="protein sequence ID" value="AQP46029"/>
        <property type="gene ID" value="RPIT_05170"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY40436">
        <property type="protein sequence ID" value="SDY40436"/>
        <property type="gene ID" value="SAMN05428934_101640"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05170"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024163">
        <property type="entry name" value="Aerotolerance_reg_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07584">
        <property type="entry name" value="BatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="92"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY40436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="322" mass="34238" checksum="378C2C10537F3A1A" modified="2017-04-12" version="1">MWGWVPEFQNPERLWWLLLLPALIVIYLILLRLKGRVALRFTNTGVLGRVVGSQRRWTRHLAVAMSLCSLVALALAYANPLGTEKQPRERATVVMVIDVSLSMSADDVAPNRLSAAKQAATDFVQGLPTSYNVAVVSMSGSPSIVAPPLTDRGAIERAIGAMELSDGTAIGESITSALRAVDQAPAGDDEDEPAPAMIVMLSDGTNTEGPEPAAAAAAAAERDVPIYTIAYGTQNGFVDIDGQRENVAPDVEALREIARATGGESVQADDVASLNDAYRDIGSVVGYEEVRKPITAQYAFFALGFAVVAALGAVMMAARWPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIT3</accession>
    <name>A0A1Q2CIT3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endolytic murein transglycosylase</fullName>
            <ecNumber evidence="7">4.2.2.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Peptidoglycan polymerization terminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mltG</name>
        <name evidence="8" type="ORF">RPIT_06225</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the transglycosylase MltG family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.-" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06225"/>
    <dbReference type="EnsemblBacteria" id="AQP46048">
        <property type="protein sequence ID" value="AQP46048"/>
        <property type="gene ID" value="RPIT_06225"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06225"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008932">
        <property type="term" value="F:lytic endotransglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08010">
        <property type="entry name" value="MltG_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02065">
        <property type="entry name" value="MltG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003770">
        <property type="entry name" value="MLTG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30518">
        <property type="entry name" value="PTHR30518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02618">
        <property type="entry name" value="YceG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00247">
        <property type="entry name" value="TIGR00247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="7">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP46048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="367" mass="39989" checksum="9196FC4633CA6D3B" modified="2017-04-12" version="1">MDNDGRLDWRKVGYHARSAFAVLLSLSIIIGGGWFVYDRANDAYVAWRTADDYAGEGTGEEVQVLIPRGAGVNQIGDILVEAGVVKSIKAFRKAAQESGESDQLSYGRFNLTKELPAQTAFEMLLDPENMVVLTVTFPEGTPNSQQWDIITRDLEVPADAIAAAAANIDYFDLPEYAEGNLEGFLFPSTYNVAEPPNPSWIMASQVRQFKTVAERLSLEGRAEELGYTPLEVVTIASIVAREVSTPTDQPMVAGVIYNRLAQGMKLQMDSTVHYALGKYGKVTTTAEDRANPSPYNTYYHEGLPPAPISNPGLTALEAAITPATTDALFFVTVDLDTGETRFAATAEEHAANVALFQQWCQANTGRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIU5</accession>
    <name>A0A1Q2CIU5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_04840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP46024">
        <property type="protein sequence ID" value="AQP46024"/>
        <property type="gene ID" value="RPIT_04840"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04840"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011958799" evidence="2">
        <location>
            <begin position="36"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="236" mass="26154" checksum="3E740D27A5B4FEB8" modified="2017-04-12" version="1">MPEARTVVRAILLVTLMGSIVFASVRLATAPAASADPSVRVQSDYVLMLLQCALGIVVMFLPLIVQRRFAVHLPSAIEIAFFVFLYCAIYLGEVRSFYFRIPYWDNVLHFFSGAMLGALGFVLVQLLNDSQRLHVELSPAFVSFFAFCFALASGVVWEIYEFTADSLLGTNMQKYVTEAGEVLIGRSALHDTMIDLIIDASAALIVTVLGFLWLRPRMGKDAERPAPLLERRPAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ14</accession>
    <name>A0A1Q2CJ14_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_05830</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05830"/>
    <dbReference type="EnsemblBacteria" id="AQP46040">
        <property type="protein sequence ID" value="AQP46040"/>
        <property type="gene ID" value="RPIT_05830"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05830"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
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    <keyword evidence="4" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
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        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
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            <begin position="137"/>
            <end position="162"/>
        </location>
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        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
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        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
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        <location>
            <begin position="46"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP46040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="277" mass="29784" checksum="48561EFAF5EBEB0E" modified="2017-04-12" version="1">MAGVAVFYYYPIVANAWTSLTSSNAFGQNPEFVGVDNYAEVFASGELGSALGNTIGYTLIVLLGIPLAVLASALIALPGLRFAGLYRALFFMPYLAMPMAIAQVFRLVFNGDFGLVNQGLRALGVSTTPYWLTTPGFALLTVALFGLWASIGFNVIILSAGLKGIPVDLYEAASLDGAGPIRQFFSITVPLLTPSIFFLTIIQTINGFQLFDALFALMGWTNPALPQTRSLVYLFYHQGFIVNDKGTAAAVAMVILVLVAGVTLVQFVGQRRWVHYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
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        <recommendedName>
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        </recommendedName>
    </protein>
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    </gene>
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        <name type="scientific">Tessaracoccus flavus</name>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10630"/>
    <dbReference type="EnsemblBacteria" id="AQP46126">
        <property type="protein sequence ID" value="AQP46126"/>
        <property type="gene ID" value="RPIT_10630"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10630"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
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    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP46126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="145" mass="15814" checksum="493B6B425D469712" modified="2017-04-12" version="1">MGAYALVVSQRGILGTVNSRLTGAPGTWALPGGGVDPDESPADAVLREIYEETGQEVVLDRVLSLESEHWVGRSLAGRLEDFHALRVVYGAICKTPSDPVVHDVGGSTERADWVPARAWRKLHWTNSSRNLLAQYARKLSRPISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ73</accession>
    <name>A0A1Q2CJ73_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ribonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_08730</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08730"/>
    <dbReference type="EnsemblBacteria" id="AQP46095">
        <property type="protein sequence ID" value="AQP46095"/>
        <property type="gene ID" value="RPIT_08730"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08730"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006847">
        <property type="entry name" value="IF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019307">
        <property type="entry name" value="RNA-bd_AU-1/RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004659">
        <property type="entry name" value="RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30001">
        <property type="entry name" value="PTHR30001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04760">
        <property type="entry name" value="IF2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10150">
        <property type="entry name" value="RNase_E_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00757">
        <property type="entry name" value="RNaseEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="9">
        <location>
            <begin position="497"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="92"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="875"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="113"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="207"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="301"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="347"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="422"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP46095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="899" mass="98141" checksum="A748A32622BB5E4A" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ94</accession>
    <name>A0A1Q2CJ94_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thiosulfate sulfurtransferase</fullName>
            <ecNumber evidence="2">2.8.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_12440</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>hydrogen cyanide + thiosulfate = 2 H(+) + sulfite + thiocyanate</text>
            <dbReference type="Rhea" id="RHEA:16881"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:18022"/>
            <dbReference type="ChEBI" id="CHEBI:18407"/>
            <dbReference type="ChEBI" id="CHEBI:33542"/>
            <dbReference type="EC" id="2.8.1.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.8.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP46153">
        <property type="protein sequence ID" value="AQP46153"/>
        <property type="gene ID" value="RPIT_12440"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12440"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001307">
        <property type="entry name" value="Thiosulphate_STrfase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00380">
        <property type="entry name" value="RHODANESE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="2"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP46153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="91" mass="9644" checksum="A3BD9D6213C71D9B" modified="2017-04-12" version="1">MAKEGTVILDVRTPEEFAAGHIPGAINLDVQSPTFADDVASLDNAVPYAVYCRSGNRSQVALDIMTERGFEAFHLAGGIGAWQSAGYDIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ95</accession>
    <name>A0A1Q2CJ95_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 14">Inosine-5'-monophosphate dehydrogenase</fullName>
            <shortName evidence="7">IMP dehydrogenase</shortName>
            <shortName evidence="7">IMPD</shortName>
            <shortName evidence="7">IMPDH</shortName>
            <ecNumber evidence="7 14">1.1.1.205</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">guaB</name>
        <name evidence="16" type="ORF">RPIT_09955</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 14">
            <text>H2O + IMP + NAD(+) = H(+) + NADH + XMP</text>
            <dbReference type="Rhea" id="RHEA:11708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="1.1.1.205"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="7">Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 14">Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 13">Belongs to the IMPDH/GMPR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.205" evidence="7 14"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09955"/>
    <dbReference type="EnsemblBacteria" id="AQP46115">
        <property type="protein sequence ID" value="AQP46115"/>
        <property type="gene ID" value="RPIT_09955"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09955"/>
    <dbReference type="UniPathway" id="UPA00601">
        <property type="reaction ID" value="UER00295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006177">
        <property type="term" value="P:GMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00381">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01964">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005990">
        <property type="entry name" value="IMP_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015875">
        <property type="entry name" value="IMP_DH/GMP_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911">
        <property type="entry name" value="PTHR11911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000130">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01302">
        <property type="entry name" value="IMP_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00487">
        <property type="entry name" value="IMP_DH_GMP_RED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0129">CBS domain</keyword>
    <keyword evidence="3 7 14" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="2 7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 14" id="KW-0520">NAD</keyword>
    <keyword evidence="5 7 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="7 14" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="15">
        <location>
            <begin position="99"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="15">
        <location>
            <begin position="159"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7 9">
        <location>
            <begin position="345"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7 9">
        <location>
            <begin position="368"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7 9">
        <location>
            <begin position="392"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimidate intermediate" evidence="7 8">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 8">
        <location>
            <position position="414"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="253"/>
            <end position="255"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <begin position="305"/>
            <end position="307"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 11">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 11">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 11">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="429"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="483"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="484"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="485"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="AQP46115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="501" mass="52876" checksum="FB8467C242DE8FFD" modified="2017-04-12" version="1">MTGAGVPRPFAALGLTFDDVLLQPNQSDIIPSEVDTGTQLTKRIRLNVPLVSAAMDTVTESRMAISMAREGGIGILHRNLSIEQQAHMVDQVKRSEAGMVSEPVTVSPDATLAEVDEMCSQYRISGAPVIDANGVLVGIITNRDMRFEDDGNRSVGDVMTKMPLVTVREGASGEEALGLMAKHKVEKIPIVDGQNRLKGLITLKDFVKADRYPNAAKDDQGRLRVGAGVGFYGDSWERAMALVEEGVDLIVVDTAHGHSRGVVEMIKRLKAEPLAKDVDIVGGNVATYAGAKALVEAGADAVKVGVGPGSICTTRVVAGVGVPQVTAIFDAAQAARPAGVPVIGDGGLQYSGDIAKAIVAGASAVMLGSLLAGCEESPGDLVFINGKQFKSYRGMGSLGAMAARGRKASYSKDRYFQGDVTSDDKLIPEGIEGQVAYRGPLAAVAYQLVGGLRQSMFYSGASTIAELQDRGRFVRITAAGLRESHPHDIQLTAEAPNYWAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJA3</accession>
    <name>A0A1Q2CJA3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DAC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_10605</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 ATP = 3',3'-c-di-AMP + 2 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:35655"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:71500"/>
            <dbReference type="EC" id="2.7.7.85"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10605"/>
    <dbReference type="EnsemblBacteria" id="AQP46125">
        <property type="protein sequence ID" value="AQP46125"/>
        <property type="gene ID" value="RPIT_10605"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10605"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106408">
        <property type="term" value="F:diadenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036888">
        <property type="entry name" value="DNA_integrity_DisA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003390">
        <property type="entry name" value="DNA_integrity_scan_DisA_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143597">
        <property type="entry name" value="SSF143597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51794">
        <property type="entry name" value="DAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAC" evidence="6">
        <location>
            <begin position="345"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP46125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="580" mass="63147" checksum="96F3DBFAC961E3AC" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBK1</accession>
    <name>A0A1Q2CBK1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="4 7">1.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_00495</name>
        <name evidence="13" type="ORF">SAMN05428934_10552</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H2O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate</text>
            <dbReference type="Rhea" id="RHEA:23596"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="1.1.1.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="4 7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY84818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00495"/>
    <dbReference type="EnsemblBacteria" id="AQP43482">
        <property type="protein sequence ID" value="AQP43482"/>
        <property type="gene ID" value="RPIT_00495"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY84818">
        <property type="protein sequence ID" value="SDY84818"/>
        <property type="gene ID" value="SAMN05428934_10552"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00495"/>
    <dbReference type="UniPathway" id="UPA00038">
        <property type="reaction ID" value="UER00491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006065">
        <property type="term" value="P:UDP-glucuronate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028357">
        <property type="entry name" value="UDPglc_DH_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500134">
        <property type="entry name" value="UDPglc_DH_bac"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 10" id="KW-0520">NAD</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="11">
        <location>
            <begin position="300"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="142"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="242"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
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            <dbReference type="PIRSR" id="PIRSR500134-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
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    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP43482.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY84818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="388" mass="42728" checksum="2A2B5C510838C57B" modified="2017-04-12" version="1">MKIGVVGLGYVGAAMSVLLAVRHEVRAVDISASRVQAIEARRAPIADPELQHHLDTQPLTLTATTDPAEALPGCDFVIVATPTNYDPELDFFDTSTVESVIEDVKRLAPESTVVIKSTIPVGFTARMQREHPDLTILFSPEFLREGRALYDNLHPSRIVVAGDGPRASEFAELLRDSAEDREVPVLITGTAEAEAIKLFANTYLAMRVAYFNELDTFAANHGLNTRDIIEGVGHDPRIGNFYNNPSFGYGGYCLPKDTQQLLANYRDVPQNLIRAIVDSNRTRMDFIARDILALGPETVGVYRLAMKAGSDNFRESSIQGVLARLRAAGVDVIVHEPLLRTDEFVGCEVVNDVAEFKRRSDVIVTNRRAPELGDVQGKVYTRDLYGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBL2</accession>
    <name>A0A1Q2CBL2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UDP-N-acetyl-D-mannosamine dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_00550</name>
        <name evidence="6" type="ORF">SAMN05428934_10563</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY85095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00550"/>
    <dbReference type="EnsemblBacteria" id="AQP43492">
        <property type="protein sequence ID" value="AQP43492"/>
        <property type="gene ID" value="RPIT_00550"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY85095">
        <property type="protein sequence ID" value="SDY85095"/>
        <property type="gene ID" value="SAMN05428934_10563"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00550"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028359">
        <property type="entry name" value="UDP_ManNAc/GlcNAc_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500136">
        <property type="entry name" value="UDP_ManNAc_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="4">
        <location>
            <begin position="309"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY85095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="408" mass="43430" checksum="9DB1985A173364BD" modified="2017-04-12" version="1">MSQPDVCVVGLGYIGLPTAAIFAHKGLRVHGVDVSPRTVDAINAGKVPFVEPDLGGYVQRAVAAGKLTASGDPVPAKAFIIAVPTPFKDGHEADLSYIESATRAVAPHLSGNELLILESTSPPGATEFMASIVAEERPELADADLKFAHCPERVLPGRVMVELVINDRIVGGLTPEAAQVAAELYRVFCEGEILLTDAKTAEMAKLVENSFRDVNIAFANELSVIADEHGIDVWELIELANHHPRVNILQPGPGVGGHCIAVDPWFIVSSTPTLSNLIRTAREVNDAKPDFVMDKVKAAIDGVDSPKIAALGLAFKPNIDDLRESPALAITERLSAELPGAQILAVEPHVDELPAKLAGHPNVSLVATEAAVREADVVLVLVDHTAFKSLDRSLLEGKTLIDTRGLYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBN1</accession>
    <name>A0A1Q2CBN1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_00660</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00660"/>
    <dbReference type="EnsemblBacteria" id="AQP43511">
        <property type="protein sequence ID" value="AQP43511"/>
        <property type="gene ID" value="RPIT_00660"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00660"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="DUF304"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014529">
        <property type="entry name" value="UCP026631"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03703">
        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
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        <location>
            <begin position="211"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="3">
        <location>
            <begin position="84"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="3">
        <location>
            <begin position="265"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="3">
        <location>
            <begin position="384"/>
            <end position="451"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="468" mass="50425" checksum="C691C108E6787DB1" modified="2017-04-12" version="1">MATDQPSTSTSPESAPTPAEKVVERPSPLTGIAHSGIVLAGSVVLFVREISENGLSDLTGMAVVVGVIALGSALIAFGAGIAAWRTTTFIVDDEEFRVERKFLWTSSSRVDYTKVQSVEINQPFIARLLGLAKVQIDVGGAGGVALSFLTLSRAEALREHMLARMRRARAVTPVGTPQGPAVPDGEAASGPPETALAEEPEVLVHAVPVHILFLGTLVSSTAFSLGTAALILLALYIWQDTGFTVLGALVAVAGWLWANIGSNWGFTVTRRGDTLRVRRGLTSTATQGLRPERIQGISIRQDLFQRLTGLYRVRVNVLGMAGQSGDDGKVDTSVLLPFGSWDDVLKILHVVWPHVDLSEIQPHPQPGRARWLTPLSHSEHTWGVGRDVVVAHHGLIEHTLTIVPHVRMQSLSLHQGPLQRRLRLASVALHTTDGPVSCRLYHLDEHTARQVFFEQLERAQAARSAAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBQ4</accession>
    <name>A0A1Q2CBQ4_9ACTN</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="4" type="ORF">SAMN05428934_105121</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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        </lineage>
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    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY86634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43543">
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        <property type="gene ID" value="RPIT_00840"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86634">
        <property type="protein sequence ID" value="SDY86634"/>
        <property type="gene ID" value="SAMN05428934_105121"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00840"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544406" evidence="2">
        <location>
            <begin position="27"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY86634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="196" mass="20422" checksum="33DF29D128D24C9F" modified="2017-04-12" version="1">MQLSSRSILPFLAAAALALSACGGEAEVPPTPATEAASTTTPEPVPEPTDEAPATGSDDGAIEMEEEMEEIAASMEAQQTGGSASVTIGDQTWDFDGVLCAFGPEEIGQEGAEFVLSAIGDGLQFYISVDAMGQFVSLNDIENFEDPALSWEADQDASGEGFIQVDGKDVSGEATFIDYLSESWDEVEGSFEGSCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBS1</accession>
    <name>A0A1Q2CBS1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00565</name>
        <name evidence="3" type="ORF">SAMN05428934_10567</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY85197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43495">
        <property type="protein sequence ID" value="AQP43495"/>
        <property type="gene ID" value="RPIT_00565"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY85197">
        <property type="protein sequence ID" value="SDY85197"/>
        <property type="gene ID" value="SAMN05428934_10567"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00565"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY85197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="165" mass="17480" checksum="4E1823F6D07759E7" modified="2017-04-12" version="1">MDERQELNAGRAAMIVLAVLMIGCVAVLGWEYLRTQEVTNTAAIVVMLGAGGLFVLIQRMFGAEAPRTFLGQELPTGPSAPERAERRRAYAVDAGLFAVAMTVLTFGGILLGDASDLLPIEGPLGLALLAALELVGGFAIFYAFNWVLGESAARGVEKKLARLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBS8</accession>
    <name>A0A1Q2CBS8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NERD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00955</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00955"/>
    <dbReference type="EnsemblBacteria" id="AQP43564">
        <property type="protein sequence ID" value="AQP43564"/>
        <property type="gene ID" value="RPIT_00955"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00955"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011528">
        <property type="entry name" value="NERD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08378">
        <property type="entry name" value="NERD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50965">
        <property type="entry name" value="NERD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NERD" evidence="2">
        <location>
            <begin position="16"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="106" mass="12038" checksum="932037825CDD8F2F" modified="2017-04-12" version="1">MVDDRWIEVTPSQFAHEADGLRIVRDLLPKRAPFRAWTNFEFRDDRGNWSEVDLLILAPDGLHLVELKYYSGRLRGNDQTWLRDGRAAEDSPSASPTARPSACAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBV5</accession>
    <name>A0A1Q2CBV5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00735</name>
        <name evidence="3" type="ORF">SAMN05428934_105100</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43525">
        <property type="protein sequence ID" value="AQP43525"/>
        <property type="gene ID" value="RPIT_00735"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86096">
        <property type="protein sequence ID" value="SDY86096"/>
        <property type="gene ID" value="SAMN05428934_105100"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00735"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY86096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="191" mass="21036" checksum="019C229F060F4017" modified="2017-04-12" version="1">MTEPKQIATLPPNEEIRQEVPRSPRTGEPPRPVLVAIAAVALYLAAAALAVVYGIRWWEAAHPETYPTSARLLEWVQPEPGRWLSLALEGVFAGALVLAAGACGVVGFQAWNGWRWSRWAGLVALGFVGGFVAIVDDWAFVGLGLAAIGVTLLFLPPVTRYFQRWAAVRAEQPAPYRRPSQIHYGRLPRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBY4</accession>
    <name>A0A1Q2CBY4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS110 family transposase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01255</name>
        <name evidence="3" type="ORF">RPIT_12380</name>
        <name evidence="4" type="ORF">SAMN05428934_1311</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000031">
        <property type="protein sequence ID" value="SDZ24307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43612">
        <property type="protein sequence ID" value="AQP43612"/>
        <property type="gene ID" value="RPIT_01255"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45500">
        <property type="protein sequence ID" value="AQP45500"/>
        <property type="gene ID" value="RPIT_12380"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ24307">
        <property type="protein sequence ID" value="SDZ24307"/>
        <property type="gene ID" value="SAMN05428934_1311"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01255"/>
    <dbReference type="KEGG" id="tfl:RPIT_12380"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="1">
        <location>
            <begin position="9"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ24307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="425" mass="46398" checksum="49D72F278CB351BF" modified="2017-04-12" version="1">MDVVHQRCAGMDVSKSDAKVCVRVQGRGSRRTSTEITTWPARASSILELGQYLVREKVSCVVMEATSDYWKPFFYLLSEAGLSVVLANPRQVRQIPGRKTDVADAAWLADLAAHGLVRGSFVPGQAQREIKDLVRHRTQLVRLSGQEIQRLEKLLESASIKLSSVISDINGVSGRRMLQALIEGERDPQVLAGLGCRLKASTDELAEALTGRFTEHHGFLARLHLHLIDDYAAQISELDARIEGYFTDNDPAPEGAMTWGKARALLSTIPGVSDTTAEQILAEIGIDMSVFDSPGKLASWAGVAPGLNESAGKRHSSTCRPGNKHLKGALGMAALSAANSKHTFLAARFRRLTRRGSQRAVVALSRTLITICWHILTTGEPYHELGADYYDKRRPGVAIRNALNHLRQAGLTITPTPEGLLLTQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC20</accession>
    <name>A0A1Q2CC20_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA polymerase III subunit delta</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">DNA polymerase-3 subunit delta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_01475</name>
        <name evidence="2" type="ORF">SAMN05428934_10843</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01475"/>
    <dbReference type="EnsemblBacteria" id="AQP43647">
        <property type="protein sequence ID" value="AQP43647"/>
        <property type="gene ID" value="RPIT_01475"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01763">
        <property type="protein sequence ID" value="SDZ01763"/>
        <property type="gene ID" value="SAMN05428934_10843"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01475"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ01763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="383" mass="40921" checksum="E5CE806FF7D39582" modified="2017-04-12" version="1">MGDVWSELIGQERAVATLRRAVDGKSHAMSHAWLFVGPPGSGRSNAARAFAAALQCPRGGCGECEECRTTLSAAHPDVTLLRTEQLSIGVDEVRALVGRANMSPVKQRYQIVVVEDADRITERGADALLKGLEEPAARTVWLLCAPSADDVIVTIRSRCREIKLVTPSDDAVTELLVSRDGISPALAAHAARAAQGHVGRARMLARSEEARIRRREILALPGRLTSVTACLDAAENLVSSAADEAAQATAELDARELASLQAAMGLGGRGAKPRNAQAAVRELEDQQKARVKRIQRDALDRVLTELTGYYRDVLAAQTAPGVPLVNSDLADEIEPFARQTRPEHTVRALDAILQARTALEGNVAPLLALESLLIGLAAARKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC92</accession>
    <name>A0A1Q2CC92_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_01980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01980"/>
    <dbReference type="EnsemblBacteria" id="AQP43729">
        <property type="protein sequence ID" value="AQP43729"/>
        <property type="gene ID" value="RPIT_01980"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01980"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="281" mass="29555" checksum="E16FFAB3B90F9200" modified="2017-04-12" version="1">MATRMLALLDGSLVDPSTPIVRADDDGVVRGDGVFDALLAANGIARDLDEHLGRLADSAKILALPAPDEAGYRRAVDAVLQAWDWQAEPEAVLRLIQTRGPAGGQGNGYVLAAPLDAATRRERYEGVRVLLLDRGFEGNGIVDLPWLLPGAKSLSYGINMAAKRYAIANGADDVIFVTPSGAILEGPTSSVVLDLDGVLHTPPLDGILRSITIAELLEKAPAAGLEVKVGALTVDDLWRARGAWLLSSGRLIASVNEADGKPLPASPLDGALRRILDVPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCG8</accession>
    <name>A0A1Q2CCG8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02395</name>
        <name evidence="3" type="ORF">SAMN05428934_10177</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY24600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02395"/>
    <dbReference type="EnsemblBacteria" id="AQP43809">
        <property type="protein sequence ID" value="AQP43809"/>
        <property type="gene ID" value="RPIT_02395"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY24600">
        <property type="protein sequence ID" value="SDY24600"/>
        <property type="gene ID" value="SAMN05428934_10177"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02395"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY24600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="311" mass="32596" checksum="C5E6BD5A47F64721" modified="2017-04-12" version="1">MGHIVASVLPIILLIGLGWLLRATRVLSDAGVDTLKTLVVNVVLPAVLFNAFLGIEFQAEYLAIIILVPLVCLALLALGYVAKRVLPSSSEVTPFLFTGFEFGMVGLALFTAAYGLENVPVAGMVGLGHEFFIWFVFVTLLRRATTGAVSAGEALRSFATSPVIIAIALGLLLNVTGVGGPLGETAVGGALLVATQYLAATIVPIILIVVGHGTRLGAAGVRQAAPLVAARFAVVLSLALLLNYVVIRQWLGLPPIVEAALFTLLILPPPYIVPIFLPKHRAADMTYANNVLSLHTVVSVAAFITYVALTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCH0</accession>
    <name>A0A1Q2CCH0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02250"/>
    <dbReference type="EnsemblBacteria" id="AQP43780">
        <property type="protein sequence ID" value="AQP43780"/>
        <property type="gene ID" value="RPIT_02250"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02250"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012162221" evidence="1">
        <location>
            <begin position="26"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="118" mass="12513" checksum="32FDB52F70482678" modified="2017-04-12" version="1">MVRGLWLAVSVALITGLGVASPARADDPEDTPPAADVVVRPDWVSASVTARASGVRVEVLSERSETTQVFVNADGTVVEETAFAPVRFRDEAGSEGWREIDTTLVAAGDGSVSRCRWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCI0</accession>
    <name>A0A1Q2CCI0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43790">
        <property type="protein sequence ID" value="AQP43790"/>
        <property type="gene ID" value="RPIT_02300"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02300"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006120">
        <property type="entry name" value="Resolvase_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02796">
        <property type="entry name" value="HTH_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="111"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="417" mass="45472" checksum="0EDD77DD38FAB18B" modified="2017-04-12" version="1">MISVEDWAEIRRLHKSEKMAIKAIARQLGVARNTVRAALSSDGPPKYERVPAGSVVDEFEPQIRALLSKTPTMPATVIAERIGWTRSPSVLRAKVAELRPLFAPSDPADRTEYRPGEVVQCDLWFPPKVVRVAADVWTAPPVLTMVAAWSGFIAAVLLPSRTTGDLLAGMWQLLSGSFGGVPKTLVWDNEAGIGQHRRLTVAARAFAGTLGTQIYQTRPRDPEAKGVVERANGFLQTSFLPGREFGSPAEFNTQLGAWLPRANQRLLRRTGAAPAARLAAEVAAMTALPPVPPAVGFSDRIRLGRDYYVRVMGNDYSVDPTMIGRFVDITCSLEHVTVRCAGTVVALHERCWDLRRTITDPTHVAAAKQLRAAFQSRTTPTPGRAEPSQQVGLRPLSDYDALFNLKAAPAQSVKEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCJ3</accession>
    <name>A0A1Q2CCJ3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Molybdopterin molybdenumtransferase</fullName>
            <ecNumber evidence="7">2.10.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_02170</name>
        <name evidence="10" type="ORF">SAMN05428934_10132</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo-molybdopterin</text>
            <dbReference type="Rhea" id="RHEA:35047"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.10.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the MoeA family.</text>
    </comment>
    <dbReference type="EC" id="2.10.1.1" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY23261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02170"/>
    <dbReference type="EnsemblBacteria" id="AQP43765">
        <property type="protein sequence ID" value="AQP43765"/>
        <property type="gene ID" value="RPIT_02170"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY23261">
        <property type="protein sequence ID" value="SDY23261"/>
        <property type="gene ID" value="SAMN05428934_10132"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02170"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061599">
        <property type="term" value="F:molybdopterin molybdotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032324">
        <property type="term" value="P:molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00887">
        <property type="entry name" value="MoeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038987">
        <property type="entry name" value="MoeA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005111">
        <property type="entry name" value="MoeA_C_domain_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036688">
        <property type="entry name" value="MoeA_C_domain_IV_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005110">
        <property type="entry name" value="MoeA_linker/N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036135">
        <property type="entry name" value="MoeA_linker/N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192">
        <property type="entry name" value="PTHR10192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03454">
        <property type="entry name" value="MoeA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03453">
        <property type="entry name" value="MoeA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63867">
        <property type="entry name" value="SSF63867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63882">
        <property type="entry name" value="SSF63882"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6 7" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="8">
        <location>
            <begin position="180"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP43765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY23261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="402" mass="41045" checksum="030F581BC1C3B3CA" modified="2017-04-12" version="1">MRTVEEQRARILSLAEPLAAEVTPIVSAVGGVLAEDLPARFAVPPFDNSAMDGFAVRAGDLAAGVELVVVGDIPAGATSVPEVGEGQCARIMTGAPLPPGADAVVPVELTDQPWGQAELPARMRITEAVAVGKHVRRKGENVRVGEPGLPAGLAWSPAAASSAASLGYAEVPLIRRPRVAVLSTGSELVAPGEPLGFGQIPDSNSVLLAGLCRQFGAEVISARAVGDDPAQFRAALDVALAADLVVTTGGVSVGAFEVVRQVTEGQIEFTKVAMQPGKPQASGVLAAPDGRKVPMLGLPGNPVSAFVSAWVFVRPLIACLAGRADRWPSVQARAAVGWSTPPGRRQYVPVAVADGLATPVHALGSGSHLVATLALADGLAVVPEDVEQVQPGDLLTVHSITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCY8</accession>
    <name>A0A1Q2CCY8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha-1,6-mannosyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_03400</name>
        <name evidence="5" type="ORF">SAMN05428934_101280</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03400"/>
    <dbReference type="EnsemblBacteria" id="AQP43979">
        <property type="protein sequence ID" value="AQP43979"/>
        <property type="gene ID" value="RPIT_03400"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30743">
        <property type="protein sequence ID" value="SDY30743"/>
        <property type="gene ID" value="SAMN05428934_101280"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03400"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="3">
        <location>
            <begin position="15"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY30743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="380" mass="41340" checksum="740B97D726E4C714" modified="2017-04-12" version="1">MRIAQLANFVGPTSGGMKVVIENLGKGYVEAGHERVFVAPGVRDEVIETESGILVYVRAPRVTDQYRMIFKPWRALDALDRFRPTTVEVSDKWTLSPAAGWAARRGVGSILFSHERLSDMLAMWARQSFGVEVAVGALNRRLSKAFEAVVVTSEFAAEEFAGTGARLELVPLGVDLETFRPEVGAPADDGVLKLCYVGRLSHEKSPQLAVGTAVELHRRGHLVRLDMYGTGPDEAMLREAAGDVEVVFHGFVAGRDEVAKRYAAADISLSVCPAETFGLAVLEALACGTPVVTSNRGGARELVDHTSGASADPHPAALADAVEELLPRLGADFRAAARRRAERYSWSRTTQRMLALHEELARTVAFRVPRSGPKREGRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD14</accession>
    <name>A0A1Q2CD14_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmJ</name>
        <name evidence="6" type="ORF">RPIT_03350</name>
        <name evidence="7" type="ORF">SAMN05428934_101270</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL36 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_002514836.1">
        <property type="nucleotide sequence ID" value="NZ_FNPU01000001.1"/>
    </dbReference>
    <dbReference type="SMR" id="A0A1Q2CD14"/>
    <dbReference type="STRING" id="1610493.RPIT_03350"/>
    <dbReference type="EnsemblBacteria" id="AQP43970">
        <property type="protein sequence ID" value="AQP43970"/>
        <property type="gene ID" value="RPIT_03350"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30435">
        <property type="protein sequence ID" value="SDY30435"/>
        <property type="gene ID" value="SAMN05428934_101270"/>
    </dbReference>
    <dbReference type="GeneID" id="29844025"/>
    <dbReference type="GeneID" id="64407598"/>
    <dbReference type="GeneID" id="66621738"/>
    <dbReference type="KEGG" id="tfl:RPIT_03350"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00251">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000473">
        <property type="entry name" value="Ribosomal_L36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035977">
        <property type="entry name" value="Ribosomal_L36_sp"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42888">
        <property type="entry name" value="PTHR42888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00444">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57840">
        <property type="entry name" value="SSF57840"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01022">
        <property type="entry name" value="rpmJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00828">
        <property type="entry name" value="RIBOSOMAL_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY30435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="37" mass="4373" checksum="58897B7EBBFEF0D8" modified="2017-04-12" version="1">MKVQPSVKKICDKCKVIRRHGRVMVICDNPRHKQRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDB4</accession>
    <name>A0A1Q2CDB4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03930</name>
        <name evidence="3" type="ORF">SAMN05428934_101390</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY33813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44070">
        <property type="protein sequence ID" value="AQP44070"/>
        <property type="gene ID" value="RPIT_03930"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY33813">
        <property type="protein sequence ID" value="SDY33813"/>
        <property type="gene ID" value="SAMN05428934_101390"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03930"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002560">
        <property type="entry name" value="Transposase_DDE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01610">
        <property type="entry name" value="DDE_Tnp_ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_ISL3" evidence="1">
        <location>
            <begin position="7"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY33813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="124" mass="13752" checksum="C35193FB9A7FD560" modified="2017-04-12" version="1">MFADERHVAFEVTWSVYQDVIDAHQADQPAEGKKIMTRLITSIQSGVPTGLDELQSLGQTMKRRRDDILAFFDHPGTSHGPTEAVNGLLEHLRGTARGFRSIVNYVARCLLDAGGLRPLIHSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDC3</accession>
    <name>A0A1Q2CDC3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_04105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44096">
        <property type="protein sequence ID" value="AQP44096"/>
        <property type="gene ID" value="RPIT_04105"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04105"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="90" mass="9731" checksum="11E2FA0013ACE660" modified="2017-04-12" version="1">MEVLEKLRSSGAVDFEKIGGAVTELAPKLFDPGTVADDYIATGYSSVIHVWKTGMALEELGRPAELQEMADRATKLAEDVQRVAGPGRIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDC6</accession>
    <name>A0A1Q2CDC6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_03855</name>
        <name evidence="2" type="ORF">SAMN05428934_101373</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY33425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03855"/>
    <dbReference type="EnsemblBacteria" id="AQP44055">
        <property type="protein sequence ID" value="AQP44055"/>
        <property type="gene ID" value="RPIT_03855"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY33425">
        <property type="protein sequence ID" value="SDY33425"/>
        <property type="gene ID" value="SAMN05428934_101373"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03855"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY33425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="384" mass="41852" checksum="18A9FE2E514734CD" modified="2017-04-12" version="1">MPSLRIRGATLAGIACAARLAKLGHIVELDTGGDDLGAHWSPAQDRLAPVLTLPATWRDLFKKSGRTLDAELARSSLELIEAPPAIHRFVDGAELPLPTERGRQFAILTARYGQPVAERWRDTLDALDEVWLAARRFGVESPASPTGGANLRALWLDRTLADVAERVGHPHLAEIVLSLAPLAGTRSRRAPGLLASRLVVERTFGRWRLVDADGAALPATRLLGLLEERLATRRVRVVEGLGAEEHSVDCLPRAPLLTRAALAPATSHSWEDRAGEEPFSEVIDHTGRWPVVTWRVPTAEGVSVLTRDYNHAHRAVSWGLEPRSARSVLRRVPIDRAGAPSRASACSPAGPEPWAELASAALAVYEVHERLTGEDCRPTNRSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDG6</accession>
    <name>A0A1Q2CDG6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cysteine desulfurase</fullName>
            <ecNumber evidence="4">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_04360</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04360"/>
    <dbReference type="EnsemblBacteria" id="AQP44141">
        <property type="protein sequence ID" value="AQP44141"/>
        <property type="gene ID" value="RPIT_04360"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04360"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006534">
        <property type="term" value="P:cysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06453">
        <property type="entry name" value="SufS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010970">
        <property type="entry name" value="Cys_dSase_SufS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01979">
        <property type="entry name" value="sufS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_5" evidence="5">
        <location>
            <begin position="33"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="422" mass="45485" checksum="AA121540DA1B11DB" modified="2017-04-12" version="1">MESRVVTTPPLDVEAIRADFPILERRVGEWPLVYLDSANTSQKPRQVVEAIAEHYLQHNANVARAMHLLGAEATEAFEGARSTVASFIGASRTEEVVFTKNASEALNLAAHSLGASLRAGDEVVISVMEHHSNIVPWQMACERSGATLRWFDVTDEGRLDLEGARRDSLINERTRVVALTWVSNVLGTRNPIADVAQQAHAVGATVVVDASQAVPHQPIDVATLGADLVAFTAHKMCGPTGLGVLWGRYELLAELPPFLGGGEMIEVVEMQRSTYAPPPHRFEAGTPPIAQAVGLGAAIDYLSAIGMDAIAHHEQVLTEYALDKLTSIDGLVLLGPTEAVERGSALSFNLQGVHPHDVMQVLDSRGVAIRGGHHCARPLHKRLGHQSSTRASSYLYTTPAEIDALADALVFTRNYFAPRFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDJ1</accession>
    <name>A0A1Q2CDJ1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Choline/glycine/proline betaine transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_04650</name>
        <name evidence="9" type="ORF">SAMN05428934_101537</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BCCT transporter (TC 2.A.15) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04650"/>
    <dbReference type="EnsemblBacteria" id="AQP44192">
        <property type="protein sequence ID" value="AQP44192"/>
        <property type="gene ID" value="RPIT_04650"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37775">
        <property type="protein sequence ID" value="SDY37775"/>
        <property type="gene ID" value="SAMN05428934_101537"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04650"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071705">
        <property type="term" value="P:nitrogen compound transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000060">
        <property type="entry name" value="BCCT_transptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30047">
        <property type="entry name" value="PTHR30047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02028">
        <property type="entry name" value="BCCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY37775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="310" mass="32893" checksum="EA046A6BC97BD488" modified="2017-04-12" version="1">MLITIITALATVSVVTGLDKGIAFPSRANLALAALFLVGVLILGPTLFILRDLIASIGNYVQNFVSLSFQTFPFYGEAGASWLAGWTTNYWAWWISWSPFVGVFIARISRGRTVREFLVGVLLVPTLMTIVWFSVLGGAALHREIFGGGGIIDDGAVDTDTALFDLLATMPGSALLSGIAITLVVIFFVTSADSGAFVVDMLANGGNPTPPVWSRVMWAVLSGSIAAVLIWAGANSSSDMPGANTVGMAALQALTLLAATPFSLVMVAMAFATVKALRADHAQWQAAQDRATRRELVRDTAERVLERPNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDK8</accession>
    <name>A0A1Q2CDK8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide deformylase</fullName>
            <shortName evidence="2">PDF</shortName>
            <ecNumber evidence="2">3.5.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Polypeptide deformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">def</name>
        <name evidence="3" type="ORF">RPIT_04480</name>
        <name evidence="4" type="ORF">SAMN05428934_101502</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe(2+) ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY36953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04480"/>
    <dbReference type="EnsemblBacteria" id="AQP44160">
        <property type="protein sequence ID" value="AQP44160"/>
        <property type="gene ID" value="RPIT_04480"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY36953">
        <property type="protein sequence ID" value="SDY36953"/>
        <property type="gene ID" value="SAMN05428934_101502"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04480"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PTHR10458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="SSF56420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY36953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="202" mass="21815" checksum="E59B06D0601042DF" modified="2017-04-12" version="1">MADADLTRGGTVRPITRWGTPVMHQKTAPVVEFDEELHELIRDMFATMAAADGVGLAATQVGVGLAVFIYECPDADDVIHRGVVCNPVVTVPEGKDRRLEAADEGCLSFPGGYQSLARPDFAVCRGQDENGNDIVVEGTGLLARCLQHETDHLNGTVFGDRLSARSRRQLNTKVSEVAFRYPDDWPVSPKAVATPPAPNSET</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDP7</accession>
    <name>A0A1Q2CDP7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04560</name>
        <name evidence="3" type="ORF">SAMN05428934_101518</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44175">
        <property type="protein sequence ID" value="AQP44175"/>
        <property type="gene ID" value="RPIT_04560"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37345">
        <property type="protein sequence ID" value="SDY37345"/>
        <property type="gene ID" value="SAMN05428934_101518"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04560"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY37345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="137" mass="13874" checksum="368E0C3C0BF61D7F" modified="2017-04-12" version="1">MTIAESRKSWMIGGLTSSLVGLGLMVAPTFPHGDAGHSWWSPTLVTDGAFLALPAALAAVAAAVLGFLKWRSAGQRFVWAPAIWSLVSGVLAAVALVMAGGLTLWAGLAVAAMVVAAGLWTQTARPALPGALPSGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDQ1</accession>
    <name>A0A1Q2CDQ1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04805</name>
        <name evidence="3" type="ORF">SAMN05428934_101569</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY38605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04805"/>
    <dbReference type="EnsemblBacteria" id="AQP44217">
        <property type="protein sequence ID" value="AQP44217"/>
        <property type="gene ID" value="RPIT_04805"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY38605">
        <property type="protein sequence ID" value="SDY38605"/>
        <property type="gene ID" value="SAMN05428934_101569"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04805"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
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        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY38605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="311" mass="32345" checksum="DF0F854D92BD2A10" modified="2017-04-12" version="1">MIWLAIGMQVVSSFLFASGAILQSLGVKSTFDPTGTASSNRLTIAGLLSLFRIPKWLLGLTFVFAGAGIHLVALSFAPVTVVQPVGILAVPWSVLLAARIHKHKLSGKIWRAVAITVTGVVGFTMFSSTFATAVQNVTFAPMFVAFVVVCLVCAVLSYVATKSAPWLKAMMWSSVGATFYGLASGLMKAAMDMILKHDRSFAEPAVLGTIAMMVACYGLGVWMIQQGYASGPAEITVGTMTTVDPFVAVLFGLLVLGEGAGMGVGPALGMAGFGALAVYGVVLLSKDHPDAIEERRVAAEANAPAAAPPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDW0</accession>
    <name>A0A1Q2CDW0_9ACTN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="2" type="ORF">RPIT_05375</name>
        <name evidence="3" type="ORF">SAMN05428934_10322</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY65615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05375"/>
    <dbReference type="EnsemblBacteria" id="AQP44312">
        <property type="protein sequence ID" value="AQP44312"/>
        <property type="gene ID" value="RPIT_05375"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY65615">
        <property type="protein sequence ID" value="SDY65615"/>
        <property type="gene ID" value="SAMN05428934_10322"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05375"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
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    </dbReference>
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        <property type="entry name" value="SSF49503"/>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544440" evidence="1">
        <location>
            <begin position="24"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY65615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="109" mass="11745" checksum="FB89D9403EC075D1" modified="2017-04-12" version="1">MKHVFRLVVILLVGLLAACSAPSAEPQTVELVVTDPPAPTVRVEVPLGAEVTLRITSAIDDRAHLHGYEIEQDLEAGVPTDIVFDATMSGTYELESHVTDAIWADLVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE05</accession>
    <name>A0A1Q2CE05_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH gntR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_05485</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05485"/>
    <dbReference type="EnsemblBacteria" id="AQP44333">
        <property type="protein sequence ID" value="AQP44333"/>
        <property type="gene ID" value="RPIT_05485"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05485"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="234" mass="25068" checksum="88B5D3B371F3A98A" modified="2017-04-12" version="1">MGSGGFDAVLDHLTTEILEGRIGPGSRLPNERELAAHLEVSRSAVREAIKVFQAQGVITSHTGPGRGTRVTGSQGDALGRILKLHVALDVISFDEVTETRVVLERAAAMGAAEHRRDEGLAQLRALAEEMVSATEISDFNALDTRFHVAIASLAANRLIRDLTIAIREAVALHILAAEREMDGWPELRTRLVAEHDGIVEALTLGDGALAADRCEAHIRGAHRAFLETPSARGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE34</accession>
    <name>A0A1Q2CE34_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HIT family hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_05695</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05695"/>
    <dbReference type="EnsemblBacteria" id="AQP44366">
        <property type="protein sequence ID" value="AQP44366"/>
        <property type="gene ID" value="RPIT_05695"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05695"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01275">
        <property type="entry name" value="FHIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039383">
        <property type="entry name" value="FHIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="4">
        <location>
            <begin position="43"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="3">
        <location>
            <begin position="136"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-AMP-histidine intermediate" evidence="2">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR639383-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="178" mass="19745" checksum="1C324D748CD5AB24" modified="2017-04-12" version="1">MSDVEQSDSLPGVPDAFQRLWTPHRMVYIRGEGKPASTGECPFCVSPQRSDEDGLVVARGEHAYVVMNLFPYSPGHLLVCPYRHVRDYTDLTTDETREVAELTQQAMRVLRRVSNPHGFNLGMNQGEVAGAGIAAHLHQHVVPRWAGDMNFMPVVGRTRALPQLLGDARSQLAEAWGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE37</accession>
    <name>A0A1Q2CE37_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_05390</name>
        <name evidence="2" type="ORF">SAMN05428934_10325</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44315">
        <property type="protein sequence ID" value="AQP44315"/>
        <property type="gene ID" value="RPIT_05390"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY65707">
        <property type="protein sequence ID" value="SDY65707"/>
        <property type="gene ID" value="SAMN05428934_10325"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05390"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY65707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="70" mass="7483" checksum="245C1121B92A848C" modified="2017-04-12" version="1">MEPTTISFHEEDDAEATITALAGAGFYVEADRERFLGEDDDEEVVYLVLTDAAADEARGLVVGDGFVISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE47</accession>
    <name>A0A1Q2CE47_9ACTN</name>
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        <submittedName>
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        <name evidence="8" type="ORF">SAMN05428934_10336</name>
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY66036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44325">
        <property type="protein sequence ID" value="AQP44325"/>
        <property type="gene ID" value="RPIT_05445"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY66036">
        <property type="protein sequence ID" value="SDY66036"/>
        <property type="gene ID" value="SAMN05428934_10336"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05445"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
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        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
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    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF88946"/>
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    </dbReference>
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        <location>
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            <end position="85"/>
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        <location>
            <begin position="107"/>
            <end position="157"/>
        </location>
    </feature>
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            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
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            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
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            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY66036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="179" mass="20479" checksum="859995479F712E98" modified="2017-04-12" version="1">MTGLTEATRTWDSFDEFVHARSVALWRSAWLLTGDTQRAEDLVQEALGRCWGKFDRLNRAGNSFEAYVRTAIYHAYLSWWRAGTWREGTMPAGNPEPARHDSVADRDLLRALAALPRQQRAVVVLRYFEDRSTAEAADLLRISQGAVKTHLHRALSSLRSSHHLRTQDLSYLPKEDDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE58</accession>
    <name>A0A1Q2CE58_9ACTN</name>
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        <submittedName>
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        </submittedName>
        <submittedName>
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        </submittedName>
    </protein>
    <gene>
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    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriaceae</taxon>
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    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05775"/>
    <dbReference type="EnsemblBacteria" id="AQP44381">
        <property type="protein sequence ID" value="AQP44381"/>
        <property type="gene ID" value="RPIT_05775"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67747">
        <property type="protein sequence ID" value="SDY67747"/>
        <property type="gene ID" value="SAMN05428934_103102"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05775"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
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        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="YRDC"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="14"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY67747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="207" mass="22659" checksum="4AE89C0A5483B973" modified="2017-04-12" version="1">MAQYFDVHPENPQPRTMAQAARLLEEGGLIAYPTDSCFALGCLLGNTEGLNRIRRIRHLDDKHHFTLVVDSFAKLGAYVEMDNWVFRAVKAATPGPYTFILKASREVPKAMQHPKKRTIGVRIPDHRTTLALLDAVGSPLLSSTLILPDHDDQLTDGWTIKEALDHQIDAVIDSGDAGSVPTTVVDLTGDEPEIVRLGAGDPGPFEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE73</accession>
    <name>A0A1Q2CE73_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44424">
        <property type="protein sequence ID" value="AQP44424"/>
        <property type="gene ID" value="RPIT_06025"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06025"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="103" mass="11446" checksum="EA62765DB56AF165" modified="2017-04-12" version="1">MKRTGSTYTLERGWAFNNLTYLPFMKQSQWANNPLGRPGTFVGGDGAQWRTECNTAATGGNGCRAYRLTTVYFAKPTSSGGYTFGQQNQWALNHIVMFGGYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEB7</accession>
    <name>A0A1Q2CEB7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1648 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44395">
        <property type="protein sequence ID" value="AQP44395"/>
        <property type="gene ID" value="RPIT_05850"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05850"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012867">
        <property type="entry name" value="DUF1648"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07853">
        <property type="entry name" value="DUF1648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1648" evidence="2">
        <location>
            <begin position="24"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="185" mass="20583" checksum="33D8335643C0FC1C" modified="2017-04-12" version="1">MAAEAKLLQREPAGGWRRLVLAAAVVGWLLSLVWLNLTLPERVPTHWSGGGVPDGWSSRTSAVGFALLLPLATVAPMLWISRLVLVWPDGINAPHKEWWLGRPRRLIRFERLLREDLMVIVALTLGLFVAISLIIGYAAHEPGGVVPAWWFPVLVVAYLAVLTAVTVRIYTGSRYRPDDHDRELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEC3</accession>
    <name>A0A1Q2CEC3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Shikimate kinase</fullName>
            <shortName evidence="2">SK</shortName>
            <ecNumber evidence="2">2.7.1.71</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">aroK</name>
        <name evidence="3" type="ORF">RPIT_06210</name>
        <name evidence="4" type="ORF">SAMN05428934_103187</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + shikimate = 3-phosphoshikimate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13121"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.71"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the shikimate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.71" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY69909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06210"/>
    <dbReference type="EnsemblBacteria" id="AQP44456">
        <property type="protein sequence ID" value="AQP44456"/>
        <property type="gene ID" value="RPIT_06210"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY69909">
        <property type="protein sequence ID" value="SDY69909"/>
        <property type="gene ID" value="SAMN05428934_103187"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06210"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00088"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004765">
        <property type="term" value="F:shikimate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00464">
        <property type="entry name" value="SK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00109">
        <property type="entry name" value="Shikimate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000623">
        <property type="entry name" value="Shikimate_kinase/TSH1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 2" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY69909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="165" mass="17897" checksum="6CCF661147637AF8" modified="2017-04-12" version="1">MTIVLMGAPGAGKTSTGKRLARRLGKTFVDVDQRIEEVMGKPVAEIFADEGEAHFRELEEEATLELLESHDVVALGGGAVMNPSIQEALRGHDVIWLKVSIGQATRRVGMNKARPLLLGNVRGKLIELLRERTPVYERLATQVIDTDGRGSVEVADQLAAERGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEC5</accession>
    <name>A0A1Q2CEC5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05900"/>
    <dbReference type="EnsemblBacteria" id="AQP44405">
        <property type="protein sequence ID" value="AQP44405"/>
        <property type="gene ID" value="RPIT_05900"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05900"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046283">
        <property type="entry name" value="DUF6320"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19845">
        <property type="entry name" value="DUF6320"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="200" mass="21861" checksum="B370232E1ED5DA11" modified="2017-04-12" version="1">MELDHVEARLASREIFPAPPLRFDRRQVWAAVVALSVLVLIFSFAAPALVPGLVAPVRTVWLSVAVVWLVVIAAVQRRRNVGSLVGWLVLLLSVAAVVWNQYDGPDFWATTWVVPAICTAANLALGVIVWIVRLDPQEHLAKALLVGLIGLVPGLFVLFGWVATPLPALICVGFSLLVVSLILIIRPRQLGSALRRRLHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEK0</accession>
    <name>A0A1Q2CEK0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Homoserine kinase</fullName>
            <shortName evidence="10">HK</shortName>
            <shortName evidence="10">HSK</shortName>
            <ecNumber evidence="4 10">2.7.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">thrB</name>
        <name evidence="12" type="ORF">RPIT_06740</name>
        <name evidence="13" type="ORF">SAMN05428934_11099</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + L-homoserine = ADP + H(+) + O-phospho-L-homoserine</text>
            <dbReference type="Rhea" id="RHEA:13985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.39"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the GHMP kinase family. Homoserine kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.39" evidence="4 10"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ10001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06740"/>
    <dbReference type="EnsemblBacteria" id="AQP44549">
        <property type="protein sequence ID" value="AQP44549"/>
        <property type="gene ID" value="RPIT_06740"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ10001">
        <property type="protein sequence ID" value="SDZ10001"/>
        <property type="gene ID" value="SAMN05428934_11099"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06740"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00064"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004413">
        <property type="term" value="F:homoserine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00384">
        <property type="entry name" value="Homoser_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000870">
        <property type="entry name" value="Homoserine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000676">
        <property type="entry name" value="Homoser_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00191">
        <property type="entry name" value="thrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0791">Threonine biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="11">
        <location>
            <begin position="81"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP44549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDZ10001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="296" mass="30881" checksum="2E03F1D27DF7BB72" modified="2017-04-12" version="1">MRRLTVRVPATTANLGSGFDCVGMAFDWFDDLTLDVLEAPGIEVVVTGEGAGDVPLDERHLVVSSILDGLRAFGVAPPGMRLTCHNAIPHSRGLGSSAAAIVAGLTLAHGIARPGEPLDRAVITRLADEAEGHPDNVGAAVWGGAILAWSREGRVSLVQLPLPDGFAAVAFVPETECRTDEARSVLPDHVRRTDAVAQAIAAAALPLALTQRPDLLFDATRDLLHQTFRAPLMQPSYDLMLRLREAGVAAAISGAGPTVIAVGLPEQLAPVEGVGTAGFAVRRLLPAGGVELSESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEL2</accession>
    <name>A0A1Q2CEL2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_06710</name>
        <name evidence="8" type="ORF">SAMN05428934_110105</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ10118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06710"/>
    <dbReference type="EnsemblBacteria" id="AQP44543">
        <property type="protein sequence ID" value="AQP44543"/>
        <property type="gene ID" value="RPIT_06710"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ10118">
        <property type="protein sequence ID" value="SDZ10118"/>
        <property type="gene ID" value="SAMN05428934_110105"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06710"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ10118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="379" mass="40035" checksum="AAA30881512BDB64" modified="2017-04-12" version="1">MREYLLVFLVAAGVTYLLAGIFRSLAVRTGALAPVRNRDVHTHPIPYFGGIAMFGGLAVAFLLALQMPFLGRYTAVEHDAYAVLWAGLVICVVGVLDDKYDLPALVKLGGQVLAAGVAVLQGVRIYWIPLPDRIVALDDSLSILVTVLFIAICVNAVNFVDGLDGLAGGIVAIGSGAFFSYTYVLAYEQELARATTASLITVATCGIAVGFLGHNLHPAKMFMGDSGAMLLGLLMAMSAVSFTGQLDPSAIAAGGAFLPAILPILLPVAALALPFLDLVLAWARRVWAGQHPFAADKLHLHHRLLARGHSHWGAVLLMYGWTAVVSVGLVVIALVQGYSAWWIGAMLVILLALTIRPVRSAPPELGGASSDVVDPVRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEL8</accession>
    <name>A0A1Q2CEL8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)</fullName>
            <ecNumber evidence="4">5.4.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">RPIT_06595</name>
        <name evidence="14" type="ORF">SAMN05428934_103264</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23536"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="5.4.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.2" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06595"/>
    <dbReference type="EnsemblBacteria" id="AQP44520">
        <property type="protein sequence ID" value="AQP44520"/>
        <property type="gene ID" value="RPIT_06595"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71992">
        <property type="protein sequence ID" value="SDY71992"/>
        <property type="gene ID" value="SAMN05428934_103264"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06595"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004614">
        <property type="term" value="F:phosphoglucomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045244">
        <property type="entry name" value="PGM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005852">
        <property type="entry name" value="PGM_a-D-Glc-sp"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22573">
        <property type="entry name" value="PTHR22573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01132">
        <property type="entry name" value="pgm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="10">
        <location>
            <begin position="40"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="11">
        <location>
            <begin position="206"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="12">
        <location>
            <begin position="316"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="9">
        <location>
            <begin position="464"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP44520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY71992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="541" mass="57396" checksum="6F0BC795797ED791" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CES3</accession>
    <name>A0A1Q2CES3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aldo/keto reductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Voltage-dependent potassium channel beta subunit, animal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_06880</name>
        <name evidence="5" type="ORF">SAMN05428934_11070</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shaker potassium channel beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06880"/>
    <dbReference type="EnsemblBacteria" id="AQP44570">
        <property type="protein sequence ID" value="AQP44570"/>
        <property type="gene ID" value="RPIT_06880"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09522">
        <property type="protein sequence ID" value="SDZ09522"/>
        <property type="gene ID" value="SAMN05428934_11070"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06880"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005399">
        <property type="entry name" value="K_chnl_volt-dep_bsu_KCNAB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150">
        <property type="entry name" value="PTHR43150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01577">
        <property type="entry name" value="KCNABCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="3">
        <location>
            <begin position="15"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ09522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="334" mass="36838" checksum="40B1EAB2E0ABCCB7" modified="2017-04-12" version="1">MKYRYLGDSGLKITELTYGNWLTHGSQVEADQATACVRAALDAGITSFDTADVYANTVAEEVLGEALKGERRESLEIFTKVYWPVGPKGANDVGLSRKHIMEGINGSLKRLKTDYVDLYQAHRFDVETPLEETMVALADVVRQGKALYIGVSEWPADKIREGAALAKELRIPFISNQPQYSMLWRVIEDEVVPASREVGVSQIVWSPVAQGILTGKYKPGQPAPEGSRATDKKGGQQMIERWLRDDVLERVQNLRPVADELGITMAQLAVAWVLHNDNVAAAIIGASRPEQITENVKASEVELSDDVMARIDDILGDVVERDAAKINVPEKRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CES7</accession>
    <name>A0A1Q2CES7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transcriptional regulator WhiB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">whiB</name>
        <name evidence="13" type="ORF">RPIT_06785</name>
        <name evidence="14" type="ORF">SAMN05428934_11089</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">The Fe-S cluster can be nitrosylated by nitric oxide (NO).</text>
    </comment>
    <comment type="PTM">
        <text evidence="11">Upon Fe-S cluster removal intramolecular disulfide bonds are formed.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the WhiB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06785"/>
    <dbReference type="EnsemblBacteria" id="AQP44555">
        <property type="protein sequence ID" value="AQP44555"/>
        <property type="gene ID" value="RPIT_06785"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09849">
        <property type="protein sequence ID" value="SDZ09849"/>
        <property type="gene ID" value="SAMN05428934_11089"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06785"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035731">
        <property type="term" value="F:dinitrosyl-iron complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01479">
        <property type="entry name" value="WhiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034768">
        <property type="entry name" value="4FE4S_WBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003482">
        <property type="entry name" value="Whib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38839">
        <property type="entry name" value="PTHR38839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02467">
        <property type="entry name" value="Whib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51674">
        <property type="entry name" value="4FE4S_WBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 11" id="KW-0408">Iron</keyword>
    <keyword evidence="6 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 11" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="4Fe-4S Wbl-type" evidence="12">
        <location>
            <begin position="8"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP44555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDZ09849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="83" mass="9462" checksum="78C670E8A1BA0758" modified="2017-04-12" version="1">MDWRHKAACLTEDPELFFPVGNTGPALQQIEEAKKICQRCVVREQCLAWALEAGQDHGVWGGLSEDERRAIKRRAARSRLRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEZ6</accession>
    <name>A0A1Q2CEZ6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44689">
        <property type="protein sequence ID" value="AQP44689"/>
        <property type="gene ID" value="RPIT_07610"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07610"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="62" mass="6529" checksum="482929698AABC49B" modified="2017-04-12" version="1">MKLDDECPSSVRRPYSEVQGLPSTVNSHGSVAPPLAETTTDGALKVIFTSTPPSSRGTLTLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF08</accession>
    <name>A0A1Q2CF08_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_07700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07700"/>
    <dbReference type="EnsemblBacteria" id="AQP44704">
        <property type="protein sequence ID" value="AQP44704"/>
        <property type="gene ID" value="RPIT_07700"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07700"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007318">
        <property type="entry name" value="Phopholipid_MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04191">
        <property type="entry name" value="PEMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="212" mass="22102" checksum="2CC355B1081CD1A6" modified="2017-04-12" version="1">MGGIDEWGPRVSAGVALAVYVIGLAGAFGVRAWLHRRRTGDSGVRRTPARHPAGRMGVVLFIGALLLCGAGLVGALLAPQLRWEAPGVVSWAGLLVAAVGLAAVFVAQAAMGASWRVGVDPDEVTELVTTGPFALVRNPIFSAMGLTLVGVTLLVPSAATVLALVAFCVGVQLQVRLVEEPALARLHGDRYRQYASTVGRFLPDLTRGRSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF15</accession>
    <name>A0A1Q2CF15_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07730</name>
        <name evidence="3" type="ORF">SAMN05428934_11810</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000018">
        <property type="protein sequence ID" value="SDZ21404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07730"/>
    <dbReference type="EnsemblBacteria" id="AQP44709">
        <property type="protein sequence ID" value="AQP44709"/>
        <property type="gene ID" value="RPIT_07730"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ21404">
        <property type="protein sequence ID" value="SDZ21404"/>
        <property type="gene ID" value="SAMN05428934_11810"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07730"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13443">
        <property type="entry name" value="HTH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="13"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ21404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="72" mass="7786" checksum="A0C6A8E33086F6DB" modified="2017-04-12" version="1">MAVEEAHRVVCRLDELLEARGMTLTALADEVGVTVVNLSILKNQRAKAIRFSTLTALCDVLGCQPGDLFAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF41</accession>
    <name>A0A1Q2CF41_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease VapC</fullName>
            <shortName evidence="6">RNase VapC</shortName>
            <ecNumber evidence="6">3.1.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Toxin VapC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">vapC</name>
        <name evidence="8" type="ORF">RPIT_07815</name>
        <name evidence="9" type="ORF">SAMN05428934_1133</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Toxic component of a toxin-antitoxin (TA) system. An RNase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PINc/VapC protein family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07815"/>
    <dbReference type="EnsemblBacteria" id="AQP44723">
        <property type="protein sequence ID" value="AQP44723"/>
        <property type="gene ID" value="RPIT_07815"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16041">
        <property type="protein sequence ID" value="SDZ16041"/>
        <property type="gene ID" value="SAMN05428934_1133"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07815"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00265">
        <property type="entry name" value="VapC_Nob1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022907">
        <property type="entry name" value="VapC_family"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0800">Toxin</keyword>
    <keyword evidence="1 6" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="domain" description="PINc" evidence="7">
        <location>
            <begin position="2"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="5"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ16041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="142" mass="15225" checksum="61326A06AD64B656" modified="2017-04-12" version="1">MIIADTDVVSEFMKDTPEASVMAWARDLAASDLTISVVTVEEIVRGLGRLPAGRRRKDLEARWNTLVSAFADAIAVYDVTAARATARLLVDGLTQGRTMSLADAQIAGICLANGATLATRNVKDFPHVSDLTVVNPFDADHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFC1</accession>
    <name>A0A1Q2CFC1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_08325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08325"/>
    <dbReference type="EnsemblBacteria" id="AQP44803">
        <property type="protein sequence ID" value="AQP44803"/>
        <property type="gene ID" value="RPIT_08325"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08325"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="216" mass="22791" checksum="E3AB1C63EC6909F0" modified="2017-04-12" version="1">MTKVVLIRHGRSTANAAGVLAGRAAVALDEFGRAQAEALREALSGVQVAAAYTSPIERCRETAALAGFPDAEVADGLSECDYGDWTGLKLDELMKEQVWTDIQARPTEVSFPGGETMTGMFDRVSAAIDELTGRHADDETIVAFSHGDPIKGILAHAFGMRRDDFQRIHVAPAGISAIDYRQPHPMVLCVNVGGALAAHLGVARGPVVGGGDVGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFF5</accession>
    <name>A0A1Q2CFF5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-binding protein KhpA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">KH-domain protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">khpA</name>
        <name evidence="2" type="ORF">RPIT_08595</name>
        <name evidence="3" type="ORF">SAMN05428934_10730</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">A probable RNA-binding protein.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the KhpA RNA-binding protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY96828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08595"/>
    <dbReference type="EnsemblBacteria" id="AQP44841">
        <property type="protein sequence ID" value="AQP44841"/>
        <property type="gene ID" value="RPIT_08595"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY96828">
        <property type="protein sequence ID" value="SDY96828"/>
        <property type="gene ID" value="SAMN05428934_10730"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08595"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00088">
        <property type="entry name" value="UPF0109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020627">
        <property type="entry name" value="KhpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34654">
        <property type="entry name" value="PTHR34654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY96828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="82" mass="9024" checksum="9E03612F83F0E788" modified="2017-04-12" version="1">MLAEALEHLVAGIVSNPDDVSVKDKDLRRGRLLEVRVHPDDVGKVIGRQGRTASALRTVVAALAGKESVRVDFVDVDRPRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFF6</accession>
    <name>A0A1Q2CFF6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-2 type transport system ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Export ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_08650</name>
        <name evidence="6" type="ORF">SAMN05428934_10740</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44849">
        <property type="protein sequence ID" value="AQP44849"/>
        <property type="gene ID" value="RPIT_08650"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97051">
        <property type="protein sequence ID" value="SDY97051"/>
        <property type="gene ID" value="SAMN05428934_10740"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08650"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY97051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="305" mass="33207" checksum="E34F5163573EFFF7" modified="2017-04-12" version="1">MIETRNLTKRYGSKTVVDNLSVQIQPGVVTGFLGPNGAGKSTTMRMLLGLERPTSGTALIDGVPYRTLKRPLTTVGALLDAGWVHPKRSARDHLRWVAASNRIDTARVDEILEIVGLREAARRKAGEFSLGMRQRLGLATAMLGDPQHYILDEPVNGLDPEGIHWIRQVMRRLADQGKTVLVSSHLLSEMSQTADNLIVIAQGRLLADTTVEAFVAAQGAGKIRVRARRLDELAAALRHRGAEVIVRDSAQDRCLAVTGLSIEEVADVAGDYGVLELGQERVSLEDAFIEMTRDGVEYAGSVGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFK2</accession>
    <name>A0A1Q2CFK2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Predicted acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08920</name>
        <name evidence="3" type="ORF">SAMN05428934_10797</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08920"/>
    <dbReference type="EnsemblBacteria" id="AQP44896">
        <property type="protein sequence ID" value="AQP44896"/>
        <property type="gene ID" value="RPIT_08920"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98204">
        <property type="protein sequence ID" value="SDY98204"/>
        <property type="gene ID" value="SAMN05428934_10797"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08920"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025559">
        <property type="entry name" value="Eis_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13530">
        <property type="entry name" value="SCP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SSF55718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY98204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="409" mass="45632" checksum="DA588FD7907B26F8" modified="2017-04-12" version="1">MHEMRTIPVTDELTAELRAYAVAMRDGFHEAPITADGWARWHEAIRHDGARLRGVFDPDRPFGLASVPVGTFASFPGTINTGTELAPTNCITDVTVAASHRRRGIMQQMMTTDLNEARERGDVFAALTATDTRLYGRFGFGVTADSRRIEINTGHSFGLISQPSGSCVFATGDDASAVRRSLFERWHAEQFWSITRHHHYWQPGFDWATQTARHDRHIIHLDDDGHADAAAVIVVRDDHVEIRDLLGLSHRAELEIIRFVALLETHDKVVWRHCFDVRHPLPWAVTDRRSVSVVKEFDTLWVRIVDVERALASRSYEGDGEATIRVVDPLDDNTFTYRIRVAGGQPDVETTSREPDATLPLDSLAPIYSALQGPKELASAGRAQGTPEGLARVARLFAREEPGISASIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFP3</accession>
    <name>A0A1Q2CFP3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TauD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_09105</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09105"/>
    <dbReference type="EnsemblBacteria" id="AQP44928">
        <property type="protein sequence ID" value="AQP44928"/>
        <property type="gene ID" value="RPIT_09105"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09105"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD" evidence="3">
        <location>
            <begin position="11"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="211" mass="23226" checksum="6DCD86FF1A6D5891" modified="2017-04-12" version="1">MLEPGPAVASDPAAVIELARRYGTVSERDGGGAWPIQSQVPSGTFSVTNDAAPLHTDAQYRNDPEDAFLLACARSAAQGGDSILLAVDDLVATLSRRSDWFSLQGLLQAPIWRWRTPEVFDGPRESEPAAILYPREDGRYSMRWRMDNLVADQSAAWAAEVVHQTAAIDPNLAVLKLRPGQVLVCDNSTVLHGRTAFNDPTRLLWRVRVHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFT2</accession>
    <name>A0A1Q2CFT2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09045</name>
        <name evidence="3" type="ORF">SAMN05428934_107122</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44920">
        <property type="protein sequence ID" value="AQP44920"/>
        <property type="gene ID" value="RPIT_09045"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98686">
        <property type="protein sequence ID" value="SDY98686"/>
        <property type="gene ID" value="SAMN05428934_107122"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09045"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY98686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="210" mass="22491" checksum="F88500E13C868A48" modified="2017-04-12" version="1">MPSTRIRPLRRAADVISDAVLVLWCLLWAGVAWALKSVVDALAVPAEGIGRTAGDLAGRVDDAADRLGDVALVGDELARPFSPIADGLRQLSAQSVEQAEAVYQAGWLLFLVVFLIPSLTLALLYLPRRVRRAKESAAARRYIDSAADLDLFALRALANSPMTQLAEISPDPVADWRSGDRAVITALANLELRRVGIGTLNLDQPTGSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFX1</accession>
    <name>A0A1Q2CFX1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">4-alpha-glucanotransferase</fullName>
            <ecNumber evidence="3 7">2.4.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 7">Amylomaltase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6 7">Disproportionating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_09535</name>
        <name evidence="9" type="ORF">SAMN05428934_102399</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1-&gt;4)-alpha-D-glucan.</text>
            <dbReference type="EC" id="2.4.1.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the disproportionating enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.25" evidence="3 7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY59728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09535"/>
    <dbReference type="EnsemblBacteria" id="AQP44997">
        <property type="protein sequence ID" value="AQP44997"/>
        <property type="gene ID" value="RPIT_09535"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59728">
        <property type="protein sequence ID" value="SDY59728"/>
        <property type="gene ID" value="SAMN05428934_102399"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09535"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004134">
        <property type="term" value="F:4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102500">
        <property type="term" value="F:beta-maltose 4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003385">
        <property type="entry name" value="Glyco_hydro_77"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32438">
        <property type="entry name" value="PTHR32438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02446">
        <property type="entry name" value="Glyco_hydro_77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00217">
        <property type="entry name" value="malQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020295"/>
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    <evidence type="ECO:0000256" key="5">
        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361207"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP44997.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY59728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="716" mass="80557" checksum="467374273E5E936D" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
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        <name evidence="7" type="ORF">SAMN05428934_102370</name>
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
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    </organism>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        </source>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
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        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="gene ID" value="SAMN05428934_102370"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="MscS_channel"/>
    </dbReference>
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        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="36"/>
        </location>
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            <end position="74"/>
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            <end position="160"/>
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        <location>
            <begin position="416"/>
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        </location>
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        </location>
    </feature>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
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</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG00</accession>
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        </submittedName>
    </protein>
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    </gene>
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        </location>
    </feature>
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            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="59" mass="6471" checksum="7B60798C686DA5B1" modified="2017-04-12" version="1">MTPLPPPPRPPPPEPRPPRPAPRPPPPRPTLPLRTTPRAWSPTQVASTTSRSTRRPTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG19</accession>
    <name>A0A1Q2CG19_9ACTN</name>
    <protein>
        <submittedName>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">RP1T</strain>
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            <end position="206"/>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="590" mass="61857" checksum="E824CFBD7E85ACA3" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG26</accession>
    <name>A0A1Q2CG26_9ACTN</name>
    <protein>
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        <submittedName>
            <fullName evidence="3">Inosine 5-monophosphate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09950</name>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">RP1T</strain>
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    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IMPDH/GMPR family.</text>
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        <property type="protein sequence ID" value="AQP45072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY57328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09950"/>
    <dbReference type="EnsemblBacteria" id="AQP45072">
        <property type="protein sequence ID" value="AQP45072"/>
        <property type="gene ID" value="RPIT_09950"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57328">
        <property type="protein sequence ID" value="SDY57328"/>
        <property type="gene ID" value="SAMN05428934_102316"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09950"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005990">
        <property type="entry name" value="IMP_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005992">
        <property type="entry name" value="IMP_DH-rel2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911">
        <property type="entry name" value="PTHR11911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911:SF85">
        <property type="entry name" value="PTHR11911:SF85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01304">
        <property type="entry name" value="IMP_DH_rel_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IMPDH" evidence="2">
        <location>
            <begin position="13"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY57328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="366" mass="39435" checksum="85F931ED050A0DEB" modified="2017-04-12" version="1">MYELGRSKRASHAYSFDDVAIAPTRRTRSDDEVDLTWKIDAVSFEVPIVAAPMDSVMSPATAIRMGELGGLGVLNLEGLWTRYEDPQPQYELLTQQCDQVTATRRMQEIYAEPVKPELIRDRLAEIRNAGVPVAGSLSPARTLEFAPVLEQAGMDFFVIRGTTVSAEHVGGEETLNLKDFIYRFDVPVLVGGVATYRAALHLMRSGAAGVLVGFGGGATHTTASVLGIEVPMASAVADVAEARRDYLEESGGRYVHILADGAVGRSGDIAKAIASGADAVMVGSPLARATEAPGRGWHWGSEAWHPRLPRGERSFFDQVGTLEEVVLGPSRVPDGTMNLAGGLRKAMALTGYTDIKSFQRIDLILH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG42</accession>
    <name>A0A1Q2CG42_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">tRNA (Adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">tRNA threonylcarbamoyl adenosine modification protein YeaZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_10045</name>
        <name evidence="4" type="ORF">SAMN05428934_102297</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10045"/>
    <dbReference type="EnsemblBacteria" id="AQP45088">
        <property type="protein sequence ID" value="AQP45088"/>
        <property type="gene ID" value="RPIT_10045"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56864">
        <property type="protein sequence ID" value="SDY56864"/>
        <property type="gene ID" value="SAMN05428934_102297"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10045"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022496">
        <property type="entry name" value="T6A_TsaB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF11">
        <property type="entry name" value="PTHR11735:SF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03725">
        <property type="entry name" value="T6A_YeaZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TsaD" evidence="2">
        <location>
            <begin position="33"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY56864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="215" mass="22775" checksum="0AF22E877EF04BD8" modified="2017-04-12" version="1">MTWTLAIDTSHFVAVGLAGDGVAAASVVVDDTRAHAEALMPSVLAACAEAGIALREVDEFAVGMGPGPFTGLRVGVATAWTLAHLAGTEPHGVCSLDVVARQWSDEGAPDEFVVAADARRKELYWARYRSDGSRVGEPQVSAPDQLPDLPVAGEIPELYRHLLRTDGPSTLDPAVLATSWRRMAPAGDEPYYLRAPDATVPGKPKSALPRLRAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG47</accession>
    <name>A0A1Q2CG47_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA N6-adenosine threonylcarbamoyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.234</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">N6-L-threonylcarbamoyladenine synthase</fullName>
            <shortName evidence="6">t(6)A synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tsaD</name>
        <name evidence="8" type="ORF">RPIT_10035</name>
        <name evidence="9" type="ORF">SAMN05428934_102299</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>adenosine(37) in tRNA + L-threonylcarbamoyladenylate = AMP + H(+) + N(6)-L-threonylcarbamoyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="6">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10035"/>
    <dbReference type="EnsemblBacteria" id="AQP45086">
        <property type="protein sequence ID" value="AQP45086"/>
        <property type="gene ID" value="RPIT_10035"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56912">
        <property type="protein sequence ID" value="SDY56912"/>
        <property type="gene ID" value="SAMN05428934_102299"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10035"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01445">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017860">
        <property type="entry name" value="Peptidase_M22_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022450">
        <property type="entry name" value="TsaD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF6">
        <property type="entry name" value="PTHR11735:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03723">
        <property type="entry name" value="T6A_TsaD_YgjD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01016">
        <property type="entry name" value="GLYCOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TsaD" evidence="7">
        <location>
            <begin position="32"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="142"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY56912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="353" mass="36288" checksum="F6510AA2F5F2C0D1" modified="2017-04-12" version="1">MTEALSPSGPLVLGLESSCDETGVGIVRGHTLLANEVASSVDLHVRFGGVVPEVASRAHLSALIPTLERAADTAGIDLADLDGIAVTAGPGLMGALVVGVASAKALAAYLGKPLYGVNHLVGHVAVDLLDHGPLPTPSLALLVSGGHTQLLHVEDIATKITEVGTTIDDAAGEAYDKVARILGLSYPGGPVIDRAAQEGDPTAIRFPRGLTARHDLEKHRFDFSFSGLKTAVARWVEQRRLDGLDVPVPDVAASFQEAVCDVLTAKTIDAAQHYGVDTILLGGGVAANSRLRTLLEQRATDAGIAVRRPRPALCTDNGAMIAAVGAEVIRAGLPPSGMGISAHSGLPVSTVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG53</accession>
    <name>A0A1Q2CG53_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-oxoadipate enol-lactonase/3-oxoadipate enol-lactonase / 4-carboxymuconolactone decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10105</name>
        <name evidence="3" type="ORF">SAMN05428934_102284</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45098">
        <property type="protein sequence ID" value="AQP45098"/>
        <property type="gene ID" value="RPIT_10105"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56524">
        <property type="protein sequence ID" value="SDY56524"/>
        <property type="gene ID" value="SAMN05428934_102284"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10105"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="44"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY56524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="273" mass="29937" checksum="321572DD5A030567" modified="2017-04-12" version="1">MELNWTVYNPETPAERVLIVGPSLGGNATHQWTPVAAQLIHEARVIFVDLPGTGLAPVWDDEVEPSLDELAAGIAQVADKIRAEEGDVPIWFAGLSISGAVALHVARDYPEKFAGVVMVASAAKVGEPDRWRERADMVEEKGTQVLVDETVKRWFTPTFRAQRPAVVDAIMEGLSVADDHSYAQLCRALAEHDMREELSLIRIPVIAIAGERDSSTPLENVEYVAETVLRGGLHIIDGAAHQVPVSHPTEVATIIRPLLHRRRESRVVSESED</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGA7</accession>
    <name>A0A1Q2CGA7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10360</name>
        <name evidence="2" type="ORF">SAMN05428934_102233</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10360"/>
    <dbReference type="EnsemblBacteria" id="AQP45146">
        <property type="protein sequence ID" value="AQP45146"/>
        <property type="gene ID" value="RPIT_10360"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55129">
        <property type="protein sequence ID" value="SDY55129"/>
        <property type="gene ID" value="SAMN05428934_102233"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10360"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037079">
        <property type="entry name" value="AF2212/PG0164-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015018">
        <property type="entry name" value="DUF1905"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08922">
        <property type="entry name" value="DUF1905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY55129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="202" mass="21589" checksum="46206AA3C658C5EC" modified="2017-04-12" version="1">MPHVSVTTTVEEFGPAAAIFLTDEQAAQLSTAKTPPVVVSIGGRQERLRISRMGGRACIGLSRASRDALGVEIGDEVDVTVSLDDEERTVEVPPLLAEALAADPDASEAFRELSLDPPIPRCYATPCRHTGIADHAQGTPGSSSRASSCRCTHLVPLAARPIGGSRLSYSRRKEMARSFDEAKREDTQQRRLAAVLADLAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGF9</accession>
    <name>A0A1Q2CGF9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidyl-tRNA hydrolase</fullName>
            <shortName evidence="1">PTH</shortName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pth</name>
        <name evidence="2" type="ORF">RPIT_10725</name>
        <name evidence="3" type="ORF">SAMN05428934_102160</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PTH family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY52900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10725"/>
    <dbReference type="EnsemblBacteria" id="AQP45209">
        <property type="protein sequence ID" value="AQP45209"/>
        <property type="gene ID" value="RPIT_10725"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY52900">
        <property type="protein sequence ID" value="SDY52900"/>
        <property type="gene ID" value="SAMN05428934_102160"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10725"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:aminoacyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00462">
        <property type="entry name" value="PTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00083">
        <property type="entry name" value="Pept_tRNA_hydro_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001328">
        <property type="entry name" value="Pept_tRNA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018171">
        <property type="entry name" value="Pept_tRNA_hydro_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036416">
        <property type="entry name" value="Pept_tRNA_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224">
        <property type="entry name" value="PTHR17224"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01195">
        <property type="entry name" value="Pept_tRNA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53178">
        <property type="entry name" value="SSF53178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00447">
        <property type="entry name" value="pth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01196">
        <property type="entry name" value="PEPT_TRNA_HYDROL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY52900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="194" mass="20633" checksum="3E233EF90817723C" modified="2017-04-12" version="1">MSELTYLVVGLGNPGLTYDATRHNVGFWAVADLADRYGSGFSLNTRQRAEIATVVLPGAAPAKLVLAKPTTYMNESGAAVRAVAAFHKIPVERVIAIHDELDLDPGQLRVKLGGGDNGHNGLKSMRAHLGSGDFYRVRVGIGRPAGRQPAADYVLAKLKPADLDAMRVDAAVAADAVESLVREGLTSTQNRFNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGK0</accession>
    <name>A0A1Q2CGK0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45234">
        <property type="protein sequence ID" value="AQP45234"/>
        <property type="gene ID" value="RPIT_10870"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10870"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="139" mass="15173" checksum="00DB38C49D18AB01" modified="2017-04-12" version="1">MGRGLSPQQRALLEALGAHDVDAVWAGPWRRSAKRLVRRGLARAIYLRKQDRSGRMVAHLALTAPDSQLQGDAYPLGSPGWVDAPPPSLLTFGTRLQALVVGQSLDRPVSKFYVTSWAAEERRAHSAVVQVAVPRELDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGL8</accession>
    <name>A0A1Q2CGL8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MarR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">RPIT_10940</name>
        <name evidence="3" type="ORF">SAMN05428934_102115</name>
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    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY51511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10940"/>
    <dbReference type="EnsemblBacteria" id="AQP45247">
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        <property type="gene ID" value="RPIT_10940"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY51511">
        <property type="protein sequence ID" value="SDY51511"/>
        <property type="gene ID" value="SAMN05428934_102115"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10940"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0003700">
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        <property type="evidence" value="ECO:0007669"/>
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            <begin position="23"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY51511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="164" mass="17858" checksum="49E41E92CF92BC56" modified="2017-04-12" version="1">MADEVDHVVSAWGRERADLALGPMHVWSRISRLSAVLDGHRKRAFSEHGIEGWEFDVLAALRRAGAPYQLSPGQLLRETHVTSGTMTNRVDRLVARGAVTRDPDPADGRGVLVSLTDAGLALVDAALATLVEVEESLLDGWPDEEREQLADFLRRLLTATTAGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
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        </submittedName>
    </protein>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </reference>
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        <location>
            <begin position="289"/>
            <end position="670"/>
        </location>
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        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
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        <source>
            <dbReference type="EMBL" id="AQP45282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY50268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="859" mass="94821" checksum="F200F0A92D492F8D" modified="2017-04-12" version="1"> </sequence>
</entry>
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        <submittedName>
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    <gene>
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        <lineage>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">RP1T</strain>
        </source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="554" mass="61901" checksum="304F7BA4D948994F" modified="2017-04-12" version="1"> </sequence>
</entry>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="entry name" value="BPL_LplA_LipB"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="1">
        <location>
            <begin position="128"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY48223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="349" mass="38515" checksum="4D92B079BE478236" modified="2017-04-12" version="1">MRGEYKVPGGKLVAVDVQTEDGRLTEAFISGDFFLEPDEALDDINGALLGMPENASVADLAAAITARLSPETRMIGFNAEAVGIAVRRALGHATDWSDHTFDVIGPVTMDPRMHVALDEVIAGELARGEINPSLRIWDWDQPLVVIGSFQSYRNEIDDEGRAKHGINVVRRITGGGAMFMEPGNCVTYSLVVPASLVEGLSFERSYEFLDQWVMGALAELGVNARYVPLNDIASDEGKIAGAAQRRVTGGVVVHHVTMAYDIDADKMLEVLRIGREKLSDKGTKSANKRVDPLRSQTQLPRDEILEAFLTHFEGRYETARRDYTDDELAKAKHLVETKFSSDEWTKRIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH18</accession>
    <name>A0A1Q2CH18_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_11535</name>
        <name evidence="6" type="ORF">SAMN05428934_106168</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY94398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45350">
        <property type="protein sequence ID" value="AQP45350"/>
        <property type="gene ID" value="RPIT_11535"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY94398">
        <property type="protein sequence ID" value="SDY94398"/>
        <property type="gene ID" value="SAMN05428934_106168"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11535"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY94398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="74" mass="8445" checksum="D2D659928006CFC7" modified="2017-04-12" version="1">MDWCAPPSGVSDTPRRRNGEDERGRRLAETAPSDLLIATAIAERDPEGARFLMMRHVRTTREWLEGIWPEPLVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH32</accession>
    <name>A0A1Q2CH32_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Transpeptidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11945"/>
    <dbReference type="EnsemblBacteria" id="AQP45422">
        <property type="protein sequence ID" value="AQP45422"/>
        <property type="gene ID" value="RPIT_11945"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11945"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transpeptidase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="76" mass="7983" checksum="0800DF70060CF3AE" modified="2017-04-12" version="1">MLQTMMKATVDSGTDKSLKGVMTGAKTGTAQWGKAGALQTHAWMIAYNDKYAVASFVEVGDSGGSTAAPLILQLFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH55</accession>
    <name>A0A1Q2CH55_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">N-formylglutamate amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_12040</name>
        <name evidence="2" type="ORF">SAMN05428934_10667</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12040"/>
    <dbReference type="EnsemblBacteria" id="AQP45441">
        <property type="protein sequence ID" value="AQP45441"/>
        <property type="gene ID" value="RPIT_12040"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92119">
        <property type="protein sequence ID" value="SDY92119"/>
        <property type="gene ID" value="SAMN05428934_10667"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12040"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007709">
        <property type="entry name" value="N-FG_amidohydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05013">
        <property type="entry name" value="FGase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY92119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="253" mass="28526" checksum="E0A7374C567CF320" modified="2017-04-12" version="1">MDAYEFRGDWSGQLIASAIHAGHDLRPEVADLMILDEADRLREEDPHTDRIAARAPAQIVVHRSRFEMDLNRVREKTVYRSPADCWDLDVWSSGSLPDDVVERSMEEYDSFFAALAERLDEVAARGPFVLYDIHSYNHRRDGADAEPAPAEENPEVNLGTGSVDHVTFGAVVGAFRQTMLDEGFDVRDNVKFLGQNLAWFVHGRYPGVGCVLAIEFKKTFMDEWTGEVDEDHLTRLGDAIEKSFGPVLEAMPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH79</accession>
    <name>A0A1Q2CH79_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyltransferase (GNAT) family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12205</name>
        <name evidence="3" type="ORF">SAMN05428934_10635</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY91448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45472">
        <property type="protein sequence ID" value="AQP45472"/>
        <property type="gene ID" value="RPIT_12205"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY91448">
        <property type="protein sequence ID" value="SDY91448"/>
        <property type="gene ID" value="SAMN05428934_10635"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12205"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY91448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="205" mass="22082" checksum="D71D3B909096AA98" modified="2017-04-12" version="1">MSPTIRPATKDDLPAASALFGAAFETTPQWRWMIEDDEARHAVLPSLLRSTLAQGLARGRLVVADDDGALAGVACWMAPGKWRVPAWRGATSVREVIPHVRSGALLGFIERGRVVDGAAKAAHPAEPHWYLGGVAVAPSEQGRGLGAQLIREGLSHTGQLPVYLECEEGLAHYYETFGFRRRHRIDPGGGAPAQAGMWLEPDFGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH85</accession>
    <name>A0A1Q2CH85_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA-specific adenosine deaminase</fullName>
            <ecNumber evidence="3">3.5.4.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tadA</name>
        <name evidence="5" type="ORF">RPIT_12260</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>adenosine(34) in tRNA + H(+) + H2O = inosine(34) in tRNA + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:43168"/>
            <dbReference type="Rhea" id="RHEA-COMP:10373"/>
            <dbReference type="Rhea" id="RHEA-COMP:10374"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:82852"/>
            <dbReference type="EC" id="3.5.4.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.33" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12260"/>
    <dbReference type="EnsemblBacteria" id="AQP45479">
        <property type="protein sequence ID" value="AQP45479"/>
        <property type="gene ID" value="RPIT_12260"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12260"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002100">
        <property type="term" value="P:tRNA wobble adenosine to inosine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00972">
        <property type="entry name" value="tRNA_aden_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028883">
        <property type="entry name" value="tRNA_aden_deaminase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14437">
        <property type="entry name" value="MafB19-deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="4">
        <location>
            <begin position="3"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="157" mass="16453" checksum="3CAEABC3B9A75634" modified="2017-04-12" version="1">MGTRWHAAMGEALAEAVAAEAHGDVPIGAVILDAEGRVIARGGNERELTGDPTSHAEIVAIRRAAEALGEWRLTGCTIVVTLEPCTMCAGAIVAARLDRLVFGAFDEKAGAVSSLWDVVRDPRLNHRPLVTSGVMASECANVLGGFFAERRSSSSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHE3</accession>
    <name>A0A1Q2CHE3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Guanine deaminase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">tRNA-specific adenosine deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12635</name>
        <name evidence="3" type="ORF">SAMN05428934_104159</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY79437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12635"/>
    <dbReference type="EnsemblBacteria" id="AQP45546">
        <property type="protein sequence ID" value="AQP45546"/>
        <property type="gene ID" value="RPIT_12635"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY79437">
        <property type="protein sequence ID" value="SDY79437"/>
        <property type="gene ID" value="SAMN05428934_104159"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12635"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY79437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="151" mass="15858" checksum="8536AB599D04C0F6" modified="2017-04-12" version="1">MTDHLQRAIDLAVGNVADGGGPFGAVVVAPSGKEFTGVNRVTAIPDPTAHAEVQAIRAAAVGLGTHDLTGCILYTSCEPCPMCLGAALWARVSTVVFAADRHDAAAVGFDDAAFHTEVAEGVTALECAREPHPEALAPFQAWERFEERINY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHG2</accession>
    <name>A0A1Q2CHG2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator, OmpR family, contains REC and winged-helix (WHTH) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_12455</name>
        <name evidence="6" type="ORF">SAMN05428934_104194</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY80382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12455"/>
    <dbReference type="EnsemblBacteria" id="AQP45513">
        <property type="protein sequence ID" value="AQP45513"/>
        <property type="gene ID" value="RPIT_12455"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY80382">
        <property type="protein sequence ID" value="SDY80382"/>
        <property type="gene ID" value="SAMN05428934_104194"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12455"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="4"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="125"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="125"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY80382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="228" mass="24715" checksum="1B875CDA83634E54" modified="2017-04-12" version="1">MSPTVLVVDDEPDIASLLRRYLETDGMSVLTAATGAEALRQVERADVVLLDLGLPDQSGLDVLARIRATSSVYVMVVTARAEEVDRIVGLSLGADDYIVKPFSPREVVARVHALLRRPRGEGPSDSSLSFGELAIDPERREVTVEGQQVALSALDFDLLLALARKPGRVFSRGQLLEQVWGYDFYGDERVVDVHIRTIRAALGEAAAGFVGTVRGVGYRFLPDPGGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHH1</accession>
    <name>A0A1Q2CHH1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_12695</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12695"/>
    <dbReference type="EnsemblBacteria" id="AQP45557">
        <property type="protein sequence ID" value="AQP45557"/>
        <property type="gene ID" value="RPIT_12695"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12695"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PTHR13832"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="3">
        <location>
            <begin position="6"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="495" mass="52338" checksum="25ECA4D5712BE9E9" modified="2017-04-12" version="1">MMYSLRFAAHSEVGRIRKNNQDGGYASPNLLMVADGMGGAAAGDLASAVAATEAARSDHRTLDPEEMLESIAGMVARANSKLTDLIDEDLELDGMGTTFCGAMFNGEQFGIAHVGDSRGYLLRDGTLTQLTHDHSWVQSLIDEGKITPQQAATHPHRSLILKVLNGQVNFEPDLELIDAKLGDRIMFCSDGLSGLISEAQILQFMSLDDADEAIAEMARAANAAGGHDNITVIIGDVVEQDDDLDAAPGVLVGSANEVEIPRTGQLAQAKGTVDKQPQYPPTSNDTPIEHDETEVARYAPQESKHRWPGIIALVLAVALVIGGSVWGVQAYSKTRYFVSADDGVVAIYNGLPGSFLGVDFATIAERTDTRVSDLPKFYQQQVESAIPVSSLEAGRATAGQLAARAEECIQTREDRNKPKPTPSPSPSPSPSPSPSASPSPAPGLPTTTAAPLPGVISDNPPVPAATRTYLFPRPTPSPSPSPSESPTPVTDPEDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHJ2</accession>
    <name>A0A1Q2CHJ2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_12870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12870"/>
    <dbReference type="EnsemblBacteria" id="AQP45588">
        <property type="protein sequence ID" value="AQP45588"/>
        <property type="gene ID" value="RPIT_12870"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12870"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="224" mass="23307" checksum="34402D87FA2B0C89" modified="2017-04-12" version="1">MLRAELYEGDTLVARDEADVIVTSAAFAGAQGPTVAVAEPAMRAWAEKLGFDTIDVASLDLTTPAPGVVWVTAHFGADAQRYARNGGRVLVLAEDADALGGAFDLLTFARLKPRSEDGDWVPRTDWLHRSGPFAAIPGDTVLGIAFEDILGDLVIKSGIPNAIRPAVVASGLFNGWLQGAASTTVSTAYSQGVVTVSTYRLRATVDSVPVSAPLGRALVMAAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHN6</accession>
    <name>A0A1Q2CHN6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13055</name>
        <name evidence="3" type="ORF">SAMN05428934_10476</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45621">
        <property type="protein sequence ID" value="AQP45621"/>
        <property type="gene ID" value="RPIT_13055"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY77110">
        <property type="protein sequence ID" value="SDY77110"/>
        <property type="gene ID" value="SAMN05428934_10476"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13055"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY77110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="93" mass="9785" checksum="5D2609E970AB3DBC" modified="2017-04-12" version="1">MDDASEINDDLHRRVRALRHLRTAARVVAVLAALIAVAWLVAAFAALAGSLDISPELAFVMAALSALLTGMAAHVGWVLAPRGVATLESRLDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHP6</accession>
    <name>A0A1Q2CHP6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13115</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13115"/>
    <dbReference type="EnsemblBacteria" id="AQP45631">
        <property type="protein sequence ID" value="AQP45631"/>
        <property type="gene ID" value="RPIT_13115"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13115"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046112">
        <property type="entry name" value="DUF6049"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19516">
        <property type="entry name" value="DUF6049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012275591" evidence="2">
        <location>
            <begin position="30"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="593"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="629" mass="66613" checksum="7C8861F60325B0E1" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHQ1</accession>
    <name>A0A1Q2CHQ1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13135</name>
        <name evidence="3" type="ORF">SAMN05428934_10460</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY76670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13135"/>
    <dbReference type="EnsemblBacteria" id="AQP45634">
        <property type="protein sequence ID" value="AQP45634"/>
        <property type="gene ID" value="RPIT_13135"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY76670">
        <property type="protein sequence ID" value="SDY76670"/>
        <property type="gene ID" value="SAMN05428934_10460"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13135"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022062">
        <property type="entry name" value="DUF3618"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12277">
        <property type="entry name" value="DUF3618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY76670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="223" mass="23319" checksum="2785000E741A6AF0" modified="2017-04-12" version="1">MSNPDEIRADIARTRAELSENVNALGDSTKPGNIVRSQVDDVKEGARNLKERIFGSNDDPYDQYATSNTGPGVRDKASALMDDAGQAVSDAPMKVKSSTRGNPLAAGLVAAGIGALIGGLIPPTRFEKEKASEIADQAQPLVDEVKQLATEAKDNLAPLASEAAESVKGTAQTAADEVKTEATSAKDEVADQAKSSADNVKADAQSAVDETKSEVDEKRDSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHR1</accession>
    <name>A0A1Q2CHR1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Isopentenyl-diphosphate Delta-isomerase</fullName>
            <shortName evidence="7">IPP isomerase</shortName>
            <ecNumber evidence="3 7">5.3.3.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">IPP:DMAPP isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Isopentenyl pyrophosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">idi</name>
        <name evidence="9" type="ORF">RPIT_13200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>isopentenyl diphosphate = dimethylallyl diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23284"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="EC" id="5.3.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="7">Binds 1 Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from isopentenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the IPP isomerase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="5.3.3.2" evidence="3 7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13200"/>
    <dbReference type="EnsemblBacteria" id="AQP45647">
        <property type="protein sequence ID" value="AQP45647"/>
        <property type="gene ID" value="RPIT_13200"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13200"/>
    <dbReference type="UniPathway" id="UPA00059">
        <property type="reaction ID" value="UER00104"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004452">
        <property type="term" value="F:isopentenyl-diphosphate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050992">
        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02885">
        <property type="entry name" value="IPP_Isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00202">
        <property type="entry name" value="Idi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011876">
        <property type="entry name" value="IsopentenylPP_isomerase_typ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02150">
        <property type="entry name" value="IPP_isom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 7" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0464">Manganese</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="8">
        <location>
            <begin position="39"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="548" mass="58612" checksum="BC3377763A028C99" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHV0</accession>
    <name>A0A1Q2CHV0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Tellurite resistance protein TerC</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_13220</name>
        <name evidence="8" type="ORF">SAMN05428934_10443</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TerC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY76187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13220"/>
    <dbReference type="EnsemblBacteria" id="AQP45650">
        <property type="protein sequence ID" value="AQP45650"/>
        <property type="gene ID" value="RPIT_13220"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY76187">
        <property type="protein sequence ID" value="SDY76187"/>
        <property type="gene ID" value="SAMN05428934_10443"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13220"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005496">
        <property type="entry name" value="Integral_membrane_TerC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022369">
        <property type="entry name" value="Integral_membrane_TerC_rswitch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30238:SF0">
        <property type="entry name" value="PTHR30238:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03741">
        <property type="entry name" value="TerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03718">
        <property type="entry name" value="R_switched_Alx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP45650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY76187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="396" mass="44048" checksum="3ED92E90AED7B06D" modified="2017-04-12" version="1">MTNVPLWIWGITIVVILGLLAFDFIFHVRKAHVPTLREAAIWSAIYVGLAIVFGILVWAFGGAQMGAEYFGGYITEKALSVDNLFVFLIIISSFAVPREDQQKVLLFGIVFALIARTAFIFAGKAIIDNFSWAFYLFGLILIVTAGKLLAPEKEGDDEANNFIIRLAKKYLHTTDHYDGDKLFTYENGKRVLTPMLLVMVAIGGTDILFALDSIPAIYGLTTNVYIVFTATAFSLMGLRQLYFLIDGLLDRLVYLNYGLAFILGFIGVKLVLHALHENQLPFINGGEPVPVFEIEISHSLIVILVSLLVTVVASLASPMGKVKTAVRNVERHAISYLHTEYHGTESDHESTYQDMLKAAERLKGLDPERVEQMMDETGTYEVVQKAHALRASLRHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHW6</accession>
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            <fullName evidence="1">Putative membrane protein insertion efficiency factor</fullName>
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        <name evidence="4" type="ORF">SAMN05428934_11181</name>
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
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            <taxon>Propionibacteriales</taxon>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
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            <strain evidence="3 5">RP1T</strain>
        </source>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Could be involved in insertion of integral membrane proteins into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0161 family.</text>
    </comment>
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        <property type="protein sequence ID" value="AQP45716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13590"/>
    <dbReference type="EnsemblBacteria" id="AQP45716">
        <property type="protein sequence ID" value="AQP45716"/>
        <property type="gene ID" value="RPIT_13590"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ13064">
        <property type="protein sequence ID" value="SDZ13064"/>
        <property type="gene ID" value="SAMN05428934_11181"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13590"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ13064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="94" mass="10485" checksum="250DC780F259915B" modified="2017-04-12" version="1">MLKQPLIWFIKAWRAVISPAYGDVCKFHPTCSAYGLRAVETHGALRGSWLTGRRLVRCHPWSAGGVDYVPGTPEADAWAHENSNEHGAHQPQTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHY3</accession>
    <name>A0A1Q2CHY3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative ABC transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_13630</name>
        <name evidence="10" type="ORF">SAMN05428934_11173</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45722">
        <property type="protein sequence ID" value="AQP45722"/>
        <property type="gene ID" value="RPIT_13630"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12928">
        <property type="protein sequence ID" value="SDZ12928"/>
        <property type="gene ID" value="SAMN05428934_11173"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13630"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="415"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="443"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="499"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="727"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="780"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="814"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="17"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="302"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
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            <end position="696"/>
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            <begin position="756"/>
            <end position="846"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        </source>
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            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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    </evidence>
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            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45722.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDZ12928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="854" mass="88861" checksum="77429DA3EF10CA85" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHY7</accession>
    <name>A0A1Q2CHY7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45736">
        <property type="protein sequence ID" value="AQP45736"/>
        <property type="gene ID" value="RPIT_13745"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13745"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="65" mass="7153" checksum="CA7B721E8A53F99F" modified="2017-04-12" version="1">MSTAKVTTTRRRRPDAKCPLRPGEPCTLCQACVTGPQDCGLVYLIMDDPEAREAFAQSKRVAADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI06</accession>
    <name>A0A1Q2CI06_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transketolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transketolase subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13870</name>
        <name evidence="3" type="ORF">SAMN05428934_11126</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13870"/>
    <dbReference type="EnsemblBacteria" id="AQP45759">
        <property type="protein sequence ID" value="AQP45759"/>
        <property type="gene ID" value="RPIT_13870"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12072">
        <property type="protein sequence ID" value="SDZ12072"/>
        <property type="gene ID" value="SAMN05428934_11126"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13870"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transket_pyr" evidence="1">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ12072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="307" mass="32843" checksum="2DAC04285A505287" modified="2017-04-12" version="1">MRDRFVSTLMGLAEKDPNVHLVTGDLGFGVLKPFWERFPDQFTNAGIAEQNMTSFAAGMALEGRTVFTYSIGNFPTLRAIEQIRNDCAYHEANVKIVCVGGGFTYGSLGMSHHATEDLAIMRALPNVTVMAPSDAAQAQLATEAIYAQPGTCYLRLGRGGEPNLGTPAEEFEIGKALPVSDGEGVALLFTGAIGDEVIEARDTLAADGHQVAVVSFPTVKPIDVEAIVNLAQRFDTLVTVEEHNVVGGLGGSVAEVLAELPSPRARLARVGLDDRYSSIVGTQKYLRDAYGMSARAITERVRQVLNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI14</accession>
    <name>A0A1Q2CI14_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal RNA small subunit methyltransferase G</fullName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">16S rRNA 7-methylguanosine methyltransferase</fullName>
            <shortName evidence="2">16S rRNA m7G methyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rsmG</name>
        <name evidence="3" type="ORF">RPIT_13575</name>
        <name evidence="4" type="ORF">SAMN05428934_11184</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically methylates the N7 position of a guanine in 16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ13109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13575"/>
    <dbReference type="EnsemblBacteria" id="AQP45713">
        <property type="protein sequence ID" value="AQP45713"/>
        <property type="gene ID" value="RPIT_13575"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ13109">
        <property type="protein sequence ID" value="SDZ13109"/>
        <property type="gene ID" value="SAMN05428934_11184"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13575"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070043">
        <property type="term" value="F:rRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00074">
        <property type="entry name" value="16SrRNA_methyltr_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003682">
        <property type="entry name" value="rRNA_ssu_MeTfrase_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31760">
        <property type="entry name" value="PTHR31760"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02527">
        <property type="entry name" value="GidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00138">
        <property type="entry name" value="rsmG_gidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="2">
        <location>
            <begin position="124"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ13109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="206" mass="22391" checksum="3C0958F71E2854F7" modified="2017-04-12" version="1">MSDDRTSRDAIEQAYPQSFKELCGYVDILASRGIEWGLLGPREGDRLWSRHIANSLALVDPIPLGVTVVDVGSGAGLPGLPLALARTDLGVTLVEPLLRRSNFLELAVDELGIGERVRVLRARAEETKERFDVVVCRAVAPLDKLLRWTTPLLEPGGQLIALKGESAEDEIRGASPLLKKLGLRAEVLELRAAQGVDGTRAIRVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI35</accession>
    <name>A0A1Q2CI35_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sulfate adenylyltransferase/protein-tyrosine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_14055</name>
        <name evidence="5" type="ORF">SAMN05428934_1179</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the low molecular weight phosphotyrosine protein phosphatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000017">
        <property type="protein sequence ID" value="SDZ20844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14055"/>
    <dbReference type="EnsemblBacteria" id="AQP45786">
        <property type="protein sequence ID" value="AQP45786"/>
        <property type="gene ID" value="RPIT_14055"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ20844">
        <property type="protein sequence ID" value="SDZ20844"/>
        <property type="gene ID" value="SAMN05428934_1179"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14055"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017867">
        <property type="entry name" value="Tyr_phospatase_low_mol_wt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00719">
        <property type="entry name" value="LMWPTPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="LMWPc" evidence="3">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ20844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="155" mass="17258" checksum="A5A8BA85182F4539" modified="2017-04-12" version="1">MRWVFVCTANISRSPYAERRMAQLLGDTSAVEVASAGIPGFDGRPMDPQMAALLEVRGVDASDHASRILTEDILRDASLVLTMEFSHHMAILEKWPWATDRVRGLGQFAKSGQRNSMVWDIADPYRRGRGAAKKAAQQIDQYLTEILPLAQESAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIA9</accession>
    <name>A0A1Q2CIA9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_14385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45847">
        <property type="protein sequence ID" value="AQP45847"/>
        <property type="gene ID" value="RPIT_14385"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14385"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004260">
        <property type="entry name" value="Pyr-dimer_DNA_glycosylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03013">
        <property type="entry name" value="Pyr_excise"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="140" mass="15857" checksum="307D5F80151C76FB" modified="2017-04-12" version="1">MRLWSLHPTLLDRAALVAGWREGLLAQAVLAGRTKGYLNHPQLQRFRTTADPVRAVVTYLAGLRSEAAARGYRFDVTRLDTVPDDELRLTVTAGQLAYELDHLRSKVRLRAPDWEPRLTAPRPHPLFTVVDGPIEAWERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIB9</accession>
    <name>A0A1Q2CIB9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fructose-1-phosphate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_14360</name>
        <name evidence="5" type="ORF">SAMN05428934_11254</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ15214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14360"/>
    <dbReference type="EnsemblBacteria" id="AQP45844">
        <property type="protein sequence ID" value="AQP45844"/>
        <property type="gene ID" value="RPIT_14360"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ15214">
        <property type="protein sequence ID" value="SDZ15214"/>
        <property type="gene ID" value="SAMN05428934_11254"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14360"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017583">
        <property type="entry name" value="Tagatose/fructose_Pkinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000535">
        <property type="entry name" value="1PFK/6PFK/LacC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="27"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ15214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="306" mass="31340" checksum="B8F1581864CA24A1" modified="2017-04-12" version="1">MLHTVTLSPGFDDYYTVSGLDWGGVGTMHAYRSVASGKGVSCARSAAALGVPVVAHVAVGADDAGEYAARLDAEGLSHGLVTVPGSVRHNLTLVDGSGEKVAAHFMGERLRIDDPDAVEMLFDGVLASLQPDDIVTLNGSLAQGLADDAWAQLAAASLERGARVIVDAQGAALRACLAVRGITAFKPNDEEIRALPGLESLTADERVERALQFLDEAGATIPLVSLGARGVAVLREGRPAVLPSPADRAMVSVMAGDTFVAGLAWGLLRGADGEEVVRHGLAAAAAHVEGLAGASLRSRAEVLVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIE4</accession>
    <name>A0A1Q2CIE4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cation:H+ antiporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Sodium:calcium antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_14580</name>
        <name evidence="9" type="ORF">SAMN05428934_10998</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14580"/>
    <dbReference type="EnsemblBacteria" id="AQP45882">
        <property type="protein sequence ID" value="AQP45882"/>
        <property type="gene ID" value="RPIT_14580"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06472">
        <property type="protein sequence ID" value="SDZ06472"/>
        <property type="gene ID" value="SAMN05428934_10998"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14580"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004481">
        <property type="entry name" value="K/Na/Ca-exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10846">
        <property type="entry name" value="PTHR10846"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00367">
        <property type="entry name" value="TIGR00367"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="338"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="7">
        <location>
            <begin position="9"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="7">
        <location>
            <begin position="185"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="151"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ06472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="380" mass="38597" checksum="B782906F5EF6DE6C" modified="2017-04-12" version="1">MNLLDVGRIVLGLVLLVGGGELLVRGASDLAKRAGISSLVVGLTVVALATSAPELAVSVGATLNGQPDLAVGNVVGSNIVNILVILGLSALVLPLAVRQQLVRLDVPVMVGMTVVLLLVSLDGRISLADGTLLLALMAVHTVVTVWVSRRSPEADDHPGQTMDDSEQPSDEAGTGRRRPGVLLSAAFLAIGVGLLVLGAGQLVDGAVSIAEALGVSELVIGLTVVALGTSLPELATSLIAAVRGERDMAVGNIVGSNIANIGLVLGVPALISGNGLPVPPAALALDIPLMLAVAVALSPVVLTGFTVARWEGAMFLLLYGAYTAYLVLDAIGHDSLEGFTLVLVLFLLPLVVITLVATVGYELGVHAGRRQAKRGDELGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIE6</accession>
    <name>A0A1Q2CIE6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized conserved protein, DUF2236 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_14530</name>
        <name evidence="4" type="ORF">SAMN05428934_109109</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14530"/>
    <dbReference type="EnsemblBacteria" id="AQP45874">
        <property type="protein sequence ID" value="AQP45874"/>
        <property type="gene ID" value="RPIT_14530"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06686">
        <property type="protein sequence ID" value="SDZ06686"/>
        <property type="gene ID" value="SAMN05428934_109109"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14530"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018713">
        <property type="entry name" value="MPAB/Lcp_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09995">
        <property type="entry name" value="MPAB_Lcp_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
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        <source>
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        <source>
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        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="304" mass="33240" checksum="5FA17069F7A570F2" modified="2017-04-12" version="1">MNPVEKLRRLIGRTLRSRVAGADADAKALTIWHAPGPRWHSSDDIIWHLNGDAAMYPGGIRALLLQALHPAAMAGVAGHSGYRSDPWGRLQRTSEFLAMTTYGPIPSAEAIIARIRSVHERVRGKTDDGTPYRASDPHLLAWVHIAETQSFLAAFQHFGDRPLTQREADDYVAQAAPVGEMLGAVDLPRTEADLLAALEAYRPELRASADARDTVRFLLHEPPVPWPARPGYWMLAAGAISTMPVWAREELGLPTSRWFDRLLGLPLGKASTAIVRWALGPESRKGLASGQRRVPQPAQDAAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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            <dbReference type="PubMed" id="26869509"/>
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            <strain evidence="12 14">RP1T</strain>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
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        <subcellularLocation>
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    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14470"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="23"/>
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    <feature type="transmembrane region" description="Helical" evidence="8">
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        <location>
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        <location>
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        </location>
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        <source>
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        </source>
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            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13244"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP45863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDZ06932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="980" mass="104187" checksum="639952820A6E5240" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIJ3</accession>
    <name>A0A1Q2CIJ3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="508"/>
        </location>
    </feature>
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        <location>
            <begin position="18"/>
            <end position="71"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="537" mass="57162" checksum="B7C3914A6411F777" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIP5</accession>
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        <recommendedName>
            <fullName evidence="7">UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase</fullName>
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        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Meso-A2pm-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
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        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase</fullName>
        </alternativeName>
        <alternativeName>
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        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-N-acetylmuramyl-tripeptide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
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    </gene>
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + meso-2,6-diaminoheptanedioate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate</text>
            <dbReference type="Rhea" id="RHEA:23676"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7 8">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="7">Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the MurCDEF family. MurE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.13" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04005"/>
    <dbReference type="EnsemblBacteria" id="AQP46006">
        <property type="protein sequence ID" value="AQP46006"/>
        <property type="gene ID" value="RPIT_04005"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04005"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008765">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="P:regulation of cell shape"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MurE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
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        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
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        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005761">
        <property type="entry name" value="UDP-N-AcMur-Glu-dNH2Pim_ligase"/>
    </dbReference>
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        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01085">
        <property type="entry name" value="murE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 7 8" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 7 8" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7 8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="9">
        <location>
            <begin position="10"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="11">
        <location>
            <begin position="98"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="10">
        <location>
            <begin position="324"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-MurNAc-L-Ala-D-Glu binding" evidence="7">
        <location>
            <begin position="145"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Meso-diaminopimelate binding" evidence="7">
        <location>
            <begin position="398"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Meso-diaminopimelate recognition motif" evidence="7">
        <location>
            <begin position="398"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
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        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
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        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="100"/>
            <end position="106"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
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        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
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        <location>
            <position position="374"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
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        </ligand>
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        <location>
            <position position="450"/>
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        <ligand>
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            <name>meso-2,6-diaminoheptanedioate</name>
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        <location>
            <position position="212"/>
        </location>
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        <source>
            <dbReference type="ARBA" id="ARBA00005898"/>
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        <source>
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        <source>
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        <source>
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    </evidence>
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        <source>
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        </source>
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            <dbReference type="RuleBase" id="RU004135"/>
        </source>
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            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
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        <source>
            <dbReference type="EMBL" id="AQP46006.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="492" mass="51132" checksum="B9EE2067367E01B6" modified="2017-04-12" version="1">MGDTTADVSLTGITLDSRAVQPGWLYVALPGTRAHGAQFARSAVESGAGAILTDDEGLALLRREDVPVVAAADVRRVMAVMAARLFGEPARGMTMLGVTGTNGKTTTVALLQAGLAAAGVLCGTIGTIGFRLGDAEIPSTRSTVTTPESPDLQALLAVMSARGAEAVALEVSSHALALGRVEAIEFDVVGFLNLGRDHLDFHRDVDDYFEAKAALFEPGRSKVSVIWVDDPRGKELADRVAGHGASRLVTVGTAAGVDYRLECYRPVDPLGGTATVTRDGETLDLTLSLPGEYNMIDAAVSLAMLEAAGTPTDAALRGLRAAQVPGRMQRVPLDGPAPMVVVDFAHTPQAVSAAVESLAVLGPVITVLGCGGDRDADKRPHMGAAAARASALTIVTDDNPRSEPPEDIRAQTLAGARAAGGDVVEVPGRRAAIEEALRRAAPGTVVAILGKGHERGQILADRTVDFDDAQEATHAWRRLTEEGTQDAATLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIQ0</accession>
    <name>A0A1Q2CIQ0_9ACTN</name>
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        <submittedName>
            <fullName evidence="2">5-deoxy-glucuronate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03230"/>
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        <property type="protein sequence ID" value="AQP45991"/>
        <property type="gene ID" value="RPIT_03230"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
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        <property type="term" value="F:glucuronate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="term" value="P:inositol catabolic process"/>
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        <property type="entry name" value="KduI/IolB_isomerase"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04378">
        <property type="entry name" value="myo_inos_iolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="295" mass="32477" checksum="9985ED7B0EDACA4D" modified="2017-04-12" version="1">MSDNDKYVIRAGSTANGQYETDVSAQRAGWEWCSIRVLALSAGGAEALDSGEQELLVLPLQGGCVVEIDGREYELAGRTEVWTSITDYLYVPRHTAFTIRSADGGRFALPGSKATQDLPVRYCPASEVLTGLRGAGNCSRQVNNYALGNDVETSHLLVCEVLTPGGNWSSYPPHKHDEHTDVERVLEEIYYYEVRPAANGTTGMALQRIYPSPAGEIDVCAEVHSRDVVIMPFGYHGPSVAAPGYDLYYLNVMAGPAEGAAWLMTDDPHYTWLRQEWETDEVDPRLPMTPLNTQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIU0</accession>
    <name>A0A1Q2CIU0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome C biogenesis protein ResC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01715"/>
    <dbReference type="EnsemblBacteria" id="AQP45965">
        <property type="protein sequence ID" value="AQP45965"/>
        <property type="gene ID" value="RPIT_01715"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01715"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003834">
        <property type="entry name" value="Cyt_c_assmbl_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02683">
        <property type="entry name" value="DsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="DsbD" evidence="2">
        <location>
            <begin position="8"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="236" mass="24078" checksum="69A105A901B2C718" modified="2017-04-12" version="1">MLVALPVALLAGIVSFASPCVLPLLPGYLSYASGLGSAQIAEGTGSKKLLVGGTLGFVLGFSVIFVLTGAILGGVGAALLTNARAITIALGVVILVLGAGFAGWLPVPSGWRPSTAPRLGVWASPLLGMVFGLGWTPCIGPALSVVLTLALNEGSAVRGGVLAFAYALGLGLPFLAFAVAFTTLAPKLDWLRRHQQTMQRIGGVAMMAVGVAMIVGWWDALVAVLRQWAANFGTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIW3</accession>
    <name>A0A1Q2CIW3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP46013">
        <property type="protein sequence ID" value="AQP46013"/>
        <property type="gene ID" value="RPIT_04280"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04280"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="89" mass="9476" checksum="221A1BF65DB15673" modified="2017-04-12" version="1">MRLVPTAPGFWMLTLGVCIAALSPLFGFLVGVMSQRPEGEVPLDPLYLGLFIGVVVGGMGVLLAVVGGVRLWRHYKGVRVSTPQDVEAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIX2</accession>
    <name>A0A1Q2CIX2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TGc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03480"/>
    <dbReference type="EnsemblBacteria" id="AQP45995">
        <property type="protein sequence ID" value="AQP45995"/>
        <property type="gene ID" value="RPIT_03480"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03480"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013589">
        <property type="entry name" value="Bac_transglu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08379">
        <property type="entry name" value="Bact_transglu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TGc" evidence="1">
        <location>
            <begin position="179"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="310" mass="33767" checksum="A6C300496944BCCD" modified="2017-04-12" version="1">MAARRYFVKHRTSYLYSEPVTLCHERGFLTPRQAPSQTVLAHGTRVTPEPLLESVHTDRFGNTSHYLEIHYPHTQLEVVKEAIVDVAWPEIHTDQLDQWTLGSAQRAIAGNAALRLDRAMYGLPSRYVDAPGGLDAYADTILAPNLGFGQALVELTRGIHRDFAYRPGVTSVRTTVGELLDLRAGVCQDFTHLGLAILRSLGIPARYVSGYIETRPAPGKQKLEGSDASHAWISALAPNGAWIDVDPTNAQFADSRYIVTAWGRDFADVSPLRGVVVTEAASSRMSVGVDVLPMVGDDAPPISVLGLSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIZ1</accession>
    <name>A0A1Q2CIZ1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_04425</name>
        <name evidence="2" type="ORF">SAMN05428934_101491</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY36684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04425"/>
    <dbReference type="EnsemblBacteria" id="AQP46015">
        <property type="protein sequence ID" value="AQP46015"/>
        <property type="gene ID" value="RPIT_04425"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY36684">
        <property type="protein sequence ID" value="SDY36684"/>
        <property type="gene ID" value="SAMN05428934_101491"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04425"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021449">
        <property type="entry name" value="DUF3099"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11298">
        <property type="entry name" value="DUF3099"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP46015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY36684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="105" mass="11390" checksum="2EE3638EA2BBE2AC" modified="2017-04-12" version="1">MAKAPDSTLITSAGRSRSLDLEERQRRYLITMGVRTACFLLFLVVPGWWKLAALAGAALLPAFAVLFANSTDHRPPAVAPEMKEQEGLRALPASHVVTGTVEETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ19</accession>
    <name>A0A1Q2CJ19_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl transferase family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_10170</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10170"/>
    <dbReference type="EnsemblBacteria" id="AQP46119">
        <property type="protein sequence ID" value="AQP46119"/>
        <property type="gene ID" value="RPIT_10170"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10170"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009250">
        <property type="term" value="P:glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011875">
        <property type="entry name" value="M1P_synthase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02149">
        <property type="entry name" value="glgA_Coryne"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="4">
        <location>
            <begin position="15"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="3">
        <location>
            <begin position="192"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP46119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="393" mass="42495" checksum="F87E85BBF5E551E8" modified="2017-04-12" version="1">MKLSLLTREYPPSIYGGAGVHVAQLVPQLRKLIDVEVHCMGEPREGATAHAEDFPAGANAALRVLGADLSMAAAVGDVDVVHSHTWYANMAGHLAGLLRDIPHVVTSHSLEPHRPWKAEQLGGGYRVSSWAEKTAYEAADAVISVSAGMRRDVLESYPDLDPDKVHVVKNGIDTDEFRPDHGTDVVTGLGMDPDRPSVAFVGRITRQKGLVHLVRAAQQFDPDTQVVLLAGAPDTPEIAAEFETAFAELKAQRSAPVIWVADMLPRAAVRQVLTHATVFACPSIYEPLGIVNLEAMACETPVVATAVGGIPEVVKDGMTGLLVPYDPERAGDREFIDAFEAEFANKTNLLTRDQHMAQQFGKAGRQRCIDEFSWAKIAQETVDVYQAAINARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ85</accession>
    <name>A0A1Q2CJ85_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_11720</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11720"/>
    <dbReference type="EnsemblBacteria" id="AQP46143">
        <property type="protein sequence ID" value="AQP46143"/>
        <property type="gene ID" value="RPIT_11720"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11720"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP46143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="269" mass="28861" checksum="D13461B83ECD15EF" modified="2017-04-12" version="1">MIEFDSVSKVYPDGTVAVDNFSLTIPSHTTMVLLGSSGCGKTTLMRMVNRMVDPTSGQVRIDGDDVLSRDPVQLRRSIGYVLQSAGLLPHRTVGDNVATVPRLRGVPRRQALADAAQLLERVGLDPALAARYPGQLSGGQQQRVGVARALATDPNILLMDEPFGAVDPIVRRELQDELLRLQAELGKTIVFVTHDVDEAFRLGDQVAVLRPGADIAQLGTPAEILAEPADQFVRTFIGADRAERQLSVVTAHGRTLVVDGDGKALGVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CB99</accession>
    <name>A0A1Q2CB99_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-oxoacid:ferredoxin oxidoreductase subunit beta</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">2-oxoglutarate ferredoxin oxidoreductase subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00035</name>
        <name evidence="4" type="ORF">SAMN05428934_10938</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00035"/>
    <dbReference type="EnsemblBacteria" id="AQP43409">
        <property type="protein sequence ID" value="AQP43409"/>
        <property type="gene ID" value="RPIT_00035"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05329">
        <property type="protein sequence ID" value="SDZ05329"/>
        <property type="gene ID" value="SAMN05428934_10938"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00035"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPP_enzyme_C" evidence="2">
        <location>
            <begin position="70"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ05329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="353" mass="37424" checksum="79B0F7DA7C85D175" modified="2017-04-12" version="1">MSTTLTHTGLTGGLAGVPLAIEPANRKDFVSDQEVRWCPGCGDYAVLAAFQSLMPQLGVRRENTVIISGIGCSSRFPYYLDTYGVHSIHGRAPSIATGLAMSRPDLAVWVVTGDGDALSIGGNHLIHALRRNTNITILLFNNRIYGLTKGQYSPTSESGKQTKSSPAGSVDHPFNPVKLALGAEATFVARTVDSDRAHLKEVMTRAVGHRGASLVEIYQNCPIFNDGVFDGLKAPDSPAIISLRHGEPITFAGGAKSVVRDAVTGRLSVVPTTEVGGRTVVVHDEFSDDVTQAVAIASLTDSHGLSQSPIGIFRDVGRPVHDDAARAQVTMPAAADRISHLQSLVTGHDTWTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBE0</accession>
    <name>A0A1Q2CBE0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">O-acetyl-ADP-ribose deacetylase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">O-acetyl-ADP-ribose deacetylase (Regulator of RNase III), contains Macro domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00105</name>
        <name evidence="3" type="ORF">SAMN05428934_10924</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00105"/>
    <dbReference type="EnsemblBacteria" id="AQP43421">
        <property type="protein sequence ID" value="AQP43421"/>
        <property type="gene ID" value="RPIT_00105"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05001">
        <property type="protein sequence ID" value="SDZ05001"/>
        <property type="gene ID" value="SAMN05428934_10924"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00105"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002589">
        <property type="entry name" value="Macro_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01661">
        <property type="entry name" value="Macro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00506">
        <property type="entry name" value="A1pp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51154">
        <property type="entry name" value="MACRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Macro" evidence="1">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ05001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="176" mass="18057" checksum="240541622B893CED" modified="2017-04-12" version="1">MTTPALEAVLGDITTQRVDAIVNAANSSLLGGGGVDGAIHRAAGPGLVADCRQLRMTELPDGLPTGEAVATDAHRLPARWVIHTVGPNRHAGQSDPALLAACFRNSLTLASSLGARSIALPAVSAGIYGWDADEVAQVAVDAVRSTEAPGVELVRFVLFSARLLDAFKTALAPTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBH6</accession>
    <name>A0A1Q2CBH6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00365</name>
        <name evidence="4" type="ORF">SAMN05428934_10527</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY84120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43457">
        <property type="protein sequence ID" value="AQP43457"/>
        <property type="gene ID" value="RPIT_00365"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY84120">
        <property type="protein sequence ID" value="SDY84120"/>
        <property type="gene ID" value="SAMN05428934_10527"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00365"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY84120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="235" mass="25318" checksum="BE15B0BE8A9DCDA5" modified="2017-04-12" version="1">MSNQQWNSGSHEWRPSSDDAQQAPGWPQAPDPTREWERQQPQAASQEWQPQGEADTHEWRPQTTGSGDVHASQDWYTSAPGWQGQGGAQQPQAHGWQGQPPGQDWQAQQAGPAWQQGGGQWPAQQSEWAQQGWGQPPAAPQARSTAKAEASGLFDFSFRKLALPGSAGLIFTIGVAAVAAEWLFRVVGLLMSEFAPGMAVVEALVVGLAAAVFKILVLRVLIEIGVALISRNTGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBK2</accession>
    <name>A0A1Q2CBK2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase involved in cell wall bisynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00515</name>
        <name evidence="3" type="ORF">SAMN05428934_10556</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY84915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00515"/>
    <dbReference type="EnsemblBacteria" id="AQP43486">
        <property type="protein sequence ID" value="AQP43486"/>
        <property type="gene ID" value="RPIT_00515"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY84915">
        <property type="protein sequence ID" value="SDY84915"/>
        <property type="gene ID" value="SAMN05428934_10556"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00515"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
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        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="287"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY84915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="850" mass="93479" checksum="CADF1276D366D858" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBR4</accession>
    <name>A0A1Q2CBR4_9ACTN</name>
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        <recommendedName>
            <fullName evidence="1">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00890"/>
    <dbReference type="EnsemblBacteria" id="AQP43553">
        <property type="protein sequence ID" value="AQP43553"/>
        <property type="gene ID" value="RPIT_00890"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00890"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="1">
        <location>
            <begin position="27"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="159" mass="17260" checksum="7C7D88B06899C273" modified="2017-04-12" version="1">MEAEAIMTSNDAYSSRDTELLPGSIEQYIDDDVPTCRPDATIEQIRATLTGRTFASVDEVAVLTDNGIPRLVGLIPIGTALAATPSLTAADVMDSDPPVIHRGFNEEQAAWKAVRHGESSLAVVDDCRGPWLKPGGTPRSAADRWPRSSRTCCRYWRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBT0</accession>
    <name>A0A1Q2CBT0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00945</name>
        <name evidence="4" type="ORF">SAMN05428934_105141</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">RP1T</strain>
        </source>
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    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43562">
        <property type="protein sequence ID" value="AQP43562"/>
        <property type="gene ID" value="RPIT_00945"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87179">
        <property type="protein sequence ID" value="SDY87179"/>
        <property type="gene ID" value="SAMN05428934_105141"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00945"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="DUF6326"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19851">
        <property type="entry name" value="DUF6326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY87179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="166" mass="18335" checksum="74822DC3BFE0D54E" modified="2017-04-12" version="1">MTVRTDTPILLDATPVPVQAKLAAAWTSFMFLYIYVDYFHLYKPGVVDNLRAGVVFEFDISPTLLTAMLASVAMPALMVMLSMTLPARVNRATNLVAASLYIPYSVVNAVGESWEWAFFYGLSIGLEVLLLAFILRAAWTWPRRTASPAPRAAGLDGEPHRTPQQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBW2</accession>
    <name>A0A1Q2CBW2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycerol 3-phosphate dehydrogenase (Quinone) subunit C</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">sn-glycerol-3-phosphate dehydrogenase subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_01110</name>
        <name evidence="6" type="ORF">SAMN05428934_105173</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY88058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01110"/>
    <dbReference type="EnsemblBacteria" id="AQP43591">
        <property type="protein sequence ID" value="AQP43591"/>
        <property type="gene ID" value="RPIT_01110"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY88058">
        <property type="protein sequence ID" value="SDY88058"/>
        <property type="gene ID" value="SAMN05428934_105173"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01110"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009061">
        <property type="term" value="P:anaerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004017">
        <property type="entry name" value="Cys_rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017753">
        <property type="entry name" value="G3P_DH_GlpC_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02754">
        <property type="entry name" value="CCG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03379">
        <property type="entry name" value="glycerol3P_GlpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="19"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="64"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY88058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="419" mass="45601" checksum="025D4E3C1F096F69" modified="2017-04-12" version="1">MSDKRDERAKALRERLNNELQRMSLDMCVKCTICETACPVAAVTPLFSGPKFVGPQAERFRDDEPVDHSVDYCSSCGTCSVVCPQGVNVAELNSIARAVMKAEQGVPVRDQTITQTVLMGKAMTPVAPIANAVLDNKLARYAMEKVVGVHRNAPMPTARGESLHKWLKKRPSPTKPATRGALVYFHGCAGGYFEVDAAKKAIEVLEYLGYEVIVPEQGCCGLAEQSNGLFEKASASVRRLVDQLRSPGTDLTIISTAGSCTGMLKHEAHQILGIHDPELLDVGTRIREISEFLMELYEAGELPTDFQPVNMRLPYHAPCQLKSQGMGTPASDLLRLIPGLEVIDSNVTCCGIAGTYGLKKEKYEIAQAVGQPLFDIVQANNDGLAACDTETCRWQIEKSSGVETVHPIVLVHRAYGLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBZ1</accession>
    <name>A0A1Q2CBZ1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Monosaccharide ABC transporter ATP-binding protein, CUT2 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Sugar ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_01300</name>
        <name evidence="6" type="ORF">SAMN05428934_1089</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01300"/>
    <dbReference type="EnsemblBacteria" id="AQP43621">
        <property type="protein sequence ID" value="AQP43621"/>
        <property type="gene ID" value="RPIT_01300"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01054">
        <property type="protein sequence ID" value="SDZ01054"/>
        <property type="gene ID" value="SAMN05428934_1089"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01300"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="16"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="269"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="48"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDZ01054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="514" mass="55715" checksum="42FD08A0E64ECE86" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBZ6</accession>
    <name>A0A1Q2CBZ6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LacI family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Simple sugar transport system substrate-binding protein/ribose transport system substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01295</name>
        <name evidence="4" type="ORF">SAMN05428934_1088</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01295"/>
    <dbReference type="EnsemblBacteria" id="AQP43620">
        <property type="protein sequence ID" value="AQP43620"/>
        <property type="gene ID" value="RPIT_01295"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01034">
        <property type="protein sequence ID" value="SDZ01034"/>
        <property type="gene ID" value="SAMN05428934_1088"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01295"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544413" evidence="1">
        <location>
            <begin position="34"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="2">
        <location>
            <begin position="61"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ01034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="341" mass="36107" checksum="3008F230FC57A6AB" modified="2017-04-12" version="1">MQNLNRRTILGALAASALIPLAACGGESTTPSATSTTTAAGQETTGGAASGELIVLGFSQVGAESGWRAANTKSIQDTLTKENGFDLKFSDAQQKQENQITALRGYIAQGVDVIAFSPVVETGWDAVLQEAKDAGIPVILTDRAIDSEDDTLYESFIGSDFVLEGKMAGDWVKEQYDGQGYKIVELQGTTGSAPAIDRQTGFAEAIEGTDLEIIASQTGNFTRTEGKTVMEGFLQAHDKIDLVYAHNDDMGLGAIEAIEAAGLVPGEDIKIVTIDAVKDGMQALADGKINYIVECNPLLGPDLAELAKKVVAGEEVEKRIVVKDLAFDQEAAKEALPTRQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC30</accession>
    <name>A0A1Q2CC30_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoid-associated protein RPIT_01205</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01205</name>
        <name evidence="4" type="ORF">SAMN05428934_105190</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the YbaB/EbfC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY88425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01205"/>
    <dbReference type="EnsemblBacteria" id="AQP43605">
        <property type="protein sequence ID" value="AQP43605"/>
        <property type="gene ID" value="RPIT_01205"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY88425">
        <property type="protein sequence ID" value="SDY88425"/>
        <property type="gene ID" value="SAMN05428934_105190"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01205"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043590">
        <property type="term" value="C:bacterial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00274">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004401">
        <property type="entry name" value="YbaB/EbfC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33449">
        <property type="entry name" value="PTHR33449"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02575">
        <property type="entry name" value="YbaB_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004555">
        <property type="entry name" value="UCP004555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82607">
        <property type="entry name" value="SSF82607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00103">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY88425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="104" mass="10913" checksum="CC066B85FFD04B82" modified="2017-04-12" version="1">MFGDFDINSLMQQAQQLQADLERAQEELASKTFTATAGGELVSVELNGKGDIESLTIQPDAMDPDDPETLAALIIAAYRSAKSQVDSAAAEAMPAMPPMPGLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCA0</accession>
    <name>A0A1Q2CCA0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Dipeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02035</name>
        <name evidence="3" type="ORF">SAMN05428934_1014</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY22424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02035"/>
    <dbReference type="EnsemblBacteria" id="AQP43739">
        <property type="protein sequence ID" value="AQP43739"/>
        <property type="gene ID" value="RPIT_02035"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY22424">
        <property type="protein sequence ID" value="SDY22424"/>
        <property type="gene ID" value="SAMN05428934_1014"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02035"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="190"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY22424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="441" mass="46081" checksum="62697CDBBB466518" modified="2017-04-12" version="1">MSVTESVNAVLPSVIADLKRLIAIPSVSSLPEHHDDVLAAADTVADLLRGVGCPEVRLLDGGGKPAVYGHFPAPEGAPTVLLYAHYDVQPTGDAAGWTTDAFSPMEREGRLYARGSADDKGGIAVHLAALRAFDGKPPVGVKVFIEGEEEIGSPSMKDLLDAHPEETSADLFIIADSMNWQVGQPALTTTLRGLIDAVVTVSTLESGVHSGQYGGLVPDAVTALCRLLSTLHDEEGNVAIKGLVQDPDPEVDYDHDALRAEAGVLDGVELFGDGKASARMWTRPAVSIVGIDTTSIKDASNTLIPSARAKVSVRIAPSQDPVAAEAALREHLTANAPWGARVEIDPERGGSGTRIDLSDPRARVAVEALEEAFGVAPVEMGVGGSIPIANEFAERNPGSLVLLTAVVDPTSRMHGLNESLDMGDFAKAALAETILLANLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCB3</accession>
    <name>A0A1Q2CCB3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">C-type cytochrome biogenesis protein CcsB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Cytochrome c-type biogenesis protein CcsB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_01725</name>
        <name evidence="9" type="ORF">SAMN05428934_10893</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01725"/>
    <dbReference type="EnsemblBacteria" id="AQP43685">
        <property type="protein sequence ID" value="AQP43685"/>
        <property type="gene ID" value="RPIT_01725"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02694">
        <property type="protein sequence ID" value="SDZ02694"/>
        <property type="gene ID" value="SAMN05428934_10893"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01725"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002541">
        <property type="entry name" value="Cyt_c_assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017562">
        <property type="entry name" value="Cyt_c_biogenesis_CcsA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045062">
        <property type="entry name" value="Cyt_c_biogenesis_CcsA/CcmC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30071">
        <property type="entry name" value="PTHR30071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01578">
        <property type="entry name" value="Cytochrom_C_asm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03144">
        <property type="entry name" value="cytochr_II_ccsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_C_asm" evidence="7">
        <location>
            <begin position="88"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP43685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ02694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="303" mass="33009" checksum="4E1B3836BD4F3EEA" modified="2017-04-12" version="1">MTLSEWSYSAMVFGTVAYLVAFALHTVEWSAARGLAAVRPDDGTEDARRLRVDLFGRLGLAATVLAAILHIAAVVLRGVAAERPPWGNMYEFITSSLAFAVVIYLVGALRWGMRWLGLGVTLLFAIGLGAAVTQFYVDVAPLVPALHSVWFIIHIIAAAISGAAFNVGAVAAALYLVRESAERRAAVSGGELTGYLAKLPSAVKLDMISYRLHAFALPLWTFTIAAGAIWAQYAWGRFWNWDPKETWSFITWVVYVAYLHARATAGWRGRPVAIIALVGLVTFWFNFIGVNLLFSGLHSYAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCB6</accession>
    <name>A0A1Q2CCB6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-amylase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Alpha-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02070</name>
        <name evidence="3" type="ORF">SAMN05428934_10111</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY22622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02070"/>
    <dbReference type="EnsemblBacteria" id="AQP43746">
        <property type="protein sequence ID" value="AQP43746"/>
        <property type="gene ID" value="RPIT_02070"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY22622">
        <property type="protein sequence ID" value="SDY22622"/>
        <property type="gene ID" value="SAMN05428934_10111"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02070"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="1">
        <location>
            <begin position="13"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY22622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="538" mass="60207" checksum="585E90132F928243" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCI1</accession>
    <name>A0A1Q2CCI1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Molybdopterin converting factor, small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_02120</name>
        <name evidence="2" type="ORF">SAMN05428934_10122</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            </authorList>
        </citation>
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        <source>
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    </reference>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
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    </evidence>
    <sequence length="79" mass="8161" checksum="AB59524AF2BAA467" modified="2017-04-12" version="1">MEIRFFAGAAEAAGVDTMEMEVEGLTAAQVASRLADQNPRLARVLAVSSLLADGARISDLDADLTGTSRLDVLPPFAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
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    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
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        </source>
    </reference>
    <reference evidence="3 5" key="2">
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
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    <reference evidence="2" key="3">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
    </reference>
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    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY24975"/>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544427" evidence="1">
        <location>
            <begin position="34"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY24975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="245" mass="25914" checksum="072E50D1E3C903B6" modified="2017-04-12" version="1">MSIRSASRSIRASGTLAILALATLTALSSGAAAAPAQGAGVFKLTFSGYASMASWSTCPDLSAADVGDMCSGADVMAFYSSGREQAGSEFHLHDRKSGVVKIFSYTCTVADFEVDPGVVERTCLPATEEFGRAVDVDVAVDPRLDQTHATALVPVQVSDWVSGTGSEATVEVDVSFSGSGPTRRIDERTHVTDRYVMWLEGTKGWERDCQATATFDGVTVPGELVACSMSRVRQAEVRVYHGLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCL6</accession>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY26514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02705"/>
    <dbReference type="EnsemblBacteria" id="AQP43859">
        <property type="protein sequence ID" value="AQP43859"/>
        <property type="gene ID" value="RPIT_02705"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY26514"/>
        <property type="gene ID" value="SAMN05428934_101141"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02705"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:metalloendopeptidase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="NEPRILYSIN"/>
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    </dbReference>
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            <end position="391"/>
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        <location>
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            <end position="646"/>
        </location>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP43859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY26514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="649" mass="72136" checksum="E9563ABA936D4F32" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCM4</accession>
    <name>A0A1Q2CCM4_9ACTN</name>
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        </submittedName>
    </protein>
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    </gene>
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        <name type="scientific">Tessaracoccus flavus</name>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY24229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43795">
        <property type="protein sequence ID" value="AQP43795"/>
        <property type="gene ID" value="RPIT_02325"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY24229">
        <property type="protein sequence ID" value="SDY24229"/>
        <property type="gene ID" value="SAMN05428934_10165"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02325"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="360"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="205"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY24229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="409" mass="43681" checksum="7BC81B5C050F2F1C" modified="2017-04-12" version="1">MTTTTIDRDTSNAVVAGVDTHKDTHHVAVLAAGSGARLGDLQVPATPAGYERLLGFVASFGAIALVGVEGTNSYGAGLARYLAAADVTIREVIRPKRAQRRRGKSDPIDAYAAAQQALAEPEILPIAKTSDGPVEQIRVLMAVRRSAMKARIAAHRQITSLLITAPDAVRTRFAHLDSDPLIDTLAATRPGPAVNSVTAATGQALRRLARRHQNLTAEIADIDAELRILTTQSAPAMLATKGFGVITTATLLITAGDNPARLRTEASFAALSGAAPIPASSGKTTRHRLNRGGDRQANWALHQIALVRLSTDPRTKAYAAKLTAAGKSKKDVLRCLKRAIAREAWHLIVHPAPTPRIDDLRPLRHLRGLTLTQAAEHLGTVPARISELERGTRLNIQLANAYRDYLNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCN0</accession>
    <name>A0A1Q2CCN0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADH dehydrogenase subunit M</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">NADH-quinone oxidoreductase subunit M</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_02690</name>
        <name evidence="7" type="ORF">SAMN05428934_101138</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3">Membrane</location>
            <topology evidence="1 3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I subunit 4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY26429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02690"/>
    <dbReference type="EnsemblBacteria" id="AQP43857">
        <property type="protein sequence ID" value="AQP43857"/>
        <property type="gene ID" value="RPIT_02690"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY26429">
        <property type="protein sequence ID" value="SDY26429"/>
        <property type="gene ID" value="SAMN05428934_101138"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02690"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010227">
        <property type="entry name" value="NADH_Q_OxRdtase_chainM/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003918">
        <property type="entry name" value="NADH_UbQ_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43507">
        <property type="entry name" value="PTHR43507"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01437">
        <property type="entry name" value="NUOXDRDTASE4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01972">
        <property type="entry name" value="NDH_I_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="30"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="365"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="408"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="5">
        <location>
            <begin position="129"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY26429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="504" mass="53526" checksum="853D8F2C4BF67168" modified="2017-04-12" version="1">MTLPLLTILALVPIVGALVLFFLKGHTARLVGLGIALTTTILGVLAFVLHAGGQVLAEEVPWIPAVGAHYALDLDGMGAILVLMTVIIVPIVLLAEWHVGDQLDARWGTNVFFALALLLQGFALIVFMASDVLLFYLAFEATLIPTYFLIGGFGGPARRAAAIKFLIYSLAGGLVMLVAVAGVYAASAAQGGPSFLIGDLVDLEMSTGMGRWLFAGFFFAFAVKAPLVGLHTWLPDTAEQATPGTSTLLVGILDKIGTFGMIKICLQMFPEASQWATPVILVWAIVSVLYGAFMAFGAKDLLRLVSYTSISHFGFMVFGIFALTSQSLSGSIFYMLNHGLSTAAMFLVVGFLIRRRGSAHIDAFGGVQTVAPVLAGVLLISGLSALALPGMGSFVSEFLVMAGAWQRFPIHTAVITLGMVLAAVYVLRMYLRTMTGPVTEQVATHVTTDVTFREKAVIAPLLVLLVIFGFFPKPLLTVADDAAQRTMAVVGVDDPAPQVKEGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCP4</accession>
    <name>A0A1Q2CCP4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nitrite reductase (cytochrome; ammonia-forming)</fullName>
            <ecNumber evidence="2">1.7.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_02430</name>
        <name evidence="12" type="ORF">SAMN05428934_10184</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>6 Fe(III)-[cytochrome c] + 2 H2O + NH4(+) = 6 Fe(II)-[cytochrome c] + 8 H(+) + nitrite</text>
            <dbReference type="Rhea" id="RHEA:13089"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16301"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.7.2.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome c-552 family.</text>
    </comment>
    <dbReference type="EC" id="1.7.2.2" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY24817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02430"/>
    <dbReference type="EnsemblBacteria" id="AQP43815">
        <property type="protein sequence ID" value="AQP43815"/>
        <property type="gene ID" value="RPIT_02430"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY24817">
        <property type="protein sequence ID" value="SDY24817"/>
        <property type="gene ID" value="SAMN05428934_10184"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02430"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042279">
        <property type="term" value="F:nitrite reductase (cytochrome, ammonia-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00548">
        <property type="entry name" value="NrfA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003321">
        <property type="entry name" value="Cyt_c552"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30633">
        <property type="entry name" value="PTHR30633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02335">
        <property type="entry name" value="Cytochrom_C552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000243">
        <property type="entry name" value="Cyt_c552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="470"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP43815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY24817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="494" mass="55319" checksum="58E66A35B8BD6529" modified="2017-04-12" version="1">MSDDTGSSQVEPTPRRTSNRRIGFIIAAIALTAIVTAGITAILANVIERMGEARDSYTKVVDLDDTVVDPAVWGQNFPSQYDSYLKTSEMNGTTHAGSQPSEREATELDPRTITATSRLEEDPRLVDMWAGYPFAEDYRHARGHAYMLEDQRYTIRVADFEQPGTCLNCHASTVKLMNDLGDGDREAGFQAMNQMPYNEVTQLVDHPVACIDCHDPETMDLRVTRPAFEKGIAALKKSEGIDDYDVNRDATRQEMRTFVCGQCHVEYYFEKDTKELTFPWSKGLDIDEIWEYYGEDGHKDFTHATTGAEVVKAQHPEFDIFWSNSVHAANGVSCADCHMPYKSEGARKVTDHHIQSPLLAVNSSCMTCHHTSAEEMEDRVVSIQDQFIGTRDVAFDSLVALIRALETAQTDGTPAEQIDAAREFQNKASFYLDYVYSENSYGFHAPAYIQRILADSLDASRKGQLVLQGVDPESLEPSELSLENEQKTAERGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCP6</accession>
    <name>A0A1Q2CCP6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Polar amino acid transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_02895</name>
        <name evidence="7" type="ORF">SAMN05428934_101180</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY27605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02895"/>
    <dbReference type="EnsemblBacteria" id="AQP43889">
        <property type="protein sequence ID" value="AQP43889"/>
        <property type="gene ID" value="RPIT_02895"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY27605">
        <property type="protein sequence ID" value="SDY27605"/>
        <property type="gene ID" value="SAMN05428934_101180"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02895"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="60"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="61"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY27605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="315" mass="34561" checksum="92389A38BE8D7E8A" modified="2017-04-12" version="1">MSPSAPELIRARPVPRPGLWIWAAVVLVLVAMLVNGLVTNPNYHWDVVAEHLFDPRVLRAIGWTLILTVGAMAIGIVMAVTTAVMRMGSNPILRSVAWAYIWFFRGTPVYTQLLFWGLIAVLYPRLSLGIPFGPEFLVFDTQDVITAFVAALLGLGLNEGAYLSEIVRAGLNSVDKGQWEAASALGMKRSTTLWRIVIPQAMRVIVPPTGNETISMLKTTSLVTAVPFSLELTFVTMAIGNRNFLPLPLLIVAAIWYLLITSILMVGQHYLERYYGRGFDGDDQTRGSAKGMSKRQQSILAAGTVHADPNLEVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD00</accession>
    <name>A0A1Q2CD00_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative ABC transport system substrate-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Sugar ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03385</name>
        <name evidence="3" type="ORF">SAMN05428934_101277</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03385"/>
    <dbReference type="EnsemblBacteria" id="AQP43976">
        <property type="protein sequence ID" value="AQP43976"/>
        <property type="gene ID" value="RPIT_03385"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30644">
        <property type="protein sequence ID" value="SDY30644"/>
        <property type="gene ID" value="SAMN05428934_101277"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03385"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06325">
        <property type="entry name" value="PBP1_ABC_unchar_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007487">
        <property type="entry name" value="ABC_transpt-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35271">
        <property type="entry name" value="PTHR35271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04392">
        <property type="entry name" value="ABC_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544425" evidence="1">
        <location>
            <begin position="25"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY30644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="321" mass="33206" checksum="49D10E5759050043" modified="2017-04-12" version="1">MKLKALAALGVSAALALTACGGDAGNDGDYKIGIATIVAHPALDAVQEGFIEALAEAGYEEGVNIEFDRQNAQGDQSTLTNIANTFGSSDYDGFLAVATPTAQALSNVITDKPVVFAAVTDPVAAELVSSWEAPDANVTGVSDLNPMREQLELIQEALPEAATVGIIYTSSEVNSQVQFDEAEKAAAELGLEVVAATVTNSSEVQQAADSLDVDAYLIPTDNTVVSAAEAVIQVAETKQTPVFASDESTMERGAAAGLSVNYTQQGRDAAAALLKMLEGTSAADIPVETQKEFDLFVNTAAAEAQGLALPESIVSRATKQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD13</accession>
    <name>A0A1Q2CD13_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_03610</name>
        <name evidence="4" type="ORF">SAMN05428934_101323</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY32034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03610"/>
    <dbReference type="EnsemblBacteria" id="AQP44012">
        <property type="protein sequence ID" value="AQP44012"/>
        <property type="gene ID" value="RPIT_03610"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY32034">
        <property type="protein sequence ID" value="SDY32034"/>
        <property type="gene ID" value="SAMN05428934_101323"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03610"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021403">
        <property type="entry name" value="DUF3043"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11241">
        <property type="entry name" value="DUF3043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY32034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="218" mass="24527" checksum="8EC43B016AA1F0DC" modified="2017-04-12" version="1">MALFRPYERNESAKTDRIQSLTPKGEKAAAKAAAKTAPTAPAAAPEAENPGTRAGIRKKQGATPSRKAAEAARMERLHPTLSPKEQRRADARARSAARMDSWSRIEQSPERQLLRDYVDTRWTVAEFMLPLMILLMALSMISIQAAPQISYYVTLALWPLMIMAIINVAIMWRGFKKLLAERHPGASTKGLLMYMMNRSIMLRRFRQPGPRIKRGDPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD20</accession>
    <name>A0A1Q2CD20_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable cytosol aminopeptidase</fullName>
            <ecNumber evidence="8">3.4.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucine aminopeptidase</fullName>
            <shortName evidence="8">LAP</shortName>
            <ecNumber evidence="8">3.4.11.10</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Leucyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pepA</name>
        <name evidence="10" type="ORF">RPIT_03595</name>
        <name evidence="11" type="ORF">SAMN05428934_101320</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.</text>
            <dbReference type="EC" id="3.4.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>Release of an N-terminal amino acid, preferentially leucine, but not glutamic or aspartic acids.</text>
            <dbReference type="EC" id="3.4.11.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the peptidase M17 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.1" evidence="8"/>
    <dbReference type="EC" id="3.4.11.10" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY31946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03595"/>
    <dbReference type="EnsemblBacteria" id="AQP44009">
        <property type="protein sequence ID" value="AQP44009"/>
        <property type="gene ID" value="RPIT_03595"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY31946">
        <property type="protein sequence ID" value="SDY31946"/>
        <property type="gene ID" value="SAMN05428934_101320"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03595"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00181">
        <property type="entry name" value="Cytosol_peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023042">
        <property type="entry name" value="Peptidase_M17_leu_NH2_pept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008283">
        <property type="entry name" value="Peptidase_M17_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="PTHR11963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02789">
        <property type="entry name" value="Peptidase_M17_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTOSOL_AP" evidence="9">
        <location>
            <begin position="346"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="278"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="352"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY31946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="501" mass="51754" checksum="CB3F79497D2E0698" modified="2017-04-12" version="1">MTRTDPTLNLTKSLPRSADVLLLGLATIHQGDRALVGLSPELGKSYQKAYGRSLAELASAMGAKTALEEVTQLPPLGSTRVFVVGLGDADVTPHGLRGALGNALRCIAGLEDAQGLEVAVSLELSDPELIQAAAEGAVLGAYSFQPITGTAKPSPVASISFITPLTGTEQRTALTTAQHTAAAVCQARDWVNTPPNLLYPESFAEAAKTHVREQKVAVEILDEKALERGGYGGILAVGGGSARKPRLVRLSYAPRGAERHLALVGKGITFDSGGLDIKPAGQMAGMKYDMSGAAAVIAAVNAIAALGLKVKVTAYAALAENLPSGSAFRSGDVLTMFDGQTVENYNTDAEGRLVMADAIARAGQDKPDLIVDVATLTGACMVALGLRTGGLITNGEETSDLLLDAAEAAGEDFWELPLTDATREELKSTVADMKSGAGKRWGGALVAGAFLERFVGDGVAWAHLDIAGPAENPESAYGYVPKGGTGVGVRTIVTLAGLLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD73</accession>
    <name>A0A1Q2CD73_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome bc1 complex Rieske iron-sulfur subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Cytochrome bc1 reductase complex subunit QcrA</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Rieske iron-sulfur protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">RPIT_03710</name>
        <name evidence="17" type="ORF">SAMN05428934_101344</name>
    </gene>
    <organism evidence="16 18">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 18" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1T</strain>
        </source>
    </reference>
    <reference evidence="17 19" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">RP1</strain>
        </source>
    </reference>
    <reference evidence="16" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Rieske iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY32633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03710"/>
    <dbReference type="EnsemblBacteria" id="AQP44030">
        <property type="protein sequence ID" value="AQP44030"/>
        <property type="gene ID" value="RPIT_03710"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY32633">
        <property type="protein sequence ID" value="SDY32633"/>
        <property type="gene ID" value="SAMN05428934_101344"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03710"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045603">
        <property type="entry name" value="QcrA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014349">
        <property type="entry name" value="Rieske_Fe-S_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10134">
        <property type="entry name" value="PTHR10134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19297">
        <property type="entry name" value="QcrA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Rieske" evidence="15">
        <location>
            <begin position="263"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="AQP44030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="SDY32633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="354" mass="38460" checksum="52F301FBADB8EAE4" modified="2017-04-12" version="1">MSHDNLPVHDPDLGHSVANPGLEEHIPRYTDVNEGAGNRAYLAILTMLGLVPLLAIAFVVIYFAVPKDMVLDFGIIRASALNVGLGLTAGLAVTLIGVAVIQWARVLMGDEESVEFRHTAATSAEDRAALGALYDQGVEQSGVRRRKLLLGALGGALGISVVPALVLLADMGPHPTKRVREQTIERTIWAEDVVLVNDENWVKLRPEDIEIGQLVNAQPENLRELHGVEAHQAKAKAAIIVVRMDPNSIKIPESRKDWHVSGILAYSKICTHVGCPISLWERQTHHLLCPCHQSTFDLGNSGVPVFGPAARALPQLAIKVNQDGYLVAQGDFSVPVGPSYFERDSRNDFKDGDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD82</accession>
    <name>A0A1Q2CD82_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase</fullName>
            <ecNumber evidence="10">2.4.1.227</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">murG</name>
        <name evidence="13" type="ORF">RPIT_04030</name>
        <name evidence="14" type="ORF">SAMN05428934_101409</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-glucosamine = di-trans-octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1-&gt;4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + H(+) + UDP</text>
            <dbReference type="Rhea" id="RHEA:31227"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="ChEBI" id="CHEBI:61388"/>
            <dbReference type="EC" id="2.4.1.227"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the glycosyltransferase 28 family. MurG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.227" evidence="10"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY34335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04030"/>
    <dbReference type="EnsemblBacteria" id="AQP44083">
        <property type="protein sequence ID" value="AQP44083"/>
        <property type="gene ID" value="RPIT_04030"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY34335">
        <property type="protein sequence ID" value="SDY34335"/>
        <property type="gene ID" value="SAMN05428934_101409"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04030"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051991">
        <property type="term" value="F:UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050511">
        <property type="term" value="F:undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030259">
        <property type="term" value="P:lipid glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00033">
        <property type="entry name" value="MurG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006009">
        <property type="entry name" value="GlcNAc_MurG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01133">
        <property type="entry name" value="murG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="1 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 10" id="KW-0133">Cell shape</keyword>
    <keyword evidence="9 10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 10 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_28" evidence="11">
        <location>
            <begin position="4"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_tran_28_C" evidence="12">
        <location>
            <begin position="187"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-N-acetyl-alpha-D-glucosamine binding" evidence="10">
        <location>
            <begin position="11"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP44083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY34335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="365" mass="37849" checksum="DB68F7D8991E5FDE" modified="2017-04-12" version="1">MTSVVLAGGGTAGHTSPLIATAKAILARRPDASILCIGTAKGLETRVIPEAGLELRLITPAPLPRSVNLDLVKLPYTLTRSTREARRLLREAKADVLVGFGGYVSIPAYLAARMSGVPVVVHEANKLVGVANKVGARWAHFVGTTFEETTLPGARLIGMPISASITHPKLGAAQARESFGLDPERSTLLVSGGSQGARSINEAVAGAREAILTAGIQILHVLGPKNFGSEHVVVEHDNGARYRPVAFVDDMAVAYAAADLMLGRAGAGTVMETAVSGLPVIFVPWPYGNGEQARNAAGLVAAGAGVMVEDGELTADKLERLVVDLCADPDRLAAMSQAARGMYPSDAAETLAEAVLAAAAKERLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD96</accession>
    <name>A0A1Q2CD96_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl transferase family group 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_03685</name>
        <name evidence="5" type="ORF">SAMN05428934_101339</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY32503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03685"/>
    <dbReference type="EnsemblBacteria" id="AQP44025">
        <property type="protein sequence ID" value="AQP44025"/>
        <property type="gene ID" value="RPIT_03685"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY32503">
        <property type="protein sequence ID" value="SDY32503"/>
        <property type="gene ID" value="SAMN05428934_101339"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03685"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13632">
        <property type="entry name" value="Glyco_trans_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="588"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="631"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="658"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="3">
        <location>
            <begin position="348"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="711"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY32503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="739" mass="80762" checksum="76F4D9902CF3AD68" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDF2</accession>
    <name>A0A1Q2CDF2_9ACTN</name>
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        <submittedName>
            <fullName evidence="6">SPFH domain, Band 7 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_04285</name>
        <name evidence="6" type="ORF">SAMN05428934_101462</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY35950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04285"/>
    <dbReference type="EnsemblBacteria" id="AQP44126">
        <property type="protein sequence ID" value="AQP44126"/>
        <property type="gene ID" value="RPIT_04285"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY35950">
        <property type="protein sequence ID" value="SDY35950"/>
        <property type="gene ID" value="SAMN05428934_101462"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04285"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043202">
        <property type="entry name" value="Band-7_stomatin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_HflKC_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264">
        <property type="entry name" value="PTHR10264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="4">
        <location>
            <begin position="21"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="255"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY35950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="281" mass="30939" checksum="3C7213FEBD0F8C91" modified="2017-04-12" version="1">MPTEIIMGILAVLLLAAFAFASIRVVREYERVVAFRLGRLRGALGPGLVFMLPFLDKLIRIDLRTVTLTIPPQEVITRDNVTARVNAVVMFRVTDPVQAVMSVENHAIATSQFAQTTLRSVVGRADLDTLLAHRADLNEDLAQSIARQTQEWGVEASVVEIKDVEIPEMMQRAMAREAEAERERRAKVISARGELQASKELRDAALTLSEAPASLQLRYLQTLLELGADQNSTVVFPLPMDIVGPIVQAVQRFAGDDDPSSAPPQTHGLKVVDRPLEGESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDU9</accession>
    <name>A0A1Q2CDU9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding transcriptional regulator, PucR family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">PucR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_05215</name>
        <name evidence="5" type="ORF">SAMN05428934_101649</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CdaR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY40682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05215"/>
    <dbReference type="EnsemblBacteria" id="AQP44286">
        <property type="protein sequence ID" value="AQP44286"/>
        <property type="gene ID" value="RPIT_05215"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY40682">
        <property type="protein sequence ID" value="SDY40682"/>
        <property type="gene ID" value="SAMN05428934_101649"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05215"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041522">
        <property type="entry name" value="CdaR_GGDEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025736">
        <property type="entry name" value="PucR_C-HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042070">
        <property type="entry name" value="PucR_C-HTH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17853">
        <property type="entry name" value="GGDEF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13556">
        <property type="entry name" value="HTH_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF_2" evidence="3">
        <location>
            <begin position="173"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_30" evidence="2">
        <location>
            <begin position="330"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY40682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="393" mass="42421" checksum="656C5E81D9603293" modified="2017-04-12" version="1">MDHRPGTAPALISSSRARTALLKRLSAATSEINTATVTAMTQRHEWFGQLDPESRSWIGILARAGIDGFVTWFSGAEFKAETVFEAAPRAMARRISLQQTVDLVRTTTEVLEEQLQHLLPRGDRQPVQLGIVHYSREIAFAAAAIYARAAEARGAWDSRIEATIVDAVVRAETDESMLSRASTLGWNTESRVVVAIGGMAEDGSIDALRRAAAKLSLDVLAAPQGDRLVCIIGGAGVTEPVETCDRIAQLQEHFATGPIVVGPTAETLAGAPRSARAAASGYRAAKAWPEGPRTLLSVDLLPERALAGDGHARRVLASELYPALAAHKELLDTCVGFLDCGSSMEATARALFIHPNTVRYRLKRIQEVTGYNPADPREAYILRMAITLGRLHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDX6</accession>
    <name>A0A1Q2CDX6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">L-lactate permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_05480</name>
        <name evidence="10" type="ORF">SAMN05428934_10343</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Transports L-lactate across the membrane. Can also transport D-lactate and glycolate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the lactate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY66244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05480"/>
    <dbReference type="EnsemblBacteria" id="AQP44332">
        <property type="protein sequence ID" value="AQP44332"/>
        <property type="gene ID" value="RPIT_05480"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY66244">
        <property type="protein sequence ID" value="SDY66244"/>
        <property type="gene ID" value="SAMN05428934_10343"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05480"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015129">
        <property type="term" value="F:lactate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003804">
        <property type="entry name" value="Lactate_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30003">
        <property type="entry name" value="PTHR30003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02652">
        <property type="entry name" value="Lactate_perm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00795">
        <property type="entry name" value="lctP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
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<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44378">
        <property type="protein sequence ID" value="AQP44378"/>
        <property type="gene ID" value="RPIT_05760"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67660">
        <property type="protein sequence ID" value="SDY67660"/>
        <property type="gene ID" value="SAMN05428934_10399"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05760"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY67660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="120" mass="12131" checksum="2AE3C753632B4373" modified="2017-04-12" version="1">MKMRPGERGLSNSVQVAVLLPFSFAVLLAVLQWAMVSWAEATALSAAQHGAAVAAALDGSSAAGEAAATGAARTAALQSVSVTVERGGATTTATVSGRALVVVWPRDVTRTVVVPTERLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE66</accession>
    <name>A0A1Q2CE66_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_05840</name>
        <name evidence="2" type="ORF">SAMN05428934_103115</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44393">
        <property type="protein sequence ID" value="AQP44393"/>
        <property type="gene ID" value="RPIT_05840"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68087">
        <property type="protein sequence ID" value="SDY68087"/>
        <property type="gene ID" value="SAMN05428934_103115"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05840"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY68087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="78" mass="8762" checksum="066AA60CC70661DA" modified="2017-04-12" version="1">MTRAQWATNPLGHTGQWTAADGSKWRTECDTPATGGNGCRTYRWTTVYNAVRSEKGGGYDFTQENKWVVNNIVMFKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE71</accession>
    <name>A0A1Q2CE71_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Small basic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05720</name>
        <name evidence="4" type="ORF">SAMN05428934_10391</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sbp family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05720"/>
    <dbReference type="EnsemblBacteria" id="AQP44370">
        <property type="protein sequence ID" value="AQP44370"/>
        <property type="gene ID" value="RPIT_05720"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67433">
        <property type="protein sequence ID" value="SDY67433"/>
        <property type="gene ID" value="SAMN05428934_10391"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05720"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009709">
        <property type="entry name" value="DUF1290"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06947">
        <property type="entry name" value="DUF1290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018579">
        <property type="entry name" value="Sbp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR018579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY67433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="110" mass="11370" checksum="ADA6D913F9B82B3D" modified="2017-04-12" version="1">MFAVLGLIAGIVVGLIVQPTLPPVLAPYLPIAIVAAFDAILGATRAYLDGIFSDRVFLVSFVSNVLIAGLIVFVGDQIGVGSQLSTGVVVVLGIRIFTNAAAIRRALLHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE90</accession>
    <name>A0A1Q2CE90_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dolichol-phosphate mannosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05985</name>
        <name evidence="3" type="ORF">SAMN05428934_103143</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05985"/>
    <dbReference type="EnsemblBacteria" id="AQP44418">
        <property type="protein sequence ID" value="AQP44418"/>
        <property type="gene ID" value="RPIT_05985"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68802">
        <property type="protein sequence ID" value="SDY68802"/>
        <property type="gene ID" value="SAMN05428934_103143"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05985"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004582">
        <property type="term" value="F:dolichyl-phosphate beta-D-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06442">
        <property type="entry name" value="DPM1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039528">
        <property type="entry name" value="DPM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398">
        <property type="entry name" value="PTHR43398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="15"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY68802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="263" mass="28993" checksum="BFFC545CA9FDFB3E" modified="2017-04-12" version="1">MARMTSQDALDSVLVIIPTYNESQNIESITTRLRRAVPDAHILIADDNSPDGTGEIADRLASDDDHVHVMHRKGKEGLGAAYLAGFHWGLDRGYGVLVSHDADGSHQPEQLPRLLEAIRAGADMVKGSRWVSGGSVVNWPKSRELISRGGSLWTRLWLGIPVKDATGGFNAYRASTLRGISLDEVASAGYCFQIDLVWRALKNGFRVVEVPIEFVEREFGDSKMSRHIVVEALIRTTLWGIEHRLGQLTRLGRRTLTRGDGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CED7</accession>
    <name>A0A1Q2CED7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Indole-3-glycerol phosphate synthase</fullName>
            <shortName evidence="8">IGPS</shortName>
            <ecNumber evidence="8">4.1.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">trpC</name>
        <name evidence="10" type="ORF">RPIT_06440</name>
        <name evidence="11" type="ORF">SAMN05428934_103233</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TrpC family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.48" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06440"/>
    <dbReference type="EnsemblBacteria" id="AQP44492">
        <property type="protein sequence ID" value="AQP44492"/>
        <property type="gene ID" value="RPIT_06440"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71134">
        <property type="protein sequence ID" value="SDY71134"/>
        <property type="gene ID" value="SAMN05428934_103233"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06440"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00043"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004425">
        <property type="term" value="F:indole-3-glycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00331">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00134_A">
        <property type="entry name" value="IGPS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00134_B">
        <property type="entry name" value="IGPS_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045186">
        <property type="entry name" value="Indole-3-glycerol_P_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001468">
        <property type="entry name" value="Indole-3-GlycerolPSynthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22854">
        <property type="entry name" value="PTHR22854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00614">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="IGPS" evidence="9">
        <location>
            <begin position="4"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY71134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="261" mass="27795" checksum="42A800C317B6A8B7" modified="2017-04-12" version="1">MTVLDEIVAGVREDLAEHKSRVPLDDVRRAAREAPPALDPMPRFLADELAVIAEVKRRSPSKGALADIADPAALAASYELGGAAAISVLTEPRRFGGSLADLDAVRAAVQIPVLRKDFMVDEYQFYEARAHGADLVLLIVAALTDDELRRFADLTGELGMTALVETHTPDEVDRALAGGFPLIGVNNRNLKTLDIDLDTFAPLARRLGSGVVRVAESGIFTPQDAARVASEGADAILVGEALVKHGDPVGAIRSFRAASER</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEF4</accession>
    <name>A0A1Q2CEF4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidinol-phosphate aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Imidazole acetol-phosphate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">hisC</name>
        <name evidence="5" type="ORF">RPIT_06375</name>
        <name evidence="6" type="ORF">SAMN05428934_103220</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2-oxoglutarate + L-histidinol phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23744"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="2.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.9" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06375"/>
    <dbReference type="EnsemblBacteria" id="AQP44483">
        <property type="protein sequence ID" value="AQP44483"/>
        <property type="gene ID" value="RPIT_06375"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70796">
        <property type="protein sequence ID" value="SDY70796"/>
        <property type="gene ID" value="SAMN05428934_103220"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06375"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00012"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004400">
        <property type="term" value="F:histidinol-phosphate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01023">
        <property type="entry name" value="HisC_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005861">
        <property type="entry name" value="HisP_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01141">
        <property type="entry name" value="hisC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 3 6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="4">
        <location>
            <begin position="28"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY70796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="362" mass="39132" checksum="92BB468E39419207" modified="2017-04-12" version="1">MITLEELPLRADLVGQEPYGAPQLDVPVVLNVNENPYPPSPAVRREMADAVVAAAGTLNRYPDREALALRSDLAAYLGHGLAAEQIWAANGSNEVMAHLLTAFGGPGRKVLAFTPTYSMYPEYARNTCTEYVTAPRRADFTLDAASVQDAVREHEPTVLIIATPNNPTGTVTDPDVIDEICAGTDAIVVVDEAYQEFADTPSALSLLPRHPRLVVSRTMSKAFALAGGRVGYLAAAPAIVDACRIVRLPYHLSAQTQAVARVALAHADELLAQVRSLAAEARAFEQWARGRGFEVIDSQANFTLFGRFPDRHRVWQALLDRGILIRETGPDGFLRVSAGTPQEMAALRAALDDINPLEASSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEG6</accession>
    <name>A0A1Q2CEG6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Glutamate synthase (NADH) large subunit</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="17">Glutamate synthase large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">RPIT_06420</name>
        <name evidence="18" type="ORF">SAMN05428934_103229</name>
    </gene>
    <organism evidence="17 19">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 19" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">RP1T</strain>
        </source>
    </reference>
    <reference evidence="18 20" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">RP1</strain>
        </source>
    </reference>
    <reference evidence="17" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="14">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glutamate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06420"/>
    <dbReference type="EnsemblBacteria" id="AQP44491">
        <property type="protein sequence ID" value="AQP44491"/>
        <property type="gene ID" value="RPIT_06420"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71027">
        <property type="protein sequence ID" value="SDY71027"/>
        <property type="gene ID" value="SAMN05428934_103229"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06420"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00463"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015930">
        <property type="term" value="F:glutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
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        </source>
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</entry>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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            <dbReference type="PubMed" id="26869509"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
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    </dbReference>
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        <property type="project" value="UniProtKB-EC"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="trehalose_TreZ"/>
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    </dbReference>
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        <location>
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            <end position="456"/>
        </location>
    </feature>
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        <location>
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    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
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            <end position="310"/>
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    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
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            <end position="383"/>
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    </feature>
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        <location>
            <position position="242"/>
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        <location>
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        <source>
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    </evidence>
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        <source>
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        <source>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="PIRNR" id="PIRNR006337"/>
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    </evidence>
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        <source>
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        <source>
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    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP44518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY71937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="564" mass="61442" checksum="FE12658DB41EC58F" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEJ6</accession>
    <name>A0A1Q2CEJ6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane-flanked domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_06600</name>
        <name evidence="4" type="ORF">SAMN05428934_103265</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY72022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06600"/>
    <dbReference type="EnsemblBacteria" id="AQP44521">
        <property type="protein sequence ID" value="AQP44521"/>
        <property type="gene ID" value="RPIT_06600"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY72022">
        <property type="protein sequence ID" value="SDY72022"/>
        <property type="gene ID" value="SAMN05428934_103265"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06600"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005182">
        <property type="entry name" value="DUF304"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03703">
        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="2">
        <location>
            <begin position="84"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY72022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="180" mass="20516" checksum="42A87C4E0A2BC414" modified="2017-04-12" version="1">MGVMGRLLEPQIEAHLLEIEGERVIDEVRKHWAATFWWYCLAGLSLPLFVSMVWARGLFWIPLALGLAALSVGLWKIHVAYMDRFVITNMRVFRVNGVFNTNLATMPMSRILDISMKQPFLGQLCGYGHFVFETAAQDQGLRDITFVGDPQRRDLIIQRVIARAGLRTKMQMDDEDSDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEK9</accession>
    <name>A0A1Q2CEK9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP synthase subunit b</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">ATP synthase F(0) sector subunit b</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">ATPase subunit I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">F-type ATPase subunit b</fullName>
            <shortName evidence="13">F-ATPase subunit b</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">atpF</name>
        <name evidence="16" type="ORF">RPIT_06685</name>
        <name evidence="17" type="ORF">SAMN05428934_110110</name>
    </gene>
    <organism evidence="16 18">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 18" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1T</strain>
        </source>
    </reference>
    <reference evidence="17 19" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">RP1</strain>
        </source>
    </reference>
    <reference evidence="16" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).</text>
    </comment>
    <comment type="function">
        <text evidence="11 13">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12 13">F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cell membrane</location>
            <topology evidence="1 13">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13 14">Belongs to the ATPase B chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ10207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06685"/>
    <dbReference type="EnsemblBacteria" id="AQP44538">
        <property type="protein sequence ID" value="AQP44538"/>
        <property type="gene ID" value="RPIT_06685"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ10207">
        <property type="protein sequence ID" value="SDZ10207"/>
        <property type="gene ID" value="SAMN05428934_110110"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06685"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01398">
        <property type="entry name" value="ATP_synth_b_bprime"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028987">
        <property type="entry name" value="ATP_synth_B-like_membr_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002146">
        <property type="entry name" value="ATP_synth_b/b'su_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005864">
        <property type="entry name" value="ATP_synth_F0_bsu_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00430">
        <property type="entry name" value="ATP-synt_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81573">
        <property type="entry name" value="SSF81573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01144">
        <property type="entry name" value="ATP_synt_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 13 14" id="KW-0138">CF(0)</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 13 14" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 13 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="56"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="AQP44538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="SDZ10207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="180" mass="19831" checksum="EEDC3E78EE9AE9B8" modified="2017-04-12" version="1">MVPTVGVLQETLGPLAPHYWSEVIAGILLMLLIYVIMRKFVVPAFETMYAERANRIEGGMQRAAEAEARAEAALAEYNDQLNAAREEAARIREDAKNQSAMIVAEAREKASKESQRILESGRVQLEAERAQLVSELRGEVGGMATQLAGKIVGESLSDDERAMRTIDRFLAELESAGQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEN4</accession>
    <name>A0A1Q2CEN4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Abasic site processing protein</fullName>
            <ecNumber evidence="7">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_06805</name>
        <name evidence="9" type="ORF">SAMN05428934_11085</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the SOS response-associated peptidase family.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06805"/>
    <dbReference type="EnsemblBacteria" id="AQP44557">
        <property type="protein sequence ID" value="AQP44557"/>
        <property type="gene ID" value="RPIT_06805"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09779">
        <property type="protein sequence ID" value="SDZ09779"/>
        <property type="gene ID" value="SAMN05428934_11085"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06805"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:cellular response to DNA damage stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018142">
        <property type="term" value="P:protein-DNA covalent cross-linking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003738">
        <property type="entry name" value="SRAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036590">
        <property type="entry name" value="SRAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13604">
        <property type="entry name" value="PTHR13604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02586">
        <property type="entry name" value="SRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143081">
        <property type="entry name" value="SSF143081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0190">Covalent protein-DNA linkage</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ09779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="232" mass="25379" checksum="ADA2EF7AAF6F1D96" modified="2017-04-12" version="1">MCGRYAATANPEELAEEFDVEVLADGVSEVAGARFNIAPTDLVPAVVERERGDAVTRSLVPLRWGLVPSWAKAPTTTMINARVETVTEKPAFRKAAAARRCLLPALGYYEWRSEVRPESGPKAIKQPYFLAARDGLLAMAGLYEFWRGPDGWLASTTIITTTATDDLGWVHDRMPMSVPREAWDDWLDPALTDAAHAVTLLRPPALATPYPVSRAVSRVGNDGPQLIDPLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEP1</accession>
    <name>A0A1Q2CEP1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">ATP synthase subunit a</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP synthase F0 sector subunit a</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">F-ATPase subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">atpB</name>
        <name evidence="13" type="ORF">RPIT_06695</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11 12">Cell membrane</location>
            <topology evidence="11 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 12">Belongs to the ATPase A chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06695"/>
    <dbReference type="EnsemblBacteria" id="AQP44540">
        <property type="protein sequence ID" value="AQP44540"/>
        <property type="gene ID" value="RPIT_06695"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06695"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01393">
        <property type="entry name" value="ATP_synth_a_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000568">
        <property type="entry name" value="ATP_synth_F0_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023011">
        <property type="entry name" value="ATP_synth_F0_asu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045083">
        <property type="entry name" value="ATP_synth_F0_asu_bact/mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035908">
        <property type="entry name" value="F0_ATP_A_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11410">
        <property type="entry name" value="PTHR11410"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00119">
        <property type="entry name" value="ATP-synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00123">
        <property type="entry name" value="ATPASEA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81336">
        <property type="entry name" value="SSF81336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01131">
        <property type="entry name" value="ATP_synt_6_or_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00449">
        <property type="entry name" value="ATPASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 11 12" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 11 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 11 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="88"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="184"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP44540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="259" mass="29008" checksum="DFDCC064332C672E" modified="2017-04-12" version="1">METGGGYEPPGTKDFLWDSIWPGVLPDWVNKPLLQAIIGALLVIALWWVASRNLKIKPGKGQFLAEYVYEFIRNGIARDILHSDFRKFLPYLLGLFSFLLVNNWFGQFFFFMYPTFSNVGYAYGLAILSWLVYVGAGFKKWGFGGFLKKSLVPDGVPFYLLPLVVPLEFLATFITRPITLALRLFANLFAGHLVVVVFVVGGGWLLTQQDNLFYNVSGGVSMAFSLIILCLELFIGALQAYIFTVLTAQYVSTSIAEAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CER6</accession>
    <name>A0A1Q2CER6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Release factor glutamine methyltransferase</fullName>
            <shortName evidence="5">RF MTase</shortName>
            <ecNumber evidence="5">2.1.1.297</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">N5-glutamine methyltransferase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Protein-(glutamine-N5) MTase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Protein-glutamine N-methyltransferase PrmC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">prmC</name>
        <name evidence="8" type="ORF">RPIT_06720</name>
        <name evidence="9" type="ORF">SAMN05428934_110103</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine = H(+) + N(5)-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42896"/>
            <dbReference type="Rhea" id="RHEA-COMP:10271"/>
            <dbReference type="Rhea" id="RHEA-COMP:10272"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
            <dbReference type="EC" id="2.1.1.297"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.297" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ10078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06720"/>
    <dbReference type="EnsemblBacteria" id="AQP44545">
        <property type="protein sequence ID" value="AQP44545"/>
        <property type="gene ID" value="RPIT_06720"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ10078">
        <property type="protein sequence ID" value="SDZ10078"/>
        <property type="gene ID" value="SAMN05428934_110103"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06720"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102559">
        <property type="term" value="F:protein-(glutamine-N5) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036009">
        <property type="term" value="F:protein-glutamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018364">
        <property type="term" value="P:peptidyl-glutamine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02126">
        <property type="entry name" value="RF_methyltr_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004556">
        <property type="entry name" value="HemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040758">
        <property type="entry name" value="PrmC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019874">
        <property type="entry name" value="Release_fac_Glu-N5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17827">
        <property type="entry name" value="PrmC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00536">
        <property type="entry name" value="hemK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03534">
        <property type="entry name" value="RF_mod_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PrmC_N" evidence="7">
        <location>
            <begin position="3"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransf_25" evidence="6">
        <location>
            <begin position="114"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="183"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ10078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="279" mass="30123" checksum="C535DCB77D7AF626" modified="2017-04-12" version="1">MTELVHEIAGLLGRSGVASPAPEARTLVAHVLGVEPRDLLRVRGVSDEQRAMIDALAARRAAGEPLQHITGLAYFRYETLSVGPGVFIPRPETEEMVGWALSELARRPVGARRVVELCAGSGAITAALARELGGLDLYAVELSADAFGYLERNLEAVDVHLVLGDMASAFPELDGTVDLVIANPPYIPEAHRVILPDDVVLHDPHLALFSGADGLDALRVVAETSSRLLKPGGLVAAEHDESHAEDVVRLFADGFHDVTSRRDLTRRPRYVTAVRSWQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CES4</accession>
    <name>A0A1Q2CES4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcriptional repressor NrdR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nrdR</name>
        <name evidence="11" type="ORF">RPIT_07025</name>
        <name evidence="12" type="ORF">SAMN05428934_11040</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NrdR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07025"/>
    <dbReference type="EnsemblBacteria" id="AQP44597">
        <property type="protein sequence ID" value="AQP44597"/>
        <property type="gene ID" value="RPIT_07025"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08833">
        <property type="protein sequence ID" value="SDZ08833"/>
        <property type="gene ID" value="SAMN05428934_11040"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07025"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00440">
        <property type="entry name" value="NrdR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003796">
        <property type="entry name" value="RNR_NrdR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30455">
        <property type="entry name" value="PTHR30455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00244">
        <property type="entry name" value="TIGR00244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0678">Repressor</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ATP-cone" evidence="10">
        <location>
            <begin position="46"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="zinc finger region" evidence="7">
        <location>
            <begin position="3"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDZ08833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="171" mass="18641" checksum="AD1F68CD953D2F45" modified="2017-04-12" version="1">MHCPFCRHGDTKVSDSRATEDGSAIRRRRLCPVCERKFTTVEQIVLTVVKRSGVVEAFSRDKVVRGVSKACKGRPVTAAQLAALAQRVEESLRASGQAEIPAESIGVAILGPLEELDSVAYLRFASVYKNYDSVDDFQKEIDALRLSAAERMAAPHGLKMPVGSAQEPLIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEX1</accession>
    <name>A0A1Q2CEX1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07400</name>
        <name evidence="2" type="ORF">SAMN05428934_11437</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000014">
        <property type="protein sequence ID" value="SDZ18520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07400"/>
    <dbReference type="EnsemblBacteria" id="AQP44656">
        <property type="protein sequence ID" value="AQP44656"/>
        <property type="gene ID" value="RPIT_07400"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ18520">
        <property type="protein sequence ID" value="SDZ18520"/>
        <property type="gene ID" value="SAMN05428934_11437"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07400"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ18520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="92" mass="9530" checksum="270F175FEFE2F33F" modified="2017-04-12" version="1">MQPAGLYVDHGDVLTSAGTASAIDACLHIVRSQLGSAAAATVARSLVVAPHRDGDQAHLDHELTVDDLAAHARMSRRNCTHRFAAATGTTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF19</accession>
    <name>A0A1Q2CF19_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07710</name>
        <name evidence="3" type="ORF">SAMN05428934_1186</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000018">
        <property type="protein sequence ID" value="SDZ21336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44706">
        <property type="protein sequence ID" value="AQP44706"/>
        <property type="gene ID" value="RPIT_07710"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ21336">
        <property type="protein sequence ID" value="SDZ21336"/>
        <property type="gene ID" value="SAMN05428934_1186"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07710"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="94"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ21336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="227" mass="24362" checksum="B7E1F062659F174A" modified="2017-04-12" version="1">MHLSQHLQPITETEAVALASCWGVSAQDVIDTRRSSWVQATSPGDATGPRLVQFRDRTLAVYPHPGEPNQAWAPRFLAVRAFADTATAPMPERATARLHSTDAPLVVDLHERCSRADLAAATPHLGQETILARGVIIDHRLVAMCTLVPTCAGPPEVSVLACPSSRGRGYATAAERAVLVDAARHGIGTVQHRTIAQDHASISLALRSGFRILTLEHIVQPASTTDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF33</accession>
    <name>A0A1Q2CF33_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07745</name>
        <name evidence="3" type="ORF">SAMN05428934_11814</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000018">
        <property type="protein sequence ID" value="SDZ21476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07745"/>
    <dbReference type="EnsemblBacteria" id="AQP44711">
        <property type="protein sequence ID" value="AQP44711"/>
        <property type="gene ID" value="RPIT_07745"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ21476">
        <property type="protein sequence ID" value="SDZ21476"/>
        <property type="gene ID" value="SAMN05428934_11814"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07745"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ21476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="317" mass="34607" checksum="E8071B0C0B5B0BE7" modified="2017-04-12" version="1">MTAFEASSANRAYVQWLEEQSMLHDARQVSRQVAGSHTMWANAYAHPDPRAAGHAIQDVAGNTLGRSFAADGTVLSGHGGIPGTPVRDIPGIGIPSNHMVVPEGVRIRMYGAEGDTILDSLGNQIERQMRWPFCPPDRGCLRARGRHPRARALPAHAGPGHHQQPRHGVHRDVPGRPDHPQRRHLRLGGVPQLPPCCPERSPMCHEDGSVLSPRKWPWQKDTLAFGWLDPRRPFREGPCPSEVRRGLIDKAIPPVWPDGTPAPIDTAFAIKVPAGTEIHTGTVANQGGLWMGGTEQVVVVKPWEIGGVEVGYSWPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF69</accession>
    <name>A0A1Q2CF69_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease VapC</fullName>
            <shortName evidence="6">RNase VapC</shortName>
            <ecNumber evidence="6">3.1.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Toxin VapC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">vapC</name>
        <name evidence="8" type="ORF">RPIT_07645</name>
        <name evidence="9" type="ORF">SAMN05428934_12110</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Toxic component of a toxin-antitoxin (TA) system. An RNase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PINc/VapC protein family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000021">
        <property type="protein sequence ID" value="SDZ22762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07645"/>
    <dbReference type="EnsemblBacteria" id="AQP44695">
        <property type="protein sequence ID" value="AQP44695"/>
        <property type="gene ID" value="RPIT_07645"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ22762">
        <property type="protein sequence ID" value="SDZ22762"/>
        <property type="gene ID" value="SAMN05428934_12110"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07645"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09873">
        <property type="entry name" value="PIN_Pae0151-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00265">
        <property type="entry name" value="VapC_Nob1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044153">
        <property type="entry name" value="PIN_Pae0151-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022907">
        <property type="entry name" value="VapC_family"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0800">Toxin</keyword>
    <keyword evidence="1 6" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="domain" description="PINc" evidence="7">
        <location>
            <begin position="3"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="5"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ22762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="133" mass="14872" checksum="DCABBCAD102543C6" modified="2017-04-12" version="1">MLVIDASVLAVALLDDGRDGDAVRDRLRGEQLAAPALIDLEVASVWRGLARGGHLDPRRVRLALDDLQELPLQRVEHTSLLWRCWELRDNLTIYDAAYVALAEALQAPLLTGERRLARSTGPRCTIEVMKTHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFA9</accession>
    <name>A0A1Q2CFA9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_08400</name>
        <name evidence="2" type="ORF">SAMN05428934_1204</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000020">
        <property type="protein sequence ID" value="SDZ22196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44812">
        <property type="protein sequence ID" value="AQP44812"/>
        <property type="gene ID" value="RPIT_08400"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ22196">
        <property type="protein sequence ID" value="SDZ22196"/>
        <property type="gene ID" value="SAMN05428934_1204"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08400"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ22196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="110" mass="12399" checksum="1B93E20865EB61E7" modified="2017-04-12" version="1">MIKDSADRSPLFENAQATDLTRFIVFDPDMDERAVAAGYEEAAKRLASSVTGKPVDDLILMPLLFLWRQAIELILKATIRDLCKIRRARGENQDELKTEKVAVRAPPQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFC3</accession>
    <name>A0A1Q2CFC3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Diadenosine tetraphosphate (Ap4A) hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">HIT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_08420</name>
        <name evidence="4" type="ORF">SAMN05428934_1208</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000020">
        <property type="protein sequence ID" value="SDZ22260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44816">
        <property type="protein sequence ID" value="AQP44816"/>
        <property type="gene ID" value="RPIT_08420"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ22260">
        <property type="protein sequence ID" value="SDZ22260"/>
        <property type="gene ID" value="SAMN05428934_1208"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08420"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY59858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44992">
        <property type="protein sequence ID" value="AQP44992"/>
        <property type="gene ID" value="RPIT_09510"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59858">
        <property type="protein sequence ID" value="SDY59858"/>
        <property type="gene ID" value="SAMN05428934_102404"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09510"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018561">
        <property type="entry name" value="DUF2017"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09438">
        <property type="entry name" value="DUF2017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2017" evidence="1">
        <location>
            <begin position="39"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY59858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="196" mass="21868" checksum="E1FF1219DF71CFBC" modified="2017-04-12" version="1">MTLDPEDIVWAFDGSEGRGEGLSAMIGIYTMHLTTLLPDASDDPFEQIVADLADDPTNRMLGNPRLGRLYPPALEDSKGADEFWKDSIHSLTRSRLEAAETVRRSLDDWDGPVPVTLGAVDSWAKTLGGMRLFWYSELAGTDRMADVVVTEENESLVDLVEWLGYLLEDLMESRETCLNLVASLDPDQFQPSERDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFX8</accession>
    <name>A0A1Q2CFX8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09670</name>
        <name evidence="3" type="ORF">SAMN05428934_102371</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY58977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45021">
        <property type="protein sequence ID" value="AQP45021"/>
        <property type="gene ID" value="RPIT_09670"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY58977">
        <property type="protein sequence ID" value="SDY58977"/>
        <property type="gene ID" value="SAMN05428934_102371"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09670"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544469" evidence="1">
        <location>
            <begin position="33"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY58977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="139" mass="14435" checksum="B17338D958D0E169" modified="2017-04-12" version="1">MLTRILAAIAAALVLAGCSAEPLPSPPTSPDASESVPLAVPADGVRLRDLGFLHAPSGFTVPEGLTIIERVDAANNVTAVVRTSDGGRIADYLRQHLPAMGFTITADRDLSLRFTDGTHDGAFTVTGDLAALSLRTDRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFY1</accession>
    <name>A0A1Q2CFY1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_09585</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09585"/>
    <dbReference type="EnsemblBacteria" id="AQP45007">
        <property type="protein sequence ID" value="AQP45007"/>
        <property type="gene ID" value="RPIT_09585"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09585"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010428">
        <property type="entry name" value="Zincin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038555">
        <property type="entry name" value="Zincin_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06262">
        <property type="entry name" value="Zincin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="145" mass="16049" checksum="79524470DE453393" modified="2017-04-12" version="1">MPRRRDRHGRGIRGPLAAPNPLLGRPVPLFRPGRVDFFNDCVTSAMADIASIAPGALNGIVVGVEDVPQLNLTWSGDRVPLSAALEPSRGRRAQIVIYQRPLEHRASSRGELRRLVHRTIVEQLSTLTGRSIDELVGEDPDWDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG12</accession>
    <name>A0A1Q2CG12_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="6">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_09880</name>
        <name evidence="11" type="ORF">SAMN05428934_102330</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY57751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09880"/>
    <dbReference type="EnsemblBacteria" id="AQP45058">
        <property type="protein sequence ID" value="AQP45058"/>
        <property type="gene ID" value="RPIT_09880"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57751">
        <property type="protein sequence ID" value="SDY57751"/>
        <property type="gene ID" value="SAMN05428934_102330"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09880"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005751">
        <property type="entry name" value="ATP-dep_DNA_helicase_PcrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01073">
        <property type="entry name" value="pcrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="8">
        <location>
            <begin position="43"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="9">
        <location>
            <begin position="336"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="64"/>
            <end position="71"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP45058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY57751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="805" mass="88528" checksum="62B271F0A8BF6DB1" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG34</accession>
    <name>A0A1Q2CG34_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">5-oxoprolinase subunit A</fullName>
            <shortName evidence="1">5-OPase subunit A</shortName>
            <ecNumber evidence="1">3.5.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">5-oxoprolinase (ATP-hydrolyzing) subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pxpA</name>
        <name evidence="2" type="ORF">RPIT_09995</name>
        <name evidence="3" type="ORF">SAMN05428934_102307</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-oxo-L-proline + ATP + 2 H2O = ADP + H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10348"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58402"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.5.2.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms a complex composed of PxpA, PxpB and PxpC.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LamB/PxpA family.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.9" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY57107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09995"/>
    <dbReference type="EnsemblBacteria" id="AQP45079">
        <property type="protein sequence ID" value="AQP45079"/>
        <property type="gene ID" value="RPIT_09995"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57107">
        <property type="protein sequence ID" value="SDY57107"/>
        <property type="gene ID" value="SAMN05428934_102307"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09995"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017168">
        <property type="term" value="F:5-oxoprolinase (ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00691">
        <property type="entry name" value="PxpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005501">
        <property type="entry name" value="LamB/YcsF/PxpA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30292">
        <property type="entry name" value="PTHR30292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03746">
        <property type="entry name" value="LamB_YcsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY57107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="248" mass="25953" checksum="C7D6934F44F3A2EF" modified="2017-04-12" version="1">MDLNADLGESFGVWRLGDDAAMLGIVSSANVACGFHAGDPLTLLGTCEEAARSGVVVGAQVSYRDLAGFGRRFVDAGRAELAADLVYQIGALDGLCRSSGTRVRYVKPHGALYNAAVHHEPHADAVVDAVLAYDPSLPILGLPGSLLLRKAEKAGLRTVAEAFADRAYRPDGTLVPRTDAGAIVHDDVGQRMLRLAHEGLLEAVDGTLIPLRAESICTHGDTPGAVGLARAVRRALEGAGIEIAPFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG36</accession>
    <name>A0A1Q2CG36_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Maltose O-acetyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Maltose acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_09980</name>
        <name evidence="6" type="ORF">SAMN05428934_102310</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY57180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09980"/>
    <dbReference type="EnsemblBacteria" id="AQP45076">
        <property type="protein sequence ID" value="AQP45076"/>
        <property type="gene ID" value="RPIT_09980"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57180">
        <property type="protein sequence ID" value="SDY57180"/>
        <property type="gene ID" value="SAMN05428934_102310"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09980"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024688">
        <property type="entry name" value="Mac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12464">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01266">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Mac" evidence="4">
        <location>
            <begin position="12"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY57180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="198" mass="21608" checksum="FE50DC4C18AE601C" modified="2017-04-12" version="1">MDYFTDDPRSNWQRLLVGDLYIADDPTMAERSTRATRLSDEYHRAYVKGREDAGEILAELLGSMGRDVWVRPPLYVDYGEFIHIGDGTQINFNLTALDVAPITIGRDCLIGPNVQLLTAWHPIEPQPRRDKLESASPITLQDNVWLGGGVIVLPGVTIGENSIVGAGAVVTSDIPADSIAVGNPARVIRSVTEGDAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGC0</accession>
    <name>A0A1Q2CGC0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Ribosomal protein S18 acetylase RimI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10400</name>
        <name evidence="3" type="ORF">SAMN05428934_102225</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY54904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45153">
        <property type="protein sequence ID" value="AQP45153"/>
        <property type="gene ID" value="RPIT_10400"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY54904">
        <property type="protein sequence ID" value="SDY54904"/>
        <property type="gene ID" value="SAMN05428934_102225"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10400"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="18"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY54904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="176" mass="19624" checksum="93EBEA0FEB5D27B8" modified="2017-04-12" version="1">MALTFRRADATDTAVAQEAYRLIIDHLAETVDFPHWHTENHPTPEEVASWVEAGELYLALDEDGETAGVTVLNHDAVDAYHEAAWTVEAEPHEVLVVHALGVVPERLGTGVSQFLVDASLQVAREQGCKAVRLDTYVENTPARKLYERHGFIDLGCHNVVYEGTDLSQFHLFEYAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGD0</accession>
    <name>A0A1Q2CGD0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator receiver domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_10450</name>
        <name evidence="5" type="ORF">SAMN05428934_102215</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="de Groot N.N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 7">RP1</strain>
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                <person name="Peterson S.W."/>
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        </source>
    </reference>
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        <property type="gene ID" value="SAMN05428934_102215"/>
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    <evidence type="ECO:0000313" key="7">
        <source>
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    </evidence>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
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    </evidence>
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        <source>
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</entry>
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    <accession>A0A1Q2CGX9</accession>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3" key="3">
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
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        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45305">
        <property type="protein sequence ID" value="AQP45305"/>
        <property type="gene ID" value="RPIT_11285"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY49450">
        <property type="protein sequence ID" value="SDY49450"/>
        <property type="gene ID" value="SAMN05428934_10246"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11285"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY49450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="64" mass="6985" checksum="701E79C423834A6D" modified="2017-04-12" version="1">MWSHDRSASERVRRGARKLGPYIVVAAVLLALVVGMMVFFLLRQDDGGRACPPTAGLGVVVVRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH27</accession>
    <name>A0A1Q2CH27_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11900</name>
        <name evidence="3" type="ORF">SAMN05428934_10695</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45414">
        <property type="protein sequence ID" value="AQP45414"/>
        <property type="gene ID" value="RPIT_11900"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92779">
        <property type="protein sequence ID" value="SDY92779"/>
        <property type="gene ID" value="SAMN05428934_10695"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11900"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY92779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="168" mass="18623" checksum="0E5E085A5BD14FFB" modified="2017-04-12" version="1">MTDYNTDKPQGEGMYEDAVHDAEFVQPDEQPRHEDVDKSESHRPNPDQLGENFKKLANEAAYAAVGFAGLVGEKAKEFYEDQKRQYAETHPDADHDPGAKDFLAQLREKIDKFVDELTKGYKDMADRGRAKADRPADGSAPSGDPVDVPSQHAEADASVDPEATNYPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH69</accession>
    <name>A0A1Q2CH69_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Thiamine-phosphate synthase</fullName>
            <shortName evidence="9">TP synthase</shortName>
            <shortName evidence="9">TPS</shortName>
            <ecNumber evidence="9">2.5.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Thiamine-phosphate pyrophosphorylase</fullName>
            <shortName evidence="9">TMP pyrophosphorylase</shortName>
            <shortName evidence="9">TMP-PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">thiE</name>
        <name evidence="13" type="ORF">RPIT_11840</name>
        <name evidence="14" type="ORF">SAMN05428934_106106</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 9">Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9 10">
            <text>2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47848"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62890"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 9 10">
            <text>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47844"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 9 10">
            <text>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 4-methyl-5-(2-phosphooxyethyl)-thiazole + H(+) = diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:22328"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 9 11">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the thiamine-phosphate synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.3" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11840"/>
    <dbReference type="EnsemblBacteria" id="AQP45405">
        <property type="protein sequence ID" value="AQP45405"/>
        <property type="gene ID" value="RPIT_11840"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93018">
        <property type="protein sequence ID" value="SDY93018"/>
        <property type="gene ID" value="SAMN05428934_106106"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11840"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00141"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004789">
        <property type="term" value="F:thiamine-phosphate diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00564">
        <property type="entry name" value="TMP_TenI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00097">
        <property type="entry name" value="TMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036206">
        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034291">
        <property type="entry name" value="TMP_synthase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="SSF51391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00693">
        <property type="entry name" value="thiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9 10" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="6 9 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TMP-TENI" evidence="12">
        <location>
            <begin position="15"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="HMP-PP binding" evidence="9">
        <location>
            <begin position="46"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="THZ-P binding" evidence="9">
        <location>
            <begin position="149"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="THZ-P binding" evidence="9">
        <location>
            <begin position="202"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP45405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY93018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="225" mass="23410" checksum="4C492EFE07853D3B" modified="2017-04-12" version="1">MQARPGLADAVDWRLYYVTDTALSGGPDEVPGFVEAAVAGGAGVVQIRDKELPDDAYRELVVRCVAANERAHDATGRRAAIVVNDRLSVAADLGLHFHQGQDDGDVRRARRVLGEGLLIGLSISDDEQLAAELADPTADALGLSPVWATPTKEDTAPALGLDGVARLTLAARGAAKTLAIGGINLVNAGSVIETGVDGLCVVSAITSSPDPRHAAEQLLALWSHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH72</accession>
    <name>A0A1Q2CH72_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha-1,6-mannosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12120</name>
        <name evidence="3" type="ORF">SAMN05428934_10652</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY91795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12120"/>
    <dbReference type="EnsemblBacteria" id="AQP45457">
        <property type="protein sequence ID" value="AQP45457"/>
        <property type="gene ID" value="RPIT_12120"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY91795">
        <property type="protein sequence ID" value="SDY91795"/>
        <property type="gene ID" value="SAMN05428934_10652"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12120"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="279"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="342"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="439"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY91795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="466" mass="50540" checksum="6E1E50772ADAB30F" modified="2017-04-12" version="1">MRVPSVRSAPSGPTAPWLWVAVGLCAVALLVGVLAADADGLLETPASWWRPVATLPLHAVLLLAWWQLGPRWRRPLVTAALWSLPMLFALPMHSRDAYAYGAAGWLVNQGRDPYTTPIGQAGEPGLLVGVHWHETTSVYPGLSLDLFGWLSRLTDADLYWTTVALRLPNVAALVILALVLPRLARRFGVDERLVLWAGLLNPIMLVQWVGGVHNDALMVALGVAAFLAVTDLGWRGWRGLVVAGVLLGLAMGIKQSAALFGLGVVAVAWSLRYPRVAGWWRLAAVAVVPGSVTVATFVLTSLGHGFGWSNDTAGSPIEATSNAPLSWLASFLRYREIVSEEVANGSVGLLSTMLIIVGVILAWVKFGPKGDARGRPWVFAAAVVAVFCLAAPALQPWYLTWLLPLYPFVRVGPRWHRWWQVAVAAFALLPALQDLLPPYVSMLIVGVPLLLLWRLMVRRDVSPLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHA9</accession>
    <name>A0A1Q2CHA9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_12085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12085"/>
    <dbReference type="EnsemblBacteria" id="AQP45450">
        <property type="protein sequence ID" value="AQP45450"/>
        <property type="gene ID" value="RPIT_12085"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12085"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="8"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="398" mass="42583" checksum="2EBE7EF9E7AB4F49" modified="2017-04-12" version="1">MAGTGQGQLVLLFDESLSLKESDPDAGRVLAGRYLVQRLANLADRSELDLQVMLAGFGTSYRDYQSQWRTLAGADLNGLLTDLESFADRNTDSGTDYWLGLDGARKSLADVRLTDGAGCQAIFFFSDGELDVSLSADERAEGEANPRRPFAPDNDMSTRERELAATAAAAESLCRAGGLADQIRLQDIVMFGVGLHGDDQSADAFDLMRRVVTGGRGQGTCGAQTQPVPGDFVTAADIDSLIFAFDSVTRQRPVNETEICQGDVCLAGTHNFVLDASVERVELLGSADADGIEVQLTAPGGAQGDSSGETSRNHRRSIFQGREANTPGSVIAPSWSRSKQRTPSNGLDSGRLLSSTQTLPLRERRLAPASTLQATLLRDSWSKTSLFAQGTPTHFGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHB1</accession>
    <name>A0A1Q2CHB1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional attenuator, LytR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_12365</name>
        <name evidence="6" type="ORF">SAMN05428934_1063</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LytR/CpsA/Psr (LCP) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY90717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12365"/>
    <dbReference type="EnsemblBacteria" id="AQP45497">
        <property type="protein sequence ID" value="AQP45497"/>
        <property type="gene ID" value="RPIT_12365"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY90717">
        <property type="protein sequence ID" value="SDY90717"/>
        <property type="gene ID" value="SAMN05428934_1063"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12365"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004474">
        <property type="entry name" value="LytR_CpsA_psr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03816">
        <property type="entry name" value="LytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00350">
        <property type="entry name" value="lytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="LytR_cpsA_psr" evidence="4">
        <location>
            <begin position="110"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="67"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY90717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="356" mass="38812" checksum="ADA6049D8DF78446" modified="2017-04-12" version="1">MGRAIDDGLEVFEDDDYQAEPRRRRGPGFVLLMLSVGVLVIALGVVGFYAARGLLALNSIDRDESLTPTDYTGRPALTKPKAPVGDEEPGKPPVNFVLMGADTTEGDAGRSDSLMVAHVTGDRQAVYLISFPRDMWVEIPGRGEGKINWAYAFGGPQLTVRTLEQMTGVRMDHTVSIDFDGFMRLTDAVGGVTVYNPWDSNQFAKGEVDLQGERALAYVRERYDLPNGDLDRAFRQRTVVKAIIRKLLTPETIANPVTFSNVIGQVADTMTVDDQMTNRYVTELALSMRITSGESIGLMQAPIEGFATIGGQAVDVVDWDGVAELSGALSGDTMDEYYAKHGNAQQIELGQVEPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHB7</accession>
    <name>A0A1Q2CHB7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_12135</name>
        <name evidence="8" type="ORF">SAMN05428934_10649</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY91736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12135"/>
    <dbReference type="EnsemblBacteria" id="AQP45460">
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        <property type="gene ID" value="RPIT_12135"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY91736"/>
        <property type="gene ID" value="SAMN05428934_10649"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12135"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="147"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY91736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="168" mass="17899" checksum="33854A50807375E2" modified="2017-04-12" version="1">MAPFLRFIRDFALLVTRIIVGVTLVAHGWHRWQVTGLEEQMDIIAEVGLPSAYGLAVATVAFEIIGGILLIFGLATPLVGLGMLVLNAAIILTTKADSGFYAHENGWEYNAVQAGVGLILLAFGSGRAGLDHLFIRPRDEDGVLISPAPPPRQPPPAAADDDTQPPHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHD1</accession>
    <name>A0A1Q2CHD1_9ACTN</name>
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        <submittedName>
            <fullName evidence="4">Membrane protein YdbS, contains bPH2 (Pleckstrin homology) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_12480</name>
        <name evidence="4" type="ORF">SAMN05428934_104190</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY80300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12480"/>
    <dbReference type="EnsemblBacteria" id="AQP45517">
        <property type="protein sequence ID" value="AQP45517"/>
        <property type="gene ID" value="RPIT_12480"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY80300">
        <property type="protein sequence ID" value="SDY80300"/>
        <property type="gene ID" value="SAMN05428934_104190"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="DUF304"/>
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    </dbReference>
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    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="2">
        <location>
            <begin position="73"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY80300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="158" mass="17334" checksum="BC46DB7F872136A4" modified="2017-04-12" version="1">MNETQTGDGVKRLPEAARTYRMIQAVTVAGILTAVACAAVVLLRLPVPLPFVVAVGALFLTVDLVFIPLRHHWFRYRVSEDEYFVSRGRFLLTTVTVAVPQILHAEVIQGPVLRQFGLATVRVKMVVGDHELGPVTTQEADAIRRTILSGSGRTVDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHH4</accession>
    <name>A0A1Q2CHH4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-dependent succinic semialdehyde dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_12765</name>
        <name evidence="5" type="ORF">SAMN05428934_104134</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY78704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12765"/>
    <dbReference type="EnsemblBacteria" id="AQP45569">
        <property type="protein sequence ID" value="AQP45569"/>
        <property type="gene ID" value="RPIT_12765"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY78704">
        <property type="protein sequence ID" value="SDY78704"/>
        <property type="gene ID" value="SAMN05428934_104134"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12765"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004030">
        <property type="term" value="F:aldehyde dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07100">
        <property type="entry name" value="ALDH_SSADH1_GabD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
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        <property type="entry name" value="ALDH_GabD1-like"/>
    </dbReference>
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        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="3"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY78704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="458" mass="49483" checksum="3B69E92E46D44E04" modified="2017-04-12" version="1">MAITSINPATGELLREFPPHSPEDVRDRIEQAQRAFLKMKDTDFETRAAWMRKAADLMEADVDELGKTLTLEMGKTFEQARAEILKSAKVMRFYADRAAEFLAPEELDDPSSVGAKKAYTVYEPMGVILAVMPWNYPIWQVVRFAAPTLMAGNAALLKHASNVPQAALYLDEIFLRGGFPEGAFRSLLISSSAVEGVIRDRRVAAVTLTGSEPAGRSVAAIAGSEVKHSVLELGGSDPFIVMPTADLDEAASMAVKSRTINNGQACINAKRFIVHADVYDEFMERFNRQMADLKVGDPMNPGTDIGPLATSSGREDLIELVEDARSKGADIPVGGTVPDGPGWFYPPTVVTGVTPDMRLYAEEAFGPVAAVLQAADAAEAVRIANDTTFGLSSAVWTNSDDDVEFFTRSLDAGAVFVNGMSVSYPELPFGGVKDSGIGRELSAEGIRAFCNVKSVWRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHI3</accession>
    <name>A0A1Q2CHI3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Quinolinate synthase</fullName>
            <ecNumber evidence="3">2.5.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_12785</name>
        <name evidence="11" type="ORF">SAMN05428934_104130</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from iminoaspartate: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.72" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY78580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12785"/>
    <dbReference type="EnsemblBacteria" id="AQP45572">
        <property type="protein sequence ID" value="AQP45572"/>
        <property type="gene ID" value="RPIT_12785"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY78580">
        <property type="protein sequence ID" value="SDY78580"/>
        <property type="gene ID" value="SAMN05428934_104130"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12785"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00327"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008987">
        <property type="term" value="F:quinolinate synthetase A activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
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</entry>
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</entry>
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            <authorList>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 10">RP1T</strain>
        </source>
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            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
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    </dbReference>
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    </evidence>
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            <dbReference type="Proteomes" id="UP000188324"/>
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            <dbReference type="Proteomes" id="UP000199635"/>
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</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHQ9</accession>
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        <submittedName>
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
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</entry>
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</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY75763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13295"/>
    <dbReference type="EnsemblBacteria" id="AQP45665">
        <property type="protein sequence ID" value="AQP45665"/>
        <property type="gene ID" value="RPIT_13295"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY75763">
        <property type="protein sequence ID" value="SDY75763"/>
        <property type="gene ID" value="SAMN05428934_10428"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13295"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002028">
        <property type="entry name" value="Trp_synthase_suA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43406">
        <property type="entry name" value="PTHR43406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00290">
        <property type="entry name" value="Trp_syntA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0822">Tryptophan biosynthesis</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY75763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="272" mass="28814" checksum="4D428166D6208736" modified="2017-04-12" version="1">MPSRLRRRFAQSKAERRGVLFGYLPAGYPTPDDFLASAAAAFDAGLDALEVGLPSPVPDLDGPLIKAAIAEGSRHVPTVRDALQLAASARRDDDDSIIALAYGSLFERVSVDDFLQLVKDADVDAVLLPQASVADQLDISRRAARLGIDVVVFLHLEEDLPVLVATSDDPIIYLQSAALRTGGQFNPDKAQERLRELAEAFDGRPYSVCVGFGVRGREDVAALMAGGADGAIIGTRLVAAAGERPADVGAIVDEVAPVLVRRAELGEHPDAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI21</accession>
    <name>A0A1Q2CI21_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_13535</name>
        <name evidence="7" type="ORF">SAMN05428934_11192</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ13244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13535"/>
    <dbReference type="EnsemblBacteria" id="AQP45705">
        <property type="protein sequence ID" value="AQP45705"/>
        <property type="gene ID" value="RPIT_13535"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ13244">
        <property type="protein sequence ID" value="SDZ13244"/>
        <property type="gene ID" value="SAMN05428934_11192"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13535"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="4">
        <location>
            <begin position="31"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ13244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="105" mass="11416" checksum="F282913D9A0ED559" modified="2017-04-12" version="1">MPVTAVTEKTFVDEVLMGEGLVIVDYWADWCAPCKQMSPIIDELAKEYPDVKFVKVDTNANPNLAAEQGVLSLPTLQFFTGGRVAKSLSGGKTKGALKKAIDELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI42</accession>
    <name>A0A1Q2CI42_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_13910</name>
        <name evidence="2" type="ORF">SAMN05428934_11118</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ11917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45764">
        <property type="protein sequence ID" value="AQP45764"/>
        <property type="gene ID" value="RPIT_13910"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ11917">
        <property type="protein sequence ID" value="SDZ11917"/>
        <property type="gene ID" value="SAMN05428934_11118"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13910"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ11917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="253" mass="28221" checksum="09E2E6A145782F84" modified="2017-04-12" version="1">MVGLLGEELGTPENADALVTAWAKLFRRQVVVGSGARFVDLALIGTSEDALFNLQFLTHAFKACYVNRFLYHYRRDNATSVTTRYKPELPHQWSRLPEVMKQHIAHHSLGPDFEQALRNRVSLSVLGLGLNALQSGLAPQHVIRDIRLASMMTNDPKDRHVLAAAVRGGAEVLVTFNTRHSSLESVERFDLEVVHLDDFLLDQLDLYHAPTLRALVELVEGYESPAMTIDDLLVALARAGVPKFVDAARAKLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIC1</accession>
    <name>A0A1Q2CIC1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plasmid stabilization protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14560</name>
        <name evidence="3" type="ORF">SAMN05428934_109102</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14560"/>
    <dbReference type="EnsemblBacteria" id="AQP45878">
        <property type="protein sequence ID" value="AQP45878"/>
        <property type="gene ID" value="RPIT_14560"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06548">
        <property type="protein sequence ID" value="SDZ06548"/>
        <property type="gene ID" value="SAMN05428934_109102"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14560"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ06548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="109" mass="12359" checksum="3A7F7CC3A4AFD38F" modified="2017-04-12" version="1">MPEAWSEKRERQYEHIKEGLLDRGEDEDTAEEIAARTVNKERARAGESEEASRSSLDDISSGRRGGLRSHKGAQGRTRDQLYNEARQMGIEGRSKMNKAELQRAVDAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIH0</accession>
    <name>A0A1Q2CIH0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">1-acyl-sn-glycerol-3-phosphate acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14400</name>
        <name evidence="3" type="ORF">SAMN05428934_11262</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ15347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14400"/>
    <dbReference type="EnsemblBacteria" id="AQP45850">
        <property type="protein sequence ID" value="AQP45850"/>
        <property type="gene ID" value="RPIT_14400"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ15347">
        <property type="protein sequence ID" value="SDZ15347"/>
        <property type="gene ID" value="SAMN05428934_11262"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14400"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="54"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ15347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="267" mass="29374" checksum="4C4A41885FE93B5B" modified="2017-04-12" version="1">MAKDVEPGGSRYTSDLQAATRRTAQLLLLKPALWKLLKIHVHSAANLDSLEAPFIVFSNHASHLDAPLILCSLPSRLGRFVATGAAGDFFYDKWWKSAPMSLFMNGFPIDRGKGGRGQRGLSAKLLDDGVPLLLFPEGTRSRDGAMGPYKPGVASLCISRGVPALPVALVGAFEAWPSKQKHLPKGRPEVHVVFGRPMTPFPGEIAHEFNERMRRQVIELHDTTARAYGMKTLAEYAHTQALERAQKSEIAALVDDAKQRADKQEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIJ0</accession>
    <name>A0A1Q2CIJ0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14860</name>
        <name evidence="3" type="ORF">SAMN05428934_10948</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14860"/>
    <dbReference type="EnsemblBacteria" id="AQP45927">
        <property type="protein sequence ID" value="AQP45927"/>
        <property type="gene ID" value="RPIT_14860"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05513">
        <property type="protein sequence ID" value="SDZ05513"/>
        <property type="gene ID" value="SAMN05428934_10948"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14860"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="SSF55826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_edit" evidence="1">
        <location>
            <begin position="42"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ05513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="178" mass="18705" checksum="852E38D1C4D3A064" modified="2017-04-12" version="1">MPSAEGNLDWNPLADHPELVAHPVAQASHRVPDARVAEIDEALADTAAFCERYDVALEASANCVVVFGRRGEETVHAAVMVLAVDRADVNKTVRKELGMRKMSFADQPTVEQLTGMTQGGITPVGLPDGWPILIDEAVVSAGPVVIGGGVRGSKILLDGADLARLPGAKVIPLALRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIM7</accession>
    <name>A0A1Q2CIM7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Drug:proton antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02625"/>
    <dbReference type="EnsemblBacteria" id="AQP45979">
        <property type="protein sequence ID" value="AQP45979"/>
        <property type="gene ID" value="RPIT_02625"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02625"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011777">
        <property type="entry name" value="Geranylgeranyl_Rdtase_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02032">
        <property type="entry name" value="GG-red-SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="13"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="428" mass="45933" checksum="366169E65AC5D6E0" modified="2017-04-12" version="1">MPDGAAPAYPTEEADVIVVGAGPAGATTAAYLARYGLSVTMLEKSTFPRDKVCGDGLTPRATRALTRLGIDLSDETQWHRNIGLRSWGVHPYPFEFKWPELTDFPPFGVARARKDFDEVLARFAVAQGAALIEGAAAESPILNDRTGRIEGVVTKDGRRFRAPYVVAADGVSSRLAVAMGITKREDRPMGVAYRTYYRTPKGDDDHLESYLTLWDGEPGKSNQMPGYGWMFPLGGGIANVGLGVLNTGKSVQQTDLRGLLKNWAASAPEAWGYRDAEEIGKIQGAALPMAFNRTPHYGRGLLLVGDSGGMVSPFNGEGIAYAMEAAEAAASAVAEAISRGVGTGSAERAMQAYPAVMKESLGGYYRLGVTFSKLIGDPRIMHLCVKYGLPRKTLMNFVMKLLAHLTDSHDGDATDRIINALSKAVPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIN2</accession>
    <name>A0A1Q2CIN2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dihydropteroate synthase</fullName>
            <shortName evidence="1">DHPS</shortName>
            <ecNumber evidence="1">2.5.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Dihydropteroate pyrophosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DHPS family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.15" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01595"/>
    <dbReference type="EnsemblBacteria" id="AQP45964">
        <property type="protein sequence ID" value="AQP45964"/>
        <property type="gene ID" value="RPIT_01595"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01595"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00156"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004156">
        <property type="term" value="F:dihydropteroate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="PTHR20941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01496">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00792">
        <property type="entry name" value="DHPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pterin-binding" evidence="2">
        <location>
            <begin position="23"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="294" mass="31418" checksum="1111AFF7D4052130" modified="2017-04-12" version="1">MRPTITAAQRRIGGREFDFDRRAAVMAIVNRTRDSFFDDGRTYDLQPAVDAALAAIEAGADIVDVGGVPFSPIAREVSESEEIDLIVGFVEEVLSQAPTAVLSVDTFRSAVAGAAVGAGAAIINDTSGLADPALAEVAAKSGATIVITHSKAVPRTLLPSPRYDDVVREVSEFLSLRVQQAVDAGVTPAQLIVDPGPDLNKNTLHTLEIVRRFDEFARLGPPLLAALSNKDFVGETVDRPKRERLPGTLVATAWCLERGARIVRAHDVAATVDAVRMAEALLGLREPTNLRHNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIQ1</accession>
    <name>A0A1Q2CIQ1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pyruvate formate-lyase-activating enzyme</fullName>
            <ecNumber evidence="9">1.97.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_02970</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>glycyl-[formate C-acetyltransferase] + reduced [flavodoxin] + S-adenosyl-L-methionine = 5'-deoxyadenosine + glycin-2-yl radical-[formate C-acetyltransferase] + H(+) + L-methionine + semiquinone [flavodoxin]</text>
            <dbReference type="Rhea" id="RHEA:19225"/>
            <dbReference type="Rhea" id="RHEA-COMP:10622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12190"/>
            <dbReference type="Rhea" id="RHEA-COMP:12191"/>
            <dbReference type="Rhea" id="RHEA-COMP:14480"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29947"/>
            <dbReference type="ChEBI" id="CHEBI:32722"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:140311"/>
            <dbReference type="EC" id="1.97.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the organic radical-activating enzymes family.</text>
    </comment>
    <dbReference type="EC" id="1.97.1.4" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02970"/>
    <dbReference type="EnsemblBacteria" id="AQP45987">
        <property type="protein sequence ID" value="AQP45987"/>
        <property type="gene ID" value="RPIT_02970"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02970"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043365">
        <property type="term" value="F:[formate-C-acetyltransferase]-activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012838">
        <property type="entry name" value="PFL1_activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001989">
        <property type="entry name" value="Radical_activat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02493">
        <property type="entry name" value="PFLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01087">
        <property type="entry name" value="RADICAL_ACTIVATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="8 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="12" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="11">
        <location>
            <begin position="62"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP45987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="289" mass="31920" checksum="73ED86800D1B0A86" modified="2017-04-12" version="1">MDVREGVTGEYRPGRSAAVERPRGRGFGDLPALLELGRSDELAGVRDGSAAWLHSWELVTSVDGPGTRLTIFLNGCPLRCQYCHNPDTMRTRQGQLVSLEEIVAKLHRYRRVFRATRGGLTISGGEPMMQPAFVQRLLRAAKELGIHTAMDTSGNLGGRVNSEIMDDLDLVLLDVKSGDPATYRRVTGADLAPTLEFGDRLSRAGVETWVRFVLVPGLTDDEANVRLAARHVAAWGSVSRVEVLPFHQMGRDKWANLGLTYELEGTQPPTPELLERVRAQFRSEGLTVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIQ3</accession>
    <name>A0A1Q2CIQ3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exodeoxyribonuclease III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_02760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02760"/>
    <dbReference type="EnsemblBacteria" id="AQP45984">
        <property type="protein sequence ID" value="AQP45984"/>
        <property type="gene ID" value="RPIT_02760"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02760"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008853">
        <property type="term" value="F:exodeoxyribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037493">
        <property type="entry name" value="ExoIII-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43250">
        <property type="entry name" value="PTHR43250"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00633">
        <property type="entry name" value="xth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="293" mass="33002" checksum="6764EBD44B80839F" modified="2017-04-12" version="1">MRIGTHNVNGIRAALRRGFRDYWDGSGADVVALQEVRCRVDDLPLDAFEGFHVSLDAGQLAGRNGVAVLTRQAPVRVRSLSGAVTAIASDRATSALAAERIVNRDLAVFADEGRYLEVDLADAPLRVASLYLPKGAAWPFDDGAEVKYRRKMRFLKGLARQLTASRRDAAAEGREFLIMGDFNIAHTRQDLRNWRSNQRSEGFLPEEREWFASILSPRTLVDVTRRLHPEADGPYSWWSWRGQSFTQDTGWRIDYHLASPRLARSASASWVAREATYDLRMSDHSPVLADYRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIQ4</accession>
    <name>A0A1Q2CIQ4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01370"/>
    <dbReference type="EnsemblBacteria" id="AQP45953">
        <property type="protein sequence ID" value="AQP45953"/>
        <property type="gene ID" value="RPIT_01370"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01370"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:CoA pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03426">
        <property type="entry name" value="CoAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045121">
        <property type="entry name" value="CoAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992">
        <property type="entry name" value="PTHR12992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="22"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="202" mass="21857" checksum="156806BFD29C02F8" modified="2017-04-12" version="1">MSAALVAGPVTRQIGIDRRPKGERSAAVLMLFTDEPDPSLTFVTRAETMRRHAGQIALPGGAADDTDPSLQFTALREANEEIGLASEHVTILGELPALWVPASRYDVTTVVAVWPGGHPLEAVDPAETGAVHSYRVSELAAPDARVMGRHPLGFEGPAFVLGEQFIWGLTGHLVDWGLDLGGWATDWDRFRVVDVPARFLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIS2</accession>
    <name>A0A1Q2CIS2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase H</fullName>
            <ecNumber evidence="6">2.1.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA m(4)C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytosine-N(4)-)-methyltransferase RsmH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmH</name>
        <name evidence="7" type="ORF">RPIT_03990</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(4)-methylcytidine(1402) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="Rhea" id="RHEA-COMP:10287"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74506"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the methyltransferase superfamily. RsmH family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.199" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03990"/>
    <dbReference type="EnsemblBacteria" id="AQP46004">
        <property type="protein sequence ID" value="AQP46004"/>
        <property type="gene ID" value="RPIT_03990"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03990"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071424">
        <property type="term" value="F:rRNA (cytosine-N4-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01007">
        <property type="entry name" value="16SrRNA_methyltr_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002903">
        <property type="entry name" value="RsmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023397">
        <property type="entry name" value="SAM-dep_MeTrfase_MraW_recog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11265">
        <property type="entry name" value="PTHR11265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01795">
        <property type="entry name" value="Methyltransf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004486">
        <property type="entry name" value="MraW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81799">
        <property type="entry name" value="SSF81799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00006">
        <property type="entry name" value="TIGR00006"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6">
        <location>
            <begin position="28"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP46004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="308" mass="33573" checksum="4836A9CEE2250522" modified="2017-04-12" version="1">MRDRIVELLRPALTAPGAVYVDGTLGLAGHAIAILEACPSARLIGIDRDPDAHEVARERLGHLADRATLVQAVYDELPEVLEDLGVDTVDAILLDLGLSSLQIDRTDRGFAYRVDSPLDMRMNQGEGQTAADVLNTYSSRDLSRILRRYGEERFADRIARAVVAAREAEPFRTSARLVETISAAIPAAARHTGGHPAKRTFQALRIEVNRELAALEAALPAAVGALAVGGRMAVLSYHSLEDRLVKRTFAERATDRGPRDMPVVPDHLRAELALLTRGAERPDQHEIDTNPRAASARLRVAQRVKEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIV6</accession>
    <name>A0A1Q2CIV6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_05950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP46042">
        <property type="protein sequence ID" value="AQP46042"/>
        <property type="gene ID" value="RPIT_05950"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05950"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP46042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="252" mass="26114" checksum="69A1FB907BE4646D" modified="2017-04-12" version="1">MSFSLEGKVALVTGASKGIGQAIARALADAGALVACTARSRSSLDETLRLISDEGGIAIPVEWDVRDPHAAQPAVDLVERELGPLALAVNNAGIGAGTPALDITPDQWRSVYETNVDGLFWSCQAEGRAMIANGGGAIVNIASISGSIANRNLTQAQYNSGKAAVIHLTKSLAVEWAPVGIRVNSVSPGYTRTPMNERPEVADLVAEFADTTPLGRLAEPGEIAGPVTFLLSPAASYITGADLLVDGGYCCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIV7</accession>
    <name>A0A1Q2CIV7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Galactokinase</fullName>
            <ecNumber evidence="11">2.7.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Galactose kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">galK</name>
        <name evidence="15" type="ORF">RPIT_06775</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>alpha-D-galactose + ATP = ADP + alpha-D-galactose 1-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13553"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28061"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58336"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="11">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the GHMP kinase family. GalK subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.6" evidence="11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06775"/>
    <dbReference type="EnsemblBacteria" id="AQP46059">
        <property type="protein sequence ID" value="AQP46059"/>
        <property type="gene ID" value="RPIT_06775"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06775"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004335">
        <property type="term" value="F:galactokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00246">
        <property type="entry name" value="Galactokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000705">
        <property type="entry name" value="Galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022963">
        <property type="entry name" value="Galactokinase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019741">
        <property type="entry name" value="Galactokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019539">
        <property type="entry name" value="GalKase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006206">
        <property type="entry name" value="Mevalonate/galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10457:SF6">
        <property type="entry name" value="PTHR10457:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10509">
        <property type="entry name" value="GalKase_gal_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000530">
        <property type="entry name" value="Galactokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00473">
        <property type="entry name" value="GALCTOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00131">
        <property type="entry name" value="gal_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00106">
        <property type="entry name" value="GALACTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="6 11 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GalKase_gal_bdg" evidence="14">
        <location>
            <begin position="7"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_N" evidence="12">
        <location>
            <begin position="109"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="13">
        <location>
            <begin position="275"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="11">
        <location>
            <begin position="31"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="118"/>
            <end position="124"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="11">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF10509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="AQP46059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="377" mass="39771" checksum="E35822FF54893211" modified="2017-04-12" version="1">MAALADRFRSLTGSEPEGFWFAPGRVNLIGEHTDYNDGFVLPFALERKAVLAAGRRHDDQLVIASLELNEDVTIALKDLAPGVGGWDAYLAGVVWALREAGHAVGGATLVLSSDVPLGAGLSSSAAIECATVAALVDLYGLTIEKMDRARVAQVAENAYVGAPTGLLDQAASTLCEADAGLFLDCRTLDTEQVPLPMAAQALEILVLDTKTPHSHVDGEYGTRRRTCEEAAEILGVDALRDVTDLDAALAQLDDDTMRRRVRHVVTENARVLDALALAREGDLEALAPLLDASHASMRDDYEITVPTVDLAVETAREAGALGARMTGGGFGGCIIALVRAGDADRIGQRIAEAFSEAGYGRPEWFAATPAPGAGQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIZ8</accession>
    <name>A0A1Q2CIZ8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7 8">Pantothenate kinase</fullName>
            <ecNumber evidence="4 7 8">2.7.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Pantothenic acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">coaA</name>
        <name evidence="10" type="ORF">RPIT_10090</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7 8">
            <text>(R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16373"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7 8">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7 8">Belongs to the prokaryotic pantothenate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.33" evidence="4 7 8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10090"/>
    <dbReference type="EnsemblBacteria" id="AQP46118">
        <property type="protein sequence ID" value="AQP46118"/>
        <property type="gene ID" value="RPIT_10090"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10090"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00352"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004594">
        <property type="term" value="F:pantothenate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02025">
        <property type="entry name" value="PanK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00215">
        <property type="entry name" value="Pantothen_kinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004566">
        <property type="entry name" value="PanK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285:SF139">
        <property type="entry name" value="PTHR10285:SF139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000545">
        <property type="entry name" value="Pantothenate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00554">
        <property type="entry name" value="panK_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7 8" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PRK" evidence="9">
        <location>
            <begin position="94"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="99"/>
            <end position="106"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP46118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="321" mass="35928" checksum="D831C3B139CA4902" modified="2017-04-12" version="1">MARVHDHEGVPVPGPYVTLDRRAWADLADATEIDLDEETLARLRGIGDPTSVRDIAEVYRPLTQLLHLHMANTGRLFAQSNDFLGLNERRTPFVIAVAGSVAVGKSTVSRLLQELLRRAPGSPRVDLVTTDGFLYPNSELEQRGLLENKGFPESYNRRALLEFVMAVKSGEPRVTAPVYSHMIYDIAEGEHVVVESPDILILEGLNVLQPARTVADGGTGLAVSDFFDFSVFVDADEDHIKAWFMERFMELRRTAFTDERSFFKRFTELSDEEAVAVGEQVWEETNGPNLRENIAPTRGRATAILLKDHTHAIDSIMIRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ09</accession>
    <name>A0A1Q2CJ09_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Signal peptidase I</fullName>
            <ecNumber evidence="3 5">3.4.21.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_08560</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Membrane</location>
            <topology evidence="5">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the peptidase S26 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="3 5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08560"/>
    <dbReference type="EnsemblBacteria" id="AQP46092">
        <property type="protein sequence ID" value="AQP46092"/>
        <property type="gene ID" value="RPIT_08560"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08560"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019757">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Lys-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390">
        <property type="entry name" value="PTHR43390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02227">
        <property type="entry name" value="sigpep_I_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00760">
        <property type="entry name" value="SPASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S26" evidence="6">
        <location>
            <begin position="2"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP46092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="233" mass="24805" checksum="94C78D531EBFAC11" modified="2017-04-12" version="1">MTESVLILVGAIVIATLLRSFVGQMFVIPSGSMENTLQVNDRVLVAKFGGFQRGDVVVFEDPGNWLAPSMPSDNPIKIALEFVGVLPNSGTEHLIKRVIGMPGDRVRYSADVGKVEVNGHALDESAYLYATDGVQVAPATVPFEIIVPADHIFVMGDHRNASADSRCRLGNISQSPGQSAFVPVEKVVGAAVAIVAPLDRLATFNLPETFDEVPPAAQPAPTEPDLIYVEPGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ48</accession>
    <name>A0A1Q2CJ48_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized conserved protein YlxW, UPF0749 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_12720</name>
        <name evidence="4" type="ORF">SAMN05428934_104143</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0749 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY78951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12720"/>
    <dbReference type="EnsemblBacteria" id="AQP46156">
        <property type="protein sequence ID" value="AQP46156"/>
        <property type="gene ID" value="RPIT_12720"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY78951">
        <property type="protein sequence ID" value="SDY78951"/>
        <property type="gene ID" value="SAMN05428934_104143"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12720"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010273">
        <property type="entry name" value="DUF881"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37313">
        <property type="entry name" value="PTHR37313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05949">
        <property type="entry name" value="DUF881"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544531" evidence="2">
        <location>
            <begin position="21"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY78951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="227" mass="24070" checksum="BD2650CC62BE9C77" modified="2017-04-12" version="1">MTTVLVCLLAGLMMTVASIAARGTDLRSDRTANLRDLIVTQGNRNTELRTEAEALRDEVEQLSAQRFGAPPVDRASTALEVAAGLVAVSGPGFRVVLTDAPNDVRPAGVDDDSLVVHQQDIQAVVNAMWAGGAEAVTIQGQRVIATTGIKCVGNTVVLHGIPYAPPYVIEAIGDVNQIEASIDASEHIQVYLQYVDAYGLGYEEQRLNQIDMPAFAGSVGVTLARSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ78</accession>
    <name>A0A1Q2CJ78_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfate adenylyltransferase subunit 2</fullName>
            <ecNumber evidence="2">2.7.7.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">ATP-sulfurylase small subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Sulfate adenylate transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_00010</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PAPS reductase family. CysD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.4" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00010"/>
    <dbReference type="EnsemblBacteria" id="AQP46198">
        <property type="protein sequence ID" value="AQP46198"/>
        <property type="gene ID" value="RPIT_00010"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00010"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019419">
        <property type="term" value="P:sulfate reduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011784">
        <property type="entry name" value="SO4_adenylTrfase_ssu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002936">
        <property type="entry name" value="CysDAde_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02039">
        <property type="entry name" value="CysD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAPS_reduct" evidence="6">
        <location>
            <begin position="36"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP46198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="306" mass="35061" checksum="32991DCC958D0B48" modified="2017-04-12" version="1">MSEVEELPTRTLSHLEALESESIHIFREIVSELERPVLLFSGGKDSIVMLHIAAKAFWPAPVPFPVLHVDTGHNFPEVLAHRDATVERLKLRLVVAHVQDYIDDGRLLERADGTRNPLQTQPLLDAITEGRFDAVFGGGRRDEEKARAKERVVSLRDEFGQWDPRNQRPELWNLYNPRHRPGEHVRVFPLSNWTELDVWRYIASENIDLPALYYAHERDVFSRDGMWLAVGDVSQPRDGERVERRLVRYRTVGDMSCTGAVESDALTVADVIEEVALTRITERGATRADDRVTEAAMEDRKKEGYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBF7</accession>
    <name>A0A1Q2CBF7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00205"/>
    <dbReference type="EnsemblBacteria" id="AQP43437">
        <property type="protein sequence ID" value="AQP43437"/>
        <property type="gene ID" value="RPIT_00205"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00205"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="67" mass="7641" checksum="687C6D10733288D1" modified="2017-04-12" version="1">MWRGPVWVNTNWLVAQGLRRQGLIDKAERLERATLELVAAQGPNEYFRPDTGVKPRGPRRCSDGPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBH1</accession>
    <name>A0A1Q2CBH1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00295</name>
        <name evidence="3" type="ORF">SAMN05428934_10513</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY83731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00295"/>
    <dbReference type="EnsemblBacteria" id="AQP43448">
        <property type="protein sequence ID" value="AQP43448"/>
        <property type="gene ID" value="RPIT_00295"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY83731">
        <property type="protein sequence ID" value="SDY83731"/>
        <property type="gene ID" value="SAMN05428934_10513"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00295"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="7"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY83731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="68" mass="7719" checksum="CF93F1588F88CA83" modified="2017-04-12" version="1">MPLNKRMRMARVALDLTQQDLAKQVGVSRQTISMIEAGDHNPTLNLCIDICKSLKTDLNTLFWEESSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBH3</accession>
    <name>A0A1Q2CBH3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="3">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_00360</name>
        <name evidence="8" type="ORF">SAMN05428934_10526</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY84091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00360"/>
    <dbReference type="EnsemblBacteria" id="AQP43456">
        <property type="protein sequence ID" value="AQP43456"/>
        <property type="gene ID" value="RPIT_00360"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY84091">
        <property type="protein sequence ID" value="SDY84091"/>
        <property type="gene ID" value="SAMN05428934_10526"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00360"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="8" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="5">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="6">
        <location>
            <begin position="172"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="78"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="226"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="226"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY84091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="507" mass="53925" checksum="3C955319754452AF" modified="2017-04-12" version="1">MKREFLLPDPGEGLLEAEIVAWRVAEGDVIEVNDVLVEIETAKSLVELPSPFAGTVTRLIVAEGTTVEVGAPIVEIDDGADAPDEAAGPNLVGYGASDTGAARRRRRGQPDRGSVSDAMSAAYEQHEPGRRADEVHPAGTVHAQASGDPLPTPGRAPSESQLVLASDPGDARAKPPVRKYAKDLGVDLNSVVGTGPDGTVTRRDVEAAAAFRMLDDEPKQGRILNDQASFQGSPSGAPGGQSHAGTSFSGSAFGGGFGPTEGLGGFDPNQGRAERRVPIKGVRKVTADNMVKSVNTHVHVTEWITIDVTGTMEFVETLKQRREFTGLRVSPLLVYAKAICLALTRNPDLNTSWDEERQEIVYYGDINLGIAAATPRGLMVPNIKGAQRLSLLQLCQAINQLVQVSREGKLQPGDYSQGTFTITNVGVFGIDAGTPIINGDESAIFCMGSIERRPWVVGEGADEKVVPRWVTTLAVAFDHRIVDGEQGSRFLHDVASILAEPALALLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBJ8</accession>
    <name>A0A1Q2CBJ8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glyco_trans_2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43479">
        <property type="protein sequence ID" value="AQP43479"/>
        <property type="gene ID" value="RPIT_00480"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00480"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="24"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="161" mass="17066" checksum="F722A2CC93D975BE" modified="2017-04-12" version="1">MSDLELSYVIPFKDWGLRRIGLAVESARASLGGIPGEVIVSDYGSEFEGEELDHFRSYLESRGAVYVRTETDGVWSRSRALNAGMAVARGRVLVAADADMVVPPDCLQRTAEIIGADPNLASSTAASTFLPTGGTRRSRTGASTGRRCVASRPCGPGGGWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBM1</accession>
    <name>A0A1Q2CBM1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Potassium transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00635</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00635"/>
    <dbReference type="EnsemblBacteria" id="AQP43506">
        <property type="protein sequence ID" value="AQP43506"/>
        <property type="gene ID" value="RPIT_00635"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00635"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="1">
        <location>
            <begin position="4"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="2">
        <location>
            <begin position="134"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="215" mass="23124" checksum="4D18E9B9162F1BB4" modified="2017-04-12" version="1">MADHVVVIGLGRFGESVALELMATGADVLGIDIGEDPVARMNARLTHAVQADATREEVLRQLGVDEAEYVVVAIGDSIEASLLTSSLVLSFGVPQLWAKAVSDAHGRILEQIGVHHVVHPEREIGRRVAHLLRARLQDYIELGGGYALVRTTPPAAVIGRPIREIHVRRNFGVTVIASKGSDGDWKDVTGDTVLADGDEILLTGPIAKAERFHLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBP8</accession>
    <name>A0A1Q2CBP8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UPF0056 membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_00745</name>
        <name evidence="9" type="ORF">SAMN05428934_105102</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the UPF0056 (MarC) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00745"/>
    <dbReference type="EnsemblBacteria" id="AQP43527">
        <property type="protein sequence ID" value="AQP43527"/>
        <property type="gene ID" value="RPIT_00745"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86145">
        <property type="protein sequence ID" value="SDY86145"/>
        <property type="gene ID" value="SAMN05428934_105102"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00745"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002771">
        <property type="entry name" value="Multi_antbiot-R_MarC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33508">
        <property type="entry name" value="PTHR33508"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01914">
        <property type="entry name" value="MarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00427">
        <property type="entry name" value="TIGR00427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP43527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY86145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="196" mass="21594" checksum="D38FA14CD6E5A339" modified="2017-04-12" version="1">MTMLSAAMTFFLVMDPLGNVPLFLAALRKTAPERRQWVILRECLIALAIMVTFLFVGRFFLELLHIENASLQAAGGVILMLIAVRMIFPTPERPLHEPMTHDEPFIVPLAVPYVAGPSLLAVEVVLVSQNPSGWPIFLGALIAAWLVGTLILYSSGFLRRAVGERALIAVERLMGMILVVLGVQMLFDGIDTFFTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBQ1</accession>
    <name>A0A1Q2CBQ1_9ACTN</name>
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            <fullName evidence="3">Putative intracellular protease/amidase</fullName>
        </submittedName>
        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00460</name>
        <name evidence="3" type="ORF">SAMN05428934_10546</name>
    </gene>
    <organism evidence="2 4">
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
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            <taxon>Propionibacteriales</taxon>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY84662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00460"/>
    <dbReference type="EnsemblBacteria" id="AQP43475">
        <property type="protein sequence ID" value="AQP43475"/>
        <property type="gene ID" value="RPIT_00460"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY84662">
        <property type="protein sequence ID" value="SDY84662"/>
        <property type="gene ID" value="SAMN05428934_10546"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00460"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="1">
        <location>
            <begin position="32"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY84662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="236" mass="24994" checksum="3E441B0340E38B9D" modified="2017-04-12" version="1">MSKTTPARVLIVTTSTPSYERAGYRTGLWLGELTHFWDVLEKDGHHLTIASVDGGQVPIDPESLSAPVLAMGGTKKRYEDTGFMSILDDTASLDDVASDGWDAVYLTGGHGTMFDFPYNPVLADLLVTTYEAGGIVAAVCHGPAGFVGATGSDGNPLIAGKKVTGFSWPEEKLAGRDKVVPFRLDHALKEEGATYTKALRPMAEKVVRDGTLVTGQNPTSAEGVGKAVAKLLAKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBU3</accession>
    <name>A0A1Q2CBU3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Carbohydrate ABC transporter membrane protein 1, CUT1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_01065</name>
        <name evidence="7" type="ORF">SAMN05428934_105164</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01065"/>
    <dbReference type="EnsemblBacteria" id="AQP43583">
        <property type="protein sequence ID" value="AQP43583"/>
        <property type="gene ID" value="RPIT_01065"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87815">
        <property type="protein sequence ID" value="SDY87815"/>
        <property type="gene ID" value="SAMN05428934_105164"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01065"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="86"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY87815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="302" mass="33519" checksum="91F12BD552F0F089" modified="2017-04-12" version="1">MSTTTVTPPKRRSGVRTSRSDRIVLTLMLAVPLLIVLGLIWGPALITVALSFTTWDGIGSLDTIKFVGVQNYVDLATIYPPFWPALWHNVLWLIVLFAVFTPLGMFLAILLDKELRGTKFYQTALYLPVVLSAALVGFIWQLMYSRDQGLINAMLGTTIDWYGDPSINLWAAMVANGWRHTGYIMLLYLSGLKGVDPALREAAQIDGANQRQTYLRIIFPVMRPINIIVLTITVIEGLRAFDLAWIINRGRNGLELISTLVTTNVIGEASRIGFGSALATIMLLISSVFIVIQLRVVMKGDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBU7</accession>
    <name>A0A1Q2CBU7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01030</name>
        <name evidence="4" type="ORF">SAMN05428934_105157</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01030"/>
    <dbReference type="EnsemblBacteria" id="AQP43577">
        <property type="protein sequence ID" value="AQP43577"/>
        <property type="gene ID" value="RPIT_01030"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87621">
        <property type="protein sequence ID" value="SDY87621"/>
        <property type="gene ID" value="SAMN05428934_105157"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01030"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY87621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="178" mass="18063" checksum="5062C20381C45D33" modified="2017-04-12" version="1">MFPWIANWGLTLAGNVMRALGTNAGEVGFDALEATGTNYNGLYALGNGAPLTSLIWGCIAIFAIRNRTVAAAISAGVGGVLAFFGIIHAGAPVLGGETPTSFLIAYAMVAALFVLKWFLDKRDPSLAGGAPADEDHVPAAAVATASTSSDPVLDGTERAAVGDAAHTDPAPARARPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBW3</accession>
    <name>A0A1Q2CBW3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HAD family hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">NagD protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01105</name>
        <name evidence="4" type="ORF">SAMN05428934_105172</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAD-like hydrolase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY88033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01105"/>
    <dbReference type="EnsemblBacteria" id="AQP43590">
        <property type="protein sequence ID" value="AQP43590"/>
        <property type="gene ID" value="RPIT_01105"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY88033">
        <property type="protein sequence ID" value="SDY88033"/>
        <property type="gene ID" value="SAMN05428934_105172"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01105"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000915">
        <property type="entry name" value="PGP-type_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="17"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY88033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="263" mass="28259" checksum="64D3D9A36A3A4715" modified="2017-04-12" version="1">MTDITRSPHDIECWLTDMDGVLVHEDHALPGAVELIDSWLATSRRFLVLTNNSTWTPRDLAARLERAGLHVPEENLWTSAMATAAFLGGQPGKKTAFVIGEAGLTSALHDAGFILTDVDPDYVVLGETRNYSFEAITRAIRLVLAGARYIVTNPDATGPSVDGVLPATGAVAAMITAATKRKPYVVGKPNPMMFRSAMNRIAAHSESTAMIGDRMDTDIVAGMEAGLHTVLVLSGLTTIADVETYPFRPDQVISSVAELLDQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBX1</accession>
    <name>A0A1Q2CBX1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">YkuD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_01170</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01170"/>
    <dbReference type="EnsemblBacteria" id="AQP43602">
        <property type="protein sequence ID" value="AQP43602"/>
        <property type="gene ID" value="RPIT_01170"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01170"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="YkuD" evidence="3">
        <location>
            <begin position="181"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="291" mass="32319" checksum="6E0F4186DFD1DA09" modified="2017-04-12" version="1">MTPGYHYVNGRYWFTECSEYSSTVVRCQTEIFASTIVLKSGQWYKQNNWVFNNLAYLPSPESNWTNNDLGRNGEWTAADGRQWRTECHTPATGRGACRNYAVATVASLKDGKVIQRNVELLNSIVNFSTPTRPWVRSIPATNPNPPANVPTPSTPQPIIANPLVQQGFRLDSRCLTGRGFCVSKSQRKMAWVVNGKVDVVLDVRFGGELTPTRNGAWSIGWKSRNHVSSIYGSAMPYAMFFSGGQAIHYSEDFATRGYNGSSAGCVNVRDKAAIARLFDIARVGDKVIVYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC12</accession>
    <name>A0A1Q2CC12_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helicase/secretion neighborhood TadE-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01435</name>
        <name evidence="3" type="ORF">SAMN05428934_10835</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43641">
        <property type="protein sequence ID" value="AQP43641"/>
        <property type="gene ID" value="RPIT_01435"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01604">
        <property type="protein sequence ID" value="SDZ01604"/>
        <property type="gene ID" value="SAMN05428934_10835"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01435"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ01604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="121" mass="11795" checksum="C3D9FBC1858DCEA1" modified="2017-04-12" version="1">MRGERGSAGSVLLAAMLTVIATVLLSGVLVISWFGAVRSADQVAELAALAGASAAVTGEDACRAAAATAGRNGFPVHACVVRGGGSHVVVEVTVAAELEGAFPGAPRRVLRVAAAGTVGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC53</accession>
    <name>A0A1Q2CC53_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphate transport system permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_01765</name>
        <name evidence="13" type="ORF">SAMN05428934_108101</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01765"/>
    <dbReference type="EnsemblBacteria" id="AQP43693">
        <property type="protein sequence ID" value="AQP43693"/>
        <property type="gene ID" value="RPIT_01765"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02857">
        <property type="protein sequence ID" value="SDZ02857"/>
        <property type="gene ID" value="SAMN05428934_108101"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01765"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011864">
        <property type="entry name" value="Phosphate_PstC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02138">
        <property type="entry name" value="phosphate_pstC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="86"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP43693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDZ02857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="327" mass="34766" checksum="F4EB5924EC6586D3" modified="2017-04-12" version="1">MSPTDAAPAAGTRPDSEPHSLQRSAKRFGDTVFRSLSTGSGILILLILAAVASFLVGLALPALLADPAELQFGRGVSFWEYVAPYAFGTMWSSILAMLVAVPVAVGIALYLTHYAPKRVASTFGYVIDLLAAVPSVVFGLWGIAVLAPALRPLFLWLEENLGFIPLFSGPVSGTGRTILTASLVLAVMILPIITAISREVFLQTPRLHEEASLALGATRWEMIRQAVIPFGMPGIISACMLGLGRALGETMAVAMVLSGSEVISIQLLTSQNPNTIAANIAQSFPEAHDIGRNQLIATGLVLFVITLAVNMTARWIINRRKEFSGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCD8</accession>
    <name>A0A1Q2CCD8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adenylyltransferase and sulfurtransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02165</name>
        <name evidence="3" type="ORF">SAMN05428934_10131</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY23234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02165"/>
    <dbReference type="EnsemblBacteria" id="AQP43764">
        <property type="protein sequence ID" value="AQP43764"/>
        <property type="gene ID" value="RPIT_02165"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY23234">
        <property type="protein sequence ID" value="SDY23234"/>
        <property type="gene ID" value="SAMN05428934_10131"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02165"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="PTHR10953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ThiF" evidence="1">
        <location>
            <begin position="17"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY23234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="257" mass="27575" checksum="6C0F72312AABCBCE" modified="2017-04-12" version="1">MVAVPVMGLSTAQRERYLRNIDVVGFGTDGQERLLDSSVLVIGAGGLGSAALPYLAAAGVGRIGVVDGDAVELKNMQRQVLHTELGRNKAESAAQRLRALNPDVHVDVFPEFLTYERACELFVDYDLVMDCCDTFGAKFMLSDAAEAVGARLIWASAVGMQGQCSVFGVPDEHGERLYLRDLIPTEPDPDDYPKATEIGVLGAMVGQIGALEATEAIKLLAGFGEPLVGRVMVLDALRGRWDVLSLRKAPRQTRSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCL8</accession>
    <name>A0A1Q2CCL8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_02725</name>
        <name evidence="2" type="ORF">SAMN05428934_101145</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY26621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43862">
        <property type="protein sequence ID" value="AQP43862"/>
        <property type="gene ID" value="RPIT_02725"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY26621">
        <property type="protein sequence ID" value="SDY26621"/>
        <property type="gene ID" value="SAMN05428934_101145"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02725"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY26621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="491" mass="52267" checksum="02D9C3F794C7996F" modified="2017-04-12" version="1">MIRQEGGRFSASNGWAFNNLTYAASPRGLWTTNPLAAYGKVGGAATWTGTDGRTWRTECDTPLTGNGGCRSFIVASVIVASVIEASGSGYRWVTKEIFNSMVRFGSTAPPSYPTAPPMTQAPSFLQGRTHFRLGLIVTQANVGTQAKGHARLSNIELDPGGKVGTFRENYWTYSMDMAAGEYDFGQFRATLANLPSGCVTSSRETADRASIGLPPLPPGACDVRAARTFLGAPTVRTGTYHASSGATGNRIQLFFEGSSVTETYLDASDPGRAYSELRLSAHTHPGAINSIGFLFGSTTAPTVGQSLAPLVQQLAEWLPPRSVNPAHVNQALFPSPAGGADKSLWVQSLGSSALPGHPQYFRFRQYVPTQGNPGCIATEPAVRSRIDYGWHSYLCPLGSDGKMAWHHMVSPLVAERHGLCTDASSYACKQAGTQTADYTMPARAGGHVNQTLQVIDDDGRLVGMVGLETSLYSLKATSQSQLSLIAVVASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCS7</accession>
    <name>A0A1Q2CCS7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8 11">50S ribosomal protein L22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rplV</name>
        <name evidence="12" type="ORF">RPIT_03065</name>
        <name evidence="13" type="ORF">SAMN05428934_101214</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="7">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="8 11">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8 10">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY28686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03065"/>
    <dbReference type="EnsemblBacteria" id="AQP43919">
        <property type="protein sequence ID" value="AQP43919"/>
        <property type="gene ID" value="RPIT_03065"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY28686">
        <property type="protein sequence ID" value="SDY28686"/>
        <property type="gene ID" value="SAMN05428934_101214"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03065"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01331_B">
        <property type="entry name" value="Ribosomal_L22_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_L22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018260">
        <property type="entry name" value="Ribosomal_L22/L17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_L22/L17_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005727">
        <property type="entry name" value="Ribosomal_L22_bac/chlpt-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501">
        <property type="entry name" value="PTHR13501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="SSF54843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01044">
        <property type="entry name" value="rplV_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00464">
        <property type="entry name" value="RIBOSOMAL_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8 10" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP43919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY28686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="133" mass="14556" checksum="2B52D471AE425CA0" modified="2017-04-12" version="1">MSNENGNSRRRETLLGDRPGSYAIARHVRMSPTKVRRVVDLVRGMDVKDALVALKFAPQAASEPVYKVVASAIANAESAEALRSDDLYISKAFVDEGVTLRRIRPRAKGSASRILKRGSHITVVVEPRETKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCV1</accession>
    <name>A0A1Q2CCV1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl-CoA hydratase 2</fullName>
            <ecNumber evidence="1">4.2.1.119</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Enoyl-CoA hydratase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_02810</name>
        <name evidence="7" type="ORF">SAMN05428934_101162</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a (3R)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:26526"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57319"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="EC" id="4.2.1.119"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="4.2.1.119" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY27042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02810"/>
    <dbReference type="EnsemblBacteria" id="AQP43875">
        <property type="protein sequence ID" value="AQP43875"/>
        <property type="gene ID" value="RPIT_02810"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY27042">
        <property type="protein sequence ID" value="SDY27042"/>
        <property type="gene ID" value="SAMN05428934_101162"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02810"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MaoC-like" evidence="5">
        <location>
            <begin position="12"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY27042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="135" mass="14386" checksum="FD03B9E967708F90" modified="2017-04-12" version="1">MTEAAPGQGLPELRVRVTRSTVVRYSGASTDFNEIHFSERHAQAIGLPGVVAHGMWTMGAGLRVVTDWIGDPARVLSYTVRFTRPVVVPDTDEGTEVVYTATVTDVVEGTAKISITASCDGEAVLGAARAEVRID</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD19</accession>
    <name>A0A1Q2CD19_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Octanoyltransferase</fullName>
            <ecNumber evidence="6 7">2.3.1.181</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lipoate-protein ligase B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoyl/octanoyl transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lipB</name>
        <name evidence="12" type="ORF">RPIT_03570</name>
        <name evidence="13" type="ORF">SAMN05428934_101315</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6 7">Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>L-lysyl-[protein] + octanoyl-[ACP] = H(+) + holo-[ACP] + N(6)-octanoyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9636"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78463"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="EC" id="2.3.1.181"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6 7">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="6">In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the LipB family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.181" evidence="6 7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY31779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03570"/>
    <dbReference type="EnsemblBacteria" id="AQP44004">
        <property type="protein sequence ID" value="AQP44004"/>
        <property type="gene ID" value="RPIT_03570"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY31779">
        <property type="protein sequence ID" value="SDY31779"/>
        <property type="gene ID" value="SAMN05428934_101315"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03570"/>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00592"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033819">
        <property type="term" value="F:lipoyl(octanoyl) transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16444">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00013">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000544">
        <property type="entry name" value="Octanoyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020605">
        <property type="entry name" value="Octanoyltransferase_CS"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016262">
        <property type="entry name" value="LPLase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00214">
        <property type="entry name" value="lipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01313">
        <property type="entry name" value="LIPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0436">Ligase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="11">
        <location>
            <begin position="32"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="70"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="142"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="155"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="6 8">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="6 10">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR016262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP44004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY31779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="219" mass="23513" checksum="6AAABB7260A19F31" modified="2017-04-12" version="1">MLTFEYLTASGPLDYYQVWDHQRAVHATVADATRPGHVILVEHAPVYTAGRRTKLSDYPKDGTPVVPVDRGGEITYHGPGQLVGYPIVPLRDGVGVVDYVRALEGAVIDLLEGYGLSAGRVPGRTGVWLPAEGERPERKICAIGVRVARRTTMHGFALNVLSSAERFCNIVPCGIADAGVTSLVEELAWPWSVSAVAEALEPHLRRALEMVSSGGVSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD60</accession>
    <name>A0A1Q2CD60_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44062">
        <property type="protein sequence ID" value="AQP44062"/>
        <property type="gene ID" value="RPIT_03890"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03890"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="265" mass="28995" checksum="1561593EAB059773" modified="2017-04-12" version="1">MNRLSACLRQYYPAALPLLDDKFDRRDVWAVLAKAPDPGSGRKLTHAQTVTTLKRAGRKRYLDHTAAKILDVLHSDQLAAPPQQSRALAVRTVTLIRILQATRAEIESVEAEMAAAFEQHPDAEIYLSLPGKGHVIGARVLGEFGDDPDRYEDVKARRNYAGTSPLTIASGRQRIVKARHVRPRDWPTPWTGGPSVACRAALGRWTITTRRQLPVTSIMKPSGPSPTDSRASSTAASKHAPSTTRTPPGNTDTSLPLDTLDTWGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD80</accession>
    <name>A0A1Q2CD80_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13 14">UDP-N-acetylmuramoylalanine--D-glutamate ligase</fullName>
            <ecNumber evidence="5 13 14">6.3.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">D-glutamic acid-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">murD</name>
        <name evidence="18" type="ORF">RPIT_04020</name>
        <name evidence="19" type="ORF">SAMN05428934_101407</name>
    </gene>
    <organism evidence="18 20">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 20" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">RP1T</strain>
        </source>
    </reference>
    <reference evidence="19 21" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 21">RP1</strain>
        </source>
    </reference>
    <reference evidence="18" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 14">
            <text>ATP + D-glutamate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16429"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29986"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 13 14">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the MurCDEF family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.9" evidence="5 13 14"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY34285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04020"/>
    <dbReference type="EnsemblBacteria" id="AQP44082">
        <property type="protein sequence ID" value="AQP44082"/>
        <property type="gene ID" value="RPIT_04020"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY34285">
        <property type="protein sequence ID" value="SDY34285"/>
        <property type="gene ID" value="SAMN05428934_101407"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04020"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008764">
        <property type="term" value="F:UDP-N-acetylmuramoylalanine-D-glutamate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00639">
        <property type="entry name" value="MurD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005762">
        <property type="entry name" value="MurD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01262">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01087">
        <property type="entry name" value="murD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01011">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 13 14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8 13 14" id="KW-0132">Cell division</keyword>
    <keyword evidence="9 13 14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="12 13 14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13 18" id="KW-0436">Ligase</keyword>
    <keyword evidence="13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 13 14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlaDh_PNT_C" evidence="15">
        <location>
            <begin position="21"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="17">
        <location>
            <begin position="133"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="16">
        <location>
            <begin position="343"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="135"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="AQP44082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="SDY34285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="487" mass="51873" checksum="D7E522B36CECC783" modified="2017-04-12" version="1">MGGRPVTGEWIRSANRLSDWSRAQVVVAGLGVSGFAAADGLMSLGAKVTVLDESESHADKATLLETLDVTVRLGRGATAELPPGTDLVVTSPGWRPSAPLLKQAAAAGVPVWGETELAWRMMQPDRSIPWLAVTGTNGKTTTTQMLESMLIADGRKAAAVGNIGRPIIEAILDDVDYDVFAVELSSFQLHWMNNVNLHSAVVLNVHADHLEWYAGDDGMQRYTDDKAKIYQGVTHSCVYNVDEPVTERMVEDAEVVEGARAIGFTLGTPAISMLGIVDDLIVDRAFVEQRRDSALELAKISDVQPFAPHNVANALAAAALARSYGVRAPSVAAGLQRLQLAGHRIQKVAESGGVAWVDDSKATNPHAANSAMQAFDSFVWIAGGQAKGTTFDELISSHRSKMRGAVVIGVDRHLIAETLARHAPDLPVRVLDSTDTGVMDEVVALAGAMARPGDTVLLSPGCASLDMFDSYSDRGDAFAQAVARYLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD86</accession>
    <name>A0A1Q2CD86_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycerate kinase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_03625</name>
        <name evidence="5" type="ORF">SAMN05428934_101326</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycerate kinase type-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY32134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03625"/>
    <dbReference type="EnsemblBacteria" id="AQP44015">
        <property type="protein sequence ID" value="AQP44015"/>
        <property type="gene ID" value="RPIT_03625"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY32134">
        <property type="protein sequence ID" value="SDY32134"/>
        <property type="gene ID" value="SAMN05428934_101326"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03625"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008887">
        <property type="term" value="F:glycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031388">
        <property type="term" value="P:organic acid phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018193">
        <property type="entry name" value="Glyc_kinase_flavodox-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004381">
        <property type="entry name" value="Glycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018197">
        <property type="entry name" value="Glycerate_kinase_RE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036129">
        <property type="entry name" value="Glycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02595">
        <property type="entry name" value="Gly_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110738">
        <property type="entry name" value="SSF110738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY32134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="294" mass="30030" checksum="17D343B8F2B81873" modified="2017-04-12" version="1">MRVVITADAVAGLSPAAASALIARAFSDRGAQVAVVPLGVSGEPLREALEALAPRTDVVRPDDAAALRQVLQSDRSPLVDLTGTAAPELQGLAAALGTDPGVALEDARERWSDRDLVALVPEEEVALPLVGLNGLAATQGRRAGDDLSTVLARDAEAERWASSLGLDPTLPGAGAAGGLGLIVQALGGRMTDPLTYLADVAGLADTMGAADLVVTAAESLDFHAVGGPIVKRAVAMAGAALRPAIAIVGRNFVSARELRLAGFEEAYPLGAAGEEPTPERLSEVAMRVATTWSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDD9</accession>
    <name>A0A1Q2CDD9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protoheme IX farnesyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.141</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Heme B farnesyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Heme O synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ctaB</name>
        <name evidence="8" type="ORF">RPIT_04300</name>
        <name evidence="9" type="ORF">SAMN05428934_101465</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(2E,6E)-farnesyl diphosphate + H2O + heme b = diphosphate + Fe(II)-heme o</text>
            <dbReference type="Rhea" id="RHEA:28070"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:60530"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.141"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Porphyrin-containing compound metabolism; heme O biosynthesis; heme O from protoheme: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.141" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY36027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04300"/>
    <dbReference type="EnsemblBacteria" id="AQP44129">
        <property type="protein sequence ID" value="AQP44129"/>
        <property type="gene ID" value="RPIT_04300"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY36027">
        <property type="protein sequence ID" value="SDY36027"/>
        <property type="gene ID" value="SAMN05428934_101465"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04300"/>
    <dbReference type="UniPathway" id="UPA00834">
        <property type="reaction ID" value="UER00712"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008495">
        <property type="term" value="F:protoheme IX farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048034">
        <property type="term" value="P:heme O biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13957">
        <property type="entry name" value="PT_UbiA_Cox10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00154">
        <property type="entry name" value="CyoE_CtaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006369">
        <property type="entry name" value="Protohaem_IX_farnesylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43448">
        <property type="entry name" value="PTHR43448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01473">
        <property type="entry name" value="cyoE_ctaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY36027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="306" mass="33728" checksum="89B41E103F91CBCF" modified="2017-04-12" version="1">MAVQSAAASAEVRLVDVIKAYVALTKPRIIELLLVTTAPAMFLAAGGLPPWELILFTMVGGLFAAASANTFNCVLDADIDEVMRRTRRRPMPRHQVSSRNATIFGFVLGIIATLILGLGTNWLSAFLAMTANAFYVFVYTMLLKRRTWQNIVWGGIAGCFPPLVGWTAVTGSIDWPPLILFAIVFLWTPPHTWALAFRYKDDYAAAQVPMLPVVRSAPRVATQIFWYTLATVVVSLLLWPVTPTGPLYPIAAAAFGLVFLYEAAQLWRRAHAGAEGAQLKAMRLFHWSNTYLALLFLAVAIDPLIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDF8</accession>
    <name>A0A1Q2CDF8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_04310</name>
        <name evidence="2" type="ORF">SAMN05428934_101467</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY36081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44131">
        <property type="protein sequence ID" value="AQP44131"/>
        <property type="gene ID" value="RPIT_04310"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY36081">
        <property type="protein sequence ID" value="SDY36081"/>
        <property type="gene ID" value="SAMN05428934_101467"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04310"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007061">
        <property type="entry name" value="DUF664"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04978">
        <property type="entry name" value="DUF664"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY36081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="189" mass="20727" checksum="3EF2C89D1EBD3AA7" modified="2017-04-12" version="1">MDLKETLLRQLQFNRDALLWKCEGLSERDLRLPRTPTGTNLLGLVKHCAWVEHEYFITSFGRSSGLNPPDIDYDADPNGDLAATESEAAAELLSTYREVASHVDAAIAEQTLDTPGHVSWWGERGDTTLGDVLVHVLGDIARHAGHADIIREGIDGLAGLRGDNTNLWVPEGGWDTRVLRLTAIAESFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDJ3</accession>
    <name>A0A1Q2CDJ3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyltransferase (GNAT) family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04655</name>
        <name evidence="3" type="ORF">SAMN05428934_101538</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04655"/>
    <dbReference type="EnsemblBacteria" id="AQP44193">
        <property type="protein sequence ID" value="AQP44193"/>
        <property type="gene ID" value="RPIT_04655"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37799">
        <property type="protein sequence ID" value="SDY37799"/>
        <property type="gene ID" value="SAMN05428934_101538"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04655"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY37799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="178" mass="18842" checksum="4F71FCE716F37393" modified="2017-04-12" version="1">MSAIDTVRLALPAEAVDIARIQRRVWSDSGLLSAAAESFSADEATRAWHDAIVKPALAHQRVLVAIAEAGVVGFAVTGPSADPDQQERVGQIAEFVVDPRHRGAGHGSRLINAAVDTLRQDGYLVATMWLPTTNDSLRAFLSSCGWGPDGAHQEVGAQDGGTTLKLIRLHTDISTPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDY8</accession>
    <name>A0A1Q2CDY8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA-dihydrouridine synthase</fullName>
            <ecNumber evidence="5">1.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_05085</name>
        <name evidence="9" type="ORF">SAMN05428934_101623</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 5,6-dihydrouridine in tRNA + NAD(+) = a uridine in tRNA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:54452"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 5,6-dihydrouridine in tRNA + NADP(+) = a uridine in tRNA + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:23624"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the dus family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY39990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05085"/>
    <dbReference type="EnsemblBacteria" id="AQP44265">
        <property type="protein sequence ID" value="AQP44265"/>
        <property type="gene ID" value="RPIT_05085"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY39990">
        <property type="protein sequence ID" value="SDY39990"/>
        <property type="gene ID" value="SAMN05428934_101623"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05085"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024036">
        <property type="entry name" value="tRNA-dHydroUridine_Synthase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004652">
        <property type="entry name" value="tRNA_dU_NifR3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00737">
        <property type="entry name" value="nifR3_yhdG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Dus" evidence="7">
        <location>
            <begin position="26"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY39990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="383" mass="41419" checksum="C3C7F7079078DC05" modified="2017-04-12" version="1">MPTIEPLRLHAPSRRDAVVVELPVVLAPMAGVTNAAYRQLCREQGAGLYVCEMITSRGLVVGDPKTRAMLAFDPGEATRSVQLYGVDADVMADAARILITEHQVDHIDLNFGCPVPKVTRKGGGGVLPYKRDRLRAIVRETVRAADEFGVPVTIKTRIGIDDAHVTFLDAGRIAQEEGAAAIALHGRTVQQAYSGEADWSRIAELVEEVDIPVLGNGDIWEAEDALRMMDETGCAGVVIGRGCLGRPWLFGDLAAAMHGEPLRHRPTLGEVGAMIVRHAELLSGIMGERHGLTDLRKHMAWYFKGYPVGELRRHFAMVSSMAELLALVEQLDADAEFPVGELGTPRGRQGSPRGKVVLPYGWYDDTSGSDLDLSEAEIGVSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE49</accession>
    <name>A0A1Q2CE49_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized conserved protein YlxW, UPF0749 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05725</name>
        <name evidence="4" type="ORF">SAMN05428934_10392</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0749 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05725"/>
    <dbReference type="EnsemblBacteria" id="AQP44371">
        <property type="protein sequence ID" value="AQP44371"/>
        <property type="gene ID" value="RPIT_05725"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67459">
        <property type="protein sequence ID" value="SDY67459"/>
        <property type="gene ID" value="SAMN05428934_10392"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05725"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010273">
        <property type="entry name" value="DUF881"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37313">
        <property type="entry name" value="PTHR37313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05949">
        <property type="entry name" value="DUF881"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY67459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="250" mass="26944" checksum="6984C6A55F13CE62" modified="2017-04-12" version="1">MPDQDTPRRASEQPQRSLLRDFLRPSKGQAVVGLVLFLTALSVVLTLRAQSAQPEFTNVRQADLIQLLDNVTSETRRLEDEVRELELARTELLSGADRDQAAREEAARRLEQAQIIAGTVPVAGPGVRIEIADPEGRISAELLLDAVEELRDAGAEVIEVNDAVRLVMGSWFGTDDTGAITVDGVVISAPYVLEAIGDAATLEAGARFRGGLVSEVEGERVGGSVTIEQLPEIAVDTVVSPEVNEFARPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE96</accession>
    <name>A0A1Q2CE96_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MerR HTH family regulatory protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05745</name>
        <name evidence="4" type="ORF">SAMN05428934_10396</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05745"/>
    <dbReference type="EnsemblBacteria" id="AQP44375">
        <property type="protein sequence ID" value="AQP44375"/>
        <property type="gene ID" value="RPIT_05745"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67577">
        <property type="protein sequence ID" value="SDY67577"/>
        <property type="gene ID" value="SAMN05428934_10396"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05745"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="2">
        <location>
            <begin position="35"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY67577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="183" mass="20325" checksum="433CFF05F78E8417" modified="2017-04-12" version="1">MIEKPEVLQDLLFDGEFTPVPSDTGYRGPIAHRVAGITYRQLDYWARTGLVVPSIRNAEGSGTQRLYSFRDILLLRVVKRFLDVGISLQQIRVAIDHLRARGIDDLTELTLVSDGFSVYEVTSANELFDLSRGGQGMFMISVSSVWRELEGTLASLPGERTADEAPAEDPSDELAARRRARVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE97</accession>
    <name>A0A1Q2CE97_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_06010</name>
        <name evidence="7" type="ORF">SAMN05428934_103148</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06010"/>
    <dbReference type="EnsemblBacteria" id="AQP44421">
        <property type="protein sequence ID" value="AQP44421"/>
        <property type="gene ID" value="RPIT_06010"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68922">
        <property type="protein sequence ID" value="SDY68922"/>
        <property type="gene ID" value="SAMN05428934_103148"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06010"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:cellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008217">
        <property type="entry name" value="Ccc1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31851">
        <property type="entry name" value="PTHR31851"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01988">
        <property type="entry name" value="VIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY68922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="236" mass="23914" checksum="83A0DAEBCC589F27" modified="2017-04-12" version="1">MSTVVEPQIESAALSGRLNWLRAGVLGANDGIVSISATVVGVAAATNTVTPVLLAGVAAVVAGAISMALGEYVSVSSAADSQRSIIATLRRLLTSDRPLADGALVAAYERQGLSRDTAERVVAEIGEHNVMRAHLSQRYHLAEDEVVNAWHAAIASGISFLAGALLPFLTIILTPVPLRIPVTVVAVLVALALTGGLGAKLGGAPVRPAMVRVMAGGMLALAATYAIGLALGVSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEB8</accession>
    <name>A0A1Q2CEB8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein-export membrane protein SecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secF</name>
        <name evidence="11" type="ORF">RPIT_06305</name>
        <name evidence="12" type="ORF">SAMN05428934_103206</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06305"/>
    <dbReference type="EnsemblBacteria" id="AQP44472">
        <property type="protein sequence ID" value="AQP44472"/>
        <property type="gene ID" value="RPIT_06305"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70412">
        <property type="protein sequence ID" value="SDY70412"/>
        <property type="gene ID" value="SAMN05428934_103206"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06305"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01464_B">
        <property type="entry name" value="SecF_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022646">
        <property type="entry name" value="SecD/SecF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005665">
        <property type="entry name" value="SecF_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07549">
        <property type="entry name" value="Sec_GG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01755">
        <property type="entry name" value="SECFTRNLCASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00916">
        <property type="entry name" value="2A0604s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00966">
        <property type="entry name" value="3a0501s07"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="279"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="323"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY70412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="377" mass="40893" checksum="3FF360D90A7D3D40" modified="2017-04-12" version="1">MSTTKRSIAERLYTGQLSYDFIKNRKLWFIISAVLLSASLLLILVRGLTLGIEFRGGTDFQAPMQVQSTTVDDVRAQVGDFEIEDLDAQVFAVGDDAIRVQTRSLNPEETTTTRADIGELAGVAPEEVTYNAIGPSWGEQISRQGLVALVVFLVAVMLLIAAYFRDWKMSIAAIVAVFHDLIITVGVYALVGFTVTPATVIGVLTILGYSLYDTVVVFDKIRENVKGIGHTNKTYSQQANYAVNQVIVRSINTTIIGVLPVLALFIAGATLQSGPLADLGLALLVGMIAGAYSSLFIAAPLLAWLREREPRMIEHREQIARRAARAEQKHARSAAKAEPAFAAAGSPAAPPTTEPTGPVVRNQRRTASTRAERRGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEC9</accession>
    <name>A0A1Q2CEC9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative pre-16S rRNA nuclease</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_06230</name>
        <name evidence="5" type="ORF">SAMN05428934_103191</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YqgF HJR family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06230"/>
    <dbReference type="EnsemblBacteria" id="AQP44458">
        <property type="protein sequence ID" value="AQP44458"/>
        <property type="gene ID" value="RPIT_06230"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70018">
        <property type="protein sequence ID" value="SDY70018"/>
        <property type="gene ID" value="SAMN05428934_103191"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06230"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000967">
        <property type="term" value="P:rRNA 5'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16964">
        <property type="entry name" value="YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00651">
        <property type="entry name" value="Nuclease_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005227">
        <property type="entry name" value="YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33317">
        <property type="entry name" value="PTHR33317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03652">
        <property type="entry name" value="RuvX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00250">
        <property type="entry name" value="RNAse_H_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="YqgFc" evidence="3">
        <location>
            <begin position="4"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY70018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="155" mass="16295" checksum="A94786FED84EAB9D" modified="2017-04-12" version="1">MADGVRLGVDWGKARIGVAACNAGTTFAYPVETVPAGRDEMRSLTAIVKEYAPDIVYVGLPLTLAGERGIAAGQVTARAAALATAIAPVEVRLIDERMSTASASRSLGDAGRRSRQQRRVIDQAAAVEILQRAIDAEARENAPVGEPVPAKEEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CED4</accession>
    <name>A0A1Q2CED4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Bcr/CflA family efflux transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_06255</name>
        <name evidence="10" type="ORF">SAMN05428934_103196</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Bcr/CmlA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44463">
        <property type="protein sequence ID" value="AQP44463"/>
        <property type="gene ID" value="RPIT_06255"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70151">
        <property type="protein sequence ID" value="SDY70151"/>
        <property type="gene ID" value="SAMN05428934_103196"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06255"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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    </dbReference>
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        <property type="entry name" value="efflux_Bcr_CflA"/>
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    </dbReference>
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    </dbReference>
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            <begin position="51"/>
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            <begin position="83"/>
            <end position="105"/>
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        <location>
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            <end position="132"/>
        </location>
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        <location>
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            <end position="335"/>
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            <begin position="13"/>
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        </location>
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        <source>
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        <source>
            <dbReference type="RuleBase" id="RU365088"/>
        </source>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP44463.1"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY70151.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="407" mass="42419" checksum="9D790071D1865C6A" modified="2017-04-12" version="1">MEHLGNRYSRRRRIAIIVTLGLLTGLGPFTIDLYLPAFPALKSDLGINDAQVQLTLSATTLGFAVGQLVVGPLSDRVGRRLPLVAMTLLHVVASVLVAVAPSLVFLTAMRALQGIGAAGGAVVAMAMARDLFGGKPLVIMLSRLALISGLAPIVAPIVGSWMVLVMDWRGIFWGLAVYGVGVVLLVVTLTVETRPASERAPAGRGRLRAAYRHVVGDRLYVGVLLVSAFSFGGLLSYVSSSSVLLQEVYGLTPRGFGAVFAICSVGVFVGVQAGGRLAARYGPHRVLAYSTALLVVGSLGVLLVYAASLPYRALVPAFFSYTLAFGLGAPCVSVLGLQHHRENSGVAASLLGASNQVVGSVVGPLIGVFHVTSALPVGAVMLACAVLAVAMLWLVVRPHRLGDEVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEE9</accession>
    <name>A0A1Q2CEE9_9ACTN</name>
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        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="4" type="ORF">RPIT_06450</name>
        <name evidence="5" type="ORF">SAMN05428934_103235</name>
    </gene>
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
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            <taxon>Bacteria</taxon>
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    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
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        </location>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY71190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="130" mass="13006" checksum="7EE9239A28DEFE90" modified="2017-04-12" version="1">MTGRWAVTLLAALAGVVAGATAQAAGSPVASLAWALLAGVGLSLMLRGGGLRVLGVLLTVLATASAGWAVQARVWPSAAGFAVVALASVGITVAGPRWAGRSRAAVDRPRDLWQSMDAGEDPTAEHGVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEJ8</accession>
    <name>A0A1Q2CEJ8_9ACTN</name>
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        <submittedName>
            <fullName evidence="3">CHAT domain-containing protein</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">RPIT_06485</name>
        <name evidence="3" type="ORF">SAMN05428934_103242</name>
    </gene>
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY71382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06485"/>
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        <property type="protein sequence ID" value="AQP44500"/>
        <property type="gene ID" value="RPIT_06485"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71382">
        <property type="protein sequence ID" value="SDY71382"/>
        <property type="gene ID" value="SAMN05428934_103242"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="569"/>
            <end position="781"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY71382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="803" mass="84235" checksum="B0F4D76512EBF97E" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEL0</accession>
    <name>A0A1Q2CEL0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Small ribosomal subunit biogenesis GTPase RsgA</fullName>
            <ecNumber evidence="3">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rsgA</name>
        <name evidence="7" type="ORF">RPIT_06820</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06820"/>
    <dbReference type="EnsemblBacteria" id="AQP44559">
        <property type="protein sequence ID" value="AQP44559"/>
        <property type="gene ID" value="RPIT_06820"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06820"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="P:ribosomal small subunit biogenesis"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RsgA_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
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    <feature type="domain" description="CP-type G" evidence="6">
        <location>
            <begin position="114"/>
            <end position="267"/>
        </location>
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            <end position="22"/>
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        <ligand>
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        <location>
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            <dbReference type="ARBA" id="ARBA00023134"/>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="AQP44559.1"/>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="331" mass="35813" checksum="B777650421512773" modified="2017-04-12" version="1">MARVGDAVKSLREDDHSGFDRPRRRSRPRTKERPDYSSLPTARIISVDRGRYRCVLPDGSPVTAVRGRLIDRKGVIVGDVVTLDGDVSGAEGTLSRIVDVAERRTVLRRSADDADTFERPIVANADQLFIVTALADPPPRMGMIDRILVAAFDAQIDPVLCLTKADLASPDELRAAYEPLGVPIVVTDPEADLTEIRATLNDRVTVFVGHSGVGKSTLVNRLIPDAHRATAEVSDLTGKGRHTSTSAIAMELPDGGWIIDTPGVRSFGISHVRTSSILGAFPDLSEFADECPRGCHHETGAIECALDDAVADGRLSEERLASFRRMGRAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEM7</accession>
    <name>A0A1Q2CEM7_9ACTN</name>
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    </protein>
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        <name evidence="8" type="ORF">SAMN05428934_11084</name>
    </gene>
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
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                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
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        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
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            <end position="185"/>
        </location>
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    </evidence>
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    </evidence>
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            <dbReference type="EMBL" id="AQP44558.1"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDZ09759.1"/>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="204" mass="21382" checksum="690778B1B15A0EEC" modified="2017-04-12" version="1">MSLTRFLSRSLFASYFIAEGVKAVTKPAETAPDAEAFTSRVAPLVQRVVPADIASYVPERAETWVRISGVAQVLGGVMFATGIGRRLGAMLLAKASVLNVAIALPDKGASQDAKQAARPAVLRNAALLGASMLAAQDTQGKPSLAWRTEHAAKVTEKKAAALGDDVSKAARKASAKAEKQAKSLGKKARKSTKQLTRKLEAAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEN8</accession>
    <name>A0A1Q2CEN8_9ACTN</name>
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        <recommendedName>
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    </gene>
    <organism evidence="7 9">
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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            </authorList>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the UPF0182 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ09463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06895"/>
    <dbReference type="EnsemblBacteria" id="AQP44573">
        <property type="protein sequence ID" value="AQP44573"/>
        <property type="gene ID" value="RPIT_06895"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09463">
        <property type="protein sequence ID" value="SDZ09463"/>
        <property type="gene ID" value="SAMN05428934_11067"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06895"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01600">
        <property type="entry name" value="UPF0182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005372">
        <property type="entry name" value="UPF0182"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39344">
        <property type="entry name" value="PTHR39344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03699">
        <property type="entry name" value="UPF0182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-1003">Cell membrane</keyword>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="83"/>
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        <location>
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            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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            <begin position="215"/>
            <end position="237"/>
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            <end position="307"/>
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    </feature>
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        <location>
            <begin position="882"/>
            <end position="901"/>
        </location>
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        <source>
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            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022989"/>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP44573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ09463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="957" mass="105083" checksum="A021F80B7D707DA4" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEQ8</accession>
    <name>A0A1Q2CEQ8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">1,3-beta-galactosyl-N-acetylhexosamine phosphorylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_07005</name>
        <name evidence="4" type="ORF">SAMN05428934_11044</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07005"/>
    <dbReference type="EnsemblBacteria" id="AQP44593">
        <property type="protein sequence ID" value="AQP44593"/>
        <property type="gene ID" value="RPIT_07005"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08923">
        <property type="protein sequence ID" value="SDZ08923"/>
        <property type="gene ID" value="SAMN05428934_11044"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07005"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035356">
        <property type="entry name" value="LBP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035363">
        <property type="entry name" value="LBP_M"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17386">
        <property type="entry name" value="LBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17385">
        <property type="entry name" value="LBP_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LBP_M" evidence="1">
        <location>
            <begin position="2"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="LBP_C" evidence="2">
        <location>
            <begin position="36"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ08923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="99" mass="10736" checksum="220FA9CEF01C524F" modified="2017-04-12" version="1">MALYIAGLPYSADNARLLHRAIYWAAGREEGFDGHWNSSNPAVEVAVFPEAGKAFVMNTTTEPVTTTVRGRAAGLVSEGEVRELQFDLAPAQSQWVDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CES5</accession>
    <name>A0A1Q2CES5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Regulatory protein RecX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">recX</name>
        <name evidence="5" type="ORF">RPIT_07080</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Modulates RecA activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the RecX family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07080"/>
    <dbReference type="EnsemblBacteria" id="AQP44606">
        <property type="protein sequence ID" value="AQP44606"/>
        <property type="gene ID" value="RPIT_07080"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07080"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006282">
        <property type="term" value="P:regulation of DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01114">
        <property type="entry name" value="RecX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003783">
        <property type="entry name" value="Regulatory_RecX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33602">
        <property type="entry name" value="PTHR33602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02631">
        <property type="entry name" value="RecX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="167" mass="17813" checksum="B6B4607644F55149" modified="2017-04-12" version="1">MTSEQGDQLEVARKIALDLLAVRQRSAHELGAAMARRNVPDDVAGEIIARFTGVGLVDDEAFAAALTSTRSTVGQRGRHRIRAELQAKGIDREVAESALADLDPDDELEAALALARRRARSMTSLEPHVARRRLAGVLARRGFPSSVVSAAVSEALGGSVEFSTGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF49</accession>
    <name>A0A1Q2CF49_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peroxiredoxin</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Predicted peroxiredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07620</name>
        <name evidence="2" type="ORF">SAMN05428934_1215</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000021">
        <property type="protein sequence ID" value="SDZ22666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07620"/>
    <dbReference type="EnsemblBacteria" id="AQP44690">
        <property type="protein sequence ID" value="AQP44690"/>
        <property type="gene ID" value="RPIT_07620"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ22666">
        <property type="protein sequence ID" value="SDZ22666"/>
        <property type="gene ID" value="SAMN05428934_1215"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07620"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027396">
        <property type="entry name" value="DsrEFH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003787">
        <property type="entry name" value="Sulphur_relay_DsrE/F-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02635">
        <property type="entry name" value="DrsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75169">
        <property type="entry name" value="SSF75169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ22666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="119" mass="12332" checksum="8A7981FECC3A03CC" modified="2017-04-12" version="1">MNKAAISLTTGLEDAEKVTVAFLVAVGAAEAGRETLMFLTKEAVRLAVSGFARATACEGCPPLTDLMDRYAAAGGRYIACGVCVKAKAIDAGTLLPNAEVAGTVQLWEWIGEGATTFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF65</accession>
    <name>A0A1Q2CF65_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HIT family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Histidine triad (HIT) family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_07980</name>
        <name evidence="4" type="ORF">SAMN05428934_11336</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44751">
        <property type="protein sequence ID" value="AQP44751"/>
        <property type="gene ID" value="RPIT_07980"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16683">
        <property type="protein sequence ID" value="SDZ16683"/>
        <property type="gene ID" value="SAMN05428934_11336"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07980"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01277">
        <property type="entry name" value="HINT_subgroup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039384">
        <property type="entry name" value="HINT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23089">
        <property type="entry name" value="PTHR23089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="4"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="1">
        <location>
            <begin position="95"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ16683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="130" mass="13981" checksum="5B802E3BACDB78BF" modified="2017-04-12" version="1">MDCLFCKIAAGEIPSKKVYEDEVAFAFLDISPWQEGHTLVVPKRHIADVLADDDVLAEIAPAVARVGRLLIDKLGADACNVVSNAGAASGQEVFHAHVHVLPRWASNPGVGNMKAEVIADLDDVREKIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF78</accession>
    <name>A0A1Q2CF78_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutamyl-Q tRNA(Asp) synthetase</fullName>
            <shortName evidence="5">Glu-Q-RSs</shortName>
            <ecNumber evidence="5">6.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">gluQ</name>
        <name evidence="8" type="ORF">RPIT_08020</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08020"/>
    <dbReference type="EnsemblBacteria" id="AQP44758">
        <property type="protein sequence ID" value="AQP44758"/>
        <property type="gene ID" value="RPIT_08020"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08020"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01428">
        <property type="entry name" value="Glu_Q_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022380">
        <property type="entry name" value="Glu-Q_tRNA(Asp)_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="7">
        <location>
            <begin position="5"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glutamate binding" evidence="5">
        <location>
            <begin position="5"/>
            <end position="9"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="5">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="5">
        <location>
            <begin position="232"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="300" mass="32679" checksum="8630960870C32842" modified="2017-04-12" version="1">MHVDRYAPSPTSDLHLGNLRTALAGWLLARHAGGEWLMRVEDLDRARVRAAGDAERRQLDDLSSLGLHWDGPVARQSERLELYADAVARLDTYECFCTRREIAEASSAPHDGYRAYPGTCRRLSDRQRSELRGSRRPAIRVHAGGATFAVEDATAGRVEGVVDDFVLVRGDGEFAYNLAVVVDDIDMGVTHITRGDDLLSSAPRQAWLTAQLGGSRARYAHVGLVLGPDGRRLAKRDGAVTLRDLPDLSPGDVLATLSESLGLGPCRTTYEALAAMPGDGRFYASATWTDGTLTSPRRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFD3</accession>
    <name>A0A1Q2CFD3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Tryptophan synthase beta chain</fullName>
            <ecNumber evidence="11">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">trpB</name>
        <name evidence="13" type="ORF">RPIT_08490</name>
        <name evidence="14" type="ORF">SAMN05428934_1079</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 11">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the TrpB family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY96329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08490"/>
    <dbReference type="EnsemblBacteria" id="AQP44826">
        <property type="protein sequence ID" value="AQP44826"/>
        <property type="gene ID" value="RPIT_08490"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY96329">
        <property type="protein sequence ID" value="SDY96329"/>
        <property type="gene ID" value="SAMN05428934_1079"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08490"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06446">
        <property type="entry name" value="Trp-synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00133">
        <property type="entry name" value="Trp_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006653">
        <property type="entry name" value="Trp_synth_b_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006654">
        <property type="entry name" value="Trp_synth_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023026">
        <property type="entry name" value="Trp_synth_beta/beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001413">
        <property type="entry name" value="Trp_syn_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00263">
        <property type="entry name" value="trpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00168">
        <property type="entry name" value="TRP_SYNTHASE_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="PALP" evidence="12">
        <location>
            <begin position="57"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="11">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP44826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY96329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="404" mass="42837" checksum="6378D66682C7C49F" modified="2017-04-12" version="1">MSSLIHADDQGFFGDHGGRFVPPQLEAPIAEVAEAYAEARDDPEFLAEYEALLTDYVGRPSPLFFAKRLTAELGGARIYLKREDLNHTGAHKINHCLGEALLAKRMGKRKLIAETGAGQHGVALATAAALLGLECEIHMGAIDVAKQHPNVVRMELLGAKVVAVEEGGRSLKEAVDSAFAVFASDYADTFFAIGSVVGPHPYPTMVRDFQSVVGREARQQCLDKIGRLPDALIAAVGGGSNALGLFTAFLEDDSVAIYGVEPGGRSLDVVGEHAATMTLGREGTLHGMKTLVLQDADGEPSPVHSIASGLDYPGIGPQHAHLRDVGRVEYVTASDQDTLDAFQLLCRTEGIIPALESCHAVAHAMKLAPTLDAEQVIIVNLSGRGDKDIDYVAERLGVGTGSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFF4</accession>
    <name>A0A1Q2CFF4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Pro-Hyp dipeptidase. Metallo peptidase. MEROPS family M38</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08615</name>
        <name evidence="3" type="ORF">SAMN05428934_10734</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY96920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08615"/>
    <dbReference type="EnsemblBacteria" id="AQP44844">
        <property type="protein sequence ID" value="AQP44844"/>
        <property type="gene ID" value="RPIT_08615"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY96920">
        <property type="protein sequence ID" value="SDY96920"/>
        <property type="gene ID" value="SAMN05428934_10734"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08615"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="42"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY96920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="358" mass="38380" checksum="28B24584661AE248" modified="2017-04-12" version="1">MTAFRIDGVILPDGERGEFFVADGVVADGPVRDAETIAEGCWVIPGLVDAHCHIGLGAEGDVGRERAREQALTDLAAGTMLIRDAGSPSDTRWVHDAADLPRLVRSGQHVARPKRYIRNLGVEVEPDRLVEQVRAEARSGDGWVKLVGDWIDRSVGDLAPLWPADVAADAIAAAHDEGARVTAHCFGEQSVAELVAAGIDCIEHGTGMSDEVIEQMATRGTSLVPTMINLDRFPIYAEPAKEKFPAYFTHMMDLHARRRQTIGAAMEAGISIYTGTDAGTVVAHGRIRDEVDALAEIGGAEFALGAASWRARPWLGADVLTPGASADLIVLDADPRVDLSTLRRPIAMLLRGHPVAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFG7</accession>
    <name>A0A1Q2CFG7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_08390</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44810">
        <property type="protein sequence ID" value="AQP44810"/>
        <property type="gene ID" value="RPIT_08390"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08390"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025831">
        <property type="entry name" value="RecG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038475">
        <property type="entry name" value="RecG_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007421">
        <property type="entry name" value="Schlafen_AlbA_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038461">
        <property type="entry name" value="Schlafen_AlbA_2_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04326">
        <property type="entry name" value="AlbA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13749">
        <property type="entry name" value="HATPase_c_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlbA_2" evidence="2">
        <location>
            <begin position="19"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c_4" evidence="3">
        <location>
            <begin position="295"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="460" mass="51455" checksum="0B43D3AD2C6DDB60" modified="2017-04-12" version="1">MEITELTKEQVVSICATPEDHFHDCKSIRISPAKLTKAMSAFANADGGELIVGVEDDGAWGGFPTVEGANGHLQAMESLFPYGSEYSYEFFEHPTLGTFVLRVIIQKARQIKVASDGKAYVRRGAQSLPVADVEELRRRKGLSTHETATLNYPPEEITNSETIIGFMLEIVPETEPEKWLRKQTVIVDGHPTVAGTVLFHDEPQIHLPKSGVKLYRYTTSDDQGSREQLAYDPMSIEGPVIDLVYKTVEETVRQVEQIPLLEEGRGFTTIQYPRETLHEIITNALIHRDYEINDDVHVRIFENRIEVQSPGTLPAHITPNNILDERFSRNPMVVRLLNKFPDAPNKDVGEGLNTAFAAMRKLELKDPVITDTGTAVVVSIRHESLASPESRIVEYIKARGSINNREARTLLHRPEADRSIRRLFAKLEASGVIEKVPGTNKSGTRYRLMGSVSSDQESSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFH1</accession>
    <name>A0A1Q2CFH1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08715</name>
        <name evidence="3" type="ORF">SAMN05428934_10753</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44861">
        <property type="protein sequence ID" value="AQP44861"/>
        <property type="gene ID" value="RPIT_08715"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97357">
        <property type="protein sequence ID" value="SDY97357"/>
        <property type="gene ID" value="SAMN05428934_10753"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08715"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544467" evidence="1">
        <location>
            <begin position="27"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY97357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="139" mass="14972" checksum="B3FF1EB33DCC018D" modified="2017-04-12" version="1">MHLSRITIAGAIAAGIIVATAGSASAHHCYKNEWADAAYHHHRAGGTAWIPLSQMGRQFLIPEELQDVCGWAADKAVADFMKERNLTQEPLIHGKAVTGSGAYAKGKAPQPYSYLTDADFDLLGRALFGYLAECQEGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFJ4</accession>
    <name>A0A1Q2CFJ4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_08415</name>
        <name evidence="5" type="ORF">SAMN05428934_1207</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000020">
        <property type="protein sequence ID" value="SDZ22245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44815">
        <property type="protein sequence ID" value="AQP44815"/>
        <property type="gene ID" value="RPIT_08415"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ22245">
        <property type="protein sequence ID" value="SDZ22245"/>
        <property type="gene ID" value="SAMN05428934_1207"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08415"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544464" evidence="3">
        <location>
            <begin position="30"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ22245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="130" mass="13483" checksum="2A1E04EE9224258B" modified="2017-04-12" version="1">MPGLIKRIDRLPRLRLCCRPPVAPSGVAAAAGGGSMEVQVTWDPLAASASVGHYRVYRRKTAGQFYLLAVVTADALGTLVPGKLGIVDAPDYWPWPSGADPSAERCYAVSAVSTAGVEGPMSAEACASPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFK0</accession>
    <name>A0A1Q2CFK0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosome maturation factor RimM</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rimM</name>
        <name evidence="4" type="ORF">RPIT_08590</name>
        <name evidence="5" type="ORF">SAMN05428934_10729</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Binds ribosomal protein S19.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="2">The PRC barrel domain binds ribosomal protein S19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RimM family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY96804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08590"/>
    <dbReference type="EnsemblBacteria" id="AQP44840">
        <property type="protein sequence ID" value="AQP44840"/>
        <property type="gene ID" value="RPIT_08590"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY96804">
        <property type="protein sequence ID" value="SDY96804"/>
        <property type="gene ID" value="SAMN05428934_10729"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08590"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00014">
        <property type="entry name" value="Ribosome_mat_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011961">
        <property type="entry name" value="16S_RimM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002676">
        <property type="entry name" value="RimM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036976">
        <property type="entry name" value="RimM_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01782">
        <property type="entry name" value="RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02273">
        <property type="entry name" value="16S_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="RimM" evidence="3">
        <location>
            <begin position="9"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY96804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="174" mass="19092" checksum="0BDE55A816988EE5" modified="2017-04-12" version="1">MSDLVEVTIGRVGRAHGIRGDVFVDVRTDEPARRFRQGATVAVGEGRKPIELATVKWNRGKLIVSFTGFPDRTAVETLTGELLRVRVPADERPSEPEEYFDRQLVGLAVHDHADRRVGVIAEVLHLPAQDVLRVDTGADDDRLVPFVSALVPVVDLDAGLVRLADVVGLLEDQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFP9</accession>
    <name>A0A1Q2CFP9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09145</name>
        <name evidence="3" type="ORF">SAMN05428934_107142</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY99075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44933">
        <property type="protein sequence ID" value="AQP44933"/>
        <property type="gene ID" value="RPIT_09145"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY99075">
        <property type="protein sequence ID" value="SDY99075"/>
        <property type="gene ID" value="SAMN05428934_107142"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09145"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY99075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="255" mass="28770" checksum="FCA293A6F030BDE8" modified="2017-04-12" version="1">MTAKEDPVVQQHDSDDWRGEFQPAELAALRERIPTAIQRSQERSARAQAAYDDPDGDQDVYGAGMARGVQKELRTLLSDLPSYREAKIPTTRRMLTFVGNTLIFAQRVGKQMPRNFRRVRLSYLPDSRRELLSKTSNVKYSDPGLFDISDVLEGDQPASLEDALSHVELAVPRTTLFVPYYSSTPQGVGTIYFAPARLNGRYLEFADPERLTYERTPSSVDAPRTMLKPVAGFNSGDRPRTSVKLRQRRSEQEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFS4</accession>
    <name>A0A1Q2CFS4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein gp37</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_09355</name>
        <name evidence="2" type="ORF">SAMN05428934_102438</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY60788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09355"/>
    <dbReference type="EnsemblBacteria" id="AQP44966">
        <property type="protein sequence ID" value="AQP44966"/>
        <property type="gene ID" value="RPIT_09355"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY60788">
        <property type="protein sequence ID" value="SDY60788"/>
        <property type="gene ID" value="SAMN05428934_102438"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09355"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011101">
        <property type="entry name" value="DUF5131"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07505">
        <property type="entry name" value="DUF5131"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY60788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="248" mass="27930" checksum="D2BA7233F3F647CD" modified="2017-04-12" version="1">MKRKSGIEWTEVTWNPTTGCDRISDGCLNCYALTMAKRLKAMGSERYQNDGDPRTSGPGFALTLHPEALDQPYRWSGHRTVFVNSMSDLFHAKVPISFVRDVFQVIADTPQHTYQVLTKRSARLPKIADKLDWPSNLWMGVSVETSDFLYRVDHLREVPAAVRFLSCEPLLGSLAGIDLSGMGWVITGGESGPRARPLNPEWVREIRDACVEAQVPFFHKQWGGRTPKEQGRTLDGVVWDEMPRRAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFY8</accession>
    <name>A0A1Q2CFY8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Methionine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Methionyl-tRNA synthetase</fullName>
            <shortName evidence="9">MetRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">metG</name>
        <name evidence="13" type="ORF">RPIT_09730</name>
        <name evidence="14" type="ORF">SAMN05428934_102359</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met)</text>
            <dbReference type="Rhea" id="RHEA:13481"/>
            <dbReference type="Rhea" id="RHEA-COMP:9667"/>
            <dbReference type="Rhea" id="RHEA-COMP:9698"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY58637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09730"/>
    <dbReference type="EnsemblBacteria" id="AQP45031">
        <property type="protein sequence ID" value="AQP45031"/>
        <property type="gene ID" value="RPIT_09730"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY58637">
        <property type="protein sequence ID" value="SDY58637"/>
        <property type="gene ID" value="SAMN05428934_102359"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09730"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00098">
        <property type="entry name" value="Met_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023458">
        <property type="entry name" value="Met-tRNA_ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029038">
        <property type="entry name" value="MetRS_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45765">
        <property type="entry name" value="PTHR45765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57770">
        <property type="entry name" value="SSF57770"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-synt_1g" evidence="11">
        <location>
            <begin position="5"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_3" evidence="12">
        <location>
            <begin position="422"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="351"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF19303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP45031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY58637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="593" mass="65608" checksum="DB06E137A7AC9A2C" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFZ0</accession>
    <name>A0A1Q2CFZ0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ADP-ribose pyrophosphatase YjhB, NUDIX family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">DNA mismatch repair protein MutT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09680</name>
        <name evidence="4" type="ORF">SAMN05428934_102369</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY58921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09680"/>
    <dbReference type="EnsemblBacteria" id="AQP45023">
        <property type="protein sequence ID" value="AQP45023"/>
        <property type="gene ID" value="RPIT_09680"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY58921">
        <property type="protein sequence ID" value="SDY58921"/>
        <property type="gene ID" value="SAMN05428934_102369"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09680"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="19"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY58921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="171" mass="18848" checksum="B056FA2F5C0FB72A" modified="2017-04-12" version="1">MATPDFIVELRRSIGHAPLWLMGANALVLRGALPDAEVLLVRRSDSGEWSPISGIVDPGENPATTAVREAHEEAGVEVEVERLVWMVVTDPVTYPNGDECQFLDHGFRCRWLTGEARVGDDESSAVGWFRVDELPEPRQDRLDAMVRLALDDPRDVALSLEPSGRPLAPDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFZ7</accession>
    <name>A0A1Q2CFZ7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09440</name>
        <name evidence="3" type="ORF">SAMN05428934_102418</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY60214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44980">
        <property type="protein sequence ID" value="AQP44980"/>
        <property type="gene ID" value="RPIT_09440"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY60214">
        <property type="protein sequence ID" value="SDY60214"/>
        <property type="gene ID" value="SAMN05428934_102418"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09440"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY60214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="62" mass="7061" checksum="58EC629993FB6439" modified="2017-04-12" version="1">MTQQHAKNSLQADMEALAEVFDAEDREDRRKEAQRRRDGLAEPKRDIRTFDGFADGGAAPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG14</accession>
    <name>A0A1Q2CG14_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Succinate--CoA ligase [ADP-forming] subunit beta</fullName>
            <ecNumber evidence="6">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Succinyl-CoA synthetase subunit beta</fullName>
            <shortName evidence="6">SCS-beta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sucC</name>
        <name evidence="9" type="ORF">RPIT_09870</name>
        <name evidence="10" type="ORF">SAMN05428934_102332</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + CoA + succinate = ADP + phosphate + succinyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterotetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the succinate/malate CoA ligase beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY57817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09870"/>
    <dbReference type="EnsemblBacteria" id="AQP45056">
        <property type="protein sequence ID" value="AQP45056"/>
        <property type="gene ID" value="RPIT_09870"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57817">
        <property type="protein sequence ID" value="SDY57817"/>
        <property type="gene ID" value="SAMN05428934_102332"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09870"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00558">
        <property type="entry name" value="Succ_CoA_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013650">
        <property type="entry name" value="ATP-grasp_succ-CoA_synth-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005809">
        <property type="entry name" value="Succ_CoA_synthase_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="PTHR11815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08442">
        <property type="entry name" value="ATP-grasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001554">
        <property type="entry name" value="SucCS_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01016">
        <property type="entry name" value="sucCoAbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="ATP-grasp" evidence="8">
        <location>
            <begin position="9"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding; shared with subunit alpha" evidence="6">
        <location>
            <begin position="320"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="53"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit alpha</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY57817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="391" mass="41307" checksum="342E97060A616100" modified="2017-04-12" version="1">MDLLEYQARDLFEQFGVPVLPGRTATTPDEARTAYAELGSDLVVIKAQVRTGGRGKAGGVKLARGEEAVVKTAAEILDLEIKGHKVETVMISPGADIAEEFYFSILLDRASGGYLAMVSTEGGVDIETLAEERPEALLKVGLDPVDGITDAVGRKIVEEAGFMPDDHAAVIDVLKKLWTVFRESDATLVEVNPLVRTGSGQIIALDGKVTLDENADFRHEEWESYTETSGAVDLERQARELDLNYVKLDGTVGIIGNGAGLVMSTLDVVAAAGEDLPGTPKPANFLDIGGGASATVMANGLRIIMSDPQVKSVFVNVFGGITACSDVANGIVHALEMLGDEARLPIVVRLDGNSVEVGKAILAEANHPLITVKNTMDEAARAAARLASEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGA2</accession>
    <name>A0A1Q2CGA2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_10260</name>
        <name evidence="10" type="ORF">SAMN05428934_102253</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="7">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10260"/>
    <dbReference type="EnsemblBacteria" id="AQP45127">
        <property type="protein sequence ID" value="AQP45127"/>
        <property type="gene ID" value="RPIT_10260"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55671">
        <property type="protein sequence ID" value="SDY55671"/>
        <property type="gene ID" value="SAMN05428934_102253"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10260"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000813">
        <property type="entry name" value="7Fe_ferredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00354">
        <property type="entry name" value="7FE8SFRDOXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY55671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="105" mass="11562" checksum="2042F62F08FA5F85" modified="2017-04-12" version="1">MTYIIGLPCVDVKDRACVEECPVDCIYEGNRMLYIHPEECVDCGACEPVCPVEAIYYEDDVPEEQAEYYDVNVQFFDDIGSPGGAAKMGVIDKDHPVVAALPPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGA9</accession>
    <name>A0A1Q2CGA9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Pyridoxamine 5'-phosphate oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_10385</name>
        <name evidence="10" type="ORF">SAMN05428934_102228</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="5">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the pyridoxamine 5'-phosphate oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY54983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10385"/>
    <dbReference type="EnsemblBacteria" id="AQP45151">
        <property type="protein sequence ID" value="AQP45151"/>
        <property type="gene ID" value="RPIT_10385"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY54983">
        <property type="protein sequence ID" value="SDY54983"/>
        <property type="gene ID" value="SAMN05428934_102228"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10385"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004733">
        <property type="term" value="F:pyridoxamine-phosphate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000659">
        <property type="entry name" value="Pyridox_Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019576">
        <property type="entry name" value="Pyridoxamine_oxidase_dimer_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851">
        <property type="entry name" value="PTHR10851"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10590">
        <property type="entry name" value="PNP_phzG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000190">
        <property type="entry name" value="Pyd_amn-ph_oxd"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 5" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="7">
        <location>
            <begin position="40"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="PNP_phzG_C" evidence="8">
        <location>
            <begin position="144"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="67"/>
            <end position="72"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000190-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY54983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="187" mass="20852" checksum="49D1DDEDB9CDC717" modified="2017-04-12" version="1">MSGDLRDVLRALPGFPPSLPELSVEEAPEDPTVLFRRWLNDAIAEGSRQPHAFDLLTLRPDGAPVGRVLIVKEIDGRGVHFSTHESSRKGAHLAANPVASMLFFWRESGRSVRLTGTVDSLSDEESARDWEQRPNYDGAPNPDWRLYALAPTEAEFMQAREDRRHVRVEYLLGADGWSRGHVTTPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGC6</accession>
    <name>A0A1Q2CGC6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA recombination protein RmuC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_10500</name>
        <name evidence="5" type="ORF">SAMN05428934_102205</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in DNA recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RmuC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY54293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10500"/>
    <dbReference type="EnsemblBacteria" id="AQP45172">
        <property type="protein sequence ID" value="AQP45172"/>
        <property type="gene ID" value="RPIT_10500"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY54293">
        <property type="protein sequence ID" value="SDY54293"/>
        <property type="gene ID" value="SAMN05428934_102205"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10500"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003798">
        <property type="entry name" value="DNA_recombination_RmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30563">
        <property type="entry name" value="PTHR30563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02646">
        <property type="entry name" value="RmuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="482"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY54293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="506" mass="55934" checksum="606ABD94B058F399" modified="2017-04-12" version="1">MEIATVVVFVLLALIVGIVGGFVVGRRGGAPDEQARQAEQRALSDARSDAATARAEASRAREESAHIKAEVAQHLAEKSDLRTAVAEAQRLVAEARGETARVAAEVAAAVAQRDAAMQRAAEQASDREALLNQFKVLSSETLERQGKQADAVAEARMKATEQLVSPLTEGLRQMQEKLQNVEKERVRLAAELGEQVNMVRLSGEAIRRETTSLSNALRTPQVRGAWGERSLRRIVESSGLHERCDFDTQHSYETDDGRFRPDLRVNLPAAKVLFVDAKVPLQAVLEAYNTEDEAQQKGHFKTFSRHVRTHIDQLSDKNYWALDQGSPEFVVMYLPSDEFYRLALEQDPALHDYATRKQVVLSSPGLLIPMLQVVANGWKQVALAEQAGEVSKLGRELYERLATLGAHFDKLGRSLGSAVSNYNKAVATMESRVMVSARRFRDLEVTSAELPELGGIDGTTRELAVAEMLDYQEIRERELATLNDDERIEDASPVRQLPRRTGTSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGC7</accession>
    <name>A0A1Q2CGC7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome-binding ATPase YchF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ychF</name>
        <name evidence="7" type="ORF">RPIT_10465</name>
        <name evidence="8" type="ORF">SAMN05428934_102212</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY54511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10465"/>
    <dbReference type="EnsemblBacteria" id="AQP45166">
        <property type="protein sequence ID" value="AQP45166"/>
        <property type="gene ID" value="RPIT_10465"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY54511">
        <property type="protein sequence ID" value="SDY54511"/>
        <property type="gene ID" value="SAMN05428934_102212"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10465"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01900">
        <property type="entry name" value="YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00944">
        <property type="entry name" value="YchF_OLA1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041706">
        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00092">
        <property type="entry name" value="TIGR00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="5">
        <location>
            <begin position="3"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="6">
        <location>
            <begin position="272"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY54511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="363" mass="38957" checksum="412FAF0761A2FDBD" modified="2017-04-12" version="1">MALTIGIVGLPNAGKSTLFNALTRNNVLAANYPFATIEPNVGVVGVPDDRLPQLAKIYGSERIVPATVSFVDIAGIVKGASQGEGMGNAFLANIREADAICQVTRVFVDDDVTHVDGKVDPASDIDTITTELIMADLATVEKALPRVEKDARLKKELQPKLEAYRAAKDALESGKGVRAAGLDVTELRDLFLLTAKPYIYVFNCDQDELADEDLKARMREVVAPAEAIFLDAKFESELVEMDEDEGREFLAEMGVEEPGLDVLARVGYDTLGLQSYLTAGPKESRGWTIPKGATAPEAAGVIHTDFQKGFIKAQVVSFDDLIAAGSENAAKAAGKMRLEGKDYVMQDGDVVEFRSGITSGGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGG4</accession>
    <name>A0A1Q2CGG4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glyoxylase, beta-lactamase superfamily II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10300</name>
        <name evidence="3" type="ORF">SAMN05428934_102245</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10300"/>
    <dbReference type="EnsemblBacteria" id="AQP45135">
        <property type="protein sequence ID" value="AQP45135"/>
        <property type="gene ID" value="RPIT_10300"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55445">
        <property type="protein sequence ID" value="SDY55445"/>
        <property type="gene ID" value="SAMN05428934_102245"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10300"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="21"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY55445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="182" mass="19170" checksum="A0D09471471EC13E" modified="2017-04-12" version="1">MTVRRVAPSAEPMPLAAPGSVYNAWVVGDERETIVIDAPHDAESILSAVAGRRVLAVLCTHAAGVRAAPDLAERTGAPIWVHPEASAGWYRAHPVRDWDCDLALGQEFSVGAVTLEVISDPTPRSPGVVLYSPTLGCVFTGALTGVDAESAWEELSALPPETVIHPGHGPDSVLVEHLSSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGI6</accession>
    <name>A0A1Q2CGI6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10410"/>
    <dbReference type="EnsemblBacteria" id="AQP45155">
        <property type="protein sequence ID" value="AQP45155"/>
        <property type="gene ID" value="RPIT_10410"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10410"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="36"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="306" mass="32859" checksum="5F88833734EEED18" modified="2017-04-12" version="1">MRRVASSWRWDAPDGGGSWDLHIEHVGAPTASVRMLLVHGAGGNAAAMWPYAAHLSRLGARVTVVDLPGCGRTIRVRRGRRSVSYGDWQQLLVDLVGREHDERPLVLVGASMGGALAVDTAAVTGLAKRVIATCLLDPTRPGIAAAIVRAPWIARLGLPLLQFARGPAANPRIPVRVLTPMSAISNDPGLSHAVLTDPCGGGGAMPVGWYRSFLEAGPAIPPEQYQGPPVVLLHPAEDRWTMPELSLDYLGRLHGKTRVVMLPGCGHFPSRSPASRSSWTRFRMSWNRCWMTSGEAAESAMRGEGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGL3</accession>
    <name>A0A1Q2CGL3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10665</name>
        <name evidence="2" type="ORF">SAMN05428934_102172</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY53289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45200">
        <property type="protein sequence ID" value="AQP45200"/>
        <property type="gene ID" value="RPIT_10665"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY53289">
        <property type="protein sequence ID" value="SDY53289"/>
        <property type="gene ID" value="SAMN05428934_102172"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10665"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY53289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="159" mass="17943" checksum="F77983EF892EACDE" modified="2017-04-12" version="1">MSVNMEKFEGKWSRPKTGDVFEIRIGGYRCPGRVVSTEAKPLGKGAPDAPLVYLFHPVSPQWEFDQREVLQVTNLLVSPIMTNLKPWTLKYFRTLGNVGFADGERLERHCFRSSFGRFYDEQGNEIQEPVSPVGTWGLHSFRTIDDALSEALGIPLAPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGN4</accession>
    <name>A0A1Q2CGN4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SAF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11040"/>
    <dbReference type="EnsemblBacteria" id="AQP45263">
        <property type="protein sequence ID" value="AQP45263"/>
        <property type="gene ID" value="RPIT_11040"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11040"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013974">
        <property type="entry name" value="SAF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08666">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00858">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAF" evidence="1">
        <location>
            <begin position="42"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="205" mass="20690" checksum="76920D33512003EF" modified="2017-04-12" version="1">MRPLRSAATFVSWHRRLIGSVLIAASVVTIAQWVARPAPETRAVVTLAVDLTAGQLISAEHVEMRQIPDSALPLGAFSSDDGVVGRAVAVGLSRGTVLQDGLLASGQEVSAGRAAVPITLPDARLLTLLRPGDAVTLVAVGMDSADVITDLARIAALPTESQPGVLSVGSGGAGGLVLVDVPVDQAPRVAAMGQTGQLSVILGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGQ9</accession>
    <name>A0A1Q2CGQ9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cysteine--tRNA ligase</fullName>
            <ecNumber evidence="11">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cysteinyl-tRNA synthetase</fullName>
            <shortName evidence="11">CysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cysS</name>
        <name evidence="13" type="ORF">RPIT_11265</name>
        <name evidence="14" type="ORF">SAMN05428934_10250</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys)</text>
            <dbReference type="Rhea" id="RHEA:17773"/>
            <dbReference type="Rhea" id="RHEA-COMP:9661"/>
            <dbReference type="Rhea" id="RHEA-COMP:9679"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78517"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 11">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY49581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11265"/>
    <dbReference type="EnsemblBacteria" id="AQP45301">
        <property type="protein sequence ID" value="AQP45301"/>
        <property type="gene ID" value="RPIT_11265"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY49581">
        <property type="protein sequence ID" value="SDY49581"/>
        <property type="gene ID" value="SAMN05428934_10250"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11265"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015273">
        <property type="entry name" value="Cys-tRNA-synt_Ia_DALR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="PTHR10890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09190">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00840">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11 14" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 11 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DALR_2" evidence="12">
        <location>
            <begin position="357"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="11">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="11">
        <location>
            <begin position="270"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP45301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY49581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="481" mass="52531" checksum="3A2C4574694023B1" modified="2017-04-12" version="1">MTLKLYDTATRSTREFVPLVAGKVGIYHCGLTVQASPHLGHIRKEVVFDVLRRWLEHEGLDVTVVANVTDIDDKILAKSAEAGVEWFAHAYHFERELHEAYAALGCKPPTYEPRATGHIPEMIELTQVLIDRGHAYPAPDGSGDVYFDVKSWPRYGELSGMKVDEMEAAADADPRGKRDPRDFALWKGHKEGEPTTASWPSPWGRGRPGWHLECSAMAGKYLGDTFDIHGGGIDLRFPHHENELAQSAAAGHGFARYWMHNAWVTMAGEKMSKSLGNTAQVSEVTKTYNPRAVRFFLLAPHYRSTIEFSPADDGTRGSLAEAEKAIERVDSFVERAREFLATDEGTPDPQSVAQYAAFIQAMNDDLSTPAATASLFDAIRGGNQAIADGDAVRARSFAAAVTQMLNVFGIHPEAPEWAGKAAGSDLTPVVDGLVGALLAQRAKAREAKDWAAADAIRDTLADLGLVITDTPAGPRWSLEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGW8</accession>
    <name>A0A1Q2CGW8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Lipid II flippase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_11605</name>
        <name evidence="11" type="ORF">SAMN05428934_106154</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the MurJ/MviN family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY94045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11605"/>
    <dbReference type="EnsemblBacteria" id="AQP45362">
        <property type="protein sequence ID" value="AQP45362"/>
        <property type="gene ID" value="RPIT_11605"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY94045">
        <property type="protein sequence ID" value="SDY94045"/>
        <property type="gene ID" value="SAMN05428934_106154"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11605"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13123">
        <property type="entry name" value="MATE_MurJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004268">
        <property type="entry name" value="MurJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03023">
        <property type="entry name" value="MurJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002869">
        <property type="entry name" value="MviN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01806">
        <property type="entry name" value="VIRFACTRMVIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01695">
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            <end position="67"/>
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            <begin position="94"/>
            <end position="114"/>
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    </feature>
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            <end position="155"/>
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            <dbReference type="PIRNR" id="PIRNR002869"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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        <source>
            <dbReference type="EMBL" id="AQP45362.1"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY94045.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="518" mass="53680" checksum="CC50E16F62D9EF4E" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH19</accession>
    <name>A0A1Q2CH19_9ACTN</name>
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        <submittedName>
            <fullName evidence="4">BMP family ABC transporter substrate-binding protein</fullName>
        </submittedName>
        <submittedName>
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        </submittedName>
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    </gene>
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
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            <taxon>Bacteria</taxon>
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    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45345.1"/>
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    </dbReference>
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        <property type="protein sequence ID" value="SDY48058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11495"/>
    <dbReference type="EnsemblBacteria" id="AQP45345">
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        <property type="gene ID" value="RPIT_11495"/>
    </dbReference>
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        <property type="gene ID" value="SAMN05428934_1024"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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            <begin position="1"/>
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        </location>
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            <begin position="36"/>
            <end position="360"/>
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            <end position="58"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP45345.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY48058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="360" mass="37244" checksum="0C4FB1254E7A6A3A" modified="2017-04-12" version="1">MRNLRSALALTSVLALGLTACGTSTDETTNEPAPAETTAAAPETTAAETETTPAETEPTDSEPAEAGDVPKGNGETIYLVSKGFQHRFWQAVKEGAEQAGQEYNYTIEFVGPQDETKVTEQLDMLKTALDSQPAAIGLAALDSGAAESLLTEIQAANIPIIAFDSGVDSDIPLTTVSTDNTAAAAEAAKHMAELIGNTGTVGLICHDQTSATGKQRCDGFQDWMAENAPDITVLEPQVAGEVGLAANTAKSMIQANPDLVGIYGTNEAAATGAIQGANESGKEGLTVVGFDSGKTQLEAIRNGSQAGAVTQSPVLMGYETVVAAIKAINGQELPETIDSGFAWYDASNIDDPEIAGNLYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH93</accession>
    <name>A0A1Q2CH93_9ACTN</name>
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        <submittedName>
            <fullName evidence="3">YwiC-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12275</name>
        <name evidence="3" type="ORF">SAMN05428934_10621</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY91129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12275"/>
    <dbReference type="EnsemblBacteria" id="AQP45482">
        <property type="protein sequence ID" value="AQP45482"/>
        <property type="gene ID" value="RPIT_12275"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY91129">
        <property type="protein sequence ID" value="SDY91129"/>
        <property type="gene ID" value="SAMN05428934_10621"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12275"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025576">
        <property type="entry name" value="YwiC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14256">
        <property type="entry name" value="YwiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY91129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="254" mass="27872" checksum="3D3FBFE66ACAA81F" modified="2017-04-12" version="1">MARKIPAGWVPKQHGAWAMIIVPYVTGLLLAARLRPLEWSDATLGLTWLVGYFAFNAATLWLKAPARRRASFQTPLITYLGISAVFGVATLIQKGWPILIWVPPYAVVLGISLWLAASKRERSLLSGVLTVVASCGLMAVLRPWPADDPARLPDLAVMAAVTLYFVGTVFHVKALIRERNDPHSARRSGIYHTAVLAALVAGIGLGWLTWPWSLWGVALVGRSFRMPRAPRRPLQIGLVEIALSTWALLLVLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH96</accession>
    <name>A0A1Q2CH96_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Uracil phosphoribosyltransferase</fullName>
            <ecNumber evidence="3 11">2.4.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">UMP pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">UPRTase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">upp</name>
        <name evidence="12" type="ORF">RPIT_12270</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>diphosphate + UMP = 5-phospho-alpha-D-ribose 1-diphosphate + uracil</text>
            <dbReference type="Rhea" id="RHEA:13017"/>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="11">Allosterically activated by GTP.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uracil: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the UPRTase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.9" evidence="3 11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12270"/>
    <dbReference type="EnsemblBacteria" id="AQP45481">
        <property type="protein sequence ID" value="AQP45481"/>
        <property type="gene ID" value="RPIT_12270"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12270"/>
    <dbReference type="UniPathway" id="UPA00574">
        <property type="reaction ID" value="UER00636"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004845">
        <property type="term" value="F:uracil phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044206">
        <property type="term" value="P:UMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006223">
        <property type="term" value="P:uracil salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01218_B">
        <property type="entry name" value="Upp_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034332">
        <property type="entry name" value="Upp_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005765">
        <property type="entry name" value="Ura_phspho_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01091">
        <property type="entry name" value="upp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="5 11 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11 12" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="5-phospho-alpha-D-ribose 1-diphosphate binding" evidence="11">
        <location>
            <begin position="130"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Uracil binding" evidence="11">
        <location>
            <begin position="202"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>uracil</name>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP45481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="213" mass="22889" checksum="88D17098295B8252" modified="2017-04-12" version="1">MEVTVVSHPLVDHKLTLLRKKDTEQPVFRRLVEELVTLLAYEATRGVRVGSVDIETPVTSTTGVKLSQPAPLVVPILRAGLGMLDGMLRLVPTAEVGFLGMIRDEETLQPMTYAERLPHDLSGRQCYVLDPMLATGGSLGGAVQFLVDRGADDITAICLLAAPEGIEKLRDLLAGLHVPCNLVVAAVDERLNEVGYIVPGLGDAGDRLYGLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHB6</accession>
    <name>A0A1Q2CHB6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sialidase-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12385</name>
        <name evidence="3" type="ORF">SAMN05428934_104208</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY80778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12385"/>
    <dbReference type="EnsemblBacteria" id="AQP45501">
        <property type="protein sequence ID" value="AQP45501"/>
        <property type="gene ID" value="RPIT_12385"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY80778">
        <property type="protein sequence ID" value="SDY80778"/>
        <property type="gene ID" value="SAMN05428934_104208"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12385"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004308">
        <property type="term" value="F:exo-alpha-sialidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011040">
        <property type="entry name" value="Sialidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026856">
        <property type="entry name" value="Sialidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10628">
        <property type="entry name" value="PTHR10628"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13088">
        <property type="entry name" value="BNR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sialidase" evidence="1">
        <location>
            <begin position="107"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY80778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="364" mass="38898" checksum="F1742EBAF3BC2F29" modified="2017-04-12" version="1">MITSVLTQRGDPFDGAAFTSPCYRIPALAVTPACRLLAAWDVRADWRDLPGPFDVVYRCSDDLGHSWGPLRVLRRHTASEGFGDASFVVGPGVVHCWYVSSAGRSFFDAEPGAGEGLRLWLASSFDDGQTWQHRDLTASLKPDDVTGMFASSGNGLTLREGARAGRLLQPFVLRTAAGQHFAAMAYSDDDGTTWALGERIGPDCDENKVTELPGGRVLLHARATPRRRWAVSDDGGVTFGDPVAHEQLVDPACNGGLSRWGSQVVATILNHPSERRELAIRRSADGGESWTPALGIDDGACAYSVALELPDGALAVAWESGDYDVIVFARIARDEVGFDGGEPTLRAIRGRAGAAAPPEVAPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHE6</accession>
    <name>A0A1Q2CHE6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Alpha-amylase</fullName>
            <ecNumber evidence="7">3.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_12550</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Endohydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1-&gt;4)-alpha-linked D-glucose units.</text>
            <dbReference type="EC" id="3.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12550"/>
    <dbReference type="EnsemblBacteria" id="AQP45531">
        <property type="protein sequence ID" value="AQP45531"/>
        <property type="gene ID" value="RPIT_12550"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12550"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031319">
        <property type="entry name" value="A-amylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006046">
        <property type="entry name" value="Alpha_amylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00110">
        <property type="entry name" value="ALPHAAMYLASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00632">
        <property type="entry name" value="Aamy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010264658" description="Alpha-amylase" evidence="8">
        <location>
            <begin position="25"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Aamy" evidence="10">
        <location>
            <begin position="42"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Aamy_C" evidence="9">
        <location>
            <begin position="397"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP45531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="485" mass="52430" checksum="70CB94003DA106FC" modified="2017-04-12" version="1">MRRLALPLAALVAVVGCSPSTPTATTTPTPTPSILSVEPERQVGVQLFQWNWPSVGRECTEVLGPNQFAFVLLSPAQEHIVGEQWWTSYQPVSYQLESKLGTRDEFEEMVSTCHEAGVKVIADAVINHMAGIDGGTGVAGTEFTHYEYPGLYGPDDFHTCDTPGGDIVNYVDQQEVQECELSNLADLRTGEPEVQSTIVSYLDDLTSLGVDGFRIDAAKHMHHRDVQEIVDQLSGDPIIISEVIRASSEPIQPEDYLEIGSVFAFQVAKDLAGLVPGGALHRALDLKDGQVPSEQAYTFVTNHDTERNRQTLSYKDADKYRVANYLLLAQPYGTPVLYSGYAFTDRDEGAPQTDGGVDDVECATPSDDPAPGDWLCQHRTDAGMAEWVAVVGDEPIGDLWREGYAIGFDRGDRGLIVINGNSTLDVSPELTTSLPDGAYCNAADLPPSGAEDRCADGEFIVADGKVTVPVSPMSAVALHVNLRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHK0</accession>
    <name>A0A1Q2CHK0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4185 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12865</name>
        <name evidence="3" type="ORF">SAMN05428934_104114</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
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</entry>
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            <end position="79"/>
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        <location>
            <begin position="91"/>
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    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
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</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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                <person name="Lal R."/>
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            </authorList>
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        </source>
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            <text>a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate</text>
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            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.1.5.3"/>
        </reaction>
    </comment>
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        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
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        <property type="protein sequence ID" value="AQP45702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="AQP45702">
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    </dbReference>
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            <dbReference type="Pfam" id="PF16901"/>
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    </evidence>
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    </evidence>
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            <dbReference type="EMBL" id="SDZ13314.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="572" mass="62026" checksum="858E7A593C7B9FE4" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHX4</accession>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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    </reference>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
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    </evidence>
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</entry>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
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                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP45744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13785"/>
    <dbReference type="EnsemblBacteria" id="AQP45744">
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        <property type="gene ID" value="RPIT_13785"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ12395"/>
        <property type="gene ID" value="SAMN05428934_11143"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544508" evidence="3">
        <location>
            <begin position="31"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ12395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="497" mass="51974" checksum="A1D50C77989E4293" modified="2017-04-12" version="1">MSLKDFLSILRHRWLVIVLCVLIAAGVVFAITPAERDVSPRIGSYTATSTLLVGSVGAPDAGAGYASLGRVALFITTGEVPRNAAAALGYEGDPALLAKQITVETQGESASVTITTTASDGERAANVVNTFANETIAFFETSPPGAETTRLSVLQEATPIPNESTANFVIPPDRWFRTLLAAVLGLLFGIALALVLERLDSRLRTREEIAEALDMPIVGVVPKITAAQRRNKEILTVTQPLSPYADGYRSVRAALAHGQAEAAPARGHQSLVVLVSSAHVAEGKSTSTANLAASFAETGKQVLVIDADLRSPDVHEKLDVPQGAGVSDLLVDGQGSLNSVIRPTNIPGVRVVTAGTRLAHPTALASRMGPLVASARKRADVVIIDSAPLLEAAEVFDILPHVDDVVLVARSGRLSAASAQRTKEMLARFNIPVVGAVIVGAPLRKGDIGYGSGYGYGYGETKGKAKGKRGGARAVADEKPEASLVEPAEDVQAQRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
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    <name>A0A1Q2CI62_9ACTN</name>
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        </submittedName>
        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">RPIT_14130</name>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP45801">
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    </dbReference>
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        <property type="gene ID" value="SAMN05428934_1127"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="7"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ14303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="76" mass="7842" checksum="C80A22BB37D03E15" modified="2017-04-12" version="1">MLTTTTHTTLRAEGFSCPSCVAKIEKGLGQLPGVSAATVHFASARIEVDHDPAVTSVDDLVAAVGKLGYVARPSAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI70</accession>
    <name>A0A1Q2CI70_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized conserved protein YafD, endonuclease/exonuclease/phosphatase (EEP) superfamily</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">RPIT_13975</name>
        <name evidence="3" type="ORF">SAMN05428934_1113</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ11547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="RPIT_13975"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ11547"/>
        <property type="gene ID" value="SAMN05428934_1113"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:endonuclease activity"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ11547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="312" mass="33374" checksum="A99B915B0DDC818B" modified="2017-04-12" version="1">MRGSVQLIAWLLLLAAGALAVLHLLPRSQLLSKTVVVAASLIPYGLPLAIIGLLLLAVTGSRPLALVLAGAVLLAHILIARPYWPARAPTPPEEPITVMTMNMRCNSPGAEDLARLLRESAPDVAVINGLDPRSRDDIIGELAERYPTAEFVPLPTYPVCGTVLLTHLPFDGWVAGQRHPTALLRAPGFEFALVAVDFPTPTHGLGPWLDAFDGLIEDMPSHTGRSVVAIGDFNAVPEHEPMRRLRKETALRNAVLESGLGWLPTFPDDRAYPPLVALDHALVTPDLVASSAWTASVPGQAHRALLLTVGPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI72</accession>
    <name>A0A1Q2CI72_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EpsG family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13850</name>
        <name evidence="3" type="ORF">SAMN05428934_11130</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13850"/>
    <dbReference type="EnsemblBacteria" id="AQP45755">
        <property type="protein sequence ID" value="AQP45755"/>
        <property type="gene ID" value="RPIT_13850"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12137">
        <property type="protein sequence ID" value="SDZ12137"/>
        <property type="gene ID" value="SAMN05428934_11130"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13850"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ12137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="361" mass="39730" checksum="9368EAC3E1051EA0" modified="2017-04-12" version="1">MTPYWVTLALLAYLLVLTYQLDPAVDTKLANGLSFSTSTRICLTAAAAVLVCVAGLRWGIGTDYFGYYKGYSQSGAEFITALQAFDEPGIKGLAWATSQISDDAAVFMFAASSLTLIPILWTTVKHTNAVGMSLLLIVFVGTWHGSFNGVRQFLACAVIFAGHRFIVDRRLIPYALVVVVASSIHISALAMAVLYLVPTKQLSRRMVVLLAALALGALYSSDFMISLFERADEGFEVTEYVTHSINPLRVAVAVAPVLLYWSPGVRTRADGQWFYRNMAVVHAAVVLAASWSAYLTRFSIYTTAFLPLVLPRLIDFPNRRLTALTRAAVTLLFAVYWYTEVSGSSALNDFRFIWERQGAVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI73</accession>
    <name>A0A1Q2CI73_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">L-serine dehydratase</fullName>
            <ecNumber evidence="9">4.3.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_14195</name>
        <name evidence="13" type="ORF">SAMN05428934_11221</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>L-serine = NH4(+) + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:19169"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="EC" id="4.3.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the iron-sulfur dependent L-serine dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.17" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ14583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14195"/>
    <dbReference type="EnsemblBacteria" id="AQP45812">
        <property type="protein sequence ID" value="AQP45812"/>
        <property type="gene ID" value="RPIT_14195"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ14583">
        <property type="protein sequence ID" value="SDZ14583"/>
        <property type="gene ID" value="SAMN05428934_11221"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14195"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029009">
        <property type="entry name" value="ASB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004644">
        <property type="entry name" value="Fe-S_L-Ser_mono"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005130">
        <property type="entry name" value="Ser_deHydtase-like_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005131">
        <property type="entry name" value="Ser_deHydtase_bsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03313">
        <property type="entry name" value="SDH_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03315">
        <property type="entry name" value="SDH_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143548">
        <property type="entry name" value="SSF143548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00720">
        <property type="entry name" value="sda_mono"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 9 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SDH_beta" evidence="11">
        <location>
            <begin position="4"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="SDH_alpha" evidence="10">
        <location>
            <begin position="181"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP45812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDZ14583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="449" mass="47101" checksum="6E25593847403C74" modified="2017-04-12" version="1">MALSVFDLFSIGIGPSSSHTVGPMRAAATFRASLPNDATRVTADLFGSLGATGHGHGTPGAVVLGLLGELPETVDPRLGAERVARARETGLLDVGHEIAFSMDDDITLHRRRELPLHSNGMIFRAYTGDEMVQERTFYSVGGGFVVDGAADGDARVVQDTTAVSHRFHTGDELLALCESTGKSISRIALENELSWRSEDEVRAGLLRIWAVMQECVQAGIATEGYLPGGLKVRRRAPELAAKLAVEGDSTDPMRGMDWVTLFALAVNEENASGGRVVTAPTNGAAGIIPAVLHYYARFVPGASDDGVVRFLLTAGAVGMIFKETASISGAEVGCQGEVGSACSMAAASMAAVMGGTPQQIENAAEIGMEHNLGLTCDPVGGLVQIPCIERNAIASVKAIAAARTALRGDGRHIVSLDKVIKTMRETGADMKVKYKETARGGLAVNVIEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI83</accession>
    <name>A0A1Q2CI83_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycogen debranching enzyme</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Glycogen operon protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_14320</name>
        <name evidence="4" type="ORF">SAMN05428934_11246</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ15074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14320"/>
    <dbReference type="EnsemblBacteria" id="AQP45836">
        <property type="protein sequence ID" value="AQP45836"/>
        <property type="gene ID" value="RPIT_14320"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ15074">
        <property type="protein sequence ID" value="SDZ15074"/>
        <property type="gene ID" value="SAMN05428934_11246"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14320"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004133">
        <property type="term" value="F:glycogen debranching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02856">
        <property type="entry name" value="E_set_GDE_Isoamylase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044505">
        <property type="entry name" value="GlgX_Isoamylase_N_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="2">
        <location>
            <begin position="212"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="531"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ15074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="786" mass="87468" checksum="5C7C8A55B3994C16" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIA1</accession>
    <name>A0A1Q2CIA1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TIGR01777 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_14140</name>
        <name evidence="5" type="ORF">SAMN05428934_1129</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ14328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14140"/>
    <dbReference type="EnsemblBacteria" id="AQP45803">
        <property type="protein sequence ID" value="AQP45803"/>
        <property type="gene ID" value="RPIT_14140"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ14328">
        <property type="protein sequence ID" value="SDZ14328"/>
        <property type="gene ID" value="SAMN05428934_1129"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14140"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013549">
        <property type="entry name" value="DUF1731"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010099">
        <property type="entry name" value="SDR39U1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08338">
        <property type="entry name" value="DUF1731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01777">
        <property type="entry name" value="yfcH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="2">
        <location>
            <begin position="160"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1731" evidence="3">
        <location>
            <begin position="404"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ14328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="465" mass="49636" checksum="4DB0FB42A5454001" modified="2017-04-12" version="1">MNQPIERASDIPFPRERVFDWWLRPGSHERLSPPGWGEVIGGDRDARQVGDTVTLQPSHPLMSAIPGASLLKLRPVTARLDVVEPGERIVVALEHGRSRWTEETRFTDSGDGGTRVEQRVSGDYPASTGDAFQAQLTFLADQAEADLALVERLAARPSRIVVAGSSGLIGTQLVALLKMAGHDVTRLVRGTPEAPDEVRWDPASGEVPTDVIAGADAVVNLAGHTIGGRFTDRNKKLILQSRVDSTSTLANALRDRGSSAALIQASGIGFYGARRPAELLTEESRRGSGFLADVVDAWEAAAAPAVDAGVRTVFVRTGIALSYAGGALQRQVPLYLVGAGGRLGKAQQYQSWIGIDDLVRAYVHALFTPDLSGPINAVAPNPVTNAKFAETLGKVLQRPSLLPTPSFGPKLIVGDEGYDQLIDTDQRVSADKLLASGFEFTHPTLEPALRHTLLRQSGAGGHDSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIA4</accession>
    <name>A0A1Q2CIA4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Multisubunit sodium/proton antiporter, MrpF subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_14450</name>
        <name evidence="10" type="ORF">SAMN05428934_109126</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ07005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14450"/>
    <dbReference type="EnsemblBacteria" id="AQP45859">
        <property type="protein sequence ID" value="AQP45859"/>
        <property type="gene ID" value="RPIT_14450"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ07005">
        <property type="protein sequence ID" value="SDZ07005"/>
        <property type="gene ID" value="SAMN05428934_109126"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14450"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015075">
        <property type="term" value="F:ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007208">
        <property type="entry name" value="MrpF/PhaF-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04066">
        <property type="entry name" value="MrpF_PhaF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ07005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="106" mass="11396" checksum="9C61A4E11677F549" modified="2017-04-12" version="1">MTLLTNVILSVAAVVLAVAALIGVKRIADGPSQLDRSVAADLIVAVVVASLGLWTIWTDLSTELLVLVMLSMLGFTSAVSIARMVGDRMLTRRRYTAEREHEEADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CID5</accession>
    <name>A0A1Q2CID5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Adenosine deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_14520</name>
        <name evidence="5" type="ORF">SAMN05428934_109112</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14520"/>
    <dbReference type="EnsemblBacteria" id="AQP45872">
        <property type="protein sequence ID" value="AQP45872"/>
        <property type="gene ID" value="RPIT_14520"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06738">
        <property type="protein sequence ID" value="SDZ06738"/>
        <property type="gene ID" value="SAMN05428934_109112"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14520"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019239">
        <property type="term" value="F:deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009168">
        <property type="term" value="P:purine ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006650">
        <property type="entry name" value="A/AMP_deam_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43114">
        <property type="entry name" value="PTHR43114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01430">
        <property type="entry name" value="aden_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00485">
        <property type="entry name" value="A_DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="A_deaminase" evidence="3">
        <location>
            <begin position="15"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ06738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="349" mass="37970" checksum="9CBA63AA1669DB6A" modified="2017-04-12" version="1">MAGEGERRRDLASLPKAHLHLHFTGSMSIPTLVDLAERRDMELPTKLVDGVALDVPYNKRGWNRFQHLYDVARAAVRGEHALRTVVRRAAEEDAAEGSRRLELQMDPTSYASSVGGLQEALDIVCDEAAIASAATGVQVGIVVAASRIRHPLDARTLARLAARRAGTGPGEVCAFGLNNNEREGRTEEWSGAFRIARRAGLPGVPHGGELRGARHLAQVVEHLEPSRIGHGVRAVEDPDLLSRIIDRGITFEVCPASNVHLGVFRDVDDVPLTTLLDAGASVALGADDPLLFQSRLTDQYELARSVHRLDDAGLARLARDSIRASFASDDDKRAWLADVDAWLAEELDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CID9</accession>
    <name>A0A1Q2CID9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45896">
        <property type="protein sequence ID" value="AQP45896"/>
        <property type="gene ID" value="RPIT_14670"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14670"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="59" mass="6766" checksum="12B9DE7B73AE2A8F" modified="2017-04-12" version="1">MNRRLIVQFDPDEPSMSAPTFAEPDQGPLAGGRKVNARHDLTLGLWRRDCEISRGFPRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIF6</accession>
    <name>A0A1Q2CIF6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Redox-active disulfide protein 2</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Small redox-active disulfide protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_14760</name>
        <name evidence="5" type="ORF">SAMN05428934_10968</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14760"/>
    <dbReference type="EnsemblBacteria" id="AQP45909">
        <property type="protein sequence ID" value="AQP45909"/>
        <property type="gene ID" value="RPIT_14760"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05878">
        <property type="protein sequence ID" value="SDZ05878"/>
        <property type="gene ID" value="SAMN05428934_10968"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14760"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005243">
        <property type="entry name" value="Redox_disulphide_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36450">
        <property type="entry name" value="PTHR36450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13192">
        <property type="entry name" value="Thioredoxin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037031">
        <property type="entry name" value="Redox_disulphide_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00412">
        <property type="entry name" value="redox_disulf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="3">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="10"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="2">
        <location>
            <begin position="10"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR037031-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR037031-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ05878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="80" mass="8464" checksum="1CCAD228E8EE4071" modified="2017-04-12" version="1">MEIKVLGPGCKNCVNLEKNVREALSTLGQDAVVVKITEYADIMAHGVMSTPGLVVDGQVVSCGRVPKPDEIVEILRGGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CII2</accession>
    <name>A0A1Q2CII2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heat shock protein Hsp15</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">RNA-binding protein S4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_14800</name>
        <name evidence="6" type="ORF">SAMN05428934_10960</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HSP15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14800"/>
    <dbReference type="EnsemblBacteria" id="AQP45917">
        <property type="protein sequence ID" value="AQP45917"/>
        <property type="gene ID" value="RPIT_14800"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05721">
        <property type="protein sequence ID" value="SDZ05721"/>
        <property type="gene ID" value="SAMN05428934_10960"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14800"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025708">
        <property type="entry name" value="HSP15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016821">
        <property type="entry name" value="HSP15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="2"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="83"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDZ05721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="122" mass="13879" checksum="C1B2D0173C3027BE" modified="2017-04-12" version="1">MARLDAWLWAVRLYKTRSLATAAVRGGHVRVDDKLAKASQEVVPGQVIRVRRAEHEDRLVEVLDPTLAKRVSAPLAQAAYLDRTPEKRPPIPEMVGRVAVRDRGTGRPTKRERRDIERLRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIN0</accession>
    <name>A0A1Q2CIN0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydroxyacetone kinase subunit L</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01865"/>
    <dbReference type="EnsemblBacteria" id="AQP45971">
        <property type="protein sequence ID" value="AQP45971"/>
        <property type="gene ID" value="RPIT_01865"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01865"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012737">
        <property type="entry name" value="DhaK_L_YcgS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="SSF101473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02365">
        <property type="entry name" value="dha_L_ycgS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DhaL" evidence="1">
        <location>
            <begin position="4"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="206" mass="21308" checksum="9CAC77D2D3B1B030" modified="2017-04-12" version="1">MTLDLLADWLRRFAAIIDENKTYLTELDSAIGDADHGANMARGTAAVVTHLDEATTIDGLLKKAGMTLVSTVGGTSGPLYGTLLMKMGMATGSVVELEPDQFGKALRAGLEGLIARGKTELEDKTMVDALSPAIDAYDAALADGADLWDAVDAAQQAAAAGRDATTPMVARKGRASYLGERSAGHCDPGATSSAYLFDALADVIGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIQ5</accession>
    <name>A0A1Q2CIQ5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nodulation efficiency protein D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_04445</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04445"/>
    <dbReference type="EnsemblBacteria" id="AQP46016">
        <property type="protein sequence ID" value="AQP46016"/>
        <property type="gene ID" value="RPIT_04445"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04445"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002810">
        <property type="entry name" value="NfeD-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01957">
        <property type="entry name" value="NfeD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="NfeD" evidence="3">
        <location>
            <begin position="59"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP46016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="155" mass="16436" checksum="539DE2D66095E2BE" modified="2017-04-12" version="1">MLDWIRDNLWVGWGVGALGLAAAELLTLDLTLLMLAVGAAAGGVTALIFPSLIWLQLIVAIVTAVATLFLLRPTLLEKVRKAPGYRSSLDTLVGTSGVATTEITGVTGEVKVDGQVWQARSFDPSVVISAGEHIEVYGLDGITLIIYPSQRQLGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIQ6</accession>
    <name>A0A1Q2CIQ6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Assimilatory sulfite reductase (ferredoxin)</fullName>
            <ecNumber evidence="3">1.8.7.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_14880</name>
        <name evidence="11" type="ORF">SAMN05428934_10944</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3 H2O + hydrogen sulfide + 6 oxidized [2Fe-2S]-[ferredoxin] = 7 H(+) + 6 reduced [2Fe-2S]-[ferredoxin] + sulfite</text>
            <dbReference type="Rhea" id="RHEA:23132"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="EC" id="1.8.7.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="1.8.7.1" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14880"/>
    <dbReference type="EnsemblBacteria" id="AQP45930">
        <property type="protein sequence ID" value="AQP45930"/>
        <property type="gene ID" value="RPIT_14880"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05438">
        <property type="protein sequence ID" value="SDZ05438"/>
        <property type="gene ID" value="SAMN05428934_10944"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14880"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050311">
        <property type="term" value="F:sulfite reductase (ferredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00397">
        <property type="entry name" value="SIROHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="SSF55124"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00365">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0883">Thioether bond</keyword>
    <feature type="domain" description="NIR_SIR_ferr" evidence="9">
        <location>
            <begin position="96"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="8">
        <location>
            <begin position="167"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR_ferr" evidence="9">
        <location>
            <begin position="342"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="8">
        <location>
            <begin position="418"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP45930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDZ05438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="564" mass="62226" checksum="933DF33D73D4D3B0" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIV4</accession>
    <name>A0A1Q2CIV4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH-quinone oxidoreductase subunit D</fullName>
            <ecNumber evidence="5">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">NADH dehydrogenase I subunit D</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NDH-1 subunit D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nuoD</name>
        <name evidence="8" type="ORF">RPIT_02645</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the complex I 49 kDa subunit family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02645"/>
    <dbReference type="EnsemblBacteria" id="AQP45980">
        <property type="protein sequence ID" value="AQP45980"/>
        <property type="gene ID" value="RPIT_02645"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02645"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01358">
        <property type="entry name" value="NDH1_NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001135">
        <property type="entry name" value="NADH_Q_OxRdtase_suD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014029">
        <property type="entry name" value="NADH_UbQ_OxRdtase_49kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022885">
        <property type="entry name" value="NDH1_su_D/H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993">
        <property type="entry name" value="PTHR11993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00346">
        <property type="entry name" value="Complex1_49kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="SSF56762"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01962">
        <property type="entry name" value="NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00535">
        <property type="entry name" value="COMPLEX1_49K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="2 5" id="KW-0874">Quinone</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 5 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Complex1_49kDa" evidence="7">
        <location>
            <begin position="138"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="426" mass="47323" checksum="5545F65C7B6BC209" modified="2017-04-12" version="1">MAQGGDWADIASEQAERGDETIVVNMGPQHPSTHGVLRLILEMDGETVESIRPAIGFLHTGIEKNMEYKTWTQGVTYVTRMDYVAPLFNEAAYCLAVEKLLGITDEIPERATIIRVLVMELNRIASHLVAMGTGGMEIGALTVMTIAFREREMILDFLEGLSGLRMNHAYIRPGGVANDLPEDGLAHLRTVIDWLKKHLPEYATFCNENPIFLGRLSNVGVMSLTAATMMGMSGPPLRSTGYDWDLRKTQPYCGYETYDFDVVTWDSEDSYGRFRIRLQECWESLKIVEQCYERLEATQGQPVMVADQKIAWPAQLSVGPDGQGNSNEHIKHIMGESMEALIHHFKIVTEGFKVPVGQVYQAIESPKGELGCHVVSDGGTRPYRVHFRDPGFNHLQSVPLMCEGGMMSDVVVSIASLDPVLGGVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIX3</accession>
    <name>A0A1Q2CIX3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_04830</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04830"/>
    <dbReference type="EnsemblBacteria" id="AQP46023">
        <property type="protein sequence ID" value="AQP46023"/>
        <property type="gene ID" value="RPIT_04830"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04830"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004509">
        <property type="entry name" value="Competence_ComEA_HhH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019554">
        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10531">
        <property type="entry name" value="SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00426">
        <property type="entry name" value="TIGR00426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012523908" evidence="2">
        <location>
            <begin position="26"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="3">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="3">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP46023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="196" mass="19466" checksum="61C183C29FD43EBE" modified="2017-04-12" version="1">MPAVTARHVAVVVVLLLCAVGVAFAALGRSAATEIPVAPVVVTSTPPPSPSAPPTVRVHVAGAVARPGVVRVPAASIVQDALLAAGGLTPEADAALLNLAAPVADGMQIVVGTGDEPMGEIRQGDGGEGGSTSELDLNSATAAELESLPGIGPVTAASIVAWREEHGRFTSVAELQEVSGIGPKTFEKLAPLVRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIX6</accession>
    <name>A0A1Q2CIX6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-phosphoshikimate 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">5-enolpyruvylshikimate-3-phosphate synthase</fullName>
            <shortName evidence="7">EPSP synthase</shortName>
            <shortName evidence="7">EPSPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">aroA</name>
        <name evidence="9" type="ORF">RPIT_06815</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21256"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="EC" id="2.5.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the EPSP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.19" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06815"/>
    <dbReference type="EnsemblBacteria" id="AQP46062">
        <property type="protein sequence ID" value="AQP46062"/>
        <property type="gene ID" value="RPIT_06815"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06815"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00089"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003866">
        <property type="term" value="F:3-phosphoshikimate 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01556">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00210">
        <property type="entry name" value="EPSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006264">
        <property type="entry name" value="EPSP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023193">
        <property type="entry name" value="EPSP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000505">
        <property type="entry name" value="EPSPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01356">
        <property type="entry name" value="aroA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00104">
        <property type="entry name" value="EPSP_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00885">
        <property type="entry name" value="EPSP_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EPSP_synthase" evidence="8">
        <location>
            <begin position="7"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate-3-phosphate binding" evidence="7">
        <location>
            <begin position="20"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoenolpyruvate" evidence="7">
        <location>
            <begin position="87"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate-3-phosphate binding" evidence="7">
        <location>
            <begin position="159"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="303"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP46062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="416" mass="43535" checksum="5543A7957E4F1937" modified="2017-04-12" version="1">MSLPHAASPVVGEVVVPGSKSETNRALVLAALADAPSRLTGALQSRDSDLMIGALRKLGILVEPSAGTLLVTPPGQFRGAQDIDCGLAGTVMRFVPPVAALADGPSSFVGDPHASERPMAPLLDGLRQLGCRVTGDSLPFTVEPAGRTGRETSIDASGSSQFVSGLLLIGALLPHGLQVRHTGATLPSRPHIDMTVHMLRARGVRIDEPDERTWVVHPGPITALDHVIEPDLTNASVFLAAAALTEGDVSVSGWPEASLQPGALFLDVAERMGADVARDVGSVRLRGRGPLRGIDVDLTAASELTPVVAALAALAEGTTRIRGVGHIRGHETDRLAALVRELARLGAVAEETADGIVIEGGHPLRPTTVETYADHRMVHFAALVGLVTPGTHVTDLQCVSKTMPDFERDWRGLVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ11</accession>
    <name>A0A1Q2CJ11_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Co-chaperonin GroES</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">10 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Chaperonin-10</fullName>
            <shortName evidence="3">Cpn10</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">groES</name>
        <name evidence="3" type="synonym">groS</name>
        <name evidence="5" type="ORF">RPIT_09970</name>
        <name evidence="6" type="ORF">SAMN05428934_102312</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the GroES chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY57228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09970"/>
    <dbReference type="EnsemblBacteria" id="AQP46116">
        <property type="protein sequence ID" value="AQP46116"/>
        <property type="gene ID" value="RPIT_09970"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57228">
        <property type="protein sequence ID" value="SDY57228"/>
        <property type="gene ID" value="SAMN05428934_102312"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09970"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018369">
        <property type="entry name" value="Chaprnonin_Cpn10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="PTHR10772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00681">
        <property type="entry name" value="CHAPERONINS_CPN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP46116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY57228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="98" mass="10616" checksum="0CBF655CC06361E3" modified="2017-04-12" version="1">MATTIKPLEDRILIQPLEATTQTASGIYIPDTAKEKPQEGKVIATGPGRIDDKGNRVPLDVAEGDVVIFSKYGGTEVKYDGQEYLLLNARDILAVVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ39</accession>
    <name>A0A1Q2CJ39_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12780"/>
    <dbReference type="EnsemblBacteria" id="AQP46158">
        <property type="protein sequence ID" value="AQP46158"/>
        <property type="gene ID" value="RPIT_12780"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12780"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045830">
        <property type="entry name" value="AraR_wHTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19368">
        <property type="entry name" value="AraR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="24"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="242" mass="25917" checksum="B4D0179FBA401910" modified="2017-04-12" version="1">MGGAQETGAQVEPVVRDSAGIARYRHEAICAVLRVTDGRLAVLLSTRVSPPFAGLHTLPSGAVEPEETLDQAVLRHLAAKVDVAGLAHLEQLGTQSDPHRDPAQRTIGTGYLGLMQASNEPHLPDGAGWFDVDELPAMGFDHAAVVARAIERLRAKLSYTNLGFALAPDEFTIGELREVYVAALGHDVSATNLQRILTRRGQLEATGAKHPVGSKGGRPAQVFRFVDRTLVVTDPFAVLRPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ72</accession>
    <name>A0A1Q2CJ72_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13490"/>
    <dbReference type="EnsemblBacteria" id="AQP46169">
        <property type="protein sequence ID" value="AQP46169"/>
        <property type="gene ID" value="RPIT_13490"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13490"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011045">
        <property type="entry name" value="N2O_reductase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011964">
        <property type="entry name" value="YVTN_b-propeller_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50974">
        <property type="entry name" value="SSF50974"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02276">
        <property type="entry name" value="beta_rpt_yvtn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012749568" evidence="2">
        <location>
            <begin position="33"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="396" mass="39938" checksum="ACEA531414F79678" modified="2017-04-12" version="1">MRTTKRSWRRPATLTVLATVALALSACGQGEGTDPNPGTTTPGRVATDDGATVATEDATASGSTPEIASVDGTVWVANEDGDSLSALDAATGEVVTTVTGIESPHNVQVSPDGSTVWAVSGHNNALVALDAETYELRGTAPTGTSPAHVIVTPDGETVYVTNAGDDTMSIYEADSLELRATIDLSAGPHGLRASPDGSTVVVANTTAGAIDVVDTATNAVAASIPVGDSPPQVAVSADGRYVYVTLIGSSSVVKVDLAEQQVIGSVAVPAPPVQLYLTADGARLLSADQGTDGTPGTTVTMIDPESMTVESTVQAGSGPHGVVIEPTGQRAWVTNLYDDTVSVIDLTAKATMATVTVGDKPNGISYSPLPPAPGPGTVEITVPEYATATGAGHDEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ79</accession>
    <name>A0A1Q2CJ79_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_14145</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14145"/>
    <dbReference type="EnsemblBacteria" id="AQP46186">
        <property type="protein sequence ID" value="AQP46186"/>
        <property type="gene ID" value="RPIT_14145"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14145"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="464"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="4"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="497"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP46186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="667" mass="71824" checksum="74C6C087F26D3A8F" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ87</accession>
    <name>A0A1Q2CJ87_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CCA tRNA nucleotidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_13110</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
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    <dbReference type="Proteomes" id="UP000188324">
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PolA_pol_head_dom"/>
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        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02692">
        <property type="entry name" value="tRNA_CCA_actino"/>
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    </dbReference>
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    </dbReference>
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    <feature type="domain" description="HD" evidence="3">
        <location>
            <begin position="255"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP46164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="466" mass="52531" checksum="BBD1176E2E9E2402" modified="2017-04-12" version="1">MQQLLRIAPVIDDLGNLFRAEGHELFLVGGSVRDALLGSLGHDLDFTTSATPDETHALLRRFTPSTWDIGKDFGTIGALKRADGQEWQIEVTTFRADIYRSESRKPEVSFGDSIDGDLIRRDFTVNAMAVDVATRAFVDPYGGLDDLADGVIRTPSTPERSFSDDPLRMMRAARFASRLGFIVADEVVRAMTDMAERITIVSAERIQAELSGLLLTDSPRAGLDLLVRTGIADYILPELPALKLELDEHHRHKDVYQHSLTVLDQAIALEKDRGHEPDIVNRLAALLHDIGKPVTRRFEGSKVTFHHHDVVGAKLAKKRLRALNYPSAVVKSVARLIDLHLRFHGYSDGEWSDSAVRRYVRDAGDELERLHILTRADCTTRNQQRANRLRRAYEELEWRIDELASQEEIASLRPHLNGDQIMEVLGIGPGREVGQAYAFLLEHRTEHGPLPEDEAVELLRQWWADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJD2</accession>
    <name>A0A1Q2CJD2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">RPIT_12915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BlaI transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12915"/>
    <dbReference type="EnsemblBacteria" id="AQP46160">
        <property type="protein sequence ID" value="AQP46160"/>
        <property type="gene ID" value="RPIT_12915"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12915"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR34134">
        <property type="entry name" value="PTHR34134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03965">
        <property type="entry name" value="Penicillinase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="120" mass="13665" checksum="66DE9DB0407E549C" modified="2017-04-12" version="1">MGRMPSRGELEQRVMELLWASASPKTVAEVHQMLSEERELAYTTVMTVLDRLAKKNLVKRELVARAWQYVPRHSQAEVVTREMSMILDGLAPEVRVEALRRLSSRLQNEERAAMCGPSDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBI8</accession>
    <name>A0A1Q2CBI8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lipid kinase, YegS/Rv2252/BmrU family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_00420</name>
        <name evidence="5" type="ORF">SAMN05428934_10538</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY84442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00420"/>
    <dbReference type="EnsemblBacteria" id="AQP43467">
        <property type="protein sequence ID" value="AQP43467"/>
        <property type="gene ID" value="RPIT_00420"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY84442">
        <property type="protein sequence ID" value="SDY84442"/>
        <property type="gene ID" value="SAMN05428934_10538"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00420"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
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        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045540">
        <property type="entry name" value="YegS/DAGK_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19279">
        <property type="entry name" value="YegS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="DAGKc" evidence="3">
        <location>
            <begin position="206"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="508"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY84442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="537" mass="55223" checksum="275195A15F788747" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBJ0</accession>
    <name>A0A1Q2CBJ0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily/HAD-superfamily hydrolase, subfamily IIB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">HAD family hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00435</name>
        <name evidence="2" type="ORF">SAMN05428934_10541</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY84523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00435"/>
    <dbReference type="EnsemblBacteria" id="AQP43470">
        <property type="protein sequence ID" value="AQP43470"/>
        <property type="gene ID" value="RPIT_00435"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY84523">
        <property type="protein sequence ID" value="SDY84523"/>
        <property type="gene ID" value="SAMN05428934_10541"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00435"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY84523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="266" mass="28532" checksum="B25461D6A4A20049" modified="2017-04-12" version="1">MTFTPKLVALDIDGTLVDMDGVMPAPIRRAVRRVVDAGVPVVLATGRSWLGTEPVFDELDLPSGWAVSSNGAMVVTNPPLTIVHETRFDPAETIRRVSALAPNALIAVGDGLHWRASRHFPEGELLGRVKIESIEELAARPVSRVIVRDPETTEEAFAAMVEDLGLHEVSYFVGWSAWLDIAPMGVDKAHGLGIVCSELGIDPSDVLAIGDGRNDIEMLAWAGRGVAMGDAPDEVQAVADDVTGFFTDLGTVDELERWFPALAEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBK3</accession>
    <name>A0A1Q2CBK3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00555</name>
        <name evidence="3" type="ORF">SAMN05428934_10564</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY85123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43493">
        <property type="protein sequence ID" value="AQP43493"/>
        <property type="gene ID" value="RPIT_00555"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY85123">
        <property type="protein sequence ID" value="SDY85123"/>
        <property type="gene ID" value="SAMN05428934_10564"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00555"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY85123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="128" mass="13349" checksum="05079D725425D7E8" modified="2017-04-12" version="1">MNDTKTLYRASLAGSLGASALATILAALGLKNWALAMLGVATGGSVAASHLRMRLVGGQRRRDQRAEAARLSAIVTELERVRSSLDGSVGSAREHLEARLADVEAVIASTEGVILGELITHRDDSEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBL0</accession>
    <name>A0A1Q2CBL0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UDP-N-acetylglucosamine 2-epimerase (Non-hydrolyzing)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-N-acetylglucosamine 2-epimerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00545"/>
    <dbReference type="EnsemblBacteria" id="AQP43491">
        <property type="protein sequence ID" value="AQP43491"/>
        <property type="gene ID" value="RPIT_00545"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00545"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008761">
        <property type="term" value="F:UDP-N-acetylglucosamine 2-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003331">
        <property type="entry name" value="UDP_GlcNAc_Epimerase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029767">
        <property type="entry name" value="WecB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43174">
        <property type="entry name" value="PTHR43174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02350">
        <property type="entry name" value="Epimerase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00236">
        <property type="entry name" value="wecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase_2" evidence="2">
        <location>
            <begin position="19"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="376" mass="40876" checksum="C2AC72D9C6FDF04A" modified="2017-04-12" version="1">MVIYGTRPEAVKMAPLIRALEASEVLTPIVVSTGQHREMLDQVNKWFGITPDLDLGVFKAGQSLTELASRILDKLPEVLRDAQPDAVVVQGDTTTVAVGAIACFYHEIPVVHLEAGLRSGNLFSPFPEEANRRLAGQVTSLHLAPTTTSRDNLLREGIDPATIAVVGNTVIDALNWSAGESVEFEDERLAEASSAGRRMVLLTTHRRENWGEPMGDIGAAIAELARRYPETLFVFPAHKNPVVRDVLYPLLEGLENVVIVEPLDYPEFVHAQKWATLILTDSGGVQEEAPSFGKPVLVLRENTERPEAVVAGTVKLIGTDRQRIVDEAVRLLDDRAAYDAMSHAVNPYGDGNAAERSAAAIAQLLEVGERLPDFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBQ8</accession>
    <name>A0A1Q2CBQ8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_00845</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00845"/>
    <dbReference type="EnsemblBacteria" id="AQP43544">
        <property type="protein sequence ID" value="AQP43544"/>
        <property type="gene ID" value="RPIT_00845"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00845"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="14"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="301" mass="32156" checksum="5CE8222742DED5CF" modified="2017-04-12" version="1">MQRLRPGLVLSDRYRLIGHVASGGMGQVWEAFDDVLERRVAVKVMHPHTQDEIAMARRFKDEARFAAQLAHPNIVTVHDYVEHEGLICLVMEFVDGPTLAGILTRGPLEPEETRTVLAELAAGLAVAHDAGIIHRDIKPANVLVAETGAKLTDFGIARSVDRTSHTMDGQVLGTAHYLSPEQALGEQVGPPSDIYGLGVLAHEMLSGTKPFDRGSPIATALAHVQDAPPPLADGTPAELERLINSCLEKAPEDRPTAAALADLLAGSGVAVDVPADLPAEAPDVEETLVFSSVPRRALAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBX9</accession>
    <name>A0A1Q2CBX9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pyridoxal 5'-phosphate synthase subunit PdxS</fullName>
            <shortName evidence="3">PLP synthase subunit PdxS</shortName>
            <ecNumber evidence="3">4.3.3.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Pdx1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pdxS</name>
        <name evidence="6" type="ORF">RPIT_01225</name>
        <name evidence="7" type="ORF">SAMN05428934_105194</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = H(+) + 3 H2O + L-glutamate + phosphate + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:31507"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="4.3.3.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">In the presence of PdxT, forms a dodecamer of heterodimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the PdxS/SNZ family.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.6" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY88525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01225"/>
    <dbReference type="EnsemblBacteria" id="AQP43607">
        <property type="protein sequence ID" value="AQP43607"/>
        <property type="gene ID" value="RPIT_01225"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY88525">
        <property type="protein sequence ID" value="SDY88525"/>
        <property type="gene ID" value="SAMN05428934_105194"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01225"/>
    <dbReference type="UniPathway" id="UPA00245"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036381">
        <property type="term" value="F:pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04727">
        <property type="entry name" value="pdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01824">
        <property type="entry name" value="PdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001852">
        <property type="entry name" value="PdxS/SNZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033755">
        <property type="entry name" value="PdxS/SNZ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31829">
        <property type="entry name" value="PTHR31829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01680">
        <property type="entry name" value="SOR_SNZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029271">
        <property type="entry name" value="Pdx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00343">
        <property type="entry name" value="TIGR00343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01235">
        <property type="entry name" value="PDXS_SNZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51129">
        <property type="entry name" value="PDXS_SNZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0704">Schiff base</keyword>
    <feature type="domain" description="SOR_SNZ" evidence="5">
        <location>
            <begin position="13"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribose 5-phosphate binding" evidence="3">
        <location>
            <begin position="240"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with D-ribose 5-phosphate" evidence="3">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY88525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="299" mass="31558" checksum="6D602DDC6E3B11BA" modified="2017-04-12" version="1">MTQIIDTPQDRSLVNTGLAEMLKGGVIMDVVTPEQARIAEEAGAVAVMALERVPADIRAQGGVARMSDPDLIAGIIGAVSIPVMAKARIGHFVEAQVLEALGVDYIDESEVLSPADYVNHIDKTRFRVPFVCGATNLGEALRRITEGASMIRSKGEAGTGDVSEATRHLRTIRGEIRALAAKTDDELFVAAKDLQAPYELVRRVARDGKLPVVLFVAGGVATPADAAMMMQLGADGVFVGSGIFKSGDPAARARAIVQATTHFDDAARIAEVSRGLGEAMVGINVADVPAPHRLAERGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBY1</accession>
    <name>A0A1Q2CBY1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Malate dehydrogenase (Oxaloacetate-decarboxylating)</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">NAD-dependent malic enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_01250</name>
        <name evidence="8" type="ORF">SAMN05428934_105199</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the malic enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY88658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01250"/>
    <dbReference type="EnsemblBacteria" id="AQP43611">
        <property type="protein sequence ID" value="AQP43611"/>
        <property type="gene ID" value="RPIT_01250"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY88658">
        <property type="protein sequence ID" value="SDY88658"/>
        <property type="gene ID" value="SAMN05428934_105199"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01250"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00072">
        <property type="entry name" value="MALOXRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="malic" evidence="6">
        <location>
            <begin position="89"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Malic_M" evidence="5">
        <location>
            <begin position="281"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY88658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="573" mass="62552" checksum="FD16C3D8C7028E64" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC07</accession>
    <name>A0A1Q2CC07_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_01460</name>
        <name evidence="2" type="ORF">SAMN05428934_10840</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43644">
        <property type="protein sequence ID" value="AQP43644"/>
        <property type="gene ID" value="RPIT_01460"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01704">
        <property type="protein sequence ID" value="SDZ01704"/>
        <property type="gene ID" value="SAMN05428934_10840"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01460"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="SSF55154"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ01704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="460" mass="50024" checksum="71A42645532B5F80" modified="2017-04-12" version="1">MGKKVKGALRLDVPFSSDAPQLTSGAVGLPRIVKHPGQSCEVTVTVLDAPDARLQRAGVTVAHRVVDGRGEWLLSAPGWGPALPESRVEPVGASGDLPDDFTRLIRPILRRGVLGTLATLELERDEWALRSEEGEDAALVRDERVTVTRSGMITSRYREIEITPTGLLTGQQREFLLSSGLAVGATVVDAFPSAQSRIGAPATGLTSFPRPRDPGPDATLEEYVSAVFTRHLDQIVRAELARRAGDGDVAHVDALLWAFGRDLRGLASVLEPSWREDIERALDGLPFTSPADIEAPVLDVIEALVGAARAPQLGDLAHEPAARVLFDKAEQATVILAERCRGLAVDSPDEVWHGALRAAEQLEVVLEVAAPVLPKGRDRMARMLGEVTEGLRRGALGAFVGDPELDGLSAAQAYQLGRETERKRAGIADVRQEFVDRWPELFREARKLVDKARRRRERKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC36</accession>
    <name>A0A1Q2CC36_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA(Ile)-lysidine synthase</fullName>
            <ecNumber evidence="6">6.3.4.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">tRNA(Ile)-2-lysyl-cytidine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA(Ile)-lysidine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tilS</name>
        <name evidence="9" type="ORF">RPIT_01555</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + cytidine(34) in tRNA(Ile2) + L-lysine = AMP + diphosphate + H(+) + lysidine(34) in tRNA(Ile2)</text>
            <dbReference type="Rhea" id="RHEA:43744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10670"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83665"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.19"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the tRNA(Ile)-lysidine synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.19" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01555"/>
    <dbReference type="EnsemblBacteria" id="AQP43660">
        <property type="protein sequence ID" value="AQP43660"/>
        <property type="gene ID" value="RPIT_01555"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01555"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01992">
        <property type="entry name" value="PP-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01161">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012795">
        <property type="entry name" value="tRNA_Ile_lys_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015262">
        <property type="entry name" value="tRNA_Ile_lys_synt_subst-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="PTHR43033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09179">
        <property type="entry name" value="TilS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02432">
        <property type="entry name" value="lysidine_TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="ATP_bind_3" evidence="7">
        <location>
            <begin position="27"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="TilS" evidence="8">
        <location>
            <begin position="241"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="31"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP43660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="321" mass="33935" checksum="B292882C7B3F03BB" modified="2017-04-12" version="1">MARRELGPAALRVGRAVADHLPDGGAVVGCSGGADSLALALGAAWAAARTGADVAAVVVDHGLRPDSGHVSSRVVEQLRGRGLDARVVRVQVEPDHPDGLEAAARHARLATLEATGRPVLLGHTLDDQAETVLLGLLRGSGTRSLAGMAAVRGPFIRPLLGLRRADTEAACGEWGIEPWQDPMNDDERYARVRTRRLLPLLTDELGRDVAPALARTARLARADADHLDALALAAVPQRQWLEVADLEPLPDALLWRVVRRWLAARSPSSGMEHVLAVARLVGHWHGQGPVAVPGAVVRRVGGRLLVEPSGAARQDDGDPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC37</accession>
    <name>A0A1Q2CC37_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">DNA repair protein RadA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">radA</name>
        <name evidence="8" type="ORF">RPIT_01655</name>
        <name evidence="9" type="ORF">SAMN05428934_10880</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.</text>
    </comment>
    <comment type="domain">
        <text evidence="5">The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the RecA family. RadA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01655"/>
    <dbReference type="EnsemblBacteria" id="AQP43674">
        <property type="protein sequence ID" value="AQP43674"/>
        <property type="gene ID" value="RPIT_01655"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02429">
        <property type="protein sequence ID" value="SDZ02429"/>
        <property type="gene ID" value="SAMN05428934_10880"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01655"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000725">
        <property type="term" value="P:recombinational repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01498">
        <property type="entry name" value="RadA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004504">
        <property type="entry name" value="DNA_repair_RadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041166">
        <property type="entry name" value="Rubredoxin_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18073">
        <property type="entry name" value="Rubredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00416">
        <property type="entry name" value="sms"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0346">Stress response</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RECA_2" evidence="7">
        <location>
            <begin position="63"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Lon-protease-like" evidence="5">
        <location>
            <begin position="349"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="RadA KNRFG motif" evidence="5">
        <location>
            <begin position="249"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="92"/>
            <end position="99"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP43674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ02429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="461" mass="48919" checksum="E4881C94677A6EB9" modified="2017-04-12" version="1">MAKKQDSYQCTECGWVSTRWVGRCGECQAWGTVAERGAPKLRQVASSVPADKAVPISDVATDKAQRRRTTIAELDRVLGDGLVPGAVVLLAGEPGVGKSTLLLDVAAKWARSGQTTLYISGEESASQVRLRAERTSALDDKLYLASETDLGTVLGHIEQVRPSLLVLDSVQTIATADAEGAPGGPAQVREVTGALARVAKREDMAVVIVGHVTKDGSIAGPRTLEHLVDVVLTFEGDRHSGFRMVRATKNRFGPADEVGCFEMSERGIVEVPDPSGLFTTAHSEPTPGTCVTVTLEGRRPLLAEIQALVAQSPNQSSPRRTTHGLDSSRIAMVLAVLERKANLPLSSHDVYVSTVGGARVTDPSVDLPVAVAVASAALDRHFPKKLLALGEVGLAGDLRRVPGVERRLAEASRLGFELAVVPRGSRDVTVKVPKLGGLKVVEVETLADALGMLDLRRAARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC42</accession>
    <name>A0A1Q2CC42_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ATP-dependent Clp protease ATP-binding subunit ClpC</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="12">NDP-hexose 4-ketoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_01615</name>
        <name evidence="13" type="ORF">SAMN05428934_10871</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Homohexamer. The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01615"/>
    <dbReference type="EnsemblBacteria" id="AQP43667">
        <property type="protein sequence ID" value="AQP43667"/>
        <property type="gene ID" value="RPIT_01615"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02277">
        <property type="protein sequence ID" value="SDZ02277"/>
        <property type="gene ID" value="SAMN05428934_10871"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01615"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Clp R" evidence="11">
        <location>
            <begin position="2"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="10">
        <location>
            <begin position="422"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP43667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDZ02277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="836" mass="92424" checksum="8177F42ED79D6ADA" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCD0</accession>
    <name>A0A1Q2CCD0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_02210</name>
        <name evidence="4" type="ORF">SAMN05428934_10141</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY23540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43772">
        <property type="protein sequence ID" value="AQP43772"/>
        <property type="gene ID" value="RPIT_02210"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY23540">
        <property type="protein sequence ID" value="SDY23540"/>
        <property type="gene ID" value="SAMN05428934_10141"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02210"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544415" evidence="2">
        <location>
            <begin position="29"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY23540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="179" mass="18720" checksum="51CCCEBD996FEB35" modified="2017-04-12" version="1">MTPPPTRLLTAVLAALLLAGCSDTPTQAPTPHSTTPASHPVTSPASVGESDPAEGWVGADELDTTQPSMEADRHDPPEDAQIASAVTAATAFVVGWLTADQQLRRQRLEGVAAEALIAAFDDPRFTPAAGTQHGPAHVVEADQMQITTRHRLDTGTVVDVTLILDPDSTHGWIAIAITP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCE3</accession>
    <name>A0A1Q2CCE3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphoribosylamine--glycine ligase</fullName>
            <ecNumber evidence="6">6.3.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">GARS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Glycinamide ribonucleotide synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phosphoribosylglycinamide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">purD</name>
        <name evidence="9" type="ORF">RPIT_01905</name>
        <name evidence="10" type="ORF">SAMN05428934_108129</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)-(5-phospho-beta-D-ribosyl)glycinamide + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17453"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the GARS family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.13" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ03424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01905"/>
    <dbReference type="EnsemblBacteria" id="AQP43715">
        <property type="protein sequence ID" value="AQP43715"/>
        <property type="gene ID" value="RPIT_01905"/>
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    <dbReference type="EnsemblBacteria" id="SDZ03424">
        <property type="protein sequence ID" value="SDZ03424"/>
        <property type="gene ID" value="SAMN05428934_108129"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01905"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004637">
        <property type="term" value="F:phosphoribosylamine-glycine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00138">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020561">
        <property type="entry name" value="PRibGlycinamid_synth_ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000115">
        <property type="entry name" value="PRibGlycinamide_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020560">
        <property type="entry name" value="PRibGlycinamide_synth_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037123">
        <property type="entry name" value="PRibGlycinamide_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020559">
        <property type="entry name" value="PRibGlycinamide_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020562">
        <property type="entry name" value="PRibGlycinamide_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43472">
        <property type="entry name" value="PTHR43472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01071">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02843">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02844">
        <property type="entry name" value="GARS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01210">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00877">
        <property type="entry name" value="purD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00184">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="8">
        <location>
            <begin position="107"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP43715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ03424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="408" mass="42419" checksum="09B313E9C90D8613" modified="2017-04-12" version="1">MKILLLGSGGREHAIGRALAHDPAVTELHVAPGNPGLSSIATMHSADPASPTAVLDLARSLQVDLIVIGPEAPLVAGVADALRDAGFDVFGPGREAAVLEGSKAFAKEVMRSAGVPTADARVCETPDEVSAALDEFGPPYVVKNDGLAAGKGVVVTTDRQEALDHAASCGRVVIEDFLDGPEVSLFAICDGERALPLLPAQDYKRVGDDDEGPNTGGMGAYCPLSWADAGLTDQIMSEVVNPTLAEMRRRGTPFIGLLYAGLALTSRGLRVVEFNVRFGDPETQAVLSLLKTPLAGVLRAAARGELDSVPELDWHDGAAVVVVSAAEGYPGTPATGRPITLPDDETDAYVLHAGTRIEGGRLVSSGGRVLGIVGRGADLDEARRLAYALLERIDFAGGFSRTDIGVPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCF4</accession>
    <name>A0A1Q2CCF4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_02270</name>
        <name evidence="2" type="ORF">SAMN05428934_10153</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY23883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43784">
        <property type="protein sequence ID" value="AQP43784"/>
        <property type="gene ID" value="RPIT_02270"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY23883">
        <property type="protein sequence ID" value="SDY23883"/>
        <property type="gene ID" value="SAMN05428934_10153"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02270"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY23883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="110" mass="12305" checksum="17E6E6FA7CCC8043" modified="2017-04-12" version="1">MATRRRQPLVTRDDVPLPPYEWSHDRSGSKSAWGVNLPISERHDLQLMAQRGTAGRWTWTLTIYRTGSTDQVTRIACGVQPTLTAAKPAAEAAARIWLADQLELPDESHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCG2</accession>
    <name>A0A1Q2CCG2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_02305</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02305"/>
    <dbReference type="EnsemblBacteria" id="AQP43791">
        <property type="protein sequence ID" value="AQP43791"/>
        <property type="gene ID" value="RPIT_02305"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02305"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="250" mass="27454" checksum="41D07458CA11A5B5" modified="2017-04-12" version="1">MLRFEDVTYSYARRRAPVLRNFTYEFPSGRSVLLGPNGAGKSTLMSLAVGWRTPQAGTVSLGPDVGPKRSASRRAHALAPGTVGFMPQDIRHLPGLTVIEQVRYAGWLKGMRQRDTEAKSRELLCRLGLEDKMADSAKNLSGGQLRRMGLAMAMVHEPKVLILDEPTAGLDPAQRSNFRELIAQVSDSEMIISTHQVDDIQAIYSNVAVLLSGQVVWEGTPREFVSLAPEGPHQAELAFKVVMKQEGLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCH1</accession>
    <name>A0A1Q2CCH1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02485</name>
        <name evidence="3" type="ORF">SAMN05428934_10196</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY25128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02485"/>
    <dbReference type="EnsemblBacteria" id="AQP43823">
        <property type="protein sequence ID" value="AQP43823"/>
        <property type="gene ID" value="RPIT_02485"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY25128">
        <property type="protein sequence ID" value="SDY25128"/>
        <property type="gene ID" value="SAMN05428934_10196"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02485"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="SSF52029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY25128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="210" mass="21848" checksum="FF33E923E2120C26" modified="2017-04-12" version="1">MPAWGWFLVALAVGSALLAVAVTVDVRARRRAGGVGEPAPRRGIDAVDAQVPRYVTQDDVDALPSPGRGRPREPGHPGEGFSFGHAHADFGTNPDGAALTNPQILVVDGEVSSMRELLGPLSAATEALPLVVVADGFHPEVIATLAANRRALAFPVVAAVAGARDRTRLAELTGAEVLSPADLRAGYVPATALGSARRWTSTPTRAWVQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCI9</accession>
    <name>A0A1Q2CCI9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Multifunctional fusion protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="9">Glycine--tRNA ligase beta subunit</fullName>
                <ecNumber evidence="9">6.1.1.14</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="9">Glycyl-tRNA synthetase beta subunit</fullName>
                <shortName evidence="9">GlyRS</shortName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="8">Glycine--tRNA ligase alpha subunit</fullName>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">Glycyl-tRNA synthetase alpha subunit</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="8" type="primary">glyQ</name>
        <name evidence="9" type="synonym">glyS</name>
        <name evidence="10" type="ORF">RPIT_02540</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)</text>
            <dbReference type="Rhea" id="RHEA:16013"/>
            <dbReference type="Rhea" id="RHEA-COMP:9664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9683"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.14"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02540"/>
    <dbReference type="EnsemblBacteria" id="AQP43832">
        <property type="protein sequence ID" value="AQP43832"/>
        <property type="gene ID" value="RPIT_02540"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02540"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00254">
        <property type="entry name" value="Gly_tRNA_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00255">
        <property type="entry name" value="Gly_tRNA_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015944">
        <property type="entry name" value="Gly-tRNA-synth_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006194">
        <property type="entry name" value="Gly-tRNA-synth_heterodimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002310">
        <property type="entry name" value="Gly-tRNA_ligase_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30075">
        <property type="entry name" value="PTHR30075"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02091">
        <property type="entry name" value="tRNA-synt_2e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02092">
        <property type="entry name" value="tRNA_synt_2f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01044">
        <property type="entry name" value="TRNASYNTHGA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00388">
        <property type="entry name" value="glyQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00211">
        <property type="entry name" value="glyS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50861">
        <property type="entry name" value="AA_TRNA_LIGASE_II_GLYAB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP43832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="1019" mass="110175" checksum="915B514354DC4E79" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCJ0</accession>
    <name>A0A1Q2CCJ0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Putative ABC transport system ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_02350</name>
        <name evidence="6" type="ORF">SAMN05428934_10170</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY24384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02350"/>
    <dbReference type="EnsemblBacteria" id="AQP43800">
        <property type="protein sequence ID" value="AQP43800"/>
        <property type="gene ID" value="RPIT_02350"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY24384">
        <property type="protein sequence ID" value="SDY24384"/>
        <property type="gene ID" value="SAMN05428934_10170"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02350"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="7"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY24384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="236" mass="24937" checksum="C7E678DCD7FBB479" modified="2017-04-12" version="1">MTGLARVAGRGLVRTFGAGATAVHALAGVDIEGHASELTVVTGPSGSGKTTLLNLLGGLDRPTAGHVVLDDGRVLSELPEAEVLATRRARIGYVFQSFGLIPVLSAAENVEVPLRLALTDPRERDERVATMLERVGLARHARQRPYELSGGQQQRVGVARALVGRPDILIADEPTGQLDSDTAATIMDLIVHLTHELGIATIVSTHDPLLIERADRVLRLHDGVVDANGGGRTPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCL7</accession>
    <name>A0A1Q2CCL7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RecB family nuclease, putative, TM0106 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02590</name>
        <name evidence="3" type="ORF">SAMN05428934_101118</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY25815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02590"/>
    <dbReference type="EnsemblBacteria" id="AQP43841">
        <property type="protein sequence ID" value="AQP43841"/>
        <property type="gene ID" value="RPIT_02590"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY25815">
        <property type="protein sequence ID" value="SDY25815"/>
        <property type="gene ID" value="SAMN05428934_101118"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02590"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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            <end position="558"/>
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</entry>
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</entry>
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            </authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Peterson S.W."/>
            </authorList>
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        </source>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
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    </evidence>
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            <dbReference type="Proteomes" id="UP000199635"/>
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    </evidence>
    <sequence length="607" mass="66393" checksum="821467240420F1F8" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
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            <fullName evidence="1">Inositol 2-dehydrogenase</fullName>
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        <alternativeName>
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    </protein>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>myo-inositol + NAD(+) = H(+) + NADH + scyllo-inosose</text>
            <dbReference type="Rhea" id="RHEA:16949"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:17811"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.18"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.18" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03310"/>
    <dbReference type="EnsemblBacteria" id="AQP43962">
        <property type="protein sequence ID" value="AQP43962"/>
        <property type="gene ID" value="RPIT_03310"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30209">
        <property type="protein sequence ID" value="SDY30209"/>
        <property type="gene ID" value="SAMN05428934_101263"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03310"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050112">
        <property type="term" value="F:inositol 2-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019310">
        <property type="term" value="P:inositol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01671">
        <property type="entry name" value="IolG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023794">
        <property type="entry name" value="MI/DCI_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="2">
        <location>
            <begin position="3"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="3">
        <location>
            <begin position="135"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY30209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="334" mass="36692" checksum="398210FC6C963B92" modified="2017-04-12" version="1">MTLRIGMIGPGGMGRAHIERIHSVISGGRVVGVSDVNADNARAVAEQIGGTAFDSSTDLINSPDIDAIMITSHGPAHEPDVIAAIEAGKYVFCEKPLAPTAEACVRIMEAEQKAGRKLVTVGFMRRFDASYREMKQIIDDGEIGEPLMVNCAHRNPTVPEFYTWDMAINDTAIHEIDTMRWLLGEEFVSARVDKPKKTSLRFEHLQDPLVLILYTESGVRVSDEVFVNCQYGYDIQCEVVAETGAVRLSDQELVQRADKLGRRNRLTMDHNQRFGGAFVTEVQEWITAVTEDRHTGSSSWDGYAAAVVCDAGVQALTADGEVPISMMDKPALYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCW7</accession>
    <name>A0A1Q2CCW7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsE</name>
        <name evidence="12" type="ORF">RPIT_03175</name>
        <name evidence="13" type="ORF">SAMN05428934_101236</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.</text>
    </comment>
    <comment type="function">
        <text evidence="7">With S4 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 9">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03175"/>
    <dbReference type="EnsemblBacteria" id="AQP43941">
        <property type="protein sequence ID" value="AQP43941"/>
        <property type="gene ID" value="RPIT_03175"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29405">
        <property type="protein sequence ID" value="SDY29405"/>
        <property type="gene ID" value="SAMN05428934_101236"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03175"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01307_B">
        <property type="entry name" value="Ribosomal_S5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_S5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005712">
        <property type="entry name" value="Ribosomal_S5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_S5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_S5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018192">
        <property type="entry name" value="Ribosomal_S5_N_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="PTHR13718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01021">
        <property type="entry name" value="rpsE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00585">
        <property type="entry name" value="RIBOSOMAL_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S5 DRBM" evidence="11">
        <location>
            <begin position="33"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="10"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP43941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY29405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="201" mass="21187" checksum="303B0B1802AB103E" modified="2017-04-12" version="1">MSETQQRRGSGAGGERRGRDDRRGQAPKEESKYLERVVTINRVAKVVQGGRRFSFTALVVVGDGEGMVGVGYGKAKEVPAAIAKGVEEAKKHFFRVPLIQRTIPHPVQGEKAAGVVLLRPASPGTGVIAGGSARAVLECAGVHDVLAKSLGSANAINVVHATVDALKQLEEPAAVAKRRGLPVEDVVPSFLLRAQKEEVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCX2</accession>
    <name>A0A1Q2CCX2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DeoR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, DeoR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_03265</name>
        <name evidence="6" type="ORF">SAMN05428934_101254</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03265"/>
    <dbReference type="EnsemblBacteria" id="AQP43954">
        <property type="protein sequence ID" value="AQP43954"/>
        <property type="gene ID" value="RPIT_03265"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29935">
        <property type="protein sequence ID" value="SDY29935"/>
        <property type="gene ID" value="SAMN05428934_101254"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03265"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014036">
        <property type="entry name" value="DeoR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018356">
        <property type="entry name" value="Tscrpt_reg_HTH_DeoR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00455">
        <property type="entry name" value="DeoRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00037">
        <property type="entry name" value="HTHLACR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00420">
        <property type="entry name" value="HTH_DEOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00894">
        <property type="entry name" value="HTH_DEOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY29935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="256" mass="27468" checksum="4166DEB592C8FD76" modified="2017-04-12" version="1">MLTDVRHQRIADWVRREGSVSVLGVADAFGVSEATARRDLDQLASTGVVERIRGGARALRRPIRPEADASEFAVVAAQESDEKRAIAKRAAALVHDGDVVALDIGTTVFAMCEHLKERSITVVTASLAVVRALSDAPHMDIVVMGGVLRPNYDSLVGVLTESCLRQVRVDIAFLGAAGIHADGAVIDSTPSEVPVKRAMIDVARKAWLLADHQKFPGMGFLQVVPIDRFAGLITDRPPSSAQLRLPPDSTLEVLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCX9</accession>
    <name>A0A1Q2CCX9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7 8">Elongation factor Tu</fullName>
            <shortName evidence="7">EF-Tu</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tuf</name>
        <name evidence="10" type="ORF">RPIT_02985</name>
        <name evidence="11" type="ORF">SAMN05428934_101198</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY28177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02985"/>
    <dbReference type="EnsemblBacteria" id="AQP43905">
        <property type="protein sequence ID" value="AQP43905"/>
        <property type="gene ID" value="RPIT_02985"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY28177">
        <property type="protein sequence ID" value="SDY28177"/>
        <property type="gene ID" value="SAMN05428934_101198"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02985"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_B">
        <property type="entry name" value="EF_Tu_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="10"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="19"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="83"/>
            <end position="87"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="138"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP43905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY28177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="397" mass="43872" checksum="08CF3CA182E34D12" modified="2017-04-12" version="1">MAKAKFERTKPHCNIGTIGHVDHGKTTLTAAITKVLHDRYPEWNAVSAFDQIDKAPEERQRGITISIAHVEYQTEKRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMAQTHEHILLARQVGVPAMVVALNKCDMIDEGDADLIDLVEMELDEILSAQGFEDTKIVRVAAFPALQGDEKWADTIMDLMNAVDEYIPQPERDTDKPFLMPVEDVFTITGRGTVITGRIERGIVRTGDTVDIVGIREEKQSSTVTGVEMFRKILDEGRAGENVGLLLRGTKKEDVERGMVVIKPGSTTPHTDFEANVYVLDKNEGGRHKPFFSNYSPQFYFRTTDVTGVVQLPEGTEMVMPGDNTEMTVHLNKPIAMEENLKFAIREGGRTVGAGNVTKILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCY0</accession>
    <name>A0A1Q2CCY0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">General stress protein 26</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03275</name>
        <name evidence="3" type="ORF">SAMN05428934_101256</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03275"/>
    <dbReference type="EnsemblBacteria" id="AQP43956">
        <property type="protein sequence ID" value="AQP43956"/>
        <property type="gene ID" value="RPIT_03275"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29992">
        <property type="protein sequence ID" value="SDY29992"/>
        <property type="gene ID" value="SAMN05428934_101256"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03275"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038725">
        <property type="entry name" value="YdaG_split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16242">
        <property type="entry name" value="Pyrid_ox_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyrid_ox_like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY29992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="159" mass="17013" checksum="E180FCBC7E7175D2" modified="2017-04-12" version="1">MNEQKTLNDVIDLISKQKVGMLTTHEGDRLVSRPMGMQDPDRDGTLWFFAKADSDVAHQVGADPRVNVSLADGDYLSVTGTAAVVNDVAKKRELWDASVEAFMQTDPEDPQAVLIKVAADSIAYWDTPSAVGSVFAMVKGMVGDSEPDAGESGVVEAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCY5</accession>
    <name>A0A1Q2CCY5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glutathione-dependent formaldehyde dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Threonine dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_03280</name>
        <name evidence="7" type="ORF">SAMN05428934_101257</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03280"/>
    <dbReference type="EnsemblBacteria" id="AQP43957">
        <property type="protein sequence ID" value="AQP43957"/>
        <property type="gene ID" value="RPIT_03280"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30020">
        <property type="protein sequence ID" value="SDY30020"/>
        <property type="gene ID" value="SAMN05428934_101257"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03280"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027399">
        <property type="entry name" value="ADH_N_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13823">
        <property type="entry name" value="ADH_N_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ADH_N_assoc" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="domain" description="ADH_N" evidence="4">
        <location>
            <begin position="26"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="ADH_zinc_N" evidence="3">
        <location>
            <begin position="189"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY30020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="393" mass="41845" checksum="E7AE85A2AFF36B11" modified="2017-04-12" version="1">MRALTWHGIEDVRVQDVPEPALLAPTDAIVRVTSTAICGSDLHLYGVLAPFLTRGDVLGHEFMGIVTEVGDAVTTIAPGDRVVVPFTIACGACWMCRRGLHAQCETTQVREHGKGAALFGYTSLYGQVPGGQAELVRVPHADVGPVKVPEGTPDERFLFLSDILPTAWQGIRWADVEQGSTVAILGLGPVGQLAVTCARRQGAGRVIGVDLVPERLERAGANGAEVVDVTAVDDVAATLREMTDGRGPDSVVDAVGMEAHGSPVAERVIKMAARLPKPLGRGAIEHAGIDRLAALHTAIDAVRRGGTVSLSGVYGGALDPMPLMDMFDKGITMRMGQCHVQRWTGELLDILTHGDPFGVDDLVTHRLPLEEAPEAYAMFQEKRDGCIKVVLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD49</accession>
    <name>A0A1Q2CD49_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Anthranilate phosphoribosyltransferase</fullName>
            <ecNumber evidence="3">2.4.2.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">trpD</name>
        <name evidence="6" type="ORF">RPIT_03735</name>
        <name evidence="7" type="ORF">SAMN05428934_101349</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>diphosphate + N-(5-phospho-beta-D-ribosyl)anthranilate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate</text>
            <dbReference type="Rhea" id="RHEA:11768"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="3">Binds 2 magnesium ions per monomer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the anthranilate phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.18" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY32764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03735"/>
    <dbReference type="EnsemblBacteria" id="AQP44034">
        <property type="protein sequence ID" value="AQP44034"/>
        <property type="gene ID" value="RPIT_03735"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY32764">
        <property type="protein sequence ID" value="SDY32764"/>
        <property type="gene ID" value="SAMN05428934_101349"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03735"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00041"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004048">
        <property type="term" value="F:anthranilate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00211">
        <property type="entry name" value="TrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005940">
        <property type="entry name" value="Anthranilate_Pribosyl_Tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036320">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285">
        <property type="entry name" value="PTHR43285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="SSF47648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="SSF52418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01245">
        <property type="entry name" value="trpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="1 3 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Glycos_trans_3N" evidence="5">
        <location>
            <begin position="8"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_3" evidence="4">
        <location>
            <begin position="76"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="3">
        <location>
            <begin position="86"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="3">
        <location>
            <begin position="93"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="3">
        <location>
            <begin position="111"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>anthranilate</name>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY32764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="345" mass="35957" checksum="E731256E7DCAB3A5" modified="2017-04-12" version="1">MSGYTWPDILTGLVRREGLEATAATWALNEIFAGRASDVQIAAMLTALRAKGESEDEISGLADAMLANAMPIALDPDAVDVVGTGGDRANTVNISTMAAIVAAGAGAKVVKHGSRAASSQSGTADTLEALGVRIDLEPNRQATVLDEAGIVFLFAQHYHPAMRNVAGVRKALGIQTTFNFIGPLANPAQPRAMALGVANDAVAPVIARVLAERGTRGMVFRGFDGLDELTTTSSSDVWMIAEGRVHRTTLDPVDLDLEPAAPHDLAGGEPAHNAQVARDTMNGKAGPVRDIVVLNAAAALLSYRGISTVEPLVDQLRGPLKAAQEAIDSGRAATTLETWVAATQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD56</accession>
    <name>A0A1Q2CD56_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pirin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_03695</name>
        <name evidence="7" type="ORF">SAMN05428934_101341</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY32562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03695"/>
    <dbReference type="EnsemblBacteria" id="AQP44027">
        <property type="protein sequence ID" value="AQP44027"/>
        <property type="gene ID" value="RPIT_03695"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY32562">
        <property type="protein sequence ID" value="SDY32562"/>
        <property type="gene ID" value="SAMN05428934_101341"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03695"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008778">
        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903">
        <property type="entry name" value="PTHR13903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05726">
        <property type="entry name" value="Pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin" evidence="4">
        <location>
            <begin position="42"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin_C" evidence="5">
        <location>
            <begin position="193"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY32562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="333" mass="37225" checksum="A755BC34F614742B" modified="2017-04-12" version="1">MSNIESSPQVMECGHEPHPPSEVQRLEPRLVSLGEGADSMTVRRTIPQLERSFVGAWCFADHYGPNLVEATGGMDVAPHPHTSLQTVSWLFDGEIEHRDSGGIHELVRPGEVNLMTSGFGISHSEVTTDQTEYLHGVQLWVVLPEHAKNMEREFQHFRPEPVDVDGGTAKVLVGTLEEGVSPIHTETPLLGAEIVLRPGAIWEFEVNTGFEHGVLVDSGSIEMDGVLIDKDSMGVRDAGLGNLRLSNPTDREARIMLLGGEPFDEGIVMWWNFIGRSHEEIVELRDAWQRDDDRFGGVRGYRGQLRRLEAPPLPSMRLKPRYRRRRGGRGHQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD58</accession>
    <name>A0A1Q2CD58_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Cytochrome bc1 complex cytochrome c subunit</fullName>
            <ecNumber evidence="3 10">7.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">RPIT_03715</name>
        <name evidence="16" type="ORF">SAMN05428934_101345</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1T</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1</strain>
        </source>
    </reference>
    <reference evidence="15" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:11484"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="7.1.1.8"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cell membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">Binds 2 heme groups covalently per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.8" evidence="3 10"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY32659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03715"/>
    <dbReference type="EnsemblBacteria" id="AQP44031">
        <property type="protein sequence ID" value="AQP44031"/>
        <property type="gene ID" value="RPIT_03715"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY32659">
        <property type="protein sequence ID" value="SDY32659"/>
        <property type="gene ID" value="SAMN05428934_101345"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03715"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008121">
        <property type="term" value="F:ubiquinol-cytochrome-c reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009152">
        <property type="entry name" value="bc1_cytC-su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000007">
        <property type="entry name" value="Ubiq_cycred_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 10 11" id="KW-0349">Heme</keyword>
    <keyword evidence="8 10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="15" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="7 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544426" description="Cytochrome bc1 complex cytochrome c subunit" evidence="13">
        <location>
            <begin position="40"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="14">
        <location>
            <begin position="45"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="14">
        <location>
            <begin position="146"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="11">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="11">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="11">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="11">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000007-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000007-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="AQP44031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="SDY32659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="269" mass="27982" checksum="1BBF3BE1DDE600B7" modified="2017-04-12" version="1">MQIFSTLRRHGAARPLLLILALLLVGLSYSAVSPQRSSAETEMTQQIEEGKALFDFTCSSCHGLGGEGTSQGPSLIGVGAASVDFQMGTGRMPAARQEAQLPARKVNYTQEQIEAVAAYVATLGPGPGIPAESAYTLSLEGDEKAEAIARGGALFRANCSACHGIVGGGGAMPNGKFAPSLAETSDVHIYEAVRTGPQQMPLFSKEVMPDESVAEIIAYLNGAEEQANYGGITMGDAGPVSEGFWAFIIGIGGFALIATWIAKKGARAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD97</accession>
    <name>A0A1Q2CD97_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl transferase family 1</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Glycosyltransferase involved in cell wall bisynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_03915</name>
        <name evidence="6" type="ORF">SAMN05428934_101387</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY33744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03915"/>
    <dbReference type="EnsemblBacteria" id="AQP44067">
        <property type="protein sequence ID" value="AQP44067"/>
        <property type="gene ID" value="RPIT_03915"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY33744">
        <property type="protein sequence ID" value="SDY33744"/>
        <property type="gene ID" value="SAMN05428934_101387"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03915"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="4">
        <location>
            <begin position="19"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="368"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY33744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="394" mass="41430" checksum="A421D3BBA920A159" modified="2017-04-12" version="1">MRIAYVSVDPGIPVFGTKGASVHIQEVVRELIARGHDVTVYATRIGDDVPADLADLRVVPVKVAKGDPAARERAQQDASAEMVTRILADGADLVYERYSLFSTVLARVTAASDAVGVLEVNAPLIDEQKKHRDMVDENGAWAALRAQVHAAAATICVSDPVSAWVRRHTDGDRVHTVANGVSVTRILPQPEDDDVVVTFVGTLKPWHGTSVLIDAAGMAREPWTVRVVGDGPERAALEAQAARLGVDVDFRGAVAPEEMPAHLAGSAIGVAPYPASVEDGDQYFSPLKVYEYLAAGLPVVASSVGQLPGIITDEGVLVAPSDPAALARALDRLAADPESRRAMGAKARERAVSDHSWSGVVDSILGLALSEGDGGPSSPLAPSSPARLRDQHDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDE1</accession>
    <name>A0A1Q2CDE1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Triosephosphate isomerase</fullName>
            <shortName evidence="3">TIM</shortName>
            <shortName evidence="3">TPI</shortName>
            <ecNumber evidence="3 4">5.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Triose-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tpiA</name>
        <name evidence="5" type="ORF">RPIT_04220</name>
        <name evidence="6" type="ORF">SAMN05428934_101448</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="3 4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY35582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04220"/>
    <dbReference type="EnsemblBacteria" id="AQP44116">
        <property type="protein sequence ID" value="AQP44116"/>
        <property type="gene ID" value="RPIT_04220"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY35582">
        <property type="protein sequence ID" value="SDY35582"/>
        <property type="gene ID" value="SAMN05428934_101448"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04220"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00189"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020861">
        <property type="entry name" value="Triosephosphate_isomerase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="PTHR21139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="SSF51351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00171">
        <property type="entry name" value="TIM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3 4" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="3 4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="2 3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="10"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="241"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="active site" description="Electrophile" evidence="3">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY35582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="259" mass="28078" checksum="55F62A8CDD588B3D" modified="2017-04-12" version="1">MTRKPIMAGNWKMNVDHIEATGLVEKLHYTLVDKEWDPKKSDAVLCVPFTDLRTVKTLIDGDRLHFGLGAQNVSQHDNGAYTGEISTAMLSKLGVQYVIVGHSERREYYGETDEIINAKAKKVLAAGMTPIICVGEGLDIRKAGEHVEYTLNQVRGTLADLSAEQVAGLVIAYEPVWAIGTGEVATPDDAQEVCGAIRREVAALYDEPTAESVRIQYGGSVKSGNVAQIMSQPDIDGALVGGASLQPDEFAAIVRFYQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDF4</accession>
    <name>A0A1Q2CDF4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SURF1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_04420</name>
        <name evidence="6" type="ORF">SAMN05428934_101490</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SURF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY36662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04420"/>
    <dbReference type="EnsemblBacteria" id="AQP44152">
        <property type="protein sequence ID" value="AQP44152"/>
        <property type="gene ID" value="RPIT_04420"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY36662">
        <property type="protein sequence ID" value="SDY36662"/>
        <property type="gene ID" value="SAMN05428934_101490"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04420"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06662">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002994">
        <property type="entry name" value="Surf1/Shy1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045214">
        <property type="entry name" value="Surf1/Surf4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427">
        <property type="entry name" value="PTHR23427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02104">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50895">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY36662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="251" mass="27470" checksum="0AE4F8BF9CA2F7E4" modified="2017-04-12" version="1">MSRQVRRWVAMGVLGAVLATAFVLLGRWQLDRLDERRTQNATVQAHTALPVVPYSEVMDGVIEDDDQWFRVSATGTYEPEQFQLRYRSLDGAYGSEVFGVLNTSSGYVLINRGFLPRQPGFPDGEMPPAAGGEVTVTGYVRRNMRGDDNSKTPHEGQLRTIDSEFIGAAIGEDLTDGYIQLIESTPPETDVLTPLGEPSLDEGNHLSYALQWFAFTIIGVVGMGVLIRGDIRDRAKARARASAAADTHAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDG1</accession>
    <name>A0A1Q2CDG1_9ACTN</name>
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        <name evidence="3" type="ORF">SAMN05428934_101487</name>
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="SAMN05428934_101487"/>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <begin position="96"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
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            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY36580.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="655" mass="74435" checksum="36DECD396523CB40" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDG3</accession>
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        <submittedName>
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        <name evidence="2" type="ORF">RPIT_04465</name>
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        <name type="scientific">Tessaracoccus flavus</name>
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    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
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        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04465"/>
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    </dbReference>
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        <property type="protein sequence ID" value="SDY36875"/>
        <property type="gene ID" value="SAMN05428934_101499"/>
    </dbReference>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
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    </dbReference>
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    </dbReference>
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    <feature type="domain" description="SpoU_methylase" evidence="1">
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            <begin position="115"/>
            <end position="254"/>
        </location>
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            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="AQP44158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY36875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="257" mass="27656" checksum="8373EFD6A44EE556" modified="2017-04-12" version="1">MLIDVSDPSDPRLNDFVGLRDARLRQAEGRFIAEGLKIIERAFAAGCRPRALLLQPRWLDGLDELLRAWPEVPVYVGTEAMIEQVSGFHVHRGALGSFDRPGEAAWEGLLSGRRLVVCEGIVDHANTGAIARLAAGLGWDGLLVSAGGADPLYRRAIKSSMGATLSLPWRRMQSDGDLTLLKQAGFRLVASTLAPRATDLRDYRPSDRVALLLGTEGFGLSDEWLAAADDQVTIPMAAGVDSLNVATAAAILAYALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDH2</accession>
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            <fullName evidence="3">LTD domain-containing protein</fullName>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY36928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04475"/>
    <dbReference type="EnsemblBacteria" id="AQP44159">
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        <property type="gene ID" value="RPIT_04475"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY36928">
        <property type="protein sequence ID" value="SDY36928"/>
        <property type="gene ID" value="SAMN05428934_101501"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04475"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:carbohydrate metabolic process"/>
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        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
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        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001322">
        <property type="entry name" value="Lamin_tail_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036415">
        <property type="entry name" value="Lamin_tail_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00932">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74853">
        <property type="entry name" value="SSF74853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51841">
        <property type="entry name" value="LTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544431" description="LTD domain-containing protein" evidence="2">
        <location>
            <begin position="31"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="domain" description="LTD" evidence="3">
        <location>
            <begin position="25"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY36928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="1008" mass="108589" checksum="507C8BA2DBE001FD" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDR4</accession>
    <name>A0A1Q2CDR4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_04930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04930"/>
    <dbReference type="EnsemblBacteria" id="AQP44237">
        <property type="protein sequence ID" value="AQP44237"/>
        <property type="gene ID" value="RPIT_04930"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04930"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="77" mass="8359" checksum="9BAF4100A74F0A45" modified="2017-04-12" version="1">MTVQIAIRLPDDVVAFLDTSVTVGNAPSRVALVACAVERDMRRQVAEHDAAILRERGTADELDELGSWSVAHPTTED</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDR5</accession>
    <name>A0A1Q2CDR5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplU</name>
        <name evidence="6" type="ORF">RPIT_04665</name>
        <name evidence="7" type="ORF">SAMN05428934_101540</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">This protein binds to 23S rRNA in the presence of protein L20.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Contacts protein L20.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04665"/>
    <dbReference type="EnsemblBacteria" id="AQP44195">
        <property type="protein sequence ID" value="AQP44195"/>
        <property type="gene ID" value="RPIT_04665"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37846">
        <property type="protein sequence ID" value="SDY37846"/>
        <property type="gene ID" value="SAMN05428934_101540"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04665"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01363">
        <property type="entry name" value="Ribosomal_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="L21-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="L21p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001787">
        <property type="entry name" value="Ribosomal_L21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018258">
        <property type="entry name" value="Ribosomal_L21_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="PTHR21349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="SSF141091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00061">
        <property type="entry name" value="L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01169">
        <property type="entry name" value="RIBOSOMAL_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY37846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="102" mass="11233" checksum="0E216020E21B2BCE" modified="2017-04-12" version="1">MYAIVRNGGRQHKVAVGDVLDIDLVSEEVGGTVSLQPLLLVDGDEITSDAKGLDKVSVTAEVLGEKKGPKIRILKYKNKTGYKKRQGHRQRYTQVKVTDIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE16</accession>
    <name>A0A1Q2CE16_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Zinc-ribbon domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05730</name>
        <name evidence="4" type="ORF">SAMN05428934_10393</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05730"/>
    <dbReference type="EnsemblBacteria" id="AQP44372">
        <property type="protein sequence ID" value="AQP44372"/>
        <property type="gene ID" value="RPIT_05730"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67491">
        <property type="protein sequence ID" value="SDY67491"/>
        <property type="gene ID" value="SAMN05428934_10393"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05730"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026870">
        <property type="entry name" value="Zinc_ribbon_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13240">
        <property type="entry name" value="zinc_ribbon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="84"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY67491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="162" mass="17439" checksum="71A0CEAB6EB4818E" modified="2017-04-12" version="1">MKCRKCGTDSPAEARFCSACGSPLTDPTGDTTTMIPVATEERGSVELTDQEREAAKALAEGNALLVVNRGTGDSSRFLIDSDITTVGRHPESDIFLDDITVSRNHAKFVRSGGKLYLEDLGSLNGTYVNRTLLDGRTVLREGDEIQIGKYRATISLSEPGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE20</accession>
    <name>A0A1Q2CE20_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DEDD_Tnp_IS110 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44295">
        <property type="protein sequence ID" value="AQP44295"/>
        <property type="gene ID" value="RPIT_05265"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05265"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="1">
        <location>
            <begin position="20"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="363" mass="39313" checksum="35EF5F5649A516A9" modified="2017-04-12" version="1">MYKTSHTRGHRNPPSGSVVVGIDTHLDIHHAALVDAATGAPVADQQFPATPAGYLELLDWAVGHGRVSRAGVEQTGTYGAGLSAVLHAAGIEVIEINHTERGDRARHGKTDELDAYRAATAAAAGTQKGLAKHYHPAIAALRPLMVLRAHHRSSRQRAWGRVGGMLVTCPDDLADQVRGLNSAQKLARIAAWRPDLTRLHDPVNSYKLALRDLARACLDHDRAIVEIDAQLLRILTPIAPTLLAQHHVGPVTTAQLLITAGHPGRITSGDAFAKLVGVAPLPVQSGKSSRWRLSRSGDRQANSVIHRVVIGRLGTDPRSKTYIQRRVSEGKTRSEAIRALKRHVTRDLWTALQTDLNNLPHTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE74</accession>
    <name>A0A1Q2CE74_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_05905</name>
        <name evidence="2" type="ORF">SAMN05428934_103129</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44406">
        <property type="protein sequence ID" value="AQP44406"/>
        <property type="gene ID" value="RPIT_05905"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68442">
        <property type="protein sequence ID" value="SDY68442"/>
        <property type="gene ID" value="SAMN05428934_103129"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05905"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY68442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="205" mass="22273" checksum="607B098E0FA66EBA" modified="2017-04-12" version="1">MHNHFDDQAATWDEDQSKIERARTIADAIVESLRLNGDERVLEYGAGTGLVAQALGEGVGALTLADSSAGMRAAMTTKVERGTLPAATRVWDLDLSTDEVPAGEAFDLIASSLVLHHIGELDRVLEGFWSLLRSGGSVAIADLDREDGSFHEHLHDFDGHNGFDRDDLRSRLEAAGFVDVRFDDCGEVHKAGRSFGLFLATARRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE75</accession>
    <name>A0A1Q2CE75_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_05615</name>
        <name evidence="2" type="ORF">SAMN05428934_10370</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY66954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05615"/>
    <dbReference type="EnsemblBacteria" id="AQP44355">
        <property type="protein sequence ID" value="AQP44355"/>
        <property type="gene ID" value="RPIT_05615"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY66954">
        <property type="protein sequence ID" value="SDY66954"/>
        <property type="gene ID" value="SAMN05428934_10370"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05615"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY66954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="128" mass="14144" checksum="5AA231AD8D744423" modified="2017-04-12" version="1">MFDDDVIRVYVPPGWPGVVRPPGSEGWLRSAESFLLDCCPAEYRGYQVLRRHPVVLARLAREFVASQLVATRSGLMGLRAALSGVVDSATVDQAALVLQQEEARLVRVARGVDLVEQALRDVRFTPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEB5</accession>
    <name>A0A1Q2CEB5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartate--tRNA(Asp/Asn) ligase</fullName>
            <ecNumber evidence="7">6.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Aspartyl-tRNA synthetase</fullName>
            <shortName evidence="7">AspRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Non-discriminating aspartyl-tRNA synthetase</fullName>
            <shortName evidence="7">ND-AspRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">aspS</name>
        <name evidence="10" type="ORF">RPIT_06260</name>
        <name evidence="11" type="ORF">SAMN05428934_103197</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-aspartate + tRNA(Asx) = AMP + diphosphate + L-aspartyl-tRNA(Asx)</text>
            <dbReference type="Rhea" id="RHEA:18349"/>
            <dbReference type="Rhea" id="RHEA-COMP:9710"/>
            <dbReference type="Rhea" id="RHEA-COMP:9711"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.23"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.23" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06260"/>
    <dbReference type="EnsemblBacteria" id="AQP44464">
        <property type="protein sequence ID" value="AQP44464"/>
        <property type="gene ID" value="RPIT_06260"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70177">
        <property type="protein sequence ID" value="SDY70177"/>
        <property type="gene ID" value="SAMN05428934_103197"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06260"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050560">
        <property type="term" value="F:aspartate-tRNA(Asn) ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00044">
        <property type="entry name" value="Asp_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004524">
        <property type="entry name" value="Asp-tRNA-ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004115">
        <property type="entry name" value="GAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029351">
        <property type="entry name" value="GAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF5">
        <property type="entry name" value="PTHR22594:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02938">
        <property type="entry name" value="GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55261">
        <property type="entry name" value="SSF55261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00459">
        <property type="entry name" value="aspS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="9">
        <location>
            <begin position="140"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Aspartate" evidence="7">
        <location>
            <begin position="197"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="562"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="582"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="219"/>
            <end position="221"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="451"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="485"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="492"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="537"/>
            <end position="540"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for tRNA non-discrimination" evidence="7">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <feature type="site" description="Important for tRNA non-discrimination" evidence="7">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY70177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="597" mass="65433" checksum="F601D29A920A8612" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CED3</accession>
    <name>A0A1Q2CED3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06270</name>
        <name evidence="3" type="ORF">SAMN05428934_103199</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44466">
        <property type="protein sequence ID" value="AQP44466"/>
        <property type="gene ID" value="RPIT_06270"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70226">
        <property type="protein sequence ID" value="SDY70226"/>
        <property type="gene ID" value="SAMN05428934_103199"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06270"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY70226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="298" mass="32312" checksum="4CCC8426713B9DAE" modified="2017-04-12" version="1">MIHADVPTRRNSLSVAIRRSERTITKVLATTTTGSLMMLVAAFGLSDHLAMPHVGNAIVWLAVAGLVGVIVFGVPFLVAKGVRTASFAAAAARSRPELQLWASAQGFRFLPKVDGIFGDDTLPVNGLLAALIAHDAELGLELWRDSSPHGKRFDDVVLGRLEGAGDVVVATASGLPAPVLRSRFVALRSGHRLPALSVTDRHNDELWVRPGQQFESVHFNERWRVIAKDPRYASQMVHASLMELFVQSSPDIHRVDFADGWVISWADADVSAAELNGHLQLLSTAAAQVPRFVLRDNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEF9</accession>
    <name>A0A1Q2CEF9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Spermidine/putrescine import ATP-binding protein PotA</fullName>
            <ecNumber evidence="8">7.6.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">potA</name>
        <name evidence="10" type="ORF">RPIT_06405</name>
        <name evidence="11" type="ORF">SAMN05428934_103226</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.11" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06405"/>
    <dbReference type="EnsemblBacteria" id="AQP44488">
        <property type="protein sequence ID" value="AQP44488"/>
        <property type="gene ID" value="RPIT_06405"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70950">
        <property type="protein sequence ID" value="SDY70950"/>
        <property type="gene ID" value="SAMN05428934_103226"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06405"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015417">
        <property type="term" value="F:ABC-type polyamine transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005893">
        <property type="entry name" value="Sp_pt_ABC_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01187">
        <property type="entry name" value="potA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="22"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="58"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY70950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="383" mass="41912" checksum="EECD481D805A926D" modified="2017-04-12" version="1">MTDLAAADKLLEGTPTDTVGRLQLRGLTKEFGNGPEKVTAVDAIDLDIEPGEFITLLGPSGCGKTTTLRMIAGFEDPSGGEVVLDGRNMIDIPPNKRPMAMVFQSYALFPHLKVRDNVGYGLKLRRLPATQLNEEVDLALESMNLQQYANRAPNQLSGGQQQRVALARAMVMKPKVLLFDEPLSNLDAKLREQMRLEIRRLQRHLGITSVYVTHDQSEAMSMSDRIVVMNKGQVEQAAPPETIYRHPASVFVADFIGRANFLDVRVISHDGDGRATVEVLGQRVQVPAHPDAASAKDVVLLVRPESLRLVSVGSHGAGDLDGHEGRVVTSVFFGDTVEYEVETEHGKMAAVVADPNVADIHPEGADVEVRFNAERAWLLPRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEG1</accession>
    <name>A0A1Q2CEG1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B</fullName>
            <shortName evidence="11">Asp/Glu-ADT subunit B</shortName>
            <ecNumber evidence="11">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">gatB</name>
        <name evidence="13" type="ORF">RPIT_06505</name>
        <name evidence="14" type="ORF">SAMN05428934_103246</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14513"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="Rhea" id="RHEA-COMP:9677"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 11">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4 11">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the GatB/GatE family. GatB subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06505"/>
    <dbReference type="EnsemblBacteria" id="AQP44504">
        <property type="protein sequence ID" value="AQP44504"/>
        <property type="gene ID" value="RPIT_06505"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71502">
        <property type="protein sequence ID" value="SDY71502"/>
        <property type="gene ID" value="SAMN05428934_103246"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06505"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00121">
        <property type="entry name" value="GatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004413">
        <property type="entry name" value="Apn/Gln-ADT_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017959">
        <property type="entry name" value="Asn/Gln-tRNA_amidoTrfase_suB/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006075">
        <property type="entry name" value="Asn/Gln-tRNA_Trfase_suB/E_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018027">
        <property type="entry name" value="Asn/Gln_amidotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017958">
        <property type="entry name" value="Gln-tRNA_amidoTrfase_suB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659">
        <property type="entry name" value="PTHR11659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02934">
        <property type="entry name" value="GatB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02637">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00845">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="SSF89095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00133">
        <property type="entry name" value="gatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01234">
        <property type="entry name" value="GATB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GatB_Yqey" evidence="12">
        <location>
            <begin position="347"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP44504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY71502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="495" mass="53308" checksum="AB35DF22C013CF97" modified="2017-04-12" version="1">MTELVDYDELLTRYDPALGLEVHVELNTATKMFCGCPNVFGGDPNTHVCPVCLGLPGSLPVINGKAVESAIRIGLALNCEIAQWCRMARKNYFYPDMTKNFQTSQYDEPIAYDGFVELEVDGETFRVEIERAHMEEDAGKATHVGTSGRIHGADYSLIDYNRAGVPLIEIVTRPILGAGAKAPAVAKAYVAHLRELVKSLGVSDARMEQGSLRCDANISLMPAGSDVLGTRTETKNVNSLRSVERAIRYEMTRQAAILDGGGRVIQETRHFDESTGTTGSGRSKEQAEDYRYFAEPDLMPIAPSAEWVEALRETLPEPPAEHRRRLQGEWGFSDIDFHSIVASGALALVEETVAAGTTPAAARKWWVTELARRANQDGLELDELAITPAQVAAVQGLVDDGQVNDKLARQVIEGVLAGEGEPADVVKSRGLAVVSDEGALSSAVDEVIAANPDVADKIRAGKVAAAGALIGQVMKAMRGQADAGKVRELILAKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEI1</accession>
    <name>A0A1Q2CEI1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_06520</name>
        <name evidence="4" type="ORF">SAMN05428934_103249</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44507">
        <property type="protein sequence ID" value="AQP44507"/>
        <property type="gene ID" value="RPIT_06520"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71584">
        <property type="protein sequence ID" value="SDY71584"/>
        <property type="gene ID" value="SAMN05428934_103249"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06520"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY71584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="67" mass="7482" checksum="A61E5CFE765600D4" modified="2017-04-12" version="1">MRIFSNLNLDGPSPLRAQPGRGEWGAQGIPSTRWKKFQRVIIPILVVAIAVGLFFLGRVFYLILTGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CER5</accession>
    <name>A0A1Q2CER5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-dependent RNA helicase HrpA</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">ATP-dependent helicase HrpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_06970</name>
        <name evidence="5" type="ORF">SAMN05428934_11051</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06970"/>
    <dbReference type="EnsemblBacteria" id="AQP44587">
        <property type="protein sequence ID" value="AQP44587"/>
        <property type="gene ID" value="RPIT_06970"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09092">
        <property type="protein sequence ID" value="SDZ09092"/>
        <property type="gene ID" value="SAMN05428934_11051"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06970"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024590">
        <property type="entry name" value="HrpA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010222">
        <property type="entry name" value="RNA_helicase_HrpA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11898">
        <property type="entry name" value="DUF3418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01967">
        <property type="entry name" value="DEAH_box_HrpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
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            <end position="177"/>
        </location>
    </feature>
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        <location>
            <begin position="203"/>
            <end position="366"/>
        </location>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="484"/>
            <end position="500"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ09092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="1258" mass="138608" checksum="AC6AD8C395F80E95" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">RP1T</strain>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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            <end position="232"/>
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    <evidence type="ECO:0000259" key="1">
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            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="AQP44621.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
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    </evidence>
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            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="247" mass="27716" checksum="CE5047E7FB6E39A1" modified="2017-04-12" version="1">MTTYSRTKEFEGATFVRTSFKGAAIWFSDVSGVKMRSVDVDGLDIDSHDLFFGSLVVNGVDVVPLVDAELNRLFPGRELQKAETPEGLREGWAAVQAAWRETVEATPETMVDAHVEDEWSLAETLRHLILATDAWLGGAILGVDQPFHEIGQVFTGAKEMGFDMSIFRKEPPRFEEVLEVRAERQRMVTDFLATATPELLAEKRDDPWGGDWHPTVGDCIRVILEEEWAHLRYTRRDLALLSAPSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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                <person name="Schumann P."/>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">RP1</strain>
        </source>
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        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
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        </source>
    </reference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="445" mass="48589" checksum="108BC84240E6CF6F" modified="2017-04-12" version="1">MSNPTPSGPFDFEALKKMLEQLGLGNADEIGFEQLVAQIQKMQAAGGGFTFGMTNADRDPDAAWRTTLTAAKQIVSASGADPELRVEEKAAIVDAERLAQSWLTPHTSFAETGRPARAVTKAAWLDATSDGWRAVIEPIIDGLTEALQRNTSVEGGDEFAAMQQMLAPMMRTSASLIYRDRLKKELAEVAGDILTGTELGFNLLGVPDVLVLPANVAQFTRDLDASDRDVTLYLLLREAARQRLFHAVGWLSPQLSALLGHFAREIEIDFDAIASQLQPENLESLSIEQVVAVGESVRGSFFQPASTPTQVEILDRLEVLLALVEGWVDHVVGRATASWMPNAPQLEEVIHRRRASNTPVNGVFAELLGLDLHPRLVRDAKNLWAAVEHHRGMDGRDAIWGHPDLLPTADHLADPLSFAAGEPVRELAEDPLDAELRKLLGERDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEW5</accession>
    <name>A0A1Q2CEW5_9ACTN</name>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 6">RP1</strain>
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    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="3">RP1T</strain>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="1610493.RPIT_07300"/>
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <location>
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        </location>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ18081.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="103" mass="11227" checksum="FF21D1A06383AFC9" modified="2017-04-12" version="1">MTTMTQATYGVRGLSCWRCMISAVEAVRALPGVHTVGMDLEPHGESLLTLAPAGAVTSAQVRATLDRSGFELTRRRRRPRPSRLRHALTTAPVDDGREILTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF28</accession>
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        <name evidence="2" type="ORF">SAMN05428934_1252</name>
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        <lineage>
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    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44680.1"/>
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    </dbReference>
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        <property type="protein sequence ID" value="SDZ23506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44680">
        <property type="protein sequence ID" value="AQP44680"/>
        <property type="gene ID" value="RPIT_07565"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ23506">
        <property type="protein sequence ID" value="SDZ23506"/>
        <property type="gene ID" value="SAMN05428934_1252"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07565"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ23506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="449" mass="48159" checksum="9D3A55713ABF8D8B" modified="2017-04-12" version="1">MASAPTGETSAPASSPRLGRALFFVHQQARVINDPVVRAKLSQLTAAGEAMGYAVTLKDHGRLSGTMAMEFAVQAGIGEQRLLNEVLPKLKEADLIDYTLDLTTGGVATIEEFVGLSGRIIDQAMKVTERYSPSQVEIAVLHSTELASWAPLTLGQHAEQLHKRGFEDKVIEEAIRLSLAAGVNLRVKSADLGEYVIYNPHVWAAHHLPIAGFLKGLPPAERDSLLGLCEQASSSPGLALRAYDTFQPGMLSSARKVGLVQAATVKSSVANGQQTYVFSPMLESEDDKLQTTEVLHQRKLFVAHILYGHEKAIAGRGRIYDPRVLVRSLLRKGAVGPASNIASDYHLLEASGIVAVRQSTTEPGRAYLELVKKEIVEGGLGWIEASYSNGSGAGADLSALTSPSDWVSPEADRANLPDTGAAMEIAESAILRLREARKEATSAARRDVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF79</accession>
    <name>A0A1Q2CF79_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Regulatory protein, luxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_07795</name>
        <name evidence="4" type="ORF">SAMN05428934_11824</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000018">
        <property type="protein sequence ID" value="SDZ21636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07795"/>
    <dbReference type="EnsemblBacteria" id="AQP44720">
        <property type="protein sequence ID" value="AQP44720"/>
        <property type="gene ID" value="RPIT_07795"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ21636">
        <property type="protein sequence ID" value="SDZ21636"/>
        <property type="gene ID" value="SAMN05428934_11824"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07795"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="81"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ21636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="142" mass="16218" checksum="AD5856923A36EDA8" modified="2017-04-12" version="1">MSTAYSIRTDRLILRPLHEADVDVVVAYRNHPDVSTLQDWELPVTRDRVERQVAETWMDLEAQGDVLVFSGILEQLDQRPAPARPNRLTAREHEVLELLREGLPDKQIATRLQISVKTVEKHVGSVLRKNGVHSRTELLVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF97</accession>
    <name>A0A1Q2CF97_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl-CoA carboxyl transferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Acetyl-CoA carboxylase carboxyl transferase subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_08190</name>
        <name evidence="4" type="ORF">SAMN05428934_11537</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08190"/>
    <dbReference type="EnsemblBacteria" id="AQP44778">
        <property type="protein sequence ID" value="AQP44778"/>
        <property type="gene ID" value="RPIT_08190"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19775">
        <property type="protein sequence ID" value="SDZ19775"/>
        <property type="gene ID" value="SAMN05428934_11537"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08190"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000438">
        <property type="entry name" value="Acetyl_CoA_COase_Trfase_b_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01070">
        <property type="entry name" value="ACCCTRFRASEB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="2">
        <location>
            <begin position="232"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ19775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="519" mass="55612" checksum="E157F105D3FD4238" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFI4</accession>
    <name>A0A1Q2CFI4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Predicted oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08335</name>
        <name evidence="3" type="ORF">SAMN05428934_1158</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08335"/>
    <dbReference type="EnsemblBacteria" id="AQP44805">
        <property type="protein sequence ID" value="AQP44805"/>
        <property type="gene ID" value="RPIT_08335"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19173">
        <property type="protein sequence ID" value="SDZ19173"/>
        <property type="gene ID" value="SAMN05428934_1158"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08335"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ19173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="320" mass="34218" checksum="C7D1EA99D078DA4E" modified="2017-04-12" version="1">MQLRPLGASGLQVSRLGLGTMAWGRDVDWPTARELLTEFVEAGGNFVDTAPAYGAGVAERMLGKALAAGLPRETLVIASKAGFVVRDGRRVIDTSRGALLTDLEGTLRRLKTDHLDLWQVHAWGDAPMDETLSALDSAVQRGLVRYVGVSNFVGWQTATAATWQAADRARTTLSSVQVEYSLLARRAEVEVMGAARHHNLGVLAWSSLGRGALTGKYRGGRVPRDSRAASEHFSWFVEPYLQPRSAAIVDAVAHAAQGLGLTPTQVALLWVRDAPQVASALVGPRTVDQLAELLDAEQKELVAPIVSALDDISGGANALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFN2</accession>
    <name>A0A1Q2CFN2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09030</name>
        <name evidence="3" type="ORF">SAMN05428934_107119</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09030"/>
    <dbReference type="EnsemblBacteria" id="AQP44918">
        <property type="protein sequence ID" value="AQP44918"/>
        <property type="gene ID" value="RPIT_09030"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98627">
        <property type="protein sequence ID" value="SDY98627"/>
        <property type="gene ID" value="SAMN05428934_107119"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09030"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005662">
        <property type="entry name" value="GTP-bd_Era"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698">
        <property type="entry name" value="PTHR42698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="454"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY98627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="571" mass="61386" checksum="EDBC5FA4800B9BA9" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFN7</accession>
    <name>A0A1Q2CFN7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09110"/>
    <dbReference type="EnsemblBacteria" id="AQP44929">
        <property type="protein sequence ID" value="AQP44929"/>
        <property type="gene ID" value="RPIT_09110"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09110"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003933">
        <property type="term" value="F:GTP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003801">
        <property type="entry name" value="GTP_cyclohydrolase_FolE2/MptA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36445">
        <property type="entry name" value="PTHR36445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02649">
        <property type="entry name" value="GCHY-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="319" mass="34237" checksum="F75F5AFA5A41C85F" modified="2017-04-12" version="1">MAVHDVTDSSVDRARAALVKAGFPGFTYVLDPLSQDSRTDVPTFEPDVLIAAQAGITGVRLPLRIDDGWPVLSADVDLTIGLNANQRGAHMSRLQEAIVEVGSQSHQSVPATAERLAALTSATQPGPVFVTLRVDQQPAILSAITRRPSSVDVSTVVTLEYSGRGTTRCEVSLTVQVMTACPCTIAYSKLSSERRSGVTYAPDMPPTFTHSQPGTLTVGIEATTIDAATSAELLSAVRSCAVLRESVLKRPDEHELVDRAHRRPQFTEDLARFAAAEVATRVTSETTVFARAILNESIHPHRAAAQVRARAGELQRSFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFQ5</accession>
    <name>A0A1Q2CFQ5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_09100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44927">
        <property type="protein sequence ID" value="AQP44927"/>
        <property type="gene ID" value="RPIT_09100"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09100"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="153" mass="17020" checksum="307DB7AC733014FE" modified="2017-04-12" version="1">MGDIWWGVHNATHLDQIKHVADAGRNPNEIEYGEGLLAAESLAMTVEMLAGLEGRGTPAARVVWEGLAERLARMPIPSELSSPTVVQARQLADPEFGALPTLASAYTTGAIRLLESRFEHELIPPTLRESMLVRWRRLVDAEPWLRREIGSMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFS6</accession>
    <name>A0A1Q2CFS6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Adenine-specific DNA-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_09340</name>
        <name evidence="6" type="ORF">SAMN05428934_102441</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY60870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09340"/>
    <dbReference type="EnsemblBacteria" id="AQP44964">
        <property type="protein sequence ID" value="AQP44964"/>
        <property type="gene ID" value="RPIT_09340"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY60870">
        <property type="protein sequence ID" value="SDY60870"/>
        <property type="gene ID" value="SAMN05428934_102441"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09340"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006306">
        <property type="term" value="P:DNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002295">
        <property type="entry name" value="N4/N6-MTase_EcoPI_Mod-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00506">
        <property type="entry name" value="D21N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="4">
        <location>
            <begin position="92"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY60870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="598" mass="66304" checksum="59AF339036081842" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFW4</accession>
    <name>A0A1Q2CFW4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09160</name>
        <name evidence="3" type="ORF">SAMN05428934_107145</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY99139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44935">
        <property type="protein sequence ID" value="AQP44935"/>
        <property type="gene ID" value="RPIT_09160"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY99139">
        <property type="protein sequence ID" value="SDY99139"/>
        <property type="gene ID" value="SAMN05428934_107145"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09160"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY99139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="105" mass="11860" checksum="AFD332E6632603EF" modified="2017-04-12" version="1">MNDDEELRWVRRREGTHRSESRATRGYERDLLRDDDTRNLLGPTESRPADIDEIVRSRGPVGPARPSPGQEFRYQVGDAIMEALAPYIERGVDVAVDAAVLGVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG27</accession>
    <name>A0A1Q2CG27_9ACTN</name>
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        <submittedName>
            <fullName evidence="9">Phage shock protein C (PspC) family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_09905</name>
        <name evidence="9" type="ORF">SAMN05428934_102325</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY57593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09905"/>
    <dbReference type="EnsemblBacteria" id="AQP45063">
        <property type="protein sequence ID" value="AQP45063"/>
        <property type="gene ID" value="RPIT_09905"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57593">
        <property type="protein sequence ID" value="SDY57593"/>
        <property type="gene ID" value="SAMN05428934_102325"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09905"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007168">
        <property type="entry name" value="Phageshock_PspC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04024">
        <property type="entry name" value="PspC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="PspC" evidence="7">
        <location>
            <begin position="17"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY57593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="417" mass="44411" checksum="1B9CA8D2707C3A2F" modified="2017-04-12" version="1">MTDQRDLLRAPPRAPLGRRVEGRMIAGVAVGLSEHLDLSVRVVRFGFVLLSFLSGMGVVAYLALWVFMPRANTVESAAGLDAAARRGMRPASSTATQRADTGILVSGGMIAVGILWAFVVAGAVPSNLFWPAVLGGAGVIVIWLQVDERVPHAADQVAVGPWGRFTRGGGAMSVLRLMGGLLLVLAGVTWILATRVGLAQLPGILGASALLLAGLVVVAAPWLYQQRGRIRRAEAERLRAEARSDMAAHLHDSVLQTLALIQRQAGDAATVSALARKQERELRTWLYGETPRDESLRAALAAIASDVESNFPINVEVVCVGDAQVDDRVQALVQAVREAVINAAKHSQSPRVDVYAEVLGTGIEAFVRDRGVGFDPARVPEGRMGVRESIKARLERQGGTAVIRSEAGTGTEVRLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG29</accession>
    <name>A0A1Q2CG29_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PspC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_09910</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09910"/>
    <dbReference type="EnsemblBacteria" id="AQP45064">
        <property type="protein sequence ID" value="AQP45064"/>
        <property type="gene ID" value="RPIT_09910"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09910"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007168">
        <property type="entry name" value="Phageshock_PspC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04024">
        <property type="entry name" value="PspC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="PspC" evidence="7">
        <location>
            <begin position="22"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="372" mass="38594" checksum="AC5378840DAFF5B7" modified="2017-04-12" version="1">MARNDLDLAWLDPSLGALQRRQPGVFTGLAQAIADRLGVDPVLVRVAFVVLALCGGLGVALYGWGSALTAGPDTRRPIDAYLPSFRGWPSPWAKAVVVTTTLAVMALTGAITPLPWLSGVALLGAFVIIRRTQTDTQQPSLTGHDAREIQNTPRDDHELIASWRASMAAAAGDARPLPTVELYGAPPLPEPRVSSTVAPPRTSWGAGIATVIVMVAVAPAAYLIFGLSPLETLAASSASAGVVVAGVGMLTRRRVPRSVLSLVVVLAISSALMAVQTAAPVPAAADGVLNIRVVGERSELVLTADDLEGITTIDLDAVGSDVTVRLPGTIENLTVDRGFGVVTHSSGAPDDALEVAVVVDLIAARVHFEEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG70</accession>
    <name>A0A1Q2CG70_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Xaa-Pro aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_10100</name>
        <name evidence="8" type="ORF">SAMN05428934_102285</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase M24B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10100"/>
    <dbReference type="EnsemblBacteria" id="AQP45097">
        <property type="protein sequence ID" value="AQP45097"/>
        <property type="gene ID" value="RPIT_10100"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56554">
        <property type="protein sequence ID" value="SDY56554"/>
        <property type="gene ID" value="SAMN05428934_102285"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10100"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP_N" evidence="6">
        <location>
            <begin position="38"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY56554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="479" mass="53084" checksum="FF805F46B1108A3A" modified="2017-04-12" version="1">MTESPDASSNRRDPYSEAFKKFIVADWAPYSDDLPERLPAADHTPARREKLAAEFPGKTLVIPAGPLKVRSNDTDYRFRPHTAFAYYTGLGEDREPDAVLVIRDEQSTLFFRPRAPRTDREFYADPRYGEVWVGQRDSLEELQSAVGFECRAISELPSVLSEAGQSLLVIREADPSVTAIVDEARGDQTTALDGDLERCVSEARFIKDDFEVAEMRRACDATRTGFEAVARELPNAVANGRGERWVEGIFGLHARHLGNAVGYDTISAGGDHANTLHWIRNDGDLRDGDLLLLDAGVEVNSLYTADITRTMPVGGTFSEPQRRVYDAVLAAQTAGIEACRDGNLFADVHRAAITVLAHFFEELGILPCTAEESLAEEGGFHRRWMVHGTSHHLGLDVHDCARAKMENYRLGTLHSGMIITVEPGIYFKSTDLLVPEEYRGIGIRIEDDILITDGDPVNLSEALPREAEAVEAWLADLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG97</accession>
    <name>A0A1Q2CG97_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10305</name>
        <name evidence="3" type="ORF">SAMN05428934_102244</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45136">
        <property type="protein sequence ID" value="AQP45136"/>
        <property type="gene ID" value="RPIT_10305"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55416">
        <property type="protein sequence ID" value="SDY55416"/>
        <property type="gene ID" value="SAMN05428934_102244"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10305"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035172">
        <property type="entry name" value="DUF5302"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17227">
        <property type="entry name" value="DUF5302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY55416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="60" mass="6475" checksum="3EFFC8DBDC752BD4" modified="2017-04-12" version="1">MSEDQEAVPLDPKEAMRQALERKKQGQGQHGPGGPEADRALGHAHGQMGGKRQFRRKAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGD8</accession>
    <name>A0A1Q2CGD8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">4-hydroxy-3-methylbut-2-enyl diphosphate reductase</fullName>
            <shortName evidence="5">HMBPP reductase</shortName>
            <ecNumber evidence="5">1.17.7.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ispH</name>
        <name evidence="6" type="ORF">RPIT_10510</name>
        <name evidence="7" type="ORF">SAMN05428934_102203</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24488"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="EC" id="1.17.7.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24825"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the IspH family.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.4" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY54226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10510"/>
    <dbReference type="EnsemblBacteria" id="AQP45174">
        <property type="protein sequence ID" value="AQP45174"/>
        <property type="gene ID" value="RPIT_10510"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY54226">
        <property type="protein sequence ID" value="SDY54226"/>
        <property type="gene ID" value="SAMN05428934_102203"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10510"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00097"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00059">
        <property type="reaction ID" value="UER00105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051745">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050992">
        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13944">
        <property type="entry name" value="lytB_ispH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00191">
        <property type="entry name" value="IspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003451">
        <property type="entry name" value="LytB/IspH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30426">
        <property type="entry name" value="PTHR30426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02401">
        <property type="entry name" value="LYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00216">
        <property type="entry name" value="ispH_lytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="230"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY54226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="324" mass="35092" checksum="15231BC1843B0ADE" modified="2017-04-12" version="1">MSVSELNKRVVLAAPRGYCAGVDRAVITVEKALDLYGAPVYVRKQIVHNKHVVETLEDRGAIFVEELDEVPPGSTVVFSAHGVSPAVHAEAAERGLKTIDATCPLVTKVHHEAKRFAADGKQILLIGHAGHEEVEGTMGEAPDNTLLVQSPDDVDNIELPEGTNVAWLSQTTLSVDETMETVGRLREKFPLLMDPPSDDICYATQNRQLAVKQIASGGCDLMIVVGSSNSSNSVRLVEVALEAGAKTSYRVDNASEIDPAWLEGVQSVGVTSGASVPEELVDGVLQYLRDRGYPVAIEERLTEETLQFALPPELRKDIRRAVKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGF1</accession>
    <name>A0A1Q2CGF1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10600</name>
        <name evidence="3" type="ORF">SAMN05428934_102185</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY53649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10600"/>
    <dbReference type="EnsemblBacteria" id="AQP45191">
        <property type="protein sequence ID" value="AQP45191"/>
        <property type="gene ID" value="RPIT_10600"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY53649">
        <property type="protein sequence ID" value="SDY53649"/>
        <property type="gene ID" value="SAMN05428934_102185"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10600"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY53649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="234" mass="26150" checksum="7E35005FB9822310" modified="2017-04-12" version="1">MEMSPKPGSHAQLGRTFIAQQRVISVLSFFLPLFLITWSVLSGEGLRGSLSEYYYTPVRDIFVGVLCALSLFFWSYRGYHPHKAELRADRVVAKIASVSAALVALAPLKPRQVGECTLLQCVFGEQATDWVHNVAAVIFMTSLATFCLVLFPMTAIQRPDLGRRLVIYGICGTVIVAAMLLMVLWKFLPVDVYFALGHYKPIFMLETMALFAFSIAWLLRSRAVEDAALAQYDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGJ5</accession>
    <name>A0A1Q2CGJ5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_10795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10795"/>
    <dbReference type="EnsemblBacteria" id="AQP45223">
        <property type="protein sequence ID" value="AQP45223"/>
        <property type="gene ID" value="RPIT_10795"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10795"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013292514" evidence="2">
        <location>
            <begin position="24"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="238" mass="24843" checksum="7ED00669F475982D" modified="2017-04-12" version="1">MYRAGVAATAAVLLLVGCSGGSAPTPSPPMSPGTTPPDVVSSEPVPTSTSASAQPSAPPTFSDSATPPSAPTTASPTSSSTDSPPGDLDQLHPWVTARSEEEPRQAAGDWQEIIGVRTGAHEGYDRVVLDLSGDDPLLGWFAGFADEAIEDPTGFPLEIDGGAFLELGIWAIDWTTDRPERFSGPVDVDGLDNVTAVAFGGLFEAQQQILIGLEERTAYRVFTLSDPARIVVDIKHAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGK6</accession>
    <name>A0A1Q2CGK6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glyco_hyd_65N_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_10970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10970"/>
    <dbReference type="EnsemblBacteria" id="AQP45252">
        <property type="protein sequence ID" value="AQP45252"/>
        <property type="gene ID" value="RPIT_10970"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10970"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027414">
        <property type="entry name" value="GH95_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14498">
        <property type="entry name" value="Glyco_hyd_65N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012388233" description="Glyco_hyd_65N_2 domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hyd_65N_2" evidence="2">
        <location>
            <begin position="37"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="236" mass="25066" checksum="F2E2EACC7841220A" modified="2017-04-12" version="1">MVAGLSAALIASTAVVTGLMAPQAAAAPQTEQDALVLRYTAPAPLNRWQEQALPIGNGALGASIFGQVTNDEVFLNEKTLWTGGPGVDGYRYGNYPESEIEQRRANLEQVRDTINENGSMTAGAVANLLGQPKLGYGSYQSFGRLQFAFDNGAGTATGYERSLDIDNSIAKVTYTVGQTTFTREYFASYPDNVIVSGALRPMPGSARGAAGGQIRTPPMWVVGRLRSLRVAAQEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGL9</accession>
    <name>A0A1Q2CGL9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">5-formyltetrahydrofolate cyclo-ligase</fullName>
            <ecNumber evidence="3">6.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_11030</name>
        <name evidence="5" type="ORF">SAMN05428934_10297</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP = 5,10-methenyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10488"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.2" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY50933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11030"/>
    <dbReference type="EnsemblBacteria" id="AQP45261">
        <property type="protein sequence ID" value="AQP45261"/>
        <property type="gene ID" value="RPIT_11030"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY50933">
        <property type="protein sequence ID" value="SDY50933"/>
        <property type="gene ID" value="SAMN05428934_10297"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11030"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030272">
        <property type="term" value="F:5-formyltetrahydrofolate cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002698">
        <property type="entry name" value="FTHF_cligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407:SF1">
        <property type="entry name" value="PTHR23407:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01812">
        <property type="entry name" value="5-FTHF_cyc-lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006806">
        <property type="entry name" value="FTHF_cligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02727">
        <property type="entry name" value="MTHFS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="7"/>
            <end position="11"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="134"/>
            <end position="142"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006806-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY50933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="191" mass="20428" checksum="871D6D0D82CBEBEE" modified="2017-04-12" version="1">MPSDAQKDSLRSRVSAARSRVTDGEWSAVSRAMTRSALNFADARPTATVALYASRAAEPETGELITELARRGWRVLLPVIRRAVDWAEFGGWDEMAVGWGGIPQPTGPRLGAPALASASLIFVPCTAIGRDFSRLGTGGGWYDRALLHRTADAAVIALVREADVFDTVPTEPHDVAVDGYITEAGATFKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGM1</accession>
    <name>A0A1Q2CGM1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hemerythrin</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Hemerythrin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11070</name>
        <name evidence="3" type="ORF">SAMN05428934_10290</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY50703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45268">
        <property type="protein sequence ID" value="AQP45268"/>
        <property type="gene ID" value="RPIT_11070"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY50703">
        <property type="protein sequence ID" value="SDY50703"/>
        <property type="gene ID" value="SAMN05428934_10290"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11070"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin" evidence="1">
        <location>
            <begin position="13"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY50703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="152" mass="16475" checksum="D27173B2E5793287" modified="2017-04-12" version="1">MCSYCGCDSITVIGRFMEEHVEIINACGDLRHAVADGGDVPGAAAALGALLGPHTASEEVGLFAVMKRRDEFTDHVSTLCGEHRSLDELLAAIADGEHELMESFEKALRDHIHKEDNGLFPAAAMGLDGEEWIEIDQVTHDHDHATGTVHHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGN2</accession>
    <name>A0A1Q2CGN2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_11130</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11130"/>
    <dbReference type="EnsemblBacteria" id="AQP45279">
        <property type="protein sequence ID" value="AQP45279"/>
        <property type="gene ID" value="RPIT_11130"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11130"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012659219" evidence="3">
        <location>
            <begin position="26"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="322" mass="32876" checksum="D13B5DDE4F777892" modified="2017-04-12" version="1">MNLRTAAAALALGLGLAALSLPSLAEEIAPPEGSTPVVGMAPDPQSDGLWLAGPSADDGVILHSADGREVTFGGDPLSVQALAWSGDRLWIADIGDEPAERESVVVFRLGSVAGGRSTYHAFDFQYDDGPRDAKAMMISGRGRIYIATTGDDPGIYRAPLEPSRQDLNTLTRVTDAPDGVTDGAFLSDGATMALRTAAGIEYIDAFTWETLATDTIVGGAESESIAVGSDDTVYVGGNPSIRVVEVATSDVTTSLPPEAEAGASATPSPSPTPDATGTQAPPGEVPVEEPSDSPARTGTMIALVLAGIVAVTAGALTFLLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGQ3</accession>
    <name>A0A1Q2CGQ3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10815</name>
        <name evidence="2" type="ORF">SAMN05428934_102141</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY52260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10815"/>
    <dbReference type="EnsemblBacteria" id="AQP45225">
        <property type="protein sequence ID" value="AQP45225"/>
        <property type="gene ID" value="RPIT_10815"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY52260">
        <property type="protein sequence ID" value="SDY52260"/>
        <property type="gene ID" value="SAMN05428934_102141"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10815"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY52260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="184" mass="19416" checksum="1FB1656C62CE51B0" modified="2017-04-12" version="1">MNHGLIVAGDDPEKIRAQSHEVLERIKQAVAEARPDLTDVSEAFRSAVGGDVVATDASVVAVAFPMTEAGARFLVEGPLIPDQIVYSGSFPVVISEGDDVAAVVERHRERHGIDPIVMVAPGLGVAAVGASAKQARTAVEVYVDALTVGQAASALGSVRALDDAERRFIETWEAEAYRQQVASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGQ7</accession>
    <name>A0A1Q2CGQ7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">23S rRNA (Guanosine(2251)-2'-O)-methyltransferase RlmB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">23S rRNA (Guanosine2251-2'-O)-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_11270</name>
        <name evidence="4" type="ORF">SAMN05428934_10249</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY49551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11270"/>
    <dbReference type="EnsemblBacteria" id="AQP45302">
        <property type="protein sequence ID" value="AQP45302"/>
        <property type="gene ID" value="RPIT_11270"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY49551">
        <property type="protein sequence ID" value="SDY49551"/>
        <property type="gene ID" value="SAMN05428934_10249"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11270"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004441">
        <property type="entry name" value="rRNA_MeTrfase_TrmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46429">
        <property type="entry name" value="PTHR46429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08032">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00186">
        <property type="entry name" value="rRNA_methyl_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_sub_bind" evidence="2">
        <location>
            <begin position="73"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY49551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="317" mass="32944" checksum="7B8ED75D6AE67EDA" modified="2017-04-12" version="1">MAGNSSRRGATSKGKGKTAGSGGRIRRSLEGKGPTPKAEDRPYHKAYKAKQAAQRRTQAKPKAARKSAVGADWVVGRNPVYEALTAGLPVKQAYVAEGADRDDRLRDILRFTAEHGLPMLQVTRAELDRVTGGLVHQGVALQLPAYEYADPEDVLADALDSDGIVVALDGITDPRNLGAIIRSAAAFGATGAIIPSRRSASMTAAAWKTSAGAAARLPIAMATNLNRALEQAAKMGFTIIGLAGEGEVPISGAAGLDGPLLIVVGSEDEGLARLVREHCDQLVNIPIGSAVESLNASVAAAIALYEVNQQRTGVTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGT2</accession>
    <name>A0A1Q2CGT2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">2,3-bisphosphoglycerate-dependent phosphoglycerate mutase</fullName>
            <shortName evidence="4">BPG-dependent PGAM</shortName>
            <shortName evidence="4">PGAM</shortName>
            <shortName evidence="4">Phosphoglyceromutase</shortName>
            <shortName evidence="4">dPGM</shortName>
            <ecNumber evidence="4 5">5.4.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">gpmA</name>
        <name evidence="6" type="ORF">RPIT_11330</name>
        <name evidence="7" type="ORF">SAMN05428934_10237</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.11" evidence="4 5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY49136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11330"/>
    <dbReference type="EnsemblBacteria" id="AQP45314">
        <property type="protein sequence ID" value="AQP45314"/>
        <property type="gene ID" value="RPIT_11330"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY49136">
        <property type="protein sequence ID" value="SDY49136"/>
        <property type="gene ID" value="SAMN05428934_10237"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11330"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046538">
        <property type="term" value="F:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01039">
        <property type="entry name" value="PGAM_GpmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005952">
        <property type="entry name" value="Phosphogly_mut1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11931">
        <property type="entry name" value="PTHR11931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01258">
        <property type="entry name" value="pgm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="2 4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="9"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="22"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="88"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="115"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="184"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="4">
        <location>
            <position position="10"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="4">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY49136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="249" mass="28047" checksum="67D32717288237E7" modified="2017-04-12" version="1">MTAKLILLRHGESEWNAKNLFTGWVDVDINEKGVGEAEAAAGLLKAEGLLPDVLHTSLLRRAIHTANIALDGCDRHWIPVRRHWRLNERHYGALQGKDKAQTLEQYGEEQFMLWRRSYDTPPPPIDVDDEFSQHHDPRYADIPEADRPRTECLKDVVARLLPYWEAHIVPDLAEGKTVLVTAHGNSLRALVKHLDGISDEEIAGLNIPTGIPLYYELDEDYKPVTPGGRYLDPEAAKASIEAVKNQGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGW4</accession>
    <name>A0A1Q2CGW4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SpoU rRNA Methylase family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">rRNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11565</name>
        <name evidence="3" type="ORF">SAMN05428934_106162</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY94260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11565"/>
    <dbReference type="EnsemblBacteria" id="AQP45356">
        <property type="protein sequence ID" value="AQP45356"/>
        <property type="gene ID" value="RPIT_11565"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY94260">
        <property type="protein sequence ID" value="SDY94260"/>
        <property type="gene ID" value="SAMN05428934_106162"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11565"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="1">
        <location>
            <begin position="61"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY94260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="211" mass="23432" checksum="9644AF8CE681D88A" modified="2017-04-12" version="1">MSEDPTAPTVGVGPHPLPWPTGDHLDPELLAEGDRRNVVDRYRYWKLEAIVDDLDRTRVPLHVAIQNWEHDFNIGSMVRTANAFNVAAVHIVGKKRWNRRGAMVTDRYLHVVHHDDEASLFEHLERLGVTPVGVDNFEGSVPLEAERLPERCCLIFGSEGPGLTDDMVAGCDRLVAITQRGSTRSMNAGAAAAIAMYHWSLQHTGASVPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH05</accession>
    <name>A0A1Q2CH05_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zinc transporter, ZIP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_11855</name>
        <name evidence="7" type="ORF">SAMN05428934_106103</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11855"/>
    <dbReference type="EnsemblBacteria" id="AQP45408">
        <property type="protein sequence ID" value="AQP45408"/>
        <property type="gene ID" value="RPIT_11855"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92950">
        <property type="protein sequence ID" value="SDY92950"/>
        <property type="gene ID" value="SAMN05428934_106103"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11855"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY92950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="268" mass="28290" checksum="44231555068FA4AC" modified="2017-04-12" version="1">MLTALIVSLLAGLATSVGGLLVVQRRELGREFLAVALAFAAGAMLLISFMQVLPLGIDWMAESHTLATAEALVFAAFFAGIALVLVIDRLLPASLNPSEIEGREGAMDFHDATRNKRLLRSGLLVALVLGLHNFPEGMATFFTSYHDPAVGVALAIAVAIHNVPEGIAVAAPVYAATGSRSRAFWWATVSGLTEPLGALLAAALVSWLVPESVLGMFYGMVAGMMVFLALDEMLQASWRYQTAKHQTIYGMLAGMATVATSLVLFAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH37</accession>
    <name>A0A1Q2CH37_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_11650</name>
        <name evidence="6" type="ORF">SAMN05428934_106145</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11650"/>
    <dbReference type="EnsemblBacteria" id="AQP45370">
        <property type="protein sequence ID" value="AQP45370"/>
        <property type="gene ID" value="RPIT_11650"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93842">
        <property type="protein sequence ID" value="SDY93842"/>
        <property type="gene ID" value="SAMN05428934_106145"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11650"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="5"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY93842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="341" mass="36490" checksum="CB451D428E4BAEEB" modified="2017-04-12" version="1">MKNRPTMNDVAAEAGVSQATVSMVLNQSQAGRVSAETSQRVLDAAKKLGFRTNVHAKVLREGKSRMIGLIGDEVATTPFAGEMILGAQQEAWRRGHVLLTVDTAGDSRLEQAAISMMQSYRVAGVIYAAMYHRRLDVPTGLSGIPTVCLNAQDPAGSVTSVFPDEEAGGRAAARVLLEAGHRDIGMINIGPEGSTLPAASGRLKGFIETLDAEGVPFRAEWLRFGTGGYEDGLRGGLELLTLEQRPRAIFCANDRTALGLYYAAERLGLSVPDDVSVVGFDNQALLTPMFQPALTTFQLPLAEMGRLAVAEVLNRGSETKRLAVECSPQLRQSVASVKVYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH65</accession>
    <name>A0A1Q2CH65_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Threonine synthase</fullName>
            <ecNumber evidence="6">4.2.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">RPIT_12105</name>
        <name evidence="14" type="ORF">SAMN05428934_10655</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + O-phospho-L-homoserine = L-threonine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10840"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.2.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the threonine synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.1" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY91861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12105"/>
    <dbReference type="EnsemblBacteria" id="AQP45454">
        <property type="protein sequence ID" value="AQP45454"/>
        <property type="gene ID" value="RPIT_12105"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY91861">
        <property type="protein sequence ID" value="SDY91861"/>
        <property type="gene ID" value="SAMN05428934_10655"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12105"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004795">
        <property type="term" value="F:threonine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029144">
        <property type="entry name" value="Thr_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037158">
        <property type="entry name" value="Thr_synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004450">
        <property type="entry name" value="Thr_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14821">
        <property type="entry name" value="Thr_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00260">
        <property type="entry name" value="thrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Thr_synth_N" evidence="12">
        <location>
            <begin position="2"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="PALP" evidence="11">
        <location>
            <begin position="100"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="10">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR604450-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP45454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY91861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="485" mass="53060" checksum="9A7F166814B36BE5" modified="2017-04-12" version="1">MRYISTRDTEGRAGKGFSDILLEGLAADGGLYLPESYPQVDAATLETWRELLAHQGYSALAFEIVRLFVDDIPEADLRGIVTRAYDPVKFLDPAVVPVTRLSDGLWLAHLSNGPSAAFKDMAMQLLGELFAYELARRGETITIVGATSGDTGSSAEYALKDKPGVHVFMLSPRGRMTPFQQAQMFSIDDERIVNIAVDGVFDDCQDLVKEINADAAFKARYRIGAVNSINWARLMAQVVYYFAAWLQVSDGGPVSFSVPSGNFGNIAAGHIARQMGLPIHRLILATNENNVLEEFFRTGVYRVRGSAETLATSSPSMDISKASNFERFVFDLLGRDAARLRELFVDDLADGEFDLSGADEFRGQLDRFGFVSGTSTHQDRLAQIRRVYEADKVTIDPHTADAVQVAQTSGVQGPIVVLETALPVKFADTIVEAIGMVPPRPARFDGIEDLPRHVVDLPCDVDALRSLIAERMPEFSGGASEEPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHB4</accession>
    <name>A0A1Q2CHB4_9ACTN</name>
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        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">SAMN05428934_104191</name>
    </gene>
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    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 3">RP1T</strain>
        </source>
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    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP45516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45516">
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        <property type="gene ID" value="RPIT_12475"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY80320">
        <property type="protein sequence ID" value="SDY80320"/>
        <property type="gene ID" value="SAMN05428934_104191"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12475"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY80320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="133" mass="14247" checksum="EC401888F7C0B68D" modified="2017-04-12" version="1">MATLEHRNHARSFLRKAEEYLASAEANLNAERYTVAAGDAIHAGICAKDAIVTQLTGSTVKGKDHALAAKELRRALGQRPDAAGAEKGLRELVSNKADVEYGVSLMSAVKAEALVRRARSLVEIAVRVVRLNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHE1</accession>
    <name>A0A1Q2CHE1_9ACTN</name>
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        <submittedName>
            <fullName evidence="4">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_12530</name>
        <name evidence="4" type="ORF">SAMN05428934_104180</name>
    </gene>
    <organism evidence="3 5">
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
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    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
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    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP45527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY80024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12530"/>
    <dbReference type="EnsemblBacteria" id="AQP45527">
        <property type="protein sequence ID" value="AQP45527"/>
        <property type="gene ID" value="RPIT_12530"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY80024">
        <property type="protein sequence ID" value="SDY80024"/>
        <property type="gene ID" value="SAMN05428934_104180"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Phage_holin_4_2"/>
    </dbReference>
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        <property type="entry name" value="PTHR37309"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Phage_holin_4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544507" evidence="2">
        <location>
            <begin position="28"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY80024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="125" mass="12664" checksum="9BF41B782A3CECBD" modified="2017-04-12" version="1">MNFALRILATAVATALAVWLIPGISLTADTTANKALTLVAVAAILGVVNAVVKPFTQAISACLIVLTLGLFLLVINALMLMLTSWLSGQLGLGFEVDGFVSALLGSIVISLVASVVASLLGAGKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHG6</accession>
    <name>A0A1Q2CHG6_9ACTN</name>
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        <name evidence="1" type="ORF">RPIT_12660</name>
        <name evidence="2" type="ORF">SAMN05428934_104154</name>
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    <organism evidence="1 3">
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    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY79281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45551">
        <property type="protein sequence ID" value="AQP45551"/>
        <property type="gene ID" value="RPIT_12660"/>
    </dbReference>
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        <property type="gene ID" value="SAMN05428934_104154"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12660"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR008792">
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    </dbReference>
    <dbReference type="Pfam" id="PF05402">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY79281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="85" mass="8894" checksum="7E3CFA0369289FFB" modified="2017-04-12" version="1">MIRRTDLTDFLVVDGESVAILNETVYRLGHVATAILDALAEPTTLPALATTLEAQFGAPPSGSLEDAVRSQLDELAAVGLVSIDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHH7</accession>
    <name>A0A1Q2CHH7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter substrate-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Cellobiose-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12740</name>
        <name evidence="3" type="ORF">SAMN05428934_104139</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY78835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12740"/>
    <dbReference type="EnsemblBacteria" id="AQP45564">
        <property type="protein sequence ID" value="AQP45564"/>
        <property type="gene ID" value="RPIT_12740"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY78835">
        <property type="protein sequence ID" value="SDY78835"/>
        <property type="gene ID" value="SAMN05428934_104139"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12740"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544513" evidence="1">
        <location>
            <begin position="30"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY78835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="434" mass="46806" checksum="2E5BAC62867608A2" modified="2017-04-12" version="1">MRAAIRNIAAVACVGALLSACSTGTTPEATQSDAPSADPNQEVTLSVATFNEFGYEELFEEYMADNPNVTIEHRKAATSNEARDNMNTRLAAGSGLADIEAIEVDWLTELMQYSDKFTDLADPELDGRWLDWKVEAVTTEDGKVIGYGTDVGPEAICYRADLFEQAGFPTDREEVADLLEGDWDTYFNVGKDFVANSDGVAWFDSASATFQGMVNQVENPFENSDGTPIPLAENDEIKSIYDDIATAAVDDNLSAGLAQWSEDWTNAFQTDKFATMLCPGWMLGVIEGNAEGVEGWDIANVFPGGGGNWGGSYLTVPAQSENPEHAKKLAAWLTAPEQQIKAFESKGTFPSQVEALEDPALLDSTNAFFNDAPTGQILADRANAIEVQPFKGPNYFALAQLVTDALNRLDVEGTDDAASSWDKAVEAYAALGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHJ1</accession>
    <name>A0A1Q2CHJ1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS transporter, PPP family, 3-phenylpropionic acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_12620</name>
        <name evidence="8" type="ORF">SAMN05428934_104162</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY79524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45543">
        <property type="protein sequence ID" value="AQP45543"/>
        <property type="gene ID" value="RPIT_12620"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY79524">
        <property type="protein sequence ID" value="SDY79524"/>
        <property type="gene ID" value="SAMN05428934_104162"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12620"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024989">
        <property type="entry name" value="MFS_assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12832">
        <property type="entry name" value="MFS_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="127"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="336"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="143"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY79524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="389" mass="40782" checksum="54037677245DD76F" modified="2017-04-12" version="1">MRLSTTRYAALQSAYWSAFCLAIMFASVFLLSKGLTNTQIGIVVATGGAISAVAQPIVAGAAEGSRVPLRVWISALTALMIVVAAALFIPGLPWLLTAVFFGFQILTIQLILPLVNALGMAVLNAGIAMNFGVARAAGSAVFAVVSVGAGSLVAAFDTMVIPLLAIGFQALMILFALTFTYRQPALPHVDTDDEAHVAPTAHAPLTLVQRRKFTLLLVGVALSMTSHNLINAFLFQTMTYHGGGAEEMGTAVMIAALCELPTMALWSWIVTKWSSGLMLKVAGVFFAVKNLATWLAGSVGALYFAQGLQLLAFAVLVPASIYYVNKLMPPQDRVKGQAYMTMTHTLGTVIGSLSGGFILDAAGVPTMLLFGTAVATVGAVLTIVSAEHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHL6</accession>
    <name>A0A1Q2CHL6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Carbonate dehydratase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">Cu+-exporting ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_12950</name>
        <name evidence="11" type="ORF">SAMN05428934_10497</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12950"/>
    <dbReference type="EnsemblBacteria" id="AQP45601">
        <property type="protein sequence ID" value="AQP45601"/>
        <property type="gene ID" value="RPIT_12950"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY77684">
        <property type="protein sequence ID" value="SDY77684"/>
        <property type="gene ID" value="SAMN05428934_10497"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12950"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="110"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="342"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="673"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="696"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="9">
        <location>
            <begin position="4"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP45601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY77684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="729" mass="75675" checksum="EB743CC8C8B08F54" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHN3</accession>
    <name>A0A1Q2CHN3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">N-acylglucosamine 2-epimerase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Sulfoquinovose isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_12845</name>
        <name evidence="2" type="ORF">SAMN05428934_104118</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY78230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12845"/>
    <dbReference type="EnsemblBacteria" id="AQP45583">
        <property type="protein sequence ID" value="AQP45583"/>
        <property type="gene ID" value="RPIT_12845"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY78230">
        <property type="protein sequence ID" value="SDY78230"/>
        <property type="gene ID" value="SAMN05428934_104118"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12845"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY78230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="401" mass="44864" checksum="104335127BD5C923" modified="2017-04-12" version="1">MSHLDELRRHRDELLDFYQPHVCLESGGYAYLDDVGRPLPDQGAQLWLNARMLHCFSIATALGRPGAADVVEHGLAHLHGGAGQDLIHGGWYATAGGSNPSDAKELYGQAHVVLAASSAAMAGFTEGRALLDEALDLIDRRYWREGDGRAVEAYDRTFSRLDPYRGQNANMHLTEALINAYEATGEAVLLQRAVRIAGHIAGRAASPDEGAWRLPEHFDEDWNVVWEFNKDEPRHPFRPYGSQPGHWLEWAKLLLQLRGLGVHEPWLLPAAEHLFAGAFKDAWRGTGGFVYTVDWDGAPVVEERFFWEPAEGMGAARLLELHTDDDRYAEAYGKLWGYVVDHFVDHESGSWFPELDAEQKPVTHTWAGKPDLYHAFQATLYAEVPAHQGLARWASTQASRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI03</accession>
    <name>A0A1Q2CI03_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13520</name>
        <name evidence="4" type="ORF">SAMN05428934_11195</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SorC transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ13296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13520"/>
    <dbReference type="EnsemblBacteria" id="AQP45703">
        <property type="protein sequence ID" value="AQP45703"/>
        <property type="gene ID" value="RPIT_13520"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ13296">
        <property type="protein sequence ID" value="SDZ13296"/>
        <property type="gene ID" value="SAMN05428934_11195"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13520"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007324">
        <property type="entry name" value="Sugar-bd_dom_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04198">
        <property type="entry name" value="Sugar-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH crp-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ13296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="323" mass="35331" checksum="BFFB6138AAA59CC1" modified="2017-04-12" version="1">MDRASDDLLTVARMYYVQSETMDAIAHHLGVSRSTVSRLLKEARERGLVRVSIVDPDRPMNRMAELFSKHFNVTAHLVHVRPGASSIFRLDQVARMAAGILSDTVEDGDTVGVAWGTTTSAVATHLRPRDLTGVTVIGLNGGANHQTTGLPYVGSILHRFATAFRGQEQLLALPAFFDDPATREAMWREQSTRHILTVRANCNVAIFGVGGLNSELQSHVYASNYLGADDLKHLREQNVVGDVCTVMLREDGSYRDLAINKRATGMTPAELQRIPRRICVVSGLSKASPVLGALRARVATDLVIDEETARAVLNLMKPGIRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI45</accession>
    <name>A0A1Q2CI45_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">DNA-binding response regulator, OmpR family, contains REC and winged-helix (WHTH) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_14105</name>
        <name evidence="7" type="ORF">SAMN05428934_1122</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ14180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14105"/>
    <dbReference type="EnsemblBacteria" id="AQP45796">
        <property type="protein sequence ID" value="AQP45796"/>
        <property type="gene ID" value="RPIT_14105"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ14180">
        <property type="protein sequence ID" value="SDZ14180"/>
        <property type="gene ID" value="SAMN05428934_1122"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14105"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="128"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="128"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ14180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="221" mass="24114" checksum="05A5D43B3D25C0A3" modified="2017-04-12" version="1">MSTILIIEDEPRISGFIAKGLKAAGFTSHQTASGAEGVALAVHGNFDLVILDVGLPDIDGFEVLERIRGQGVSVPVIMLTARSSVADRVAGLEGGADDYVPKPFSFEELLARIRLRLRADSSAGSASATQLSHNGLVLDFRTRKAQVDGEWVDLSAREFTLAETFLRNPGQVLSREQLLSNVWGYDFDPGSNVVDVYVRYLRGKLGKDRFETVRGMGYRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIF3</accession>
    <name>A0A1Q2CIF3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Single-strand binding protein family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_14635</name>
        <name evidence="4" type="ORF">SAMN05428934_10988</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14635"/>
    <dbReference type="EnsemblBacteria" id="AQP45891">
        <property type="protein sequence ID" value="AQP45891"/>
        <property type="gene ID" value="RPIT_14635"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06279">
        <property type="protein sequence ID" value="SDZ06279"/>
        <property type="gene ID" value="SAMN05428934_10988"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14635"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ06279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="119" mass="13118" checksum="6EA9536712403DD9" modified="2017-04-12" version="1">MTSYINFTGNLAKAPELRTDKNGRPYTFARVIRTDRVNKGGEFEDGGTEGYDVAVWGADAEALCDLAERCGNVRVNVAGEEVLDTYTNDEGVTRTVRKVNDAEITVSLRGQTVTVERRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIG6</accession>
    <name>A0A1Q2CIG6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14855"/>
    <dbReference type="EnsemblBacteria" id="AQP45926">
        <property type="protein sequence ID" value="AQP45926"/>
        <property type="gene ID" value="RPIT_14855"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14855"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006938">
        <property type="entry name" value="DUF624"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04854">
        <property type="entry name" value="DUF624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="137" mass="14501" checksum="4F37F1CB436F430D" modified="2017-04-12" version="1">MVDPNSRTWQALGLAADVVVVNALTIVCSLPVVTAGAALSAAHGTLLEMVREEGAKPARTYFSYFTRTWRTATLGWLLLLAVGSVLGWEYWALGRMDGGAALVAQAGVLAGAILVTLWAVWFFPLASRGRGSPAPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIJ4</accession>
    <name>A0A1Q2CIJ4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter substrate-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Carbohydrate ABC transporter substrate-binding protein, CUT1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14840</name>
        <name evidence="3" type="ORF">SAMN05428934_10952</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14840"/>
    <dbReference type="EnsemblBacteria" id="AQP45924">
        <property type="protein sequence ID" value="AQP45924"/>
        <property type="gene ID" value="RPIT_14840"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05586">
        <property type="protein sequence ID" value="SDZ05586"/>
        <property type="gene ID" value="SAMN05428934_10952"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14840"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544530" evidence="1">
        <location>
            <begin position="26"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ05586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="447" mass="48703" checksum="8AF81C8DAE31A2FA" modified="2017-04-12" version="1">MKNLKRSIALLAVAALSVGALAACGDDEGASGDAEGSVYFLNWKPESEATYGEIAEKYTEETGVEVKVVTAASGTYEQTLQAEMTKSDAPTLFQINGPVGLVSWQEYAADLGETDFAKDLSDPGLALTGEDGTVYGVPLAVEGFGIIYNDAIMRDYFEMDGAKAASMDEINNFDKLKEVTDDMQARKADLGIDGVFASTSLATGEAWRWQTHLFNTPLYHEYQEKGITDAEEIEFTYSNEFKNIFDLYLTNSTVEKTLAPSKTVTDSMAEFATGKAAMVQNGNWAWSQIKDIEGNAVAEEDIKFLPIYSGVEGEEDLGINVGTEAFMAVNSQATEADQQATIDFVNWLFTDEEGMNYVTEDLGFIAPFKSFGDRTPADPLAKEINRYISDDSLTAVPWVFTTMPSAKFKDDFAQLLAQYASGNLEWAEVEEAVVANWATEKAAVGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIN6</accession>
    <name>A0A1Q2CIN6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_03515</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03515"/>
    <dbReference type="EnsemblBacteria" id="AQP45996">
        <property type="protein sequence ID" value="AQP45996"/>
        <property type="gene ID" value="RPIT_03515"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03515"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="166"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="51"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="247" mass="25297" checksum="A554BB70519B70B8" modified="2017-04-12" version="1">MPAAVAVIAVAALWLAVTTLGAIDPLYLPNPLDVVGRMVTQAETGVALRYLAPTLAAALLGAAIAVAVALPLGVVVTHSRLLASIVEPVVAISQTVPLVALAPLLVLWIGYGTVPIAVLCAIVAFFPMVTTTIVGFRSLDMRVVENALLDGANSWQRLIHIEGPMAAPAVLAGVRGGVVLAMTGAVVGELVMGGAGLGTLLTLTREAADTAGMFAVVAWISLSAMVLYGFIQMLERAAVTRLQGEST</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIS0</accession>
    <name>A0A1Q2CIS0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative lipid II flippase FtsW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_04025</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04025"/>
    <dbReference type="EnsemblBacteria" id="AQP46007">
        <property type="protein sequence ID" value="AQP46007"/>
        <property type="gene ID" value="RPIT_04025"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04025"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013437">
        <property type="entry name" value="FtsW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001182">
        <property type="entry name" value="FtsW/RodA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474">
        <property type="entry name" value="PTHR30474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01098">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02614">
        <property type="entry name" value="ftsW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012523921" evidence="8">
        <location>
            <begin position="33"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="296"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP46007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="387" mass="41010" checksum="6E46155192B4947E" modified="2017-04-12" version="1">MAPYYFIAGSVTILVVIGSLMVLSASSVLAQATQDGPYYFAIRQLQFLGAGLVFAIALSRTPPALLRRIGWLVWALAVVLLILVQTPLGVTVNGNTNWLEIGPVQFQPSEFAKLALIVWCGTVFHLKRGRLHEPAQLAVPLVPLGGLILALVLAGRDLGTGLIVGLIMVLILWFIGTSLRVLIPMGAAALGLVVLLVYGSGNRMSRISVFLDPQSNTDLSSQPMAALYALASGGWWGLGLGAGKQKWGGLKDGAHTDFIFAVIGEELGLFGVLLVVGLFALLGWAGLEVAMRSDKMFNRVVAAGITGWFLVQAIINIFVVLHLLPVLGVPLPFISYGGSALMAGLMATGVLMALARDTPSARAYLATRAPRAARPRMTSVMAATKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIS3</accession>
    <name>A0A1Q2CIS3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Threonine--tRNA ligase</fullName>
            <ecNumber evidence="10">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Threonyl-tRNA synthetase</fullName>
            <shortName evidence="10">ThrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">thrS</name>
        <name evidence="12" type="ORF">RPIT_05690</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl-tRNA(Thr)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="10"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05690"/>
    <dbReference type="EnsemblBacteria" id="AQP46038">
        <property type="protein sequence ID" value="AQP46038"/>
        <property type="gene ID" value="RPIT_05690"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05690"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00184">
        <property type="entry name" value="Thr_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="PTHR11451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 10" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="11">
        <location>
            <begin position="273"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="398"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="530"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP46038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="663" mass="73863" checksum="2EB946685C33A450" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIV1</accession>
    <name>A0A1Q2CIV1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_05940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05940"/>
    <dbReference type="EnsemblBacteria" id="AQP46041">
        <property type="protein sequence ID" value="AQP46041"/>
        <property type="gene ID" value="RPIT_05940"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05940"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012908">
        <property type="entry name" value="PGAP1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07819">
        <property type="entry name" value="PGAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP46041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="208" mass="22074" checksum="B074A2683959E96B" modified="2017-04-12" version="1">MLDRTPPDAYDNGDRVPVIVLPGIWEPWRFMLPLAKVLHAEGHPIYPVPGLRLNGAPLDASAEKVAEALSEHDAPRVVLVAHSKGGLVGKQLMLHPKVGHRVAGLVALCSPFGGSTLSLPVLARTPLGLFSPANSALTALAAEQAVNAKIVSIGSSYDEMVPNGTHLEGAHNITLEMAGHFRPLVSPSAQQLVLQEVRRFDTSPDPGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIV2</accession>
    <name>A0A1Q2CIV2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine protein phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_07185</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallophosphoesterase superfamily. YfcE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07185"/>
    <dbReference type="EnsemblBacteria" id="AQP46068">
        <property type="protein sequence ID" value="AQP46068"/>
        <property type="gene ID" value="RPIT_07185"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07185"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="2">
        <location>
            <begin position="22"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="296" mass="34522" checksum="89DA0EC54BF60B11" modified="2017-04-12" version="1">MTRLTEAYRDARVELIDDTSRYVIMSDCHRGDGSKSDEFLKNKNSFTAALDHYWKNGFTYVEAGDGDELWEHDFKHIVRANRAVWEQLLQFHGAGRLIRMWGNHDLDLRDPRFVRQHLWTAKDAETGEVGPFFDGLEPVEAVVFRHRTTGQDILLVHGHQGDFPNDQGWRFSRLMMRVFWRYAHAFGFHSPTSPVANAEKRHKVERNYVKWIRQNRMALICGHTHRERFPREDEMPYFNSGSCVYPSHITALEIADGTIALVRWRVDPNEDAILQVTRRVVKGPEPLSTFDLRNSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ08</accession>
    <name>A0A1Q2CJ08_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09140"/>
    <dbReference type="EnsemblBacteria" id="AQP46101">
        <property type="protein sequence ID" value="AQP46101"/>
        <property type="gene ID" value="RPIT_09140"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09140"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010359">
        <property type="entry name" value="IrrE_HExxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06114">
        <property type="entry name" value="Peptidase_M78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="21"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="383" mass="43181" checksum="BB610715FF740EEC" modified="2017-04-12" version="1">MAHDGNVDLAGVARMFDPARLAQARRISKMSKADLHRKVGVSAAAIGQYERGEVRPRAETVAALATALGVPPGFFALGRPRVQVDIAEASFRRLRSTTVTQQQQATAYVEQAWELSCYLEESVEFPELDLPAWAHADSFDVPDPATAARAMRQHWLLGTGPIEHLVYQLEQHGILTVFFSMKEDASLDEKSRIDAFSTIALPRPMIVLTPDKANDVMRHRFSAAHELGHIVLHHGRQGTDSQLERQADMFAAEFLTPRDVIRDQLPRRINFNRYEELSQLWGVSINSLIFRSRELDLISESTARRAYITLNGIARRPMPVHDYPGERPELLKSALELLDQAGVPLTQVAEDLQMTPRHIRRLADIDDPQPKLTLVNDRPDRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ75</accession>
    <name>A0A1Q2CJ75_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11065"/>
    <dbReference type="EnsemblBacteria" id="AQP46133">
        <property type="protein sequence ID" value="AQP46133"/>
        <property type="gene ID" value="RPIT_11065"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11065"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="346" mass="35589" checksum="33108BF3BDEBE16D" modified="2017-04-12" version="1">MRTGLVLLAGVSLLTGLNAGLLRLGVWAPVASTRLGDLHGPVMVLGFMGSLIALERAQALRNPLAYLAPALLAAGSVALIAGAPLLLGKLLLLDGALAFTAVAIALWRRAPLGLVAAQAVGTAFAALAAGLWLVTDLAVILPLLAAFLVIMIASERAELAQLTMGRRAVPALLAATVVVSASAVATLVAPDWGARALGLGCLLVAVWLIRDDVGRRMIRSTGLRRFNAAALLLGNLWLGVAGVVWAVGGQPSASGAYDAVIHGVFLGFGMSMIMAHAPIIFPTVLGRPLPYRPAMWGPLALLHLGMATRLTGGLAAIAPLYRLGGVLTVLSVLAFAITVIYSVVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ82</accession>
    <name>A0A1Q2CJ82_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytoplasmic protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">DNA-binding transcriptional regulator, FrmR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_13610</name>
        <name evidence="5" type="ORF">SAMN05428934_11177</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CsoR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13610"/>
    <dbReference type="EnsemblBacteria" id="AQP46171">
        <property type="protein sequence ID" value="AQP46171"/>
        <property type="gene ID" value="RPIT_13610"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12994">
        <property type="protein sequence ID" value="SDZ12994"/>
        <property type="gene ID" value="SAMN05428934_11177"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13610"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003735">
        <property type="entry name" value="Metal_Tscrpt_repr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038390">
        <property type="entry name" value="Metal_Tscrpt_repr_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33677">
        <property type="entry name" value="PTHR33677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02583">
        <property type="entry name" value="Trns_repr_metal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP46171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ12994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="86" mass="9436" checksum="5483585812A4BC6A" modified="2017-04-12" version="1">MQLDQDEMTAVVKRLKRAQGQLGGVIRMIEEGRGCEEIVTQLAAVSKAVDRAGFTTISIGLRQCVERPEDGNLDTAKMEKLFLSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJB4</accession>
    <name>A0A1Q2CJB4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF3566 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_13675</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13675"/>
    <dbReference type="EnsemblBacteria" id="AQP46173">
        <property type="protein sequence ID" value="AQP46173"/>
        <property type="gene ID" value="RPIT_13675"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13675"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021949">
        <property type="entry name" value="DUF3566_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12089">
        <property type="entry name" value="DUF3566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010315655" description="DUF3566 domain-containing protein" evidence="2">
        <location>
            <begin position="43"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3566" evidence="3">
        <location>
            <begin position="72"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP46173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="190" mass="19832" checksum="338CE711BFC1EB5A" modified="2017-04-12" version="1">MTPSLSERAVSAAKAWATRPVPPVVPAAVPTAVPPTTTPARAAGDVAEASVARSATTADQRARPVRSTRRTRKARLRLARLDPWSVMKTTFLFAIAFGIMLVVATFVVWSVLAGSGAIQAANEFLNTLLGDQDTTFDIGGILSLNRILGFAAVVAAIDVVILTALATLAAFLYNLAATVMGGLEVTLAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBF6</accession>
    <name>A0A1Q2CBF6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00200</name>
        <name evidence="4" type="ORF">SAMN05428934_1094</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ04595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00200"/>
    <dbReference type="EnsemblBacteria" id="AQP43436">
        <property type="protein sequence ID" value="AQP43436"/>
        <property type="gene ID" value="RPIT_00200"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ04595">
        <property type="protein sequence ID" value="SDZ04595"/>
        <property type="gene ID" value="SAMN05428934_1094"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00200"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02857">
        <property type="entry name" value="E_set_CDase_PDE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004185">
        <property type="entry name" value="Glyco_hydro_13_lg-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="2">
        <location>
            <begin position="129"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ04595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="602" mass="66698" checksum="7E78C2E8740554D2" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBI3</accession>
    <name>A0A1Q2CBI3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Prephenate dehydratase</fullName>
            <shortName evidence="10">PDT</shortName>
            <ecNumber evidence="3 10">4.2.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pheA</name>
        <name evidence="13" type="ORF">RPIT_00415</name>
        <name evidence="14" type="ORF">SAMN05428934_10537</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:21648"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="4.2.1.51"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.51" evidence="3 10"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY84414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00415"/>
    <dbReference type="EnsemblBacteria" id="AQP43466">
        <property type="protein sequence ID" value="AQP43466"/>
        <property type="gene ID" value="RPIT_00415"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY84414">
        <property type="protein sequence ID" value="SDY84414"/>
        <property type="gene ID" value="SAMN05428934_10537"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00415"/>
    <dbReference type="UniPathway" id="UPA00121">
        <property type="reaction ID" value="UER00345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004664">
        <property type="term" value="F:prephenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008242">
        <property type="entry name" value="Chor_mutase/pphenate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001086">
        <property type="entry name" value="Preph_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018528">
        <property type="entry name" value="Preph_deHydtase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00800">
        <property type="entry name" value="PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001500">
        <property type="entry name" value="Chor_mut_pdt_Ppr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00857">
        <property type="entry name" value="PREPHENATE_DEHYDR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00858">
        <property type="entry name" value="PREPHENATE_DEHYDR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51171">
        <property type="entry name" value="PREPHENATE_DEHYDR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 10" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate dehydratase" evidence="11">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="12">
        <location>
            <begin position="193"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="site" description="Essential for prephenate dehydratase activity" evidence="9">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001500-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP43466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY84414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="300" mass="31989" checksum="4023ABA568A27290" modified="2017-04-12" version="1">MLGYFGPAGTFTHQALRTISAEDAVAFASVREALEAVREGQLLGAVVPIENSVEGGVSATLDELIAGEPLAIRREIVIAVEFGLYVRPGTQLHEVREVLTHGHAAAQCRDWLALMVPQATVTEAGSTAGAAAEVARPESRYDAAVCARVAGQLYGLTELAYQIEDNPGAVTRFVEVGLAGSVPERTGADKTTLVAYMREDHAGALLEILEQFAVRGVNLSRIESRPTKTTLGSYCFSIDVEGHLDDKRVAEALEGLHRVCPRVHFLGSYPRADGRRPAVGYGSTDEEFDAAAEWVASLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBJ2</accession>
    <name>A0A1Q2CBJ2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4440 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00075</name>
        <name evidence="3" type="ORF">SAMN05428934_10930</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00075"/>
    <dbReference type="EnsemblBacteria" id="AQP43415">
        <property type="protein sequence ID" value="AQP43415"/>
        <property type="gene ID" value="RPIT_00075"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05166">
        <property type="protein sequence ID" value="SDZ05166"/>
        <property type="gene ID" value="SAMN05428934_10930"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00075"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027843">
        <property type="entry name" value="DUF4440"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14534">
        <property type="entry name" value="DUF4440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4440" evidence="1">
        <location>
            <begin position="13"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ05166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="123" mass="13412" checksum="EE2A032E8CA8FC74" modified="2017-04-12" version="1">MATLDINHLLSTEHNGWLALSEGTGASFYDALLTDDAVMVLVGGGILSRDEAVASLENSPTWDKYEITDPRLIEVGPDAAALVYRASALRGTEDTFRAAMTSLYRVVDGRLRLAIYQQTLITH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBL1</accession>
    <name>A0A1Q2CBL1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glyco_trans_2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43496">
        <property type="protein sequence ID" value="AQP43496"/>
        <property type="gene ID" value="RPIT_00575"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00575"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="35"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="394" mass="43216" checksum="7949EDEE4F46CCBB" modified="2017-04-12" version="1">MADHHAPAGTEQDDPGLDGTDHRIPSGPADGLRISVVIPCHLALPFLPSCVDTLTSQTLPRDDFEAIFVFNGPEDGGYDVARDLLAESGLHHQLARSSRGISPARNVGASVARAPWLTLLDVDDSLTPNYLEAMLASATDETVVPVAGIVDVGDDGVEMSSHINETILAREGIVDPVDLIRPLSISTLKLVPIAAMRRHPFDPAMRSGEDVALWTDLFEAEGLRFDTTPAFRGARYRRAVREHSHGRQGMTWDFMVVQRLDVIEELTRQQLRGGDLGAIRTYLINTQADFIARYLTEHPDSRPARLVGAGRGGPRHRAGRADDLRDLPDDALPPGRRRAEGSHPPAARGRPLHPRAGQRGEPQRARDRRGLAHRRHPSAHARRGHRDHPAAAYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBM6</accession>
    <name>A0A1Q2CBM6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Arginine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Arginyl-tRNA synthetase</fullName>
            <shortName evidence="9">ArgRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">argS</name>
        <name evidence="13" type="ORF">RPIT_00650</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg)</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00650"/>
    <dbReference type="EnsemblBacteria" id="AQP43509">
        <property type="protein sequence ID" value="AQP43509"/>
        <property type="gene ID" value="RPIT_00650"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00650"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00671">
        <property type="entry name" value="ArgRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00123">
        <property type="entry name" value="Arg_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005148">
        <property type="entry name" value="Arg-tRNA-synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="PTHR11956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03485">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM01016">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="SSF55190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arg_tRNA_synt_N" evidence="12">
        <location>
            <begin position="2"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="DALR_1" evidence="11">
        <location>
            <begin position="429"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP43509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="544" mass="59173" checksum="B8FE33F8AAA162D2" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBP5</accession>
    <name>A0A1Q2CBP5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Propionyl-CoA--succinate CoA transferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Succinyl-CoA:acetate CoA-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_00755</name>
        <name evidence="6" type="ORF">SAMN05428934_105104</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetyl-CoA hydrolase/transferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00755"/>
    <dbReference type="EnsemblBacteria" id="AQP43529">
        <property type="protein sequence ID" value="AQP43529"/>
        <property type="gene ID" value="RPIT_00755"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86196">
        <property type="protein sequence ID" value="SDY86196"/>
        <property type="gene ID" value="SAMN05428934_105104"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00755"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008775">
        <property type="term" value="F:acetate CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003986">
        <property type="term" value="F:acetyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006083">
        <property type="term" value="P:acetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006084">
        <property type="term" value="P:acetyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019679">
        <property type="term" value="P:propionate metabolic process, methylcitrate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026888">
        <property type="entry name" value="AcetylCoA_hyd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038460">
        <property type="entry name" value="AcetylCoA_hyd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003702">
        <property type="entry name" value="ActCoA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017821">
        <property type="entry name" value="Succinate_CoA_transferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13336">
        <property type="entry name" value="AcetylCoA_hyd_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02550">
        <property type="entry name" value="AcetylCoA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03458">
        <property type="entry name" value="YgfH_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="333"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="active site" description="5-glutamyl coenzyme A thioester intermediate" evidence="2">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
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    <feature type="binding site" evidence="3">
        <location>
            <position position="384"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
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        <location>
            <position position="388"/>
        </location>
        <ligand>
            <name>CoA</name>
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        </ligand>
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            <position position="408"/>
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        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43529.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY86196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="504" mass="54670" checksum="97DF23477DAD6ABB" modified="2017-04-12" version="1">MSGRIRSEAFKSKVMSAVDAAAIVENGWNIGFSGFTGAGYPKVFPPALAERIREAHARGEEFMVSSWTGASTAPEHDGALAEVDGVRFRAPYQSDPVQRAKINDGTTYYSDIHLSHMPNLVAQGFLGDLDLAVIEVTAITEDGELVPSSSIGANRTYIEKAKRIILEVNEWQSEGLFGMHDVYYPIGNLPPHRPPLPITSTGDRIGTPTMKIDLDKVVAIIETDAPDRNTPFKDLDEDSLKIAGYFLDFLAAEVKAGRLPENLNPLQSGVGNIANAVLAGLLEGPFENITSYTEVIQDGMVDLIDSGKLAVASATAFSLSPTAAERMNDNAAHYAKKIVLRPMDVSNNPEAIRRMGVISCNGMIEADIYGNVNSTHVMGSRMQNGIGGSGDFTRNAFFSCFVSPSTAKGGAISAIVPMVNHVDHTEHDVSVIVTEQGLADLRGLAPRQRAEKIIENCAHPDYREPLREYVKLAHTKANGMHTPHDLRTALGWHVRFLETGTMKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBT3</accession>
    <name>A0A1Q2CBT3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01005</name>
        <name evidence="3" type="ORF">SAMN05428934_105152</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01005"/>
    <dbReference type="EnsemblBacteria" id="AQP43573">
        <property type="protein sequence ID" value="AQP43573"/>
        <property type="gene ID" value="RPIT_01005"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87486">
        <property type="protein sequence ID" value="SDY87486"/>
        <property type="gene ID" value="SAMN05428934_105152"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01005"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY87486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="237" mass="24881" checksum="B0215E490C07CB44" modified="2017-04-12" version="1">MTDISTPHISKNWRDDFIVAMRTQDASGEQIGDALATIDAHCAESGESAEEAFGDPTAYATTLVPEPASGSGLGASFLVGVLMGLLGLLIVPRAVDDWVIGTPFAVTIGDAVALAVVLGLTSVVMALPRRVLPWLAKVKYSVAGLLGVALMAVLVLAMLFLTDVVAEFSWLVALVIGVGLLVASVTSTWRDLSTPDPVADPRSADAPPRRTQWLTALTFPILTMLILGIDALFRLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBV4</accession>
    <name>A0A1Q2CBV4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized conserved protein, DUF427 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01095</name>
        <name evidence="3" type="ORF">SAMN05428934_105170</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01095"/>
    <dbReference type="EnsemblBacteria" id="AQP43588">
        <property type="protein sequence ID" value="AQP43588"/>
        <property type="gene ID" value="RPIT_01095"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87990">
        <property type="protein sequence ID" value="SDY87990"/>
        <property type="gene ID" value="SAMN05428934_105170"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01095"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007361">
        <property type="entry name" value="DUF427"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038694">
        <property type="entry name" value="DUF427_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04248">
        <property type="entry name" value="NTP_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transf_9" evidence="1">
        <location>
            <begin position="33"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY87990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="166" mass="17664" checksum="FCD0B46D9EAE8DB7" modified="2017-04-12" version="1">MVHRPKPDPVGPGQESVWDYPRPPTLRRCSLPIEVILGGEIVFRGNESLQVLETSHPPTYYLPRSGFVPGALTPAPGGSFCEWKGAAKYLDVHGGEATASAAAWYYPTPTAGFADLVDHVALYPGAMDACFVDGERVIPQPGGFYGGWITSSVAGPFKGTPGSMGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBW9</accession>
    <name>A0A1Q2CBW9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FRG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43597">
        <property type="protein sequence ID" value="AQP43597"/>
        <property type="gene ID" value="RPIT_01140"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01140"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014966">
        <property type="entry name" value="FRG-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08867">
        <property type="entry name" value="FRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00901">
        <property type="entry name" value="FRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FRG" evidence="1">
        <location>
            <begin position="9"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="221" mass="24824" checksum="1FBC0EE7CACFFE1E" modified="2017-04-12" version="1">MRDFLFESHDDQFVWRGVGNAAWCMVASLDRFADENFVRDRTALATRLQSLYREYSVELGDDAAELTDADLWALGQHWGLPTALLDWTRSPMVAMYFALTALSPGADYEDRNCVVYRLDASRPFLNRGGDVSVVAPPAGPWNQRLGAQRGVFVVGRLGTCFIQQLRDMGESDALRAYTISPTVRPAALRDLHTMMISDRKLFPDRAGILREVRSQAIHGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBY0</accession>
    <name>A0A1Q2CBY0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fucose permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_01275</name>
        <name evidence="8" type="ORF">SAMN05428934_1084</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ00962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01275"/>
    <dbReference type="EnsemblBacteria" id="AQP43616">
        <property type="protein sequence ID" value="AQP43616"/>
        <property type="gene ID" value="RPIT_01275"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ00962">
        <property type="protein sequence ID" value="SDZ00962"/>
        <property type="gene ID" value="SAMN05428934_1084"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01275"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="208"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ00962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="402" mass="41816" checksum="29CDA92418535DB9" modified="2017-04-12" version="1">MAPSREYARARVAVTLMFLLNGVGWSSLIPRYPELKNGLGLDDLSWGLVVGVGPLGGLLAGLFTARLMRRFNSSWVWLASTLVGLSMLNVSGNAVHWAMFAVGLITMAAMDALADIAMNAHGLRVQRGYGRSILNGLHGWWSVGAVIGGFLGSTAAQLGVPIWAQALVGFVAFAAAAFYARSLALPGPDAEPVTDPTAPTHGRGIPRRWLPRLLALGLLGASAGLIEDSGASWGGVYLESQFTVAPFVIGMAFVALQGSQMIGRFTGDALTNRIGPRAAVTQGMLIAAVGMGLAVAFPTPVTTLIGFACAGWGIATAIPGAMHAADELPGMLHGNGLTFVTWLMRVGFFVGPPLIGLVAQYVNLRWALLVIPVTAALGLLLSPALTPPRHAASPAADGGRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBZ3</accession>
    <name>A0A1Q2CBZ3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_01340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43626">
        <property type="protein sequence ID" value="AQP43626"/>
        <property type="gene ID" value="RPIT_01340"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01340"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="127" mass="13420" checksum="8D1F5AC9C88E796B" modified="2017-04-12" version="1">MPQPTPQGGPWTTVGETYSDAAAVAGASLLPESFRAFLGQRLGVEDEAGCTMTEVEVKTVHRDGFVFGSEAGTCGSAQTVWGITEGAWHYIVAFQDVMPCRDLELNGIPTGAEGLRCMDDSGAAKDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC10</accession>
    <name>A0A1Q2CC10_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01410"/>
    <dbReference type="EnsemblBacteria" id="AQP43637">
        <property type="protein sequence ID" value="AQP43637"/>
        <property type="gene ID" value="RPIT_01410"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01410"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="252" mass="25735" checksum="23A7D6A5FE4D282B" modified="2017-04-12" version="1">MTDSAPSTGRLDGGAGGAESTRSFLAEPHRAVWVIPLMMVIAAAVAGVEALGWVAAAGVAGGSMGWIAISAVRRRRAKQAAEQTAHAARLLASLLRAGQIPTVALAEAATECPSLARAAAASKLGSDVASELARSSRSPGRDGMGLMAAAWRVSERSGAPIAAVLATVAENLRHRRHLEALLETELAAARTSGRIMAALPFLALALGVLGGGDPLGFLLHHELGQWLILAGVVLTAGGVVWIDRLATARTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC21</accession>
    <name>A0A1Q2CC21_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Winged helix DNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_01505</name>
        <name evidence="2" type="ORF">SAMN05428934_10849</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43651">
        <property type="protein sequence ID" value="AQP43651"/>
        <property type="gene ID" value="RPIT_01505"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01864">
        <property type="protein sequence ID" value="SDZ01864"/>
        <property type="gene ID" value="SAMN05428934_10849"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01505"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009351">
        <property type="entry name" value="YcaQ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06224">
        <property type="entry name" value="HTH_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ01864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="359" mass="38667" checksum="AD0DEAD9004B3EA6" modified="2017-04-12" version="1">MPDQKRARLRLVAQSLVGPSFVSPEDAVSAFGAMQGQDLTGVIASAALRSRGGAESVLGAMDSGALVRGYPMRGTVFLLPGRDAAWITELCAGPALRASAARRHSLGLDETDLGKADEVATAALAASPLPRSQLLARWTEHGITTADGRGYHLLTTLIMMGRLIYGPWHDGEQLVALAEGWLPDGSDLAGRFNGERIDAVADLLRRYLLSHGPATIRDFAWWTKLALREIRAALPLIAGELETDGADEASYWAPGLQERAAGLGREPSRPLLLPGFDEFVLGYQDRLFAMTEAEHHRLVPGNNGVFKPSIVAGGRVRGVWRRAGRPGRRQLEVDGFGDLPASVAKRLPALFEDFPFPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC39</accession>
    <name>A0A1Q2CC39_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HPr family phosphocarrier protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Phosphocarrier protein HPr</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01270</name>
        <name evidence="3" type="ORF">SAMN05428934_1083</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ00941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01270"/>
    <dbReference type="EnsemblBacteria" id="AQP43615">
        <property type="protein sequence ID" value="AQP43615"/>
        <property type="gene ID" value="RPIT_01270"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ00941">
        <property type="protein sequence ID" value="SDZ00941"/>
        <property type="gene ID" value="SAMN05428934_1083"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01270"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00367">
        <property type="entry name" value="PTS-HPr_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000032">
        <property type="entry name" value="HPr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035895">
        <property type="entry name" value="HPr-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001020">
        <property type="entry name" value="PTS_HPr_His_P_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00381">
        <property type="entry name" value="PTS-HPr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00107">
        <property type="entry name" value="PHOSPHOCPHPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55594">
        <property type="entry name" value="SSF55594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01003">
        <property type="entry name" value="PTS_HPr_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51350">
        <property type="entry name" value="PTS_HPR_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00369">
        <property type="entry name" value="PTS_HPR_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HPr" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ00941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="89" mass="9369" checksum="D1680F8B239BB15C" modified="2017-04-12" version="1">MPSREATVASAVGLHARPASLFVQEVARLDVPVKIHKEGKRAVDAKSMLGVMTLGARCGDVVTLTAEGDGAEEALDRLVAFLEIDHDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC68</accession>
    <name>A0A1Q2CC68_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01750</name>
        <name evidence="3" type="ORF">SAMN05428934_10898</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01750"/>
    <dbReference type="EnsemblBacteria" id="AQP43690">
        <property type="protein sequence ID" value="AQP43690"/>
        <property type="gene ID" value="RPIT_01750"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02799">
        <property type="protein sequence ID" value="SDZ02799"/>
        <property type="gene ID" value="SAMN05428934_10898"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01750"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ02799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="287" mass="30598" checksum="78735487F5DC915A" modified="2017-04-12" version="1">MAENREELSKIPSQKQEWPGTESELKPAADHGQKTWTGRDRLTGKRALITGADSGIGRAVAVAFAKEGADVVVVDLPGSDDLEETRRLVEAEGRTCVALPLDLRTPEANKEAVETTVKELGGIDILVANAAYQMTHPDLDQFPDDQIHQTFETNVYSPFWLVKAADKHLSEGASVIFTASVQAYDPSEPLLDYAATKAAVTNLGMNLASLLGERGIRVNVVAPGPIWTPLIPATMPEKKVEGFGSDTPLGRAGDPIEVASAFVYLASDEASYVSGAVLGVTGGRPVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCB7</accession>
    <name>A0A1Q2CCB7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">8-oxo-dGTP diphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02045</name>
        <name evidence="3" type="ORF">SAMN05428934_1016</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY22479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02045"/>
    <dbReference type="EnsemblBacteria" id="AQP43741">
        <property type="protein sequence ID" value="AQP43741"/>
        <property type="gene ID" value="RPIT_02045"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY22479">
        <property type="protein sequence ID" value="SDY22479"/>
        <property type="gene ID" value="SAMN05428934_1016"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02045"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY22479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="142" mass="15670" checksum="CB11D29A0DDBFE39" modified="2017-04-12" version="1">MELIAWVALRDDADRVLLARRSGTSLADGLWNLPGGHIEDAEPAPVAAAREAGEEVCARLSPDDLVHVGLQRFDVPYTLGRAQGFNFFFEARRWSGELAPGEATSELAWFALDDLPADILPWLPAALQTHLVERRFYVETVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCI6</accession>
    <name>A0A1Q2CCI6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-amylase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Alpha-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02515</name>
        <name evidence="3" type="ORF">SAMN05428934_101102</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY25305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02515"/>
    <dbReference type="EnsemblBacteria" id="AQP43828">
        <property type="protein sequence ID" value="AQP43828"/>
        <property type="gene ID" value="RPIT_02515"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY25305">
        <property type="protein sequence ID" value="SDY25305"/>
        <property type="gene ID" value="SAMN05428934_101102"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02515"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="1">
        <location>
            <begin position="26"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY25305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="557" mass="61808" checksum="A7906E4342CB992E" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCK4</accession>
    <name>A0A1Q2CCK4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_02225</name>
        <name evidence="2" type="ORF">SAMN05428934_10144</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY23632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43775">
        <property type="protein sequence ID" value="AQP43775"/>
        <property type="gene ID" value="RPIT_02225"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY23632">
        <property type="protein sequence ID" value="SDY23632"/>
        <property type="gene ID" value="SAMN05428934_10144"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02225"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY23632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="188" mass="21531" checksum="D692C07C3EFC811D" modified="2017-04-12" version="1">MTHLLEPFPEPSERMLAALVDLAILARGGDAAEAIMATGEILPRLWDITSIADPDLRLDTWQWLDAFVIWLNTQHAWYSADHTPACWPEHPGLVRELGTLAAMRYQAGEATSPMALEEWHRYTLPGYLDRTRDQRRACDEKHQPWPGRAAHTRHADGAARRRHLFDEDVDRTPDAEDTLALWRLPVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCN1</accession>
    <name>A0A1Q2CCN1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_02735</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02735"/>
    <dbReference type="EnsemblBacteria" id="AQP43864">
        <property type="protein sequence ID" value="AQP43864"/>
        <property type="gene ID" value="RPIT_02735"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02735"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04434">
        <property type="entry name" value="SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="3">
        <location>
            <begin position="59"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="434"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="453" mass="49170" checksum="BEAA2881D347D0AF" modified="2017-04-12" version="1">MTDIPTWARTLTDGDLLRAFGAATLVRGRQYAAMNRVTSVSTTADGARATVRGNAMRTYETTLWRTHDGTPHSYCSCPVGRNCKHAVALLVTMRDSTAGADWRRALSRFAPSAAPTGRTPLALSVDQTVEGFTLRPLRPGNREPWIRSGASWDDVRTSPVVFHAEHRTALLALLETRQADRFGGATGGGTFALDRMRVDGWRHLADAVRAGVELIPGHDLGGRVLPPVRLAEHPVTAVIRVDETNDGARVLPLLEVDGEELPPSTRSLLGYPAHGVALRLDDCLLLGPLRVALGEAEHALFGTGEVVVPESDLPVFASAFLPNLSRRLSVHVADGIDLPTVEPVRALARITFDALHATVSWGYRYRVGAEVHDVGLIPTNEDPPVRQPHEEQLLAHSLRDGPWGESLATVRLSGRQLIDFVSSGLPALERREDVALEVSGTPPSSGRRTRRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCR2</accession>
    <name>A0A1Q2CCR2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0234 protein RPIT_02770</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02770</name>
        <name evidence="3" type="ORF">SAMN05428934_101154</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0234 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY26865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02770"/>
    <dbReference type="EnsemblBacteria" id="AQP43870">
        <property type="protein sequence ID" value="AQP43870"/>
        <property type="gene ID" value="RPIT_02770"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY26865">
        <property type="protein sequence ID" value="SDY26865"/>
        <property type="gene ID" value="SAMN05428934_101154"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02770"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11740">
        <property type="entry name" value="YajQ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00632">
        <property type="entry name" value="UPF0234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007551">
        <property type="entry name" value="DUF520"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035571">
        <property type="entry name" value="UPF0234-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035570">
        <property type="entry name" value="UPF0234_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036183">
        <property type="entry name" value="YajQ-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30476">
        <property type="entry name" value="PTHR30476"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04461">
        <property type="entry name" value="DUF520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89963">
        <property type="entry name" value="SSF89963"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY26865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="163" mass="18213" checksum="54F88F07CDCDF8B5" modified="2017-04-12" version="1">MAADSSFDVVSKVDRQEVDNALNQAAKEVSQRFDFKGTDAKIAWSGENIDMEAVSEERVKAVLDVFQSKLARRGVSLKALDAGDPRQSGKLWKITASMKQGIKQEDAKKISKLLRDEGPKGVKCQIQGDELRVSSKSRDDLQAVQALIKEQDYDFAVQYVNYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCT9</accession>
    <name>A0A1Q2CCT9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplB</name>
        <name evidence="7" type="ORF">RPIT_03055</name>
        <name evidence="8" type="ORF">SAMN05428934_101212</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY28626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03055"/>
    <dbReference type="EnsemblBacteria" id="AQP43917">
        <property type="protein sequence ID" value="AQP43917"/>
        <property type="gene ID" value="RPIT_03055"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY28626">
        <property type="protein sequence ID" value="SDY28626"/>
        <property type="gene ID" value="SAMN05428934_101212"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03055"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01320_B">
        <property type="entry name" value="Ribosomal_L2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Rbsml_prot_L2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005880">
        <property type="entry name" value="Ribosomal_L2_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_L2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022671">
        <property type="entry name" value="Ribosomal_L2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_L2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="PTHR13691"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01171">
        <property type="entry name" value="rplB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L2_C" evidence="6">
        <location>
            <begin position="125"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="224"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY28626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="278" mass="30256" checksum="17F1C863D5FCE968" modified="2017-04-12" version="1">MGIRKYKPTTPGRRGSSVADFVELTRSTPEKSLLAPKPKTGGRNNTGRITTRHIGGGHKQAYRIIDFKRYDKDGVPAKVAHIEYDPNRTARIALLHYLDGEKRYIIAPNGLTQGTTVTAGEGSDIKPGNNLELRNIPVGTTVHAVEMRPGGGAKLGRSAGAAIQLVAREGKYATLRMPSGEMRMVDVRCRATVGAVGNAEQSNINWGKAGRKRWKGVRPTVRGVVMNPVDHPHGGGEGRTSGGRHPVSPWGKPEGRTRDKNKASNRLIVRRRKTGKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCU3</accession>
    <name>A0A1Q2CCU3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplD</name>
        <name evidence="7" type="ORF">RPIT_03045</name>
        <name evidence="8" type="ORF">SAMN05428934_101210</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Forms part of the polypeptide exit tunnel.</text>
    </comment>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY28564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03045"/>
    <dbReference type="EnsemblBacteria" id="AQP43916">
        <property type="protein sequence ID" value="AQP43916"/>
        <property type="gene ID" value="RPIT_03045"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY28564">
        <property type="protein sequence ID" value="SDY28564"/>
        <property type="gene ID" value="SAMN05428934_101210"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03045"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01328_B">
        <property type="entry name" value="Ribosomal_L4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_L4/L1e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_L4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4/L1e"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="PTHR10746"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="SSF52166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03953">
        <property type="entry name" value="rplD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="51"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="222"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="227"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY28564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="250" mass="26245" checksum="EA0FAB0F841586AA" modified="2017-04-12" version="1">MSDLTVDVVDAKGKKAGTADLPAELFDAQTNIPLIHQVVVAQLAAARQGTHDTKTRAEVRGGGAKPWRQKGTGRARHGSRRSPIWTGGGVVHGPTPRDYSQRTPKKMIAAALRGALSDRARDGQVYVISEVVAGDKPSTKAALAALTAVAGDVSKVLLVLDRFEDVAWLSVRNSATVHALAVDQLNTYDVLVNDKVVFTSAALAAFVAGPAGGRNVAVEADAEAEPVAETDEKPAKAPKAKAKKTEETDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCU4</accession>
    <name>A0A1Q2CCU4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADH dehydrogenase subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02740</name>
        <name evidence="3" type="ORF">SAMN05428934_101148</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY26695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02740"/>
    <dbReference type="EnsemblBacteria" id="AQP43865">
        <property type="protein sequence ID" value="AQP43865"/>
        <property type="gene ID" value="RPIT_02740"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY26695">
        <property type="protein sequence ID" value="SDY26695"/>
        <property type="gene ID" value="SAMN05428934_101148"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02740"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_q6" evidence="1">
        <location>
            <begin position="41"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY26695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="134" mass="13766" checksum="04D561B2AFAAF9FD" modified="2017-04-12" version="1">MHATDWFDDGSVFVVDVPLACCALETQAAAQGRRAVDLEQLPAGAVVVVTLSGTLTTAAVPAVRHALDQLPADPTVVAFGACACVGGPYWDSYSVVAGGGQIVDVDHFIAGCPPPPDALHSYLEEVRRAGHVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCU9</accession>
    <name>A0A1Q2CCU9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Superfamily II DNA or RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03015</name>
        <name evidence="3" type="ORF">SAMN05428934_101204</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY28374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03015"/>
    <dbReference type="EnsemblBacteria" id="AQP43910">
        <property type="protein sequence ID" value="AQP43910"/>
        <property type="gene ID" value="RPIT_03015"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY28374">
        <property type="protein sequence ID" value="SDY28374"/>
        <property type="gene ID" value="SAMN05428934_101204"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03015"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="35"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY28374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="582" mass="64095" checksum="2EA553CCB02E9145" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCW2</accession>
    <name>A0A1Q2CCW2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyrrolidone-carboxylate peptidase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">5-oxoprolyl-peptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Pyroglutamyl-peptidase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_02870</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02870"/>
    <dbReference type="EnsemblBacteria" id="AQP43885">
        <property type="protein sequence ID" value="AQP43885"/>
        <property type="gene ID" value="RPIT_02870"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02870"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016920">
        <property type="term" value="F:pyroglutamyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00501">
        <property type="entry name" value="Peptidase_C15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000816">
        <property type="entry name" value="Peptidase_C15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016125">
        <property type="entry name" value="Peptidase_C15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036440">
        <property type="entry name" value="Peptidase_C15-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23402">
        <property type="entry name" value="PTHR23402"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01470">
        <property type="entry name" value="Peptidase_C15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015592">
        <property type="entry name" value="Prld-crbxl_pptds"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00706">
        <property type="entry name" value="PYROGLUPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53182">
        <property type="entry name" value="SSF53182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP43885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="209" mass="21746" checksum="92BCA1B9512F29BE" modified="2017-04-12" version="1">MKILLTAFEPFGGDTVNASLDVARAVRDLWAGPGELVTATLSVSFERAPRELLTAIEEQRPDAVVCLGEAGGRDVVTPERWAGAVADARIPDNDGSQPRMLALDDGPDRIGSRLDTDALVVALVRAGTPARASDDAGRFVCNAVYRAVLRHFEGPATFIHVPAIRPDHTTALVGAETDEGGSTRRATISTSVVAAGIAAALAGLQIAPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCX6</accession>
    <name>A0A1Q2CCX6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_03210</name>
        <name evidence="7" type="ORF">SAMN05428934_101243</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43947">
        <property type="protein sequence ID" value="AQP43947"/>
        <property type="gene ID" value="RPIT_03210"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29610">
        <property type="protein sequence ID" value="SDY29610"/>
        <property type="gene ID" value="SAMN05428934_101243"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03210"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007343">
        <property type="entry name" value="Uncharacterised_pept_Zn_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04228">
        <property type="entry name" value="Zn_peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544434" evidence="5">
        <location>
            <begin position="40"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY29610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="292" mass="31120" checksum="7C287AF936D6B5DE" modified="2017-04-12" version="1">MSPGMRLGAAVLGVTVAAALVVVAAQLLRPPIAADRTSAAPSPTATADPAAGALQWQLPEQEWPALPAADPQSPLYEAQATALDAVEPAALVGCPEPGVVADEAAWRSAVTAQWECLHLAWTPHLVSLGWSTEPPELHFFDGLGTASECGYLEAPAFYCSTGGGSAHFGSRHLRMAGEWDLSINEMVNHEYGHHLQKLAGITDVKMGLKSSDEVERRVELQATCWSGAMTYRNESVGFDAADFASWTARLETMLVDGVHGSRDSLRYWGMRGLYAETMGDCNTWVVAAQAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCY1</accession>
    <name>A0A1Q2CCY1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase A</fullName>
            <ecNumber evidence="4">5.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(38-40) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">truA</name>
        <name evidence="9" type="ORF">RPIT_03425</name>
        <name evidence="10" type="ORF">SAMN05428934_101285</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 7">
            <text>uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:22376"/>
            <dbReference type="Rhea" id="RHEA-COMP:10085"/>
            <dbReference type="Rhea" id="RHEA-COMP:10087"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.12" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03425"/>
    <dbReference type="EnsemblBacteria" id="AQP43983">
        <property type="protein sequence ID" value="AQP43983"/>
        <property type="gene ID" value="RPIT_03425"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30904">
        <property type="protein sequence ID" value="SDY30904"/>
        <property type="gene ID" value="SAMN05428934_101285"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03425"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02570">
        <property type="entry name" value="PseudoU_synth_EcTruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PTHR11142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001430">
        <property type="entry name" value="tRNA_psdUrid_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00071">
        <property type="entry name" value="hisT_truA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="152"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4 5">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP43983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY30904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="281" mass="30788" checksum="7B31AB3954A3BC4F" modified="2017-04-12" version="1">MRLRIDLAYDGTDFRGWAVQPGLRTVQGELEGWIGQVLRLTEPPTLVVAGRTDAGVHARGQVCHVDLPDAAGPDPDVTAATLHRRLTRVLGSDVVVQKVSPAPAGFDARFSALWRRYCYRISDDSAPADPLMRGHVARVRYLLDLDTLNASAATLVGLRDFAAFCRPREGATTIRELRELRASRRGDGVIEVHLLADAFCHSMVRSLVGALTAVAAGRRSQSWLELAATSPSRHNEINVMPAHGLTLEEVGYPPDDELASRADVARAVRTLDPDRFQQEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD22</accession>
    <name>A0A1Q2CD22_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44023">
        <property type="protein sequence ID" value="AQP44023"/>
        <property type="gene ID" value="RPIT_03675"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03675"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="145" mass="15988" checksum="468CC3B95F04B935" modified="2017-04-12" version="1">MLRGAFIAVGAVLIESFSWFRYPLPLAVIASILTLSVVTSLRVTRGTVHVVSEIKPILLPAARCRRRLGCLAPRSQSERNADQSERQGPGPDGDARRDHWKRKGPAERRRDPDVLHTFPDLPGEPASSWPSVISRCVGRWGRSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDA0</accession>
    <name>A0A1Q2CDA0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminomethyltransferase</fullName>
            <ecNumber evidence="3">2.1.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Glycine cleavage system T protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gcvT</name>
        <name evidence="9" type="ORF">RPIT_04140</name>
        <name evidence="10" type="ORF">SAMN05428934_101432</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6S)-5,6,7,8-tetrahydrofolate + (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[protein] = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16945"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10492"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="2.1.2.10"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GcvT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.10" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY35056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04140"/>
    <dbReference type="EnsemblBacteria" id="AQP44102">
        <property type="protein sequence ID" value="AQP44102"/>
        <property type="gene ID" value="RPIT_04140"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY35056">
        <property type="protein sequence ID" value="SDY35056"/>
        <property type="gene ID" value="SAMN05428934_101432"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04140"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004047">
        <property type="term" value="F:aminomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006546">
        <property type="term" value="P:glycine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006223">
        <property type="entry name" value="GCS_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GCST/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GCV_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCV_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="PTHR43757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="SSF101790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00528">
        <property type="entry name" value="gcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GCV_T" evidence="7">
        <location>
            <begin position="6"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="GCV_T_C" evidence="8">
        <location>
            <begin position="284"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY35056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="367" mass="39049" checksum="167F096A5B89B19E" modified="2017-04-12" version="1">MQTTALHALHQELGGKLVDFAGWELPVQFSGGIAEHHHTRTAASLFDVSHMGQVLVRPTSGQVADAATALETLIPASIVGLAPWRQRYGLFTSADGGVLDDLMIANHSTHFFLVVNAARTEHDLAHLRSLGEVEVEHVADRSLLALQGPRAGGALTQLIPEATGLVFMDSVKLSWDGTEVWVSRSGYTGEDGFEISLPNERAEEFARRLLDIDGVAPAGLGARDSLRLEAGMPLYGHDLTEDINPVEAGLAFAIPKVRRSGGSRAGGFPGADVILPLLDTGTPRERVGLRAEGRAPVRDRAPLFASAESDEQIAVVTSGGFGPSVGGPIAMAMLPRGTAGTVYAEVRGKRLPLSVTDLPFIPHQYKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDA8</accession>
    <name>A0A1Q2CDA8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phospho-N-acetylmuramoyl-pentapeptide-transferase</fullName>
            <ecNumber evidence="7">2.7.8.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-pentapeptide phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mraY</name>
        <name evidence="8" type="ORF">RPIT_04015</name>
        <name evidence="9" type="ORF">SAMN05428934_101406</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine = di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP</text>
            <dbReference type="Rhea" id="RHEA:28386"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="EC" id="2.7.8.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyltransferase 4 family. MraY subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.13" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY34256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04015"/>
    <dbReference type="EnsemblBacteria" id="AQP44081">
        <property type="protein sequence ID" value="AQP44081"/>
        <property type="gene ID" value="RPIT_04015"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY34256">
        <property type="protein sequence ID" value="SDY34256"/>
        <property type="gene ID" value="SAMN05428934_101406"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04015"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051992">
        <property type="term" value="F:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06852">
        <property type="entry name" value="GT_MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00038">
        <property type="entry name" value="MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003524">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018480">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10555">
        <property type="entry name" value="MraY_sig1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00445">
        <property type="entry name" value="mraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01347">
        <property type="entry name" value="MRAY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01348">
        <property type="entry name" value="MRAY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY34256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="356" mass="38587" checksum="058D6F5FA834C630" modified="2017-04-12" version="1">MIMILLAGGLSLLFAMLATPLLINFLTRRQYGQFIREDGPTAHYVKRGTPTMGGLVIVGAAVLAYFVAHLLRWQAPSLSALLVLGLAIGMGTLGFLDDWAKISKERSLGLTPRGKLIGQFLIGAAFALLALNFPNDRGLTPASPAVSFLRDINWLHLPLFLAVLFIVFLIMSWSNAVNLTDGLDGLAAGSATLVFAAYTLVSIWQFNQWCSRASTAGPRCYVVRDPHDLAVVAIAFAGACFGFLWWNAKPAKIFMGDTGSMAIGATLAGLSVLTRTELLLVVLGLLFVIEVGSVALQVGYFKATKGKRIFKMSPIHHHFELLGWQEVTVVIRFWIICGLCVALGVGIFYAEWVVGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDB2</accession>
    <name>A0A1Q2CDB2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative gluconeogenesis factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_04200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Required for morphogenesis under gluconeogenic growth conditions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the gluconeogenesis factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04200"/>
    <dbReference type="EnsemblBacteria" id="AQP44113">
        <property type="protein sequence ID" value="AQP44113"/>
        <property type="gene ID" value="RPIT_04200"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04200"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043743">
        <property type="term" value="F:LPPG:FO 2-phospho-L-lactate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00973">
        <property type="entry name" value="Gluconeogen_factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002882">
        <property type="entry name" value="CofD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038136">
        <property type="entry name" value="CofD-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010119">
        <property type="entry name" value="Gluconeogen_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30135">
        <property type="entry name" value="PTHR30135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01933">
        <property type="entry name" value="CofD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142338">
        <property type="entry name" value="SSF142338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01826">
        <property type="entry name" value="CofD_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="315" mass="33314" checksum="287E7CBE4142457B" modified="2017-04-12" version="1">MMASRLPRVVALGGGHGLAASLTALRRITDRLTAVVTVADDGGSSGRLRREFGCLPPGDLRMALAALCSDDHEGRTWADVLQARFRGDGPLAGHAIGNLLIAGLWQHFDDEVEGLDMVGSLLRTRGRVLPMSSVPLEIEADVLGLDPLEPDEVCTLSGQATVATSRATVQAVRLVPERPPARPEAVSAIREADSIVLGPGSWFTSVIPHLLVPDLAAAILGTRAQRVLVLNIAPAEETDGFTPSRHIELLAEHAPGLRLDVVIADERFAASDPHLEKFVTSLGGRVVTADVAARDGSPTHDPNRLAAVLSEVIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDE7</accession>
    <name>A0A1Q2CDE7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04225</name>
        <name evidence="3" type="ORF">SAMN05428934_101449</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY35618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04225"/>
    <dbReference type="EnsemblBacteria" id="AQP44117">
        <property type="protein sequence ID" value="AQP44117"/>
        <property type="gene ID" value="RPIT_04225"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY35618">
        <property type="protein sequence ID" value="SDY35618"/>
        <property type="gene ID" value="SAMN05428934_101449"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04225"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY35618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="450" mass="49294" checksum="A3E871582E95587F" modified="2017-04-12" version="1">MLLAELAEQYVLPRGAEETHGALVSDALIEEVHPFGGPGAPLISEYAAPEVAALLGISRRKATILIEGAVHLKWQLPGLYERMSRLLVEADRAVQASYSVSGLPPELARIVIERWLPIQERYSWTGAFNKLSELIAEVDPHRAEEEAQALQQRQVTVTTGKGNLGDAAVGYIEATVDVVDAKLFDAALTQIAGLLQSVHGDDSPMAIRRAKAFGVLSRPAYALALIQRGAQAESDPSPSLPIEQEADDRQPRHSDSDRLLPGSCTGHTCGTITIPIEKLLPKVGIEVVIDADAVGADAVARIDEATVIATTTLAELLGGKSVQLRPVIDLPRVPSEHQYRPSLAMRRAVLRRWRHEAFPFSHRRTGGLDLDHVQPYRSDGTPGQTSQRNLIPLGRGNHRAKTARLWMVRIDNLGRALWESPLGYRYVVTPYGTEPVLPLRLYGRDRQRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDH5</accession>
    <name>A0A1Q2CDH5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable dual-specificity RNA methyltransferase RlmN</fullName>
            <ecNumber evidence="11">2.1.1.192</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">23S rRNA (adenine(2503)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">23S rRNA m2A2503 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Ribosomal RNA large subunit methyltransferase N</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">tRNA (adenine(37)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">tRNA m2A37 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rlmN</name>
        <name evidence="13" type="ORF">RPIT_04520</name>
        <name evidence="14" type="ORF">SAMN05428934_101510</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(2503) in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42916"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10152"/>
            <dbReference type="Rhea" id="RHEA-COMP:10282"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>adenosine(37) in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(37) in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43332"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10485"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="11">Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the radical SAM superfamily. RlmN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.192" evidence="11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04520"/>
    <dbReference type="EnsemblBacteria" id="AQP44168">
        <property type="protein sequence ID" value="AQP44168"/>
        <property type="gene ID" value="RPIT_04520"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37142">
        <property type="protein sequence ID" value="SDY37142"/>
        <property type="gene ID" value="SAMN05428934_101510"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04520"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070040">
        <property type="term" value="F:rRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002935">
        <property type="term" value="F:tRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01849">
        <property type="entry name" value="RNA_methyltr_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040072">
        <property type="entry name" value="Methyltransferase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027492">
        <property type="entry name" value="RNA_MTrfase_RlmN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004383">
        <property type="entry name" value="rRNA_lsu_MTrfase_RlmN/Cfr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544">
        <property type="entry name" value="PTHR30544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006004">
        <property type="entry name" value="CHP00048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00275">
        <property type="entry name" value="adenosine_C2_methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00048">
        <property type="entry name" value="rRNA_mod_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 11" id="KW-0408">Iron</keyword>
    <keyword evidence="10 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="7 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 11 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Radical SAM core" evidence="12">
        <location>
            <begin position="115"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="11">
        <location>
            <begin position="184"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="11">
        <location>
            <begin position="241"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <feature type="active site" description="S-methylcysteine intermediate" evidence="11">
        <location>
            <position position="364"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP44168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY37142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="374" mass="41182" checksum="E48FBDA565E08DC5" modified="2017-04-12" version="1">MSGSPLPLVFDAPARGKAPKHWLDLTPDERRETAEKLGLPRYRADQISRHVFDRLEDDATHFTDLPAAIREDLAEQIFPSLLERVTTRTADKGATVKTLWKLHDGSLLESVLMRYPNRSTLCISSQAGCGMACPFCATGQGGLKRNLSQAEITIQALAANQMLTRGEVPGTTGRLNNIVFMGMGEPLANYRAVLGSIRTLLAPSPDGFGMSARGITVSTVGLVPQIRKLTEEELPLTLAVSLHAPDDELRDEIVPVNNRWKVAEVVDAAWDYARTTKRRVSIEYAMMRDINDQVSRAHLLADILKRRGDWGWVHVNLIPLNPTPGSKWTASRKEDERAFVATLERRGVPVTLRDTRGSEIDGACGQLAATVEAS</sequence>
</entry>
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    <name>A0A1Q2CDM7_9ACTN</name>
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        <submittedName>
            <fullName evidence="4">Phosphoglycerol transferase MdoB</fullName>
        </submittedName>
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        <name evidence="3" type="ORF">RPIT_04585</name>
        <name evidence="4" type="ORF">SAMN05428934_101523</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="SAMN05428934_101523"/>
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    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:sulfuric ester hydrolase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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            <end position="40"/>
        </location>
    </feature>
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        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <end position="163"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="2">
        <location>
            <begin position="246"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY37456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="623" mass="69887" checksum="2AB8375C76FB1AB3" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDP1</accession>
    <name>A0A1Q2CDP1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Porphobilinogen deaminase</fullName>
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            <ecNumber evidence="6">2.5.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
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            <shortName evidence="6">HMBS</shortName>
        </alternativeName>
        <alternativeName>
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        </alternativeName>
    </protein>
    <gene>
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        <name evidence="11" type="ORF">SAMN05428934_101555</name>
    </gene>
    <organism evidence="10 12">
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>H2O + 4 porphobilinogen = hydroxymethylbilane + 4 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="EC" id="2.5.1.61"/>
        </reaction>
    </comment>
    <comment type="cofactor">
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            <dbReference type="ChEBI" id="CHEBI:60342"/>
        </cofactor>
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    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="6">The porphobilinogen subunits are added to the dipyrromethane group.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the HMBS family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP44207">
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        <property type="gene ID" value="RPIT_04730"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY38247">
        <property type="protein sequence ID" value="SDY38247"/>
        <property type="gene ID" value="SAMN05428934_101555"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04730"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004418">
        <property type="term" value="F:hydroxymethylbilane synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018160">
        <property type="term" value="P:peptidyl-pyrromethane cofactor linkage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000860">
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    </dbReference>
    <dbReference type="InterPro" id="IPR022419">
        <property type="entry name" value="Porphobilin_deaminase_cofac_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022417">
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    </dbReference>
    <dbReference type="InterPro" id="IPR022418">
        <property type="entry name" value="Porphobilinogen_deaminase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036803">
        <property type="entry name" value="Porphobilinogen_deaminase_C_sf"/>
    </dbReference>
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        <property type="entry name" value="PTHR11557"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01379">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PORPHBDMNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54782">
        <property type="entry name" value="SSF54782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="SSF69618"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="hemC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00533">
        <property type="entry name" value="PORPHOBILINOGEN_DEAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Porphobil_deam" evidence="7">
        <location>
            <begin position="3"/>
            <end position="203"/>
        </location>
    </feature>
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        <location>
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            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="HEM4" evidence="8">
        <location>
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            <end position="534"/>
        </location>
    </feature>
    <feature type="modified residue" description="S-(dipyrrolylmethanemethyl)cysteine" evidence="6">
        <location>
            <position position="233"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY38247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="544" mass="56006" checksum="2D3C30335870838E" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDY3</accession>
    <name>A0A1Q2CDY3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sporulation and spore germination</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_05340</name>
        <name evidence="6" type="ORF">SAMN05428934_10315</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY65408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05340"/>
    <dbReference type="EnsemblBacteria" id="AQP44307">
        <property type="protein sequence ID" value="AQP44307"/>
        <property type="gene ID" value="RPIT_05340"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY65408">
        <property type="protein sequence ID" value="SDY65408"/>
        <property type="gene ID" value="SAMN05428934_10315"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05340"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019606">
        <property type="entry name" value="GerMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018910">
        <property type="entry name" value="Lipoprotein_LpqB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10646">
        <property type="entry name" value="Germane"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Gmad1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00909">
        <property type="entry name" value="Germane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-0564">Palmitate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544447" evidence="3">
        <location>
            <begin position="29"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="domain" description="Germane" evidence="4">
        <location>
            <begin position="189"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY65408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="564" mass="59095" checksum="BDC1570E661D42D2" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE29</accession>
    <name>A0A1Q2CE29_9ACTN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">SAMN05428934_10373</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
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    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP44358">
        <property type="protein sequence ID" value="AQP44358"/>
        <property type="gene ID" value="RPIT_05630"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY67027"/>
        <property type="gene ID" value="SAMN05428934_10373"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021555">
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    </dbReference>
    <dbReference type="Pfam" id="PF11452">
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY67027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="194" mass="21232" checksum="376C1B146C171763" modified="2017-04-12" version="1">MPANVTNIAPEPFARALRELSGMRWRRHFTVDEIGSPQRIAPHSVAIEAELSLDDTEDPLATGRLILLHDPLGNESWAGTFRLVTYVRAEVEMDIVTDPLLPEVAWSWFTEALETHGCVASALAGTVTASYGKGFGEMTDADRAEVELRSSWTPTLDQDHPLTSHLAAWQDLVGQVAGQPPYPVGVAHLPTGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE42</accession>
    <name>A0A1Q2CE42_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">KDO2-lipid IV(A) lauroyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_05700</name>
        <name evidence="7" type="ORF">SAMN05428934_10387</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05700"/>
    <dbReference type="EnsemblBacteria" id="AQP44367">
        <property type="protein sequence ID" value="AQP44367"/>
        <property type="gene ID" value="RPIT_05700"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67318">
        <property type="protein sequence ID" value="SDY67318"/>
        <property type="gene ID" value="SAMN05428934_10387"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05700"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd07984">
        <property type="entry name" value="LPLAT_LABLAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004960">
        <property type="entry name" value="LipA_acyltrans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03279">
        <property type="entry name" value="Lip_A_acyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY67318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="274" mass="29987" checksum="32840978F3A974F3" modified="2017-04-12" version="1">MDTVALTWAVGRRIPRRVADLVARIVAPAAALMSLPAVDAWAESVEIATGRAPTPRQRRLLLQAWIRNNLWSLSLARWSTDEVLATVAVDDVDVARLRDSLAGPGLVAALPHMGSWDFAGAWASRMGMSVVSVAERLPRGLYERFSEARRGMGIDIYPVDQPDVVRLLTDDVHAGRLVCLLADRDLSSRGVLVPWPGSGRDVAVARGPAHVALRSGADLRVVTTHFDGPRLRIEVSEPVEGESVEELMAGVARVFADAVSRHPESWLMLRRVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE87</accession>
    <name>A0A1Q2CE87_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">16S rRNA (Cytosine967-C5)-methyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">rRNA cytosine-C5-methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_06135</name>
        <name evidence="8" type="ORF">SAMN05428934_103172</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY69502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06135"/>
    <dbReference type="EnsemblBacteria" id="AQP44442">
        <property type="protein sequence ID" value="AQP44442"/>
        <property type="gene ID" value="RPIT_06135"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY69502">
        <property type="protein sequence ID" value="SDY69502"/>
        <property type="gene ID" value="SAMN05428934_103172"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06135"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001510">
        <property type="term" value="P:RNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB/NOP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035926">
        <property type="entry name" value="NusB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006027">
        <property type="entry name" value="NusB_RsmB_TIM44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="PTHR22807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01029">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48013">
        <property type="entry name" value="SSF48013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM_MT_RSMB_NOP" evidence="6">
        <location>
            <begin position="144"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="253"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="373"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY69502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="434" mass="46082" checksum="EF24AB23A08A2BFD" modified="2017-04-12" version="1">MNARRTAFDVLRQVTAEDSYANLALAKRLATAGLDARDAGLVTELVAGTCRSMGTYDAILEEAAGRKLSSLQPAVVDLLRLGAHQILGMRLKKYAAVGATVDLARATVGQRVTGVVNAVLRKVAARDLDGWLDLLAEGEDRIGALAVRGRHPHWIVEAYAEVLPADELEAALTANNVSPQPTLVVRPGLADLGDLDGATPTRFSPFGATVAGSPADQEAVRQGRVGVQDEGSQLVAWALARTPAPEGPWLDTCAGPGGKAALLTGLAREAGTWLLASEAQEHRARLVRQALAGYPDGAAVIAADGTAPAWDRAFARVMVDVPCSGLGALRRRPESRWRRSPADVAALGQLQRDLLRRAIDSTVDGGVVAYVTCSPHRAETVDVVDDVLAERPQARRLHAPDALPDVPDCSLGDDVQLWTHRHGTDAMYMSLIRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEB3</accession>
    <name>A0A1Q2CEB3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">DNA-directed RNA polymerase subunit omega</fullName>
            <shortName evidence="11">RNAP omega subunit</shortName>
            <ecNumber evidence="2 11">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">RNA polymerase omega subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10 11">Transcriptase subunit omega</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rpoZ</name>
        <name evidence="12" type="ORF">RPIT_06155</name>
        <name evidence="13" type="ORF">SAMN05428934_103176</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 11">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9 11">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the RNA polymerase subunit omega family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2 11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY69598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06155"/>
    <dbReference type="EnsemblBacteria" id="AQP44446">
        <property type="protein sequence ID" value="AQP44446"/>
        <property type="gene ID" value="RPIT_06155"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY69598">
        <property type="protein sequence ID" value="SDY69598"/>
        <property type="gene ID" value="SAMN05428934_103176"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06155"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00366">
        <property type="entry name" value="RNApol_bact_RpoZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003716">
        <property type="entry name" value="DNA-dir_RNA_pol_omega"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006110">
        <property type="entry name" value="Pol_omega/Rpo6/RPB6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036161">
        <property type="entry name" value="RPB6/omega-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34476">
        <property type="entry name" value="PTHR34476"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01192">
        <property type="entry name" value="RNA_pol_Rpb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01409">
        <property type="entry name" value="RNA_pol_Rpb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63562">
        <property type="entry name" value="SSF63562"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00690">
        <property type="entry name" value="rpoZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11 12" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP44446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY69598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="118" mass="12880" checksum="BB83E650A9605F8C" modified="2017-04-12" version="1">MSIHPEGITNPPIDSLLENIDSKYRLVLFAAKRARQINAYYSQLGEGLLENVGPMVAAAPEEKPLSIALREMSEGLLQYTEIDPAVEEAQRTADIDPAFTFVDPFAESTDDAEADPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEB4</accession>
    <name>A0A1Q2CEB4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">Methionyl-tRNA formyltransferase</fullName>
            <ecNumber evidence="4 8">2.1.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fmt</name>
        <name evidence="11" type="ORF">RPIT_06140</name>
        <name evidence="12" type="ORF">SAMN05428934_103173</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(6S)-10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = (6S)-5,6,7,8-tetrahydrofolate + H(+) + N-formyl-L-methionyl-tRNA(fMet)</text>
            <dbReference type="Rhea" id="RHEA:24380"/>
            <dbReference type="Rhea" id="RHEA-COMP:9952"/>
            <dbReference type="Rhea" id="RHEA-COMP:9953"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:78844"/>
            <dbReference type="EC" id="2.1.2.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the Fmt family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.9" evidence="4 8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY69524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06140"/>
    <dbReference type="EnsemblBacteria" id="AQP44443">
        <property type="protein sequence ID" value="AQP44443"/>
        <property type="gene ID" value="RPIT_06140"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY69524">
        <property type="protein sequence ID" value="SDY69524"/>
        <property type="gene ID" value="SAMN05428934_103173"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06140"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004479">
        <property type="term" value="F:methionyl-tRNA formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08646">
        <property type="entry name" value="FMT_core_Met-tRNA-FMT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08704">
        <property type="entry name" value="Met_tRNA_FMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00182">
        <property type="entry name" value="Formyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005794">
        <property type="entry name" value="Fmt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005793">
        <property type="entry name" value="Formyl_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044135">
        <property type="entry name" value="Met-tRNA-FMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041711">
        <property type="entry name" value="Met-tRNA-FMT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02911">
        <property type="entry name" value="Formyl_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="SSF50486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00460">
        <property type="entry name" value="fmt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="9">
        <location>
            <begin position="2"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Formyl_trans_C" evidence="10">
        <location>
            <begin position="201"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Tetrahydrofolate (THF) binding" evidence="8">
        <location>
            <begin position="109"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY69524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="303" mass="32530" checksum="D5AAF0267EBE4ADE" modified="2017-04-12" version="1">MKLVFAGTPDVAVPSLEALVESHHEVLAVITRPDAPAGRGRRLTPSPVAARAEELGLHVLKPAHPRDEDFQAQLRALAPDACAVVAYGALLPQSALDIPRHGWINLHFSLLPRWRGAAPVQRAIMAGDPAIGTATFRIVKELDAGDVYLSQSMATPEETAGELFGRLARSGATQLVQTMDLVEAGQTPTPQREDGITVAPKITVPEARIDWTRGSEELRNHILGCSPDPGAWCELAGERFKIYRARLAEYADLAPGEVAATKRQVFVGTGQGALELLEVQAPGKRRMSAIDWARAGVSGRVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CET8</accession>
    <name>A0A1Q2CET8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Peptide/nickel transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_06850</name>
        <name evidence="9" type="ORF">SAMN05428934_11076</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06850"/>
    <dbReference type="EnsemblBacteria" id="AQP44565">
        <property type="protein sequence ID" value="AQP44565"/>
        <property type="gene ID" value="RPIT_06850"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09620">
        <property type="protein sequence ID" value="SDZ09620"/>
        <property type="gene ID" value="SAMN05428934_11076"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06850"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544448" evidence="6">
        <location>
            <begin position="27"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="238"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="282"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="96"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ09620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="319" mass="34357" checksum="9960F50B6DAD4BF3" modified="2017-04-12" version="1">MVLRRVGVRTAWLLASLLLASLLIFAATNALPGDIAQVMLGTNATPGEAEALRERLGLNRPFLVRYLEWLWAAVRGNFGVSYISGRSVGSLIASRLSVSVWLAGLGMIFAVLLALPIGAYAAMRRRHLDGAVVSALSQVGLAVPAFWAGIWLVIIFAVTLGWFPAGGYVSYFDGVGRWASHLALPVASLAVVQASVISRYVRSAVIEVSHEDYFRTARAVGWSRAGALWRHGLRNIGISLLTVIGLQLATLLVGAIIIEQVFALPGLGSTLLLAVSQRDLGIVQAIVLLMVWAVLLINFLVDVAYQLVDPRLRRGGEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF01</accession>
    <name>A0A1Q2CF01_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mrr_cat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_07365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44650">
        <property type="protein sequence ID" value="AQP44650"/>
        <property type="gene ID" value="RPIT_07365"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07365"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007560">
        <property type="entry name" value="Restrct_endonuc_IV_Mrr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04471">
        <property type="entry name" value="Mrr_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Mrr_cat" evidence="2">
        <location>
            <begin position="147"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="267" mass="29220" checksum="9D27B99C05409F95" modified="2017-04-12" version="1">MFDAVRREIGPQIRPRDARLEREAAQHRNATVLLVMMTLASAGLRVGLVTFRDAEWMPAVGREFPLEALGWAMVALTSVTVLSWVLYLVASWRASRRIRKLRKSLLGAAYEGALQSFGEVGSTTADPAITAVVSEDRFFDDNQGSTAMSPRAAEHLAAYWMRTLGAVDAEVTRFRGDGGVDVTSSRYIAQVKHFSSNVGVAPIRELSGVVRLDGRRGLFFTTAGYSSGAIEFANASGIALFVMDWANGRLMAVNDIARALQRHRLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF06</accession>
    <name>A0A1Q2CF06_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44683">
        <property type="protein sequence ID" value="AQP44683"/>
        <property type="gene ID" value="RPIT_07580"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07580"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="172" mass="19084" checksum="F5510103E677D2CE" modified="2017-04-12" version="1">MLWSIEPEDLEQQAVLCLAIPAFDFLVHELGVGRQSTAVIEHPIFDETLADEELNDLVQRFGALNREMWRRLLGNDERVSFHFARAWFGDHPVSWVASVMVLADVEPEAVVEAALRLGLQRVVELPSLLPSMLDAFHATGMGAHPGVRIVERVARAHSLASRFHAGGWTVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF22</accession>
    <name>A0A1Q2CF22_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Toxin-antitoxin system antitoxin subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07810</name>
        <name evidence="2" type="ORF">SAMN05428934_1132</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44722">
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        <property type="gene ID" value="RPIT_07810"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ16019"/>
        <property type="gene ID" value="SAMN05428934_1132"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07810"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
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        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ16019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="78" mass="8511" checksum="A4AB259A992897DB" modified="2017-04-12" version="1">MSSLTIRQLNEHTHARLRGRAAKHGRSVEAEVRAILDAAVDLPDENILLALHTAISEVGGVELQVPVRDDLPRPVDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF40</accession>
    <name>A0A1Q2CF40_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07880</name>
        <name evidence="3" type="ORF">SAMN05428934_11316</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44734">
        <property type="protein sequence ID" value="AQP44734"/>
        <property type="gene ID" value="RPIT_07880"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16319">
        <property type="protein sequence ID" value="SDZ16319"/>
        <property type="gene ID" value="SAMN05428934_11316"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07880"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ16319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="137" mass="14868" checksum="996E483C6AD38599" modified="2017-04-12" version="1">MDSDIDWGVIAATALVGAGMVGFFVVGILAYAGRWARLRLRMILDPEGHRLAGGLWLSLLALPIAVMVLVESPDRGLGPVHWLALVAMAGLLVAMLSLAFNRPARLTRLLTPHWLLSERERLFGPLRPDGRPKGRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF70</accession>
    <name>A0A1Q2CF70_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acetolactate synthase small subunit</fullName>
            <shortName evidence="8">AHAS</shortName>
            <shortName evidence="8">ALS</shortName>
            <ecNumber evidence="8">2.2.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Acetohydroxy-acid synthase small subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_07965</name>
        <name evidence="11" type="ORF">SAMN05428934_11333</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25249"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="2.2.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 8">Dimer of large and small chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the acetolactate synthase small subunit family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07965"/>
    <dbReference type="EnsemblBacteria" id="AQP44748">
        <property type="protein sequence ID" value="AQP44748"/>
        <property type="gene ID" value="RPIT_07965"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16622">
        <property type="protein sequence ID" value="SDZ16622"/>
        <property type="gene ID" value="SAMN05428934_11333"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07965"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990610">
        <property type="term" value="F:acetolactate synthase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04878">
        <property type="entry name" value="ACT_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004789">
        <property type="entry name" value="Acetalactate_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027271">
        <property type="entry name" value="Acetolactate_synth/TF_NikR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019455">
        <property type="entry name" value="Acetolactate_synth_ssu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039557">
        <property type="entry name" value="AHAS_ACT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30239">
        <property type="entry name" value="PTHR30239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10369">
        <property type="entry name" value="ALS_ss_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00119">
        <property type="entry name" value="acolac_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="9">
        <location>
            <begin position="5"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDZ16622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="167" mass="18026" checksum="2E4A03D9B79CC469" modified="2017-04-12" version="1">MNTHTLSILVSNKPGVLTRIAALFSRRGFNIQSLAVGPTERDQVSRMTVVAQVEDDAALEQIVKQLNKLIEVRKVLELGPSAVLREMMLVKVRADVGTRSQVIDVVSLFRGKAVDVSADTITIEATGSQEKLTALLEMLTPHGVIELVQSGQVALGRGAKVLAEKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF71</accession>
    <name>A0A1Q2CF71_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07735</name>
        <name evidence="3" type="ORF">SAMN05428934_11811</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000018">
        <property type="protein sequence ID" value="SDZ21422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44710">
        <property type="protein sequence ID" value="AQP44710"/>
        <property type="gene ID" value="RPIT_07735"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ21422">
        <property type="protein sequence ID" value="SDZ21422"/>
        <property type="gene ID" value="SAMN05428934_11811"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07735"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021354">
        <property type="entry name" value="DUF2975"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11188">
        <property type="entry name" value="DUF2975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ21422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="202" mass="21063" checksum="003F709DD9E16E72" modified="2017-04-12" version="1">MEATDKLRFDKTDFSVTKLIAAGATALTAILAIGTSLGAWISGEALEVELPASTAIQYDPTVPGVVLTTGSTMMARFENPDAGLLLASMAPSLVLVALMAVATWLLWRVLDSVQADQPFTAATVNRMRALSYVVSIGAIVHQAVVGLVSGHLTSRATGETVLFQVSFDVGFIAIVVGGAMLAALAEAFRRGIRLEADAEGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF94</accession>
    <name>A0A1Q2CF94_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_08245</name>
        <name evidence="8" type="ORF">SAMN05428934_11526</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08245"/>
    <dbReference type="EnsemblBacteria" id="AQP44789">
        <property type="protein sequence ID" value="AQP44789"/>
        <property type="gene ID" value="RPIT_08245"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19535">
        <property type="protein sequence ID" value="SDZ19535"/>
        <property type="gene ID" value="SAMN05428934_11526"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08245"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003012">
        <property type="entry name" value="Tet_transcr_reg_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00400">
        <property type="entry name" value="TETREPRESSOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="6">
        <location>
            <begin position="2"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="5">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ19535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="181" mass="19127" checksum="B8AB1094157F2CD6" modified="2017-04-12" version="1">MALTKQAIVGAALAILDDYGLADLTMRRVADSLGVQAGALYYHVPNKQSLLAAVADHILAERPAVSTPGDPGETLRLWGRGLRSVLLTHRDAAELVASTQVLGLGEVDPCLEGREALIAAGLQQPDATMAALLHFILGHVTGEQTRLQLAQLSVATAPDEAASERDFEWGLGLMIRGICGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFI6</accession>
    <name>A0A1Q2CFI6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="5">3.4.21.92</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Endopeptidase Clp</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">clpP</name>
        <name evidence="8" type="ORF">RPIT_08810</name>
        <name evidence="9" type="ORF">SAMN05428934_10772</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 7">Belongs to the peptidase S14 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08810"/>
    <dbReference type="EnsemblBacteria" id="AQP44879">
        <property type="protein sequence ID" value="AQP44879"/>
        <property type="gene ID" value="RPIT_08810"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97768">
        <property type="protein sequence ID" value="SDY97768"/>
        <property type="gene ID" value="SAMN05428934_10772"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08810"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033135">
        <property type="entry name" value="ClpP_His_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00382">
        <property type="entry name" value="CLP_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY97768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="198" mass="21441" checksum="1023051AECD153A9" modified="2017-04-12" version="1">MAGPGALGLGMNDNVYSALLANRIIFLGSEVKDENANAICAQMLLLNAEDPHKDIYLYINSPGGSVDSGMAIFDTMQWISNDVATVAMGLAASMGQFLLSAGTPGKRFALPHSRIMMHQPSGGLGGTASDIRIQAEQSLHIKRTMARLIAEHTGQTVEQIEADSDRDRWFTAEQALEYGFIDHVYERASQITTEAPNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFJ2</accession>
    <name>A0A1Q2CFJ2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Carbohydrate ABC transporter membrane protein 2, CUT1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_08855</name>
        <name evidence="8" type="ORF">SAMN05428934_10782</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08855"/>
    <dbReference type="EnsemblBacteria" id="AQP44886">
        <property type="protein sequence ID" value="AQP44886"/>
        <property type="gene ID" value="RPIT_08855"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97935">
        <property type="protein sequence ID" value="SDY97935"/>
        <property type="gene ID" value="SAMN05428934_10782"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08855"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="202"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="90"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY97935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="295" mass="33289" checksum="E4128C49AA8D177C" modified="2017-04-12" version="1">MSTATQDPTIRRRPRKAKGSDADTRRTNWWVTAFIAVCSLTVLVPLYLAVVVALKTPDQLTTGTGFEWPTEVRWENFAEAWERTNFPQAITNTGLITVFALVFTLLTNSLVAYALARNMHRRFFKGVYFYLLAALFIPFPIIMLPVAKQTGMLHLDNQVGLIILYTVFGLSLNVFIYTAYIRSIPIELEEAARMDGASTWGVFWRVIFPLLSPMNATVGILTCVWAWNDFILPLVILTDPAARTLPLANYVFQGQFNTDYTVAFASYLMAMAPLMLVYVFSQRWVISGVTRGSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFR2</accession>
    <name>A0A1Q2CFR2_9ACTN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_09330</name>
        <name evidence="2" type="ORF">SAMN05428934_102443</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY60925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44962">
        <property type="protein sequence ID" value="AQP44962"/>
        <property type="gene ID" value="RPIT_09330"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY60925">
        <property type="protein sequence ID" value="SDY60925"/>
        <property type="gene ID" value="SAMN05428934_102443"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09330"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY60925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="170" mass="19156" checksum="E10AA6C769BC4671" modified="2017-04-12" version="1">MFTDVMSAGAFRLRVLMTTHCAYDLTDGGVSERLMRSLMDEPVTLDELLRLGYLDRAVREERGVQIEGYHLSGFEDGQMSRDQRLAEREAARNRMRNVRASRKGSGVRANVRRTSSELIANVRDVVVVPVVVVVEETQWLRSPMTSRQMLHKGLRADETGATCLCQALSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFV9</accession>
    <name>A0A1Q2CFV9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted arabinose efflux permease, MFS family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_09545</name>
        <name evidence="8" type="ORF">SAMN05428934_102397</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY59680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09545"/>
    <dbReference type="EnsemblBacteria" id="AQP44999">
        <property type="protein sequence ID" value="AQP44999"/>
        <property type="gene ID" value="RPIT_09545"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59680">
        <property type="protein sequence ID" value="SDY59680"/>
        <property type="gene ID" value="SAMN05428934_102397"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09545"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="318"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="346"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="392"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="416"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="8"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY59680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="448" mass="46791" checksum="47B809427F842DA5" modified="2017-04-12" version="1">MEAGRRVLIAGIMLSVFAIAFQTIGIATALPTIMGYFETPHLYPWAFTTFVSGMLVATIAAGRVADLKGPAGPMYAGFGLFVAGLVVGSLAPNVWVLLVARLIQGLGAGALNLTLSVTVAHGFDGRSRPKVMALISFCWLLPAFIGPPVAAALTRIDWRLVFALMLPLVFVSVAITRPGLRRVQADFEPDTDEVPRIAAWPTAAVAMAPSLILLAGQKLGWVSVASGVAGVALLVWGVPRILAPRTRGLGPGIPSVVLTRALQAGSFFAAETILLVTLQDLRGLTPFDVGLALTVGSVGWTLGSWLQSQGWVRLTRDAFITLGAIASSTGIAVIVVFAWVPSIHLFVGLLGWVISGLGMGLTMPSSAVAVMALSTQFEQGRHQSSMQVAESIGNAVITAVAGGLYTALLAAEPQKLSYTTALSATLVLSLAAVVLSRRIGRIANELHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG04</accession>
    <name>A0A1Q2CG04_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoribosylglycinamide formyltransferase</fullName>
            <ecNumber evidence="3">2.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">5'-phosphoribosylglycinamide transformylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">GAR transformylase</fullName>
            <shortName evidence="3">GART</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">purN</name>
        <name evidence="5" type="ORF">RPIT_09850</name>
        <name evidence="6" type="ORF">SAMN05428934_102336</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(6S)-10-formyltetrahydrofolate + N(1)-(5-phospho-beta-D-ribosyl)glycinamide = (6S)-5,6,7,8-tetrahydrofolate + H(+) + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide</text>
            <dbReference type="Rhea" id="RHEA:15053"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="EC" id="2.1.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Purine metabolism; IMP biosynthesis via de novo pathway; N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GART family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.2" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY57945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09850"/>
    <dbReference type="EnsemblBacteria" id="AQP45052">
        <property type="protein sequence ID" value="AQP45052"/>
        <property type="gene ID" value="RPIT_09850"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57945">
        <property type="protein sequence ID" value="SDY57945"/>
        <property type="gene ID" value="SAMN05428934_102336"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09850"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00126"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004644">
        <property type="term" value="F:phosphoribosylglycinamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08645">
        <property type="entry name" value="FMT_core_GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01930">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004607">
        <property type="entry name" value="GART"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001555">
        <property type="entry name" value="GART_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00639">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00373">
        <property type="entry name" value="GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="4">
        <location>
            <begin position="4"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="10-formyltetrahydrofolate binding" evidence="3">
        <location>
            <begin position="91"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>(6S)-10-formyltetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>(6S)-10-formyltetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
        </ligand>
    </feature>
    <feature type="site" description="Raises pKa of active site His" evidence="3">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY57945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="191" mass="20247" checksum="C92BDE0BC376AAB1" modified="2017-04-12" version="1">MTTRVVVLLSGSGTLCQALFDAIDAGEVEAQVVAVVSDRADAQGLERARARGLPAVAVPLAKGADRAEWDERLRDEVAAHAPDLVASAGFMKLLGPAFLARFAGLTINTHPALLPSFPGMHGPRDALRAGVKVSGATVFLVDDGVDTGRILLQGAVEVLPDDTEESLHERIKVVERRLLVQAVADWNKETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG22</accession>
    <name>A0A1Q2CG22_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_09525</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44995">
        <property type="protein sequence ID" value="AQP44995"/>
        <property type="gene ID" value="RPIT_09525"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09525"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="12"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="104"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="173" mass="19156" checksum="2DBA82A59716B1F3" modified="2017-04-12" version="1">MQARRRERFVSLYETHADRILLYCLRHLARATAEDAVADVFLTAWRRLDDVPEEPAAWLYATARNVIRNRYRAQATGIATAERVARLQDLTADSAEVTAGRRADLATALGALTDDEREALLLTVWDGLSGAEAASVLGCTPGALRVRLHRARQRMAAALHETSPEFAWEGSPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG41</accession>
    <name>A0A1Q2CG41_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GMP synthase [glutamine-hydrolyzing]</fullName>
            <ecNumber evidence="9">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">GMP synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Glutamine amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">guaA</name>
        <name evidence="12" type="ORF">RPIT_09925</name>
        <name evidence="13" type="ORF">SAMN05428934_102321</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Catalyzes the synthesis of GMP from XMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY57471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09925"/>
    <dbReference type="EnsemblBacteria" id="AQP45067">
        <property type="protein sequence ID" value="AQP45067"/>
        <property type="gene ID" value="RPIT_09925"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57471">
        <property type="protein sequence ID" value="SDY57471"/>
        <property type="gene ID" value="SAMN05428934_102321"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09925"/>
    <dbReference type="UniPathway" id="UPA00189">
        <property type="reaction ID" value="UER00296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="F:GMP synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="guaA_Cterm"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0067">ATP-binding</keyword>
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    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="11">
        <location>
            <begin position="198"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="225"/>
            <end position="231"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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            <dbReference type="ARBA" id="ARBA00022749"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
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            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
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        <source>
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        </source>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP45067.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY57471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="517" mass="56266" checksum="A1D74DED8D111D73" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGC4</accession>
    <name>A0A1Q2CGC4_9ACTN</name>
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        <submittedName>
            <fullName evidence="8">Iron ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Iron complex transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_10475</name>
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    </gene>
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP45168">
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    </dbReference>
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        <property type="protein sequence ID" value="SDY54447"/>
        <property type="gene ID" value="SAMN05428934_102210"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10475"/>
    <dbReference type="Proteomes" id="UP000188324">
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="ABC_BtuC-like"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF81345"/>
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    </dbReference>
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    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
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            <begin position="21"/>
            <end position="43"/>
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        <location>
            <begin position="72"/>
            <end position="92"/>
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    <feature type="transmembrane region" description="Helical" evidence="7">
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            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
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        <location>
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            <end position="227"/>
        </location>
    </feature>
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        <location>
            <begin position="247"/>
            <end position="275"/>
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    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
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        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY54447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="340" mass="35498" checksum="08E5603DE4AACE04" modified="2017-04-12" version="1">MSTLTLDRPTTGVAPDRPFNWAILSALLGVLVLSGVSVFTGVADLSPIDFLTGTATDEQKLNLVASRIPRTAAVLLAGASLALAGLLMQMLVRNRFVEPSTVGTSESAAVGLLIVAMLFPAAPLPLKMLVAIITALIGTALFLRVIRSLPPHAPVVAIPLVGIMLAGIIAAGTTFVAQRNDLLQSLGIWMAGDFSGVLRGRYEGLWLLAGVGVLMWLFADRFTVASLGKDTATSLGLSYRMTLNLGLGLVAVASAVTLVIVGSIAFVGLIVPNLISMWRGDNLRRNIGWAALAGSGFVLVCDLIARTINHPYEVPVGTVSGIIGGAIFLGLLLTGKLRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGE0</accession>
    <name>A0A1Q2CGE0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10590</name>
        <name evidence="3" type="ORF">SAMN05428934_102187</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY53705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45189">
        <property type="protein sequence ID" value="AQP45189"/>
        <property type="gene ID" value="RPIT_10590"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY53705">
        <property type="protein sequence ID" value="SDY53705"/>
        <property type="gene ID" value="SAMN05428934_102187"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10590"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY53705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="60" mass="6448" checksum="018CE9403D8EDA39" modified="2017-04-12" version="1">MSEPHTDPDRDPDVDAAPERPAGEITTGRRMLWLAGGGIGAYMVLRGVWGLATGEDQEQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGG0</accession>
    <name>A0A1Q2CGG0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_10625</name>
        <name evidence="8" type="ORF">SAMN05428934_102180</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY53501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10625"/>
    <dbReference type="EnsemblBacteria" id="AQP45194">
        <property type="protein sequence ID" value="AQP45194"/>
        <property type="gene ID" value="RPIT_10625"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY53501">
        <property type="protein sequence ID" value="SDY53501"/>
        <property type="gene ID" value="SAMN05428934_102180"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10625"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007343">
        <property type="entry name" value="Uncharacterised_pept_Zn_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30168">
        <property type="entry name" value="PTHR30168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04228">
        <property type="entry name" value="Zn_peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="60"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY53501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="294" mass="31180" checksum="D353DD2B9A3A8F18" modified="2017-04-12" version="1">MEFRSDARIDQSNVRYGGGGGRRGGRGMAVGGGLGGIIILVLMLLFGGGGIGDILGGGGAAQPQQQQPQENPNCQTGADIERDPECRWPAYVTAINDYWSQALEGYQPATTQLFSGQVGTACGTGSSEMGPFYCPGDNTVYIDTEFMGVLLNQLGAAGGYAAEAYIVAHEYGHHISNLTGQMREARAGGNDTGPESNAVRLELQADCYAGVWFKNAMNDPDGLIETVTQDDLNRIVDAARAVGDDHIQQQQGGRVVPESWTHGSSQMRQYWVAKGFQSGDPNVCDTFSTDDLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGG1</accession>
    <name>A0A1Q2CGG1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription-repair-coupling factor</fullName>
            <shortName evidence="8">TRCF</shortName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mfd</name>
        <name evidence="11" type="ORF">RPIT_10720</name>
        <name evidence="12" type="ORF">SAMN05428934_102161</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the C-terminal section; belongs to the helicase family. RecG subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the N-terminal section; belongs to the UvrB family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY52931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10720"/>
    <dbReference type="EnsemblBacteria" id="AQP45208">
        <property type="protein sequence ID" value="AQP45208"/>
        <property type="gene ID" value="RPIT_10720"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY52931">
        <property type="protein sequence ID" value="SDY52931"/>
        <property type="gene ID" value="SAMN05428934_102161"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10720"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000716">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair, DNA damage recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00969">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036101">
        <property type="entry name" value="CarD-like/TRCF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003711">
        <property type="entry name" value="CarD-like/TRCF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004576">
        <property type="entry name" value="Mfd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037235">
        <property type="entry name" value="TRCF-like_C_D7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005118">
        <property type="entry name" value="TRCF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02559">
        <property type="entry name" value="CarD_CdnL_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03461">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01058">
        <property type="entry name" value="CarD_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00982">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141259">
        <property type="entry name" value="SSF141259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143517">
        <property type="entry name" value="SSF143517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00580">
        <property type="entry name" value="mfd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="657"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="843"/>
            <end position="993"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP45208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY52931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="1175" mass="128869" checksum="E56E4383BF06C3F3" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGM0</accession>
    <name>A0A1Q2CGM0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Putative ABC transport system ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_10980</name>
        <name evidence="6" type="ORF">SAMN05428934_102107</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY51252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10980"/>
    <dbReference type="EnsemblBacteria" id="AQP45254">
        <property type="protein sequence ID" value="AQP45254"/>
        <property type="gene ID" value="RPIT_10980"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY51252">
        <property type="protein sequence ID" value="SDY51252"/>
        <property type="gene ID" value="SAMN05428934_102107"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10980"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="8"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY51252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="252" mass="27214" checksum="D79FF0DBEA651598" modified="2017-04-12" version="1">MSTPTALLSATGVRKSFPIDGSNIEVLHGVDLHITEGEFVAVMGPSGSGKSTLLYAVSGMDPVDAGDVHLAGTELTTLDGDGLADARRELMGFVFQQPTLLKDLPLLDNIVLTSALDKVGTPAERRARAEELMTRAGIWELRDRMTSQVSGGQLQRAGICRALMRRPRIIFGDEPTGALNSTAAGEIMDLLSDLNAEGTTLLVVTHDVRVAARAHRVVFMVDGQVTDELLLDADDEETRVDLVTRRVRELRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGP0</accession>
    <name>A0A1Q2CGP0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">8-oxo-dGTP pyrophosphatase MutT, NUDIX family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_11180</name>
        <name evidence="6" type="ORF">SAMN05428934_10268</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY50065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11180"/>
    <dbReference type="EnsemblBacteria" id="AQP45288">
        <property type="protein sequence ID" value="AQP45288"/>
        <property type="gene ID" value="RPIT_11180"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY50065">
        <property type="protein sequence ID" value="SDY50065"/>
        <property type="gene ID" value="SAMN05428934_10268"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11180"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="12"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY50065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="172" mass="19393" checksum="F60C681C76AE208A" modified="2017-04-12" version="1">MPDTFTDDRPVRERDAARVIVVADREVLLQGDTDPGVPGSRFWQTPGGGVDPDELNRAAAVRELEEETGLIVDQDDLEGPVAIRRLIRGYSDRILVQDETFYLLRTARFDAVPAGLSAREEERHVDTDWHRLDALPENTWPAELPRLALWRGEEMVDLGVVEESTVPVNRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGQ4</accession>
    <name>A0A1Q2CGQ4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lipoprotein antigen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_11155</name>
        <name evidence="4" type="ORF">SAMN05428934_10273</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY50206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11155"/>
    <dbReference type="EnsemblBacteria" id="AQP45283">
        <property type="protein sequence ID" value="AQP45283"/>
        <property type="gene ID" value="RPIT_11155"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY50206">
        <property type="protein sequence ID" value="SDY50206"/>
        <property type="gene ID" value="SAMN05428934_10273"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11155"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008691">
        <property type="entry name" value="LpqH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05481">
        <property type="entry name" value="Myco_19_kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544495" evidence="2">
        <location>
            <begin position="22"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY50206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="172" mass="17144" checksum="70F1C285DE2ABFAB" modified="2017-04-12" version="1">MNRVKVVLLAGAASVALLASACSGDGGAPAPVGQGTAAANSAVPTNEPLPSEIGTEAPEGGAAVRLGDIEEAITKVGCTSMNDDWTMSGSNEGGAKVALITSADRQTVVSASVVLADGKLVDYKGETGRADIAWDGESFTVTGQGTFMDLAAAEQDPEALETFVIKGACPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGR2</accession>
    <name>A0A1Q2CGR2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11305</name>
        <name evidence="3" type="ORF">SAMN05428934_10242</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY49312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45309">
        <property type="protein sequence ID" value="AQP45309"/>
        <property type="gene ID" value="RPIT_11305"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY49312">
        <property type="protein sequence ID" value="SDY49312"/>
        <property type="gene ID" value="SAMN05428934_10242"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11305"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544475" evidence="1">
        <location>
            <begin position="29"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY49312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="162" mass="16767" checksum="9EEAA615B9A7C4BC" modified="2017-04-12" version="1">MSKSPSRLVAAVASAAIAVSLSACTAGQWQYDAPPAAGVQEDLGGVKLRNVLILTDGSDAVLLGGIASRDEDTQVTGITYSPEQPDGTYGEPQELAFEVDIPKGQTVLIDGTDSSFPAEGLTVGRLADVTVNLADGGAVDMLVPVYSSEHSDFVEAWEQARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGU6</accession>
    <name>A0A1Q2CGU6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">D-ribose pyranase</fullName>
            <ecNumber evidence="2">5.4.99.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_11475</name>
        <name evidence="5" type="ORF">SAMN05428934_1028</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-ribopyranose = beta-D-ribofuranose</text>
            <dbReference type="Rhea" id="RHEA:25432"/>
            <dbReference type="ChEBI" id="CHEBI:27476"/>
            <dbReference type="ChEBI" id="CHEBI:47002"/>
            <dbReference type="EC" id="5.4.99.62"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.4.99.62" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY48189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11475"/>
    <dbReference type="EnsemblBacteria" id="AQP45341">
        <property type="protein sequence ID" value="AQP45341"/>
        <property type="gene ID" value="RPIT_11475"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY48189">
        <property type="protein sequence ID" value="SDY48189"/>
        <property type="gene ID" value="SAMN05428934_1028"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11475"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062193">
        <property type="term" value="F:D-ribose pyranase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048029">
        <property type="term" value="F:monosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005996">
        <property type="term" value="P:monosaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023750">
        <property type="entry name" value="RbsD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007721">
        <property type="entry name" value="RbsD_FucU"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05025">
        <property type="entry name" value="RbsD_FucU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102546">
        <property type="entry name" value="SSF102546"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY48189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="145" mass="15763" checksum="39E1DAF6EE937487" modified="2017-04-12" version="1">MLNGPLIHPELLDALGRAGHGSKILITDGNYPHETGAPARARRIYLNLAPGLLGVGQILDVLKQAVPIEQAGIMTPAPDAPPELRPDKIEAHDEYRAALPGVEFVEISRWDFYDEAKKDDVGIVIASGEQRIYANLLLTIGVRQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGY4</accession>
    <name>A0A1Q2CGY4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter substrate-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Carbohydrate ABC transporter substrate-binding protein, CUT1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_11680</name>
        <name evidence="7" type="ORF">SAMN05428934_106139</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11680"/>
    <dbReference type="EnsemblBacteria" id="AQP45376">
        <property type="protein sequence ID" value="AQP45376"/>
        <property type="gene ID" value="RPIT_11680"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93728">
        <property type="protein sequence ID" value="SDY93728"/>
        <property type="gene ID" value="SAMN05428934_106139"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11680"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006061">
        <property type="entry name" value="SBP_1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01037">
        <property type="entry name" value="SBP_BACTERIAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544487" evidence="5">
        <location>
            <begin position="27"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="28"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY93728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="444" mass="48292" checksum="4AE59AB5CE1EE24A" modified="2017-04-12" version="1">MITFKKALTATALASALLLTACGGDGDDPAPGATDPAMTTPAATSGETTGGETTGAGEAPAASGTINFFTDKAAWEPSFEEMNAASGDIDLEFTGYSDPVAYDTYIRQAFRTDDKPDLFTWHTGGKLQELAEQGLVAETTDIWAEAESEGLVPEGLKDQYTYDGKQYCVPLNVAYWAVYYNKQIFDDNGLTPPTTWEEMETVMQTLRDAGVTPFHQMNIIFEFVYFQALLAGQDPDTYLGILDGSASYTDEDVNVAVDKWEEMINRGDFIDPGVTGDPQALLMNGDVAMAYFGTFFTGQLTAIDAVSGEDYGIFMFPNLNPDTEEQPMILETGPLCVGAGSENEDTALAYSKWWLTTDAQTAWSQSRGDVSFNPNVEIEDPELSALVEAVNDGTRILPRYLEGSPQPVYQLSTELFGAFVTSPSDPRGMQERLQAAADDYWAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH01</accession>
    <name>A0A1Q2CH01_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbohydrate ABC transporter substrate-binding protein, CUT1 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Sugar ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_11390</name>
        <name evidence="4" type="ORF">SAMN05428934_10226</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY48769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45325">
        <property type="protein sequence ID" value="AQP45325"/>
        <property type="gene ID" value="RPIT_11390"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY48769">
        <property type="protein sequence ID" value="SDY48769"/>
        <property type="gene ID" value="SAMN05428934_10226"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11390"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544477" evidence="2">
        <location>
            <begin position="31"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY48769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="441" mass="46218" checksum="7F04081AEFEECD79" modified="2017-04-12" version="1">MKKALIGTAIAALILTGCGGGTTDTPTTGAETPATGGETTSATEAQEPVTLSFWHNATTGPGKAYWEETTAAFSEEHPNVSWEIQVIQNEDMDGRLQTALNAGDAPDLFMARGGGKLADMVAANQIMDVTDKLSEETKAAYGEGVVNTFNVDGKIYGLPTSLLPGGIFYSKDLFEQAGIEGTPETIDELNDAVAKLKEAGISPIALGGKDAWPAAHWYYFFVLRQCSQETIEGAAAQDFSDPCWLEAGQNLKEFADTEPFNQGFLTTSAQQGAGSSAGLLANKQAAMELMGAWNPGVIASLTPDEQPLPDLGWFPFPAIEGGEGDPTAMMGGADGYSCHIDAPEVCADFMNFYAEKEQQEGYAEAFNTLPANAEAAEAVSDPALQDILGAYSDAAYMTVWLDTMLGQNVGNALNAGVVNMLAGQGTPEDIVSSVESAAAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH08</accession>
    <name>A0A1Q2CH08_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">NH(3)-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="4 6">6.3.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">nadE</name>
        <name evidence="9" type="ORF">RPIT_11715</name>
        <name evidence="10" type="ORF">SAMN05428934_106132</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>ATP + deamido-NAD(+) + NH4(+) = AMP + diphosphate + H(+) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:21188"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 7">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (ammonia route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the NAD synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.5" evidence="4 6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11715"/>
    <dbReference type="EnsemblBacteria" id="AQP45383">
        <property type="protein sequence ID" value="AQP45383"/>
        <property type="gene ID" value="RPIT_11715"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93580">
        <property type="protein sequence ID" value="SDY93580"/>
        <property type="gene ID" value="SAMN05428934_106132"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11715"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00333"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008795">
        <property type="term" value="F:NAD+ synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00193">
        <property type="entry name" value="NadE_ammonia_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022926">
        <property type="entry name" value="NH(3)-dep_NAD(+)_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="PTHR23090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00552">
        <property type="entry name" value="nadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_synthase" evidence="8">
        <location>
            <begin position="24"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="46"/>
            <end position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="259"/>
            <end position="260"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY93580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="282" mass="31330" checksum="646027A2C7AD89BB" modified="2017-04-12" version="1">MRPLQKLIVQEFGVKPEIDPAEEVEARIQFLADYLTATGTAGYVLGISGGLDSTLAGRLAQSAVERVRQEGREATFVAIRLPYRIQHDEADAVEAMDFVAADREVTFNIGDAVDAFESEYSASVGREISDFNKGNVKARLRMVAQYAVAGDNRMLVIGTDHGAESVMGFFTKFGDGGADILPLFGLNKRQNRHLLRHLGAPERIWAKVPTADLLDDKAGQPDEVELGISYDHIDDYLEGREVPDAAAERIEQVWWRSRHKRTVPVTITDGWWREQYPGGDRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH56</accession>
    <name>A0A1Q2CH56_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_12080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12080"/>
    <dbReference type="EnsemblBacteria" id="AQP45449">
        <property type="protein sequence ID" value="AQP45449"/>
        <property type="gene ID" value="RPIT_12080"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12080"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="476" mass="49468" checksum="B0A9BE2DC7D8AB13" modified="2017-04-12" version="1">MINSAGDAVDPSTLLGEVALDVSILGEDGDPRSLATLGADTLNDAVELDTEGLEPGKQTLRMRLNVTTADAVLNSGESVSGTELTPQVVDVPLVIEPPLGYPSLDGMVDFGAAEGPPALSATLKVKGPGCLWLVPNSAVVEASPVEVTQASISSANSTPDSCFSVSDGLDAELPLLLTSDDAGNGALQGTFDVSMMPLEGGETQTLPVRFTAELSKDLNPTSFWLTLVIAALFGPGIPILLAYLLKFLLASKIPPGGLLAVSMDVEVHDGSVLRDGRRLAWRAEDAREFKSVTGGGTRRLEVGGAVLVARMGASPFGSGYVLVEAGDRIGVSKHKPMPHGRRRQALLPLALTGQWVALFTPGDRQHVELLVLTAPGARPEARDALLEDAERRVPALIDELVEDAGDTDTPGNATAAAAGDPFGLDGGSAGWTPSASPRLTEIKRATSDRPSKQSPPMAPPPQASDDQSGSWDPFAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHF0</accession>
    <name>A0A1Q2CHF0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pseudouridylate synthase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12330</name>
        <name evidence="3" type="ORF">SAMN05428934_10610</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY90879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12330"/>
    <dbReference type="EnsemblBacteria" id="AQP45490">
        <property type="protein sequence ID" value="AQP45490"/>
        <property type="gene ID" value="RPIT_12330"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY90879">
        <property type="protein sequence ID" value="SDY90879"/>
        <property type="gene ID" value="SAMN05428934_10610"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12330"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="1">
        <location>
            <begin position="103"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY90879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="314" mass="35899" checksum="6EB7F60E168C6CD6" modified="2017-04-12" version="1">MPPKSPLPPRHGLQAAWVRTPDRDPDNALPWPTMRDWLIDKLAPSPEDVDEMLRRGAFVDDRGRPWTGREVYRPHTFVWFHRELRDEAEVPGELTVLHRDERIVVLDKPHFLSTIPRGRHVVQSAVVKARQALDLPHLSAAHRLDRGTAGVLLMTTEKRWRAAYHTVFSDRSAVKVYHAIAPHDPDLSFPLRVDSHLIKRVGTMQAETLDLPPNSATEIDLLEVRGQHALYEVRPLTGKTHQIRAHFNQLGIPLVGDPLYPEVLPTEIDDFSTPLRLLAYSLEFRDPVDGEHRRFVSRRQLTWPTRMLADGGGI</sequence>
</entry>
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        <submittedName>
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    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY80348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12470"/>
    <dbReference type="EnsemblBacteria" id="AQP45515">
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        <property type="gene ID" value="RPIT_12470"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY80348">
        <property type="protein sequence ID" value="SDY80348"/>
        <property type="gene ID" value="SAMN05428934_104192"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="NT_sf"/>
    </dbReference>
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        <property type="entry name" value="Polbeta"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Polbeta" evidence="2">
        <location>
            <begin position="104"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY80348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="197" mass="20471" checksum="2EB6A6ABD9D7A55B" modified="2017-04-12" version="1">MRFEVAFGGLIPGASGAVLAVLLRTGVPLTGRQVHGLVRDQCSLWSVQQALASLADLGVVESRAVGRAMVHTINEDHYAIQPLRVLLDPIAALREAVRAVVGSSVDVVVLFGSVARGEATAESDVDLAVVAPSGWEGRTELEDAVRTRLGNDCDVLVFTPEEFGRLAGSGEEPVVAQIVADGVVLLGSLPQATVGVA</sequence>
</entry>
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    <accession>A0A1Q2CHH9</accession>
    <name>A0A1Q2CHH9_9ACTN</name>
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        </submittedName>
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    </gene>
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
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            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
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    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP45578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY78393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12815"/>
    <dbReference type="EnsemblBacteria" id="AQP45578">
        <property type="protein sequence ID" value="AQP45578"/>
        <property type="gene ID" value="RPIT_12815"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY78393">
        <property type="protein sequence ID" value="SDY78393"/>
        <property type="gene ID" value="SAMN05428934_104124"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12815"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="match status" value="7"/>
    </dbReference>
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        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035234">
        <property type="entry name" value="IgGFc-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17517">
        <property type="entry name" value="IgGFc_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
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        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544509" evidence="1">
        <location>
            <begin position="33"/>
            <end position="2166"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="446"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="839"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="893"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="1007"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="1091"/>
            <end position="1143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY78393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="2166" mass="225933" checksum="35EB77DE8E840BF4" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHK2</accession>
    <name>A0A1Q2CHK2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome bd-I ubiquinol oxidase subunit 2 apoprotein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Cytochrome d ubiquinol oxidase subunit II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_12925</name>
        <name evidence="9" type="ORF">SAMN05428934_104102</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome ubiquinol oxidase subunit 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12925"/>
    <dbReference type="EnsemblBacteria" id="AQP45598">
        <property type="protein sequence ID" value="AQP45598"/>
        <property type="gene ID" value="RPIT_12925"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY77816">
        <property type="protein sequence ID" value="SDY77816"/>
        <property type="gene ID" value="SAMN05428934_104102"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12925"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003317">
        <property type="entry name" value="Cyt-d_oxidase_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43141">
        <property type="entry name" value="PTHR43141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02322">
        <property type="entry name" value="Cyt_bd_oxida_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000267">
        <property type="entry name" value="Cyt_oxidse_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00203">
        <property type="entry name" value="cydB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="317"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY77816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="357" mass="38867" checksum="50D1A65EF6F8E02E" modified="2017-04-12" version="1">MIHLLETVSVPTLPLVWFLLIAVLWTGFFFLEGFDFGVGMLIPVLGKNDRERRVVVNTIGPVWDGNEVWLITAGGAMFAAFPGWYSTLFSGLYLPLLLVLIGLILRGVAFEYRSKHPGSRYRAMLDWFAIVGSFLPALVFGIGFANFVVGLPNDGLLFDGSFWGLFGPFALLGGVMLVVLFLVHGSAFIALKTKGLIHDRAEAFGARFGWAATALVAVFVISQNLFYPATSEFGDFAVLAWAVGVVSIVSIAAATVMIKRGRDGWGFVLTGASVVTLFVGIFLKIYGNLGFAQDETVAATERLNIITAASSPTTLTIMTWAAVIFVPIVLAYQSWTYWVFSKRISLKNIPEEVSPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHN1</accession>
    <name>A0A1Q2CHN1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable endolytic peptidoglycan transglycosylase RlpA</fullName>
            <ecNumber evidence="3">4.2.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rlpA</name>
        <name evidence="6" type="ORF">RPIT_13020</name>
        <name evidence="7" type="ORF">SAMN05428934_10483</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the RlpA family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.-" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13020"/>
    <dbReference type="EnsemblBacteria" id="AQP45614">
        <property type="protein sequence ID" value="AQP45614"/>
        <property type="gene ID" value="RPIT_13020"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY77306">
        <property type="protein sequence ID" value="SDY77306"/>
        <property type="gene ID" value="SAMN05428934_10483"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13020"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008932">
        <property type="term" value="F:lytic endotransglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000270">
        <property type="term" value="P:peptidoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02071">
        <property type="entry name" value="RlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034718">
        <property type="entry name" value="RlpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009009">
        <property type="entry name" value="RlpA-like_DPBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012997">
        <property type="entry name" value="RplA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03330">
        <property type="entry name" value="DPBB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="SSF50685"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00413">
        <property type="entry name" value="rlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5015011042" description="Probable endolytic peptidoglycan transglycosylase RlpA" evidence="3">
        <location>
            <begin position="28"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="DPBB_1" evidence="5">
        <location>
            <begin position="198"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY77306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="284" mass="31249" checksum="0000313335E125E0" modified="2017-04-12" version="1" precursor="true">MFKRLLFAGLAAITGATVGLVAPTAQAVETIQYTQPGDHLVNGRYWRTTCENYSPTVVRCNTDIFATKVVKVDGHHVVHNGWTFNNLTYLPSERSQWEGNPLATTGEWTASDGRLWKAECDTDLTGANGCRAWAWTTVVAHENGKFVQRDQWQFNNIIQFSTTDIPPVTTIPAPAPPLAGVPVEKEPESPLAWQSCKVSYYWQGYRTANGEIYDPNGLTAAHKTLPFNTRVRVQNPANGKEVVVRINDRGPFIAGRCLDLSRAAMQAIGGTSAGVITANYQVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHT0</accession>
    <name>A0A1Q2CHT0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13385</name>
        <name evidence="3" type="ORF">SAMN05428934_10410</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY75239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13385"/>
    <dbReference type="EnsemblBacteria" id="AQP45679">
        <property type="protein sequence ID" value="AQP45679"/>
        <property type="gene ID" value="RPIT_13385"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY75239">
        <property type="protein sequence ID" value="SDY75239"/>
        <property type="gene ID" value="SAMN05428934_10410"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13385"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY75239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="305" mass="31885" checksum="955119AB78864F18" modified="2017-04-12" version="1">MSNDIESTVAKHAAELASQPEGGFPAQEQAPPGLTSKMDPVPDHGEESYEGHGKLQGLRALITGGDSGIGRAVAIAFAREGADVAIAHLPEEQSDADDTLEFVRKEGVKGFSIPGDLQDTDTCARTVEQAVESLGGLDILVNNAAYHFTRGDAGGLEGLKQENVSRVLRLNIEAILWLTKAAVPHLGKGSSIINTSSIQSFEPSGRLLEYAATKAAVNNLTVNLAEELGPKGIRVNAVAPGPIWTPLQPATRDGEEMKKFGADTPLGRAGQPAELAPAYVFLASPRDASYVSGTIIGVTGGKAAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHV5</accession>
    <name>A0A1Q2CHV5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phytoene synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13190</name>
        <name evidence="4" type="ORF">SAMN05428934_10449</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carotenoid biosynthesis; phytoene biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY76370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13190"/>
    <dbReference type="EnsemblBacteria" id="AQP45645">
        <property type="protein sequence ID" value="AQP45645"/>
        <property type="gene ID" value="RPIT_13190"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY76370">
        <property type="protein sequence ID" value="SDY76370"/>
        <property type="gene ID" value="SAMN05428934_10449"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13190"/>
    <dbReference type="UniPathway" id="UPA00799"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:farnesyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00683">
        <property type="entry name" value="Trans_IPPS_HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019845">
        <property type="entry name" value="Squalene/phytoene_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044843">
        <property type="entry name" value="Trans_IPPS_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033904">
        <property type="entry name" value="Trans_IPPS_HH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01212">
        <property type="entry name" value="Phytoene_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01018">
        <property type="entry name" value="Squalene/Phytoene_Synthase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01045">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY76370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="298" mass="33206" checksum="2BF37CB594F2EDB5" modified="2017-04-12" version="1">MTALDAGYQRAAELTKLHGTTYYWGARLLPESQRRDVFAVYALCRLADDIVDEPETVAPADTAVPPNGTPEERLAAFRATFFDALANPTGDHPPVMAAIVDSISRRGTDPECFDRFFDAMAADLTKTSWATWEELRDGYMEGSAAVIGEMMLPVLEPFTDKAMGPARALGNAFQLTNFLRDVEEDLDRGRVYLPQEDLARHGADPSLRRVTPEWRSMMAEQVARNRELYAEGERGLAMLPRRSRLCVGTALVLYSRILDRIEAADYDVFSGRIRVPDREKVALTARALTLGVPKLSFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHW2</accession>
    <name>A0A1Q2CHW2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SURF1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13555</name>
        <name evidence="3" type="ORF">SAMN05428934_11188</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SURF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ13174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13555"/>
    <dbReference type="EnsemblBacteria" id="AQP45709">
        <property type="protein sequence ID" value="AQP45709"/>
        <property type="gene ID" value="RPIT_13555"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ13174">
        <property type="protein sequence ID" value="SDZ13174"/>
        <property type="gene ID" value="SAMN05428934_11188"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13555"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06662">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002994">
        <property type="entry name" value="Surf1/Shy1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02104">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ13174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="237" mass="25119" checksum="A12431D107F74B1B" modified="2017-04-12" version="1">MGLRAKQAVALAAGVVLAIVMVLLGLWQQASYEESTRDVSAERAAMEPVSLLDNIAEDGSIEDIYGRRVQVSGVYEELPTLFVGSEPPLRVVGALRTTDDRVLAVVRGASDLPDAPPPPSGQQDITGIFLAPDLATDRVADGADLGSLRIQALAQDWPSPLIAGYVTLSADDAAAQGLEPAPLLLPEAEGSATHRGYALQWWVFAAGAIAFGVYAARGLEQDEKKRQRRAAETHPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI26</accession>
    <name>A0A1Q2CI26_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Colanic acid/amylovoran biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14015</name>
        <name evidence="3" type="ORF">SAMN05428934_11716</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000017">
        <property type="protein sequence ID" value="SDZ20969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14015"/>
    <dbReference type="EnsemblBacteria" id="AQP45778">
        <property type="protein sequence ID" value="AQP45778"/>
        <property type="gene ID" value="RPIT_14015"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ20969">
        <property type="protein sequence ID" value="SDZ20969"/>
        <property type="gene ID" value="SAMN05428934_11716"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14015"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007345">
        <property type="entry name" value="Polysacch_pyruvyl_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04230">
        <property type="entry name" value="PS_pyruv_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PS_pyruv_trans" evidence="1">
        <location>
            <begin position="20"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ20969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="375" mass="41535" checksum="21AF64F8A76B5273" modified="2017-04-12" version="1">MSSTKTRSLRIYVHAYWQQNLGDDLFVKVLCERYPEVLFYGACSRRKSRAFEALDNFRRVPRLARVDRILSRLSLGPLLGPALERLYKARSDAVVNIGGSIFIEREGWRQRMPAMRARFGSGKQTYVVGSNFGPYEDPHFLDEYKALLRGGADVCFRDKVSAELFEELPNCRYAPDVILSMDPGETADHGTAVISVIDLETRPSLREHSNAYTTKLSEVALACIAAGLDVVLMSFCRSEQDVAAAKRLSQELDKAGASVRSYTYDGDLLAALTLLSTASVIIGTRFHAVILAWVFGKRVLPISYSPKTEHVLRDLAFPGEWINLEEIAELDVANSVSELLRSAPFAVGELRAMAEQQFAGLDAFVAQPLGSRSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI37</accession>
    <name>A0A1Q2CI37_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">dTDP-glucose 4,6-dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_14070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polysaccharide synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14070"/>
    <dbReference type="EnsemblBacteria" id="AQP45789">
        <property type="protein sequence ID" value="AQP45789"/>
        <property type="gene ID" value="RPIT_14070"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14070"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05237">
        <property type="entry name" value="UDP_invert_4-6DH_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003869">
        <property type="entry name" value="Polysac_CapD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02719">
        <property type="entry name" value="Polysacc_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Polysacc_synt_2" evidence="3">
        <location>
            <begin position="274"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="588" mass="64535" checksum="E13A4E84AB1D01B7" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI38</accession>
    <name>A0A1Q2CI38_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14005</name>
        <name evidence="3" type="ORF">SAMN05428934_11719</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000017">
        <property type="protein sequence ID" value="SDZ21024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14005"/>
    <dbReference type="EnsemblBacteria" id="AQP45777">
        <property type="protein sequence ID" value="AQP45777"/>
        <property type="gene ID" value="RPIT_14005"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ21024">
        <property type="protein sequence ID" value="SDZ21024"/>
        <property type="gene ID" value="SAMN05428934_11719"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14005"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="2"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ21024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="357" mass="40542" checksum="80C727B50CF926B9" modified="2017-04-12" version="1">MIVPIYNAEKYLSDTLKSLTAQTLDTLEIILVDDNSTDSSPIICKKFADVDKRIRIFTNTTQMGVSASRNLGLRHARGAYFAFVDSDDIVHEEMYMRLFKTAVAADADIVISNLRVVHDGGSRQVVTYNRHPKNVQLGRHYLMTNVIAPLVGIKIDPSLFVGNSACDKLFRASNARNGGITFDEGRLRFEDRLFVVEFLATAKSVTFVDEAFYSYIRRPKSLQTRYNPGELDAVISNQLRYRELFEKDFDFDSPMAVQYRVSAITDVIFSTLSHSRGHSEANKRTTEVLCNPHVVEWYSKLQPPGATPFYRVVRRCINSNHYTLAHLLFQAKFLPVRLKLLARRLAVRTGMMPQSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI54</accession>
    <name>A0A1Q2CI54_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MFS transporter, DHA3 family, multidrug efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14080</name>
        <name evidence="3" type="ORF">SAMN05428934_1174</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000017">
        <property type="protein sequence ID" value="SDZ20764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45791">
        <property type="protein sequence ID" value="AQP45791"/>
        <property type="gene ID" value="RPIT_14080"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ20764">
        <property type="protein sequence ID" value="SDZ20764"/>
        <property type="gene ID" value="SAMN05428934_1174"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14080"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="406"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ20764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="474" mass="50615" checksum="F0EC79A8BAD7B8F2" modified="2017-04-12" version="1">MVRCPVGIRSLTRAQTFNHVLGNTAAAMLGTTFIWFGITFWAYLETRSVLATSFLGGAYMLGMAVLGVPFGTLIDRHHKHRVMVFSAVATSIVFSLAAAVFLLTPPDRLTDLGQPWFWLFCGLILMGGLLANIRSIALSTCVTILVDSERRANANGLVGTVNGMMMMVTGVLSGLAIGQLGLLWTLLISLAVVLLSLVHLLTIRIPEPEIVHVEGAPKAVDFKGAWAAVVAVPGLIGLILFTTFNNFLGGVFMGLLDPYGLELVSVEVWGILFGLSGIGFIVGGAIIAQRGLGRLPLRSLLFSCLGMWIVAGGFTIRDSVVLLVVGMFLYMVLIPFIEGAEQTLLQQVVPLAKQGRVFGFAQAVEVSAAPISAFIIGPVAQFWLIPHAESPRGQRQWEWLLGTGDARGIALVFVLVSVGGLILTSLVFFTKTYRRLNATYEAGDVNKDIAAFAPGEAADPIPGPDPLGKGHAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI68</accession>
    <name>A0A1Q2CI68_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_14165</name>
        <name evidence="10" type="ORF">SAMN05428934_11215</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16845"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 8">Belongs to the citrate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ14451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14165"/>
    <dbReference type="EnsemblBacteria" id="AQP45807">
        <property type="protein sequence ID" value="AQP45807"/>
        <property type="gene ID" value="RPIT_14165"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ14451">
        <property type="protein sequence ID" value="SDZ14451"/>
        <property type="gene ID" value="SAMN05428934_11215"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14165"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00717"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004108">
        <property type="term" value="F:citrate (Si)-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06114">
        <property type="entry name" value="EcCS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024176">
        <property type="entry name" value="Citrate_synthase_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010953">
        <property type="entry name" value="Citrate_synthase_typ-I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001369">
        <property type="entry name" value="Citrate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="SSF48256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01798">
        <property type="entry name" value="cit_synth_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001369-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ14451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="428" mass="47663" checksum="14D35E330A156FBC" modified="2017-04-12" version="1">MTDSGVLKYGELELELPIVEATQGNNGFDISKVLATTGATTLDPGFVNTASCTSAITFIDGDEGILQYRGYPIEQLAEKATFIEVAYLLIYGELPTQEQLDRFSGKISRRMMLDERLKELYRSFPRGAHPMQVLAAGIMALGAFHRDNLSVHDPAQVEEASLRLLGSMPTLAAYAYKSSVGEPFLYPQTRLGYVENYLRLSFGTPQEEYEIDPDIVRAFETLFILHADHEQNASTSTVRLVGSADANIYASMSSGVNALSGPLHGGANQAVLEMLARINDEGLDIKEFVSQVKDKKSGVKLMGFGHRVYKNYDPRAKIIKGHADQLLRKTGASNALLDMALELEETALNDDYFIERKLYPNVDFYTGLIYEAMGFPAQHFTALFALGRLPGWIAQWREQHADPARKIGRPRQIYVGEKDRTYSPINER</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI69</accession>
    <name>A0A1Q2CI69_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_14095</name>
        <name evidence="4" type="ORF">SAMN05428934_1171</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000017">
        <property type="protein sequence ID" value="SDZ20716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45794">
        <property type="protein sequence ID" value="AQP45794"/>
        <property type="gene ID" value="RPIT_14095"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ20716"/>
        <property type="gene ID" value="SAMN05428934_1171"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14095"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544523" evidence="2">
        <location>
            <begin position="37"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ20716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="139" mass="13868" checksum="03A91BF147319F3C" modified="2017-04-12" version="1">MGEKIPRAGGIALVIVGAVLAGWFAAAIAAPPLAPASEPAIVVTVVPPAPSVSPSPAPTTPSPSASPTPSVSPTPSAEVTQSPAVVAPPPAASPAPPKQTVAPKPVPKPKPKPVYVDDDDDDDDDDDDDDDDDDDDDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CID8</accession>
    <name>A0A1Q2CID8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Deoxyribonuclease IV</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">Endonuclease IV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_14475</name>
        <name evidence="10" type="ORF">SAMN05428934_109121</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AP endonuclease 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14475"/>
    <dbReference type="EnsemblBacteria" id="AQP45864">
        <property type="protein sequence ID" value="AQP45864"/>
        <property type="gene ID" value="RPIT_14475"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06913">
        <property type="protein sequence ID" value="SDZ06913"/>
        <property type="gene ID" value="SAMN05428934_109121"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14475"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001719">
        <property type="entry name" value="AP_endonuc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018246">
        <property type="entry name" value="AP_endonuc_F2_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21445">
        <property type="entry name" value="PTHR21445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00518">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00730">
        <property type="entry name" value="AP_NUCLEASE_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00731">
        <property type="entry name" value="AP_NUCLEASE_F2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51432">
        <property type="entry name" value="AP_NUCLEASE_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="8">
        <location>
            <begin position="15"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ06913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="264" mass="27385" checksum="AC2AFCBD52AA3253" modified="2017-04-12" version="1">MTALFGAHVNSTDPLADAAALGADIVQIFLGDPQSWKKPATLFPGGAEALRNAAEAAGVKIVVHSPYVLNVASTNNRIRIPSRKLLQQTVTEAAAVGAIGVVVHGGHVTADEDPAVGFANWRKCVDGLDLSVPIFIENTAGGNNAMARHEGAIERLWEALAGSPNFDSVGFCLDTCHAHAGGAELDGLVDRVRAITGRIDLVHCNDSRDPAGSGADRHANLGEGLADPDALVRIVASAGAPVILETPGGVAEHLDDLAWLRARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIE3</accession>
    <name>A0A1Q2CIE3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">6-phosphogluconolactonase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_14575</name>
        <name evidence="2" type="ORF">SAMN05428934_10999</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14575"/>
    <dbReference type="EnsemblBacteria" id="AQP45881">
        <property type="protein sequence ID" value="AQP45881"/>
        <property type="gene ID" value="RPIT_14575"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06490">
        <property type="protein sequence ID" value="SDZ06490"/>
        <property type="gene ID" value="SAMN05428934_10999"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14575"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="SSF51004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ06490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="333" mass="35597" checksum="E3F7A8F4995CDE17" modified="2017-04-12" version="1">MTRLVLIANAGDGTISTLAINREPNPRLEVLATSGDVKGCSTFAIDPERDLVFAATKDPSIAVLRLDRESGELTELSRRPVDAPLAYLALTPDGTSLLGASYHDGFGEAWPVDGEGLGEPHSRFEYANLHAIVAADDNVYAPSLGDDLVAQFRLEDGELKPLSPGAVNAPAGSGPRHLIVDGQHVYLLTEFSGEVIRYSRGDNGGLSEEQRTIVVDPDAGLSRSRYGADPMEEHLIWGADLHRGGRFLFTSERTTSTIATVEVGPDGELGDVLAHTRVEQQPRGFAVTPDGEFLISVGERSTFASLFAIHDDGSLEQVSRVGIGAGANWVRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIF9</accession>
    <name>A0A1Q2CIF9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Anti-sigma-K factor rskA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_14340</name>
        <name evidence="4" type="ORF">SAMN05428934_11250</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ15140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14340"/>
    <dbReference type="EnsemblBacteria" id="AQP45840">
        <property type="protein sequence ID" value="AQP45840"/>
        <property type="gene ID" value="RPIT_14340"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ15140">
        <property type="protein sequence ID" value="SDZ15140"/>
        <property type="gene ID" value="SAMN05428934_11250"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14340"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018764">
        <property type="entry name" value="Anti-sigma_K_RskA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10099">
        <property type="entry name" value="RskA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ15140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="208" mass="22447" checksum="2403BBA7372349E6" modified="2017-04-12" version="1">MSEESNYTLDDVARRFRRAVAQDPQWSDPSPGTWEAIAAATGVAPSQSPAPDASEPQAAPSVSRRGWLFGAGGLVVGAIAGAVGMRMADGFFDDLEEAVRRAELTPLDRPDQRLGTAELLRQQFGYSLSVEVPEGVSNPDGYVEVWLINTDGQRMVSVGVFAADSIGRFSIDEALIEGGYLIVDLSNEQFDDEPRHSGDTIMRGELRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIG3</accession>
    <name>A0A1Q2CIG3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted PurR-regulated permease PerM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_14700</name>
        <name evidence="8" type="ORF">SAMN05428934_10979</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14700"/>
    <dbReference type="EnsemblBacteria" id="AQP45901">
        <property type="protein sequence ID" value="AQP45901"/>
        <property type="gene ID" value="RPIT_14700"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06099">
        <property type="protein sequence ID" value="SDZ06099"/>
        <property type="gene ID" value="SAMN05428934_10979"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14700"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ06099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="389" mass="40896" checksum="4CD66FB536EBFDF8" modified="2017-04-12" version="1">MSLIPALRRVFGPTPPPPVQPVIVQVPQAPEEDKRADLEPEIPRGLTVAAGYAWRLLLLGVAVVAIFQVLAYFSQITVPVGIAILLAAMLYPVVTLLRRWGWPPALVAIVSLLLLVVVVGGLLTFVGTQVAAEWPALLVQSREGFQALVAWLATLPFGIDQDRLNDWIAQGTAWLQGQSSALAGAAASVGAAFGNFFAGLATALVAAFFFAYQGRRIFTGAVEVLLPRHYRASVDRAALRGWTSLVAYMRSAVIVAAVDAAGVALAALILRVPLVAALFALTFFLSFIPIVGATLAGAVAVMLALVTHGWVSALIMLGAVILVMQLESTFLQPLVMGKAVDLHPLAVLLGITAGAIISGILGALLAIPVLAFGVAFVRSLRVGELEQVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIH7</accession>
    <name>A0A1Q2CIH7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_00325</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00325"/>
    <dbReference type="EnsemblBacteria" id="AQP45936">
        <property type="protein sequence ID" value="AQP45936"/>
        <property type="gene ID" value="RPIT_00325"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00325"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="170"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="230"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="445" mass="47173" checksum="B1E6C8B0A6AA3C8C" modified="2017-04-12" version="1">MTGASVALSVLLVGSAVFAITRWSLLEQLDRELVGVAQSAARSIQQSVADGQDGFRLELLGSADGLLSVVSSDGTVVSLPGESAAILPQSDEIAVARLRSGSSARTVIADGITYRAVSVPLNLTDGDYAVMYARPTAALEATLASLWLVMVAAGILGLMTSTIAALWTAQAVLAPVRRLSQAVKSVTQTDQLNPIRIYGRDDLGELTRSFNTMLKSLQTSREQQTQLIADAGHELRTPLTSMRTNVELLVADEKSGMLPDGARAVILADVAAQLGEFSALIGDLVALTRDDHLQRPHEPLDLAEVVDSAIARAKRRGPGIHFDIQLEPTPIMGDASTLERAITNLLDNAVKFSPPDGTITVHLEGGALTVIDDGPGIDEDDLPLIFDRFFRSDKARNTPGTGLGLSIVLHTTHAHGGTVKASNAPGRGARFVLRLPVVDLVEHEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIK5</accession>
    <name>A0A1Q2CIK5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peroxynitrite isomerase</fullName>
            <ecNumber evidence="1">5.99.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Ferric nitrobindin</fullName>
            <shortName evidence="1">Nb(III)</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01805</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>peroxynitrite = nitrate</text>
            <dbReference type="Rhea" id="RHEA:63116"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:25941"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="1">Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nitrogen metabolism.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the nitrobindin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.99.-.-" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01805"/>
    <dbReference type="EnsemblBacteria" id="AQP45968">
        <property type="protein sequence ID" value="AQP45968"/>
        <property type="gene ID" value="RPIT_01805"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01805"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062213">
        <property type="term" value="F:peroxynitrite isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07828">
        <property type="entry name" value="lipocalin_heme-bd-THAP4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01297">
        <property type="entry name" value="nitrobindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022939">
        <property type="entry name" value="Nb(III)_bact/plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045165">
        <property type="entry name" value="Nitrobindin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014878">
        <property type="entry name" value="THAP4-like_heme-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15854">
        <property type="entry name" value="PTHR15854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08768">
        <property type="entry name" value="THAP4_heme-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="SSF50814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THAP4_heme-bd" evidence="2">
        <location>
            <begin position="13"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXWXGXG" evidence="1">
        <location>
            <begin position="21"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="165" mass="18192" checksum="1CDA5D2057B3D471" modified="2017-04-12" version="1">MDIEVPEGLNPALTALGWLVGRWEGTGNGTDHEGNDFEFEQRIEFSHNGSDYLYYASQTFLLGDDGAEAEPLGVETGFWRPKADASLEVVLASADGWTEVLLGKIAVTRIDLLTDAVVRTESAQVSHASGQRLYGKVEGDLMYALDRSTAEHALRPHMWARLKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIL3</accession>
    <name>A0A1Q2CIL3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">STAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_00770</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00770"/>
    <dbReference type="EnsemblBacteria" id="AQP45944">
        <property type="protein sequence ID" value="AQP45944"/>
        <property type="gene ID" value="RPIT_00770"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00770"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="PTHR11814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="243"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="329"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="384"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="6">
        <location>
            <begin position="451"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="560" mass="57682" checksum="C256B2625E10456E" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIW6</accession>
    <name>A0A1Q2CIW6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase</fullName>
            <ecNumber evidence="8">5.3.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hisA</name>
        <name evidence="10" type="ORF">RPIT_06360</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:15469"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="5.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 8 9">Belongs to the HisA/HisF family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.16" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06360"/>
    <dbReference type="EnsemblBacteria" id="AQP46052">
        <property type="protein sequence ID" value="AQP46052"/>
        <property type="gene ID" value="RPIT_06360"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06360"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00009"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003949">
        <property type="term" value="F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004640">
        <property type="term" value="F:phosphoribosylanthranilate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04732">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01014">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010188">
        <property type="entry name" value="HisA/PriA_Actinobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044524">
        <property type="entry name" value="Isoase_HisA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023016">
        <property type="entry name" value="Isoase_HisA-like_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090">
        <property type="entry name" value="PTHR43090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01919">
        <property type="entry name" value="hisA-trpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7 8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP46052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="245" mass="25862" checksum="DD0F9EE4FC59EA96" modified="2017-04-12" version="1">MEKLQLLPAVDVQGGQAVQLVQGIAGTQKEFGDPLAAAKRWQDGGAEWLHLVDLDAAFGRGSNAELLRDIVGQLDMLVEISGGIRDDASLERALATGARRVNIGTAALEQPQWCERIIAEHGDKIAIGLDVRGENLAARGWTTEGGPWPETLDRLVAAGCERFVVTDVNADGMLTGPNVELLLAVARRSGRKVIASGGISSLDDLRALRAHVDDGVEGAIIGTALYVGRFTIEEALAVAEGEPNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIY0</accession>
    <name>A0A1Q2CIY0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell division protein FtsI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_04000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04000"/>
    <dbReference type="EnsemblBacteria" id="AQP46005">
        <property type="protein sequence ID" value="AQP46005"/>
        <property type="gene ID" value="RPIT_04000"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04000"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013066314" evidence="2">
        <location>
            <begin position="28"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_dimer" evidence="4">
        <location>
            <begin position="40"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="3">
        <location>
            <begin position="261"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP46005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="585" mass="61935" checksum="02DFBF0FCBE51A2B" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIZ9</accession>
    <name>A0A1Q2CIZ9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ribonuclease HII</fullName>
            <shortName evidence="11">RNase HII</shortName>
            <ecNumber evidence="11">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rnhB</name>
        <name evidence="14" type="ORF">RPIT_08555</name>
        <name evidence="15" type="ORF">SAMN05428934_10722</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1T</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1</strain>
        </source>
    </reference>
    <reference evidence="14" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 11 12">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11 12">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11 12">Belongs to the RNase HII family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY96627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08555"/>
    <dbReference type="EnsemblBacteria" id="AQP46091">
        <property type="protein sequence ID" value="AQP46091"/>
        <property type="gene ID" value="RPIT_08555"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY96627">
        <property type="protein sequence ID" value="SDY96627"/>
        <property type="gene ID" value="SAMN05428934_10722"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08555"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07182">
        <property type="entry name" value="RNase_HII_bacteria_HII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00052_B">
        <property type="entry name" value="RNase_HII_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022898">
        <property type="entry name" value="RNase_HII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001352">
        <property type="entry name" value="RNase_HII/HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024567">
        <property type="entry name" value="RNase_HII/HIII_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954">
        <property type="entry name" value="PTHR10954"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954:SF18">
        <property type="entry name" value="PTHR10954:SF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01351">
        <property type="entry name" value="RNase_HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11 12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9 11 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0464">Manganese</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11 12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_HII" evidence="13">
        <location>
            <begin position="24"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="AQP46091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="SDY96627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="213" mass="22935" checksum="0439F08C243E6E2E" modified="2017-04-12" version="1">MIRPGRGAYGYERALARAGLGPVAGADEAGRGACAGPLVAAAVILHPQRPIGGLDDSKALTPQARERLYDEILRRAVAVAWAAVEADECDRLGMHQADLQGLRRAVGRLETAPNYVLTDGFPVDGLGVPGLAMWKGDKVAACVSAASIIAKVTRDRIMQEHDATFPEYGFRVHKGYCTSMHQSALEEHGPSPIHRWCFDNVVRAARSDRVGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ05</accession>
    <name>A0A1Q2CJ05_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PGA_cap domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_08180</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CapA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08180"/>
    <dbReference type="EnsemblBacteria" id="AQP46084">
        <property type="protein sequence ID" value="AQP46084"/>
        <property type="gene ID" value="RPIT_08180"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08180"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07381">
        <property type="entry name" value="MPP_CapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019079">
        <property type="entry name" value="Capsule_synth_CapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09587">
        <property type="entry name" value="PGA_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00854">
        <property type="entry name" value="PGA_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGA_cap" evidence="3">
        <location>
            <begin position="25"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP46084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="363" mass="38350" checksum="40904DF5EF57F745" modified="2017-04-12" version="1">MQSTSPSSSTQEPAPSPTPAPRSATVNVSGDLLWHNTLWTSAAIDARTTGTGSQFDFLPQLEALRPHVEAADLAVCHSEVPFAQEEGPFQNYPLFAAPPHAATAISEVGWDLCTTASNHSLDQGWDGLVHTIDVHESAGILTAGTYRTEAEATEPIIFTTGSGVKIAIVSQTYGLNGIAEPEGKGWSVDLMDSSKAIADAERAREGGADIVGVHMHAGDEYSSEVNQQQRTFAEEVTRSPAVDFVFGQHAHVPQPIDRVNDKWVVYGTGNLIAASGPAKPRTYDGYLAEIVFTEQTDGSFASGSAEFIPTFITPLKSGKPARVLVIADALRDGSAPADQLAASAARTRATVLSLGPAGLTERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ60</accession>
    <name>A0A1Q2CJ60_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_11645</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11645"/>
    <dbReference type="EnsemblBacteria" id="AQP46142">
        <property type="protein sequence ID" value="AQP46142"/>
        <property type="gene ID" value="RPIT_11645"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11645"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="70"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="260"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="66"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP46142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="294" mass="33155" checksum="E606B63D0453AD9F" modified="2017-04-12" version="1">MLRSWQLYVLLLPGIIYLLIFKYWPMYGAQIAFRNYNPADGFTGSPWVGLQHFERFINSFQFRDLLVNTLTINTVGLLVAFPVPIILALIVNQLPSERFKKFIQTVLYSPSFISVVVVVGMIFLLFSPSSGIVNNVLTLSGAEPVFFMGDPEWFRPLYIGSDVWQNAGFSMIIYLAALTAIDPSLHEAAKMDGANKFRRIWHIDIPGILPVVTILFVLAIGNIFNLGFEKVYLMQTPLNLETSEIINTYVYKAGLQQAQFSYSAAIGLFNSVLNLILLVTFNYVAKKANQSSLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ63</accession>
    <name>A0A1Q2CJ63_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Translation initiation factor IF-3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">infC</name>
        <name evidence="9" type="ORF">RPIT_08280</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the IF-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08280"/>
    <dbReference type="EnsemblBacteria" id="AQP46085">
        <property type="protein sequence ID" value="AQP46085"/>
        <property type="gene ID" value="RPIT_08280"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08280"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00080">
        <property type="entry name" value="IF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036788">
        <property type="entry name" value="T_IF-3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036787">
        <property type="entry name" value="T_IF-3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019813">
        <property type="entry name" value="Translation_initiation_fac3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001288">
        <property type="entry name" value="Translation_initiation_fac_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019815">
        <property type="entry name" value="Translation_initiation_fac_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019814">
        <property type="entry name" value="Translation_initiation_fac_3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10938">
        <property type="entry name" value="PTHR10938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00707">
        <property type="entry name" value="IF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05198">
        <property type="entry name" value="IF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54364">
        <property type="entry name" value="SSF54364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55200">
        <property type="entry name" value="SSF55200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00168">
        <property type="entry name" value="infC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00938">
        <property type="entry name" value="IF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IF3_N" evidence="8">
        <location>
            <begin position="7"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="IF3_C" evidence="7">
        <location>
            <begin position="85"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="168"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="170"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP46085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="228" mass="25885" checksum="4BF7B40217C05EA5" modified="2017-04-12" version="1">MSTEPRINDRIRVPEVRLVGPKGEQVGIVRVEDALRLAAENDLDLVEVAPMARPPVAKLMDYGKFKYEAAQKVRDARKNQSNTVTKEMKLRLKIDAHDYETKKGHVVRFLKAGDKVKITIMFRGREQSRPELGMQLLQRLAEDVAEFGFVEAAPKQDGRNMLMVLGPTKKKTEAKVDQQSDRERRMAERAQKQQEEKAAEAELRAQHTTVAAKKKRGPADNMDPDIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ67</accession>
    <name>A0A1Q2CJ67_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Iron complex transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_10480</name>
        <name evidence="9" type="ORF">SAMN05428934_102209</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY54418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10480"/>
    <dbReference type="EnsemblBacteria" id="AQP46123">
        <property type="protein sequence ID" value="AQP46123"/>
        <property type="gene ID" value="RPIT_10480"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY54418">
        <property type="protein sequence ID" value="SDY54418"/>
        <property type="gene ID" value="SAMN05428934_102209"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10480"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP46123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY54418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="316" mass="33382" checksum="FF6D4DA569675D23" modified="2017-04-12" version="1">MPAPNRLAIVGALCLAGALGFLLINAGGNLGFVMELRSKKMLGMIVVGWATGIATVAFQTVTHNRLLTPSIMGLDSMYVFIQSLLAITLGVTFIGQVGVYPMFALNIALMMLAMMGLIAVLFRGKRRSVYVLVLTGLVLGTVLRSASSLIQRMLDPTSFLVLQGNLFASFQTVNPELLWVSGAIVAAGSVWLFRLIPELDVITLGREAAVSLGVRYDSVVRQSLLIGTLLVSVSTALVGPITFLGLIVAALAHQIGGSGRHAVVLPMAGLLGVLLLVGGQAILEQVFGLGTVLSVIIEFVGGIVFIWLVVRKVSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBB5</accession>
    <name>A0A1Q2CBB5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_00020</name>
        <name evidence="7" type="ORF">SAMN05428934_10941</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00020"/>
    <dbReference type="EnsemblBacteria" id="AQP43406">
        <property type="protein sequence ID" value="AQP43406"/>
        <property type="gene ID" value="RPIT_00020"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05379">
        <property type="protein sequence ID" value="SDZ05379"/>
        <property type="gene ID" value="SAMN05428934_10941"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00020"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ05379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="303" mass="30726" checksum="3DC803BD1D7DDF3B" modified="2017-04-12" version="1">MRKLILIGLVGLAAQLVDGGLGMGYGVTSSSLLLLVGLTPALASASVHLAEVGTNVASGLSHWRLGNVDWSLVLRLGVPGAVGAFAGATFLSNLSTVWAGPLMAVILAALGAYILARFAFRPPAVSHARVTPHTSQFLVPLGLLGGFVDATGGGGWGPVSTTSLLSAGKTAPRTVIGSVDTSEFLVSLFASIGFLAALGTSGLDFRIVGVLLVGGLIAAPLAAWLVTKLPARVLGTAVGGLIVVTNLRNVLAALGASPTTQWVALGAVVLLWFTLVGHSLVQHRRQAAAVVAERSETLEPEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBF4</accession>
    <name>A0A1Q2CBF4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ISL3 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_00220</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43439">
        <property type="protein sequence ID" value="AQP43439"/>
        <property type="gene ID" value="RPIT_00220"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00220"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002560">
        <property type="entry name" value="Transposase_DDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032877">
        <property type="entry name" value="Transposase_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029261">
        <property type="entry name" value="Transposase_Znf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01610">
        <property type="entry name" value="DDE_Tnp_ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13542">
        <property type="entry name" value="HTH_Tnp_ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14690">
        <property type="entry name" value="zf-ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-ISL3" evidence="3">
        <location>
            <begin position="23"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_Tnp_ISL3" evidence="2">
        <location>
            <begin position="78"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_ISL3" evidence="1">
        <location>
            <begin position="165"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="414" mass="46590" checksum="8F59E83D66CBC08B" modified="2017-04-12" version="1">MVGVHRDDAGLRVEVESRPPAVMGCPACGVIAHAHGRQRVELIDAPCFTAPVKLRWRKRRWLCPEPMCPVTSFMEQDPDVARPRALLTARATSWAIGQMRRENASVQGMARQLGCTWRTLWRAVKPILETAAADETRFVGVTSLGVDEHIWHHVSTKPVDQGGRGPKEFTGMVDLTRDKDGRVRARLLDLVPGRSGEAYTSWLRDRGDTFRKGVEIATLDPFHGYKNAIDDQLDDVIAVLDAFHVVKLGTAAVDEVRRRVQQDIHGHRGRRDDPLYRIRNLLRAGKEHLTDRQKTRLETAFSVDDRHVEVEVAWHCAQQLRSVYHQSNHADGRRVAEKILASFPSCPIPEIARLGRTLNRWRDALLGYFTTGGANNGGTEAINGLIELARRVARGFRNPGNYRLRMLLIGALRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBF9</accession>
    <name>A0A1Q2CBF9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00230</name>
        <name evidence="2" type="ORF">SAMN05428934_1052</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY83425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43441">
        <property type="protein sequence ID" value="AQP43441"/>
        <property type="gene ID" value="RPIT_00230"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY83425">
        <property type="protein sequence ID" value="SDY83425"/>
        <property type="gene ID" value="SAMN05428934_1052"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00230"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY83425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="132" mass="14807" checksum="3268D823C5B94B99" modified="2017-04-12" version="1">MITPPDELINDLREAVAKNQIAHFLRDPHTQAIRVLVHDETAGRHLADKWPGRLLLVNSQWTVDELTQFDSVIDAFQGHVLTHQGGINLNTMQPYVTLTVDRDTPEVQHLRNAVPSTYLTVRISPGSEPLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBG9</accession>
    <name>A0A1Q2CBG9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Branched-chain amino acid transport protein (AzlD)</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Branched-chain amino acid transporter AzlD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00315</name>
        <name evidence="3" type="ORF">SAMN05428934_10517</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY83831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="RPIT_00315"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY83831"/>
        <property type="gene ID" value="SAMN05428934_10517"/>
    </dbReference>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Brnchd-chn_aa_trnsp_AzlD"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY83831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="102" mass="10621" checksum="5E77D9DE57190D6E" modified="2017-04-12" version="1">MSVWLWILAACLIAFGTKLVGYLLPERWLENPWVLPLSHGVTVGLLASLVATSTFSSGQSLAVDARLVALLAAAAALRVKAPYLVVVIVGAVAAALARLIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBI6</accession>
    <name>A0A1Q2CBI6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcription factor WhiB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00455</name>
        <name evidence="3" type="ORF">SAMN05428934_10545</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY84630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43474">
        <property type="protein sequence ID" value="AQP43474"/>
        <property type="gene ID" value="RPIT_00455"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY84630">
        <property type="protein sequence ID" value="SDY84630"/>
        <property type="gene ID" value="SAMN05428934_10545"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00455"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034768">
        <property type="entry name" value="4FE4S_WBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02467">
        <property type="entry name" value="Whib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51674">
        <property type="entry name" value="4FE4S_WBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S Wbl-type" evidence="1">
        <location>
            <begin position="6"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY84630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="177" mass="18776" checksum="8C395B8853304FBE" modified="2017-04-12" version="1">MTAATPCVVSPNVFLHPLLDDAPPTNRGERREQAMLRTQAAKMCAACPRRGQCLTEAVTKFDVAGFVGGTTKRQRAEIRARLGVSVSPEDLDGFAGVNSGRQFNKHEIHRLRAANPDQPLSVIAAKIGCSVSTVKRHLRRIEEEGGLHTAPAAEPPSIDAVLAAADAVCGSRTDSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBQ9</accession>
    <name>A0A1Q2CBQ9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00855</name>
        <name evidence="3" type="ORF">SAMN05428934_105124</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43546">
        <property type="protein sequence ID" value="AQP43546"/>
        <property type="gene ID" value="RPIT_00855"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86716">
        <property type="protein sequence ID" value="SDY86716"/>
        <property type="gene ID" value="SAMN05428934_105124"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00855"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007403">
        <property type="entry name" value="DUF456"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04306">
        <property type="entry name" value="DUF456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY86716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="163" mass="16688" checksum="F5A14C747744197E" modified="2017-04-12" version="1">MSTDIIAAVAAAALALLGLVGIVFPVLPGSITVAVGALVWAIWGSSTWGWVAFGVAAVLLLIGALSSWLLTGRSLQQRQVPKWPIAVGLVLGIVGMIVLPGLGLPIGFVVGLLLAELYRVRNLRDAVATSWATIKALGLGIIVELLCAMAATAVLAVSIATAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBT2</accession>
    <name>A0A1Q2CBT2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TNase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00930"/>
    <dbReference type="EnsemblBacteria" id="AQP43560">
        <property type="protein sequence ID" value="AQP43560"/>
        <property type="gene ID" value="RPIT_00930"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00930"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016071">
        <property type="entry name" value="Staphylococal_nuclease_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00565">
        <property type="entry name" value="SNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50199">
        <property type="entry name" value="SSF50199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TNase-like" evidence="1">
        <location>
            <begin position="18"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="203" mass="21478" checksum="D97B38D0867B55F6" modified="2017-04-12" version="1">MTFSAVIDGDTVETSQGTVRLIGIDTPERGECGHDEASMAIGLVVSVGEVVTLELPDGQNDRDSYGRLLRYVITESGVDLGQMQMEAGNAIARYDSTDGYPAHPRQDDYHAAQIATAGADGSIITTSCGGAAQESIAPLAAPVPTGEPWWVQYSSCTKLKKNTVGHPTGPFSVDDPAEVEIYNWFQFGTGHHGDGDNDGLACE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBU5</accession>
    <name>A0A1Q2CBU5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_01035</name>
        <name evidence="6" type="ORF">SAMN05428934_105158</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43578">
        <property type="protein sequence ID" value="AQP43578"/>
        <property type="gene ID" value="RPIT_01035"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87649">
        <property type="protein sequence ID" value="SDY87649"/>
        <property type="gene ID" value="SAMN05428934_105158"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01035"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="12"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="158"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY87649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="229" mass="24336" checksum="643060E3C3D32DC5" modified="2017-04-12" version="1">MTHQRQGGTAIRVLLADDQELIRYGLRLVLEAEPDIVVVGEAGDGDEALRAANRLSPDVVLMDVRMPGMGGIEATALITATHPATRVLVLTTYDRDDFAFGALEAGAAGFLLKNTPPAELVAAVRTVVAGDAVVSPRVTARLIEVAVPHLSDGDRRVGEQELSVLSDREREVFVLVGRGLTNSEIARALYLSESTVKAHFGRILAKLGVPNRVQAVIRAYELGVVGPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBY6</accession>
    <name>A0A1Q2CBY6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Predicted dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00900</name>
        <name evidence="4" type="ORF">SAMN05428934_105132</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00900"/>
    <dbReference type="EnsemblBacteria" id="AQP43555">
        <property type="protein sequence ID" value="AQP43555"/>
        <property type="gene ID" value="RPIT_00900"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86939">
        <property type="protein sequence ID" value="SDY86939"/>
        <property type="gene ID" value="SAMN05428934_105132"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00900"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="4"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="142"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY86939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="391" mass="41799" checksum="8602BDF2C5729B46" modified="2017-04-12" version="1">MSIGIAVIGAGMAGKAHAAAYRVAPTLYQPTLPELRFVSVGDVNAPLAEATANRYGFDRHDTDWRAIAEDPDIHVVSVVIANSLHLEVVKGLLDAGKHVLCEKPLADTLESAREMARLAREASSITRVGLTYRRQPGIAAIKNWIDDGTLGRVLHYSGRYWCDYGCNPNGPISWRYKGPMGSGALADVGSHLTYLSEFVVGQNIQTVSGGAFMTAITERPVPLGAVVGHGMTEISDEREPVENDDYATYTALFGDVRGSFEVSRVAAGYPNGLNIEVFCENGAASFHQDTPSQVRLYLHGDDPGTNGYRTVNLGSDHPYVAGGMAMDVSGVGFGQNEGFAYQARAFLEEVAGIPEAESLPRNASFDDGVHNMEILAAVAESAANNGKTVHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC67</accession>
    <name>A0A1Q2CC67_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA-binding response regulator, OmpR family, contains REC and winged-helix (WHTH) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01790</name>
        <name evidence="4" type="ORF">SAMN05428934_108106</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01790"/>
    <dbReference type="EnsemblBacteria" id="AQP43696">
        <property type="protein sequence ID" value="AQP43696"/>
        <property type="gene ID" value="RPIT_01790"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02963">
        <property type="protein sequence ID" value="SDZ02963"/>
        <property type="gene ID" value="SAMN05428934_108106"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01790"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="110"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="1">
        <location>
            <begin position="110"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ02963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="214" mass="23366" checksum="F2D7C94E107C6617" modified="2017-04-12" version="1">MSRIVFVSSTQPPSELTLLSYEMTTVESAADALQEAADVYVIDGRTDLAGARAACQTLSRAEAPVLLLVALAGLAVLSPDWGFSDFVAANSEPAEFDARLRVLLRTNADPDVLVAGPIRVDGAAYSATLDGAPLDLTYTEFELLRYLMQHPGRVLSRETLVSQVWGYDYYGGTRTVDVHVRRLRAKLGQFDHYVGTVRNVGYRFANAREAHRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC71</accession>
    <name>A0A1Q2CC71_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Polyketide cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_01840</name>
        <name evidence="2" type="ORF">SAMN05428934_108116</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ03169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01840"/>
    <dbReference type="EnsemblBacteria" id="AQP43704">
        <property type="protein sequence ID" value="AQP43704"/>
        <property type="gene ID" value="RPIT_01840"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ03169">
        <property type="protein sequence ID" value="SDZ03169"/>
        <property type="gene ID" value="SAMN05428934_108116"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01840"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ03169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="153" mass="16678" checksum="C405EB453CBAF42F" modified="2017-04-12" version="1">MSDNTSVQVSRTINAPADKVFEHLTLPANHVELDGSGFIRSVAHGDRIQAVGDVFTMNMEGDHMGGEYQTDNHVTAYGRNAVVGWATAPAGTEPPGWTWVWELEGEGTGATRVTLTYDWSKVTDKELLKKVSFPLVEESKLEDSLAKLSEALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC78</accession>
    <name>A0A1Q2CC78_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_01890</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01890"/>
    <dbReference type="EnsemblBacteria" id="AQP43712">
        <property type="protein sequence ID" value="AQP43712"/>
        <property type="gene ID" value="RPIT_01890"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01890"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="189"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="75"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="282" mass="31370" checksum="A323BF87C5266FC6" modified="2017-04-12" version="1">MKDGRYRSPFSMVVMFLLALLWAVPTLGLLVISFQTRDSALRGGWWEAIYKPFERTWTFDNYTRVFEMQDMGNAFLNGIAVAVPATIIPIMFAAFAAYAFTFMSFPFKDVLFIIIVAVMVVPIQVAFQPLLNLMGPNGLGISGQYLAVWILHTGFGMPLCIYTLRNYMSSLPYSVVESARIDGCSNFQIFWKLIAPMSTPAIAAFATLQFLWVWNDLLIAKLFLSNDNTTVIVKVQQLLGTQGQGAELVTAGAFISMVLPMIVFFTLQNFLVRGMTAGAVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC86</accession>
    <name>A0A1Q2CC86_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphoribosylaminoimidazole-succinocarboxamide synthase</fullName>
            <ecNumber evidence="8">6.3.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">SAICAR synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">purC</name>
        <name evidence="10" type="ORF">RPIT_01975</name>
        <name evidence="11" type="ORF">SAMN05428934_1169</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:22628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the SAICAR synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.6" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000016">
        <property type="protein sequence ID" value="SDZ20272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01975"/>
    <dbReference type="EnsemblBacteria" id="AQP43728">
        <property type="protein sequence ID" value="AQP43728"/>
        <property type="gene ID" value="RPIT_01975"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ20272">
        <property type="protein sequence ID" value="SDZ20272"/>
        <property type="gene ID" value="SAMN05428934_1169"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01975"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00131"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004639">
        <property type="term" value="F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00137">
        <property type="entry name" value="SAICAR_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028923">
        <property type="entry name" value="SAICAR_synt/ADE2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001636">
        <property type="entry name" value="SAICAR_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018236">
        <property type="entry name" value="SAICAR_synthetase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01259">
        <property type="entry name" value="SAICAR_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00081">
        <property type="entry name" value="purC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01058">
        <property type="entry name" value="SAICAR_SYNTHETASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAICAR_synt" evidence="9">
        <location>
            <begin position="14"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP43728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDZ20272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="291" mass="32379" checksum="634EA91C86F0A1D2" modified="2017-04-12" version="1">MSQFQELVGLPLRHAGKVRELYADDHRILMVATDNISAFDHVLSMLIPDKGAILTQLSLWWFDQLSDLVPNHVLSAEVPPAVAGRALWVEPLEMVEVECVARGYLTGSGWAEYQESRTVCGVALPEGLRDGDKLPEPIFTPAIKARLGEHDENVDFATIVDLHGSALAEELRRLTLAIYTRAAGIAAERGIILADTKFEFGRRPDGTLVLADEVLTPDSSRFWDAALWQPGESLPSFDKQYVRDWLARDSGWDRSSDTPPPALPDDVVAATRERYLEAYRRLTGTDFSPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC98</accession>
    <name>A0A1Q2CC98_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-nitropropane dioxygenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Nitronate monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02055</name>
        <name evidence="3" type="ORF">SAMN05428934_1018</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY22540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02055"/>
    <dbReference type="EnsemblBacteria" id="AQP43743">
        <property type="protein sequence ID" value="AQP43743"/>
        <property type="gene ID" value="RPIT_02055"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY22540">
        <property type="protein sequence ID" value="SDY22540"/>
        <property type="gene ID" value="SAMN05428934_1018"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02055"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NMO" evidence="1">
        <location>
            <begin position="87"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY22540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="306" mass="31440" checksum="6A9499B65892B3F2" modified="2017-04-12" version="1">MPIPAPLKDRLRLPVVAAPMFLVSGPELVVAACRSGVIGSFPALNQRTTAGLDEWLAEIETALSDDDAPYAVNLIVHPTNTRLQDDLAAVVAHRVPVVITSLGAVPELVEAVHGYGGIVLHDVTTLRHARKAAGAGVDGLVLVAAGAGGHAGTLNPFALLASVRPWFDGIIALSGSLSSGSDVAAALAMGADLAYMGTRFLATRESAAPEAYRQQVVAAAASDIVYTPAVSGIPANFLSSSLKAAGVDPAGPPAESEDVKAWRDVWSAGHGVAAIDDVPSVAELVDRLRREYDGAIDRLCGGHASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCA7</accession>
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    </protein>
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    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="511"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1" evidence="2">
        <location>
            <begin position="84"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="560" mass="59874" checksum="DF3BAA4CD5CCF339" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCF0</accession>
    <name>A0A1Q2CCF0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA replication protein DnaC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02295</name>
        <name evidence="3" type="ORF">SAMN05428934_10158</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY24029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02295"/>
    <dbReference type="EnsemblBacteria" id="AQP43789">
        <property type="protein sequence ID" value="AQP43789"/>
        <property type="gene ID" value="RPIT_02295"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY24029">
        <property type="protein sequence ID" value="SDY24029"/>
        <property type="gene ID" value="SAMN05428934_10158"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR002611">
        <property type="entry name" value="IstB_ATP-bd"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="103"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY24029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="256" mass="28079" checksum="D233529CCF29FFFB" modified="2017-04-12" version="1">MTTGKNIAAEIAFLARELKTPVITETFTTLGDQARQAGWSHEEYLAAVLGRQVASRTANGTRMRISAAHFPQVKTMQDFTFDHIPAVTRDVIAHLGTCTFIAKRENVVLLGPPGTGKTHLAIALGIKAAEASYPVLFDSATGWIHRLAQAHAKGSLERELRRLNRYRLLIIDEVGYLPLDAAAAALFFQLVASRYETGSIIVTSNLPFSRWGETLGDDVVAAATIDRLVHHAHVIALDGDSYRTRGHRDSINQQNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCG6</accession>
    <name>A0A1Q2CCG6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02390</name>
        <name evidence="3" type="ORF">SAMN05428934_10176</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY24572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02390"/>
    <dbReference type="EnsemblBacteria" id="AQP43808">
        <property type="protein sequence ID" value="AQP43808"/>
        <property type="gene ID" value="RPIT_02390"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY24572">
        <property type="protein sequence ID" value="SDY24572"/>
        <property type="gene ID" value="SAMN05428934_10176"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02390"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY24572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="310" mass="32005" checksum="B5DC0BF14AACB0A5" modified="2017-04-12" version="1">MGAIVASVLPILLLLVLGWALRAARVLDAVAVDAIKDFVFKVVLPAVLFQAFVSIELRAEYLALVGVVVAVSAALLAAGYAARRAVGWLNPLTPFLATGFAFGMVGIPLFAAAYGLGELPAIGMVGLGNELFIWLVFVPLVQRLTQGSSAGQALRAFATSPVVFSIAAGLLVNVTGLGARLGEAALGAAVLATIEHLAAVAVPLMLIFVGHGTRLSRDGVRQAAPFVAVRVAVLVPLALGLGHVVVDGILGLPPIVEAALFTLLILPPPFILPVLIPRRHQSDLTYATNVLSLHTVVSVGLFIAYVAATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCH3</accession>
    <name>A0A1Q2CCH3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FtsX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_02370</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02370"/>
    <dbReference type="EnsemblBacteria" id="AQP43804">
        <property type="protein sequence ID" value="AQP43804"/>
        <property type="gene ID" value="RPIT_02370"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02370"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="380"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="434"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="476"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="408"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP43804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="515" mass="52745" checksum="A5C956422901C31F" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCU1</accession>
    <name>A0A1Q2CCU1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5 7">30S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsL</name>
        <name evidence="9" type="ORF">RPIT_02950</name>
        <name evidence="10" type="ORF">SAMN05428934_101191</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="1 5 7">With S4 and S5 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5 7">Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY27958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02950"/>
    <dbReference type="EnsemblBacteria" id="AQP43900">
        <property type="protein sequence ID" value="AQP43900"/>
        <property type="gene ID" value="RPIT_02950"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY27958">
        <property type="protein sequence ID" value="SDY27958"/>
        <property type="gene ID" value="SAMN05428934_101191"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02950"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00403_B">
        <property type="entry name" value="Ribosomal_S12_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_S12/S23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_S12_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="PTHR11652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00981">
        <property type="entry name" value="rpsL_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 6 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP43900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY27958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="123" mass="13634" checksum="6551904ED32577FA" modified="2017-04-12" version="1">MPTIQQLVRKGRTDKVSKNKTPALKGSPQRRGVCTRVYTTTPKKPNSALRKVARVRLSSGIEVTAYIPGVGHNLQEHSMVLVRGGRVKDLPGVRYKIIRGSLDTQGVKGRKQARSRYGAKKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD30</accession>
    <name>A0A1Q2CD30_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA replication protein DnaC</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03655</name>
        <name evidence="3" type="ORF">SAMN05428934_101333</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY32333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03655"/>
    <dbReference type="EnsemblBacteria" id="AQP44019">
        <property type="protein sequence ID" value="AQP44019"/>
        <property type="gene ID" value="RPIT_03655"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY32333">
        <property type="protein sequence ID" value="SDY32333"/>
        <property type="gene ID" value="SAMN05428934_101333"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03655"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028350">
        <property type="entry name" value="DNAC/ATP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002611">
        <property type="entry name" value="IstB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01695">
        <property type="entry name" value="IstB_IS21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003073">
        <property type="entry name" value="DNAC_TnpB_IstB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="107"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY32333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="260" mass="28072" checksum="9F2213254090CCF1" modified="2017-04-12" version="1">MNPTTMHPAPPLPEDLTGLLRRMRLPYLRAAAPEVLATAKAQRWDPAEVLRVLLTEEIRGRDEATKTMRRKAAGLPAGKTFDSWREHDSSIPAPTQSALAGLEWISRAENLAITGPSGTGKTHFVEALAHNVIDAGMRVSWFTLESLTAAITRAGADNSVNKVIARITRAELIVVDDIGMLPSGQAAAEAFYRLVDATYERRSLAVTSNLHPAGFDTIMPKTLATAAVDRLLHHAHVIVTEGTSLRLTEATAGRGAVPLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD34</accession>
    <name>A0A1Q2CD34_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Alpha-E domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03475"/>
    <dbReference type="EnsemblBacteria" id="AQP43990">
        <property type="protein sequence ID" value="AQP43990"/>
        <property type="gene ID" value="RPIT_03475"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03475"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025841">
        <property type="entry name" value="CP_ATPgrasp_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007296">
        <property type="entry name" value="DUF403"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04168">
        <property type="entry name" value="Alpha-E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14403">
        <property type="entry name" value="CP_ATPgrasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-E" evidence="1">
        <location>
            <begin position="481"/>
            <end position="783"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="803" mass="86347" checksum="D6106801D2F3E776" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD37</accession>
    <name>A0A1Q2CD37_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_03325</name>
        <name evidence="7" type="ORF">SAMN05428934_101266</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43965">
        <property type="protein sequence ID" value="AQP43965"/>
        <property type="gene ID" value="RPIT_03325"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30303">
        <property type="protein sequence ID" value="SDY30303"/>
        <property type="gene ID" value="SAMN05428934_101266"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03325"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY30303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="246" mass="26161" checksum="EA15B048912E0998" modified="2017-04-12" version="1">MDLTITALVVLIAAALLIGIAKTALPGAATLSVAAFAAILPARESTAALLVLLLVGDIVAIWSYRRDVDWRILARLLPTVVGGMIVGWLFLASADDPLVRRGIGAILLTLTALTLTLRRRGHLTAERALTNPWIRGVFGSLGGFTSMAANAGGPVMTLYFVAARFDVLRFLGTQAWFFFVLNAVKLPFSIGLGLLQPSMLPLLGALAPVVLAGAFAGRVWARRIDKTLFDRVVIGLTIASSLYLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD41</accession>
    <name>A0A1Q2CD41_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Carboxylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_03775</name>
        <name evidence="6" type="ORF">SAMN05428934_101357</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY32996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03775"/>
    <dbReference type="EnsemblBacteria" id="AQP44042">
        <property type="protein sequence ID" value="AQP44042"/>
        <property type="gene ID" value="RPIT_03775"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY32996">
        <property type="protein sequence ID" value="SDY32996"/>
        <property type="gene ID" value="SAMN05428934_101357"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03775"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012354">
        <property type="entry name" value="Esterase_lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017388">
        <property type="entry name" value="Esterase_lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="4">
        <location>
            <begin position="27"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR017388-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR017388-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR017388-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY32996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="264" mass="28716" checksum="C4F3207D981EC76C" modified="2017-04-12" version="1">MRVFPAPSPTVWPEARPLRLGDGDTGIVISHGFTGSVASVAPWARGLAEPSGEWPGARVVAPRLPGHGTSWQDLARTRWWDWYGAVEDAYLGLAAECSAVFVAGLSMGGALALRLASLHPVDGVLLVNPAVASRDRRIPVAARLRNVLPPQRGISSDIADPAQREPGYPRFSVKSLGTMDDLWRDTRPRLPRVSAPTLLLRSAQDHVVDDLSGELIRAAVPRVEERVLTRSYHVATMDYDRQRIIDESRRFILDIGAAGPRGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD64</accession>
    <name>A0A1Q2CD64_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Macrolide ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Putative ABC transport system ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_03870</name>
        <name evidence="6" type="ORF">SAMN05428934_101377</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY33518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03870"/>
    <dbReference type="EnsemblBacteria" id="AQP44058">
        <property type="protein sequence ID" value="AQP44058"/>
        <property type="gene ID" value="RPIT_03870"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY33518">
        <property type="protein sequence ID" value="SDY33518"/>
        <property type="gene ID" value="SAMN05428934_101377"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03870"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY33518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="222" mass="23464" checksum="27027A597E2352A2" modified="2017-04-12" version="1">MNVLEFRCVAKVFAGPPQVQALQPCSFAISSGELVTITGPSGSGKSTLLNLAGLLDCPSQGHVLVNGIDTSELREQERTAIRGQTIGFVFQAFHLMARRTVLENVSLAGLYRHQDAATRMRGASAAIKLVGLADRSESHAGVLSGGERQRVAIARAMAVQPTVLLCDEPTGNLDSVNSALIVDLLLKLSRSGTTVILITHNAAIAEIGTRRMTLLDGVVHDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD84</accession>
    <name>A0A1Q2CD84_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 7">Transcriptional regulator MraZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mraZ</name>
        <name evidence="10" type="ORF">RPIT_03985</name>
        <name evidence="11" type="ORF">SAMN05428934_101400</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Forms oligomers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
            <location evidence="7">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MraZ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY34076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03985"/>
    <dbReference type="EnsemblBacteria" id="AQP44078">
        <property type="protein sequence ID" value="AQP44078"/>
        <property type="gene ID" value="RPIT_03985"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY34076">
        <property type="protein sequence ID" value="SDY34076"/>
        <property type="gene ID" value="SAMN05428934_101400"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03985"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16321">
        <property type="entry name" value="MraZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16320">
        <property type="entry name" value="MraZ_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01008">
        <property type="entry name" value="MraZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003444">
        <property type="entry name" value="MraZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035644">
        <property type="entry name" value="MraZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020603">
        <property type="entry name" value="MraZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035642">
        <property type="entry name" value="MraZ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038619">
        <property type="entry name" value="MraZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34701">
        <property type="entry name" value="PTHR34701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02381">
        <property type="entry name" value="MraZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00242">
        <property type="entry name" value="TIGR00242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51740">
        <property type="entry name" value="SPOVT_ABRB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="10" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="9">
        <location>
            <begin position="5"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="SpoVT-AbrB" evidence="9">
        <location>
            <begin position="76"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY34076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="145" mass="16133" checksum="0278581FD97EC465" modified="2017-04-12" version="1">MFLGTYTPKLDEKGRLILPARFRDDLEEGLVVTRTQERALAVYPKATFEALLRPVLNAPSTLKQVRDYQRMLTAGASFEIPDRQGRVTIPPLLRTYAGLDRDVVVIGAGDRAEIWDASTWLTYSDANEDGFAEMDSAVTALLGDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDB7</accession>
    <name>A0A1Q2CDB7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">YggT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_04055</name>
        <name evidence="4" type="ORF">SAMN05428934_101414</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YggT family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY34491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04055"/>
    <dbReference type="EnsemblBacteria" id="AQP44087">
        <property type="protein sequence ID" value="AQP44087"/>
        <property type="gene ID" value="RPIT_04055"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY34491">
        <property type="protein sequence ID" value="SDY34491"/>
        <property type="gene ID" value="SAMN05428934_101414"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04055"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003425">
        <property type="entry name" value="CCB3/YggT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02325">
        <property type="entry name" value="YGGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY34491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="94" mass="10952" checksum="936690FA10B62848" modified="2017-04-12" version="1">MVAYLLWWLLNIYIWLLLARVILSWVPMFAPSWTPKGPILVIVEFVYSLTDPPVKALRRVIKPVRMGNAQLDLSVLVLFVLLQVLQSMLRFLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDG9</accession>
    <name>A0A1Q2CDG9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_04390</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EamA transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04390"/>
    <dbReference type="EnsemblBacteria" id="AQP44146">
        <property type="protein sequence ID" value="AQP44146"/>
        <property type="gene ID" value="RPIT_04390"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04390"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004626">
        <property type="entry name" value="RarD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911:SF114">
        <property type="entry name" value="PTHR22911:SF114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00688">
        <property type="entry name" value="rarD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="9">
        <location>
            <begin position="167"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="325" mass="34639" checksum="F945D152E4C09AEC" modified="2017-04-12" version="1">MSWQQTSAQRYAHPTMIQPARAGLLYGLAAYGLWGLFPLFFLLFARSGALEVVAHRALWSLVFCALLLTVLRQWDSVRVVLADRRTTAALVAAGFLIVVNWSTYVFAVLTDRTLETALGYFINPLAVAALGIFVLGERLRRLQWVAMGLGGASVAVMVGGYGEVPWTALLLATSFGLYSLVKKVAGRSVGALPGLALETAAVAPLAVAYLAFLGATGASSATLADGYGLLLVSTGIVTAVPLLLFAAAARRVSMITIAILQYLAPIGQFLLGWLVLHEPMPPVRWAGFALVWAGVLVFVADSLLTSRRAASARRRLRREGGVGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDM2</accession>
    <name>A0A1Q2CDM2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hydroxymethylbilane synthase</fullName>
            <ecNumber evidence="5">2.5.1.61</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_04745</name>
        <name evidence="12" type="ORF">SAMN05428934_101558</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + 4 porphobilinogen = hydroxymethylbilane + 4 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="EC" id="2.5.1.61"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>dipyrromethane</name>
            <dbReference type="ChEBI" id="CHEBI:60342"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HMBS family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.61" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY38331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04745"/>
    <dbReference type="EnsemblBacteria" id="AQP44209">
        <property type="protein sequence ID" value="AQP44209"/>
        <property type="gene ID" value="RPIT_04745"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY38331">
        <property type="protein sequence ID" value="SDY38331"/>
        <property type="gene ID" value="SAMN05428934_101558"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04745"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004418">
        <property type="term" value="F:hydroxymethylbilane synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06578">
        <property type="entry name" value="HemD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003754">
        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000860">
        <property type="entry name" value="HemC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022417">
        <property type="entry name" value="Porphobilin_deaminase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022418">
        <property type="entry name" value="Porphobilinogen_deaminase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036803">
        <property type="entry name" value="Porphobilinogen_deaminase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557">
        <property type="entry name" value="PTHR11557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01379">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03900">
        <property type="entry name" value="Porphobil_deamC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00151">
        <property type="entry name" value="PORPHBDMNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54782">
        <property type="entry name" value="SSF54782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="SSF69618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00212">
        <property type="entry name" value="hemC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Porphobil_deam" evidence="8">
        <location>
            <begin position="3"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Porphobil_deamC" evidence="10">
        <location>
            <begin position="217"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="HEM4" evidence="9">
        <location>
            <begin position="334"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY38331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="555" mass="60035" checksum="80EEBB4A64CE68F3" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDN5</accession>
    <name>A0A1Q2CDN5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_04875</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04875"/>
    <dbReference type="EnsemblBacteria" id="AQP44228">
        <property type="protein sequence ID" value="AQP44228"/>
        <property type="gene ID" value="RPIT_04875"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04875"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="830" mass="92265" checksum="79AB62C12CB6B727" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDP9</accession>
    <name>A0A1Q2CDP9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongation factor 4</fullName>
            <shortName evidence="5">EF-4</shortName>
            <ecNumber evidence="5">3.6.5.n1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ribosomal back-translocase LepA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lepA</name>
        <name evidence="7" type="ORF">RPIT_04865</name>
        <name evidence="8" type="ORF">SAMN05428934_101581</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.n1" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY38887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04865"/>
    <dbReference type="EnsemblBacteria" id="AQP44226">
        <property type="protein sequence ID" value="AQP44226"/>
        <property type="gene ID" value="RPIT_04865"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY38887">
        <property type="protein sequence ID" value="SDY38887"/>
        <property type="gene ID" value="SAMN05428934_101581"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04865"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="entry name" value="lepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00071">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006297">
        <property type="entry name" value="EF-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038363">
        <property type="entry name" value="LepA_C_sf"/>
    </dbReference>
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        <property type="entry name" value="LepA_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035654">
        <property type="entry name" value="LepA_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512">
        <property type="entry name" value="PTHR43512"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06421">
        <property type="entry name" value="LepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01393">
        <property type="entry name" value="lepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="6">
        <location>
            <begin position="12"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="24"/>
            <end position="29"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="140"/>
            <end position="143"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY38887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="609" mass="67450" checksum="7BF1598D26E13E7E" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDR9</accession>
    <name>A0A1Q2CDR9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fructokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_04820</name>
        <name evidence="5" type="ORF">SAMN05428934_101572</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP44220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY38680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04820"/>
    <dbReference type="EnsemblBacteria" id="AQP44220">
        <property type="protein sequence ID" value="AQP44220"/>
        <property type="gene ID" value="RPIT_04820"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY38680">
        <property type="protein sequence ID" value="SDY38680"/>
        <property type="gene ID" value="SAMN05428934_101572"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
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        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="4"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY38680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="306" mass="32172" checksum="5709E157320948CC" modified="2017-04-12" version="1">MRFVVCGEALIDLMPEESISPAESRWIARSGGGPLNTSAALAKLGRDSHFLGRLSNDAFGRQLRSHLEASGVQTDISVSTDDPTSVAVVSLDERGHASYTFHFEGTSNFNWKADEFPVLDSDDWLHFGSIGAVIGPGAKRVLDFVRSTQAAVSFDINVRPSCLPDRAAYFALVTDLMTAVGGHAGIVKASDEDIAWLVDDDTDPLGYAEAWAAEFGLSLFIVTLGADGVAAVKPDGRVIRVPGNRVQVVDTVGAGDTFMAGFLSAFAEDPDNVAAALARGAAAAAIVCTRKGAQPPSAAEVDAFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDT1</accession>
    <name>A0A1Q2CDT1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphatidylglycerophosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_04885</name>
        <name evidence="4" type="ORF">SAMN05428934_101585</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY38997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04885"/>
    <dbReference type="EnsemblBacteria" id="AQP44230">
        <property type="protein sequence ID" value="AQP44230"/>
        <property type="gene ID" value="RPIT_04885"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY38997">
        <property type="protein sequence ID" value="SDY38997"/>
        <property type="gene ID" value="SAMN05428934_101585"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04885"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY38997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="189" mass="20386" checksum="0E076F00B7589C88" modified="2017-04-12" version="1">MGKPLPDARRPGLRLTPADRVTLTRAALGLGCAVLVALTYAGVLPMRSWPLFLLAVPAAVLDAVDGPVARRTGTVTERGSRWDMEVDSAFLLVLSVALFPLAPWVAVIGLARYLFWVGGVLRPAWRRPLAFRQSRRIIAAYQAVAMVVALAPFLPLWVGQGMTALAVGLLLFSFGRDIATQERTAAGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDX0</accession>
    <name>A0A1Q2CDX0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44291">
        <property type="protein sequence ID" value="AQP44291"/>
        <property type="gene ID" value="RPIT_05240"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05240"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010224709" evidence="2">
        <location>
            <begin position="19"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="226" mass="25399" checksum="D112BBBDD8B2C454" modified="2017-04-12" version="1">MLIVVIALIVIVAIVAGAKEKQVADRQRAEELRSKATQEEHLLGKRRERADELGSQAEAARSAALLEAERAERLREEAEAAEERAAYATEDAEVLITEADRSHADYERAEKEHDEMIREADRRDPDVRTDRDGNRILGEDDHRGVDPDGDGLLDRDPDEDVRLRDAGRPIDDTRDAGLHRDDHADTDVDLGSSDLDDDGPAYDDQGRRLDPYGNPVEDYPDDDRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE98</accession>
    <name>A0A1Q2CE98_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carbamoyl-phosphate synthase small chain</fullName>
            <ecNumber evidence="2">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Carbamoyl-phosphate synthetase glutamine chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">carA</name>
        <name evidence="4" type="ORF">RPIT_06185</name>
        <name evidence="5" type="ORF">SAMN05428934_103182</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the CarA family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY69770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06185"/>
    <dbReference type="EnsemblBacteria" id="AQP44452">
        <property type="protein sequence ID" value="AQP44452"/>
        <property type="gene ID" value="RPIT_06185"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY69770">
        <property type="protein sequence ID" value="SDY69770"/>
        <property type="gene ID" value="SAMN05428934_103182"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06185"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00171"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01744">
        <property type="entry name" value="GATase1_CPSase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01209">
        <property type="entry name" value="CPSase_S_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006274">
        <property type="entry name" value="CarbamoylP_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002474">
        <property type="entry name" value="CarbamoylP_synth_ssu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036480">
        <property type="entry name" value="CarbP_synth_ssu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035686">
        <property type="entry name" value="CPSase_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00988">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01097">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52021">
        <property type="entry name" value="SSF52021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01368">
        <property type="entry name" value="CPSaseIIsmall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CPSase_sm_chain" evidence="3">
        <location>
            <begin position="4"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="CPSase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="348"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY69770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="375" mass="40489" checksum="FE79580085371FDF" modified="2017-04-12" version="1">MSSLPAILVLEDGRVFRGRSFGAAGETFGELVFSTGMSGYQETLTDPSYRGQVVLMTAPHIGNTGWNDEDDESGRIWVQGLIVRDPAPRPSNWRSRRSLDEELARQDVVGISDIDTRALTRHVRDRGVMRVGISTETQDPALLLARVLEQPTMAGADLVGDVTTDSHYLVPAVGQRRATVVAVDLGIKSMTPVQLAARGLDVHVVPAHTTFEQIKGYAPDGVFFSNGPGDPASATGPIAVLEEVLASGLPYFGICFGNQLFGRALGLDTYKLKFGHRGINQPVIDRTTGKVEITAHNHGFAVDAPLDRATSTRFGEVTVSHVCLNDDVVEGLELHRDGRLLGFSVQYHPEAAAGPHDANYLFDRFADMLSAGKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEP5</accession>
    <name>A0A1Q2CEP5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_06915</name>
        <name evidence="11" type="ORF">SAMN05428934_11062</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06915"/>
    <dbReference type="EnsemblBacteria" id="AQP44576">
        <property type="protein sequence ID" value="AQP44576"/>
        <property type="gene ID" value="RPIT_06915"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09356">
        <property type="protein sequence ID" value="SDZ09356"/>
        <property type="gene ID" value="SAMN05428934_11062"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06915"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="UVRD_HELICASE_CTER"/>
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    </dbReference>
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    <keyword evidence="6 11" id="KW-0347">Helicase</keyword>
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            <end position="529"/>
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        <source>
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        </source>
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            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP44576.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDZ09356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="672" mass="73241" checksum="0544EA70CB4E46E2" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
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    <name>A0A1Q2CEQ7_9ACTN</name>
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        <name evidence="4" type="ORF">SAMN05428934_11050</name>
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        <name type="scientific">Tessaracoccus flavus</name>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
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            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3" key="3">
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                <person name="Peterson S.W."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ09067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="291" mass="30149" checksum="769BD1D07620E20C" modified="2017-04-12" version="1">MQERTTPLIVVGVDGSEDGLRAVRFGAGAAQLIDADLLLVNAVDDTLMAGAWGVVYDPEVLQSAGISANEEAKAVALESGLPDHRLKTEVVMGSPGGVMARLSEVADLIVVGRRAASGLERMFVGSTSVAVVANASCPVVVISAAAHPDRVGDKGVVGVGLQTDPGAEITLEEGFRQAERLGGRLEIVHAVQPPVGIFARKLSPTQLDEQVRFAKGGIEAIAAAVSERHPGVPYEVFVTVDSPINELVSRSAGYDLLVVGVGESGIPGFNLGGLMRGLMAHAECPLFITRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CER2</accession>
    <name>A0A1Q2CER2_9ACTN</name>
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        <name evidence="2" type="ORF">RPIT_06995</name>
        <name evidence="3" type="ORF">SAMN05428934_11046</name>
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
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            <strain evidence="2 4">RP1T</strain>
        </source>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
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                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="AQP44591"/>
        <property type="gene ID" value="RPIT_06995"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
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            <begin position="96"/>
            <end position="119"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ08979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="161" mass="17775" checksum="1EA5CC04C6201E6B" modified="2017-04-12" version="1">MFDPTSWEAPYAVVVIALFFIVMARANATYWLGRGITRGAERTRVRRLLESRHYATATRWLNRWGPPAVSVSFLTIGIQTMVNLAAGVTRMPLRRYLPAVTVGCIMWAFIYATIGFAGFVGIQRLWATSPATVLVLGAVLVAGVTWSVLRREQATPASSNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEY1</accession>
    <name>A0A1Q2CEY1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_07555</name>
        <name evidence="4" type="ORF">SAMN05428934_1243</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000024">
        <property type="protein sequence ID" value="SDZ23362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07555"/>
    <dbReference type="EnsemblBacteria" id="AQP44679">
        <property type="protein sequence ID" value="AQP44679"/>
        <property type="gene ID" value="RPIT_07555"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ23362">
        <property type="protein sequence ID" value="SDZ23362"/>
        <property type="gene ID" value="SAMN05428934_1243"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07555"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="231"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ23362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="344" mass="35900" checksum="88096CBB65D07511" modified="2017-04-12" version="1">MVDPLRMDKAKESLGKAKEGLGKAKEGLGKAADSTGRFARDKSEQLVERTGDLRDAAMETVEELTGKKPDPYVEAIAEYNGAFTQMNDKGSSLLRQRERSTDLIELVELLVNSIANTPKSFDADFEEVEYHKAHFVEATEFARKDLEAARQSAAGAGAGFAAGAAVASMAPTAAMWVATTFGAASTGTAISTLSGAAATNAALAWLGGGALAAGGGGTAAGSALLALAGPIGWTIAGATLLVSITLFARKKFQNRDEKQAAVTAVKQNTALVKGMDTQIDDILGRTTSVREQLMGSYGQALEFFRADFLALSAAQRSQLAALVNNTKACAALLSQRVEQDSQDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF95</accession>
    <name>A0A1Q2CF95_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Predicted arabinose efflux permease, MFS family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_08230</name>
        <name evidence="8" type="ORF">SAMN05428934_11529</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44786">
        <property type="protein sequence ID" value="AQP44786"/>
        <property type="gene ID" value="RPIT_08230"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19594">
        <property type="protein sequence ID" value="SDZ19594"/>
        <property type="gene ID" value="SAMN05428934_11529"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08230"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="36"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="266"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="296"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="326"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="377"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ19594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="443" mass="45491" checksum="70B142278D743305" modified="2017-04-12" version="1">MKSRAVLRSLVGPVYAPTLAQSMGMMATMPVIPLIALSLGFSVPAAAALTMISGVVGVLGPIPLGLAMTIVGERRAMIATGSVVTLTQTGAFLIARDGVADGPTLGHQLGFVATLLVSSVAREVWVIGRQAYLGAALPPELRARGMSTFGGMMRIGQVLGPLLGAGIIALGGEAWVLALDAAAMAVATVLVAVWMVPGEARKNRRQVPGGLARLPVEHSPHDPRRTAGVTMIMVGLAIVPLVMARVGRPLIVPLLGAMLGLAGDEISLIFAVAAVVEIAMFVPAGSLMDRYGRTAVIVPCLFFSGAGYGLLVLLTATLAGGSRSGALIALTASAALIAFGNGFGAGALMTLGIDLSPEANRTRHLARWNTITGSGRLLTPALVSLVTLAWPITAAGAVIGALCWAGALWAVHLLPQVTPTPPHGVFSDGFRTDRGGRWRRSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFA6</accession>
    <name>A0A1Q2CFA6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Tyrosyl-tRNA synthetase</fullName>
            <shortName evidence="7">TyrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tyrS</name>
        <name evidence="9" type="ORF">RPIT_08185</name>
        <name evidence="10" type="ORF">SAMN05428934_11538</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-tyrosyl-tRNA(Tyr)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08185"/>
    <dbReference type="EnsemblBacteria" id="AQP44777">
        <property type="protein sequence ID" value="AQP44777"/>
        <property type="gene ID" value="RPIT_08185"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19796">
        <property type="protein sequence ID" value="SDZ19796"/>
        <property type="gene ID" value="SAMN05428934_11538"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08185"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00805">
        <property type="entry name" value="TyrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02006">
        <property type="entry name" value="Tyr_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002307">
        <property type="entry name" value="Tyr-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024088">
        <property type="entry name" value="Tyr-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024107">
        <property type="entry name" value="Tyr-tRNA-ligase_bac_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766">
        <property type="entry name" value="PTHR11766"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01040">
        <property type="entry name" value="TRNASYNTHTYR"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00234">
        <property type="entry name" value="tyrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="7">
        <location>
            <begin position="228"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ19796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="416" mass="45742" checksum="616C4E8F4908A335" modified="2017-04-12" version="1">MNALLDDLRWRGLIAHSTDPDALAAHLDAGSVKFYIGFDPTARSVHTGNLVQALLARRLQEAGHQPFMLVGGATGLIGDPKESGERVMNSADVVAEWVERIRAQVGRYVSFEGANAATMVNNYDWTSTMSVLDFLRDVGKHFPVNRMLARDVVARRLEAGISYTEFSYVLLQSMDFRELYRRHGVTMQTGGSDQWGNITAGVELIRRSDQGKAHAMATPLLTKADGTKFGKTESGTVWLDPDLTSPYAFHQFFLNAEDAKVIDYLKVFSFRTREEIEELEKATIEAPFRREAQRALADDVTDIVHGVDERRGAVAAAAALFGRGELGELDAPTLERVLREVGGRKVEPGLGVVEAMVEAGLVESKGAARRAISEGGAYLNNDKVTDPELQLNPELLLHGRFAVLRRGRKTVGGVYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFD5</accession>
    <name>A0A1Q2CFD5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Energy-coupling factor transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_08510</name>
        <name evidence="7" type="ORF">SAMN05428934_10713</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY96404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08510"/>
    <dbReference type="EnsemblBacteria" id="AQP44829">
        <property type="protein sequence ID" value="AQP44829"/>
        <property type="gene ID" value="RPIT_08510"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY96404">
        <property type="protein sequence ID" value="SDY96404"/>
        <property type="gene ID" value="SAMN05428934_10713"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08510"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003339">
        <property type="entry name" value="ABC/ECF_trnsptr_transmembrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02361">
        <property type="entry name" value="CbiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="265"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="311"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="342"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY96404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="375" mass="40027" checksum="C74A2E4B21B9D786" modified="2017-04-12" version="1">MRRYFLPRSIHPFAWWGWALALAAAASNTTNPLLLAGVIAVAALVTISRRDDNPWARSFKLYLILAVFIVVMRVAFRIFFGGGDGPTILFTLPQVPLPTWVRGIRLLGPVSLESLLSGLYDGARLATIVVCIGAANSLANPKKLLASLPGALYELGTVMVVAVSALPQLGESAQRVVRARKLRRSPAGSKRRDKLRAVETIIVPVLSDALERSLALAASMDVRGYGRSGTGRRLHRGLSLWLGVISIMLLATWSFRFLAGSADRSVLGVGILSTSLLVAGLASAMAALHFAGRTVRRTQYRPIRWGIAETLVVVTGVTCAAIVSLVAASADAVVLFPSISPFTWPTLTPLLLLALAAASLPAFLTPPPDLWKAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFG1</accession>
    <name>A0A1Q2CFG1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted Zn-dependent protease, minimal metalloprotease (MMP)-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_08605</name>
        <name evidence="2" type="ORF">SAMN05428934_10732</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY96873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08605"/>
    <dbReference type="EnsemblBacteria" id="AQP44843">
        <property type="protein sequence ID" value="AQP44843"/>
        <property type="gene ID" value="RPIT_08605"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY96873">
        <property type="protein sequence ID" value="SDY96873"/>
        <property type="gene ID" value="SAMN05428934_10732"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08605"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010428">
        <property type="entry name" value="Zincin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038555">
        <property type="entry name" value="Zincin_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06262">
        <property type="entry name" value="Zincin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY96873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="114" mass="12932" checksum="597E6DE569E945C3" modified="2017-04-12" version="1">MDISDDDFEALVEEALDALPEQLVTGLDNLIFVVEDEPEDGSDTLGWYEGTALTERDMYGYGQLPDRVVLFSGPLSRMCQTEDELFEEIWVTLLHELGHYHGIEEEALHELGWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFH0</accession>
    <name>A0A1Q2CFH0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Succinate dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">Succinate dehydrogenase subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_08570</name>
        <name evidence="10" type="ORF">SAMN05428934_10725</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY96705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08570"/>
    <dbReference type="EnsemblBacteria" id="AQP44837">
        <property type="protein sequence ID" value="AQP44837"/>
        <property type="gene ID" value="RPIT_08570"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY96705">
        <property type="protein sequence ID" value="SDY96705"/>
        <property type="gene ID" value="SAMN05428934_10725"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08570"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="7">
        <location>
            <begin position="3"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="152"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY96705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="253" mass="27245" checksum="D49ACC51877DEB61" modified="2017-04-12" version="1">MKLKLRIWRQAGANAAGRMVEYDLDGVSEDMSFLEMLDLLNENLTNRNEEPVAFDHDCREGICGMCGVVINGVAHGAPEGVRTTTCQLHMRSFQDGATIDIEPWRAGSFPVIKDLAVDRTAFDRIIQAGGFISSNTGSAPDAHATPAPKREADVAFDNATCIGCGACVAACPNSSAMLFTAAKITHLAMLPQGQPERYRRVKSMVAQHDEEGFGNCTNIGECAAVCPKGIPLESISQLNRDLVKSLFKADGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFM0</accession>
    <name>A0A1Q2CFM0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Oligoribonuclease</fullName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">orn</name>
        <name evidence="3" type="ORF">RPIT_09060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">3'-to-5' exoribonuclease specific for small oligoribonucleotides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the oligoribonuclease family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09060"/>
    <dbReference type="EnsemblBacteria" id="AQP44922">
        <property type="protein sequence ID" value="AQP44922"/>
        <property type="gene ID" value="RPIT_09060"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09060"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06135">
        <property type="entry name" value="Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00045">
        <property type="entry name" value="Oligoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022894">
        <property type="entry name" value="Oligoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11046">
        <property type="entry name" value="PTHR11046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="2">
        <location>
            <begin position="4"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="211" mass="23249" checksum="5E791150357C0751" modified="2017-04-12" version="1">MSENLVWIDCEMTGLDLGADALIELAVLVTDGDLNVLGDGVDILIRPSDEQLAQMGDFVRDMHTKSGLLDELATGTTLQDAEEQALAYIREYVPISRKAPLAGNTIGTDRMFLARDMPELEQWMHYRNVDVSSIKELARRWAPKVLYAAPAKAGNHRALADIQESIEELRYYRDALFVATPPSSSELRSIAARHRGSLTGTADPGPISQPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFM3</accession>
    <name>A0A1Q2CFM3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2 3">L-ribulose-5-phosphate 4-epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08980</name>
        <name evidence="3" type="ORF">SAMN05428934_107109</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08980"/>
    <dbReference type="EnsemblBacteria" id="AQP44908">
        <property type="protein sequence ID" value="AQP44908"/>
        <property type="gene ID" value="RPIT_08980"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98423">
        <property type="protein sequence ID" value="SDY98423"/>
        <property type="gene ID" value="SAMN05428934_107109"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08980"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldolase_II" evidence="1">
        <location>
            <begin position="21"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY98423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="237" mass="25661" checksum="6E1531826F605C07" modified="2017-04-12" version="1">MTIVLTELSDQQQQSVAATREKVAKLHEELPRNELVVWTAGNVSERVPGTELFVIKPSGVRYDELSADVMVVCTLDGQKIVDGTPDRLSPSSDTAAHAYVYSNMPEVGGVVHTHSTYATAWAARREPIPCVLTMMADEFGGDVPIGPFALIGDDSIGRGIVETLRESRSPAVLMANHGPFTIGKDATAAVKAAVMVEEVARTVHISRQLGEPLRIEQSDIDSLYARYQNVYGQPGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFN3</accession>
    <name>A0A1Q2CFN3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09135</name>
        <name evidence="3" type="ORF">SAMN05428934_107140</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY99033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44932">
        <property type="protein sequence ID" value="AQP44932"/>
        <property type="gene ID" value="RPIT_09135"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY99033">
        <property type="protein sequence ID" value="SDY99033"/>
        <property type="gene ID" value="SAMN05428934_107140"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09135"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018691">
        <property type="entry name" value="DUF2188"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09954">
        <property type="entry name" value="DUF2188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY99033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="79" mass="8429" checksum="73A465029D3846E1" modified="2017-04-12" version="1">MTGPNKRVVQRRSDGDWEVRKPGADRASVVTSTQAEGIQRARTILGNDGGGELQVRSLKGTIRAQDTIAPGNDPRSSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFQ1</accession>
    <name>A0A1Q2CFQ1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44952">
        <property type="protein sequence ID" value="AQP44952"/>
        <property type="gene ID" value="RPIT_09265"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09265"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="65" mass="7037" checksum="50FDE6BEFDB228D9" modified="2017-04-12" version="1">MELGPLFPQEGFLIGGLLFYLVTITVTASVAYLVIRAAVRKGVLEALTQHQKTLRAGESPETSPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFQ9</accession>
    <name>A0A1Q2CFQ9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS1380 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09245</name>
        <name evidence="3" type="ORF">RPIT_09260</name>
        <name evidence="4" type="ORF">RPIT_14030</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09245"/>
    <dbReference type="EnsemblBacteria" id="AQP44948">
        <property type="protein sequence ID" value="AQP44948"/>
        <property type="gene ID" value="RPIT_09245"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44951">
        <property type="protein sequence ID" value="AQP44951"/>
        <property type="gene ID" value="RPIT_09260"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45781">
        <property type="protein sequence ID" value="AQP45781"/>
        <property type="gene ID" value="RPIT_14030"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09245"/>
    <dbReference type="KEGG" id="tfl:RPIT_09260"/>
    <dbReference type="KEGG" id="tfl:RPIT_14030"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13701">
        <property type="entry name" value="DDE_Tnp_1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="1">
        <location>
            <begin position="10"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="463" mass="50425" checksum="E3DB7654F5BDE335" modified="2017-04-12" version="1">MKRTSWSTGMSVTGDGGAVIAHAGSIGLRMLAENTGLTGALSTAMARRSFIPSVHDRGQVLTDVAVMLADGGEAISDIDVLRHQGQVLGPVASAPTVWRALDEVTDARRRKIQAARARVRRHVWAQLTAAGGVPASKVAGTDLGETIVLDVDATIVVTHSEKELASPTFKRTFGYHPIGVWCDNTGEFLAAALRTGRAGSNTAVDHIQVLGEAITQIPMPYRRNLLIRCDGAGASHQLLDWLHAQGQVRGRTLHYSVGFTIGEKVRAAITELPAGLWSPALTAEGEVREGGDVAELTGLLDLTSWPAGMRVILRRERPHPGAQLSLFEVHDGWRYQAFATNTTSGTLQFLEARHRAHARVEDRIRHAKDSGLGRFPSREFAINQTWLALTMIAADLVAWLKMLALDGDLAKAEPKALRYRLLHVPARLVHGARRRRLRLPKTWPWVEHLVAAFARIAAIPPPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFR0</accession>
    <name>A0A1Q2CFR0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_09250</name>
        <name evidence="2" type="ORF">SAMN05428934_1272</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000027">
        <property type="protein sequence ID" value="SDZ23797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09250"/>
    <dbReference type="EnsemblBacteria" id="AQP44949">
        <property type="protein sequence ID" value="AQP44949"/>
        <property type="gene ID" value="RPIT_09250"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ23797">
        <property type="protein sequence ID" value="SDZ23797"/>
        <property type="gene ID" value="SAMN05428934_1272"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09250"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ23797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="139" mass="15249" checksum="43AACAFB3C4A6C1E" modified="2017-04-12" version="1">MIPLTGPNSEILFLVRTDFSDDDAWHRVDEVAGREGTNVETVNDPANRHLDAATLASELPTFAQGVLLADHVTMTTSEQLVLVYPTRYDEDEDEVAPFRAPAALLAYVVCPIVLGSRNWSEVGGLVNQDGVFSMDHPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFU4</accession>
    <name>A0A1Q2CFU4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Dihydrofolate reductase</fullName>
            <ecNumber evidence="3 4">1.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_09480</name>
        <name evidence="7" type="ORF">SAMN05428934_102410</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(6S)-5,6,7,8-tetrahydrofolate + NADP(+) = 7,8-dihydrofolate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15009"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the dihydrofolate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.3" evidence="3 4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY60011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09480"/>
    <dbReference type="EnsemblBacteria" id="AQP44986">
        <property type="protein sequence ID" value="AQP44986"/>
        <property type="gene ID" value="RPIT_09480"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY60011">
        <property type="protein sequence ID" value="SDY60011"/>
        <property type="gene ID" value="SAMN05428934_102410"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09480"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00158"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004146">
        <property type="term" value="F:dihydrofolate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006545">
        <property type="term" value="P:glycine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00209">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012259">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069">
        <property type="entry name" value="PTHR48069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000194">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51330">
        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DHFR" evidence="5">
        <location>
            <begin position="2"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY60011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="160" mass="18046" checksum="27899DEA5C9A8AEF" modified="2017-04-12" version="1">MRIVAIAAVADNGVIGSGDDMLWHLPEDFRRFKEVTTGNTLVFGRRTHEQIGRTLPNRRIIVVTRDPDWSDDGVEVAHSIEEALDLAAQTPEKICYIGGGAEIYEAAWPYLTELDITHVHQEPEGAATFPLLSVREWTEISREPRQGFDFTQYRPTPRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFV2</accession>
    <name>A0A1Q2CFV2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maltose alpha-D-glucosyltransferase</fullName>
            <ecNumber evidence="3">5.4.99.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Maltose alpha-D-glucosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_09205</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-maltose = alpha,alpha-trehalose</text>
            <dbReference type="Rhea" id="RHEA:15145"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17306"/>
            <dbReference type="EC" id="5.4.99.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 13 family. TreS subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.16" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09205"/>
    <dbReference type="EnsemblBacteria" id="AQP44940">
        <property type="protein sequence ID" value="AQP44940"/>
        <property type="gene ID" value="RPIT_09205"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09205"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047471">
        <property type="term" value="F:maltose alpha-D-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032091">
        <property type="entry name" value="Malt_amylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012810">
        <property type="entry name" value="TreS/a-amylase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16657">
        <property type="entry name" value="Malt_amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02456">
        <property type="entry name" value="treS_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aamy" evidence="7">
        <location>
            <begin position="39"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="572" mass="64857" checksum="B0782CA0AF5B5B7A" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFZ3</accession>
    <name>A0A1Q2CFZ3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type III restriction enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09345</name>
        <name evidence="4" type="ORF">SAMN05428934_102440</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY60841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09345"/>
    <dbReference type="EnsemblBacteria" id="AQP44965">
        <property type="protein sequence ID" value="AQP44965"/>
        <property type="gene ID" value="RPIT_09345"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY60841">
        <property type="protein sequence ID" value="SDY60841"/>
        <property type="gene ID" value="SAMN05428934_102440"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09345"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ResIII" evidence="2">
        <location>
            <begin position="19"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY60841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="833" mass="92012" checksum="306A9DF006D18950" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG96</accession>
    <name>A0A1Q2CG96_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UDP:flavonoid glycosyltransferase YjiC, YdhE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10340</name>
        <name evidence="2" type="ORF">SAMN05428934_102237</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10340"/>
    <dbReference type="EnsemblBacteria" id="AQP45142">
        <property type="protein sequence ID" value="AQP45142"/>
        <property type="gene ID" value="RPIT_10340"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55234">
        <property type="protein sequence ID" value="SDY55234"/>
        <property type="gene ID" value="SAMN05428934_102237"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10340"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY55234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="420" mass="44173" checksum="5A1732451A4E78BA" modified="2017-04-12" version="1">MNRPRAATFLVVSTSITAHTLNASKIVSGLVGRGHRVLWYAADRFAHTVALCGAEHLPAADDGGFEDTTARGGGLGRVKSLFRDEVVGRAATHRAALAAAVGGTRIDAVISDTLIPAASLSAADLGAPWVTFGDGPLLCWDDGTPPFGTGLPFHPGRAGRRRNRDVQALLDRWLYRPFLDDLNALRLDAGLGTVPTVREATVSPLLHLQGCTPSFEYPRAAGADHVHFVGALGPVPGSAPEVPPTLTRSQRSRPLAMVTQGTLRPDLSELAIPAARALVAEGFDVLVAGAQAGLWNPAPERVTALPRVDYPGALAESDLFVTNGGYTGVTLAVAAGVPIVQAGNSEEKPDIGARVRWSGVGASLRIRNPPVWLLRQTIRRVMGSPARIEASSRLSGESSCYDAAEISARLLGELAERTRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGB1</accession>
    <name>A0A1Q2CGB1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS1634 family transposase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transposase DDE domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10430</name>
        <name evidence="3" type="ORF">SAMN05428934_102219</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY54755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10430"/>
    <dbReference type="EnsemblBacteria" id="AQP45159">
        <property type="protein sequence ID" value="AQP45159"/>
        <property type="gene ID" value="RPIT_10430"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY54755">
        <property type="protein sequence ID" value="SDY54755"/>
        <property type="gene ID" value="SAMN05428934_102219"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10430"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="169"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY54755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="498" mass="55813" checksum="42174691260B8453" modified="2017-04-12" version="1">MSPYVRTVKTASGATAVQVVWSNKRGSKQMDHIGSAHTAEDVEILKSVAQQRMTASQDELDLGDGQPRKRALAIRASRSEHLWEALSAAFRAVGLETTSGGDEVFRQLVLARVIEPTSKLDAIRVLDEIGIKSPSYRTIERRLPLYAADPWRRRLAAGFAAHVGLGPATLVLYDVTTLYFETDQGDGFRESGFSKERRLEPQITIGLLADVRGFPLMVHAFEGNKAETTTMIPVLHQFMAAHRIPEVTVVADAGMLSDGNLKALAAAGLRYIVGQPIPKVFYQLEQWQKTHPGQDPVDQMILTQPWARGSLEAQQSETIYYQYRADRARRSLRGIDEQVRKAADAVAGKTAVKRNRFVRLEGGSKSVNRELEAKTRTLAGWKAYITNLEHPTPEYVIGAYHQLWQIEKSFRMSKSDLRARPIFHHKRDSIEAHLTIVFAALAVVRWLEATTGASIKQLVKTLRRYRTIDIQAGDQIVTAEDPLPDDLTELLDRIHQRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGE3</accession>
    <name>A0A1Q2CGE3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transketolase</fullName>
            <ecNumber evidence="5">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_10275</name>
        <name evidence="12" type="ORF">SAMN05428934_102250</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the transketolase family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10275"/>
    <dbReference type="EnsemblBacteria" id="AQP45130">
        <property type="protein sequence ID" value="AQP45130"/>
        <property type="gene ID" value="RPIT_10275"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55579">
        <property type="protein sequence ID" value="SDY55579"/>
        <property type="gene ID" value="SAMN05428934_102250"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10275"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005478">
        <property type="entry name" value="Transketolase_bac-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="PTHR43522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00232">
        <property type="entry name" value="tktlase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transket_pyr" evidence="10">
        <location>
            <begin position="364"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP45130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY55579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="685" mass="73954" checksum="894FE13F41D6A626" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGG7</accession>
    <name>A0A1Q2CGG7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10650</name>
        <name evidence="3" type="ORF">SAMN05428934_102175</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY53378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10650"/>
    <dbReference type="EnsemblBacteria" id="AQP45197">
        <property type="protein sequence ID" value="AQP45197"/>
        <property type="gene ID" value="RPIT_10650"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY53378">
        <property type="protein sequence ID" value="SDY53378"/>
        <property type="gene ID" value="SAMN05428934_102175"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10650"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY53378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="170" mass="17268" checksum="28DE4099E5FFB022" modified="2017-04-12" version="1">MTTFLIIGAVGVVLVLVTLVVGDILDGVLHLDALDSDLFSISSLAAFIGAFGFGGAIGLGVLHNMVLAVIVGLIIGSLAAWGAVSLTKKLKSDGASFRSDSMIGHPGRVITAIPEGGYGEITISVAGHVRKITAKAEQAIDSGTEVWVSAILSPTAVEVTPTSGPHELIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGI8</accession>
    <name>A0A1Q2CGI8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Assimilatory nitrate reductase (NADH) alpha subunit apoprotein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Nitrite reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_10900</name>
        <name evidence="7" type="ORF">SAMN05428934_102124</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY51776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10900"/>
    <dbReference type="EnsemblBacteria" id="AQP45239">
        <property type="protein sequence ID" value="AQP45239"/>
        <property type="gene ID" value="RPIT_10900"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY51776">
        <property type="protein sequence ID" value="SDY51776"/>
        <property type="gene ID" value="SAMN05428934_102124"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10900"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04879">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2 4" id="KW-0408">Iron</keyword>
    <keyword evidence="3 4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="6"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY51776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="700" mass="73900" checksum="D864FF4617221D7D" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGJ1</accession>
    <name>A0A1Q2CGJ1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_10855</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10855"/>
    <dbReference type="EnsemblBacteria" id="AQP45231">
        <property type="protein sequence ID" value="AQP45231"/>
        <property type="gene ID" value="RPIT_10855"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10855"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="3"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="239"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="380" mass="41494" checksum="308B5D7387C69CE0" modified="2017-04-12" version="1">MRMVPLGEVVQFTNGGTPARSNSEFWEGDIPWITGADITDGGAVSARSFISQAAVARSSTQVLPEGTVLLLTRTSVGKVAILPRPMAINQDITGITPSQAVDTRYLMHFLRASKPQLLRNLRGATIQGVTRQDVGSLEFPLAPLMQQRRIAAILDKADAVRAKRRQVLAHLDTLSQSIFNDMFAGEHQSASLGDLISSGPTNGLYRPEKDYGFGTPILRIDSFHGGEIHAKPLRRVAISSDLIGTYSLRPGDIVVNRVNSMSHLGKSALVRSLDEETVFESNMMRLRVDSGSVLPEYVHGWLQTHESKAQILAKAKQAINQASINQTDVKSLILPLPPLSAQAEYASVVHKIREQSHLSSRGHLEALVRSLQSRAFKGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGP4</accession>
    <name>A0A1Q2CGP4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutamate synthase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">NADPH-dependent glutamate synthase beta chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_11100</name>
        <name evidence="6" type="ORF">SAMN05428934_10284</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY50542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11100"/>
    <dbReference type="EnsemblBacteria" id="AQP45273">
        <property type="protein sequence ID" value="AQP45273"/>
        <property type="gene ID" value="RPIT_11100"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY50542">
        <property type="protein sequence ID" value="SDY50542"/>
        <property type="gene ID" value="SAMN05428934_10284"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11100"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="513"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY50542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="545" mass="60025" checksum="A70AAD4399938387" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGP6</accession>
    <name>A0A1Q2CGP6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Chaperonin GroEL</fullName>
            <ecNumber evidence="9">5.6.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">60 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Chaperonin-60</fullName>
            <shortName evidence="9">Cpn60</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">groEL</name>
        <name evidence="9" type="synonym">groL</name>
        <name evidence="13" type="ORF">RPIT_11200</name>
        <name evidence="14" type="ORF">SAMN05428934_10264</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 11">Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9 11">Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell surface</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Secreted</location>
            <location evidence="8">Capsule</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9 10">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.7" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY49951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11200"/>
    <dbReference type="EnsemblBacteria" id="AQP45292">
        <property type="protein sequence ID" value="AQP45292"/>
        <property type="gene ID" value="RPIT_11200"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY49951">
        <property type="protein sequence ID" value="SDY49951"/>
        <property type="gene ID" value="SAMN05428934_10264"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11200"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042603">
        <property type="term" value="C:capsule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018370">
        <property type="entry name" value="Chaperonin_Cpn60_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="SSF52029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="SSF54849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00296">
        <property type="entry name" value="CHAPERONINS_CPN60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="337"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="29"/>
            <end position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="86"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="476"/>
            <end position="478"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="492"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP45292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY49951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="543" mass="56861" checksum="906BA171BEF5AAD7" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGP7</accession>
    <name>A0A1Q2CGP7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glucosamine-6-phosphate deaminase</fullName>
            <ecNumber evidence="1">3.5.99.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">GlcN6P deaminase</fullName>
            <shortName evidence="1">GNPDA</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Glucosamine-6-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nagB</name>
        <name evidence="3" type="ORF">RPIT_11170</name>
        <name evidence="4" type="ORF">SAMN05428934_10270</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12172"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:75989"/>
            <dbReference type="EC" id="3.5.99.6"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="1">Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-sugar metabolism; N-acetylneuraminate degradation; D-fructose 6-phosphate from N-acetylneuraminate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.5.99.6" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY50121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11170"/>
    <dbReference type="EnsemblBacteria" id="AQP45286">
        <property type="protein sequence ID" value="AQP45286"/>
        <property type="gene ID" value="RPIT_11170"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY50121">
        <property type="protein sequence ID" value="SDY50121"/>
        <property type="gene ID" value="SAMN05428934_10270"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11170"/>
    <dbReference type="UniPathway" id="UPA00629">
        <property type="reaction ID" value="UER00684"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004342">
        <property type="term" value="F:glucosamine-6-phosphate deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019262">
        <property type="term" value="P:N-acetylneuraminate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01399">
        <property type="entry name" value="GlcN6P_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01241">
        <property type="entry name" value="GlcN6P_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004547">
        <property type="entry name" value="Glucosamine6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018321">
        <property type="entry name" value="Glucosamine6P_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11280">
        <property type="entry name" value="PTHR11280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00502">
        <property type="entry name" value="nagB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01161">
        <property type="entry name" value="GLC_GALNAC_ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="1" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine_iso" evidence="2">
        <location>
            <begin position="13"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for enolization step" evidence="1">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="active site" description="For ring-opening step" evidence="1">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for ring-opening step" evidence="1">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="active site" description="For ring-opening step" evidence="1">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="site" description="Part of the allosteric site" evidence="1">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="site" description="Part of the allosteric site" evidence="1">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="site" description="Part of the allosteric site" evidence="1">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="site" description="Part of the allosteric site" evidence="1">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY50121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="262" mass="28290" checksum="669C8FBC1036F5D5" modified="2017-04-12" version="1">MEVVICRDAQEVGELAADRVIAYLEGIHTPVIGLATGSSPLALYAELSRRVQAGTFDFSHGLGFALDEYVGIDPDHPESYRNVIRRTVVEPLKMDPGRVRVPNGFAADLQGAADEYDAAIEEAGGVDVQILGIGSNGHIGFNEPFSSFSSRTRVKTLTPQTREDNARFFNSLDEVPRHCVTQGLGTIMDSRVAVLVATGEHKADAIAAMIEGPVSQRCPASILQFHPRAVIVIDEGAASKLESAEYFRHVAANDHVTGYSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGT3</accession>
    <name>A0A1Q2CGT3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10990"/>
    <dbReference type="EnsemblBacteria" id="AQP45255">
        <property type="protein sequence ID" value="AQP45255"/>
        <property type="gene ID" value="RPIT_10990"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10990"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="483" mass="49452" checksum="AF0FCAADE27A23CF" modified="2017-04-12" version="1">MQRAFLEPSDATYVEVATGQFESTNTNPKTVVFDEPVTTRFVKLTSLSAVGGQAWAHIAELQVRGAAAEAPALLDDPAVEPRVWVSPSSVPVGGSVLVTGGGFAPGEVTVEAGGESVTAVADGFGFVATELTLPAAGQVTVTVSQGDLSASASAEVTAAPATAPVIADLADVSVEVGETVSVQASATGTAPIVFSASGLPAGVAIDPASGVISGEPEAAGSSSVTVTATNEAGSDSTSFTMTVAEAPVVDTTAPAIAAVGPVTGKQGTALSVTFEASDESLPLTYSATGLPAGVSINPSTGVISGTPTGHGVSTATVTVTDAAGNTASTTVRFTIAATAYEFVPTAPYTKPGVHFVNGRQWLTTCEPYSQTQRCRTDIWASVVKKTDTGFVIERGWAFNNLTYLPYMTRAQWASNPLGTPGYFLGTDNAQWRTECDTAATGANACRTYRLTTVYAAHAKPGGGYTFSQSNEWVFNNMVMFRPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGU1</accession>
    <name>A0A1Q2CGU1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lysophospholipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11465"/>
    <dbReference type="EnsemblBacteria" id="AQP45339">
        <property type="protein sequence ID" value="AQP45339"/>
        <property type="gene ID" value="RPIT_11465"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11465"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="78"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="297" mass="31973" checksum="F2302771525C0C6B" modified="2017-04-12" version="1">MRRLTTALASLSGGAALGVLGVAGYTAWSLNGPRRPWPDYAFTPFEVRADSEDVRFATADGVGLAGWWLDQPGSGTVVICAHGHRGTKSDMLGIGSGLWRAGHTVLLFDFRGNGDSDDGPQSLSHHEQADLRAAIDLASSRRPDARIVVVGFSMGASTAILEGATDPRVAAFVLDSPFSTMGEVVAANYRRYRLPSEPIVPLADLINRLRYGYSYAQVRPLDAAPALAPRPVLLIHGTDDRVIPYDHAVQLARAAGPNCELVTFEGVDHCGAYFEDRQGYIDRVARFLDAAVGRARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGU2</accession>
    <name>A0A1Q2CGU2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta-glucosidase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_11385</name>
        <name evidence="6" type="ORF">SAMN05428934_10227</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY48806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11385"/>
    <dbReference type="EnsemblBacteria" id="AQP45324">
        <property type="protein sequence ID" value="AQP45324"/>
        <property type="gene ID" value="RPIT_11385"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY48806">
        <property type="protein sequence ID" value="SDY48806"/>
        <property type="gene ID" value="SAMN05428934_10227"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11385"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="SSF52279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fn3_like" evidence="4">
        <location>
            <begin position="665"/>
            <end position="734"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY48806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="768" mass="81013" checksum="47D8FDD294BC8F17" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGW9</accession>
    <name>A0A1Q2CGW9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate ABC transporter substrate-binding protein, CUT1 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Sugar ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11635</name>
        <name evidence="3" type="ORF">SAMN05428934_106148</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11635"/>
    <dbReference type="EnsemblBacteria" id="AQP45368">
        <property type="protein sequence ID" value="AQP45368"/>
        <property type="gene ID" value="RPIT_11635"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93903">
        <property type="protein sequence ID" value="SDY93903"/>
        <property type="gene ID" value="SAMN05428934_106148"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11635"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544490" evidence="1">
        <location>
            <begin position="23"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY93903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="530" mass="58224" checksum="33159CCEE9CDD8B0" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH04</accession>
    <name>A0A1Q2CH04_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pyridoxine/pyridoxamine 5'-phosphate oxidase</fullName>
            <ecNumber evidence="5">1.4.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">PNP/PMP oxidase</fullName>
            <shortName evidence="5">PNPOx</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Pyridoxal 5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pdxH</name>
        <name evidence="10" type="ORF">RPIT_11790</name>
        <name evidence="11" type="ORF">SAMN05428934_106117</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + O2 + pyridoxamine 5'-phosphate = H2O2 + NH4(+) + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:15817"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58451"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="1.4.3.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O2 + pyridoxine 5'-phosphate = H2O2 + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:15149"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:58589"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="1.4.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 7">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="5 7">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the pyridoxamine 5'-phosphate oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.5" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11790"/>
    <dbReference type="EnsemblBacteria" id="AQP45396">
        <property type="protein sequence ID" value="AQP45396"/>
        <property type="gene ID" value="RPIT_11790"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93245">
        <property type="protein sequence ID" value="SDY93245"/>
        <property type="gene ID" value="SAMN05428934_106117"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11790"/>
    <dbReference type="UniPathway" id="UPA01068">
        <property type="reaction ID" value="UER00304"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004733">
        <property type="term" value="F:pyridoxamine-phosphate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01629">
        <property type="entry name" value="PdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000659">
        <property type="entry name" value="Pyridox_Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019740">
        <property type="entry name" value="Pyridox_Oxase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019576">
        <property type="entry name" value="Pyridoxamine_oxidase_dimer_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851">
        <property type="entry name" value="PTHR10851"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10590">
        <property type="entry name" value="PNP_phzG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000190">
        <property type="entry name" value="Pyd_amn-ph_oxd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00558">
        <property type="entry name" value="pdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01064">
        <property type="entry name" value="PYRIDOX_OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0288">FMN</keyword>
    <keyword evidence="4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="8">
        <location>
            <begin position="33"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="PNP_phzG_C" evidence="9">
        <location>
            <begin position="171"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="7"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5 6">
        <location>
            <begin position="190"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <begin position="60"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <begin position="75"/>
            <end position="76"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <begin position="139"/>
            <end position="140"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000190-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000190-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP45396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY93245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="211" mass="23253" checksum="BE3F873EB258DEC9" modified="2017-04-12" version="1">MTLHDVRRDYSGEALPDDLAGFDPWLFLQGWVDDALEADEAEPTAMVLSTSGADGRPRSRVVLAKEVTPSGIVFFTHLDSPKGREIAAAPGASAVFWWPTLMRQVRVVGAVERLTREDDEAYFASRPRPSQVGAWASHQSAPLASREDLKKAVAEAESRFSGGPVPCPPNWGGYRIVADEIEFWQGQPSRLNDRVRCTVDSDGWSCTRLQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH11</accession>
    <name>A0A1Q2CH11_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DeoR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, DeoR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_11445</name>
        <name evidence="5" type="ORF">SAMN05428934_10215</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY48411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45335">
        <property type="protein sequence ID" value="AQP45335"/>
        <property type="gene ID" value="RPIT_11445"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY48411">
        <property type="protein sequence ID" value="SDY48411"/>
        <property type="gene ID" value="SAMN05428934_10215"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11445"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014036">
        <property type="entry name" value="DeoR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00455">
        <property type="entry name" value="DeoRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00420">
        <property type="entry name" value="HTH_DEOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="3">
        <location>
            <begin position="5"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY48411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="250" mass="26417" checksum="D3A339356C11BF48" modified="2017-04-12" version="1">MTVDRADREGAILARLSGEGALTVSALATDLGVSEVTIRGDLRALEEQGMLVRTRGGARPTTLKSILQREKLNVELKQRIATAAAAMVRDDDNVMIEAGTTTALVARLLAGRAGVQIVTNSALVFNNARINPSVSVILTGGVFRRESESFVGPLAERAVGDFNARLAFLGTDGFSPERGLTTRFVEGGQVAALMRGRAEETWLLADSTKFGQAGFVSFLPLAGITGVITDDGLPPGAVESLEEHTRVLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH24</accession>
    <name>A0A1Q2CH24_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Monosaccharide ABC transporter substrate-binding protein, CUT2 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Sugar ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_11975</name>
        <name evidence="5" type="ORF">SAMN05428934_10680</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11975"/>
    <dbReference type="EnsemblBacteria" id="AQP45428">
        <property type="protein sequence ID" value="AQP45428"/>
        <property type="gene ID" value="RPIT_11975"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92411">
        <property type="protein sequence ID" value="SDY92411"/>
        <property type="gene ID" value="SAMN05428934_10680"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11975"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        </location>
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        <location>
            <begin position="26"/>
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            <end position="51"/>
        </location>
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            <dbReference type="Pfam" id="PF13407"/>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="385" mass="39702" checksum="4BE54A8AC31201A9" modified="2017-04-12" version="1">MKLTRTTAVLAAVLVSTLGLSACGGGRGAETSAPAAPTTQASGSQAATDGASGSEGFAADATIGVALPWLGTQNWKEAETMFDAQLREAGFTPLIQTADQKVPQQQQQIEAMIEQGAKVIVVGPVDGTQLGSVLSKASDAGVAVIGYDRLIENTEAVDAVVQFGSIRTGELQGESLLEGLEATGPGPYNIELFGGGPADPNAPNFFEGAMSVLQPKIDDGTLVVVSGQTDFTQVATPDWDNAKAQARMDSLLSGFYADKEIHGVLSPNDGIARAILTSVKQAGQTTIPVVDGLDAENESIVSIAKGEQYSTVAKPTDALVAKTVELIQALQSGSGLPAADAQEPNGAKDVDIYQLDPVVVTKDNAAEVFADDADRLKLFEDNLAG</sequence>
</entry>
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            </authorList>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="117" mass="13096" checksum="FBD0DC701FC02206" modified="2017-04-12" version="1">MSQTLKPATAAAKLGIYLPAAPEEFRTASLTRDELDELRDNPPAWLIELRRNGPFPRDVVAQKLGVSRSGLARAGVTEALTADEIGELLADPPDWLVRERETHQKVLKEEARLRQER</sequence>
</entry>
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    <reference evidence="2" key="3">
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    </reference>
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        <location>
            <begin position="18"/>
            <end position="1146"/>
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            <dbReference type="EMBL" id="AQP45448.1"/>
        </source>
    </evidence>
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    </evidence>
    <sequence length="1146" mass="123637" checksum="166289445435E230" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH54</accession>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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                <person name="Schumann P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
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            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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            <begin position="38"/>
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        </location>
    </feature>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="AQP45456.1"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="142" mass="15245" checksum="EEF12F9067E61F8F" modified="2017-04-12" version="1">MPSRSNLVLGVVAALVVILAVVAAVIGTSRSPRTADLSTPAGTTEAYITAVVSQDHDVVEDLLDPALGCTSEQLSQMYRPSRASLSIVNAEATGETATVVVEITEHGQGLFDAWAHRESFTLRFDDGRWLVTGEPWPIYMCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH77</accession>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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                <person name="Schumann P."/>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
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                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="SDY92621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11935"/>
    <dbReference type="EnsemblBacteria" id="AQP45420">
        <property type="protein sequence ID" value="AQP45420"/>
        <property type="gene ID" value="RPIT_11935"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92621">
        <property type="protein sequence ID" value="SDY92621"/>
        <property type="gene ID" value="SAMN05428934_10688"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11935"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030077">
        <property type="term" value="C:plasma membrane light-harvesting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045156">
        <property type="term" value="F:electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019684">
        <property type="term" value="P:photosynthesis, light reaction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014747">
        <property type="entry name" value="Bac_photo_RC_H_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRC" evidence="2">
        <location>
            <begin position="4"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY92621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="299" mass="33496" checksum="64AAB902CA6D6FAB" modified="2017-04-12" version="1">MLNESALEAIINATVFDRNGEKVGKVGHLYVDDRTGKPSWVTVNTGFFGLSESFVPVDETLTAHEERIDVPYDKTHIKDAPRIDADGHLDPSQEEELYRYYDRHYTDYDGMDRDTVGTDSDDAHRLAEPSASAGTLLADSGQPSDTTLTEEVETLKEERAEHDEILSEHIDPDREREQYRGEVYPDDVRAEDFPPSDAYADDVRREVLSDDGGDSTAGHLPGPGDHTRSDPYGDEPRRDGVLTDDTRTEDFAPDADLPRGGVDADDVDYSGRDTVTPRARLRRYERNPRLGEPGLEDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH91</accession>
    <name>A0A1Q2CH91_9ACTN</name>
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        <submittedName>
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    </protein>
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        <name evidence="3" type="ORF">RPIT_12235</name>
        <name evidence="4" type="ORF">SAMN05428934_10629</name>
    </gene>
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY91310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12235"/>
    <dbReference type="EnsemblBacteria" id="AQP45477">
        <property type="protein sequence ID" value="AQP45477"/>
        <property type="gene ID" value="RPIT_12235"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY91310">
        <property type="protein sequence ID" value="SDY91310"/>
        <property type="gene ID" value="SAMN05428934_10629"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12235"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027381">
        <property type="entry name" value="LytR/CpsA/Psr_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13399">
        <property type="entry name" value="LytR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LytR_C" evidence="2">
        <location>
            <begin position="56"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY91310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="189" mass="20396" checksum="76D0B70A2ACC5710" modified="2017-04-12" version="1">MRIFRLIATPVILLGLLALLIWGASWGWKALTEPLPSPSPTPCVVEEAELLNVTHVSVRIFNGGFTSGLANREARRLTEVGFKVIRVDNTDERIRGTVIRANENQTGQIRLVKSYFLEPTVEYDDRIDGTVDIYLGTDFLGANDGSDPANPPLFQVSAPDGQICVVPEPSPSPSPSLSGSPSPTAAETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHE0</accession>
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        <name evidence="1" type="ORF">RPIT_12265</name>
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    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
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        <lineage>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12265"/>
    <dbReference type="EnsemblBacteria" id="AQP45480">
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        <property type="gene ID" value="RPIT_12265"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12265"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023869">
        <property type="entry name" value="tRNA_Adeno_NH3ase_assoc_put"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03941">
        <property type="entry name" value="tRNA_deam_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="207" mass="22976" checksum="E5A198B1AB19C7EA" modified="2017-04-12" version="1">MDCVRRWVPEPRKGDVVDVFDEDAEPFDLNDEGDDVDDEDLDFDDLEDATEDDVDLVVALYREDGKAVAVPLDYDLANDLDELVSQLSRLPGDSGADGWVSVAGEFFVICRVRGRTVEVLLSDITAAQDWPIARDVVDYLGEEMPDEDDDSVPLGDLEMYAASGLRAFELEAIATDYDEDSDVLLGRIAKKLKVADVFERAAEAFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHI5</accession>
    <name>A0A1Q2CHI5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mannitol-1-phosphate 5-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_12860</name>
        <name evidence="4" type="ORF">SAMN05428934_104115</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY78158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12860"/>
    <dbReference type="EnsemblBacteria" id="AQP45586">
        <property type="protein sequence ID" value="AQP45586"/>
        <property type="gene ID" value="RPIT_12860"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY78158">
        <property type="protein sequence ID" value="SDY78158"/>
        <property type="gene ID" value="SAMN05428934_104115"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12860"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013118">
        <property type="entry name" value="Mannitol_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013131">
        <property type="entry name" value="Mannitol_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Mannitol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08125">
        <property type="entry name" value="Mannitol_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mannitol_dh" evidence="1">
        <location>
            <begin position="3"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Mannitol_dh_C" evidence="2">
        <location>
            <begin position="151"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY78158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="392" mass="42169" checksum="EF3C2484B7BE9508" modified="2017-04-12" version="1">MNRIVVFGAGSVGRGFIGQIFAEAGWRVTFVDLESRLVQALNTGSYRHVTLSDEGVEETTITGVDAIDGRDTAAVASAVASADFLATSVGAANLRHIAPTMAEGLRLRISERRGPVDILLAENLHGVGGEMRSLLADALGDDADAVLAQVGTLETSIGRMIPVPNEQRREHEPGWVAVEPYRELPLDVAASRAPLPDVPELVGRTDVPFAFYSDRKLYLHNLGHCLTAYLGELLGEDEIAEAIRRPQIHRIVQTVMATAAAALSLEYGEPLASVQANADDLLRRFHNRALHDTVERVGRDPQRKLAEGDRFLGALALAARHGLARPITVAVAVGADKLLGSVPADQRDSELDRIRSVVAHHGGEDQLAVFDEALSALRTSPDLERLALLLDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHJ0</accession>
    <name>A0A1Q2CHJ0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cupin</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Mannose-6-phosphate isomerase, cupin superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_12810</name>
        <name evidence="4" type="ORF">SAMN05428934_104125</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY78425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12810"/>
    <dbReference type="EnsemblBacteria" id="AQP45577">
        <property type="protein sequence ID" value="AQP45577"/>
        <property type="gene ID" value="RPIT_12810"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY78425">
        <property type="protein sequence ID" value="SDY78425"/>
        <property type="gene ID" value="SAMN05428934_104125"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12810"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="2">
        <location>
            <begin position="39"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY78425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="150" mass="16726" checksum="037AA1D4CD5F6C82" modified="2017-04-12" version="1">MDIRDNGPNPNAFDLETATVENRFYRQVAWTGKYLQVTLMSIPVGESIGLEVHPDTDQFVRLDAGKGKAVMGPEKDDLNWSQDVSDGWSVQVPAGMWHDITNTGDEPMRLYVIYAPSHHAPGKVHPTRAESEADEESGADEPPEWTHQPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHK4</accession>
    <name>A0A1Q2CHK4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycosyltransferase involved in cell wall bisynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_12940</name>
        <name evidence="6" type="ORF">SAMN05428934_10499</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12940"/>
    <dbReference type="EnsemblBacteria" id="AQP45599">
        <property type="protein sequence ID" value="AQP45599"/>
        <property type="gene ID" value="RPIT_12940"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY77732">
        <property type="protein sequence ID" value="SDY77732"/>
        <property type="gene ID" value="SAMN05428934_10499"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12940"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="4">
        <location>
            <begin position="29"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="3">
        <location>
            <begin position="238"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY77732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="429" mass="46741" checksum="8D0661C98977BD65" modified="2017-04-12" version="1">MTHAADRRPLRVAQFVDNYGPGSNGLMFAVQQLEGNLLDAGHEVIVVAPAAKGPNPHHGRAGRTELRLPSVRVPKMPTRVANGRHFDRTIDKLGALKPDVIHVHGFGTVGLLGIWAARRLGIPTILTWHTDFDAYADHYSTVLPLLTGVLRAFAVWSRGEVVDRNDLKLAEIRYEDRGRSTASLLGVCEKMLRSADLVTTPSPKTATRCREIVPEASILVVPNGVDPLPPGPPPFTREPGPLVLYAGRIAPEKGIPLLAEAFHLVHAQRPDARLMIVGDWQRYPRIRKVLAEGAAQGKFILTGEKKRDELGAYYGMADLFAFPSETDTQALVLHEAALAGLPIVSVDHELRLVIEPGVNGEITRPTAASLAAGIMRVIARLEDDEWRTRASARSIELASQWTIRSQADEILRLYAEVAAGPAGERAVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHN5</accession>
    <name>A0A1Q2CHN5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Activator of Hsp90 ATPase homolog 1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13060</name>
        <name evidence="3" type="ORF">SAMN05428934_10475</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45622">
        <property type="protein sequence ID" value="AQP45622"/>
        <property type="gene ID" value="RPIT_13060"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY77076">
        <property type="protein sequence ID" value="SDY77076"/>
        <property type="gene ID" value="SAMN05428934_10475"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13060"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="Activator_of_Hsp90_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY77076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="133" mass="14833" checksum="5D3F019E2A669E07" modified="2017-04-12" version="1">MDTVAEELTDSKSVKVTHVVARPLDNVWGALMKPQGAAALLGEGGELGNKGEDWRANDGTYGVTRSFHPKEQIRFSWHASEGAPRTLVDLHLRPAGDQTELEIAHEHLPEDADTEELRRRWREVLTRIEEASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHQ7</accession>
    <name>A0A1Q2CHQ7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fumarate hydratase class II</fullName>
            <shortName evidence="2">Fumarase C</shortName>
            <ecNumber evidence="2">4.2.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Aerobic fumarase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Iron-independent fumarase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fumC</name>
        <name evidence="5" type="ORF">RPIT_12945</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(S)-malate = fumarate + H2O</text>
            <dbReference type="Rhea" id="RHEA:12460"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="4.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; (S)-malate from fumarate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12945"/>
    <dbReference type="EnsemblBacteria" id="AQP45600">
        <property type="protein sequence ID" value="AQP45600"/>
        <property type="gene ID" value="RPIT_12945"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12945"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045239">
        <property type="term" value="C:tricarboxylic acid cycle enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006106">
        <property type="term" value="P:fumarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01362">
        <property type="entry name" value="Fumarase_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00743">
        <property type="entry name" value="FumaraseC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005677">
        <property type="entry name" value="Fum_hydII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444">
        <property type="entry name" value="PTHR11444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00979">
        <property type="entry name" value="fumC_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lyase_1" evidence="3">
        <location>
            <begin position="11"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="FumaraseC_C" evidence="4">
        <location>
            <begin position="409"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="99"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding (B site)" evidence="2">
        <location>
            <begin position="130"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="140"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="325"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="319"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="2">
        <location>
            <position position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="462" mass="49660" checksum="3B7639FA225724A2" modified="2017-04-12" version="1">MDMRIETDSFGEIEVAADRYWGAQTERSLHNFDIGRDTFVWGRAMVRALGILKKAAAQANGELGELPADVADLIVQAADEVIAGNLDDHFPLVVFQTGSGTQSNMNSNEVISNRAIELAGGEMGSKKPVHPNDHVNRGQSSNDTFPTAMHIAIVNELNERLYPAIARLREVLAAKAEEYDDVVMVGRTHLQDATPVRLGQVFGGWVAQLDFALDGIRFADERARDLAIGGTAVGTGLNAHPDFGKLAAEKISAETGLEFRQADNLFAALSAHDSLVEVSGSLRVLADALMKLANDVRWYASGPRNGIGELTIPENEPGSSIMPGKVNPTQSEALTMVVARVLGNDAAVGFAGSQGNFQLNVFKPVMAHAVLESIRLLADGARSFTEHCAVGIEPNTQRIEANLQSNLMLVTALNRHIGYDLAAKIAKQAHKEGTSLKESALANGVSSEDFDRWVVPSEMTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHV2</accession>
    <name>A0A1Q2CHV2_9ACTN</name>
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        <recommendedName>
            <fullName evidence="1">ThuA domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="2" type="ORF">RPIT_13410</name>
        <name evidence="3" type="ORF">SAMN05428934_1046</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP45684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY75136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13410"/>
    <dbReference type="EnsemblBacteria" id="AQP45684">
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        <property type="gene ID" value="RPIT_13410"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY75136">
        <property type="protein sequence ID" value="SDY75136"/>
        <property type="gene ID" value="SAMN05428934_1046"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13410"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029010">
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    <dbReference type="Pfam" id="PF06283">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ThuA" evidence="1">
        <location>
            <begin position="17"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY75136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="217" mass="23519" checksum="D2ED656CC00A548A" modified="2017-04-12" version="1">MARILIASGVGPYADPWHPFERTSPLIADVLRDAGHEVHVRETVPGALLDVASFDLFVANAGGGIADGEAPSDSLMDDLEALKRYLIDGGRVLSIHTSNGAFGQLPEWRSAVGGHWGADSWHPDISDATFAPAPGAGEHPVWEGLRTIEVFDEKYSGLVIDDGVTPLVQHELEGRPEVMGWAVGHRVIFDGLGHDERSYESESRRQLLVNEVAWLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHV6</accession>
    <name>A0A1Q2CHV6_9ACTN</name>
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        <submittedName>
            <fullName evidence="6">Monosaccharide ABC transporter ATP-binding protein, CUT2 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Sugar ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_13285</name>
        <name evidence="6" type="ORF">SAMN05428934_10430</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY75823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13285"/>
    <dbReference type="EnsemblBacteria" id="AQP45663">
        <property type="protein sequence ID" value="AQP45663"/>
        <property type="gene ID" value="RPIT_13285"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY75823">
        <property type="protein sequence ID" value="SDY75823"/>
        <property type="gene ID" value="SAMN05428934_10430"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13285"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="9"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="256"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY75823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="500" mass="53843" checksum="1B2CCDB964566B6B" modified="2017-04-12" version="1">MTRTPPPRLSTRGLSRDYGPVRVVDDVSLQFHAGTIHALLGENGAGKSTVVKMLSGVIQPTEGEVLLDGSPLELSNVREGQASGIIALPQELTLVPTLSVAENIFLGMKRPGRRVLHQPRVLSRDARAQLDRLGQKLPMGVPVRELSAVQQTMVALARALVRDARVLILDEPTASLTDSETEQLFAVLRSLREQGTTIIYVSHRLEEVFALADEATVMRNGRHVWTRPIAELDQDQVISAMIGRAQGQLFPDRATGGGDPVLHADGVAGYTVDDVSLTLRRGRVLGIAGLAGSGRSELLRILSGAERAQRGRVLLGDDDLTGRSIAARMSAGVVLVPEERRSQGLVMTHSIASNIALGNYPSLSTAGVASPSREAATASRLVDDLQIRARSIRQRVNELSGGNQQKVVLARYLERRPSVLLLDEPTRGIDVGTKAEIYHLIRRLADEGVAVAVVSSEIPELLGVADEIAVLHDGRLTGVVDAATATEESITHLCYRKSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI05</accession>
    <name>A0A1Q2CI05_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyltransferase EpsE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13855</name>
        <name evidence="4" type="ORF">SAMN05428934_11129</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13855"/>
    <dbReference type="EnsemblBacteria" id="AQP45756">
        <property type="protein sequence ID" value="AQP45756"/>
        <property type="gene ID" value="RPIT_13855"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12122">
        <property type="protein sequence ID" value="SDZ12122"/>
        <property type="gene ID" value="SAMN05428934_11129"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13855"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544522" evidence="1">
        <location>
            <begin position="22"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="7"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ12122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="284" mass="31955" checksum="7D8CD11482AB7CEB" modified="2017-04-12" version="1">MTTPRVSIIMAVLNAQTTLEAALASIAAQTFTDWEFVICDDGSSDETAEILASFRSTLGAERVTVLTNPVNRKLAYSLNRCLDAARGEFIARMDGDDLSEPDRLEKQLAYLDDHADVDLVGTAMRRFNGGGLGEVVQPAAEAPDRWVLARASGAPFFHATVLARRAVFDAVGNYTVSWRTERCEDLDLWYKFFAAGLRGRNLSEPLYRVREDAAAIRRRRPWGRLGSFATSFKGAWMLGYPPSAYIRELANLMKIFVPYRVFDLHRAWTQSRASRHDRPNRESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI07</accession>
    <name>A0A1Q2CI07_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_13865</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45758">
        <property type="protein sequence ID" value="AQP45758"/>
        <property type="gene ID" value="RPIT_13865"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13865"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13477">
        <property type="entry name" value="Glyco_trans_4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="4">
        <location>
            <begin position="9"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="3">
        <location>
            <begin position="184"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="364" mass="40175" checksum="E411C326D915192D" modified="2017-04-12" version="1">MLVFANDYTSVFHFRRELLRRLVSDGHAVELVLPVDDRNQAFAEIGCSVTQLPLSRFGTNPIEELGTLVRFMKIVRSARPDVLVTFTAKPNIYGGIASQICRVPLVSAVTGLGATFQQPGFLRTGMTLLYRLALRGASRVMFENSSNRQLFLDRHVVAEGNSTVVSGAGVNLAENPLVPYPEKQDVTRFIAVARVRRDKGYDQLFEAIKQVCAHRDDVEFHIVGWYEDESYRQRLLEVAADYPVIVHGGVSQEQVRGLLAQADCLIHPSHHEGMANVILEASAAGRPCLVSDIPGCREAVDSEVSGFLFPAKDAPALAECVERFTGLPTEQRRQMGLAARQKMELEFGRDAVVDSYVAAIMEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI10</accession>
    <name>A0A1Q2CI10_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Site-specific recombinase XerD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_13500</name>
        <name evidence="5" type="ORF">SAMN05428934_11199</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ13354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13500"/>
    <dbReference type="EnsemblBacteria" id="AQP45700">
        <property type="protein sequence ID" value="AQP45700"/>
        <property type="gene ID" value="RPIT_13500"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ13354">
        <property type="protein sequence ID" value="SDZ13354"/>
        <property type="gene ID" value="SAMN05428934_11199"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13500"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="178"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ13354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="386" mass="43247" checksum="EABC5101A363CE8F" modified="2017-04-12" version="1">MARAPRRLPLGILLLPSGNYRVRYLGPDGKRYSKTFTHLQDARYWQASEQRLIDQDGWTPPEVRQRRQDSAALTVAEWAEQRILAWSTRSRSPIVGSTVEDYRRCLRLRIDGWLGDTPLTLVTAAIVRKWHEALPDTPTMNGKAYDLLKHLMNDAVNDELIAANPCRIVGAGKPRAKGAAEALSASDIGPYLEAVEEYYRPALAVGGLRSGEVRGLRRRDLDVEQGFIRVAGAIRREQVAEGEYKRDYTDTKTPAGKRVIYLPAAVLDYLRPWVQNHTFAPDELLFPARRTGKIMNETVLAAAHRRAARQIGRPTLTLHNLRATAATLTKQAGMTDREVQRRFGHTTAAMANLYQVPELEPDKSGAAMIDSLLQSRGHQARLPSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI22</accession>
    <name>A0A1Q2CI22_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07530</name>
        <name evidence="2" type="ORF">RPIT_13995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44676">
        <property type="protein sequence ID" value="AQP44676"/>
        <property type="gene ID" value="RPIT_07530"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45776">
        <property type="protein sequence ID" value="AQP45776"/>
        <property type="gene ID" value="RPIT_13995"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07530"/>
    <dbReference type="KEGG" id="tfl:RPIT_13995"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="105" mass="11354" checksum="847F7BE4A85D50D4" modified="2017-04-12" version="1">MGRPPVIPVEKKTRIVLSILAGEMTIAEAARREKVSEQSIGRWKADFLEAGKAGLAAGRSGPSTREQQLEAEVTELTQALGEAAVEIRVWKKSAEGRLGPSRTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI33</accession>
    <name>A0A1Q2CI33_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Membrane protein insertase YidC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Foldase YidC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Membrane integrase YidC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Membrane protein YidC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">RPIT_13585</name>
        <name evidence="17" type="ORF">SAMN05428934_11182</name>
    </gene>
    <organism evidence="16 18">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 18" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1T</strain>
        </source>
    </reference>
    <reference evidence="17 19" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">RP1</strain>
        </source>
    </reference>
    <reference evidence="16" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ13081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13585"/>
    <dbReference type="EnsemblBacteria" id="AQP45715">
        <property type="protein sequence ID" value="AQP45715"/>
        <property type="gene ID" value="RPIT_13585"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ13081">
        <property type="protein sequence ID" value="SDZ13081"/>
        <property type="gene ID" value="SAMN05428934_11182"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13585"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="Membr_insert_YidC/Oxa1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="PTHR12428"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03592">
        <property type="entry name" value="yidC_oxa1_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="227"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="299"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="335"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="AQP45715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="SDZ13081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="374" mass="41910" checksum="2002BA524B729172" modified="2017-04-12" version="1">MVDLLVSLNIFDSFYGLLSAMMQPLYWAVSGLVVFFHSVFTPLLGADNGWNWALAIVSLTVVIRTLLIPLFVKQINSARNMQLLQPKLAELQKKYGADRERLGQETMKLYQSEGVNPMASCLPLLLQMPIFLALFRVLEGASSGNVRGHFFKENPQLVESLQRAEIFGAGLADRLLPFTPFGSTQVVAIVLVILMVGIFWLTQVQLMRKNMPPESQVGQAAQMQKMMLYFFPFIYAMSAIVIPIGVLVYWLTSNVWTYAQQAILIRNNPAPNTPAYIDWEERMLAKGKDPQQIVLARAEKRRRTKKAPAAPRTVQGATATASPAEGDEQATVTDDAPKVTRQQVTRQTVRTTDDGRRIVQRGPQNKSRASRKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI41</accession>
    <name>A0A1Q2CI41_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cell division protein DedD</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">dCMP deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_13650</name>
        <name evidence="9" type="ORF">SAMN05428934_11169</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13650"/>
    <dbReference type="EnsemblBacteria" id="AQP45725">
        <property type="protein sequence ID" value="AQP45725"/>
        <property type="gene ID" value="RPIT_13650"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12858">
        <property type="protein sequence ID" value="SDZ12858"/>
        <property type="gene ID" value="SAMN05428934_11169"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13650"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004132">
        <property type="term" value="F:dCMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006220">
        <property type="term" value="P:pyrimidine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01286">
        <property type="entry name" value="deoxycytidylate_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016473">
        <property type="entry name" value="dCMP_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015517">
        <property type="entry name" value="dCMP_deaminase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035105">
        <property type="entry name" value="Deoxycytidylate_deaminase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11086">
        <property type="entry name" value="PTHR11086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006019">
        <property type="entry name" value="dCMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="7">
        <location>
            <begin position="12"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR006019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ12858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="152" mass="16057" checksum="15FB638A7A3C80B3" modified="2017-04-12" version="1">MDSSPVTHTVPGWDEYFLQIADAVSARAKCTRRRVGAVLVVERRIIATGYNGAASGEPDCLEGACPRGALDYGTVPGLGDYDRPGTPGFCIAIHAEVNALLFATRDTAGATAYITDPPCPGCRKALAAAGIARVVWPDGVYDGRGEIMDWSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI55</accession>
    <name>A0A1Q2CI55_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Chromate transport protein ChrA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_14160</name>
        <name evidence="9" type="ORF">SAMN05428934_11213</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ14403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14160"/>
    <dbReference type="EnsemblBacteria" id="AQP45806">
        <property type="protein sequence ID" value="AQP45806"/>
        <property type="gene ID" value="RPIT_14160"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ14403">
        <property type="protein sequence ID" value="SDZ14403"/>
        <property type="gene ID" value="SAMN05428934_11213"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14160"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015109">
        <property type="term" value="F:chromate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003370">
        <property type="entry name" value="Chromate_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02417">
        <property type="entry name" value="Chromate_transp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="361"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="395"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="421"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ14403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="438" mass="43903" checksum="AE4A10C8DA5F1448" modified="2017-04-12" version="1">MEELKGGPRQVLSAMLTAGVIGFGGGSALIPVMERLTVHKGLLAAATYTRHVVVANITPGALPVKLAAAAGLNRGGARLSTASALVVALPGALATLLLMVGISALGEGGLNLLNFASVGITAFIIALLAGYVIKVHSHAGSAWPKFALITAVTAAATGANVIAAVGAELLGLPEPSGELPQLSAVQVILAALVAISVASLVAHRGEERSQSRLQLRSMTSIWRATAAFAVLTALGLGLFVVAAGTSGLAFGSLLALSTITAFGGGEAYIAVADGFFVQPGLIDAGVFYTQLVPIANALPGPILVKVGVGSSYLFGVAHGAWQGWALGGAGLLITVGACCALAVPVLGLYKQLKDHPVIVGIGRYILPVICGLLVSVAATMLEVSAGVMEDVVDPVGPALWVLVAAAAILTVLHVRKLAPDLVLLAVAGVLSLVALLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI71</accession>
    <name>A0A1Q2CI71_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD(P)H-dependent FMN reductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">NADPH-dependent FMN reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14190</name>
        <name evidence="3" type="ORF">SAMN05428934_11220</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ14565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14190"/>
    <dbReference type="EnsemblBacteria" id="AQP45811">
        <property type="protein sequence ID" value="AQP45811"/>
        <property type="gene ID" value="RPIT_14190"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ14565">
        <property type="protein sequence ID" value="SDZ14565"/>
        <property type="gene ID" value="SAMN05428934_11220"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14190"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ14565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="178" mass="19613" checksum="AF8099ED0D86D54E" modified="2017-04-12" version="1">MKVGIIVGSIRDGRVGRGIADWVYEIASKRDDAEYELIDLKEFNVPLLTSGTHPMAAKRKYDSEEVQAWSNAIDPCDAYVFVTPEYNHGVPGALKNAVDCLGEEWIGKTIAFVGYGSVGGVRAIEHWRSIVANFSMVDIRAEVNISLFADFKEGTFTPIDRRPDEVNALFDALVKAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CII4</accession>
    <name>A0A1Q2CII4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01185</name>
        <name evidence="3" type="ORF">SAMN05428934_105186</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY88353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45948">
        <property type="protein sequence ID" value="AQP45948"/>
        <property type="gene ID" value="RPIT_01185"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY88353">
        <property type="protein sequence ID" value="SDY88353"/>
        <property type="gene ID" value="SAMN05428934_105186"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01185"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY88353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="64" mass="7198" checksum="50242D8C1BB6BAEF" modified="2017-04-12" version="1">MSERVHEQQLTAPAGSTVADLSKAPLPTPATLRKRMSLPLQVVRFFVFNARIMRMVLKGHSQDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIK4</accession>
    <name>A0A1Q2CIK4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_14570</name>
        <name evidence="2" type="ORF">SAMN05428934_109100</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14570"/>
    <dbReference type="EnsemblBacteria" id="AQP45880">
        <property type="protein sequence ID" value="AQP45880"/>
        <property type="gene ID" value="RPIT_14570"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06508">
        <property type="protein sequence ID" value="SDZ06508"/>
        <property type="gene ID" value="SAMN05428934_109100"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14570"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ06508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="225" mass="23368" checksum="149FCDF2C6554BFF" modified="2017-04-12" version="1">MRKAIVTGSSRGLGEALARQLREAGWDVLGLSRADGVDLSSVDALSTWLGRGTLEQFLAEATDVVLVNNAGTVGPVAEVGAQSPDAISEAVTLNVTAPLVLTDAVVRHRPAGVPVRVVHISSGAGRHPYPTWSVYCATKAAVDMHALALAEEGIDGVRAASVAPGIVDTDMQASIRETEGFPLRDTFIGYKESGALSSPDDAAAKILRLIESPDFGTSPVTDVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIN8</accession>
    <name>A0A1Q2CIN8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_01940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01940"/>
    <dbReference type="EnsemblBacteria" id="AQP45972">
        <property type="protein sequence ID" value="AQP45972"/>
        <property type="gene ID" value="RPIT_01940"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01940"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="120" mass="13107" checksum="352104B223C6A5F6" modified="2017-04-12" version="1">MMADCPCGGGSWDECCGPLLAGTRQAGTAEALMRSRYSAFVFGDSDHLWRTWHPRTRPASVDAAGVEWLRLEVLDVVGGGEDDAEGVVEFDAHHAGGVLHERSRFARRAGRWFYLDAATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIR8</accession>
    <name>A0A1Q2CIR8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">4-hydroxy-tetrahydrodipicolinate reductase</fullName>
            <shortName evidence="9">HTPA reductase</shortName>
            <ecNumber evidence="9">1.17.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dapB</name>
        <name evidence="12" type="ORF">RPIT_04645</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + NAD(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:35323"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="EC" id="1.17.1.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + NADP(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:35331"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="EC" id="1.17.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the DapB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.8" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04645"/>
    <dbReference type="EnsemblBacteria" id="AQP46019">
        <property type="protein sequence ID" value="AQP46019"/>
        <property type="gene ID" value="RPIT_04645"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04645"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00018"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008839">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate reductase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016726">
        <property type="term" value="F:oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00102">
        <property type="entry name" value="DapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022663">
        <property type="entry name" value="DapB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000846">
        <property type="entry name" value="DapB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022664">
        <property type="entry name" value="DapB_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023940">
        <property type="entry name" value="DHDPR_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20836">
        <property type="entry name" value="PTHR20836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05173">
        <property type="entry name" value="DapB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01113">
        <property type="entry name" value="DapB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000161">
        <property type="entry name" value="DHPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00036">
        <property type="entry name" value="dapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01298">
        <property type="entry name" value="DAPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0520">NAD</keyword>
    <keyword evidence="4 9" id="KW-0521">NADP</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DapB_N" evidence="10">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="DapB_C" evidence="11">
        <location>
            <begin position="106"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="(S)-2,3,4,5-tetrahydrodipicolinate binding" evidence="9">
        <location>
            <begin position="140"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="7"/>
            <end position="12"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="73"/>
            <end position="75"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="100"/>
            <end position="103"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>(S)-2,3,4,5-tetrahydrodipicolinate</name>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP46019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="243" mass="25952" checksum="EE903F9ED4AF96CA" modified="2017-04-12" version="1">MQVGIFGVSGKMGSEVVRAVTRADGMTTVGGVDINEDRDKIGRAQVVVDFTHPDSVMDNIEWCLQLGIHMVIGTTGFTEERLERVRELCEAHPEVGVLIASNFSIGAVLMMKFAALAAPFYESAEIVELHHPNKADAPSGTSATTARRIAAARAEAGLGEVPDATVHDDGARGAVVDGIHVHGVRLRGLVAHQEVLFGAEGETLTIRHDSFDRVSFMPGVVAAIRHVVEQPGLTLEMEQVLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIT0</accession>
    <name>A0A1Q2CIT0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF45 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04785</name>
        <name evidence="3" type="ORF">SAMN05428934_101566</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY38526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP46021">
        <property type="protein sequence ID" value="AQP46021"/>
        <property type="gene ID" value="RPIT_04785"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY38526">
        <property type="protein sequence ID" value="SDY38526"/>
        <property type="gene ID" value="SAMN05428934_101566"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04785"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002725">
        <property type="entry name" value="YgjP-like_metallopeptidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01863">
        <property type="entry name" value="DUF45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF45" evidence="1">
        <location>
            <begin position="29"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY38526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="234" mass="26940" checksum="88EF3B967B0F8482" modified="2017-04-12" version="1">MRRMNKRTLWTDSLTVDGIEAEVTYKDIKNIRLRVLPPDGRVRVSAPYRTPAENVERFVISQRDWIVQARAKARLMAPAREPLTDGGRALLWGEWHEVRLEEGRRVSARVDGRTIRLSAADEGERRQALENLYRAEIQSAVPALHDRWAAITGRAASTFRYRRMTSRWGSCQPATGAISLNIALAERRPELLEYVLVHELTHLWERGHGPAFYARMDAALPDWRRRRGQLKGPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIW7</accession>
    <name>A0A1Q2CIW7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA polymerase sigma factor, sigma-70 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_06475</name>
        <name evidence="6" type="ORF">SAMN05428934_103240</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06475"/>
    <dbReference type="EnsemblBacteria" id="AQP46057">
        <property type="protein sequence ID" value="AQP46057"/>
        <property type="gene ID" value="RPIT_06475"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71330">
        <property type="protein sequence ID" value="SDY71330"/>
        <property type="gene ID" value="SAMN05428934_103240"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06475"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="4">
        <location>
            <begin position="32"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP46057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY71330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="189" mass="19962" checksum="1B21DFB41B19A1A4" modified="2017-04-12" version="1">MSAPATSSLSGQAAAAFAAYRSGETGRMSELVSLLTPALWAVARSAGLDSAKAEDVVQSAWEALVRKADTIDDPQAVFAWLLTTTRRAAWRAAGARREEPLVEDSPAPTPTPETIVLDEDRGLRLWRHVKALSPRCQALIRVIAFAPTPDYAAISAALGMPVGSIGPTRGRCLAALRAALADDPAWSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIX1</accession>
    <name>A0A1Q2CIX1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_06800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06800"/>
    <dbReference type="EnsemblBacteria" id="AQP46061">
        <property type="protein sequence ID" value="AQP46061"/>
        <property type="gene ID" value="RPIT_06800"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06800"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014293">
        <property type="entry name" value="RNA_pol_sigma70_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000838">
        <property type="entry name" value="RNA_pol_sigma70_ECF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02947">
        <property type="entry name" value="SigH_actino"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01063">
        <property type="entry name" value="SIGMA70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="26"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="133"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP46061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="199" mass="22094" checksum="941B5099173FF1C5" modified="2017-04-12" version="1">MEQELSTSLADDTLDADAAFEEEALSHLDRLYAAALRMTRNPADAEDVVQDTYAKAFSSRHTFTPGTNLRAWLYRILTNTYINSYRKAQRSPQTSGDEDVSDWQLARAASHDSAGLRSAEMEALDQTPDAVVADALAQLPENFRMAVLLSDVEGFSYKEIAEIMGTPIGTVMSRLNRGRAQLRDLLADYARDKGIGRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIZ0</accession>
    <name>A0A1Q2CIZ0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pyridoxal kinase</fullName>
            <ecNumber evidence="1">2.7.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05965</name>
        <name evidence="4" type="ORF">SAMN05428934_103139</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.35" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05965"/>
    <dbReference type="EnsemblBacteria" id="AQP46043">
        <property type="protein sequence ID" value="AQP46043"/>
        <property type="gene ID" value="RPIT_05965"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68702">
        <property type="protein sequence ID" value="SDY68702"/>
        <property type="gene ID" value="SAMN05428934_103139"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05965"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008478">
        <property type="term" value="F:pyridoxal kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009443">
        <property type="term" value="P:pyridoxal 5'-phosphate salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01173">
        <property type="entry name" value="pyridoxal_pyridoxamine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013749">
        <property type="entry name" value="PM/HMP-P_kinase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004625">
        <property type="entry name" value="PyrdxlKinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10534">
        <property type="entry name" value="PTHR10534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08543">
        <property type="entry name" value="Phos_pyr_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00687">
        <property type="entry name" value="pyridox_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phos_pyr_kin" evidence="2">
        <location>
            <begin position="73"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY68702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="280" mass="30420" checksum="6160E293696E6291" modified="2017-04-12" version="1">MSIQSAVAYGHAGNSSAVFPLQRLGVDVWPVYTVNFSNHTGYGAWRGPLIPAADVWEVVQGVNDRGVLNQADALLCGYLGTPEVGQVILDSAALIREQNPDAVFCADPVMGDADRGFYARPGIPEFWRDHVVARADIMTPNLFELEFLTGHPTSTLSEVLGAVDELRQRGPSVVVVTSVVGEDLGDDAMRMIGVSDDGAWIVETPVLDRTFTGSGDLTTAMFLAHWLRSRDVSEALGATASIVYSILEHTTRVGHRELRLVAAQDDIVAPRHRFEARPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ53</accession>
    <name>A0A1Q2CJ53_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_07285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP46075">
        <property type="protein sequence ID" value="AQP46075"/>
        <property type="gene ID" value="RPIT_07285"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07285"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="134" mass="13999" checksum="46D545CE7041BCB9" modified="2017-04-12" version="1">MTGGRRGFWGALWAGTRATLGALMGLAPHVMHHIGFLAGAALLTGFLGNTLLYVVGLALSIPLLRRLHRRFGTWKAPAIGIAVFTGLFALSAFVIGPLFNPATSSDQDTPTPAASASTTGTEDHEGHHSPSPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ62</accession>
    <name>A0A1Q2CJ62_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_12820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12820"/>
    <dbReference type="EnsemblBacteria" id="AQP46159">
        <property type="protein sequence ID" value="AQP46159"/>
        <property type="gene ID" value="RPIT_12820"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12820"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP46159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="282" mass="30378" checksum="C45DAA2A9F217B40" modified="2017-04-12" version="1">MVTAAFEAGGGFVSPLYEAPWLGQWQGDPLLAHLRGDFVCVPFGMPGHGYAANHAWELLDVSDERAVLSIAYPEDHPVERVTREVVCADGALEFADSIEMREPASLPLGLHPMFRLPDGVGEARLVLPDAAAILTPPQPPEPTARLLPGQRFIDPTRAPSVDGTADLTRLPWEGRSEDLAQLVDVVEGRVGLVVDGVTTVLEWDQTVLKHCLLWVSNRGRDYPPWNGRNLCLGVEPVTSAFDLGAEASAGRNPVADEGVQTAVSLEPGETHVVHHRVSVTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ81</accession>
    <name>A0A1Q2CJ81_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bac_transf domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_13885</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13885"/>
    <dbReference type="EnsemblBacteria" id="AQP46179">
        <property type="protein sequence ID" value="AQP46179"/>
        <property type="gene ID" value="RPIT_13885"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13885"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_transf" evidence="3">
        <location>
            <begin position="7"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP46179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="215" mass="23827" checksum="E74BB862D65FDB91" modified="2017-04-12" version="1">MYNRFGKRFIDLVLVVPMIIILAPVLLAIAAAVFLTSGSPVLYQGERGGLHGKPFRILKFRTMVRNADQVGGGTTALGDARITRVGAVLRKTKLDEFPQLFNILRGEMSFIGPRPELLQYTSQYSGLEEYILEVRPGITDFSSLEFMNLASVVGSGDADAVYEREVLPRKNQLRIKYVARLSPVTDLRLFVHTVLRAVQGVMRHVFPGGGSHGDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBG1</accession>
    <name>A0A1Q2CBG1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ISL3 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_00215</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43438">
        <property type="protein sequence ID" value="AQP43438"/>
        <property type="gene ID" value="RPIT_00215"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00215"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002560">
        <property type="entry name" value="Transposase_DDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032877">
        <property type="entry name" value="Transposase_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029261">
        <property type="entry name" value="Transposase_Znf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01610">
        <property type="entry name" value="DDE_Tnp_ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13542">
        <property type="entry name" value="HTH_Tnp_ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14690">
        <property type="entry name" value="zf-ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-ISL3" evidence="3">
        <location>
            <begin position="23"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_Tnp_ISL3" evidence="2">
        <location>
            <begin position="78"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_ISL3" evidence="1">
        <location>
            <begin position="165"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="415" mass="46761" checksum="0D0AEAC76A16CBC3" modified="2017-04-12" version="1">MVGVHRDDAGLRVEVESRPPAVMGCPACGVIAHAHGRQRVELIDAPCFTAPVKLRWRKRRWLCPEPMCPVTSFMEQDPDVARPRALLTARATSWAIGQMRRENASVQGMARQLGCTWRTLWRAVKPILETAAADETRFVGVTSLGVDEHIWHHVSTKPVDQGGRGPKEFTGMVDLTRDKDGRVRARLLDLVPGRSGEAYTSWLRDRGDTFRKGVEIATLDPFHGYKNAIDDQLDDVIAVLDAFHVVKLGTAAVDEVRRRVQQDIHGHRGRRDDPLYRIRNLLRAGKEHLTDRQKTRLETAFSVDDRHVEVEVAWHCAQQLRSVYHQSNHADGRRVAEKILASFPSCPIPEIARLGRTLNRWRDALLGYFTTGGANNGGTEAINGLIELARRVARGFRNPDNYRLRMLLIGDGLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBG3</accession>
    <name>A0A1Q2CBG3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Ornithine carbamoyltransferase</fullName>
            <shortName evidence="6">OTCase</shortName>
            <ecNumber evidence="3 6">2.1.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_00340</name>
        <name evidence="11" type="ORF">SAMN05428934_10522</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>carbamoyl phosphate + L-ornithine = H(+) + L-citrulline + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19513"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.3" evidence="3 6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY83983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00340"/>
    <dbReference type="EnsemblBacteria" id="AQP43453">
        <property type="protein sequence ID" value="AQP43453"/>
        <property type="gene ID" value="RPIT_00340"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY83983">
        <property type="protein sequence ID" value="SDY83983"/>
        <property type="gene ID" value="SAMN05428934_10522"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00340"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004585">
        <property type="term" value="F:ornithine carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01109">
        <property type="entry name" value="OTCase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002292">
        <property type="entry name" value="Orn/put_carbamltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024904">
        <property type="entry name" value="OTCase_ArgI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00102">
        <property type="entry name" value="OTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="6"/>
            <end position="146"/>
        </location>
    </feature>
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        <location>
            <begin position="155"/>
            <end position="327"/>
        </location>
    </feature>
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        <location>
            <begin position="55"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="6">
        <location>
            <begin position="133"/>
            <end position="136"/>
        </location>
    </feature>
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        <location>
            <begin position="234"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="6">
        <location>
            <begin position="272"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
        </ligand>
    </feature>
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        <location>
            <position position="230"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:46911"/>
        </ligand>
    </feature>
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        <location>
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        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00001065"/>
        </source>
    </evidence>
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        <source>
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        <source>
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        </source>
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    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP43453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY83983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="330" mass="36317" checksum="6960D21074EBCC48" modified="2017-04-12" version="1">MSLTGRSFLKELDFTPEEWRGLLDLAAELKRERREGRETKRLAGKQVALLFEKTSTRTRCAFEVAVADQGGTTTYLDPAGSQIGHKESAADTARVLGRWYDALEYRGYRQDVVETLAAHAGVPVYNGLTDEWHPTQMLADQLTMLEHSDKPIGEIAFAFVGDARNNVGNSLLISGALMGMDVRMVAPESLQNAAEIVAQARHLAERTGARITITDDVASGVAGVDFVYTDVWVSLGEPKEVWAERIELLRDYQVNAELMAKTGNAHAKFMHCLPAFHDLETTVGRDLHAAFGLNGVEVTDDVFESPANIAFDQAENRMHTIKAILVATLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBI9</accession>
    <name>A0A1Q2CBI9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase C56</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Protease I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00440</name>
        <name evidence="4" type="ORF">SAMN05428934_10542</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C56 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00440"/>
    <dbReference type="EnsemblBacteria" id="AQP43471">
        <property type="protein sequence ID" value="AQP43471"/>
        <property type="gene ID" value="RPIT_00440"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY84550">
        <property type="protein sequence ID" value="SDY84550"/>
        <property type="gene ID" value="SAMN05428934_10542"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00440"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006286">
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR42733">
        <property type="entry name" value="PTHR42733"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="2">
        <location>
            <begin position="7"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00008542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY84550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="180" mass="19313" checksum="5683E8B6CC1916A7" modified="2017-04-12" version="1">MSTLDGKKIAFISVRGVEQPELTEPWQAVQEAGGQPVLISDKPGTITALKGDWDRGDDFPVDLTLDDADPDDFDALVLPGGTLNADEVRQSEKAQAFVRAFMEAGKPVAPICHGAWVLVEIDAVRGRRMTSTGAISTDLKNAGADWVDEEFVSDGNLLTSRNPDDLPAFNEGIVKAFAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBM8</accession>
    <name>A0A1Q2CBM8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Sugar (Pentulose or hexulose) kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00645</name>
        <name evidence="4" type="ORF">SAMN05428934_10582</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY85609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00645"/>
    <dbReference type="EnsemblBacteria" id="AQP43508">
        <property type="protein sequence ID" value="AQP43508"/>
        <property type="gene ID" value="RPIT_00645"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY85609">
        <property type="protein sequence ID" value="SDY85609"/>
        <property type="gene ID" value="SAMN05428934_10582"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00645"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07778">
        <property type="entry name" value="FGGY_L-RBK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042029">
        <property type="entry name" value="L-RBK-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="1">
        <location>
            <begin position="13"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="2">
        <location>
            <begin position="273"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY85609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="527" mass="55383" checksum="1801E97EBCCA7B6D" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBQ6</accession>
    <name>A0A1Q2CBQ6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00810"/>
    <dbReference type="EnsemblBacteria" id="AQP43537">
        <property type="protein sequence ID" value="AQP43537"/>
        <property type="gene ID" value="RPIT_00810"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00810"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="159"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="340" mass="36754" checksum="E85E2F6468C22B2A" modified="2017-04-12" version="1">MLHERALLALKSGLAAGLGWVVGAQFPGVMAEYAYYASLGGISVIYPAISDSVREAIRATAAIILGALVAALMQIISWPNALTVGLVVVIGTALGGLRFLGEQRHWVATAALFVLIFSGDPPQDYILIYVGQILTGALIGLAVNAAVPKMNLTSLSDAAEGLRAELVVQLRRVAELLRERDEPDAEQLEAVFDEIDNERDRLRQALEKVKRSTEGNPRAVRYEGVRRSLQDRARSLAHIAFMVQDVGVVLQDVQRDDYRVLDLQLRRATATAFAGLADVIETPTAELAERVRADVTDLMNQVHNAEFDDVEGRYLAGIIAASAQLSLSTALSSLPVVEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBT4</accession>
    <name>A0A1Q2CBT4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATPase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Potassium uptake protein, TrkH family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_00630</name>
        <name evidence="9" type="ORF">SAMN05428934_10579</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY85521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00630"/>
    <dbReference type="EnsemblBacteria" id="AQP43505">
        <property type="protein sequence ID" value="AQP43505"/>
        <property type="gene ID" value="RPIT_00630"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY85521">
        <property type="protein sequence ID" value="SDY85521"/>
        <property type="gene ID" value="SAMN05428934_10579"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00630"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003445">
        <property type="entry name" value="Cat_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02386">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="378"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP43505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY85521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="445" mass="47467" checksum="253823F6C64CB23E" modified="2017-04-12" version="1">MLTALRRLSPLRAILVAFTTAVWVGVGLLMLPIAKRGPGGASFLEAFFTATSAICVTGLTTVDTEHYWTPFGQVIIMLLIQVGGFGVMTLATFIGFAVLGKLSLRSKLTAATEAHTAGPGGLGEVLKGIVLASLLIESVTAATLTLRFWVGYPYSLPEAAWRGVFHAVSSFNNAGFALYSDNIMRFVGDPWICLPLAAATILGGLGFPVLLQLKRCGIDVMRWSMNTRLVIVLSPILLLGGWLFIGVLEWSNPGTLGPLSWPDKLLASFFHSVQTRTSGFNSVDIGAMHGATRLGMDVLMFIGGGPAGTAGGIKVTTFAVLFFIIWTELRGDTAVHIFGKRLSRAVHRQAISVALLAVALVVMSTMALLLLTPFTLDVVLFQVVSSFGTVGLSTGITAALDPVSQLVLCFLMYVGRLGPITFASALALTPRRRLFELPKERPIIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBT7</accession>
    <name>A0A1Q2CBT7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PadR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, PadR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01010</name>
        <name evidence="3" type="ORF">SAMN05428934_105153</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01010"/>
    <dbReference type="EnsemblBacteria" id="AQP43574">
        <property type="protein sequence ID" value="AQP43574"/>
        <property type="gene ID" value="RPIT_01010"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87515">
        <property type="protein sequence ID" value="SDY87515"/>
        <property type="gene ID" value="SAMN05428934_105153"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01010"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="20"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY87515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="117" mass="12676" checksum="5C62B0F1285AC7B1" modified="2017-04-12" version="1">MDTDIAWPSEWLRGVLGVCVLRILSDGPTYGYEIATRLAAAGLGTVKGGTLYPLLGRFEETGWVEVEWRPGDGGPGRKYYALTDAGRSEAAAVAARWAQFTDTTRLLTDPLISSRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBZ2</accession>
    <name>A0A1Q2CBZ2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidoglycan glycosyltransferase</fullName>
            <ecNumber evidence="1">2.4.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_01360</name>
        <name evidence="12" type="ORF">SAMN05428934_10819</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01360"/>
    <dbReference type="EnsemblBacteria" id="AQP43629">
        <property type="protein sequence ID" value="AQP43629"/>
        <property type="gene ID" value="RPIT_01360"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01260">
        <property type="protein sequence ID" value="SDZ01260"/>
        <property type="gene ID" value="SAMN05428934_10819"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01360"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 12" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transgly" evidence="10">
        <location>
            <begin position="72"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="9">
        <location>
            <begin position="359"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="763"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="767"/>
            <end position="801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP43629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDZ01260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="810" mass="87049" checksum="B4889BBEFB7399A8" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC24</accession>
    <name>A0A1Q2CC24_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nitrogen regulatory protein P-II family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01510</name>
        <name evidence="4" type="ORF">SAMN05428934_10850</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01510"/>
    <dbReference type="EnsemblBacteria" id="AQP43652">
        <property type="protein sequence ID" value="AQP43652"/>
        <property type="gene ID" value="RPIT_01510"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01882">
        <property type="protein sequence ID" value="SDZ01882"/>
        <property type="gene ID" value="SAMN05428934_10850"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01510"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002187">
        <property type="entry name" value="N-reg_PII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002332">
        <property type="entry name" value="N-reg_PII_urydylation_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30115">
        <property type="entry name" value="PTHR30115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00543">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00340">
        <property type="entry name" value="PIIGLNB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00938">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51343">
        <property type="entry name" value="PII_GLNB_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00496">
        <property type="entry name" value="PII_GLNB_UMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="O-UMP-tyrosine" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR602187-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ01882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="112" mass="12114" checksum="5B5DAE00137D54A2" modified="2017-04-12" version="1">MRLVTAIVQPTMLTNVQIALARHGIAGMTVTECSGYARQRGHREVYRGAEYTIDFIAKVKIEVLVEDEETEAVIDVITAAARTGAVGDGKVWSTLVDEVVRIRTGERGAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC29</accession>
    <name>A0A1Q2CC29_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA-binding transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01650</name>
        <name evidence="3" type="ORF">SAMN05428934_10879</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43673">
        <property type="protein sequence ID" value="AQP43673"/>
        <property type="gene ID" value="RPIT_01650"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02411">
        <property type="protein sequence ID" value="SDZ02411"/>
        <property type="gene ID" value="SAMN05428934_10879"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01650"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00552">
        <property type="entry name" value="HTH_MERR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ02411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="358" mass="38357" checksum="32841A853254B37C" modified="2017-04-12" version="1">MEWLRIGEVAARTGLTPRTLRHYDELGLLVPSGRTDGDYRLYSRDDMDRLLAIQHLKSLGLGLAEIQQALDDPTFDAGPLLERHARVVEQRIAAEQALLRRLRQLQTAAQTGWDEVLETIALSERLRHPDGEVRFRAALTGHASAPVEDLVERLRSDPEPGVREAATWALAQQGPAALRAVSSLADGDAQARHALAHVLGKLRTIEALPQLSLLLTDDVPEVAAKAAFSLGQVGGDEAVQLLIGALEDGRVAVRDEATSALGRLPESLASLTAAASHPLPQVRAQVAEALGFLAHPEAVPVLIAALEDDDADVRFSALLALGSAEGPEARHALEALTASPDRRTSLVAARLLEARPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC94</accession>
    <name>A0A1Q2CC94_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Acyl-coenzyme A oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_01915</name>
        <name evidence="11" type="ORF">SAMN05428934_11621</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-CoA oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000016">
        <property type="protein sequence ID" value="SDZ20507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01915"/>
    <dbReference type="EnsemblBacteria" id="AQP43717">
        <property type="protein sequence ID" value="AQP43717"/>
        <property type="gene ID" value="RPIT_01915"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ20507">
        <property type="protein sequence ID" value="SDZ20507"/>
        <property type="gene ID" value="SAMN05428934_11621"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01915"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003997">
        <property type="term" value="F:acyl-CoA oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012258">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002655">
        <property type="entry name" value="Acyl-CoA_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909">
        <property type="entry name" value="PTHR10909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01756">
        <property type="entry name" value="ACOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000168">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="9">
        <location>
            <begin position="24"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="8">
        <location>
            <begin position="132"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="275"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="ACOX" evidence="7">
        <location>
            <begin position="496"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP43717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDZ20507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="642" mass="70331" checksum="64342988A73E2756" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCA4</accession>
    <name>A0A1Q2CCA4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate ABC transporter substrate-binding protein, CUT1 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Maltose ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02085</name>
        <name evidence="3" type="ORF">SAMN05428934_10114</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY22718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02085"/>
    <dbReference type="EnsemblBacteria" id="AQP43748">
        <property type="protein sequence ID" value="AQP43748"/>
        <property type="gene ID" value="RPIT_02085"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY22718">
        <property type="protein sequence ID" value="SDY22718"/>
        <property type="gene ID" value="SAMN05428934_10114"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02085"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544402" evidence="1">
        <location>
            <begin position="25"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY22718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="423" mass="43736" checksum="F0385E54C997D915" modified="2017-04-12" version="1">MRKSLFAAAAVGLSLTLVACGGDASETTTTPTPTDTATAVATETTTASETAAPGAAGTLTIWVDDTRVDAFKTLGEDFLAQTGVTLDVVQKPTGDIKTDFIAQAPTGEGPDLIVTAHDAIGDLVSNGVISAVELGDKVDAFSDVATRAVSLEGTMYAVPYGVENIGLVRNNALVQDTPATFDELIAQGKAVEGAEFPIVIQQGEGGDPYHLYPLQTSFGAPVFKTDENGDYIGELAMGGAEGEAFATYMKKLVDEGVLSASIGGDQAKQAFLDGKSPYMITGPWNTTEFAAAGMDISVLPVPSAGGQPAAPFVGVQAVFASSQSENPLLANQFLDYMASKEAQDKMYELRGLMPALTESADAVEDEILAGFAEAGAQGEPMPGIPQMGAVWTFWGNGQVAILTGAAEPVPAWQDMIANIEGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCB5</accession>
    <name>A0A1Q2CCB5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_02025</name>
        <name evidence="2" type="ORF">SAMN05428934_1012</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY22364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43737">
        <property type="protein sequence ID" value="AQP43737"/>
        <property type="gene ID" value="RPIT_02025"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY22364">
        <property type="protein sequence ID" value="SDY22364"/>
        <property type="gene ID" value="SAMN05428934_1012"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02025"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY22364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="143" mass="15626" checksum="AE33C3CFF595B94C" modified="2017-04-12" version="1">MVRQDLADLIRERRIETVARDPEQVALLREQARAHLQSSRMIGHTDPAGAFSLAYDSIRKQLTALLLDHGFRAKSAGSHAATGQAAAKLLKGFDTDGFEWLRLVRNATAYGSDKQPPAGLADLEDAWEFASELDALLPPITSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCC4</accession>
    <name>A0A1Q2CCC4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Polyphosphate kinase</fullName>
            <ecNumber evidence="6 7">2.7.4.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-polyphosphate phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Polyphosphoric acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ppk</name>
        <name evidence="12" type="ORF">RPIT_01780</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>[phosphate](n) + ATP = [phosphate](n+1) + ADP</text>
            <dbReference type="Rhea" id="RHEA:19573"/>
            <dbReference type="Rhea" id="RHEA-COMP:9859"/>
            <dbReference type="Rhea" id="RHEA-COMP:14280"/>
            <dbReference type="ChEBI" id="CHEBI:16838"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="6 7">An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the polyphosphate kinase 1 (PPK1) family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.1" evidence="6 7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01780"/>
    <dbReference type="EnsemblBacteria" id="AQP43695">
        <property type="protein sequence ID" value="AQP43695"/>
        <property type="gene ID" value="RPIT_01780"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01780"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009358">
        <property type="term" value="C:polyphosphate kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1840.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00347">
        <property type="entry name" value="Polyphosphate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003414">
        <property type="entry name" value="PP_kinase"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF02503">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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        <location>
            <begin position="14"/>
            <end position="120"/>
        </location>
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            <begin position="130"/>
            <end position="324"/>
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            <end position="501"/>
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            <begin position="509"/>
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        <ligand>
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            <position position="381"/>
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        <ligand>
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            <dbReference type="Proteomes" id="UP000188324"/>
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    </evidence>
    <sequence length="695" mass="78125" checksum="DE22999D77029B96" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
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                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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    </dbReference>
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        <location>
            <begin position="6"/>
            <end position="154"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY22980.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="184" mass="19080" checksum="9FCA02195E269C7F" modified="2017-04-12" version="1">MTVRHAVVLGGGRSSRMGADKLALRLEGESLLARACAAALTFADHVVVAGPEREGVPDGISFVREDPPFSGPAAGLAAALDALPAGDEVLVLAGDLALPQSAVDLLAAEALEGDGVVLRDEEGWPQYLCGRYRQEPLTRALAGDVRDVAVRRLLGPLNLAILSAPKSVTEDLDTPGQAQRLGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCI4</accession>
    <name>A0A1Q2CCI4_9ACTN</name>
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        </recommendedName>
        <alternativeName>
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        </alternativeName>
        <alternativeName>
            <fullName evidence="11 12">AIRS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 12">Phosphoribosyl-aminoimidazole synthetase</fullName>
        </alternativeName>
    </protein>
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        <name evidence="12" type="primary">purM</name>
        <name evidence="15" type="ORF">RPIT_02385</name>
        <name evidence="16" type="ORF">SAMN05428934_10175</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1T</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1</strain>
        </source>
    </reference>
    <reference evidence="15" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 12">
            <text>2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23032"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 12">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the AIR synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.1" evidence="3 12"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY24544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02385"/>
    <dbReference type="EnsemblBacteria" id="AQP43807">
        <property type="protein sequence ID" value="AQP43807"/>
        <property type="gene ID" value="RPIT_02385"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY24544">
        <property type="protein sequence ID" value="SDY24544"/>
        <property type="gene ID" value="SAMN05428934_10175"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02385"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00129"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004641">
        <property type="term" value="F:phosphoribosylformylglycinamidine cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02196">
        <property type="entry name" value="PurM"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00741">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004733">
        <property type="entry name" value="PurM_cligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10520">
        <property type="entry name" value="PTHR10520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00878">
        <property type="entry name" value="purM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRS" evidence="13">
        <location>
            <begin position="59"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="14">
        <location>
            <begin position="175"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="AQP43807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="SDY24544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="346" mass="35760" checksum="755C90361BCD3C93" modified="2017-04-12" version="1">MNQSAYAAAGVDIEAGDRAVELMKASVGRARRPEVLGGLGGFAGFFDASALKGYDHPVLATSTDGVGTKVAIAQAMDKHDTIGFDLIGMLVDDLVVCGAEPLFVTDYIACGKVVPERIAAIVGGIADACVASGAALVGGETAEHPGLLEPHEYDIAGATTGVVERSKMLGSDRIRIGDAVIAMASSGLHSNGYSLVRHVLLDQAGWSLDRQIDELGRTLGEELLEPTKIYALDVLDLIGKVEVHALSHITGGGLANNLARVIPGDMVAVLQRSSWTPPPVFDLVQRVGGISQRDIEATLNMGVGMVAVLPPDQVDGALSALAARGVDGWTIGEIQALEGPGTAVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCW3</accession>
    <name>A0A1Q2CCW3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-keto-myo-inositol dehydratase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Inosose dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03315</name>
        <name evidence="3" type="ORF">SAMN05428934_101264</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03315"/>
    <dbReference type="EnsemblBacteria" id="AQP43963">
        <property type="protein sequence ID" value="AQP43963"/>
        <property type="gene ID" value="RPIT_03315"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30251">
        <property type="protein sequence ID" value="SDY30251"/>
        <property type="gene ID" value="SAMN05428934_101264"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03315"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="43"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY30251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="311" mass="35040" checksum="E090427E1AB78E27" modified="2017-04-12" version="1">MTQIDKSRNPDPRYNKLTVGVCPDQWGVWFPEDPLQIPWEKALDEMAEAGFSVMETGPFGYFPTDPKRLSEEMAKRGFRVVAGTAWGVLHQEDAWAATEELFRRVGETHAAVGAEYVVHLPPMFRDEHTGDFTDVRHLDGAAWDLYVNNANRLGKMMKDDYGLKLVLHPHGDSHIETRDDIDRIFQATDPEYVGFCLDTGHIVYGMGDNIDLIRTYPDRISYVHIKAMDPAIVKQAHDEDWPFVKAVKAGCSVPPPEGEPDMPSLVEALADLDKELYVICEQDMYGCDPSYPLPNAIKVREYLASIGLGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCW5</accession>
    <name>A0A1Q2CCW5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methylmalonate-semialdehyde dehydrogenase (CoA acylating)</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Methylmalonate-semialdehyde dehydrogenase [acylating]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_03285</name>
        <name evidence="4" type="ORF">SAMN05428934_101258</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03285"/>
    <dbReference type="EnsemblBacteria" id="AQP43958">
        <property type="protein sequence ID" value="AQP43958"/>
        <property type="gene ID" value="RPIT_03285"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30055">
        <property type="protein sequence ID" value="SDY30055"/>
        <property type="gene ID" value="SAMN05428934_101258"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03285"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004491">
        <property type="term" value="F:methylmalonate-semialdehyde dehydrogenase (acylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07085">
        <property type="entry name" value="ALDH_F6_MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010061">
        <property type="entry name" value="MeMal-semiAld_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866">
        <property type="entry name" value="PTHR43866"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01722">
        <property type="entry name" value="MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="2">
        <location>
            <begin position="20"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY30055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="498" mass="53304" checksum="907A56E99CA97956" modified="2017-04-12" version="1">MTQTITHWIGGAPYEGSPDHRIPVENPASGKVEGELLSASAADLDHAVEVAREALKIWSKTSLAKRTAIMFKMRELVLANQDELAKAIVNEHGKDYNDAIGEIQRGRETLDFACGINAALKGEFSYDISTGVDIHTVRQPVGVVAGVCPFNFPVMVPMWMHPVAIATGNTFILKPASPTPTASLLVAKLYKEAGLPDGVFNVVAGDRDIVTNILEHPGINAISFVGSTPVARIIQEKGTANGKRVQALGGANNHAIVMPDADLAFAAQHISAAAFGAAGERCMALPVVVAVGGVGPKLAELVKEHAQKIKVGYGLDEGVQMGPVITRKAQERIKAIITDAEERGASVVLDGRDIKVDGYEDGFWVGPTVLDDVPLDAPAYHEEVFGPVLTIVHADTYQEAIDQVNSSEYGNGAAIFTNDGGVARRFELDVEAGMVGVNVPIPTPVAYYSFGGWKDSLLGDTHIHGPEGVKFYTKLKAITSRWPSERTFEATMSFMREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD28</accession>
    <name>A0A1Q2CD28_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Na+/H+-dicarboxylate symporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Sodium:proton antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_03545</name>
        <name evidence="8" type="ORF">SAMN05428934_101310</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY31626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03545"/>
    <dbReference type="EnsemblBacteria" id="AQP44001">
        <property type="protein sequence ID" value="AQP44001"/>
        <property type="gene ID" value="RPIT_03545"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY31626">
        <property type="protein sequence ID" value="SDY31626"/>
        <property type="gene ID" value="SAMN05428934_101310"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03545"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PTHR42865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY31626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="450" mass="46992" checksum="CEA277FDFBAFDF34" modified="2017-04-12" version="1">MSTSLSERRSERAVEPRKPFYTGLGFQIIVGLIAGLILGLVALSLGPTADGERNWLTTTLSEVGSAYVKLLMLLVVPLVVTAVISSISRLTQVANAARLAVQTLLWFAITALASVIVGILVGVFSAPWLTAGVSGDAAAEPSRVGSWTAFILGIIPSNFLGLGVNASASGEGAVTASPSFSVLQILFVSILFGIAAVKVGDKAAPFIGFMESALSVIQKVLWWIIRLAPIGTAALIGRAVATYGWSSLASLGAFVVALYVGLAIVWLVVYPTILKLNGLGVRQFYRNAWPAITLGFFTRSSMGTMPVTEQVIERNLGVERGYASFVAPLGATTKMDGCASVFPAIAAIFVANFYGIDLNVTHYLLIAFVAVLGSAATAGTTGATVMLTLTLSTLGLPLEGVGLLLAVEPIIDMGRTALNVTGQALVPTIVGKREKVLDRGIYDAKPVFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD67</accession>
    <name>A0A1Q2CD67_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SCP_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03505"/>
    <dbReference type="EnsemblBacteria" id="AQP43995">
        <property type="protein sequence ID" value="AQP43995"/>
        <property type="gene ID" value="RPIT_03505"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03505"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041629">
        <property type="entry name" value="SCP_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17844">
        <property type="entry name" value="SCP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP_3" evidence="1">
        <location>
            <begin position="52"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="140" mass="14631" checksum="7541CE0241885447" modified="2017-04-12" version="1">MFKPSPAVVAALRARFEDHAELDAVLAGRRPDLTGLLLQAAQAPEPLGAVLLAAVARAGCSLLGERHPGASIEVRVPPYAAVQIGFDSGPRHTRGTPPNVVEMDPETFAALAAGRLDWAEAPLRASGAHAAETERAFPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD68</accession>
    <name>A0A1Q2CD68_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_03875</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03875"/>
    <dbReference type="EnsemblBacteria" id="AQP44059">
        <property type="protein sequence ID" value="AQP44059"/>
        <property type="gene ID" value="RPIT_03875"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03875"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="35"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="312"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="405" mass="41925" checksum="4DE4D1031857A97A" modified="2017-04-12" version="1">MAWSTMVEIQRSRVQTTALLNEAIAGITQRPGRAVLTALGTVIGIAVLIAILGLTSSASVQVSKAFSLVEATEVRVTQEVTSIGSRIDALAFPLNAGDRAKAITGVRNAGLRWHLQQSVSNPPSTRTIELPFAASAGFLETAGATYSQGRGFDTGHEERTARVAVMGIGAANDLGISDISRSPAVIIGGAWFTVIGIIDDTQRLPELLSAVVVPMTTAHVLWHDPMPEMQVDLVVDVEPGAGPIVGQQLPLAMSATHPNRFSVTLPPDPTSLRETVDAQLSGLFLVLAVVCLVVGMVGIANTTVVAVMERTGEIGLRRAMGALPRHIAAQFLVEASVLGALGGLTGTSIGVVTVVIACSVLGWTAVISPLLVILGPLVGLVAGAVAGIYPSLRAASLEPVDALRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD83</accession>
    <name>A0A1Q2CD83_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44056">
        <property type="protein sequence ID" value="AQP44056"/>
        <property type="gene ID" value="RPIT_03860"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03860"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013156913" evidence="1">
        <location>
            <begin position="26"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="304" mass="33619" checksum="2872CEFFA737C3D9" modified="2017-04-12" version="1">MVFRGACAALLVVALAGCVPEVGSRPPNERVGATPATTGLTPVTSESQLVLPLDRYQTTVDEWRLIMDSQQHARVECMGRFGLETRPERFEPDLYEDVYDSGHLRYGLFDREAVEENGYGSGESSLVDDAIEIPITDDVRRFKELLLGTDAVGNPVAAVDVSGVPLPKGGCNAEVQQRLTDGVTADAAFLDLPNKLSSEAQEELLSSQEFAALEAEWSECMAESGYEFVHRWDAEESVLRESPARQREMALEDLECGERTNFVARMMSLDAAIQERLIAENEASLRGALEMKRKLLENAKELFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDF6</accession>
    <name>A0A1Q2CDF6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Cell division protein FtsZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ftsZ</name>
        <name evidence="11" type="ORF">RPIT_04045</name>
        <name evidence="12" type="ORF">SAMN05428934_101412</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="6">Assembles at midcell at the inner surface of the cytoplasmic membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the FtsZ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY34427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04045"/>
    <dbReference type="EnsemblBacteria" id="AQP44085">
        <property type="protein sequence ID" value="AQP44085"/>
        <property type="gene ID" value="RPIT_04045"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY34427">
        <property type="protein sequence ID" value="SDY34427"/>
        <property type="gene ID" value="SAMN05428934_101412"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04045"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051258">
        <property type="term" value="P:protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02201">
        <property type="entry name" value="FtsZ_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00909">
        <property type="entry name" value="FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000158">
        <property type="entry name" value="Cell_div_FtsZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020805">
        <property type="entry name" value="Cell_div_FtsZ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024757">
        <property type="entry name" value="FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12327">
        <property type="entry name" value="FtsZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00423">
        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="SSF55307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00065">
        <property type="entry name" value="ftsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01134">
        <property type="entry name" value="FTSZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01135">
        <property type="entry name" value="FTSZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 6 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0717">Septation</keyword>
    <feature type="domain" description="Tubulin" evidence="9">
        <location>
            <begin position="11"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin_C" evidence="10">
        <location>
            <begin position="205"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="315"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="326"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="19"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="106"/>
            <end position="108"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY34427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="387" mass="40217" checksum="D78649FD2727D4D6" modified="2017-04-12" version="1">MASASQNYLAVIKVVGVGGGGVNAINRMIEAGLRGVEFIAVNTDAQALLMSDADVKLDIGRELTRGLGAGADPAKGRQAAEDHSDDIEEALKGADMVFVTAGEGGGTGTGAAPIVAKIARSIGALTIGVVTRPFSFEGRRRATQAETGIESLREEVDTLIVIPNDKLLQMTDHQVAILDAFKQADQVLMQGVSGITDLITTPGLINLDFADVKSIMSQAGSALMGIGSARGEDRARAAAEMAISSPLLEASIDGAHGVLLSIAGGSDLGLFEVSAAAQLIEEAAHDEANIIFGTVIDDALGDEVRVTVIAAGFDGGQPLKRQSRPAERPQPQQSRPAPQQAQPQQPRQQAQPAAPQANPMPGQRPAQPAPVAPQYDDDDLDVPDFMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDI6</accession>
    <name>A0A1Q2CDI6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fe-S cluster assembly ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Fe-S cluster assembly ATPase SufC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_04355</name>
        <name evidence="7" type="ORF">SAMN05428934_101476</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. Ycf16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY36289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04355"/>
    <dbReference type="EnsemblBacteria" id="AQP44140">
        <property type="protein sequence ID" value="AQP44140"/>
        <property type="gene ID" value="RPIT_04355"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY36289">
        <property type="protein sequence ID" value="SDY36289"/>
        <property type="gene ID" value="SAMN05428934_101476"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04355"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03217">
        <property type="entry name" value="ABC_FeS_Assembly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010230">
        <property type="entry name" value="FeS-cluster_ATPase_SufC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43204">
        <property type="entry name" value="PTHR43204"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01978">
        <property type="entry name" value="sufC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY36289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="254" mass="27603" checksum="CDFE44D7C87E30F6" modified="2017-04-12" version="1">MSTLVISDLHVDVLTEDGPKQILKGVNLTINPGEIHALMGPNGSGKSTLAYAIAGHPKYEITQGSVTLDGQELTEMSVDERAKAGLFLAMQYPVEVPGVSVANFLRTAKTALDGEAPKVRTWVKDVEKALGQMQLDKSFSGRSVNEGFSGGEKKRHEIAQLELLNPKAAILDETDSGLDIDALRVVSDGVNRFAEKGDRAIVLITHYTRILRYIEPTFVHVFVDGRIVAEGGKELADQLEADGYERYIREAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDI8</accession>
    <name>A0A1Q2CDI8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Proline--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Prolyl-tRNA synthetase</fullName>
            <shortName evidence="8">ProRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">proS</name>
        <name evidence="10" type="ORF">RPIT_04555</name>
        <name evidence="11" type="ORF">SAMN05428934_101517</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04555"/>
    <dbReference type="EnsemblBacteria" id="AQP44174">
        <property type="protein sequence ID" value="AQP44174"/>
        <property type="gene ID" value="RPIT_04555"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37317">
        <property type="protein sequence ID" value="SDY37317"/>
        <property type="gene ID" value="SAMN05428934_101517"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04555"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00861">
        <property type="entry name" value="ProRS_anticodon_short"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ProRS_core_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01569">
        <property type="entry name" value="Pro_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
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        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
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        <property type="entry name" value="Pro-tRNA-synth_IIa_bac-type"/>
    </dbReference>
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        <property type="entry name" value="Pro-tRNA-Synthase_IIa_type1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00409">
        <property type="entry name" value="proS_fam_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
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    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 10" id="KW-0436">Ligase</keyword>
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    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="9">
        <location>
            <begin position="35"/>
            <end position="490"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00000857"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY37317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="591" mass="64238" checksum="8D86696E618063C7" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDJ6</accession>
    <name>A0A1Q2CDJ6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyltransferase (GNAT) family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04625</name>
        <name evidence="3" type="ORF">SAMN05428934_101531</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY37655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44188">
        <property type="protein sequence ID" value="AQP44188"/>
        <property type="gene ID" value="RPIT_04625"/>
    </dbReference>
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        <property type="gene ID" value="SAMN05428934_101531"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04625"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="3"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY37655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="159" mass="17597" checksum="44C555821BC8085B" modified="2017-04-12" version="1">MAISVRPAEAADLDQLRAKQARPELGLVDKHFEAQEDGTLIYAVAFEDGEPLGTAILDLSEGQMMPELRNMYVYPEARRRGAGRALTTYIEELARQAGHAAVYLAVDPNNAKAVPLYVSLEYYPTGEHLFVEAPEIDQVDDGQQASTHYAIYKKSLTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDK0</accession>
    <name>A0A1Q2CDK0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal silencing factor RsfS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rsfS</name>
        <name evidence="3" type="ORF">RPIT_04700</name>
        <name evidence="4" type="ORF">SAMN05428934_101548</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with ribosomal protein L14 (rplN).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Iojap/RsfS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY38048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04700"/>
    <dbReference type="EnsemblBacteria" id="AQP44202">
        <property type="protein sequence ID" value="AQP44202"/>
        <property type="gene ID" value="RPIT_04700"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY38048">
        <property type="protein sequence ID" value="SDY38048"/>
        <property type="gene ID" value="SAMN05428934_101548"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04700"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:mature ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090071">
        <property type="term" value="P:negative regulation of ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01477">
        <property type="entry name" value="Iojap_RsfS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004394">
        <property type="entry name" value="Iojap/RsfS/C7orf30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043">
        <property type="entry name" value="PTHR21043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00090">
        <property type="entry name" value="rsfS_iojap_ybeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY38048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="131" mass="14691" checksum="AE92B4770E3C526C" modified="2017-04-12" version="1">MTVSDDVLRPVRIAAQGAADKLGHNIVAFDVSEQLAITDVFLIASANTERQVGAIVDGVEEALLKHGYKALRREGDRENRWVLLDYVDFVVHVQHSEERTLYSLERLWKDCPQIPLDLDLPPAADPSDDEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDL3</accession>
    <name>A0A1Q2CDL3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MurNAc alpha-1-phosphate uridylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04770</name>
        <name evidence="3" type="ORF">SAMN05428934_101563</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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</entry>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    </comment>
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    </dbReference>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="771" mass="78827" checksum="AF417F07E9DDA923" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="10" key="3">
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                <person name="Peterson S.W."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
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            <end position="90"/>
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    <feature type="transmembrane region" description="Helical" evidence="8">
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            <end position="117"/>
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    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
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        <location>
            <begin position="207"/>
            <end position="267"/>
        </location>
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        <location>
            <begin position="275"/>
            <end position="332"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY39604.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="438" mass="47632" checksum="6D01688DA71C6C06" modified="2017-04-12" version="1">MSQSEWIELGLALLCAIGASVLAAVEAALGGVTKARAERLVEQGVPGAERIRLIAQDPAPTINAVMFSRMLLEITSIVLVSIVMFTQFQVDWQRALVTTAIMLVVSFVLWGVAPRTLGKQQPEKTLRTFGALASGLTTVFGPVASLMILLGNALTPGRGYRDGPFATEAELRDLVDMAQASDLIEAGESKMIHSVFELGDTLVKEVMVPRPDVVFITADKTLRQLLSLALRSGFSRIPVIGEDLDDILGVIYLKDVSKRIYDFPDSERYETVAELMRPATFCPDSKPVSELLRDMQLSHSHLVVVVDEFGGTAGLATIEDILEEIVGEIVDEYDQDAPAVAELSDGRYRVSSRLSLDDLSSLFHVDIDDDDVETVGGLMAKQLNLVPIPGSRVVVRDLELVADRAVGRRHQIGTVIVRRLSPEELADDASHTEGSPDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE24</accession>
    <name>A0A1Q2CE24_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BFN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05740</name>
        <name evidence="3" type="ORF">SAMN05428934_10395</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05740"/>
    <dbReference type="EnsemblBacteria" id="AQP44374">
        <property type="protein sequence ID" value="AQP44374"/>
        <property type="gene ID" value="RPIT_05740"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67546">
        <property type="protein sequence ID" value="SDY67546"/>
        <property type="gene ID" value="SAMN05428934_10395"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05740"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.690.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036104">
        <property type="entry name" value="BFN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003729">
        <property type="entry name" value="Bi_nuclease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02577">
        <property type="entry name" value="DUF151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103256">
        <property type="entry name" value="SSF103256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51658">
        <property type="entry name" value="BFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BFN" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY67546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="153" mass="16485" checksum="A9DBBC552581155B" modified="2017-04-12" version="1">MIGLEVLGIRLVSPDDPPVLLLREREGTRSLPIWIGHAEAAAIASALEGEEPERPMTHDLLATVLELLGGSGHVEITAMAEGIYDASLHVGDHQIMARPSDCTAVALRLDWPIYCTPALMDQVGVEVDAPAADEVEAFRAFLDSVNADDFEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE31</accession>
    <name>A0A1Q2CE31_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TadE-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05765</name>
        <name evidence="3" type="ORF">SAMN05428934_103100</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05765"/>
    <dbReference type="EnsemblBacteria" id="AQP44379">
        <property type="protein sequence ID" value="AQP44379"/>
        <property type="gene ID" value="RPIT_05765"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67690">
        <property type="protein sequence ID" value="SDY67690"/>
        <property type="gene ID" value="SAMN05428934_103100"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05765"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012495">
        <property type="entry name" value="TadE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07811">
        <property type="entry name" value="TadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY67690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="140" mass="14093" checksum="56FC35FC0C2A4EF5" modified="2017-04-12" version="1">MRWDQRGLSVSVEAAVIIPVLLLFVGLVITSARVAIAEQHVGAAAAAGARAASLERTVGPAREAATTAAGRVLAQHGTPCRHTAVVVDSSGVARGLGERAAVGVTVQCSVDLSDVSLPGVPGTITVAASRNSPVDPLRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE81</accession>
    <name>A0A1Q2CE81_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05770"/>
    <dbReference type="EnsemblBacteria" id="AQP44380">
        <property type="protein sequence ID" value="AQP44380"/>
        <property type="gene ID" value="RPIT_05770"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05770"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="14"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="294" mass="31860" checksum="F04BFC6931C9CCE9" modified="2017-04-12" version="1">MNLQRRIGQHQVSPIGLGAMPLSMGGNQKPSEEQAIATVHAALDAGVTLIDTADIYAPSWDSMGHNERIVAKALRSYDGDTSRVRVATKAGITRGEGESWGRDSSPEYLRRRLEEALSTLGVDRLDLFYLHRPDRSRVYSTVMETFGTLKAEGLISEIGISNANVEEIRIAIDVLGEGELAAVQNEFSPKFNHTSKPELDFCAEHGIAFLPWSPLGGTGGAAKQLDSKYPVIARIAAERGVSPQQVTLAWELSLGSHVIPIPGASRPESITDSAKAMRLELSDEETQEISEAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEA0</accession>
    <name>A0A1Q2CEA0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_05875</name>
        <name evidence="6" type="ORF">SAMN05428934_103123</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05875"/>
    <dbReference type="EnsemblBacteria" id="AQP44400">
        <property type="protein sequence ID" value="AQP44400"/>
        <property type="gene ID" value="RPIT_05875"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68288">
        <property type="protein sequence ID" value="SDY68288"/>
        <property type="gene ID" value="SAMN05428934_103123"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05875"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="152"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY68288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="220" mass="23261" checksum="E477D1244BE5B0E2" modified="2017-04-12" version="1">MHTIRLVIIDDDALVRAGLGMLLGGGRSGFEIVGEGADGADAVPLVEAHRPDIVLMDIRMPRVDGVAATRQVLALPDPPKVIVLTTFSSDDLVVEALRAGAHGFLLKDTAPPEMVEAIRRAADGERALSPQVVSAVIAAATSHPGDERTRRARAELDGLSERELEVAVELGRGLSNAEIATKLYQSVATVKATVTRILAKLGCTNRTQVALLVHDADLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEE4</accession>
    <name>A0A1Q2CEE4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pimeloyl-ACP methyl ester carboxylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06030</name>
        <name evidence="3" type="ORF">SAMN05428934_103153</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY69040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06030"/>
    <dbReference type="EnsemblBacteria" id="AQP44425">
        <property type="protein sequence ID" value="AQP44425"/>
        <property type="gene ID" value="RPIT_06030"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY69040">
        <property type="protein sequence ID" value="SDY69040"/>
        <property type="gene ID" value="SAMN05428934_103153"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06030"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="3"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY69040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="229" mass="24861" checksum="1D28DE7CE6048719" modified="2017-04-12" version="1">MDIILIPGLWLDESSWDRVVPLLREAGHRVVAVNPPGHDGQDPSTVTYGDLVATVVNEIDHAHGRCLVVGHSAHCAAAWAAADRRVDQVAGVVLIGGFPIPDGSEILDGFEPSDGVLPFVGWDAFDGPDTADLDQQALAELEGAMSPAPAAYAVGPQHLQDERRYDLPVTLVCPEYTQQDLQAWAQSGAPHLSELSRLRRGRYVDLHSGHWPQWSMPRKLADVILDCTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEH2</accession>
    <name>A0A1Q2CEH2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidoglycan-binding (PGRP) domain of peptidoglycan hydrolases-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_06500</name>
        <name evidence="4" type="ORF">SAMN05428934_103245</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06500"/>
    <dbReference type="EnsemblBacteria" id="AQP44503">
        <property type="protein sequence ID" value="AQP44503"/>
        <property type="gene ID" value="RPIT_06500"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71472">
        <property type="protein sequence ID" value="SDY71472"/>
        <property type="gene ID" value="SAMN05428934_103245"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06500"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="SSF52129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PG_binding_1" evidence="2">
        <location>
            <begin position="318"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="2">
        <location>
            <begin position="412"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY71472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="467" mass="49179" checksum="799A300A1722C59A" modified="2017-04-12" version="1">MTGYSLHLGLNVVDPSQYIPAPAPLAGCINDARSMTDLAASQGFNTRTLLDAEATSWALLGALGDLARKATAGDIALITFAGHGGRVTDQNGDEDDSTDETWCLYDRQVLDDELYRMWAQFSPGVRILVVSDSCHSGTVARAVLAIAAREALVRNPLGQELWPVDVTVAPLRPRALPPSMAAADSERRRDLYRSVQELAGNTRSTDIAAQLILLAGCQDSQVASDGDTNGLFTEALLRTWSNGSFSGDYRAFHSRIQMQMPPDQVPNYYTLGNASAQYQAQKPFTVDPPADPGPNPGGGGGQPIPATGTRRTLRQGDSGEDVRYLQQKLSEHGAWLTIDGKFGPATSSAVRSFQASNGLSVDGVVGPQTWAALEGTGGGSTGGSTGGGTSGGWTDPTPQASTRPTLRRGSKGSDVVYLQQRLSAQGYWLTADGSFGPATESAVRSFQRSNGLSADGVVGPMTWAALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEH5</accession>
    <name>A0A1Q2CEH5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3-dehydroquinate synthase</fullName>
            <shortName evidence="8">DHQS</shortName>
            <ecNumber evidence="8">4.2.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">aroB</name>
        <name evidence="10" type="ORF">RPIT_06205</name>
        <name evidence="11" type="ORF">SAMN05428934_103186</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21968"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="EC" id="4.2.3.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="8">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.4" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY69877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06205"/>
    <dbReference type="EnsemblBacteria" id="AQP44455">
        <property type="protein sequence ID" value="AQP44455"/>
        <property type="gene ID" value="RPIT_06205"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY69877">
        <property type="protein sequence ID" value="SDY69877"/>
        <property type="gene ID" value="SAMN05428934_103186"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06205"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003856">
        <property type="term" value="F:3-dehydroquinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00110">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016037">
        <property type="entry name" value="DHQ_synth_AroB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030963">
        <property type="entry name" value="DHQ_synth_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030960">
        <property type="entry name" value="DHQS/DOIS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01761">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001455">
        <property type="entry name" value="DHQ_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01357">
        <property type="entry name" value="aroB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0170">Cobalt</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0520">NAD</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DHQ_synthase" evidence="9">
        <location>
            <begin position="60"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="64"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="122"/>
            <end position="123"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY69877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="355" mass="37357" checksum="9FE381ADEE006E07" modified="2017-04-12" version="1">MSVRVESAQGPYEVHIESGALARLPHLAAGADQVAIIHPASLRALAERTAGLLHRPPTLIEVPDAEAAKTASVLTRCWDALAAAGFTRSDLVVGLGGGTTTDLAGFVAASWLRGVAYVSVPTTVLGMVDAAVGGKTGINLGAGKNLVGAFYEPVAVLCDLDLLASLPARDARAGLAEVIKCGFIADPRILELAGESLSESVDSTTLRFAELVERAVRVKAEVVAADFREATSTGAKVGREALNYGHTLGHAIEAHAGYTWRHGDAIAVGMAWIARVSRDLLGLDRDTVELHDELLGGLGLPLRYDARFEELRPIMSLDKKARGNALRLVGLAGIGRPVILDAPDERTLALVYDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEM3</accession>
    <name>A0A1Q2CEM3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpmE</name>
        <name evidence="8" type="ORF">RPIT_06730</name>
        <name evidence="9" type="ORF">SAMN05428934_110101</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Binds the 23S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ10041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06730"/>
    <dbReference type="EnsemblBacteria" id="AQP44547">
        <property type="protein sequence ID" value="AQP44547"/>
        <property type="gene ID" value="RPIT_06730"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ10041">
        <property type="protein sequence ID" value="SDZ10041"/>
        <property type="gene ID" value="SAMN05428934_110101"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06730"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00501">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002150">
        <property type="entry name" value="Ribosomal_L31"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_L31_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042105">
        <property type="entry name" value="Ribosomal_L31_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33280">
        <property type="entry name" value="PTHR33280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01197">
        <property type="entry name" value="Ribosomal_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01249">
        <property type="entry name" value="RIBOSOMALL31"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01143">
        <property type="entry name" value="RIBOSOMAL_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
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        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
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        </ligand>
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        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
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        </ligand>
    </feature>
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        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ10041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="68" mass="7654" checksum="51815E245CCE4C49" modified="2017-04-12" version="1">MKQGIHPDYVETNVHCTCGNKFTTRSTSKKGDLSADVCAECHPFYTGKQKILDTGGRVARFEKRYAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEM4</accession>
    <name>A0A1Q2CEM4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mycothiol system anti-sigma-R factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06795</name>
        <name evidence="3" type="ORF">SAMN05428934_11087</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44556">
        <property type="protein sequence ID" value="AQP44556"/>
        <property type="gene ID" value="RPIT_06795"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09818">
        <property type="protein sequence ID" value="SDZ09818"/>
        <property type="gene ID" value="SAMN05428934_11087"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06795"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027383">
        <property type="entry name" value="Znf_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13490">
        <property type="entry name" value="zf-HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-HC2" evidence="1">
        <location>
            <begin position="12"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ09818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="84" mass="9747" checksum="390AE86FCE418B5F" modified="2017-04-12" version="1">MSSHEHDEMDECVQALARVHAFLRNELLEVDADLIRHHLHACERCMENFEIESTITEMIQRSQPTPAAPTTLTARIQTLRITHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CER8</accession>
    <name>A0A1Q2CER8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thiamine-monophosphate kinase</fullName>
            <shortName evidence="2">TMP kinase</shortName>
            <shortName evidence="2">Thiamine-phosphate kinase</shortName>
            <ecNumber evidence="2">2.7.4.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">thiL</name>
        <name evidence="5" type="ORF">RPIT_07125</name>
        <name evidence="6" type="ORF">SAMN05428934_11019</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + thiamine phosphate = ADP + thiamine diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15913"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine diphosphate from thiamine phosphate: step 1/1.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thiamine-monophosphate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.16" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07125"/>
    <dbReference type="EnsemblBacteria" id="AQP44614">
        <property type="protein sequence ID" value="AQP44614"/>
        <property type="gene ID" value="RPIT_07125"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08373">
        <property type="protein sequence ID" value="SDZ08373"/>
        <property type="gene ID" value="SAMN05428934_11019"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07125"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00142"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009030">
        <property type="term" value="F:thiamine-phosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02194">
        <property type="entry name" value="ThiL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02128">
        <property type="entry name" value="TMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006283">
        <property type="entry name" value="ThiL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30270">
        <property type="entry name" value="PTHR30270"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005303">
        <property type="entry name" value="Thiam_monoph_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01379">
        <property type="entry name" value="thiL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AIRS" evidence="3">
        <location>
            <begin position="27"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="4">
        <location>
            <begin position="149"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="119"/>
            <end position="120"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDZ08373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="307" mass="31260" checksum="7C641E42162A845F" modified="2017-04-12" version="1">MSSEFELIDTITAGVVVGDDVVVPVGDDAAVLSLAGHTVVTTDMLIENVHFKRQWSSARSIGRKAIAVNVSDLEAMGARPSSVVIALAFPKDLDQQWVVDFEAGAKEECVAAGVSLVGGDLSSSAHVAICVTAIGDMEGTAPVTRAGARPGDVVAVCGKLGWASAGLVVLQRGFGSPKDVVAEQLTPSVPYGQGIAAARAGATAMLDVSDGLLGDLAHIAESSQVLIDVDTALIEIPEQVQRVAAATGKPPLGFVLAGGEDHALAATFPPGAPLPVGWRRVGTVAEGSGVTVDGQPWDGSLGWDHFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CET6</accession>
    <name>A0A1Q2CET6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">Protein RecA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7 8">Recombinase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">recA</name>
        <name evidence="12" type="ORF">RPIT_07085</name>
        <name evidence="13" type="ORF">SAMN05428934_11027</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 9">Belongs to the RecA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07085"/>
    <dbReference type="EnsemblBacteria" id="AQP44607">
        <property type="protein sequence ID" value="AQP44607"/>
        <property type="gene ID" value="RPIT_07085"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08542">
        <property type="protein sequence ID" value="SDZ08542"/>
        <property type="gene ID" value="SAMN05428934_11027"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07085"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00983">
        <property type="entry name" value="recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00268">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013765">
        <property type="entry name" value="DNA_recomb/repair_RecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020584">
        <property type="entry name" value="DNA_recomb/repair_RecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023400">
        <property type="entry name" value="RecA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45900">
        <property type="entry name" value="PTHR45900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00154">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00142">
        <property type="entry name" value="RECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54752">
        <property type="entry name" value="SSF54752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02012">
        <property type="entry name" value="tigrfam_recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00321">
        <property type="entry name" value="RECA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 7 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 7 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="RECA_2" evidence="10">
        <location>
            <begin position="36"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="RECA_3" evidence="11">
        <location>
            <begin position="200"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="66"/>
            <end position="73"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP44607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDZ08542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="347" mass="37197" checksum="B417B557AEFE6700" modified="2017-04-12" version="1">MAVADRTKALEAALAQIEKAHGKGSIMRLGEDNRQPIDVIPTGSVALDVALGIGGLPRGRVIEIYGPESSGKTTVALHAIASAQRDGGICAFIDAEHALDPDYAQKLGVNTDELLVSQPDNGEQALEIADTLVRSGAMALIVIDSVAALTPRAEIEGEMGDSHVGLQARLMSQALRKMTGALKSSNTTAIFINQLREKIGVMFGNPETTTGGRALKFYSSVRLDVRRIETLKDGTEMVGNRTRVKVVKNKVAPPFKQAEFDIIYGQGISREGSLIDLGVDAGIIRKAGAWFTYESDQLGQGKENARTFLKNNPDVAAEIERRIRVHLGVDQEAVPEGIDPVTGEVDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEU5</accession>
    <name>A0A1Q2CEU5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_06990</name>
        <name evidence="9" type="ORF">SAMN05428934_11047</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the auxin efflux carrier (TC 2.A.69) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06990"/>
    <dbReference type="EnsemblBacteria" id="AQP44590">
        <property type="protein sequence ID" value="AQP44590"/>
        <property type="gene ID" value="RPIT_06990"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09002">
        <property type="protein sequence ID" value="SDZ09002"/>
        <property type="gene ID" value="SAMN05428934_11047"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06990"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004776">
        <property type="entry name" value="Mem_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03547">
        <property type="entry name" value="Mem_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ09002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="301" mass="31066" checksum="A8022C117AE3311D" modified="2017-04-12" version="1">MWAVVEGFSTIAAVVAVGYLLARAGITGRPGQRALGDIAFYVAQPALVLRAVSEAELGVLFGWHVVAFGLACIVTGLSFAAIRRRQGATRAEATIGYLATSYVNAANLGLPIAAFVLGDAAWAAPAMLLQVLVLQPSAIASLEASTAGPRRSVLRTFVTHPMVLGGVLGLALNLSGWQPPSLVWGPLALIADLAIPAMLLAFGLSLHSNPLPRLHRMPRSTQAAIATKAVVVPAVALATGLALGLTSDQLRAAVVLAALPTAQVVFVHALRYRVGLGMVQATTVWSTLLSVPVILAAGTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEW4</accession>
    <name>A0A1Q2CEW4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted nucleic acid-binding protein, contains PIN domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07355</name>
        <name evidence="2" type="ORF">SAMN05428934_11428</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000014">
        <property type="protein sequence ID" value="SDZ18302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44648">
        <property type="protein sequence ID" value="AQP44648"/>
        <property type="gene ID" value="RPIT_07355"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ18302">
        <property type="protein sequence ID" value="SDZ18302"/>
        <property type="gene ID" value="SAMN05428934_11428"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07355"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09873">
        <property type="entry name" value="PIN_Pae0151-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044153">
        <property type="entry name" value="PIN_Pae0151-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ18302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="137" mass="15235" checksum="29AC6D5103791DE1" modified="2017-04-12" version="1">MARFVVDAKTLLHVLESGRSVAAEHQLVAPASIRSQVMDLLLARVDAGDLTEKRALALHERLTETKLRLLNDRVSRRTAWDIARQHGRLTIRDAEYIALARLQADALVTIDADLADVATKSVPVAELDYLFQQSPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF17</accession>
    <name>A0A1Q2CF17_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44670">
        <property type="protein sequence ID" value="AQP44670"/>
        <property type="gene ID" value="RPIT_07490"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07490"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="151" mass="15662" checksum="A7B9ACD444D250DB" modified="2017-04-12" version="1">MVRPASAMMNASRASVFALPAYPAWPADSARAAIQLGGADVVAEWLPGLARSTNQGPPGQAHMVEEAVPLVDGGSRKAPPGWPYINDWACSSAGAWCELVIESVFGVRMHPDGGVTAEPVLEHFDPDARLVGLRVAGVTYDVAAGGVSVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF32</accession>
    <name>A0A1Q2CF32_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07755</name>
        <name evidence="2" type="ORF">SAMN05428934_11816</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP44713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44713">
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        <property type="gene ID" value="RPIT_07755"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ21507"/>
        <property type="gene ID" value="SAMN05428934_11816"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
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            <dbReference type="EMBL" id="AQP44713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ21507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="142" mass="15774" checksum="4CB9B81C79078568" modified="2017-04-12" version="1">MVHHEDGSVLTPGRWPWPKDTLAFGWLDPRHPFREGPCPSEVRRGLEEAARSPIDRTRGFHTCAFCPRPAPEEVGPWSPDFHPTEYAAQRGDTLHLGSASIEVMAGGRRWVAPNLVLHYVSEHGYLPPAEVVAALGEPGRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF72</accession>
    <name>A0A1Q2CF72_9ACTN</name>
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        <submittedName>
            <fullName evidence="3">Diacylglycerol kinase</fullName>
        </submittedName>
        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07995</name>
        <name evidence="3" type="ORF">SAMN05428934_11339</name>
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    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07995"/>
    <dbReference type="EnsemblBacteria" id="AQP44753">
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        <property type="gene ID" value="RPIT_07995"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16743">
        <property type="protein sequence ID" value="SDZ16743"/>
        <property type="gene ID" value="SAMN05428934_11339"/>
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        <property type="component" value="Chromosome"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="P:phospholipid biosynthetic process"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATP-NAD_kinase_N"/>
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        <property type="entry name" value="Diacylglycerol/lipid_kinase"/>
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        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
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    </dbReference>
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        <property type="entry name" value="YegS/DAGK_C"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="139"/>
        </location>
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    <evidence type="ECO:0000259" key="1">
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            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDZ16743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="304" mass="32014" checksum="1212FEFF5F627280" modified="2017-04-12" version="1">MTYNVAKRRLVTVVCNEQSGGGRAGRVLGKVARRLREGLPASQLHVVTSDSFEQARDLTRTAALEATAGDIVVVMGGDGMAHLGLNACANTDATLGIIPAGTGNDFARGVGVPSSIKEAVEALVQGRTRVVDLSHVSNGAGERYVGAVVSSGYDARVNRATNDIKLRFGPLSYGYIALRELANFSPIHYRLTIDGEPRELDAMLVAVCNTGVFGGGMQISPDADPSDGLLDVTIIHEASRGKLMRLLPLTYTGSFVKDSAVERFRAARVEVDGDGLFAMGDGEEIGDVPVTVECAPSALRVIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFB5</accession>
    <name>A0A1Q2CFB5_9ACTN</name>
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ19156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44806">
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        <property type="gene ID" value="RPIT_08340"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ19156"/>
        <property type="gene ID" value="SAMN05428934_1157"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SO1590-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11528">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ19156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="124" mass="12972" checksum="A586DDFE550EECC4" modified="2017-04-12" version="1">MVTNATFVIEITPSEGLLPTTGRFDFTKVWSGGAEGTSKGVMLSSGNAAKGTAGFVAMEVFEGRIGSLSGSVSLQQFGTMVGGEQRLTYEVVPGSGTDDFIGITGELHLTIDEDGLHHVRFDIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFJ0</accession>
    <name>A0A1Q2CFJ0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal-binding protein</fullName>
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    <gene>
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    <organism evidence="2 3">
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        <lineage>
            <taxon>Bacteria</taxon>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="YceD"/>
    </dbReference>
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    </dbReference>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="182" mass="20397" checksum="D71C4F093C942675" modified="2017-04-12" version="1">MSPVHHQPDRRSPLVFEMHELARQAGTMKQVTTTVPAPADLGNEVIGVPQDSDIELDLRFEAVTEGVLVTGTATVQLRGQCARCLDDIEDEESFDVQELYFYPGREIEDDEAQIVEEMIDLDEALRDAVVLELPFTPLCEEDCLGLCPQCGFNRNDDPDHTHEQQIDPRWSKLSGLTGDTQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFJ1</accession>
    <name>A0A1Q2CFJ1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FecR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_08895</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44892">
        <property type="protein sequence ID" value="AQP44892"/>
        <property type="gene ID" value="RPIT_08895"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08895"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006860">
        <property type="entry name" value="FecR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04773">
        <property type="entry name" value="FecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FecR" evidence="2">
        <location>
            <begin position="83"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="377" mass="37303" checksum="F802595AB36DD8EA" modified="2017-04-12" version="1">MTACGGTETEAPTPESGVSSTAAVEAEPSPSEEPATEPAPEPSPTPPAAFAVLATAGTSTLDGAPGAAGAELMAGSVVEVTAGPVALQYPDGSVVRLDAGSTFTLGEGETRGTLSEGLSWVRVAPQSAGQFALSVGSAVVTAQGTAFAAGCSGGGCHLAVLEGAVDVDGATVAAGQALALTAGGQPTPAGYDTTFAHEFLKAAADADATEIEGAPDALTLAENLGPKFASWVGTMSGTRTVTACTGTDCGSFPVGDVADRTYTFGVDCTTGFPCVGVGTTTYGMGTETLTAELPMSYDGQQVSYSYQSTYPPCSDDTGQYDTTITWTWTADEAAVVDDAYVVTKATGEAKSINASSDPGSCGATGGTNDGALEVARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFL8</accession>
    <name>A0A1Q2CFL8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_08860</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08860"/>
    <dbReference type="EnsemblBacteria" id="AQP44887">
        <property type="protein sequence ID" value="AQP44887"/>
        <property type="gene ID" value="RPIT_08860"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08860"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="88"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="279"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="91"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="311" mass="34188" checksum="95DFF9B6877DC5AC" modified="2017-04-12" version="1">MTTTTQTPQRPPVAAAMPRKKAPRGIGGASITAFYWMVVPAVAAFAFFHTLPVLVGMFFSFTNYAGYGDWRFVGLSNYINLFRDDRAIGAYLFSFGFAIVATILTNVIALLIAMGLNAKIVGRNFFRGVFFIPYVLAILIVGYIFQYMFSNSLPKILVGIPVFRDNILTNPDWAWTAIVVLAVWQACAFAIIIYLAGLQTIPQELYEAASLDGASAMRQFRSITFPLIGAFFTINMVLSLKGFLQVFDHIVALTNGGPGTATESVTLLIFKGGFAGGEFAYQTANAVIFFIVITVVSLVQFRFLQSREADF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFP7</accession>
    <name>A0A1Q2CFP7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thiol reductase thioredoxin</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Thioredoxin 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09210</name>
        <name evidence="3" type="ORF">SAMN05428934_107154</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY99345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44941">
        <property type="protein sequence ID" value="AQP44941"/>
        <property type="gene ID" value="RPIT_09210"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY99345">
        <property type="protein sequence ID" value="SDY99345"/>
        <property type="gene ID" value="SAMN05428934_107154"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09210"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY99345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="109" mass="11672" checksum="7A2729DDBF461BEE" modified="2017-04-12" version="1">MSLGYEDEQPTRDAVDAMSGEVALEFGANWCGYCRAAKPHLDAALDRRPGVRRVKVADGKGLPLGRSFGVKLWPTLVLLRDGQEVGRVVRPTDRSDVTAALDAAGFSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFT4</accession>
    <name>A0A1Q2CFT4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09420</name>
        <name evidence="4" type="ORF">SAMN05428934_102423</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY60356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09420"/>
    <dbReference type="EnsemblBacteria" id="AQP44976">
        <property type="protein sequence ID" value="AQP44976"/>
        <property type="gene ID" value="RPIT_09420"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY60356">
        <property type="protein sequence ID" value="SDY60356"/>
        <property type="gene ID" value="SAMN05428934_102423"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09420"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544471" evidence="2">
        <location>
            <begin position="33"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="726"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="739"/>
            <end position="753"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY60356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="764" mass="80753" checksum="C30D535F0A88CFCF" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFT5</accession>
    <name>A0A1Q2CFT5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-(apurinic or apyrimidinic site) lyase</fullName>
            <ecNumber evidence="2">4.2.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">RPIT_08965</name>
        <name evidence="17" type="ORF">SAMN05428934_107106</name>
    </gene>
    <organism evidence="16 18">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 18" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1T</strain>
        </source>
    </reference>
    <reference evidence="17 19" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">RP1</strain>
        </source>
    </reference>
    <reference evidence="16" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FPG family.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08965"/>
    <dbReference type="EnsemblBacteria" id="AQP44905">
        <property type="protein sequence ID" value="AQP44905"/>
        <property type="gene ID" value="RPIT_08965"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98369">
        <property type="protein sequence ID" value="SDY98369"/>
        <property type="gene ID" value="SAMN05428934_107106"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08965"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019104">
        <property type="term" value="F:DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08971">
        <property type="entry name" value="AcNei2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015886">
        <property type="entry name" value="DNA_glyclase/AP_lyase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012319">
        <property type="entry name" value="FPG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035937">
        <property type="entry name" value="MutM-like_N-ter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044090">
        <property type="entry name" value="Nei2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000214">
        <property type="entry name" value="Znf_DNA_glyclase/AP_lyase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01149">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06831">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00898">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01232">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81624">
        <property type="entry name" value="SSF81624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51068">
        <property type="entry name" value="FPG_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51066">
        <property type="entry name" value="ZF_FPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="16" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="16" id="KW-0540">Nuclease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FPG_CAT" evidence="15">
        <location>
            <begin position="17"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="FPG-type" evidence="14">
        <location>
            <begin position="222"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="AQP44905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="SDY98369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="266" mass="29435" checksum="9B39289AD24C1194" modified="2017-04-12" version="1">MPEGDTIWRLARRQASLVGRTIEHCELRVPRYATVDLAGTTITRVWAVGKHLLWQCEDLVLQTHLRMDGTWRVHPVGSRWTLPAHTARVVVRVSGGIELVGHDLGVVEVWPVGEMEAHIGYLGPDLLAADWATGGRDEAVQRVAADPHRTIGEALLDQRNLAGIGNEYRAEVCFLRGVHPATPVGRTDAAAAVDLAAKLMRDNLQRPARTFTGDSRPGHHTYVFGRKGRPCRRCSTTIRSGELGAEGQERIIWWCPVCQPTAIDEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFW2</accession>
    <name>A0A1Q2CFW2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent Clp protease adapter protein ClpS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">clpS</name>
        <name evidence="3" type="ORF">RPIT_09515</name>
        <name evidence="4" type="ORF">SAMN05428934_102403</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Binds to the N-terminal domain of the chaperone ClpA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ClpS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY59842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09515"/>
    <dbReference type="EnsemblBacteria" id="AQP44993">
        <property type="protein sequence ID" value="AQP44993"/>
        <property type="gene ID" value="RPIT_09515"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59842">
        <property type="protein sequence ID" value="SDY59842"/>
        <property type="gene ID" value="SAMN05428934_102403"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09515"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00302">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022935">
        <property type="entry name" value="ClpS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003769">
        <property type="entry name" value="ClpS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33473">
        <property type="entry name" value="PTHR33473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02617">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ClpS" evidence="2">
        <location>
            <begin position="21"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY59842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="95" mass="10851" checksum="0ED06D351F3CE34F" modified="2017-04-12" version="1">MSSATEGGLEVLEAPTEESVSPWVTIVWDDPVNLMSYVTYVFQEYFKYPREKAERLMLQVHNDGRAVVSSGNREAMERDVLAMQGYNLWATMEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFW9</accession>
    <name>A0A1Q2CFW9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0434 protein RPIT_09570</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09570</name>
        <name evidence="3" type="ORF">SAMN05428934_102392</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0434 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY59550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09570"/>
    <dbReference type="EnsemblBacteria" id="AQP45004">
        <property type="protein sequence ID" value="AQP45004"/>
        <property type="gene ID" value="RPIT_09570"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59550">
        <property type="protein sequence ID" value="SDY59550"/>
        <property type="gene ID" value="SAMN05428934_102392"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09570"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01187">
        <property type="entry name" value="UPF0434"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005651">
        <property type="entry name" value="Trm112-like"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY59550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="62" mass="6773" checksum="34EA8D0E2E55BB06" modified="2017-04-12" version="1">MDDTMQLTPEFLAIAACPACHAKFAVDYDAKELVCTNEACGLAYPVRDNIPVLLIDQARSTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFX6</accession>
    <name>A0A1Q2CFX6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09645</name>
        <name evidence="4" type="ORF">SAMN05428934_102376</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY59117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09645"/>
    <dbReference type="EnsemblBacteria" id="AQP45018">
        <property type="protein sequence ID" value="AQP45018"/>
        <property type="gene ID" value="RPIT_09645"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59117">
        <property type="protein sequence ID" value="SDY59117"/>
        <property type="gene ID" value="SAMN05428934_102376"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09645"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="DUF304"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="2">
        <location>
            <begin position="77"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY59117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="165" mass="17943" checksum="B273E7812C1E7655" modified="2017-04-12" version="1">MPVNKDQLGNGEQVILTVRTHAKALVGPALLLIVLGSALGIAIALAPPAWQPIATYVAIGVFALLVVWLVLVPFLRWRTSTYTVTDRRIITRKGILNKVGHDLPLRRINNVNYEKSLTDRMLGCGTLVLETAAGQPLMLPDVPGVEKVHRTIADLLFAGDDGYDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFY7</accession>
    <name>A0A1Q2CFY7_9ACTN</name>
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        <submittedName>
            <fullName evidence="4">Predicted membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09720</name>
        <name evidence="4" type="ORF">SAMN05428934_102361</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="STRING" id="1610493.RPIT_09720"/>
    <dbReference type="EnsemblBacteria" id="AQP45029">
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        <property type="gene ID" value="RPIT_09720"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY58706">
        <property type="protein sequence ID" value="SDY58706"/>
        <property type="gene ID" value="SAMN05428934_102361"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
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    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="DUF2207_membrane"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544472" evidence="2">
        <location>
            <begin position="28"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="266"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="448"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY58706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="604" mass="64681" checksum="C0B2BA43B4DFCA1B" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFZ4</accession>
    <name>A0A1Q2CFZ4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphotransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Phosphotransferase enzyme family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09795</name>
        <name evidence="3" type="ORF">SAMN05428934_102347</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY58285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09795"/>
    <dbReference type="EnsemblBacteria" id="AQP45042">
        <property type="protein sequence ID" value="AQP45042"/>
        <property type="gene ID" value="RPIT_09795"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY58285"/>
        <property type="gene ID" value="SAMN05428934_102347"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016740">
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="150"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY58285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="403" mass="44091" checksum="2A5B84255726D203" modified="2017-04-12" version="1">MPDDGMGLLTGDRVEPLLRAVVEHAGGELLSWSLDHVDAAPELSTTATYVATVRWPHGERTELLGVSARTGELTPSDSRAEIFEDGQRRVAVWLYPNDPDLLGLPTAAFPDRMAAALNAGGVFPSPVTPDRLSLTMIGYRPRRRAVVKVVVSDPAETFYVKVLRERLYPDVLAKHRMLREAGVPAPEVALGTDDHLLILRELPGASLAKALFEPGDPCSAEDLIDLLDSMPSSVSQLERRAPWSDAVAHYAAMVTATLPELGDELSWLTERISAGLRGFPPGDEPTHGDFHEGQLRVAGGRVVGVLDVDTIGPGRRADDLACLIGHLSTIQRMNPDQEAKVRDLLRRWVPVFDRRVDPVELRLRAAAVVISLATGPYRSQEVDWRQQTVQMVRSASALVRQVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG21</accession>
    <name>A0A1Q2CG21_9ACTN</name>
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        <recommendedName>
            <fullName evidence="4 6 9">Malate dehydrogenase</fullName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mdh</name>
        <name evidence="13" type="ORF">RPIT_09820</name>
        <name evidence="14" type="ORF">SAMN05428934_102342</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible oxidation of malate to oxaloacetate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6 9">
            <text>(S)-malate + NAD(+) = H(+) + NADH + oxaloacetate</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the LDH/MDH superfamily. MDH type 2 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="3 6 9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY58137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09820"/>
    <dbReference type="EnsemblBacteria" id="AQP45047">
        <property type="protein sequence ID" value="AQP45047"/>
        <property type="gene ID" value="RPIT_09820"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY58137">
        <property type="protein sequence ID" value="SDY58137"/>
        <property type="gene ID" value="SAMN05428934_102342"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09820"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Malate_dehydrog_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
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        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
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        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
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        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
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        <property type="entry name" value="Malate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010945">
        <property type="entry name" value="Malate_DH_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23382">
        <property type="entry name" value="PTHR23382"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="SSF56327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01759">
        <property type="entry name" value="MalateDH-SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00068">
        <property type="entry name" value="MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0520">NAD</keyword>
    <keyword evidence="5 6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Ldh_1_N" evidence="11">
        <location>
            <begin position="7"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Ldh_1_C" evidence="12">
        <location>
            <begin position="157"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6 7">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="13"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
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        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="130"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP45047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY58137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="329" mass="34720" checksum="948DB459D793D629" modified="2017-04-12" version="1">MSTAAPVKIAVTGAAGQICYSLLFRIASGSLLGDTPIELRLLEITPALKALEGVVMELDDCAFGNLVNIEIGDDPNKVFDGVNLAMLVGAMPRKAGMERGDLLSANGAIFTAQGKALNEVAADDVKVLVTGNPANTNALIAQQNAPDIPAERFNALTRLDHNRALSQLAAKLGVSVTEISHMTIWGNHSATQYPDLFNAKVNGQSAAEAVNDQEWIENTFIPTVAKRGAAIIEARGLSSAASAANATVEHMRDWVSGTKEGDWVSMAVPSDGSYGVPEGLISSFPCTVKDGKYEIVQGLDLNEFSRSKIDASVAELVDERNAVTELGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG55</accession>
    <name>A0A1Q2CG55_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10110</name>
        <name evidence="3" type="ORF">SAMN05428934_102283</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY56498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10110"/>
    <dbReference type="EnsemblBacteria" id="AQP45099">
        <property type="protein sequence ID" value="AQP45099"/>
        <property type="gene ID" value="RPIT_10110"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56498">
        <property type="protein sequence ID" value="SDY56498"/>
        <property type="gene ID" value="SAMN05428934_102283"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10110"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="38"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY56498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="217" mass="23826" checksum="30D68D643E718C12" modified="2017-04-12" version="1">MTAELWDSRYSHPNYLFGYRPNDFLKAQARLLRPGSRVLCLGDGEGRNGVWLAERGHSVVSLDFSGVALAKAEALAAERGVSIETRQVDLAQWVDDPDPPRPWDAVVVIFVHLRPELRQRVAQAVTRQSAPGAALILENYTPAQLALGTGGPKQPELLTTREDVLADWQGWHLDVRLVERRIFEGMGHQGLSSVVQALGLRTGPEVDPVASTGHRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG62</accession>
    <name>A0A1Q2CG62_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Adenosine deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_09755</name>
        <name evidence="5" type="ORF">SAMN05428934_102354</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY58492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09755"/>
    <dbReference type="EnsemblBacteria" id="AQP45035">
        <property type="protein sequence ID" value="AQP45035"/>
        <property type="gene ID" value="RPIT_09755"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY58492">
        <property type="protein sequence ID" value="SDY58492"/>
        <property type="gene ID" value="SAMN05428934_102354"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09755"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019239">
        <property type="term" value="F:deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409">
        <property type="entry name" value="PTHR11409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01430">
        <property type="entry name" value="aden_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="A_deaminase" evidence="3">
        <location>
            <begin position="10"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY58492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="353" mass="39341" checksum="8C9031986A4DA110" modified="2017-04-12" version="1">MDIDDIRRLPKVALHDHLDGGLRPQTVIDLCTENGHPLPTTDADELSDWFFEAADSGSLVRYLETFEHTVAAMQTTAQLARVAHEFVVDQALDGVVYAEARYSPQLHRQQGLTLEKVVEAVRDGLMSGMAEASRRGHHITARQIVTSMRHTEPTLDTARLALAYRDDSVCGFDIAGAEDGFPPSRFADAFDFLKRNNMFFTIHAGEAFGLPSIWEAVQVCGADRLGHGVRIVEDITIDEDTARLGRLAAYVRDARIPLEVAPSSNLQTGIAATMSEHPVGLLRDLQFNVTINCDNRLMSRTTMSREFALLVEAFGWDKADIEWCTINAMRAAFLPHDHRESIVREVIRPAYRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG65</accession>
    <name>A0A1Q2CG65_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10180</name>
        <name evidence="3" type="ORF">SAMN05428934_102269</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
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    <sequence length="153" mass="16365" checksum="04DA43C6BA602D13" modified="2017-04-12" version="1">MIWVACGIVAIGVLAAAAFAGLGRFGGMPQDPVLDQFRGRVPDGPVDESLLERLQLPTSSSGYARHEVDDYLRDVAAGTAPPPSEATFSVVRGGYEMATVDNLIERERYERPTAATDDEPPALPATHGADTPPDEGEVPETSRRPDDGWTDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">RP1</strain>
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        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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    <dbReference type="InterPro" id="IPR025841">
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            <end position="496"/>
        </location>
    </feature>
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        <location>
            <begin position="474"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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            <dbReference type="EMBL" id="AQP45117.1"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY55953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
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            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="523" mass="57314" checksum="5D1708807527896E" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGD3</accession>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
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        </source>
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9 11">RP1</strain>
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    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10140"/>
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    </evidence>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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            <dbReference type="EMBL" id="SDY56331.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGD6</accession>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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                <person name="de Groot N.N."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY53953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10550"/>
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        <property type="protein sequence ID" value="AQP45182"/>
        <property type="gene ID" value="RPIT_10550"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY53953"/>
        <property type="gene ID" value="SAMN05428934_102195"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="DUF255"/>
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        <property type="entry name" value="Thioredoxin-like_sf"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="3"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY53953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="669" mass="73031" checksum="65903263E47D0C5E" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGK9</accession>
    <name>A0A1Q2CGK9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-3-methyladenine glycosylase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">DNA-3-methyladenine glycosylase I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10925</name>
        <name evidence="3" type="ORF">SAMN05428934_102118</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY51612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10925"/>
    <dbReference type="EnsemblBacteria" id="AQP45244">
        <property type="protein sequence ID" value="AQP45244"/>
        <property type="gene ID" value="RPIT_10925"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY51612">
        <property type="protein sequence ID" value="SDY51612"/>
        <property type="gene ID" value="SAMN05428934_102118"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10925"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008725">
        <property type="term" value="F:DNA-3-methyladenine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005019">
        <property type="entry name" value="Adenine_glyco"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03352">
        <property type="entry name" value="Adenine_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY51612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="187" mass="20992" checksum="D955560C50510DDC" modified="2017-04-12" version="1">MTRTRCFGTGDELYEAYHDEEWGRPFGDSPDERELFERLCLEGFQAGLSWLTVLRKREAFREVFEGFEPAVVARFEDDDVERLMGDPRIIRNRAKILAAVGNARALLAMHSDGERLGDLIAQHAPPPRERPPANADEVPGSTAETEALSRELKKKGFRFVGPTTLYALMQASGLVDDHVEGCWLAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGS3</accession>
    <name>A0A1Q2CGS3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TetR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_10930</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10930"/>
    <dbReference type="EnsemblBacteria" id="AQP45245">
        <property type="protein sequence ID" value="AQP45245"/>
        <property type="gene ID" value="RPIT_10930"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10930"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045823">
        <property type="entry name" value="TetR_C_32"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19344">
        <property type="entry name" value="TetR_C_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="22"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="228" mass="25245" checksum="1433E39BF7FA13C7" modified="2017-04-12" version="1">MTDVSTRQPARARRSRTRMTAAERREQLIGIARELFAERGFEGTSVEEIAARAGVSKPVVYEHFGGKEGAYAVVVDRETQTLHNAIRAALTTPEAGSRELLERGAMALLDYIDRCPDGFRILSRDSSLGHPTGTFASILNDITVQVEDLLGLQFQRTGHDPALARLYAQALVGLVAQTGQQWLDHRDPPKEVVARHVINLAWNGMAHLQPDPQLVIETIDKRRTEDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGX6</accession>
    <name>A0A1Q2CGX6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_11690</name>
        <name evidence="6" type="ORF">SAMN05428934_106137</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11690"/>
    <dbReference type="EnsemblBacteria" id="AQP45378">
        <property type="protein sequence ID" value="AQP45378"/>
        <property type="gene ID" value="RPIT_11690"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93685">
        <property type="protein sequence ID" value="SDY93685"/>
        <property type="gene ID" value="SAMN05428934_106137"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11690"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001761">
        <property type="entry name" value="Peripla_BP/Lac1_sug-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00532">
        <property type="entry name" value="Peripla_BP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="12"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY93685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="345" mass="37407" checksum="24714F821510D18C" modified="2017-04-12" version="1">MDRPRGSTTKKPTLKNVAELAGVSPMTASRVVAGGDGVSPAMVRRVQAAVKTLGYSRNEAARLMRPGQRSGLLGVIITNIDNPYYAQVLLGIESAAQEAGRLIITGISHNDPRLEAQLVKDLVARQIEGLIVVPASTDAPHLSRAAAAGMPIVLASRSIDQGGVDTVLVDDIDGVRAVLSDKLRQGEHPMAFIGGPDSIATAARRYRGFALAHADAGLDIRPDLVERLPAEREPVMAATRRLLDLDQPPRAFFTTNNRYTVHVLRVLLQERNRWATWEDRPPLVGFDSFELADLVPYPLTLIEHDARAMGRIAGELALRRIDHRDSTPPMTTTLPSVGVVVGQRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGZ5</accession>
    <name>A0A1Q2CGZ5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11665</name>
        <name evidence="3" type="ORF">SAMN05428934_106142</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45373">
        <property type="protein sequence ID" value="AQP45373"/>
        <property type="gene ID" value="RPIT_11665"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93783">
        <property type="protein sequence ID" value="SDY93783"/>
        <property type="gene ID" value="SAMN05428934_106142"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11665"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY93783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="717" mass="78808" checksum="843A3DECCD6480B8" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH17</accession>
    <name>A0A1Q2CH17_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AbiEi antitoxin, Type IV TA system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_11910</name>
        <name evidence="2" type="ORF">SAMN05428934_10693</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45416">
        <property type="protein sequence ID" value="AQP45416"/>
        <property type="gene ID" value="RPIT_11910"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92735">
        <property type="protein sequence ID" value="SDY92735"/>
        <property type="gene ID" value="SAMN05428934_10693"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11910"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025159">
        <property type="entry name" value="AbiEi_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13338">
        <property type="entry name" value="AbiEi_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY92735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="305" mass="33783" checksum="C76C228F477E4763" modified="2017-04-12" version="1">MSIAPLIRHSDLVARGHDPNEIRSLVRSGRLHRVRHGVYSYDRPAGMDAHLQLLRATVPIVDAGNVISHASAGVLHGLPVPAEYLDRVWMTRRSPGHGDHGKQLVVRHTPIHDDEVRLSSYGPVTSLSRTASDLARTLEPRWGLAAVDAALRLGTSEADLYSSLALHPKLRGTRRARHIIRICDARAESPAESISRYHMRTAGLPLPELQYDHFDADGVFVARSDFFWPEYGLVGEVDGAGKYEELLRPGQTPTQAIMAEKRRDEALRSLGLWVIHWDWQTANDEAALTVLLAGALRRQAGRLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH64</accession>
    <name>A0A1Q2CH64_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Deoxyribose-phosphate aldolase</fullName>
            <shortName evidence="3">DERA</shortName>
            <ecNumber evidence="3">4.1.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">2-deoxy-D-ribose 5-phosphate aldolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Phosphodeoxyriboaldolase</fullName>
            <shortName evidence="3">Deoxyriboaldolase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">deoC</name>
        <name evidence="4" type="ORF">RPIT_12170</name>
        <name evidence="5" type="ORF">SAMN05428934_10642</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12821"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:62877"/>
            <dbReference type="EC" id="4.1.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.4" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY91594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12170"/>
    <dbReference type="EnsemblBacteria" id="AQP45466">
        <property type="protein sequence ID" value="AQP45466"/>
        <property type="gene ID" value="RPIT_12170"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY91594">
        <property type="protein sequence ID" value="SDY91594"/>
        <property type="gene ID" value="SAMN05428934_10642"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12170"/>
    <dbReference type="UniPathway" id="UPA00002">
        <property type="reaction ID" value="UER00468"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004139">
        <property type="term" value="F:deoxyribose-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046386">
        <property type="term" value="P:deoxyribose phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00959">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00114">
        <property type="entry name" value="DeoC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011343">
        <property type="entry name" value="DeoC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028581">
        <property type="entry name" value="DeoC_typeI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889">
        <property type="entry name" value="PTHR10889"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889:SF1">
        <property type="entry name" value="PTHR10889:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001357">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00126">
        <property type="entry name" value="deoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with acetaldehyde" evidence="3">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY91594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="229" mass="23257" checksum="9CFE9FD9AE8C3ADE" modified="2017-04-12" version="1">MQITRSALAQMVDHTLLKTDATRAQVSALVAEARELGVFSVCVSPSMLPITDELGDVKVATVCGFPSGNHTAAAKAAEAAESSKLGADEIDMVINIGLLKEGRADAVEEEIRAVREATTGLLKVIIESAALTDDEIVAACKAAEAAGADYVKTSTGFHPAGGASAHAVKLMADTVGGRLGVKASGGIRDFASANEMVEAGATRLGLSGTRAVLDGADGVEIDDEGDGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHC0</accession>
    <name>A0A1Q2CHC0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_12485</name>
        <name evidence="4" type="ORF">SAMN05428934_104189</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY80270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12485"/>
    <dbReference type="EnsemblBacteria" id="AQP45518">
        <property type="protein sequence ID" value="AQP45518"/>
        <property type="gene ID" value="RPIT_12485"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY80270">
        <property type="protein sequence ID" value="SDY80270"/>
        <property type="gene ID" value="SAMN05428934_104189"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12485"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005182">
        <property type="entry name" value="DUF304"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03703">
        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="346"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="370"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="2">
        <location>
            <begin position="65"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY80270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="483" mass="51507" checksum="389FC739567B0743" modified="2017-04-12" version="1">MTQWFRNSRRAVAAEYLGALPNLALAIVGLVVVETTPGTGLSEVLRVAGWLYLAVLVLEPPVGYWGNRFLMTPAALVHDRGIIHKTVRSIPWDSITGFDVDTPWAHRLLGVHKVTIAQAGGEETRVALRGLDPQLVDALRARLADTARPTIADGERPTDPTPSPAGTIVHRAGKGSLAVMSVAHGQIVVVGLALLLSAWELADQLGLTGAVGPLVSDLPLVTRVAVGLVVGLSGGLLITLARYHDFRVESLPDGQLLTSYGWFARRERRFDADAVQGLIVHRNIVELLLGRARLGVLTRDSGARLASNTVIPSAPLATVERVAGEHFGHLSPAPSRVRDDHRAARALGWAVGLVSPAVGLGLAAEWVGLPLWSALLIAASAWLLLSVAAKAAVTQFAWDPSRRAIHVTTQFTHVRETTLRASAVHGLGSTAWRSAPHRLWAAWLGVYAGGPRRYVSLRTPFADLAAVASAIATHRSPLTESTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHD3</accession>
    <name>A0A1Q2CHD3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1,4-dihydroxy-2-naphthoyl-CoA synthase</fullName>
            <shortName evidence="3">DHNA-CoA synthase</shortName>
            <ecNumber evidence="3">4.1.3.36</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">menB</name>
        <name evidence="4" type="ORF">RPIT_12280</name>
        <name evidence="5" type="ORF">SAMN05428934_10620</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>2-succinylbenzoyl-CoA + H(+) = 1,4-dihydroxy-2-naphthoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:26562"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57364"/>
            <dbReference type="ChEBI" id="CHEBI:58897"/>
            <dbReference type="EC" id="4.1.3.36"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 6/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.36" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY91102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12280"/>
    <dbReference type="EnsemblBacteria" id="AQP45483">
        <property type="protein sequence ID" value="AQP45483"/>
        <property type="gene ID" value="RPIT_12280"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY91102">
        <property type="protein sequence ID" value="SDY91102"/>
        <property type="gene ID" value="SAMN05428934_10620"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12280"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00167"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008935">
        <property type="term" value="F:1,4-dihydroxy-2-naphthoyl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01934">
        <property type="entry name" value="MenB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010198">
        <property type="entry name" value="DHNA-CoA_synthase_MenB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43113">
        <property type="entry name" value="PTHR43113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01929">
        <property type="entry name" value="menB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="87"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="141"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="3">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="3">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="3">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY91102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="298" mass="33186" checksum="95BC68586BBF5114" modified="2017-04-12" version="1">MTNPFRAELWEPVAGFEFTDITYHRAKHVPAVRIAFDRPEVRNAFRPHTVDELYQALEHARTSSDIGCVLLTGNGPSEKDGGWAFCSGGDQRIRGRAGYQYAEGETSESVDAAKLGRLHILEVQRLIRFMPKVVIALVNGWAAGGGHSLHVVADLTLASREHAKFKQTDADVGSFDAGYGSAYLARQVGQKFAREIFFLGDVHDAEDAHRMGMVNRVIPHAELEDVGLEWAAKICGKSPTAQRMLKYAFNAIDDGLVGQQVFAGETTRLAYMTDEAVEGRDAFLEKRDPDWSRFPYYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHE2</accession>
    <name>A0A1Q2CHE2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SH3b domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_12345</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12345"/>
    <dbReference type="EnsemblBacteria" id="AQP45493">
        <property type="protein sequence ID" value="AQP45493"/>
        <property type="gene ID" value="RPIT_12345"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12345"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003646">
        <property type="entry name" value="SH3-like_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08239">
        <property type="entry name" value="SH3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00287">
        <property type="entry name" value="SH3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51781">
        <property type="entry name" value="SH3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013247441" description="SH3b domain-containing protein" evidence="2">
        <location>
            <begin position="31"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="SH3b" evidence="3">
        <location>
            <begin position="145"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="358" mass="36424" checksum="C19EDBECEFB567CE" modified="2017-04-12" version="1">MARLVMAPIAILSVVGLAAGLMVVPRPEVAAVTEPAKATVTLPLGISRSQSRPSLSTPTPSPSASPSPTTSPSPSTSPSPAPSPSVNAGPLPGLPIAPTPAPTPTPTVTAPAPAPSTPPAEKPAAVKAEKPAAPKVDYAKLGAEAGTRYSTASVNVRTGPGTGFDVRTSIAEGKAVTITDREVDGWRQVVISKRSGWIKGSFLTKTAPPKPSPKPAPKATATATKTQSSSGGGESSSSTSTAACAKASGIESGLTSRTRTVLRAVCAAFPKVSSYGGRRSGGGSYHSSGQAIDVMVSGDYGWQIARWARANAGSLGIIEVIYSQKIWTSQRSGDGWRSMSDRGSASANHYDHVHISVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHF5</accession>
    <name>A0A1Q2CHF5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">dTDP-4-dehydrorhamnose reductase</fullName>
            <ecNumber evidence="6">1.1.1.133</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_12650</name>
        <name evidence="9" type="ORF">SAMN05428934_104156</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dTDP-beta-L-rhamnose + NADP(+) = dTDP-4-dehydro-beta-L-rhamnose + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21796"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57510"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="1.1.1.133"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the dTDP-4-dehydrorhamnose reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.133" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY79342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12650"/>
    <dbReference type="EnsemblBacteria" id="AQP45549">
        <property type="protein sequence ID" value="AQP45549"/>
        <property type="gene ID" value="RPIT_12650"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY79342">
        <property type="protein sequence ID" value="SDY79342"/>
        <property type="gene ID" value="SAMN05428934_104156"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12650"/>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008830">
        <property type="term" value="F:dTDP-4-dehydrorhamnose 3,5-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008831">
        <property type="term" value="F:dTDP-4-dehydrorhamnose reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000888">
        <property type="entry name" value="dTDP_sugar_isom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="PTHR10491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00908">
        <property type="entry name" value="dTDP_sugar_isom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD_sub_bind" evidence="7">
        <location>
            <begin position="187"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <feature type="site" description="Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose" evidence="5">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600888-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600888-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY79342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="459" mass="49199" checksum="1616769634595F96" modified="2017-04-12" version="1">MTNELRVSTTDIPGLLVVDLPVHGDSRGWFKENWQRDKMTALGVPDFQPVQNNMSFNADAGVTRGIHAEPWDKLVSVATGRVFGAWVDLRAGETFGTVVTAELTPGRAVFVPRGVGNAYQALDPGTCYSYLVNEHWSADAKAKYTFANLRHPDIRWPLPLDGATISEADRSHPSIADVVPFRRPRPVVTGSNGQLGTALQALIPEAIFVDRADLDITDADAVAAFDWSEASCIINAAAWTAVDAAEGEGRAACWAVNVAGTANLVAAARRHRLPLVHISSDYVFDGSRELHTEDEPFAPLSAYGAAKAAADAVVGTLPRHYILRTSWVIGEGSNFVRTMARLADTGASPAVVDDQFGRLTFADDLARAALHLMHHAEPGTYNVTSDGGVVSWFDVAQAVFEARGAAGQVSRTSTEEFAAGKLTAPRPRHSALDLTKLRATGFVPVDGGEGLRQYLAAMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHG5</accession>
    <name>A0A1Q2CHG5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cellobiose ABC transporter membrane protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_12750</name>
        <name evidence="7" type="ORF">SAMN05428934_104137</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY78784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12750"/>
    <dbReference type="EnsemblBacteria" id="AQP45566">
        <property type="protein sequence ID" value="AQP45566"/>
        <property type="gene ID" value="RPIT_12750"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY78784">
        <property type="protein sequence ID" value="SDY78784"/>
        <property type="gene ID" value="SAMN05428934_104137"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12750"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="221"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="98"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY78784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="302" mass="32813" checksum="6114DC5BE7891518" modified="2017-04-12" version="1">MSSQMSSPMAQQLAGKGAAKAIRRRLHGVDKRPGWRTYLALAVVLIISIYPIYFTVLLASSNAADIARNPIPSMLPAGELMDNISRVVRSDIQFWTALRNSIIVSTITAVSVVFFSTLAGYSFAKLRFRGSNGLLVFVIATMAVPTQLSIVPMFILMSELDWVGKLQAVIVPGMVTAFGVFWMTQYLREALPFELIEAARVDGASMIRTFWSIALPAARPAAAMLGLFTFVGAWTNFFWPFIILGSANPTLPVALQLLQASYFKDYSLIMAGVVVATLPLVLLFVVAGRQLVAGIMQGAVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHM6</accession>
    <name>A0A1Q2CHM6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative hydrolase of the HAD superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_13005</name>
        <name evidence="2" type="ORF">SAMN05428934_10486</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13005"/>
    <dbReference type="EnsemblBacteria" id="AQP45611">
        <property type="protein sequence ID" value="AQP45611"/>
        <property type="gene ID" value="RPIT_13005"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY77394">
        <property type="protein sequence ID" value="SDY77394"/>
        <property type="gene ID" value="SAMN05428934_10486"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13005"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY77394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="199" mass="21852" checksum="A6E5BBD2BE216F20" modified="2017-04-12" version="1">MIRAVVFDLGQVLASPPNLYVDAADRLGVSAADYEANYWADRPAYDDGASDAEYWGPLLRTLGLTPTDDDIAEMARLDSELWIQVRPEAHALLRDTRAAGRTVAVLSNAPHAIAAAAEHSAWRADIDRLFISAPMGYSKPEPACFRQVQHELGLDADQIAFIDDRHPNVDGALAVGWHAHLWADDADTRAWLQELGVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHP0</accession>
    <name>A0A1Q2CHP0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alanine racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13090</name>
        <name evidence="4" type="ORF">SAMN05428934_10469</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY76908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13090"/>
    <dbReference type="EnsemblBacteria" id="AQP45627">
        <property type="protein sequence ID" value="AQP45627"/>
        <property type="gene ID" value="RPIT_13090"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY76908">
        <property type="protein sequence ID" value="SDY76908"/>
        <property type="gene ID" value="SAMN05428934_10469"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13090"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006522">
        <property type="term" value="P:alanine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000821">
        <property type="entry name" value="Ala_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00992">
        <property type="entry name" value="ALARACEMASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_N" evidence="2">
        <location>
            <begin position="7"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600821-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY76908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="339" mass="36042" checksum="82A31F78E93D4B5F" modified="2017-04-12" version="1">MPLTLTINTDAWRSHQRSLLADVPGLVPVLKGNGYGFGLDLLAREATALGVGSISVGIAQEVAAVRAGGWTGDVVVLNPWRPFDDAATALLDDPGVIATISRADDLRAVAAEHPTARVIVEIETAMHRHGLDPRNLTAEDFGELTFEGWAVHLPSSGLLVEARRLAATGVSVRPAPVWVSHLSVADYAQFAREFDARMRVGTRLWLGDKAAYHTTATVLDVHPVKRGQELGYHSVKAPKEGHLVIVSGGTAHGVAMAAPTPQRSLRQRGVTAAQGVLDALGRSLSPFTIGGRKRAFAEPPHMHSSMVFVPGATPPAQVGDVVPVTTRMTTVTPDEVRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHY1</accession>
    <name>A0A1Q2CHY1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin reductase</fullName>
            <ecNumber evidence="3">1.8.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_13530</name>
        <name evidence="7" type="ORF">SAMN05428934_11193</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:20345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="4">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.9" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ13262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13530"/>
    <dbReference type="EnsemblBacteria" id="AQP45704">
        <property type="protein sequence ID" value="AQP45704"/>
        <property type="gene ID" value="RPIT_13530"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ13262">
        <property type="protein sequence ID" value="SDZ13262"/>
        <property type="gene ID" value="SAMN05428934_11193"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13530"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019430">
        <property type="term" value="P:removal of superoxide radicals"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008255">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005982">
        <property type="entry name" value="Thioredox_Rdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01292">
        <property type="entry name" value="TRX_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00573">
        <property type="entry name" value="PYRIDINE_REDOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="5">
        <location>
            <begin position="7"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ13262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="313" mass="33227" checksum="43121A10619126C9" modified="2017-04-12" version="1">MSADTIHDVIIVGSGPAGYTAAIYAARANLKPLVFEGAFDSGGALMNTTEVENYPGFPEGIQGPDLMTAMRSQAERFGASLITDDVTALDLTGEIKVVKDSEDVEYRGRSVILAMGSAYRKLGLPDEDRLSGRGVSYCATCDGAFFRDKPIAVVGGGDSAMEEATFLSRFGSKVVVVHRRDELRASKIMAERAMNDPKIEFAWNSAVSGINGANSVESITLTDTVTGETRDVEINGLFVAIGHDPRSDLVKDEVHLDANGYVLVEGRTTATNLPGVFACGDLVDHNYRQAITAAGSGCSAALDAERFLASLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHY4</accession>
    <name>A0A1Q2CHY4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative ABC transport system ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_13625</name>
        <name evidence="7" type="ORF">SAMN05428934_11174</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13625"/>
    <dbReference type="EnsemblBacteria" id="AQP45721">
        <property type="protein sequence ID" value="AQP45721"/>
        <property type="gene ID" value="RPIT_13625"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12945">
        <property type="protein sequence ID" value="SDZ12945"/>
        <property type="gene ID" value="SAMN05428934_11174"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13625"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="5"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="259"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="259"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ12945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="311" mass="33637" checksum="72133E7CDEA62714" modified="2017-04-12" version="1">MSIAARAQGLTKTYGSGSTVVTALDNVDFEVVSGEFTAIMGPSGSGKSTLMHLLAALDTPTSGEIFIGDTAVGRMADTPLTELRRDRIGFIFQAFNLVPTLSARENIVLPISIAGKKVDEQWFDRIVDVLGLRDRLNHKPAELSGGQQQRVACARALMNRPDIVFGDEPTGNLDSTAAGEVLGFLRRSVDDFQQTVVMVTHDAHAASYADRVVFLSDGHIVHELRGATQEELLNAMSVLYPRTDDAATEHVTHSHHLVELGETPEESEAIDAHADALYRDGSPPPPPRDGIDETDVESTAERSLARRALLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHY8</accession>
    <name>A0A1Q2CHY8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyridoxal-5'-phosphate-dependent protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">dTDP-4-amino-4,6-dideoxygalactose transaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_13760</name>
        <name evidence="5" type="ORF">SAMN05428934_11148</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13760"/>
    <dbReference type="EnsemblBacteria" id="AQP45739">
        <property type="protein sequence ID" value="AQP45739"/>
        <property type="gene ID" value="RPIT_13760"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12487">
        <property type="protein sequence ID" value="SDZ12487"/>
        <property type="gene ID" value="SAMN05428934_11148"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13760"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ12487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="383" mass="40779" checksum="0E81C322CAD0FAAA" modified="2017-04-12" version="1">MTGKLFLSSPDVTQLEEDAVVRAVRSGWIAPLGPEVDAFEAELAEYTGRRFAVALSSGTAALHLGLLTLGVGTGDVVVTSSLTFAATANAVVYTGAEPVFVDCDHTGNMNPDLLEEAMTTLAAEGRSVKAVVPVDMIGKVADHARIGEIAARHGAIVLSDAAESMGATRDGRSAAAFGVASALSFNGNKIMTTSGGGALLTDDEAIAKHVRYLATQARQPVVHYEHTDIGYNYRLSNVLAALGRAQLSRLDAMIERRREIRGRYRDLFADVPGVTLFGEPDAPSEGTRDNCWLTAITVDPEISGFTANDLWEALAQGNIESRPLWKPMHAQPVFADARSFTDGTSDELFRTGLTLPSGSVLTDDDLDRVTGAVVSFLEQRRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI08</accession>
    <name>A0A1Q2CI08_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ferrous iron transport protein B</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Ferrous iron transporter B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13730</name>
        <name evidence="4" type="ORF">SAMN05428934_11153</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13730"/>
    <dbReference type="EnsemblBacteria" id="AQP45734">
        <property type="protein sequence ID" value="AQP45734"/>
        <property type="gene ID" value="RPIT_13730"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12579">
        <property type="protein sequence ID" value="SDZ12579"/>
        <property type="gene ID" value="SAMN05428934_11153"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13730"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01879">
        <property type="entry name" value="FeoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011640">
        <property type="entry name" value="Fe2_transport_prot_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030389">
        <property type="entry name" value="G_FEOB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07664">
        <property type="entry name" value="FeoB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02421">
        <property type="entry name" value="FeoB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51711">
        <property type="entry name" value="G_FEOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="332"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="398"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="459"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="586"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="617"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="FeoB-type G" evidence="2">
        <location>
            <begin position="16"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ12579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="642" mass="68186" checksum="7280E601C93D98BC" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI18</accession>
    <name>A0A1Q2CI18_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_trans_2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13860"/>
    <dbReference type="EnsemblBacteria" id="AQP45757">
        <property type="protein sequence ID" value="AQP45757"/>
        <property type="gene ID" value="RPIT_13860"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13860"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="368" mass="41305" checksum="B1DBB0D986C79906" modified="2017-04-12" version="1">MSVIVPVYNTAKYLEQSVGSVLRQSFPDFELLLIDDGSTDESPVMCDAFALRDSRVKVFHQSNSGVSAARNTGLDHARGEFVAFLDSDDWFGEETLASAVSAAELHRVDVVLWPYVREYAGLSLERDFFNFTPGRFSKEDTRELVCRRIAGLLDEELAHPDSADALVTVWGKLYRRQLITSVDARFTDLSVIGTAEDALFNLQVLSRASSAYYLDSHLYHYRRDNVTSLTQSYKPGLPGQWRELHRRMRDFISDHQLGPSFTQALANRISLSIIGLGLNALRSRKGPVRTVQAVRNLLLDDEYRAAVAELDLRWFPISWRVFFGAAKAGNALVVSTMLAGAQAIIDHRSRTPGSRRLGDLFGRQRRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI63</accession>
    <name>A0A1Q2CI63_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SAF domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_14220</name>
        <name evidence="5" type="ORF">SAMN05428934_11226</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ14681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14220"/>
    <dbReference type="EnsemblBacteria" id="AQP45816">
        <property type="protein sequence ID" value="AQP45816"/>
        <property type="gene ID" value="RPIT_14220"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ14681">
        <property type="protein sequence ID" value="SDZ14681"/>
        <property type="gene ID" value="SAMN05428934_11226"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14220"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="SAF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08666">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="SAF" evidence="3">
        <location>
            <begin position="58"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ14681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="212" mass="21985" checksum="AD07E40DC3C52727" modified="2017-04-12" version="1">MLTTQRPTKPDAAPDTPRPAAVQLRARRSPKLIALGVLLVTLGGLAAAFLFSLNSEQRPVLVMERDVRRGAVIAPEDLAVIEVPGGLQLEALTPESRADIIGQQALSDLPRGSFPLTQHVGADPLPEGQSLVGLRLPHGRLPATELFSGTVVSLVSLADGDDSAIAGVLSSPPVALEDGTFSVDVLVADVDAARAAKLGATDLLALMVTEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI67</accession>
    <name>A0A1Q2CI67_9ACTN</name>
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        <submittedName>
            <fullName evidence="2">Adenylate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_13820</name>
        <name evidence="2" type="ORF">SAMN05428934_11136</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
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    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45750">
        <property type="protein sequence ID" value="AQP45750"/>
        <property type="gene ID" value="RPIT_13820"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12252">
        <property type="protein sequence ID" value="SDZ12252"/>
        <property type="gene ID" value="SAMN05428934_11136"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13820"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ12252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="216" mass="23394" checksum="BDA266D5B1AA3A5B" modified="2017-04-12" version="1">MIVEFVGPPGAGKSTIARELARLTGQSSVTLDGYRTPQGRLLSPREVTLQRWWSAASQPALARAALDCARREGRGLALSWMINLARRNRMMEDLEGGGLILEEGTLSALCLAQAARSRPWEMLSVLPHLAHGDTVVVIDIDVDTAVERIRLRQGILADRDAGSLRRLISGYQSALAELSSAIDPAPIQMTSDQLPNIIAARLLELLSEPALARGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI94</accession>
    <name>A0A1Q2CI94_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alkyldihydroxyacetonephosphate synthase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">FAD-binding oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_14395</name>
        <name evidence="4" type="ORF">SAMN05428934_11261</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ15333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14395"/>
    <dbReference type="EnsemblBacteria" id="AQP45849">
        <property type="protein sequence ID" value="AQP45849"/>
        <property type="gene ID" value="RPIT_14395"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ15333">
        <property type="protein sequence ID" value="SDZ15333"/>
        <property type="gene ID" value="SAMN05428934_11261"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14395"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="104"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="550"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ15333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="569" mass="62645" checksum="0B3C47BD44824507" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIE0</accession>
    <name>A0A1Q2CIE0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S9 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14685"/>
    <dbReference type="EnsemblBacteria" id="AQP45898">
        <property type="protein sequence ID" value="AQP45898"/>
        <property type="gene ID" value="RPIT_14685"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14685"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9" evidence="1">
        <location>
            <begin position="343"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="562" mass="61498" checksum="3399FC0D6C4A1D0A" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIE8</accession>
    <name>A0A1Q2CIE8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FMN reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14265</name>
        <name evidence="3" type="ORF">SAMN05428934_11235</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ14857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14265"/>
    <dbReference type="EnsemblBacteria" id="AQP45825">
        <property type="protein sequence ID" value="AQP45825"/>
        <property type="gene ID" value="RPIT_14265"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ14857">
        <property type="protein sequence ID" value="SDZ14857"/>
        <property type="gene ID" value="SAMN05428934_11235"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14265"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023932">
        <property type="entry name" value="Uncharacterised_CE1759"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04037">
        <property type="entry name" value="LLM_duo_CE1759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="2"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ14857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="196" mass="20573" checksum="86C7D9890942144E" modified="2017-04-12" version="1">MTRIVVISGGLGTPSSTRVLGDLIVARLREELAGDGDLEVSVAELRELAHPIVDAMLTGFPTGELARVVDDVADADALVVVSPTFSASMSGLVKSFFDILEPDTLRGKPVLMAATGGTERHSLMLDFAMRPLFSYLGAEPVRTAIFAATSDFGGPGSAALGRRVRDGAADLARALTSAPRQREPEGFVDFETLLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIJ9</accession>
    <name>A0A1Q2CIJ9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Daunorubicin resistance protein DrrC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_14540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14540"/>
    <dbReference type="EnsemblBacteria" id="AQP45875">
        <property type="protein sequence ID" value="AQP45875"/>
        <property type="gene ID" value="RPIT_14540"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14540"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="2">
        <location>
            <begin position="481"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="521"/>
            <end position="528"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="794" mass="85082" checksum="CE98C761520BB4C8" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIM2</accession>
    <name>A0A1Q2CIM2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45988">
        <property type="protein sequence ID" value="AQP45988"/>
        <property type="gene ID" value="RPIT_02995"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02995"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="DUF4112"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35519">
        <property type="entry name" value="PTHR35519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13430">
        <property type="entry name" value="DUF4112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="146" mass="15730" checksum="DB89E23C31CC6625" modified="2017-04-12" version="1">MTRAFSYVLDDLVQVPGTQVRIGVDPLLSLIPWAGTAVGAAFGGVVLIDAIRLRAPVPVVARMVGNSVVDWLLGMVPFVGALFDVTFRANKKNLRLLNRTIENRELVKKASLRYWIAVGGLILLVMAVMIAIPVAILLGLDALVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIM4</accession>
    <name>A0A1Q2CIM4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_01375</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01375"/>
    <dbReference type="EnsemblBacteria" id="AQP45954">
        <property type="protein sequence ID" value="AQP45954"/>
        <property type="gene ID" value="RPIT_01375"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01375"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="140" mass="15159" checksum="EC5E64D389144813" modified="2017-04-12" version="1">MSGGLPATALACLGTDQEVNLAGLPREPTIVNLWAQWCAPCREEAPFLREGLAELDGVNFVGVNYNDPKLDWAVEFAGLVGWIYPHVIDQDKTLQSQLRVPGLPTTYFVSEDGSIAGVHAGPFESTAQLRELASEYLGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIU8</accession>
    <name>A0A1Q2CIU8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Shikimate_dh_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06220"/>
    <dbReference type="EnsemblBacteria" id="AQP46049">
        <property type="protein sequence ID" value="AQP46049"/>
        <property type="gene ID" value="RPIT_06220"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06220"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004764">
        <property type="term" value="F:shikimate 3-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022893">
        <property type="entry name" value="Shikimate_DH_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089">
        <property type="entry name" value="PTHR21089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shikimate_dh_N" evidence="1">
        <location>
            <begin position="6"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="270" mass="28002" checksum="F5263A744C76D416" modified="2017-04-12" version="1">MRRAGVVGDPAAHSLSPAIHRAGYEAHGLSWAYDAFTVPPDELEPFIAQRAGDPAWAGLSVTAPHKEAALSFGEADEPTRLVGAGNTIVFGPGPRVYNTDVPGFVRAWRARGLEPPRTAAVVGNGATARSIVLALAGLGTREVTVIARDPGRASALVELIRALGLAAAVSLLGEPVESVDLVANTIPAAATEPHAQSLAGAGRVVFDVVYDPWPTPLGRAASAEGVVALNGLDLLAGQAVDQFYLLTGHTVTFDACRSAAERELRRRGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIV8</accession>
    <name>A0A1Q2CIV8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Choline transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_06200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BCCT transporter (TC 2.A.15) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06200"/>
    <dbReference type="EnsemblBacteria" id="AQP46047">
        <property type="protein sequence ID" value="AQP46047"/>
        <property type="gene ID" value="RPIT_06200"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06200"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071705">
        <property type="term" value="P:nitrogen compound transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018093">
        <property type="entry name" value="BCCT_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000060">
        <property type="entry name" value="BCCT_transptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30047">
        <property type="entry name" value="PTHR30047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02028">
        <property type="entry name" value="BCCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00842">
        <property type="entry name" value="bcct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01303">
        <property type="entry name" value="BCCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="248"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="286"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="333"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="470"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="501"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="604"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="613"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP46047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="638" mass="68567" checksum="8FCC2E49656D1816" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIW1</accession>
    <name>A0A1Q2CIW1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ectoine/hydroxyectoine ABC transporter ATP-binding protein EhuA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_02890</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02890"/>
    <dbReference type="EnsemblBacteria" id="AQP45985">
        <property type="protein sequence ID" value="AQP45985"/>
        <property type="gene ID" value="RPIT_02890"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02890"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015424">
        <property type="term" value="F:ABC-type amino acid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030679">
        <property type="entry name" value="ABC_ATPase_HisP-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039085">
        <property type="entry name" value="ABC_ATPase_HisP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="250" mass="27233" checksum="75AA0BD31651B1F0" modified="2017-04-12" version="1">MVEVSGVHKFFGDLHVLKGVDLTVGRGEVCVLLGPSGSGKSTLIRCINELEQISAGRLSVDGELMGLREKDGVLHRRSDKEIAQQRSKIGMVFQRFNLFPHLTALGNVMEAPRQVRGLSRSAAERLAREQLERVGLSDRADHYPAQLSGGQQQRVAIARALAMGPELMLFDEPTSALDPELVGEVLAVMKELAASGMTMIVVTHEVGFAREVADQVVFMDDGLILEAGRPGEVIDAPQHPRTQDFFGKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ12</accession>
    <name>A0A1Q2CJ12_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nucleoside triphosphate pyrophosphatase</fullName>
            <ecNumber evidence="2">3.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Nucleotide pyrophosphatase</fullName>
            <shortName evidence="2">Nucleotide PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09665</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + H2O = a 2'-deoxyribonucleoside 5'-phosphate + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:44644"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:65317"/>
            <dbReference type="EC" id="3.6.1.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-phosphate + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23996"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="EC" id="3.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Maf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.9" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09665"/>
    <dbReference type="EnsemblBacteria" id="AQP46109">
        <property type="protein sequence ID" value="AQP46109"/>
        <property type="gene ID" value="RPIT_09665"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09665"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036218">
        <property type="term" value="F:dTTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035529">
        <property type="term" value="F:NADH pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00555">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00528">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="PTHR43213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02545">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006305">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00172">
        <property type="entry name" value="maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="201" mass="21692" checksum="DE4F4A324F8B6FDA" modified="2017-04-12" version="1">MTMRLILASKSPARLFVLKRAGLHPEVIVSGFDEHQIRDPSPTSLAMRLAEGKGTAVLNAQDGEFVLLACDSVLEFEGRAHGKPGTAERAVERWKRMRGRSGILHTGHFVAVRRDGALQTQLRVGSTEVDFADLSDEEIEAYAATGEPQRVAGGFTIDGRGGAFVTAVHGDPYNVIGVSLPLFRQMVIDAGVAWQSLWAGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ36</accession>
    <name>A0A1Q2CJ36_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Septum formation initiator family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10695"/>
    <dbReference type="EnsemblBacteria" id="AQP46127">
        <property type="protein sequence ID" value="AQP46127"/>
        <property type="gene ID" value="RPIT_10695"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10695"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007511">
        <property type="entry name" value="DUF501"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37163">
        <property type="entry name" value="PTHR37163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04417">
        <property type="entry name" value="DUF501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP46127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="165" mass="17597" checksum="A92FABA6A830B211" modified="2017-04-12" version="1">MMSKPTEADLAAVEAQLGREPRGVEEVAWRCPCGKPGVVKTAPRLPNGTPFPTTYYLTCQRATSGCSTLEASGLMTEMSERLTQDEELAARYRAAHEAYLADRAELGHVEEIDGISAGGMPTRVKCLHVLVGHSLAAGPGVNPLGDEALEKLGEFWATPCLGEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ55</accession>
    <name>A0A1Q2CJ55_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Protein GrpE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">HSP-70 cofactor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">grpE</name>
        <name evidence="7" type="ORF">RPIT_11925</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 5">Belongs to the GrpE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11925"/>
    <dbReference type="EnsemblBacteria" id="AQP46147">
        <property type="protein sequence ID" value="AQP46147"/>
        <property type="gene ID" value="RPIT_11925"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11925"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_coiled_coil"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="PTHR21237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="SSF51064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="SSF58014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01071">
        <property type="entry name" value="GRPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP46147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="174" mass="19000" checksum="1E520B4BD84D5BC2" modified="2017-04-12" version="1">MDEGVDQAPSSEAAAETPTDRSDSTEQPSGDDRTAELEALVAERTLDLQRLQAEYVNYKKRVDRDRDLARQAGVEAVVSDLMPVLDAITLAKQHDDVAGGFKMVIDELEKVTTKHGLVTFGEVGEEFDPNLHDALMAVPLDEPVTVTTVSQVMQQGYQLKGRVIRPARVAVANP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBD6</accession>
    <name>A0A1Q2CBD6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00110</name>
        <name evidence="3" type="ORF">SAMN05428934_10923</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ04971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43422">
        <property type="protein sequence ID" value="AQP43422"/>
        <property type="gene ID" value="RPIT_00110"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ04971">
        <property type="protein sequence ID" value="SDZ04971"/>
        <property type="gene ID" value="SAMN05428934_10923"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00110"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ04971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="76" mass="8432" checksum="02522BD82AC0BA51" modified="2017-04-12" version="1">MSVKKKFENLPGWLKAIMAVGGTADVVLRVVAMIDIIKRDATEINGPKKVWIPALSAVSSMGILPAAYFRWGRRKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBF1</accession>
    <name>A0A1Q2CBF1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_040284068.1">
        <property type="nucleotide sequence ID" value="NZ_CP019605.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43428">
        <property type="protein sequence ID" value="AQP43428"/>
        <property type="gene ID" value="RPIT_00150"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00150"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="92" mass="9987" checksum="1CA8357C49F5B0C9" modified="2017-04-12" version="1">MMTMPRTVDEILQHADELAARFESYEPNPDDELDAGAVALLRAAVAERSEAERHVIDAIRTAREAGMPWSAIGAFVGTSGEAARQRYASKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBF8</accession>
    <name>A0A1Q2CBF8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43444">
        <property type="protein sequence ID" value="AQP43444"/>
        <property type="gene ID" value="RPIT_00260"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00260"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="353" mass="38751" checksum="2A2B2ED32C9257C7" modified="2017-04-12" version="1">MEFPLVELDDAKPLTLPEIASITPAQPGHDHTILLALSNGRTLVTLSPSENFEEAAFVKSNRVGLLRDDGTVDLFADTSNIRPDGRPRQTYAGDINEQWVVWMETSSDNMYESNWRLFAQELDGGKPILVAAAEDQRKATTEFLPLAGGDPFPRLSEGLVWWWTAHEQPDGTFQPRILAADPAGGEPKEMLALSAQLSPVTGGIVAVTLSEAEDHPQTGIVRIDTDGTVTELVRFTQDSEASWGAQRLASSGNIVAMSTGEAVLIMDTSATPIAQIPIPNDREIWDLDVCAGKVVFTPYKPEETDQVAVYDTTTNTLQTIHVPRAETDNYCSDQRISWSQNENNWTSNTIAIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBG7</accession>
    <name>A0A1Q2CBG7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fatty acid-binding-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00310</name>
        <name evidence="3" type="ORF">SAMN05428934_10516</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY83804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00310"/>
    <dbReference type="EnsemblBacteria" id="AQP43450">
        <property type="protein sequence ID" value="AQP43450"/>
        <property type="gene ID" value="RPIT_00310"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY83804">
        <property type="protein sequence ID" value="SDY83804"/>
        <property type="gene ID" value="SAMN05428934_10516"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00310"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07828">
        <property type="entry name" value="lipocalin_heme-bd-THAP4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045165">
        <property type="entry name" value="Nitrobindin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014878">
        <property type="entry name" value="THAP4-like_heme-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15854">
        <property type="entry name" value="PTHR15854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08768">
        <property type="entry name" value="THAP4_heme-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="SSF50814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THAP4_heme-bd" evidence="1">
        <location>
            <begin position="5"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY83804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="158" mass="17319" checksum="FBE3039AB169C96F" modified="2017-04-12" version="1">MHVNLLPAAALAGTYVGLGRGEYPTIEGFEYREELTFADVGKPFLQYVQRTWSADGERPMHTESGYLRIGEGGHIEMTIAQPMGQTESCEGTLTVEDGVLTLTLNAKVTNTTTAKVVHATKRTYHLVGDQLATTFDMEAVGEEMGRHLTSTLKRVATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBH0</accession>
    <name>A0A1Q2CBH0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Two-component system, OmpR family, response regulator MprA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_00330</name>
        <name evidence="6" type="ORF">SAMN05428934_10520</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY83917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00330"/>
    <dbReference type="EnsemblBacteria" id="AQP43452">
        <property type="protein sequence ID" value="AQP43452"/>
        <property type="gene ID" value="RPIT_00330"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY83917">
        <property type="protein sequence ID" value="SDY83917"/>
        <property type="gene ID" value="SAMN05428934_10520"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00330"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="127"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="127"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY83917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="228" mass="25483" checksum="63B91E4B50AC87DF" modified="2017-04-12" version="1">MQILVVDDDQAVRDSLARSLTYSGDEVVTAADGVEALAKLVGYTPDAIIMDVMMPRLDGLETTRMLRQGGNDTPILILTARDAVGDRVDGLDAGADDYMVKPFALDELLARLRALTRRSKPSTETETKVLTFQDVTLDTQHREVTRAGQHISLTRTEFALLQVFMEHPRRVLERNTLLNEVWGFEFPTTANSLEVYIGYLRRKTEAGGKPRLIHTVRGIGYVLRETPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBJ4</accession>
    <name>A0A1Q2CBJ4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 15">Argininosuccinate synthase</fullName>
            <ecNumber evidence="6 15">6.3.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14 15">Citrulline--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">argG</name>
        <name evidence="16" type="ORF">RPIT_00465</name>
        <name evidence="17" type="ORF">SAMN05428934_10547</name>
    </gene>
    <organism evidence="16 18">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 18" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1T</strain>
        </source>
    </reference>
    <reference evidence="17 19" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">RP1</strain>
        </source>
    </reference>
    <reference evidence="16" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10932"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 15">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the argininosuccinate synthase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.5" evidence="6 15"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY84687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00465"/>
    <dbReference type="EnsemblBacteria" id="AQP43476">
        <property type="protein sequence ID" value="AQP43476"/>
        <property type="gene ID" value="RPIT_00465"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY84687">
        <property type="protein sequence ID" value="SDY84687"/>
        <property type="gene ID" value="SAMN05428934_10547"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00465"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00113"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004055">
        <property type="term" value="F:argininosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.400">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00581">
        <property type="entry name" value="Arg_succ_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Arg_succ_synth_type2_subfam"/>
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        <property type="entry name" value="Arginosuc_synth"/>
    </dbReference>
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        <property type="entry name" value="Arginosuc_synth_CS"/>
    </dbReference>
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        <property type="entry name" value="AS_cat/multimer_dom_body"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024073">
        <property type="entry name" value="AS_multimer_C_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11587">
        <property type="entry name" value="PTHR11587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00764">
        <property type="entry name" value="Arginosuc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF69864"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00032">
        <property type="entry name" value="argG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00564">
        <property type="entry name" value="ARGININOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00565">
        <property type="entry name" value="ARGININOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 15" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="13 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="12 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="17"/>
            <end position="25"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
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        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
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        </location>
    </feature>
    <feature type="binding site" evidence="15">
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        </location>
    </feature>
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        <location>
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        </location>
        <ligand>
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        </ligand>
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        <location>
            <position position="192"/>
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        <ligand>
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        </ligand>
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        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        <location>
            <position position="201"/>
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        <ligand>
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        </ligand>
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        <location>
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        <location>
            <position position="280"/>
        </location>
        <ligand>
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        </ligand>
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        <source>
            <dbReference type="ARBA" id="ARBA00001891"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00009088"/>
        </source>
    </evidence>
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        </source>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="473" mass="52264" checksum="660E81B0C7AFD685" modified="2017-04-12" version="1">MSKVLTSLPVGERVGIAFSGGLDTSVAVAWMRELGAVPCTYTANIGQYDEPDIDSVPGRALQYGAELSRMVDCRSQLVEEGLSALACGAFHIRSAGKAYFNTTPIGRAVTGTLLVRAMVEDDVFIWGDGSTYKGNDIERFYRYGLMANPMLRIYKPWLDEEFVHQLGGRDEMSQWLLERDLPYRDSKEKAYSTDANIWGATHEAKTLEDLDVSLETVQPIMGVKYWDPSVAIETEDVSVRFELGRPVAINGTRFDDPVALVMEANAVGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLWIAYERLLTAIHNEDTLANYRTEGLRLGRLLYEGRWLDPQSLMLRESIQRWVASAVTGEVDIRLRRGDDYTILDTRGPHLSYQPHKLSMERVEDAAFGPTDRIGQLTMRNLDIADSREKLELYAAQGTLLAEHQDLIGRLEAGGAAAIAELGATGPSEVDDAVASSSFDTGTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBJ7</accession>
    <name>A0A1Q2CBJ7_9ACTN</name>
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        <submittedName>
            <fullName evidence="3">PhnB protein</fullName>
        </submittedName>
        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00505</name>
        <name evidence="3" type="ORF">SAMN05428934_10554</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
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            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
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                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="RPIT_00505"/>
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        <property type="gene ID" value="SAMN05428934_10554"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF54593"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyoxalase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY84868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="146" mass="15761" checksum="E40AA58FD2FB3764" modified="2017-04-12" version="1">MATLATYIAYEGVGSTKTAFEHYRDIFGGELKVLTYGDVPPMEGMPFTPDPNSVAHATLELPGGTIAGGDAMPGESYVVKDTVYSMLYTLDDVEEARGYIQKMVDGGGSINMPFEPAPWGGHYGQVFDKFGVMWSFDVGGTDQPQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBL3</accession>
    <name>A0A1Q2CBL3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Predicted O-methyltransferase YrrM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_00190</name>
        <name evidence="5" type="ORF">SAMN05428934_1096</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ04627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00190"/>
    <dbReference type="EnsemblBacteria" id="AQP43435">
        <property type="protein sequence ID" value="AQP43435"/>
        <property type="gene ID" value="RPIT_00190"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ04627">
        <property type="protein sequence ID" value="SDZ04627"/>
        <property type="gene ID" value="SAMN05428934_1096"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00190"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51682">
        <property type="entry name" value="SAM_OMT_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ04627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="199" mass="22047" checksum="428F7D938A058718" modified="2017-04-12" version="1">MSSTTRPTPDGSSLRQTLAVLTAAAEDLGFVQSSEGDLGRLLRLLVASRPGGSFLELGTGVGYGAAWLLDGMDADSRLVSVELEDDLQRIARATFDDDPRVEWVLGDGSEWLREAVARPERFDVVFADTWPGKYHDRDLAMELVKPHGWFVLDDLYPQPGWPDGHQANVDRLIADMQSVDGWRTEFLPWGSGLMLCVRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBM3</accession>
    <name>A0A1Q2CBM3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00670</name>
        <name evidence="2" type="ORF">SAMN05428934_10587</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY85749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00670"/>
    <dbReference type="EnsemblBacteria" id="AQP43513">
        <property type="protein sequence ID" value="AQP43513"/>
        <property type="gene ID" value="RPIT_00670"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY85749">
        <property type="protein sequence ID" value="SDY85749"/>
        <property type="gene ID" value="SAMN05428934_10587"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00670"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012551">
        <property type="entry name" value="DUF1707"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08044">
        <property type="entry name" value="DUF1707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY85749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="211" mass="22587" checksum="E7C0E961D1FD8734" modified="2017-04-12" version="1">MPNVPDRLEVLRCADQDREVVAQLLNTAYTDGRLTIDEHTDRIAAAYDAKTFGDLNRLTVDLVPPPTPRPAHFAHPVSHNGAGPVAPGAYTGGNAMLSTLKPGVIGCLAHDVTLNAWLGEIRLDLVGTAFASRSTTLRLGGFMCDIKIRVPEGVTINTSGLTSVLSDSKIDGVVGHPDGVVLNLVGTIVMGDVKVLGPQCRNPRRYERFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBS5</accession>
    <name>A0A1Q2CBS5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00950"/>
    <dbReference type="EnsemblBacteria" id="AQP43563">
        <property type="protein sequence ID" value="AQP43563"/>
        <property type="gene ID" value="RPIT_00950"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00950"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="104"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="322" mass="36033" checksum="FDA7608F2CFD5782" modified="2017-04-12" version="1">MSAYDDWRRGRRFDSPPPPARDVIPYIQESVFLHHPDLVVELPEPDRRDLYGLPGNEATSGLTPITELFNGTPHPGSEVRENAVVGMMKLIGLRSHQREAGSFVLDPQPVDDGPGWQDWLGTHKLLKTRRRIRFRTVPEGSPDEARRRVRRIAEHEMRVMQHLSHDAVLRPEDLVDSDLGPGLVYPYDPAWQRLDLWLAGRPTLGFDDQLALVRQVAEALAYAHGKNVVHRGLNPRAVLVNTDRDGRLQVKVGDWQGVGRTDEATHTEATRGVTQLADVLAGEIPLADRWARTFCYQTVISPALGSDGASAWVAADRVVRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBX5</accession>
    <name>A0A1Q2CBX5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01155</name>
        <name evidence="3" type="ORF">SAMN05428934_105181</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY88254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01155"/>
    <dbReference type="EnsemblBacteria" id="AQP43600">
        <property type="protein sequence ID" value="AQP43600"/>
        <property type="gene ID" value="RPIT_01155"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY88254">
        <property type="protein sequence ID" value="SDY88254"/>
        <property type="gene ID" value="SAMN05428934_105181"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01155"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY88254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="292" mass="30766" checksum="04DDDCD6F87AC947" modified="2017-04-12" version="1">MTHQGLATKAVGAIMAAALIGGCTAAPTNSPTPVLAPITRRDPGLDDAGQPLRDDQGRLLHRTHVVTTKPVTVFDIRQTDGPTLPDPKIGDGALLTGEAPAGLWDRLQGLLEERGFDVRRGADLGGANGVTDFTQRLVTIRDDVDDAQAVKTPAHEAGHVLLHQDQGSRDCRGIVEVEAESVAYMVTSAHGLDSSQYTFNYVAGWALNAVTEQRDLAEILRSTGQRVIGAAALILQATQPAPTITDGALDALESEVRTQVDPTRWEVAPAVAEPPPQVSPPSRAVPAPALSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC18</accession>
    <name>A0A1Q2CC18_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01545"/>
    <dbReference type="EnsemblBacteria" id="AQP43658">
        <property type="protein sequence ID" value="AQP43658"/>
        <property type="gene ID" value="RPIT_01545"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01545"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000667">
        <property type="entry name" value="Peptidase_S13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30023">
        <property type="entry name" value="PTHR30023"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02113">
        <property type="entry name" value="Peptidase_S13"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00922">
        <property type="entry name" value="DADACBPTASE3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00666">
        <property type="entry name" value="PBP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="480" mass="48844" checksum="ACBB7E72A3CA4B44" modified="2017-04-12" version="1">MAVRSRNRAVQWVVAWLIVGILLGGGFAAAVYSEQLLAAAGLTRSGAPSTIDPELFAPEPTPTADAPTPAGTGLAAAAALPEPGPLPDRLVLEERLNSLDRSELVAQEGATVAIAYEVVDVATGEIVAANGQDLPLIPASNTKTLTALAVMNAFDGSETFATRVLQPAAGQVVLVGGGDPLLRSTPADAGYPQPASTAELAAATAEALLASGQTSVTLGYDASLFTDPGWNATWPDNYRDQVTQLSSLWVDEGRGPDGGPRSRNPALSAAETFAAQLTAAGVAVAGEPTAVPASGAEVARVESLPVHVLVETAMTRSNNSFTEVLGFQLALQTGHPATFEGSVAAIEEQLTALGLWRQGAVLYDASGLSRSNLVTAGMLAEAVRAMASEPRLSVILDGLPTAGVTGTLADRFADDVSSPARGVARAKTGTLSFVSTLAGTTLTADGRLVAFAFIINGPPNGWAARVWADQAAGVVAACGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC65</accession>
    <name>A0A1Q2CC65_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Folate-binding protein YgfZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_01810</name>
        <name evidence="5" type="ORF">SAMN05428934_108110</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ03046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01810"/>
    <dbReference type="EnsemblBacteria" id="AQP43699">
        <property type="protein sequence ID" value="AQP43699"/>
        <property type="gene ID" value="RPIT_01810"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ03046">
        <property type="protein sequence ID" value="SDZ03046"/>
        <property type="gene ID" value="SAMN05428934_108110"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01810"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCV_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045179">
        <property type="entry name" value="YgfZ/GcvT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017703">
        <property type="entry name" value="YgfZ/GcvT_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22602">
        <property type="entry name" value="PTHR22602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="SSF101790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03317">
        <property type="entry name" value="ygfZ_signature"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="GCV_T" evidence="3">
        <location>
            <begin position="15"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ03046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="309" mass="33245" checksum="F4040BEBA5963892" modified="2017-04-12" version="1">MPVLLDSGPDEGLAWHYGNPVTEARSLVAGNGVVDLHNREIVEISGPDRLSWLHSLTTQHLSALTPGDSTTALILSPTGHIEHVLHGVDDGTSFLAWTEPSRADALVDFLLRMRFAMRVEVARRTDLTLAWTGHRVDLDPAWRSRRSEVGGSEVFLPAGESLEANVGTWAFDAQRIAAGVPRIFVDTDFKTIPNEIGLMGTHLDKGCYRGQETVARVHTLGRPPRRLVQLHLDGSLSSLPEVGDPIEFGGRVVGFVGSSARHHELGPVALGLVKRNVPVDAEVLAGGIAAAQEALVDPDVGLHVRPVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCF5</accession>
    <name>A0A1Q2CCF5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_02255</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02255"/>
    <dbReference type="EnsemblBacteria" id="AQP43781">
        <property type="protein sequence ID" value="AQP43781"/>
        <property type="gene ID" value="RPIT_02255"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02255"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="1626" mass="169235" checksum="C9E3D5427C1DA0FD" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCF8</accession>
    <name>A0A1Q2CCF8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Molybdenum cofactor biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02345"/>
    <dbReference type="EnsemblBacteria" id="AQP43799">
        <property type="protein sequence ID" value="AQP43799"/>
        <property type="gene ID" value="RPIT_02345"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02345"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00886">
        <property type="entry name" value="MogA_MoaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="1">
        <location>
            <begin position="9"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="176" mass="18516" checksum="E152E936FF76EA62" modified="2017-04-12" version="1">MAVMSYSAAVITCSDRAAASVYEDRSGPVLREALAELGFEVADGVVVPDHPEQIRRAIQDAVREGARVIFTTGGTGISPTDLTVEITRELMAYEVPGLMEEVRRVGSQKEPRALLSRGLAAILALPGQQRAIIVNAPGSRGGARDSVEVVGPLLHHIVEQLDGSDHPTDAPGAGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCI5</accession>
    <name>A0A1Q2CCI5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytochrome c nitrite reductase small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_02425</name>
        <name evidence="6" type="ORF">SAMN05428934_10183</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY24782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02425"/>
    <dbReference type="EnsemblBacteria" id="AQP43814">
        <property type="protein sequence ID" value="AQP43814"/>
        <property type="gene ID" value="RPIT_02425"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY24782">
        <property type="protein sequence ID" value="SDY24782"/>
        <property type="gene ID" value="SAMN05428934_10183"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02425"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3820.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005126">
        <property type="entry name" value="NapC/NirT_cyt_c_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038266">
        <property type="entry name" value="NapC/NirT_cytc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017571">
        <property type="entry name" value="NrfH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03264">
        <property type="entry name" value="Cytochrom_NNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03153">
        <property type="entry name" value="cytochr_NrfH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_NNT" evidence="4">
        <location>
            <begin position="18"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY24782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="161" mass="17983" checksum="22CBDFB3CB6AD7FE" modified="2017-04-12" version="1">MTLIQRIGAWFTRPRILMAAAIFVVGSLIGVGLFTFVYAKGISYLGSDPAACVNCHVMERQYSAWISGSHSNVAGCNDCHAPHDNIIHKYYVKADNGFWHGLKFTTGWYPENIEIRESNRKVTNEACLYCHADFTSTMRMTSGSEQINCTSCHVNVGHKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCQ2</accession>
    <name>A0A1Q2CCQ2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Flagellum-specific peptidoglycan hydrolase FlgJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_02820</name>
        <name evidence="4" type="ORF">SAMN05428934_101164</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY27100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02820"/>
    <dbReference type="EnsemblBacteria" id="AQP43877">
        <property type="protein sequence ID" value="AQP43877"/>
        <property type="gene ID" value="RPIT_02820"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY27100">
        <property type="protein sequence ID" value="SDY27100"/>
        <property type="gene ID" value="SAMN05428934_101164"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02820"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002901">
        <property type="entry name" value="MGlyc_endo_b_GlcNAc-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01832">
        <property type="entry name" value="Glucosaminidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00047">
        <property type="entry name" value="LYZ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544418" evidence="1">
        <location>
            <begin position="28"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="LYZ2" evidence="2">
        <location>
            <begin position="22"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY27100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="350" mass="37585" checksum="70CA6544B6479249" modified="2017-04-12" version="1">MRWFKLAVVVVLIALATAASVTNPARASVQQDFIAKLVEGARENERRTGIPASVTIGMAALESGWGRSTMAGTMTVNGTVYKVNTLFNIKCTSTPSPYQTGCVPVSSYEYRADGTKYLKVSNFRTYASWADSMLDFGRFLTTLSRYAPAFDYTRYPDQFVTEVRRAGYATDPKYSELVISIMRSYSLYQYNVSGAGPGYPSGADTDTPVVVDPVFKSGSDFPALSRGSRGTVVESLQTLLNAAGSTLLVDGSYGALTEGAVKTYQSSQGLPATGAVDDQTWSRLLPSLRAGDSGERVSALQLELKAEGLAVTVNGTFDPATEAAVRSFQERQRIKPNGAVGLATWARLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCS5</accession>
    <name>A0A1Q2CCS5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsS</name>
        <name evidence="7" type="ORF">RPIT_03060</name>
        <name evidence="8" type="ORF">SAMN05428934_101213</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY28657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03060"/>
    <dbReference type="EnsemblBacteria" id="AQP43918">
        <property type="protein sequence ID" value="AQP43918"/>
        <property type="gene ID" value="RPIT_03060"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY28657">
        <property type="protein sequence ID" value="SDY28657"/>
        <property type="gene ID" value="SAMN05428934_101213"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03060"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_S15/S19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_S19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005732">
        <property type="entry name" value="Ribosomal_S19_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_S19_S15_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="PTHR11880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="SSF54570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01050">
        <property type="entry name" value="rpsS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY28657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="93" mass="10726" checksum="FBB07D056E7DCA25" modified="2017-04-12" version="1">MPRSLKKGPFVDDHLQKKVDVQNEKGTKNVIKTWSRRSMIIPEMLGHTIAVHDGRKHIPVFVTESMIGHKLGEFAPTRTFKGHVKDDKKARRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCW1</accession>
    <name>A0A1Q2CCW1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein translocase subunit SecY</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secY</name>
        <name evidence="11" type="ORF">RPIT_03190</name>
        <name evidence="12" type="ORF">SAMN05428934_101239</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03190"/>
    <dbReference type="EnsemblBacteria" id="AQP43944">
        <property type="protein sequence ID" value="AQP43944"/>
        <property type="gene ID" value="RPIT_03190"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29492">
        <property type="protein sequence ID" value="SDY29492"/>
        <property type="gene ID" value="SAMN05428934_101239"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03190"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01465">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026593">
        <property type="entry name" value="SecY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="PTHR10906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="SSF103491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00755">
        <property type="entry name" value="SECY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP43944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY29492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="438" mass="47771" checksum="591339F496EC8E8D" modified="2017-04-12" version="1">MLSAFANALKTPDLRKKILFTLGIIVIFRLGSTIPSPNVNIARIDECLALATAGESAGIYNMVNLFSGGALLQLTIFALGIMPYITASIILQLLTVVIPRLEALKKEGASGTAKITEYTRYLTLVLAVLNATAFVTLARTGQLFPGCDGILYTNELFPLITMVLVMTAGTGIIMWMGELITERGVGNGMSIMIFTQIAASFPAGLWAIKQSHPGAVGWFLFFLVIGIGLVVMLGIIWVEQGQRRIPVQYAKRMVGRRLVGGSTTYIPLKVNQSGVIPVIFATSILYLPVLWATFRPEGAVSVWIQQNFAGQGMLSSFWYNLVQFVLIIAFCYFYVSITFNPEEVSDNMKKYGGFIPGIRAGKPTERYLAYVLSRLTAPGSLYLATIALIPTIAFMAVGANQNFPFGGTSILIIVGVGLDTVKKIESQLQQRNYEGFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCX8</accession>
    <name>A0A1Q2CCX8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Translation initiation factor IF-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">infA</name>
        <name evidence="5" type="ORF">RPIT_03345</name>
        <name evidence="6" type="ORF">SAMN05428934_101269</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IF-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_068749455.1">
        <property type="nucleotide sequence ID" value="NZ_FNPU01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03345"/>
    <dbReference type="EnsemblBacteria" id="AQP43969">
        <property type="protein sequence ID" value="AQP43969"/>
        <property type="gene ID" value="RPIT_03345"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30397">
        <property type="protein sequence ID" value="SDY30397"/>
        <property type="gene ID" value="SAMN05428934_101269"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03345"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04451">
        <property type="entry name" value="S1_IF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00075">
        <property type="entry name" value="IF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004368">
        <property type="entry name" value="TIF_IF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33370">
        <property type="entry name" value="PTHR33370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00008">
        <property type="entry name" value="infA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S1-like" evidence="4">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY30397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="73" mass="8288" checksum="9B1BD692BF539E8E" modified="2017-04-12" version="1">MAKKEGALELEGTVVEALPNAMFRVELANGHKVLTTISGKMRQHYIRILPADRVVVELSPYDLTRGRIVYRHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCZ0</accession>
    <name>A0A1Q2CCZ0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplQ</name>
        <name evidence="7" type="ORF">RPIT_03375</name>
        <name evidence="8" type="ORF">SAMN05428934_101275</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Contacts protein L32.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the bacterial ribosomal protein bL17 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03375"/>
    <dbReference type="EnsemblBacteria" id="AQP43974">
        <property type="protein sequence ID" value="AQP43974"/>
        <property type="gene ID" value="RPIT_03375"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30585">
        <property type="protein sequence ID" value="SDY30585"/>
        <property type="gene ID" value="SAMN05428934_101275"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03375"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01368">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000456">
        <property type="entry name" value="Ribosomal_L17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036373">
        <property type="entry name" value="Ribosomal_L17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413">
        <property type="entry name" value="PTHR14413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01196">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64263">
        <property type="entry name" value="SSF64263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00059">
        <property type="entry name" value="L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01167">
        <property type="entry name" value="RIBOSOMAL_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="122"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="144"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY30585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="189" mass="20422" checksum="D00460454DC5D199" modified="2017-04-12" version="1">MPKPTKGPRLGGSPTHERIMMRNLATQLFQHGRITTTETKARRVQPLAEKLITKAKRGDLHSRRLVLESITDVAVVKHLFDEIAPTMAEREGGYTRITKIGPRKGDNAPLAVIEIITEAVTPKPKSAKAAPKAEAKADETETPVEESEVAEAPEQEIAEDEAAAEATEAEADETAAAEPTAPAETDQTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD21</accession>
    <name>A0A1Q2CD21_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03670</name>
        <name evidence="3" type="ORF">SAMN05428934_101336</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY32418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44022">
        <property type="protein sequence ID" value="AQP44022"/>
        <property type="gene ID" value="RPIT_03670"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY32418">
        <property type="protein sequence ID" value="SDY32418"/>
        <property type="gene ID" value="SAMN05428934_101336"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03670"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544423" evidence="1">
        <location>
            <begin position="36"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY32418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="219" mass="22633" checksum="905DE23951FF3212" modified="2017-04-12" version="1">MTEPTKSGITRRTVAKGAAWSVPVLAVAGAAPAYAMSPTTTLPPCVTYTFAPTACKWPGSNNLWSYYLVLKICNTCQTTQTINFTITRLQNNSGKVFRDCGAETLPITINETLEAGECTEIILGDFSSANADGSGSSAAFIEAYSGNIKLFSVKAPPTDCEAPLVNSCIAPTTTVAPTTTVAPTTTVAPTTTVAPTTTVAPTTTVAPTTTVAPTTTVQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD90</accession>
    <name>A0A1Q2CD90_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 14">Pyruvate kinase</fullName>
            <ecNumber evidence="5 14">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">RPIT_04080</name>
        <name evidence="18" type="ORF">SAMN05428934_101419</name>
    </gene>
    <organism evidence="17 19">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 19" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">RP1T</strain>
        </source>
    </reference>
    <reference evidence="18 20" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">RP1</strain>
        </source>
    </reference>
    <reference evidence="17" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the pyruvate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="5 14"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY34652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04080"/>
    <dbReference type="EnsemblBacteria" id="AQP44092">
        <property type="protein sequence ID" value="AQP44092"/>
        <property type="gene ID" value="RPIT_04080"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY34652">
        <property type="protein sequence ID" value="SDY34652"/>
        <property type="gene ID" value="SAMN05428934_101419"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04080"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018209">
        <property type="entry name" value="Pyrv_Knase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PTHR11817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="SSF52935"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00110">
        <property type="entry name" value="PYRUVATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 14" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 14 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13 17" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PK" evidence="15">
        <location>
            <begin position="1"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="PK_C" evidence="16">
        <location>
            <begin position="355"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="AQP44092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="SDY34652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="474" mass="51775" checksum="C49C690CC9AECAC9" modified="2017-04-12" version="1">MRRAKIVCTLGPSAETVDRLIELLNAGMNVARLNMSHGDYNEHGTRLKNVRAAAEAVGKTVGVFADLQGPKIRLGRFADDKKVQLEVGDTFTITTDDILGDDHRCSTTYKGLPGDVNVGDHILIDDGKVGLKAVEVTDTDVVCEVTVPGPVSNNKGINLPGVAVSVPALSDKDERDLRWALHQDVDMIALSFVRSGDDIRRVHEIMDEEGRHLPVIAKLEKPQAIANLQEIIDSFDAFMVARGDLGVELPLEEVPLVQKRIIRAARKWAKPVIVATQMLESMITNPRPTRAEASDVANAILDGADAVMLSGETSVGDFPVETVSTMARIVEKTEREGHAEIHIIDWDPHTTGGILAKAAAEVAERIGARYLVAFTKSGDTGRRLSRLRSPIPMLVFSPERATRQTMTLSWGVDTHITPEFTNQEEVVEAVDKHLRDRGMIEVGERIVMLSGSPMGIPGKTNNLRVHKVKELGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDD1</accession>
    <name>A0A1Q2CDD1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Maleylpyruvate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04160</name>
        <name evidence="3" type="ORF">SAMN05428934_101436</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY35189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </evidence>
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</entry>
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        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
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</entry>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6 8">RP1T</strain>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 9">RP1</strain>
        </source>
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    <reference evidence="6" key="3">
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                <person name="Peterson S.W."/>
            </authorList>
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    </dbReference>
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    </evidence>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="532" mass="57575" checksum="D2F39E14020F7598" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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            <dbReference type="PubMed" id="26869509"/>
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        </source>
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    <reference evidence="6 8" key="2">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="5" key="3">
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04450"/>
    <dbReference type="EnsemblBacteria" id="AQP44156">
        <property type="protein sequence ID" value="AQP44156"/>
        <property type="gene ID" value="RPIT_04450"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY36802"/>
        <property type="gene ID" value="SAMN05428934_101496"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04450"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018080">
        <property type="entry name" value="Band_7/stomatin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_HflKC_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF117892"/>
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    </dbReference>
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        <property type="entry name" value="BAND_7"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="4">
        <location>
            <begin position="22"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="349"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="370"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY36802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="391" mass="43236" checksum="FEE43A0A165A3590" modified="2017-04-12" version="1">MPDASLFILIALVVVIVMLLAATLKIIRQQQVALVERLGKFRKALEPGPHLVVPFFDQIRYTLDMREQVVPFPPQGVITEDNLMVSIDSVIYFQIVDPKRAAYEAQDYRSAIEQLTMTTLRNIIGGMDLEAALTSREEINQRLRAVLDEATGKWGIKVNRVELRAIEPPATIRDAMEKGARAERDKRAQILLAEGQRQSMILSAGGDREAAILRAQGDREAAVLRAQADRQAQMLRSEGEAQAITTVFNAIHAGEPDQALLAYQYMQMLPNLAQGDSNKVWIIPSELNDALKGLGQASGSDEVREYVSRAARQFTAPEKVDVHAEIEEHARRDRQRSNETVEKAIADAKALEQNKASRLAGGPAAINQKATPPAQPQDQPEAQPQEDPAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDM1</accession>
    <name>A0A1Q2CDM1_9ACTN</name>
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        <submittedName>
            <fullName evidence="4">Predicted dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_04845</name>
        <name evidence="4" type="ORF">SAMN05428934_101577</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04845"/>
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        <property type="gene ID" value="RPIT_04845"/>
    </dbReference>
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        <property type="gene ID" value="SAMN05428934_101577"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </feature>
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            <end position="321"/>
        </location>
    </feature>
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        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY38800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="331" mass="35900" checksum="7542385E29081F69" modified="2017-04-12" version="1">MSGAIRIGILGAAGITPTSLIEPAHTNPDVELAAVAARDRARAEEFAAEHGIARVVDSYEALVADPDIDAIYIPLPNSHHAAWTIRSLQAGKHVLVEKPFASNAEEAQRVAEVAAASELVVMEAFHYRYHALTRKIIELVELGSIGELQDITATFNINLPDRTNIRYRYDVAGGATMDLGCYPLHLVRSIVGEEPTVTSATYRPSPEDARIDEALTAELEFPSGVTATISSSLLEDEEVQTAVLTGTRGTMEVSGFVKPQEGNWLRVSGENPTMELPTKPTSYEEQLAVFVSAIREGTEVLTDPTDSVKTMRVIDDMYRAAGLTPRETLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDT5</accession>
    <name>A0A1Q2CDT5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05090</name>
        <name evidence="3" type="ORF">SAMN05428934_101624</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY40020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44266">
        <property type="protein sequence ID" value="AQP44266"/>
        <property type="gene ID" value="RPIT_05090"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY40020">
        <property type="protein sequence ID" value="SDY40020"/>
        <property type="gene ID" value="SAMN05428934_101624"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05090"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY40020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="74" mass="8043" checksum="4222F9A257730423" modified="2017-04-12" version="1">MTEQAPAPRKPLPIWAKIARIVAILACLFLFVAAYFVMQGGDGAAEWERLGSSAFGVAVMAVMMLFLGRAQTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDU0</accession>
    <name>A0A1Q2CDU0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_04780</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04780"/>
    <dbReference type="EnsemblBacteria" id="AQP44215">
        <property type="protein sequence ID" value="AQP44215"/>
        <property type="gene ID" value="RPIT_04780"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04780"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PTHR11101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="425" mass="43744" checksum="3F80BA0341F71736" modified="2017-04-12" version="1">MPPELIVLALVVVVALAFDFTNGFHDTGNAMATSIATGALRPKTAVTLSAVLNLIGAFLSVEVALTVTNAVVNIQDSSGAPRPELIGDGGMALLMIILAGLAGAIIWNLLTWLLSLPSSSSHALFGGLVGATMAGLGVNGVKWVGDGTKLDGVVGKVILPALMSPVVAVLVAAVGTWLVFRITRGVAEKYRESGFRWGQIGSASLVSLAHGTNDAQKTMGVITLALIATGAWTDLTAVPFWVKFTCALAIALGTYLGGWRIIRTLGKGLVEIASPQGMAAESSSAAVILASSHMGFALSTTHVATGSILGTGIGKRDATVNWRIAGRMLLAWGITLPAAGLVGAALWVVGHLIGGLPGALVVFSILVAASAWMYQRSKRSAVDHRNVNDEWVELATAQSPGAPAVIPEEPLVIDESAPAAEEVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDZ6</accession>
    <name>A0A1Q2CDZ6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine protein phosphatase PrpC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05420</name>
        <name evidence="3" type="ORF">SAMN05428934_10331</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY65879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05420"/>
    <dbReference type="EnsemblBacteria" id="AQP44321">
        <property type="protein sequence ID" value="AQP44321"/>
        <property type="gene ID" value="RPIT_05420"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY65879">
        <property type="protein sequence ID" value="SDY65879"/>
        <property type="gene ID" value="SAMN05428934_10331"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05420"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PTHR13832"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="23"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY65879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="265" mass="27614" checksum="0CBF5947E5670921" modified="2017-04-12" version="1">MVDSAPRSSAERAHYLRSPAPWVAGASDVGLRHETNEDALGLAVRSEPSHAAVLAVSDGVTTAHGSEVASLVATETVVDELVTRHSKGQVAEQALVHAFAAAQRSVVDASDQTSACTLVAAVIDGRSVSVGNVGDSRAYWIPDAGGVESLTTDDSLAQARIMLGMTRMEAEQSHHSHALTRWLGRESSDATPAVTTLTVDAPGWLLLCTDGLWNYASDPADLADLVRQQASRAQSTDALADALVGWAVAKGGKDNVTVALARIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE22</accession>
    <name>A0A1Q2CE22_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="15">PTS sugar transporter subunit IIABC</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="16">PTS system IIA component, Glc family /PTS system IIB component, Glc family /PTS system IIC component, Glc family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">RPIT_05570</name>
        <name evidence="16" type="ORF">SAMN05428934_10361</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1T</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1</strain>
        </source>
    </reference>
    <reference evidence="15" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY66727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05570"/>
    <dbReference type="EnsemblBacteria" id="AQP44347">
        <property type="protein sequence ID" value="AQP44347"/>
        <property type="gene ID" value="RPIT_05570"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY66727">
        <property type="protein sequence ID" value="SDY66727"/>
        <property type="gene ID" value="SAMN05428934_10361"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05570"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00212">
        <property type="entry name" value="PTS_IIB_glc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036878">
        <property type="entry name" value="Glu_permease_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018113">
        <property type="entry name" value="PTrfase_EIIB_Cys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003352">
        <property type="entry name" value="PTS_EIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013013">
        <property type="entry name" value="PTS_EIIC_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001996">
        <property type="entry name" value="PTS_IIB_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00367">
        <property type="entry name" value="PTS_EIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02378">
        <property type="entry name" value="PTS_EIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55604">
        <property type="entry name" value="SSF55604"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51098">
        <property type="entry name" value="PTS_EIIB_TYPE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01035">
        <property type="entry name" value="PTS_EIIB_TYPE_1_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51103">
        <property type="entry name" value="PTS_EIIC_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="121"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="241"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="270"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="414"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="450"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIB type-1" evidence="13">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIC type-1" evidence="14">
        <location>
            <begin position="112"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIB type-1" evidence="13">
        <location>
            <begin position="509"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphocysteine intermediate; for EIIB activity" evidence="11">
        <location>
            <position position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="AQP44347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="SDY66727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="593" mass="63233" checksum="D839769E6C77D9EE" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE23</accession>
    <name>A0A1Q2CE23_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">1-deoxy-D-xylulose-5-phosphate synthase</fullName>
            <ecNumber evidence="10">2.2.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">1-deoxyxylulose-5-phosphate synthase</fullName>
            <shortName evidence="10">DXP synthase</shortName>
            <shortName evidence="10">DXPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">dxs</name>
        <name evidence="12" type="ORF">RPIT_05620</name>
        <name evidence="13" type="ORF">SAMN05428934_10371</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO2</text>
            <dbReference type="Rhea" id="RHEA:12605"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="10">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the transketolase family. DXPS subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.7" evidence="10"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY66977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05620"/>
    <dbReference type="EnsemblBacteria" id="AQP44356">
        <property type="protein sequence ID" value="AQP44356"/>
        <property type="gene ID" value="RPIT_05620"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY66977">
        <property type="protein sequence ID" value="SDY66977"/>
        <property type="gene ID" value="SAMN05428934_10371"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05620"/>
    <dbReference type="UniPathway" id="UPA00064">
        <property type="reaction ID" value="UER00091"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008661">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052865">
        <property type="term" value="P:1-deoxy-D-xylulose 5-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02007">
        <property type="entry name" value="TPP_DXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00315">
        <property type="entry name" value="DXP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005477">
        <property type="entry name" value="Dxylulose-5-P_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43322">
        <property type="entry name" value="PTHR43322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13292">
        <property type="entry name" value="DXP_synthase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00204">
        <property type="entry name" value="dxs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="11">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="10">
        <location>
            <begin position="114"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="10">
        <location>
            <begin position="146"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="368"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP44356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY66977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="634" mass="68260" checksum="9DB0E02C25F4C023" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE45</accession>
    <name>A0A1Q2CE45_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">ABC-2 type transport system ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_05885</name>
        <name evidence="6" type="ORF">SAMN05428934_103125</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05885"/>
    <dbReference type="EnsemblBacteria" id="AQP44402">
        <property type="protein sequence ID" value="AQP44402"/>
        <property type="gene ID" value="RPIT_05885"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68340">
        <property type="protein sequence ID" value="SDY68340"/>
        <property type="gene ID" value="SAMN05428934_103125"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05885"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY68340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="240" mass="25355" checksum="E594DD8C6D5BE753" modified="2017-04-12" version="1">MITIQNLTKRYGDVLAVDDISFTVSPGNVCGFLGPNGAGKSTTMRCLVGLAEPTGGTALVLGQRYHDLTAPAAQVGTMLDASALHPGRTGLEILTQGAIVLGLPRTRVREVLDLVGLTAKEAKRRVGKYSLGMRQRLGIAHALLGSPSVLVLDEPANGLDPAGIRWMRGLLRDFATRGGTVLLSSHLLHEVQQIADELVMIGQGRIVAHGTLAELLASGDDLEEMFITRTATTSREGALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE65</accession>
    <name>A0A1Q2CE65_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05545"/>
    <dbReference type="EnsemblBacteria" id="AQP44345">
        <property type="protein sequence ID" value="AQP44345"/>
        <property type="gene ID" value="RPIT_05545"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05545"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021443">
        <property type="entry name" value="DUF3093"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11292">
        <property type="entry name" value="DUF3093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="146" mass="16002" checksum="C7A51281FF7FB014" modified="2017-04-12" version="1">MTYRERLHIPWWWGVIGFLFVASIAVVVFFSMDTVPALAVSLLSLVGVGLFLVAYSRTLIAVENGAVRAGRNHLEAAYIGGAEALCGDAARRALGPESDSRAFLFTRPFVRDVVRIEVADTADPHPHWLVSTRRPQELAAAVEALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE78</accession>
    <name>A0A1Q2CE78_9ACTN</name>
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        <submittedName>
            <fullName evidence="5">Signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_05880</name>
        <name evidence="5" type="ORF">SAMN05428934_103124</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05880"/>
    <dbReference type="EnsemblBacteria" id="AQP44401">
        <property type="protein sequence ID" value="AQP44401"/>
        <property type="gene ID" value="RPIT_05880"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68313">
        <property type="protein sequence ID" value="SDY68313"/>
        <property type="gene ID" value="SAMN05428934_103124"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05880"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="3">
        <location>
            <begin position="177"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="154"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY68313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="377" mass="40499" checksum="4993BBF69ADEA9BF" modified="2017-04-12" version="1">MERTKRAWLPEAARIVPIAFFTVVGQLLPLGLEGRYWALVANAVALVLGLVAMRWRRRHPVTLTVALSLLMLPFPSLWLVSGWAYLSLATHLRTRATVLVGLLDVVCFTLGTVVESELPTPSDVAGAVVLSGISVVALGALGSYLGSRRREEAAIQARLELAERQQRLERENAKAEERNRIAREMHDVLAHKITLISLHAGALAYRDDLAPDEVRQAGETIRASAHDALAELRMILGQLRQTDGGAPAKPQPTLADLPALVEGHREAGHQVVLDDRLEAEPLQTVSRHAYRIAQEALTNAARHAPGTPVEIVIAGGPEMGLSLRISNPLSLVAATSPGAGLGLVGLEERVDLAGGHMTAGEVDGHFVVDAWLAWAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEA3</accession>
    <name>A0A1Q2CEA3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytidylate kinase</fullName>
            <shortName evidence="8">CK</shortName>
            <ecNumber evidence="8">2.7.4.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cytidine monophosphate kinase</fullName>
            <shortName evidence="8">CMP kinase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cmk</name>
        <name evidence="10" type="ORF">RPIT_06095</name>
        <name evidence="11" type="ORF">SAMN05428934_103164</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + CMP = ADP + CDP</text>
            <dbReference type="Rhea" id="RHEA:11600"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58069"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>ATP + dCMP = ADP + dCDP</text>
            <dbReference type="Rhea" id="RHEA:25094"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57566"/>
            <dbReference type="ChEBI" id="CHEBI:58593"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the cytidylate kinase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.25" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY69296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06095"/>
    <dbReference type="EnsemblBacteria" id="AQP44436">
        <property type="protein sequence ID" value="AQP44436"/>
        <property type="gene ID" value="RPIT_06095"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY69296">
        <property type="protein sequence ID" value="SDY69296"/>
        <property type="gene ID" value="SAMN05428934_103164"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06095"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004127">
        <property type="term" value="F:cytidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006220">
        <property type="term" value="P:pyrimidine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02020">
        <property type="entry name" value="CMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00238">
        <property type="entry name" value="Cytidyl_kinase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003136">
        <property type="entry name" value="Cytidylate_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011994">
        <property type="entry name" value="Cytidylate_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02224">
        <property type="entry name" value="Cytidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00017">
        <property type="entry name" value="cmk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidylate_kin" evidence="9">
        <location>
            <begin position="3"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="7"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY69296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="214" mass="22983" checksum="D215EEAB497DE309" modified="2017-04-12" version="1">MLIAIDGPSGSGKSTTAKLLARRLGLGYLDTGALYRAATTEYLRCFPEGASGDEVARLVSDAHLVCDTSPDAPCFSINGTDVTAEIREPRISAAVSTVATNLEVRRLLTAHMRRVIDEHGRRIVVEGRDITTVVAPDADVRVLLVADPEARVARRAAEVAGKANRDEVTDQVLRRDRDDSTVSNFTDAADGVTVIDSTFLSPDEVVDRIIALLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEF7</accession>
    <name>A0A1Q2CEF7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase</fullName>
            <shortName evidence="3">GMPMT</shortName>
            <ecNumber evidence="3">2.4.99.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">(1-&gt;4)-alpha-D-glucan:maltose-1-phosphate alpha-D-maltosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">glgE</name>
        <name evidence="6" type="ORF">RPIT_06550</name>
        <name evidence="7" type="ORF">SAMN05428934_103255</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1-&gt;4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + alpha-maltose 1-phosphate = [(1-&gt;4)-alpha-D-glucosyl](n+2) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:42692"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:10183"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:63576"/>
            <dbReference type="EC" id="2.4.99.16"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2 3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.16" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06550"/>
    <dbReference type="EnsemblBacteria" id="AQP44512">
        <property type="protein sequence ID" value="AQP44512"/>
        <property type="gene ID" value="RPIT_06550"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71742">
        <property type="protein sequence ID" value="SDY71742"/>
        <property type="gene ID" value="SAMN05428934_103255"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06550"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030979">
        <property type="term" value="P:alpha-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02124">
        <property type="entry name" value="GlgE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026585">
        <property type="entry name" value="GlgE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021828">
        <property type="entry name" value="GlgE_dom_N/S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357:SF203">
        <property type="entry name" value="PTHR10357:SF203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11896">
        <property type="entry name" value="DUF3416"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aamy" evidence="5">
        <location>
            <begin position="216"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="273"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Maltose 1-phosphate binding" evidence="3">
        <location>
            <begin position="543"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="403"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="432"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>alpha-maltose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:63576"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>alpha-maltose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:63576"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="368"/>
        </location>
        <ligand>
            <name>alpha-maltose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:63576"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="404"/>
        </location>
        <ligand>
            <name>alpha-maltose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:63576"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="3">
        <location>
            <position position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY71742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="668" mass="75241" checksum="F4B218504D4F7876" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEI9</accession>
    <name>A0A1Q2CEI9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glutamate synthase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Glutamate synthase (NADH) small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">gltD</name>
        <name evidence="6" type="ORF">RPIT_06415</name>
        <name evidence="7" type="ORF">SAMN05428934_103228</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06415"/>
    <dbReference type="EnsemblBacteria" id="AQP44490">
        <property type="protein sequence ID" value="AQP44490"/>
        <property type="gene ID" value="RPIT_06415"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71001">
        <property type="protein sequence ID" value="SDY71001"/>
        <property type="gene ID" value="SAMN05428934_103228"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06415"/>
    <dbReference type="UniPathway" id="UPA00946"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006005">
        <property type="entry name" value="Glut_synth_ssu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01317">
        <property type="entry name" value="GOGAT_sm_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="41"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY71001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="488" mass="52634" checksum="02C34DA7F7E8ED42" modified="2017-04-12" version="1">MADPTAFITTPREVAARRPVEERVGDWREVYPGTPGRALLPIISRQAGRCMDCGIPFCHNGCPLGNLIPEWNELVWREEWQPALERLHATNNFPEFTGRLCPAPCETACVVGINRDPVTIKNVEVAIIDKAWDDSRVTPQQPEWHTAKTVAVVGSGPAGLAAAQQLTRAGHTVVVYERADAVGGLLRYGIPEFKMEKSVLNRRLKQMVLEGTQFKTGVEIGVDVTGEDLLDSYEAVVLAIGATVPRDLPVPGRELRGIHQAMEFLPQANRAALGESVDGQITAEGKDVVIIGGGDTGADCLGTSIRQGARSITQLEIMGMPPESRPVNQPWPTYPMTFKVTSAHEEGGDRIYAVSTNRFVGDDDGRVAGLDIVEVRFDGGRFEPVAGTERHIPAQLVLLAMGFTGPQQAGLVDELGLELDPRGNIKRDESFATSVPGVFACGDAGRGQSLIVWAIAEGRSCAQGVDAFLSGTSKLPRPIGPELRQLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEJ5</accession>
    <name>A0A1Q2CEJ5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Holliday junction ATP-dependent DNA helicase RuvA</fullName>
            <ecNumber evidence="8">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ruvA</name>
        <name evidence="10" type="ORF">RPIT_06325</name>
        <name evidence="11" type="ORF">SAMN05428934_103210</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Forms a complex with RuvB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the RuvA family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06325"/>
    <dbReference type="EnsemblBacteria" id="AQP44475">
        <property type="protein sequence ID" value="AQP44475"/>
        <property type="gene ID" value="RPIT_06325"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70524">
        <property type="protein sequence ID" value="SDY70524"/>
        <property type="gene ID" value="SAMN05428934_103210"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06325"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA_helic_RuvA"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
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        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
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        <property type="entry name" value="RuvA"/>
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        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="RuvA_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07499">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01330">
        <property type="entry name" value="RuvA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="SSF46929"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 8 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
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    <feature type="domain" description="HhH1" evidence="9">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="9">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY70524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="203" mass="21248" checksum="191B3AB37EAF5B07" modified="2017-04-12" version="1">MIAQLSGTIATAGATSCVVDVGGVGYLVHVTPATASGLRVGERTVLHTSLVVREDSMTLYGFADENERHAFEIAQGASGVGPKLALAIVSVLGSGDFRRAVQSEDLKRLTSVPGVGLKGAQKMVIELREKVLVLEDSAGGDREAPERADDAWRAQVSEGLQGLGWSVRDADAACDNVAHLVEEDPSIGMGTLLRAALNSLARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEN1</accession>
    <name>A0A1Q2CEN1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase B (Cyclophilin B)</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Peptidylprolyl isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_06645</name>
        <name evidence="4" type="ORF">SAMN05428934_110118</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ10378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06645"/>
    <dbReference type="EnsemblBacteria" id="AQP44530">
        <property type="protein sequence ID" value="AQP44530"/>
        <property type="gene ID" value="RPIT_06645"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ10378">
        <property type="protein sequence ID" value="SDZ10378"/>
        <property type="gene ID" value="SAMN05428934_110118"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06645"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
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        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
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        <property type="entry name" value="PTHR45625"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544446" evidence="1">
        <location>
            <begin position="29"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="2">
        <location>
            <begin position="73"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ10378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="219" mass="22682" checksum="256916DE6BF1C4B5" modified="2017-04-12" version="1">MQIRPIILATLASALTLTACGDANQSNRDPVAVGDTVTCEYPEDGAPARPVDPPPTDNVPATGEVAVTLQLTAGDINIQMDRAKAPCTVNSFVSLAEQGYFDDTDCHRLTDMGIFVLQCGDPTATGTGGPGYTIRDEVSSDLTYPAGTVAMAKRQPPNTGGSQFFLVWADTDLPPEYTVFGTMDQAGIDVVGGIAAQGVDGTDGVSPNAEARITSVTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEP8</accession>
    <name>A0A1Q2CEP8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thiosulfate sulfurtransferase</fullName>
            <ecNumber evidence="2">2.8.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_07010</name>
        <name evidence="6" type="ORF">SAMN05428934_11043</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>hydrogen cyanide + thiosulfate = 2 H(+) + sulfite + thiocyanate</text>
            <dbReference type="Rhea" id="RHEA:16881"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:18022"/>
            <dbReference type="ChEBI" id="CHEBI:18407"/>
            <dbReference type="ChEBI" id="CHEBI:33542"/>
            <dbReference type="EC" id="2.8.1.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.8.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07010"/>
    <dbReference type="EnsemblBacteria" id="AQP44594">
        <property type="protein sequence ID" value="AQP44594"/>
        <property type="gene ID" value="RPIT_07010"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08900">
        <property type="protein sequence ID" value="SDZ08900"/>
        <property type="gene ID" value="SAMN05428934_11043"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07010"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001307">
        <property type="entry name" value="Thiosulphate_STrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045078">
        <property type="entry name" value="TST/MPST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11364">
        <property type="entry name" value="PTHR11364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00380">
        <property type="entry name" value="RHODANESE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="4">
        <location>
            <begin position="13"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="4">
        <location>
            <begin position="153"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDZ08900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="265" mass="27893" checksum="A6BC12A9ED36B683" modified="2017-04-12" version="1">MIPPVVDVSWLADRPDAIVADVRHYLDGRSGAAAYDAGHIPGAVFVPLDDVLADPPDPARGRHPLPATERFAAGLSAVGIDNSSTVVAYDDAGGAMAARLVWLLRLQGVDAALLDGGLAAWPGELSTAAPAPRPASFVARDWPTEALASIDEAATGHAVIDARAAERFRGETEAIDPRAGHIPGARNFPYVGNLRPDGRFRTPEELRERFEALGPAEDVIAYCGSGVTACHNLIALELAGLGRGRLYPGSWSHYSHTDRPAATGE</sequence>
</entry>
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            <end position="50"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="111" mass="11406" checksum="C705D43DA76237D2" modified="2017-04-12" version="1">MAITSAVRFEIVEKGARRVVTAAPPARPDLHLPEAHPARPVAPGRSQRAASCAVERPSARPSAWLAVKVAAVAALAILGTAVSGQSLVLAEPNPAAEYVAGHPAWVHVTAP</sequence>
</entry>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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                <person name="Schumann P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="96" mass="10222" checksum="6B80D8E54FF5256B" modified="2017-04-12" version="1">MCNHEHGHQHGNQQEGGCCGGHTAHGQGGGHHCQHDVVAGPGDELVACVVRGTSTLKSTAETAGLFRDVEGERYYFCCRRCQDLFDAERLASSPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEV2</accession>
    <name>A0A1Q2CEV2_9ACTN</name>
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        </submittedName>
    </protein>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <dbReference type="EnsemblBacteria" id="AQP44631">
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    </dbReference>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="Cyt_c_assmbl_TM_dom"/>
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        <property type="match status" value="1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2" key="3">
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            </authorList>
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        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="SAMN05428934_1217"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07630"/>
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        <property type="component" value="Chromosome"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        <source>
            <dbReference type="EMBL" id="AQP44692.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ22704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
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            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="324" mass="35402" checksum="567276512386F4E1" modified="2017-04-12" version="1">MALQEVSLDDPLSGLRASNLLIETEVGRAIVRRTRRKSLHKLVAHLPDGRRTTLTGVPEERSLRQAAASLTGARPLRAFLLPPGGEVVAKLRPVSTALHYLPWVAGVGLLWAALTNPGLGTLRVVFLALGITIVIIARDAFAKSRRYRDWAFVSKAATTKAIDYVLPGLPEEIEVDDVKVEYGRLLSDIVYRIECPALFDPHEPTSKEFTLALLQWDNNDGVAGQDERRELARRVRATFAAARANAERIGMDHLPAEARDRAGTALKAARLATDEAAPEPERQAALGRAVEILDQLALYYLPTGAQARRAITGSAPPQLPGRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF20</accession>
    <name>A0A1Q2CF20_9ACTN</name>
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        <submittedName>
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        <name evidence="2" type="ORF">RPIT_07760</name>
        <name evidence="3" type="ORF">SAMN05428934_11817</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
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    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="SAMN05428934_11817"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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            <end position="97"/>
        </location>
    </feature>
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            <begin position="66"/>
            <end position="83"/>
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    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
            <dbReference type="EMBL" id="AQP44714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ21525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="97" mass="10921" checksum="5303EDA651E39E4A" modified="2017-04-12" version="1">MNDVILQDAFDVARRHLADAVQPVHRHEIVIASCTEYPTAWVFGYNTRASLTGDFTAGPSSSNSRRRLDPRGRMGRMSRRRPEPRSTTCSTSSRTRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF59</accession>
    <name>A0A1Q2CF59_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Restriction endonuclease subunit M</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07590</name>
        <name evidence="3" type="ORF">SAMN05428934_1222</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP44685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="SAMN05428934_1222"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
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    </dbReference>
    <dbReference type="GO" id="GO:0004519">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1104"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1113"/>
            <end position="1131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ23056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="1541" mass="172129" checksum="6C7408A8AB77811E" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF80</accession>
    <name>A0A1Q2CF80_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
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        <name evidence="4" type="ORF">RPIT_07705</name>
        <name evidence="5" type="ORF">SAMN05428934_1185</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000018">
        <property type="protein sequence ID" value="SDZ21320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44705">
        <property type="protein sequence ID" value="AQP44705"/>
        <property type="gene ID" value="RPIT_07705"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ21320">
        <property type="protein sequence ID" value="SDZ21320"/>
        <property type="gene ID" value="SAMN05428934_1185"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07705"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
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        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="20"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ21320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="208" mass="22075" checksum="F5229C7962384FCB" modified="2017-04-12" version="1">MAASTAAQNPRKQPQQRRSRATVDKILAAAAQVLAEEGDGATTDRIAARAGVSIGSLYQYFPNKGALMLELARRHMAAAGEVLDHVLRLGRPRSVWLPEAVAAVAALHEDGDLHRVLYDHAASTPALAEAFEQTNEALRSRVEELLRAETDLADPGTTAQVLVALVESLTHRLVGTTDADTLAREVTRAANAYLNAACASPRPVGASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF99</accession>
    <name>A0A1Q2CF99_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glucanase</fullName>
            <ecNumber evidence="7">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_07825</name>
        <name evidence="9" type="ORF">SAMN05428934_1135</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the glycosyl hydrolase family 6.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07825"/>
    <dbReference type="EnsemblBacteria" id="AQP44725">
        <property type="protein sequence ID" value="AQP44725"/>
        <property type="gene ID" value="RPIT_07825"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16083">
        <property type="protein sequence ID" value="SDZ16083"/>
        <property type="gene ID" value="SAMN05428934_1135"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07825"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.40">
        <property type="match status" value="1"/>
    </dbReference>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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</entry>
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY98709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="180" mass="19049" checksum="88475AEAECC07D96" modified="2017-04-12" version="1">MKKLSIIVSSTRPTRIAPAVTAWAAELLGADWEVTVLDLAEIGLPFLDEDQMAGTGIYEKPHTLRWKSAIDSSDALAFVNAEYNGFPPAPVLNAIDFLFAEWHGKPAAIVGYGFGGGQRSAAALTTKLTNVKADVVGTVGLVFGEDLTTEGELTVTDERTAELGNLSRRLAEALESSAAA</sequence>
</entry>
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    <protein>
        <submittedName>
            <fullName evidence="2">Phytoene dehydrogenase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_09195</name>
        <name evidence="2" type="ORF">SAMN05428934_107151</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY99282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09195"/>
    <dbReference type="EnsemblBacteria" id="AQP44938">
        <property type="protein sequence ID" value="AQP44938"/>
        <property type="gene ID" value="RPIT_09195"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY99282">
        <property type="protein sequence ID" value="SDY99282"/>
        <property type="gene ID" value="SAMN05428934_107151"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09195"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY99282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="534" mass="56372" checksum="122B3F5379D64797" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFQ2</accession>
    <name>A0A1Q2CFQ2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Glutaminase</fullName>
            <ecNumber evidence="3 5">3.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">glsA</name>
        <name evidence="6" type="ORF">RPIT_08880</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glutaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.2" evidence="3 5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08880"/>
    <dbReference type="EnsemblBacteria" id="AQP44890">
        <property type="protein sequence ID" value="AQP44890"/>
        <property type="gene ID" value="RPIT_08880"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08880"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00313">
        <property type="entry name" value="Glutaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015868">
        <property type="entry name" value="Glutaminase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12544">
        <property type="entry name" value="PTHR12544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04960">
        <property type="entry name" value="Glutaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03814">
        <property type="entry name" value="Gln_ase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="339" mass="36098" checksum="301F6CF0D53E8C67" modified="2017-04-12" version="1">MGPPAALRAGQFRLYAASMPLPLHSFLASQTDRLREVRRGEPMAEPPSMSSGDPERCAVAVANCEGDVVSAGDVGDEFTIQSISKAIAYAYVLEELGHEKVHEFVDVEPSGEAYHVISVEDSSGRPDNPMINAGALVVHSLLPGGDQDERSALVLDLFSRLAGRQLSVDETVFEEELRAGHRNLAIAHLLRAENDLPDDPHDVVAGYTRQCAIRVTAVDLAMMGATLANCGTQPVTGEQIFSPDVVRQTLSVMLTCGMYDDAGDWVSGVGIPAKSGVAGGILAVAPGSLGVAAWSPRLDGHGTSVRGRELVRQVAMKLGLHLLDGRPEPEVDWEASEMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFS9</accession>
    <name>A0A1Q2CFS9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_09365</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44968">
        <property type="protein sequence ID" value="AQP44968"/>
        <property type="gene ID" value="RPIT_09365"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09365"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="61" mass="6218" checksum="48D0A224C814A2EF" modified="2017-04-12" version="1">MAFVLPDRSAVIVTPEGEIVEAPAAHADARQVGAVSVGQHPIGLWETGSVSTLSSFGASGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFT0</accession>
    <name>A0A1Q2CFT0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_09370</name>
        <name evidence="2" type="ORF">SAMN05428934_102435</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="protein sequence ID" value="SDY60697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44969">
        <property type="protein sequence ID" value="AQP44969"/>
        <property type="gene ID" value="RPIT_09370"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY60697">
        <property type="protein sequence ID" value="SDY60697"/>
        <property type="gene ID" value="SAMN05428934_102435"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09370"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY60697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="80" mass="8520" checksum="402FEC73F89EEDE9" modified="2017-04-12" version="1">MTAQRVITLNDASVVAYDAQGAEAWSTDWKPLAEEDRAVGTPPALRQVSPQAVAVIDTGKVEGEGLPTGTYAAQFTHQHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFV6</accession>
    <name>A0A1Q2CFV6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Nicotinate phosphoribosyltransferase</fullName>
            <ecNumber evidence="4 8">6.3.4.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_09520</name>
        <name evidence="11" type="ORF">SAMN05428934_102402</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + nicotinate = ADP + diphosphate + nicotinate beta-D-ribonucleotide + phosphate</text>
            <dbReference type="Rhea" id="RHEA:36163"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32544"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1.</text>
    </comment>
    <comment type="PTM">
        <text evidence="8">Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the NAPRTase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.21" evidence="4 8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY59817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09520"/>
    <dbReference type="EnsemblBacteria" id="AQP44994">
        <property type="protein sequence ID" value="AQP44994"/>
        <property type="gene ID" value="RPIT_09520"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59817">
        <property type="protein sequence ID" value="SDY59817"/>
        <property type="gene ID" value="SAMN05428934_102402"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09520"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00457"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004516">
        <property type="term" value="F:nicotinate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040727">
        <property type="entry name" value="NAPRTase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007229">
        <property type="entry name" value="Nic_PRibTrfase-Fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006405">
        <property type="entry name" value="Nic_PRibTrfase_pncB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11098">
        <property type="entry name" value="PTHR11098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17767">
        <property type="entry name" value="NAPRTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000484">
        <property type="entry name" value="NAPRT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01513">
        <property type="entry name" value="NAPRTase_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7 8" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NAPRTase_N" evidence="9">
        <location>
            <begin position="5"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY59817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="450" mass="48665" checksum="AB4397697557EFFA" modified="2017-04-12" version="1">MTTALLTDHYELTMVQAAMNAGTANRRSLFDLFTRRLPSGRRYGVAAGLGRAIDAIENFRFGDEELSYLHERGIIQDNLAEWLANYHFSGDIWGYPEGEVYFPGSPVLSVEGTFAECCILETVLLSIYNHDSAIAAAASRMTAMAGDRDCVEMGSRRTQEWSAVAAARAAYVAGFASSSNLEAGRTYGIPTIGTAAHSFTLLFDTEEDAFRAQIDTLGEGTALLVDTYDVESAIRLGVELTDGRLGSIRLDSGDLAIMARQARDLLDDLGATQTKIIVTSDLDEWQIAMLQGAPVDGYGVGTSLVTGSGHPTCGFVYKLVARCDSDNPDGELKPVGKKSKGKNTLGGRKFAMRRRGEDGRAETEVIGLGTPPVNDGNDRDLLVPVFKKGELVYHATLEDARQRHRDSLAELPLAARRISNGDPSLETLILDEEGAETTNPYQAAPVVKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFV8</accession>
    <name>A0A1Q2CFV8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenosylhomocysteinase</fullName>
            <ecNumber evidence="4">3.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">S-adenosyl-L-homocysteine hydrolase</fullName>
            <shortName evidence="4">AdoHcyase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ahcY</name>
        <name evidence="9" type="ORF">RPIT_09555</name>
        <name evidence="10" type="ORF">SAMN05428934_102395</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>H2O + S-adenosyl-L-homocysteine = adenosine + L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="3.3.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 6">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="4 6">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 6">Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the adenosylhomocysteinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.3.1.1" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY59630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09555"/>
    <dbReference type="EnsemblBacteria" id="AQP45001">
        <property type="protein sequence ID" value="AQP45001"/>
        <property type="gene ID" value="RPIT_09555"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59630">
        <property type="protein sequence ID" value="SDY59630"/>
        <property type="gene ID" value="SAMN05428934_102395"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09555"/>
    <dbReference type="UniPathway" id="UPA00314">
        <property type="reaction ID" value="UER00076"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004013">
        <property type="term" value="F:adenosylhomocysteinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00401">
        <property type="entry name" value="SAHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00563">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042172">
        <property type="entry name" value="Adenosylhomocyst_ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000043">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015878">
        <property type="entry name" value="Ado_hCys_hydrolase_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020082">
        <property type="entry name" value="S-Ado-L-homoCys_hydrolase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420">
        <property type="entry name" value="PTHR23420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05221">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00670">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001109">
        <property type="entry name" value="Ad_hcy_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00996">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00997">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00936">
        <property type="entry name" value="ahcY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00738">
        <property type="entry name" value="ADOHCYASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00739">
        <property type="entry name" value="ADOHCYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4 6" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AdoHcyase_NAD" evidence="8">
        <location>
            <begin position="223"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="189"/>
            <end position="191"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="252"/>
            <end position="257"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="331"/>
            <end position="333"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="379"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY59630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="465" mass="50728" checksum="911210AF6A940CB3" modified="2017-04-12" version="1">MDYRVADITLTDFGRREITLAEHEMPGLMAMRERFGDSQPLKGARIAGSLHMTVQTAVLIETLVALGAEVRWASCNIFSTQDHAAAAIAAAGIPVFAWKGETLEEYWWCTRQILDWPDGGQPNMILDDGGDATLLVHQGVAAQRAGEVPADTDDDSHEFRVVKQTLRDAHGVVDWEALAAAVRGVTEETTTGVHRLYEMERDQTLLFPAINVNDSVTKSKFDNKYGCRHSLIDGINRATDVLIGGKVAVVCGYGDVGKGCAESLRGQGARVIVTEVDPICALQAAMDGYQVAALDSVVESADIFVTATGCRDVITADQMARMKHQAIVGNIGHFDNEIDMAGLERRADVDKVEVKPQVHEWRFADGHSVLVLSEGRLLNLGNATGHPSFVMSNSFTNQVLAQIELFTKPDEYPVGVYVLPKHLDEEVARLHLAALGVELTTLTQEQAAYLGVPVEGPFKPDSYRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFW3</accession>
    <name>A0A1Q2CFW3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Deoxyribonuclease NucA/NucB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09255</name>
        <name evidence="3" type="ORF">SAMN05428934_1273</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="1610493.RPIT_09255"/>
    <dbReference type="EnsemblBacteria" id="AQP44950">
        <property type="protein sequence ID" value="AQP44950"/>
        <property type="gene ID" value="RPIT_09255"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ23818">
        <property type="protein sequence ID" value="SDZ23818"/>
        <property type="gene ID" value="SAMN05428934_1273"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09255"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544468" evidence="1">
        <location>
            <begin position="26"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ23818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="456" mass="48680" checksum="E31BC7A8B80E8376" modified="2017-04-12" version="1">MKRWLQLIFVGLIAGAMLSPMSAHADTLDENTLDENYSVPAAEPVAPASLTPPTTETYFTDLDGTTDTTKPTLLPAVEPATSTTSRASAQLPGDCAQVRQLIAEKKVSANTLCWGVEEETPIATRNATIISNCRTMAPNGTSWVAFSRFYACYHAKSTVTFYRPATLSIEGRIPIDFYQAVQLDPQSLSVTTASEAKVGPRQGAHGSIASIKLTTDTCTGCSVVNSATTKSGSSLYTSSATMSVNSPGVNARRIAGTSLKLEITAAVNFPFFLWNKTVFRQSRGVLWDCDTEPIGNLKAPGCVFGGITGTVLFDGRTPENGGPMYTTAIHMSDAMNSGLPGKIGSGKYLTRTNSVTIRDANRNAACPRSLIRPPGGYECDEFPFASTLEGGAANTKEARTFWYCNLSDPQRTGPLGFSRCMTPPGEGSFQGGALNSGYMNQRIRNGDKFAVGWSQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFX0</accession>
    <name>A0A1Q2CFX0_9ACTN</name>
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        <submittedName>
            <fullName evidence="4">Phospho-glucose isomerase C-terminal SIS domain-containing protein</fullName>
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    </protein>
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        <name evidence="3" type="ORF">RPIT_09565</name>
        <name evidence="4" type="ORF">SAMN05428934_102393</name>
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    <organism evidence="3 5">
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
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            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
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            <strain evidence="3 5">RP1T</strain>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 6">RP1</strain>
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        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
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        <text evidence="1">Belongs to the PGI/PMI family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09565"/>
    <dbReference type="EnsemblBacteria" id="AQP45003">
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        <property type="gene ID" value="RPIT_09565"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59580">
        <property type="protein sequence ID" value="SDY59580"/>
        <property type="gene ID" value="SAMN05428934_102393"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:mannose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:carbohydrate derivative metabolic process"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="190"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY59580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="337" mass="35427" checksum="B14DC9770BE437D4" modified="2017-04-12" version="1">MRIFDDARLEDAGLETHQGLRHLAQTGARIRRAALTEPLGHLEQADRPRGILALGSEARLVRAVLEATCPVPFMAWPGPGLPAWVGPLDLTIVLGGYDTPEWVLQCAAEAARRGATLVVAAPDDSTLASVTASSSTTLVPSAEPDPMAAAVAVLAILGEIGLGPQVRPEHVADAADLVAEACAPGRDLSENPGKELALCLADCLPLIWGGTVLAARASRRIAEAIRRASGRPALAADAAELDTLLSSAHRRDPFADPFDGGDEDSPCLVLLDDDKLPDRLRGTARRLADRAESVGARITRISSGEADLGATDVERYVTLLQRGLYGAAYLEIGLTEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG32</accession>
    <name>A0A1Q2CG32_9ACTN</name>
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        <submittedName>
            <fullName evidence="8">Sensor histidine kinase inhibitor, KipI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_09990</name>
        <name evidence="8" type="ORF">SAMN05428934_102308</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY57132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09990"/>
    <dbReference type="EnsemblBacteria" id="AQP45078">
        <property type="protein sequence ID" value="AQP45078"/>
        <property type="gene ID" value="RPIT_09990"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57132">
        <property type="protein sequence ID" value="SDY57132"/>
        <property type="gene ID" value="SAMN05428934_102308"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09990"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="CT_A_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003833">
        <property type="entry name" value="CT_C_D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02626">
        <property type="entry name" value="CT_A_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02682">
        <property type="entry name" value="CT_C_D"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AHS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AHS1" evidence="5">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="AHS2" evidence="6">
        <location>
            <begin position="338"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="201"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="582"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="216"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY57132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="603" mass="61266" checksum="F6186F0AB7D46B8A" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG38</accession>
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        <recommendedName>
            <fullName evidence="2">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09960</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09960"/>
    <dbReference type="EnsemblBacteria" id="AQP45073">
        <property type="protein sequence ID" value="AQP45073"/>
        <property type="gene ID" value="RPIT_09960"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09960"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="845"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="1085"/>
            <end position="1119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="1189" mass="125947" checksum="59BA64ED684105F3" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG88</accession>
    <name>A0A1Q2CG88_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10280</name>
        <name evidence="2" type="ORF">SAMN05428934_102249</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45131">
        <property type="protein sequence ID" value="AQP45131"/>
        <property type="gene ID" value="RPIT_10280"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55553">
        <property type="protein sequence ID" value="SDY55553"/>
        <property type="gene ID" value="SAMN05428934_102249"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10280"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY55553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="74" mass="7621" checksum="575CAB86731F991B" modified="2017-04-12" version="1">MAEIRKFDPGAGDGIQKLVREALGENVRPVNPWEAAQPSGDQVAAEDGTGAGAVSDIVGYDFGVVALPDSPDEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG94</accession>
    <name>A0A1Q2CG94_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nicotinamidase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Nicotinamidase/pyrazinamidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10315</name>
        <name evidence="3" type="ORF">SAMN05428934_102242</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10315"/>
    <dbReference type="EnsemblBacteria" id="AQP45138">
        <property type="protein sequence ID" value="AQP45138"/>
        <property type="gene ID" value="RPIT_10315"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55373">
        <property type="protein sequence ID" value="SDY55373"/>
        <property type="gene ID" value="SAMN05428934_102242"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10315"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
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        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY55373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="194" mass="20645" checksum="7A052BFE13455B42" modified="2017-04-12" version="1">MTEPNAVTRALIVVDVQVDFCEGGALGVEGGNDVARRIADLLGSDHGYSHVVATRDHHIDPGPHFSDEPDYVDRWPPHCVVGTPGQQFHPALLRAPFDAVFDKGSYEAAYSGFEGTIGGEPEGDTLAQWLGRHGVTAVDVCGIATDYCVRATATDAAREGFDTRVLGTLIAAVHPANVPGVVTELAEERVEWVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGK8</accession>
    <name>A0A1Q2CGK8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal RNA small subunit methyltransferase I</fullName>
            <ecNumber evidence="7">2.1.1.198</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">16S rRNA 2'-O-ribose C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">rRNA (cytidine-2'-O-)-methyltransferase RsmI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rsmI</name>
        <name evidence="9" type="ORF">RPIT_10960</name>
        <name evidence="10" type="ORF">SAMN05428934_102111</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(1402) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42924"/>
            <dbReference type="Rhea" id="RHEA-COMP:10285"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.198"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the methyltransferase superfamily. RsmI family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.198" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY51383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10960"/>
    <dbReference type="EnsemblBacteria" id="AQP45251">
        <property type="protein sequence ID" value="AQP45251"/>
        <property type="gene ID" value="RPIT_10960"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY51383">
        <property type="protein sequence ID" value="SDY51383"/>
        <property type="gene ID" value="SAMN05428934_102111"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10960"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070677">
        <property type="term" value="F:rRNA (cytosine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000453">
        <property type="term" value="P:enzyme-directed rRNA 2'-O-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11648">
        <property type="entry name" value="RsmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01877">
        <property type="entry name" value="16SrRNA_methyltr_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008189">
        <property type="entry name" value="rRNA_ssu_MeTfrase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46111">
        <property type="entry name" value="PTHR46111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005917">
        <property type="entry name" value="MTase_YraL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00096">
        <property type="entry name" value="TIGR00096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="8">
        <location>
            <begin position="6"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY51383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="279" mass="29307" checksum="823B46DF05F24529" modified="2017-04-12" version="1">MHCGALILAGTPIGSSTDASTTLRETLSSADVIAAEDTRKFLTLTRRLGVETTAKVVSYFEGNEASRTPELVRAIDEGQRVVLVTDAGMPSVSDPGYRLVVACVEAGLRVTAVPGPSAVLTALAVSGLPVDRFCFEGFLPRKSGERRRRLAALAREERTMVFFEAPHRLADFLTDAAAELGADRRGAVCRELTKPYEEVVRDGLADLAAWAADGVRGEVTVVVEGAPPSSTSPDEALALVRDAIAGGAKLSAAVADVAAVTGANRKQLYAAALADKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGM9</accession>
    <name>A0A1Q2CGM9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dihydroorotate dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Dihydroorotate dehydrogenase (Fumarate)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_11090</name>
        <name evidence="6" type="ORF">SAMN05428934_10286</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY50602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11090"/>
    <dbReference type="EnsemblBacteria" id="AQP45271">
        <property type="protein sequence ID" value="AQP45271"/>
        <property type="gene ID" value="RPIT_11090"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY50602">
        <property type="protein sequence ID" value="SDY50602"/>
        <property type="gene ID" value="SAMN05428934_10286"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11090"/>
    <dbReference type="UniPathway" id="UPA00070"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004152">
        <property type="term" value="F:dihydroorotate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012135">
        <property type="entry name" value="Dihydroorotate_DH_1_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000164">
        <property type="entry name" value="DHO_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHO_dh" evidence="4">
        <location>
            <begin position="4"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY50602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="336" mass="35753" checksum="32395E7972440BEB" modified="2017-04-12" version="1">MTDLTTTYLGLPLRNPVVASAGPLSQTVEGIKTLADGGVGAVVMYSLFEEQLRREAAATAELEELYEDSYAEALSYFPSVPRSDRDASHAYLKLVEESVKSIDVPLIASLNGASMGGWTQTARQLADAGAAAIELNIYFVPGDIHMPGLTVEERHLEILAGVKQSVDVPVAVKLSPYFSSIGNVAVQLDAAGADGLVLFNRFLQPDIDIDRITVESGVSLSNPLEARLPRTWIAVLRGKIAASLAATTGVDTAEDVIKYILAGADVVMTTSALLRRGPAYAKVLVDGLEEWLSARQLTLAKARGLLAVPADSAEAYERAGYVSALEKAKTTYGSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGN3</accession>
    <name>A0A1Q2CGN3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase sigma-70 factor, sigma-E family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_10780</name>
        <name evidence="8" type="ORF">SAMN05428934_102149</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY52545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45220">
        <property type="protein sequence ID" value="AQP45220"/>
        <property type="gene ID" value="RPIT_10780"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY52545">
        <property type="protein sequence ID" value="SDY52545"/>
        <property type="gene ID" value="SAMN05428934_102149"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10780"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="20"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="107"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY52545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="169" mass="19089" checksum="D389362C3F9E1485" modified="2017-04-12" version="1">MEHPVSVETGGFDGFVAARAGELFAAAWLLTNDVHHAEDLVQTALSKTYGRYDSFDNDRHFEAYVRTTMYRTFVSWWRRLAWRSETPSDSPPDLPAPVTDIEPGTDLRRALASLPRMQRTVLVLRYFEDRSTRDVAQLLGIPEGTVTSHVSRGLAALRTSPQLNQEDQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGY1</accession>
    <name>A0A1Q2CGY1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mannose-6-phosphate isomerase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Mannose-6-phosphate isomerase, class I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11695</name>
        <name evidence="3" type="ORF">SAMN05428934_106136</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11695"/>
    <dbReference type="EnsemblBacteria" id="AQP45379">
        <property type="protein sequence ID" value="AQP45379"/>
        <property type="gene ID" value="RPIT_11695"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93663">
        <property type="protein sequence ID" value="SDY93663"/>
        <property type="gene ID" value="SAMN05428934_106136"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11695"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY93663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="596" mass="67433" checksum="AAC25EFBA1700E67" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGY6</accession>
    <name>A0A1Q2CGY6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted ATP-dependent carboligase, ATP-grasp superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_11610</name>
        <name evidence="2" type="ORF">SAMN05428934_106153</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY94023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11610"/>
    <dbReference type="EnsemblBacteria" id="AQP45363">
        <property type="protein sequence ID" value="AQP45363"/>
        <property type="gene ID" value="RPIT_11610"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY94023">
        <property type="protein sequence ID" value="SDY94023"/>
        <property type="gene ID" value="SAMN05428934_106153"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11610"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY94023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="400" mass="43022" checksum="45C3AD7A4D762DF5" modified="2017-04-12" version="1">MKRLRALVLSTERSRGALSAVRSLRQSGWTVGVGTPTAHGMLSASRAVSAAHLVPKPRGQARDFVAATNQAIAAGGYDVLFGGTDDFMAALSAYRGDLDAAVAHPDYPAVRSALDKLELTRLAGEVGLSAPRTHAATDDLRRSWRGAVVVKCRSHWTPGRTKAHRIETKLYPDMDSAWPRIEHIRAAGEEAIVQEAIDGRLSALIGVYRDGRLDARVQQEASAVWPIPSGVSTRAVTVPVDADLARRSEALLERLGWSGLVELQFLTGADGLPRLIDLNGRFFGSMSLTNAARPGVPDLWGRWTLGGPVDPLSDAPPGHRYTWLAGDLRRARVERRGGLARDLLGTLRWASSATDSVLSVRDLPPALQLVTDRFTREDAVDPGAPAEVRHGTRLAPGCAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGZ1</accession>
    <name>A0A1Q2CGZ1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_11335</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11335"/>
    <dbReference type="EnsemblBacteria" id="AQP45315">
        <property type="protein sequence ID" value="AQP45315"/>
        <property type="gene ID" value="RPIT_11335"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11335"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="294"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="331"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="450" mass="48081" checksum="C481EE1A61397C4C" modified="2017-04-12" version="1">MAPQPEGEATGALPEHDPNEPVDRAEVIGSGMRTLAIWSGYFLLVAAATLVIGWVFSKFWEGLLPVVLALLVASVLWPVTAALKRIGVPYALGAAISLLGGIGIFAGLISLIAPGVASQWPDLSSRAVQGVRRLQEWAAGPPLNLRDEQLNEWITQGLDFLQARSGDIASQALSLGGSLGSGVVTMLLTLVLTFFFLKDGHQFLALVRRVVGRRAGFHATELLTRLWLTVSGYIRTQAIVSFVDALFIGLGLLVLGVPLAFPLTVLTFIAGFIPIVGAFTAGALAVLVALVSNGLTTAALVLGLIILVQQIEGNVLQPLLQSKVMQLHPVVVMLAVLLGAAWFNIIGAFLAVPVAAAIAVFLRYLGDLIDLRTGERSSDDIDWATDDGKSVGWEWEKAAVFFRAILRKNRPDNSGDAVLTDAGAGLDEAERATIRSRLRRLARRRNTHDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH14</accession>
    <name>A0A1Q2CH14_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Hydroxymethylpyrimidine kinase /phosphomethylpyrimidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_11845</name>
        <name evidence="9" type="ORF">SAMN05428934_106105</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ATP = 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + ADP</text>
            <dbReference type="Rhea" id="RHEA:19893"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.7"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP = 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23096"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16892"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; thiamine diphosphate biosynthesis; 4-amino-2-methyl-5-diphosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole: step 3/3.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11845"/>
    <dbReference type="EnsemblBacteria" id="AQP45406">
        <property type="protein sequence ID" value="AQP45406"/>
        <property type="gene ID" value="RPIT_11845"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92997">
        <property type="protein sequence ID" value="SDY92997"/>
        <property type="gene ID" value="SAMN05428934_106105"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11845"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00138"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008902">
        <property type="term" value="F:hydroxymethylpyrimidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008972">
        <property type="term" value="F:phosphomethylpyrimidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01169">
        <property type="entry name" value="HMPP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045029">
        <property type="entry name" value="HMP/HMP-P_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004399">
        <property type="entry name" value="HMP/HMP-P_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013749">
        <property type="entry name" value="PM/HMP-P_kinase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20858">
        <property type="entry name" value="PTHR20858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08543">
        <property type="entry name" value="Phos_pyr_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00097">
        <property type="entry name" value="HMP-P_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phos_pyr_kin" evidence="7">
        <location>
            <begin position="13"/>
            <end position="271"/>
        </location>
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</entry>
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</entry>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY80189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="62" mass="6281" checksum="D831C9FAC93FEF1D" modified="2017-04-12" version="1">MNRTSSIALGLVLLAVGVALLVYRTQGGADLGEPMPVVITILAVVALLGAFGTLGKAFKRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHI1</accession>
    <name>A0A1Q2CHI1_9ACTN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12495</name>
        <name evidence="3" type="ORF">SAMN05428934_104187</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP45520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY80213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45520">
        <property type="protein sequence ID" value="AQP45520"/>
        <property type="gene ID" value="RPIT_12495"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY80213">
        <property type="protein sequence ID" value="SDY80213"/>
        <property type="gene ID" value="SAMN05428934_104187"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12495"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY80213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="273" mass="26929" checksum="D0DC70E2453B56FE" modified="2017-04-12" version="1">MNQNPVQVRSHQRFSTVVRAELRRHLSSRRHLVRLALIAAAGLLAGMGALAFVASFDPEGAAATGGSVPTAMETAGGVVAILLGLSALGAAAAETSDGTVLSSLLLVPDRRRLLAARAVAPMVIGEVTALTAAGAVLAGGLAMSGGSRIDLGVVALSLLAIAVAAPLTALLGFLTGTLVRRGAPAMAIAMFALLVLPLAVGAAQLAAPPALGPALGYALQATPGVAVLQSLSVSAANQGPVPVALTGLAVLAGWVAIVAVGASVQFRREGQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHR5</accession>
    <name>A0A1Q2CHR5_9ACTN</name>
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        <submittedName>
            <fullName evidence="6">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
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        <name evidence="5" type="ORF">RPIT_13305</name>
        <name evidence="6" type="ORF">SAMN05428934_10426</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY75706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45666">
        <property type="protein sequence ID" value="AQP45666"/>
        <property type="gene ID" value="RPIT_13305"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY75706">
        <property type="protein sequence ID" value="SDY75706"/>
        <property type="gene ID" value="SAMN05428934_10426"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13305"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY75706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="329" mass="34331" checksum="DFA53081190B162D" modified="2017-04-12" version="1">MKPTIDDVARAAGLSRGTVSRYLNGGKDVSPRASLAVESAIVATGYSANPHARRLRGSRTGAVALLLPASVESLFADPVFAIMAKECSRALRRLNSTMVLLMADDAEEHARARDFVRGGHVDGVLALNVLGDGAALVEELALSVPVAAAAYPGMLGPRVGCVSADDREASERATRLLMDAGCRRIAHIAGPTPAGGRNPRLEGFEAALGEAFDPDLVVQGDYTYGTARVVVEELLARAAVDGIVAANDFSAFAALDALRERGVDVPSQVRVIGMDDLPAASTTSPPLTTMAQDFVALAEALVEMLEAKLSGLDPDPVLLPMHLVVRSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHS6</accession>
    <name>A0A1Q2CHS6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Xylulokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13275</name>
        <name evidence="4" type="ORF">SAMN05428934_10432</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY75876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13275"/>
    <dbReference type="EnsemblBacteria" id="AQP45661">
        <property type="protein sequence ID" value="AQP45661"/>
        <property type="gene ID" value="RPIT_13275"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY75876">
        <property type="protein sequence ID" value="SDY75876"/>
        <property type="gene ID" value="SAMN05428934_10432"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13275"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="1">
        <location>
            <begin position="4"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="2">
        <location>
            <begin position="290"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY75876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="496" mass="51852" checksum="E39EF1E74121D6F6" modified="2017-04-12" version="1">MTLIAGLDFGSSGLKLVVVDLDGTVVARSQAAYPTSHGRSGEVEQDPADWWRAARDALAECGIADRIDAVGLTGQMQDLIVVAGGRELRPALLYSDTRASAQQDRLAAEVGDWERRVENHLDVTNVAAKIAWLADHEPDTLRRAESLLFGAGAYVGYRLGGRAACDLTTASTTSLLDVQARDWLTDGVTAAGARPDQLPRLLGGEADAVIGKVSREAAADLGLREGVPIVLGMGDAGATTDGIVGIEPGDSYLYLGSTGWLAGVTDTPPDEPSPIHSLALPGWRRRLRIGSVQSAGSAAAWALATFLPGRRFDDAEREVADSVGVLDRRPLCLPGIAGERTPVRDGAFRGAFVGASEATGAVDFYLAVLTGVALGLRHAADELGIHQRRIPLVGGAASSPAWRQILADVFDATIVTGVPGEPGPHSAARSAAGALGLAHSLRPLLGEGAAVEETVPSSANYGPLISIHRQVYPALAQTFHNLHRVRVADPSRKATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHU1</accession>
    <name>A0A1Q2CHU1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fic family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_13420</name>
        <name evidence="5" type="ORF">SAMN05428934_1044</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY75078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13420"/>
    <dbReference type="EnsemblBacteria" id="AQP45686">
        <property type="protein sequence ID" value="AQP45686"/>
        <property type="gene ID" value="RPIT_13420"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY75078">
        <property type="protein sequence ID" value="SDY75078"/>
        <property type="gene ID" value="SAMN05428934_1044"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13420"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="PTHR13504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="3">
        <location>
            <begin position="138"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="224"/>
            <end position="231"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY75078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="394" mass="42119" checksum="C5F8A5C3331BDBBC" modified="2017-04-12" version="1">MKNREAWPGVGYIEATWHADDPAASRRQRALNRGAFRFSLPAVIGDLEPRVDPALAGDADQVCADIRAFDAESASWGVPFASVLLRTESASSSQIENLTAGARAVALASLGGRTGANAVMIAANTDAMRAAVELADRISPNTIRAMHERLNGGDDPANAGRFRDQTVWVGGRSPVTATFVAPPHGQVEPAIDDLCSFARRTDLQPMVQAAIAHAQFETIHPFTDGNGRTGRALVSSILRHRGVSPRMTVPISSGLLADTGEYFAALTAYRGGHLAPIVEAFVEASRRAIENANILRSDINDLRGRILATADRRTANLMKVADLCSAEPALTAEMVADLGVPVPSVYRILDRLAENGVIRVEKPIGGVRVWTVPDLLSALDRFAERAGRRTFSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI48</accession>
    <name>A0A1Q2CI48_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase involved in cell wall bisynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14060</name>
        <name evidence="3" type="ORF">SAMN05428934_1178</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000017">
        <property type="protein sequence ID" value="SDZ20832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14060"/>
    <dbReference type="EnsemblBacteria" id="AQP45787">
        <property type="protein sequence ID" value="AQP45787"/>
        <property type="gene ID" value="RPIT_14060"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ20832">
        <property type="protein sequence ID" value="SDZ20832"/>
        <property type="gene ID" value="SAMN05428934_1178"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14060"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039498">
        <property type="entry name" value="NTP_transf_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14907">
        <property type="entry name" value="NTP_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="318"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ20832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="626" mass="68882" checksum="C5DD932966E6C20A" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI60</accession>
    <name>A0A1Q2CI60_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major Facilitator Superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_13905</name>
        <name evidence="8" type="ORF">SAMN05428934_11119</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ11930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45763">
        <property type="protein sequence ID" value="AQP45763"/>
        <property type="gene ID" value="RPIT_13905"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ11930">
        <property type="protein sequence ID" value="SDZ11930"/>
        <property type="gene ID" value="SAMN05428934_11119"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13905"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="82"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ11930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="314" mass="32645" checksum="39169654E495AB26" modified="2017-04-12" version="1">MPSRWSLALFVVSIVLRTPASVGWNLARQAVVAEAVPAAMRGKAMTALGGTMRAGNLVGPLCGALLLWRFPLWSVFAFAVVTALLATVLLFIPALNSRFDAQTQRNKAARSPEELTARVRWGAVTVAGIAITTLAVLRVGQPILIALSGVHLGWTESQISLMVDVGAAVELVLMFPGGYFKDVLGRSPVLIACLLIYGAGFLLAPLWPTTAGFVVAVVVMSVGNGLGAGINMTIGADLSPATGRARFLSIWAMYSQGGALGGPLVISGLLLVASLPVAMTAVGLCAVAGAAWTAGWARFLDLPKGLGRRRRTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI75</accession>
    <name>A0A1Q2CI75_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_14280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14280"/>
    <dbReference type="EnsemblBacteria" id="AQP45828">
        <property type="protein sequence ID" value="AQP45828"/>
        <property type="gene ID" value="RPIT_14280"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14280"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035595">
        <property type="term" value="F:N-acetylglucosaminylinositol deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016137">
        <property type="term" value="P:glycoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017810">
        <property type="entry name" value="Mycothiol_biosynthesis_MshB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="PTHR12993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03445">
        <property type="entry name" value="mycothiol_MshB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="304" mass="33530" checksum="9F21EE513B7FE08E" modified="2017-04-12" version="1">MHVTQQRLLLVHAHPDDESSQSVATMARYLDQGAHVTLVTCTLGELGEIMLPEWSHFSPAELGAHRQVELESALDVVGVTDHLFLGGPGRYHDSGMTSDDTGRAAVPDEMPDNAFWRADLLEAANHLVEVIRSRRPQVAITYDPFGNYGHPDHIQAHRTLMYAVQLASSPSHRPDLGAPWQVSRVLWNTHNTSKWAEAYAIARERGLELWPGVDEDAATERFGPDPSQIVAVVETSPWLEKCRAALGAHRSQVNLEHPFWQFYSIMQELPGAGEAYLLGSGQPFPPGDGPATDVFEGIDFSEAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIC8</accession>
    <name>A0A1Q2CIC8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Aminoglycoside O-phosphotransferase APH(6)-Id</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Streptomycin 6-kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_14605</name>
        <name evidence="2" type="ORF">SAMN05428934_10993</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_000480968.1">
        <property type="nucleotide sequence ID" value="NZ_FNPU01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14605"/>
    <dbReference type="EnsemblBacteria" id="AQP45886">
        <property type="protein sequence ID" value="AQP45886"/>
        <property type="gene ID" value="RPIT_14605"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06374">
        <property type="protein sequence ID" value="SDZ06374"/>
        <property type="gene ID" value="SAMN05428934_10993"/>
    </dbReference>
    <dbReference type="GeneID" id="60604315"/>
    <dbReference type="GeneID" id="66341466"/>
    <dbReference type="KEGG" id="tfl:RPIT_14605"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006748">
        <property type="entry name" value="NH2Glyco/OHUrea_AB-resist_kin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04655">
        <property type="entry name" value="APH_6_hur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ06374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="278" mass="30824" checksum="5DFBCA6FD24BF5EE" modified="2017-04-12" version="1">MFMPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLKPIEDIADELRGADYLVWRNGRGAVRLLGRENNLMLLEYAGERMLSHIVAEHGDYQATEIAAELMAKLYAASEEPLPSALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIADQMMSNASELRGLHGDLHHENIMFSSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDPRRIAQMADAFSRALDVDPRRLLDQAYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQTSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIE5</accession>
    <name>A0A1Q2CIE5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Beta-xylanase</fullName>
            <ecNumber evidence="4">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_14690</name>
        <name evidence="7" type="ORF">SAMN05428934_10980</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 10 (cellulase F) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14690"/>
    <dbReference type="EnsemblBacteria" id="AQP45899">
        <property type="protein sequence ID" value="AQP45899"/>
        <property type="gene ID" value="RPIT_14690"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06120">
        <property type="protein sequence ID" value="SDZ06120"/>
        <property type="gene ID" value="SAMN05428934_10980"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14690"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044846">
        <property type="entry name" value="GH10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001000">
        <property type="entry name" value="GH10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490">
        <property type="entry name" value="PTHR31490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00331">
        <property type="entry name" value="Glyco_hydro_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00134">
        <property type="entry name" value="GLHYDRLASE10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00633">
        <property type="entry name" value="Glyco_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51760">
        <property type="entry name" value="GH10_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0858">Xylan degradation</keyword>
    <feature type="domain" description="GH10" evidence="5">
        <location>
            <begin position="66"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ06120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="410" mass="46263" checksum="74E90A37AA61E105" modified="2017-04-12" version="1">MYPFPQDGPVADPGLRHRRAHTEVVIRDAAGDPMASAEVTVRHVGHEFGFGASAFEFIPLATGALEGDDRELYERVSDLWLEVFNAGTLPFYWGQFEAERGRTATEALTATARWLRDRGVTLKGHPLVWHTLTAPWLDELTVPEVEAAQRERIRREVAEFAGLIDTWDAINEVVIMPHFDKYPNGITRLSRELGRIETVRLAFDEARSANPNATLLINDFDLGFGYDALLEGLLAAGVEIDAVGLQTHMHQGYRGEEETLEIIDRFARYGLPIHFTETTLVSGHLMPEHIVDLNDYVVDSWPSTPDGEERQADELTRHVRTLFSHPSVKSFTYWNAWDRDSWLGAPSGIIHADGTPKPAFEALRRLVTEEWHTPEQTLRTDDQGRIRVEGWRGRYEATAAGRTTQFTLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIG0</accession>
    <name>A0A1Q2CIG0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14315</name>
        <name evidence="3" type="ORF">SAMN05428934_11245</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ15056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45835">
        <property type="protein sequence ID" value="AQP45835"/>
        <property type="gene ID" value="RPIT_14315"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ15056">
        <property type="protein sequence ID" value="SDZ15056"/>
        <property type="gene ID" value="SAMN05428934_11245"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14315"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544519" evidence="1">
        <location>
            <begin position="26"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ15056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="333" mass="36818" checksum="DFDBF197D80C27A3" modified="2017-04-12" version="1">MTLKRRLAAALAAAAMLVWGRVATAAAEEVDMYSNPGGHANNGRLWQTDCEMYSSTVVRCETDIWASVVRYENGRFRTITGWHFNNLTYLPSYRGAWANNPLGVPSDSFTSNGRTWRTECDTAATGSGACRSYIWTNYAAYEGGAYRNKTGWVFNNLVRFAHDQIQPVKTVPPHVLDQVRLDFSGLGPLKAGVSHADLARLGYLTATGHECDAYRETTELRSRGIAVTFGRSDVLVQSRNIFTVDGARPGLSIGSIRGIYGSRFKVEAKENYGRTQYFGSVREGDRELIFRVRGVPDGYGGFEYAPTRTLVDTDVVYEISAGEYTDDVSWGGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIH5</accession>
    <name>A0A1Q2CIH5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyruvate dehydrogenase (Acetyl-transferring) E1 component subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_00350</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00350"/>
    <dbReference type="EnsemblBacteria" id="AQP45938">
        <property type="protein sequence ID" value="AQP45938"/>
        <property type="gene ID" value="RPIT_00350"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00350"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016624">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017596">
        <property type="entry name" value="PdhA/BkdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11516:SF41">
        <property type="entry name" value="PTHR11516:SF41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03181">
        <property type="entry name" value="PDH_E1_alph_x"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="E1_dh" evidence="3">
        <location>
            <begin position="32"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="358" mass="39093" checksum="90F12320B9E63130" modified="2017-04-12" version="1">MVQLLTPDGERLEHDEFAFTGTTDDLVGFLRDMILARRFDAEATALQRHGELGLWTPLLGQEAAQVGSARAVREGDVVFPSYREHAVAMVLGVPLTNLLGLFRGSNGGDWEKLETFKNYQIVIGCQTLHATGYAMGLQFDGAVGNDDDADNSAVIVYHGDGAASQGDVNEAYVFAASYNAPVVFFCQNNQWAISEPIALQSRIPLFQRAQGFGFPGVQVDGNDVLAVKAVTDWAMQRARAGEGPSFIEAFTYRMGAHTTSDDPTKYRRAAEDEAWKGRDPVARLTTYLRNEGAIDDAWLAAIDDEGKALGADARASIPQLEDTTMDKLFATVYAEPTVALEAQRREYAEYAASFEENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CII1</accession>
    <name>A0A1Q2CII1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_14585</name>
        <name evidence="4" type="ORF">SAMN05428934_10997</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45883">
        <property type="protein sequence ID" value="AQP45883"/>
        <property type="gene ID" value="RPIT_14585"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06456">
        <property type="protein sequence ID" value="SDZ06456"/>
        <property type="gene ID" value="SAMN05428934_10997"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14585"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans_2" evidence="2">
        <location>
            <begin position="71"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ06456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="287" mass="31106" checksum="3DD9897E1F571524" modified="2017-04-12" version="1">MSLVWVIVGLVAMAAVLLDMFQTLLYPSGDGWLSAPFMRLIWRASKRLGHPLGSATGPLAMVSSIALWVVLMVTAGALIYVPYVPDGFLYSPGIDPSRYPDFAEALYLSLVSIATLGFGDVVGIGPWLRFAPPLEALAGFAVLTAALTWFSQIEGPLVRRRALAMELRTLAETDAAGHLVDWHPSAAHATLSGLARSILEVRTDFAHHTEQFYFQETEPNMALSLQLDQALALRDAALAAQDVSVRDGGQQLRVALEQFAHLLASEFVDTDGAVASTLDAYRTEHSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIJ5</accession>
    <name>A0A1Q2CIJ5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsR</name>
        <name evidence="6" type="ORF">RPIT_14510</name>
        <name evidence="7" type="ORF">SAMN05428934_109114</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bS18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14510"/>
    <dbReference type="EnsemblBacteria" id="AQP45870">
        <property type="protein sequence ID" value="AQP45870"/>
        <property type="gene ID" value="RPIT_14510"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06776">
        <property type="protein sequence ID" value="SDZ06776"/>
        <property type="gene ID" value="SAMN05428934_109114"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14510"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00270">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001648">
        <property type="entry name" value="Ribosomal_S18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018275">
        <property type="entry name" value="Ribosomal_S18_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036870">
        <property type="entry name" value="Ribosomal_S18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479">
        <property type="entry name" value="PTHR13479"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01084">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00974">
        <property type="entry name" value="RIBOSOMALS18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46911">
        <property type="entry name" value="SSF46911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00165">
        <property type="entry name" value="S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00057">
        <property type="entry name" value="RIBOSOMAL_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ06776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="79" mass="8944" checksum="41626E94DD1D5385" modified="2017-04-12" version="1">MAGPQRKPVNKKKILPVKKTRVSNIDYKDINTLKKFISERGKIRARRVTGLSVQDQRKIALAVKNAREVALLPYASTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIK1</accession>
    <name>A0A1Q2CIK1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Low molecular weight phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_00335</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the low molecular weight phosphotyrosine protein phosphatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00335"/>
    <dbReference type="EnsemblBacteria" id="AQP45937">
        <property type="protein sequence ID" value="AQP45937"/>
        <property type="gene ID" value="RPIT_00335"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00335"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017867">
        <property type="entry name" value="Tyr_phospatase_low_mol_wt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00719">
        <property type="entry name" value="LMWPTPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LMWPc" evidence="3">
        <location>
            <begin position="2"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="156" mass="17190" checksum="E8164B0D8A1AB533" modified="2017-04-12" version="1">MARLVFVCWGNICRSPMAERIARRMIDEQGLDIEVESFGVSEEEAGNPIDRRAARTLIKAGYDPDGHRARKIGAAHIKSADLVVAAEPLHVDRLQRIAPGASNIVLLNDFNPAMDPGTPLIDPWYGDEAGFQETLDDLEAAMEGILRAVQERAARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIM1</accession>
    <name>A0A1Q2CIM1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA topoisomerase 1</fullName>
            <ecNumber evidence="8">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">DNA topoisomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">topA</name>
        <name evidence="11" type="ORF">RPIT_01455</name>
        <name evidence="12" type="ORF">SAMN05428934_10839</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01455"/>
    <dbReference type="EnsemblBacteria" id="AQP45957">
        <property type="protein sequence ID" value="AQP45957"/>
        <property type="gene ID" value="RPIT_01455"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01678">
        <property type="protein sequence ID" value="SDZ01678"/>
        <property type="gene ID" value="SAMN05428934_10839"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01455"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03363">
        <property type="entry name" value="TOPRIM_TopoIA_TopoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00952">
        <property type="entry name" value="Topoisom_1_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005733">
        <property type="entry name" value="TopoI_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028612">
        <property type="entry name" value="Topoisom_1_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025589">
        <property type="entry name" value="Toprim_C_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034149">
        <property type="entry name" value="TOPRIM_TopoI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42785">
        <property type="entry name" value="PTHR42785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13368">
        <property type="entry name" value="Toprim_C_rpt"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="SSF56712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01051">
        <property type="entry name" value="topA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPOISOMERASE_I_PROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="10">
        <location>
            <begin position="4"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with DNA" evidence="8">
        <location>
            <begin position="177"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="802"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="829"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="858"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="8">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="326"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP45957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDZ01678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="884" mass="97162" checksum="89CF3DBF5EEEF24B" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIN3</accession>
    <name>A0A1Q2CIN3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome c oxidase subunit 1</fullName>
            <ecNumber evidence="9">7.1.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_03640</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 9">Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 9">
            <text>4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 = 4 Fe(III)-[cytochrome c] + 4 H(+)(out) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11436"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="7.1.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the heme-copper respiratory oxidase family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.9" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03640"/>
    <dbReference type="EnsemblBacteria" id="AQP45998">
        <property type="protein sequence ID" value="AQP45998"/>
        <property type="gene ID" value="RPIT_03640"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03640"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015990">
        <property type="term" value="P:electron transport coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006119">
        <property type="term" value="P:oxidative phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023616">
        <property type="entry name" value="Cyt_c_oxase-like_su1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036927">
        <property type="entry name" value="Cyt_c_oxase-like_su1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000883">
        <property type="entry name" value="Cyt_C_Oxase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023615">
        <property type="entry name" value="Cyt_c_Oxase_su1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014241">
        <property type="entry name" value="Cyt_c_oxidase_su1_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10422">
        <property type="entry name" value="PTHR10422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00115">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01165">
        <property type="entry name" value="CYCOXIDASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81442">
        <property type="entry name" value="SSF81442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02891">
        <property type="entry name" value="CtaD_CoxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50855">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00077">
        <property type="entry name" value="COX1_CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0186">Copper</keyword>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="78"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="124"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="204"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="250"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="350"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="468"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="COX1" evidence="10">
        <location>
            <begin position="19"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP45998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="570" mass="63580" checksum="99FF096385A12BF3" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIX0</accession>
    <name>A0A1Q2CIX0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07395"/>
    <dbReference type="EnsemblBacteria" id="AQP46076">
        <property type="protein sequence ID" value="AQP46076"/>
        <property type="gene ID" value="RPIT_07395"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07395"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP46076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="205" mass="23214" checksum="B1B66F78A5A6B282" modified="2017-04-12" version="1">MCQAGGVPVLTFDQSLPWRPQRVLVAGTSGSGKTTWASRIAHQLGVGHVEIDALYHGPNWTPRESFVEDVHALVGEEHWVTEWQYSSVRAVLASRADLMVWLDLPVATVMRQVTMRTLRRRLRREVLWNGNREPALWTVATEPDHIVRWAWKTRRRTAERIVALMNERPDLPVVRLTSHREARAWVAGPLAASSPGGMAYQREGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ37</accession>
    <name>A0A1Q2CJ37_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alpha-1,4 glucan phosphorylase</fullName>
            <ecNumber evidence="10">2.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_11875</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + phosphate = [(1-&gt;4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:41732"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9586"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.4.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycogen phosphorylase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.1" evidence="10"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11875"/>
    <dbReference type="EnsemblBacteria" id="AQP46146">
        <property type="protein sequence ID" value="AQP46146"/>
        <property type="gene ID" value="RPIT_11875"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11875"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008184">
        <property type="term" value="F:glycogen phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102250">
        <property type="term" value="F:linear malto-oligosaccharide phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102499">
        <property type="term" value="F:SHG alpha-glucan phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011833">
        <property type="entry name" value="Glycg_phsphrylas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000811">
        <property type="entry name" value="Glyco_trans_35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035090">
        <property type="entry name" value="Pyridoxal_P_attach_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11468">
        <property type="entry name" value="PTHR11468"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00343">
        <property type="entry name" value="Phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000460">
        <property type="entry name" value="Pprylas_GlgP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02093">
        <property type="entry name" value="P_ylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00102">
        <property type="entry name" value="PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 9 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000460-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP46146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="832" mass="93229" checksum="488C1EF54BC1B645" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ40</accession>
    <name>A0A1Q2CJ40_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 12">Dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="6 12">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">RPIT_10965</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 12">
            <text>a dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9517"/>
            <dbReference type="Rhea" id="RHEA-COMP:9527"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>a dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:9517"/>
            <dbReference type="Rhea" id="RHEA-COMP:9527"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the glycosyltransferase 39 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="6 12"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10965"/>
    <dbReference type="EnsemblBacteria" id="AQP46131">
        <property type="protein sequence ID" value="AQP46131"/>
        <property type="gene ID" value="RPIT_10965"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10965"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027005">
        <property type="entry name" value="GlyclTrfase_39-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="Glyco_trans_39/83"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032421">
        <property type="entry name" value="PMT_4TMC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050">
        <property type="entry name" value="PTHR10050"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16192">
        <property type="entry name" value="PMT_4TMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 12 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="366"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="413"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="448"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="PMT" evidence="13">
        <location>
            <begin position="76"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_4TMC" evidence="14">
        <location>
            <begin position="295"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF16192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="AQP46131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="490" mass="54552" checksum="41191DFDF10FC9FE" modified="2017-04-12" version="1">MAFALRVWNVGYPAKILFDETYYAKEAWGILHSGYERKWGEDANAQIAEGDLSGFLDAPSYVVHPPLGKMLIALGEWGFGMTPFGWRISAVVFGTLLVFFTIRLARRLSRSTLVGAMAGLILTFDGLAFVMSRLALLDVFQATFAVAAVSALVADRDWFRHKLADHLRSIGEPDLGGRFGPLLLWRPWRVLAGVLFGASCAVKWNSIFMVAAFGILVVFWDLGARRLAGAGRKQWWSLAIDAPAAFVQLVVVAVPVYIASWFRWLTTDGGYYRQWGVENPDDPVVQRVGAALGALWHYHHEAYNFHTGEKMMQEATHPYEAHPAGWLFMIRPIGIEAVNGIEPGTDGCDAVGTTCLRIISAMGTPLLWWFAAAAIAAAVVWWILGRDWRFGVPLLGIASTYLPWFRYADRPLFFFYAIMIIPFSATVLAMALGKILGPVGHPRRRLRAMAVGIVLALIILNFAFIYPILTADLLTKPAWMLRMWLGNAWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ42</accession>
    <name>A0A1Q2CJ42_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribose ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_11500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11500"/>
    <dbReference type="EnsemblBacteria" id="AQP46139">
        <property type="protein sequence ID" value="AQP46139"/>
        <property type="gene ID" value="RPIT_11500"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11500"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP46139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="319" mass="33667" checksum="19B35027E11C834A" modified="2017-04-12" version="1">MSRILRSSIQQVFVFAALILIYIFFMIFAPNFAQPTIALDIVQQSAYVGVMALGATFVIATGGIDLSVGTGMTFAAVMAGVFLSGDWMNLPLAAGLLLTLLVGAVVGLINGLNISYLGLPPFIATLAMMMVARGLALVISDKSTISIKNSGYIWLASGELIPGVKNAILIFIIMAIIAAVLLNKTLLGRYALAIGSNEEATRLSGVNVKFWKTMVYIAAGVFMALGAILYSARFGFVQPAEGVGFELNVIAAVVIGGTSLSGGRANIIGTVVGALIMETLRKGLQMMGIAQEWQLVVTGIVVLIAVFVDIVRRKRQSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ91</accession>
    <name>A0A1Q2CJ91_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP46189">
        <property type="protein sequence ID" value="AQP46189"/>
        <property type="gene ID" value="RPIT_14365"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14365"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="100" mass="10659" checksum="D979681F4CD605D7" modified="2017-04-12" version="1">MQPYGAPGYGYGYGSAEHPQASTVLLLGVGGFLFMPLWFIAWHLGGRARDEIRGGAPFRWDGNLKIGFLLGKVMGILTILGFVLSVLFMILAGGLMVLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJA8</accession>
    <name>A0A1Q2CJA8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_14865</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14865"/>
    <dbReference type="EnsemblBacteria" id="AQP46197">
        <property type="protein sequence ID" value="AQP46197"/>
        <property type="gene ID" value="RPIT_14865"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14865"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032836">
        <property type="entry name" value="DsrE2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027396">
        <property type="entry name" value="DsrEFH-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13686">
        <property type="entry name" value="DrsE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75169">
        <property type="entry name" value="SSF75169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP46197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="163" mass="18053" checksum="7B8A9672769EACF7" modified="2017-04-12" version="1">MAFICSKGNLDMAYPALIMGNSALGEGIEVHIFFTFWGLDIVHKKTNKNLKFTLSGNTAMHMPQLGRLKPGLEHVSMPQAMGNIPFMTRFATSMMKKQMEELEVPDVPDFIDLLHAAGAHMYACKLTFDMMKMIEADLHPGVEGVISATDFIEISEGAQVIFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJH0</accession>
    <name>A0A1Q2CJH0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mutator family transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_14010</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the transposase mutator family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP46185">
        <property type="protein sequence ID" value="AQP46185"/>
        <property type="gene ID" value="RPIT_14010"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14010"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001207">
        <property type="entry name" value="Transposase_mutator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33217">
        <property type="entry name" value="PTHR33217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00872">
        <property type="entry name" value="Transposase_mut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0814">Transposable element</keyword>
    <keyword evidence="4 6" id="KW-0815">Transposition</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP46185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="421" mass="47004" checksum="D3BAFE8616DA7017" modified="2017-04-12" version="1">MPQEPADLGPDQREAIAHMVRQAKDAGIALTGPDGLLKALTAQIVEAALDEELNEHLGYDKHNPIGRGSGNSRNGTRAKTVLTDTVGAIDIQVPRDRNGTFEPQLVKKRQRRLSDMDAMVLSLFAKGLTTGEIAAHFAEVYGTSVSKDTISRITDRVVDEMTTWMARPLERIYAAIFIDAIVVKVRDGQVRNQPYYAAIGVDLDGHKDILGIWPGNGDGESAKFWFACLTELKNRGVQDVFFIVCDGLKGRPDSIGNVFPQAKVQTCLLHLLRNSFSYASKRHWPEIAVNLKPVYEAATAADAQRAFEEFAEKWGKAYPAMIRLWRSAWAEFVPFLDYDLEIRKVLCSTNAIESLNARFRRAVRARGHFPNEQAALKTLYLTVRSLDPKGTGQTRWGMRWKPALNAFAITFADRMPTTQNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CB83</accession>
    <name>A0A1Q2CB83_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2-oxoglutarate ferredoxin oxidoreductase subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_00030</name>
        <name evidence="6" type="ORF">SAMN05428934_10939</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00030"/>
    <dbReference type="EnsemblBacteria" id="AQP43408">
        <property type="protein sequence ID" value="AQP43408"/>
        <property type="gene ID" value="RPIT_00030"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05347">
        <property type="protein sequence ID" value="SDZ05347"/>
        <property type="gene ID" value="SAMN05428934_10939"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00030"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016903">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022367">
        <property type="entry name" value="2-oxoacid/accept_OxRdtase_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033412">
        <property type="entry name" value="PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17147">
        <property type="entry name" value="PFOR_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03710">
        <property type="entry name" value="OAFO_sf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POR" evidence="2">
        <location>
            <begin position="17"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="POR_N" evidence="3">
        <location>
            <begin position="250"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="PFOR_II" evidence="4">
        <location>
            <begin position="511"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDZ05347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="616" mass="65828" checksum="C0935E860F0E3EBB" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBD7</accession>
    <name>A0A1Q2CBD7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aminoacyl-tRNA hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Ribosome-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_00100</name>
        <name evidence="5" type="ORF">SAMN05428934_10925</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00100"/>
    <dbReference type="EnsemblBacteria" id="AQP43420">
        <property type="protein sequence ID" value="AQP43420"/>
        <property type="gene ID" value="RPIT_00100"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05030">
        <property type="protein sequence ID" value="SDZ05030"/>
        <property type="gene ID" value="SAMN05428934_10925"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00100"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RF_PROK_I" evidence="3">
        <location>
            <begin position="29"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="104"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ05030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="148" mass="16084" checksum="7260AC58FD1D6FB6" modified="2017-04-12" version="1">MSELTVDPGPGIPDGLVIPGGELTERFARASGPGGQGVNTTDSKVQLSFDIATSSVLSDAQRRRALHRLRHRLAGSVLTVESSEQRSQFQNRSAARQRLAAILREALAPPPPKRRATRPTRGSVERRLSSKRKRAETKAARRRPGDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBL6</accession>
    <name>A0A1Q2CBL6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF218 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43504">
        <property type="protein sequence ID" value="AQP43504"/>
        <property type="gene ID" value="RPIT_00625"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00625"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06259">
        <property type="entry name" value="YdcF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003848">
        <property type="entry name" value="DUF218"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02698">
        <property type="entry name" value="DUF218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="DUF218" evidence="2">
        <location>
            <begin position="62"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="231" mass="25073" checksum="6FA8EA0326772537" modified="2017-04-12" version="1">MTDDVGSSSDGARPRRRRLRWVLGLVVALAVAPMLGAAVHVGVGSWGGAYDVEGVPERAVGMVLGAKAGPNGPSDFLAARLEVARRLYRQGKISAILVSGDGRERPSSETAAMRDYLVERGIPDEHIVEDPAGFDTYDSCVRAHEVYGVRELILVTQDYHLGRALTICRAAGMDAVGVGDTSMFGRYPLNWIKGWLREWPANVKMEWDLLTARPPQSDPFDGALLEAVGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBU0</accession>
    <name>A0A1Q2CBU0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01000"/>
    <dbReference type="EnsemblBacteria" id="AQP43572">
        <property type="protein sequence ID" value="AQP43572"/>
        <property type="gene ID" value="RPIT_01000"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01000"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="244"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="465" mass="50468" checksum="E9A8E8D65AECE11E" modified="2017-04-12" version="1">MTDDDLRSFLSAFAKLSDLANRIDAGSGNQQRFTDAVSDRLGTDATRLSVLSEDIPPHRYVDWDVALGQLMAQDPEAVLLGLGGGQERYHRVLGDILADRWANFPVGQVDYVNLPSGPETTHQAIGLGARSFTHRGTPVLVFQRRGGSDGDGAPAVDVMSTDSSVAVALLDELRRLSDEHSVLRGQVVTLGLSDDHRPVYQFLPRTRVPASDVILPPGTLARIGGHVQGIARHADRLRAHGQHLKRGLLLYGPPGTGKTHTVRHLLGELEGHTVVLLRGQALMMISQAAALARAMQPSVVVLEDCDLVAEDRSFDGSTAVLFEVLDAVDGIDGDVDVTFVLTTNRIDVLEEALVQRPGRVDLAVEIPLPDEEGRRGLLKLYSSGIGFSEDALSEAAALSEGMTGSFAKELTRRAVLRAIIDDREPSDEDLLVSLEEQLRDTESLRLHLAHDSVEIEEDLDFFDEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBZ0</accession>
    <name>A0A1Q2CBZ0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01355</name>
        <name evidence="3" type="ORF">SAMN05428934_10818</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01355"/>
    <dbReference type="EnsemblBacteria" id="AQP43628">
        <property type="protein sequence ID" value="AQP43628"/>
        <property type="gene ID" value="RPIT_01355"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01244">
        <property type="protein sequence ID" value="SDZ01244"/>
        <property type="gene ID" value="SAMN05428934_10818"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01355"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="47"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ01244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="301" mass="32179" checksum="8213908B74E71590" modified="2017-04-12" version="1">MLGTIAKGAATAAVAASAGFGWGLVEANLFTVRRLEAPLLPPGGQPLKVLHVSDVHLMADQEAKLSFVSSLAELGPDLVINTGDNISEARSVEVLADAWSDLLRVPGAFVFGSNDYYSPIMRNPLSYLVHGKSTGGGKREPDLPWRELRDRFSEHGWVDLTHRRETLNVNGYRIALRGTDDAHLGRDRYEDVAGPADDAADLNVGVTHAPYLRLLDAMTSDGMDLIFAGHTHGGQVCVPGYGALITNCDLDTRRVKGLSTHTVGSHTAHLHVSAGVGTSPAAPYRFACRPEVTLLTLVPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC81</accession>
    <name>A0A1Q2CC81_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-glucoside transport system substrate-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Sugar ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_01900</name>
        <name evidence="2" type="ORF">SAMN05428934_108128</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ03403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01900"/>
    <dbReference type="EnsemblBacteria" id="AQP43714">
        <property type="protein sequence ID" value="AQP43714"/>
        <property type="gene ID" value="RPIT_01900"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ03403">
        <property type="protein sequence ID" value="SDZ03403"/>
        <property type="gene ID" value="SAMN05428934_108128"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01900"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ03403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="450" mass="49276" checksum="4DAC4E71FBA00516" modified="2017-04-12" version="1">MAKQHWRKARIPALLVAGGLLLSGCLQDPNAGSNQAGGFSLGEPEAGDGIVTIMGAFGGDEEALFNEALQPFIDETGIQVDYVSDQDFTNTIQVRVSAGDLPDIGLFPQPGGVMNLAEGGHIYPIDEFLDYDSLNSTLVPGFLDSARYKGRVYAVPMRMAVKSIVWYPKKAFEENGWNTAPATLQELDELTEQIRTETSTTPWCIAWGSDQATGWVGTDWIEEYVLRMWGPQVYDDWIFGRIPFNDERIVQSIERYGELATPENVIGGNDGIINTPFSDAMNPAFSETPGCYMMRQGNFAIGFFPPEIASNLDEEIGIFVFPRDEEGYDGQPMLGGGDLAAAFSYDADTIAVMEFLSSDQFGGPWAEAGGWLSPHTTFDTSLYPNETTRQIAELAVSSDVFRYDGSDVMPREVGSGSFWTEMVAFQSGKSAQDTADAIAATWPESEEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC82</accession>
    <name>A0A1Q2CC82_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acetyl-CoA C-acetyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Acetyl-CoA acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_01925</name>
        <name evidence="6" type="ORF">SAMN05428934_11619</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000016">
        <property type="protein sequence ID" value="SDZ20471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01925"/>
    <dbReference type="EnsemblBacteria" id="AQP43719">
        <property type="protein sequence ID" value="AQP43719"/>
        <property type="gene ID" value="RPIT_01925"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ20471">
        <property type="protein sequence ID" value="SDZ20471"/>
        <property type="gene ID" value="SAMN05428934_11619"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01925"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="3">
        <location>
            <begin position="7"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="4">
        <location>
            <begin position="300"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="1">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="370"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDZ20471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="414" mass="43420" checksum="789AABD543A38C2C" modified="2017-04-12" version="1">MTTRTAVIVGGNRTPFVKAGGKYAMASAQDLLTAALDGLVARFGLAGQKVDEVVAGAVLKHTRDFNLTREAVLGSALSAHTPACDLQQACGTGLEAVVYVSNKIRLGQMDVGIAGGVDSASDAPIVVSEPMRRAMLDLSRARSLPDKLAALAKIRPADLVPVPPGVVEPRTGLSMGESQARTTAKWEVSREDQDQLALESHHKLAEAWDDGFFDDLVTPYLKVSRDGILRPETSMEALGKLRTVFGKGDEATMTAGNSTALTDGAALVLLAEEEEARRRGWPVWAKVVDAQVAATGYVNGEEDLLLAPVRAIPTLLERNGLTLADFDFYEFHEAFASTVLATLKALEADGHGTVDRTKLNVKGSSLAAGHPFAATGGRIVASLAKMLAEKGPGSRGLVSICAAGGQGVVAILEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCD7</accession>
    <name>A0A1Q2CCD7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MFS transporter, NNP family, nitrate/nitrite transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Nitrate transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_02150</name>
        <name evidence="10" type="ORF">SAMN05428934_10128</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY23138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02150"/>
    <dbReference type="EnsemblBacteria" id="AQP43761">
        <property type="protein sequence ID" value="AQP43761"/>
        <property type="gene ID" value="RPIT_02150"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY23138">
        <property type="protein sequence ID" value="SDY23138"/>
        <property type="gene ID" value="SAMN05428934_10128"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02150"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="PTHR23515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="368"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="402"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="8">
        <location>
            <begin position="19"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP43761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY23138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="446" mass="47818" checksum="7C05A60547D45AB7" modified="2017-04-12" version="1">MAKLIEVAPVHDTGKGAGRVATMSTIAFTLMFAVWLMFGILGVPIQQELGLTDVELSWISALAVLNGSMWRLPAGILADRIGGRRVTLFLVFSTAVAAYFVSRADSYASLLILAFLVGFAGNLFSVGTTWNAAWFSRDRQGLALGVFGAGNVGASVTKFIGPPLIAGTAGATYAFGVEGGWRLVPVIYAALLIVVGVATWLIVPRQDRAPGSAKPIREMLVPLKHVRVWRFSLYYVAVFGAYVALSAWLPKYYVDNFDVGLGTAGLLTATFIFPASLLRPVGGALADRYGARRVMYWTFGLMLATSGILMMPNGYIVITHADGSETQHLAYQLSVWAFAALVFLLGCAMGLGKAAVFKHIPEYFPDNVGSVGGLVGTLGGLGGFILPPLFAYTKVWSGFPTSTFFVIFLLTVVCAVWMHLTIVKMLHDNSPELAGTIELPLEEARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCG3</accession>
    <name>A0A1Q2CCG3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">IS5 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_02285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43787">
        <property type="protein sequence ID" value="AQP43787"/>
        <property type="gene ID" value="RPIT_02285"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02285"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13586">
        <property type="entry name" value="DDE_Tnp_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="2">
        <location>
            <begin position="36"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="133" mass="14848" checksum="BB2B3022DDB03C51" modified="2017-04-12" version="1">MKHEPSHCVGLSPAIGLVLAVKRPGPGRPRTRPEAVLGDKAYSGRGNRTLLRSKRITAVIPQRADEIGHRQRRGSAGGRPPAFDKVTYKNRNVVERSFNDHKQWRGIATRYDKHAAIYRGGVVLRAITLWLHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCJ8</accession>
    <name>A0A1Q2CCJ8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Demethylmenaquinone methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.163</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">menG</name>
        <name evidence="5" type="ORF">RPIT_02595</name>
        <name evidence="6" type="ORF">SAMN05428934_101119</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 2-demethylmenaquinol + S-adenosyl-L-methionine = a menaquinol + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42640"/>
            <dbReference type="Rhea" id="RHEA-COMP:9539"/>
            <dbReference type="Rhea" id="RHEA-COMP:9563"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18151"/>
            <dbReference type="ChEBI" id="CHEBI:55437"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.163"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Quinol/quinone metabolism; menaquinone biosynthesis; menaquinol from 1,4-dihydroxy-2-naphthoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.163" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY25846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02595"/>
    <dbReference type="EnsemblBacteria" id="AQP43842">
        <property type="protein sequence ID" value="AQP43842"/>
        <property type="gene ID" value="RPIT_02595"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY25846">
        <property type="protein sequence ID" value="SDY25846"/>
        <property type="gene ID" value="SAMN05428934_101119"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02595"/>
    <dbReference type="UniPathway" id="UPA00079">
        <property type="reaction ID" value="UER00169"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043770">
        <property type="term" value="F:demethylmenaquinone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102094">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102955">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102027">
        <property type="term" value="F:S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01813">
        <property type="entry name" value="MenG_UbiE_methyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004033">
        <property type="entry name" value="UbiE/COQ5_MeTrFase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023576">
        <property type="entry name" value="UbiE/COQ5_MeTrFase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01209">
        <property type="entry name" value="Ubie_methyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01934">
        <property type="entry name" value="MenG_MenH_UbiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51608">
        <property type="entry name" value="SAM_MT_UBIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01184">
        <property type="entry name" value="UBIE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="1 4 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="4">
        <location>
            <begin position="104"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY25846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="231" mass="25281" checksum="38D57ABE97A0F806" modified="2017-04-12" version="1">MQNQRATMQKRRGDVAAMFDGVAKRYDLFNSVLSLGQVHAWRRATVRAIEPRPGQRILDLAAGTGTSTAAIAESGAYVVASDISIGMLTQGRKQQPHLDFVAGDALALPFPDDTFEAVTISYGLRNVERTLDALVEMRRVTRPGGRLVIAEFSTPTNPAFRHVYTNYLVGALPTIAKASSNPVAYGYLAESIMAWPDQRGLADLMVEAGWTDVEWQNHAGGIVALHRGWKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCP2</accession>
    <name>A0A1Q2CCP2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NADH dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">NADH-quinone oxidoreductase subunit I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_02750</name>
        <name evidence="7" type="ORF">SAMN05428934_101150</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY26754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02750"/>
    <dbReference type="EnsemblBacteria" id="AQP43867">
        <property type="protein sequence ID" value="AQP43867"/>
        <property type="gene ID" value="RPIT_02750"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY26754">
        <property type="protein sequence ID" value="SDY26754"/>
        <property type="gene ID" value="SAMN05428934_101150"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02750"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010226">
        <property type="entry name" value="NADH_quinone_OxRdtase_chainI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10849">
        <property type="entry name" value="PTHR10849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="4"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="52"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY26754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="103" mass="11554" checksum="EF80AAE3A982EA9C" modified="2017-04-12" version="1">MIHGSIRLIEDRCTSCMICARECPTWCIRLTSHQEQTVPAPGARPRTHNVLDTFTIDWSLCMYCGVCIEQCPTDALEWGDSHVPSADSLVDLVHQREQLAPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCQ3</accession>
    <name>A0A1Q2CCQ3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribonuclease VapC</fullName>
            <shortName evidence="5">RNase VapC</shortName>
            <ecNumber evidence="5">3.1.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Toxin VapC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">vapC</name>
        <name evidence="6" type="ORF">RPIT_02975</name>
        <name evidence="7" type="ORF">SAMN05428934_101196</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Toxic component of a toxin-antitoxin (TA) system. An RNase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PINc/VapC protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY28107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02975"/>
    <dbReference type="EnsemblBacteria" id="AQP43903">
        <property type="protein sequence ID" value="AQP43903"/>
        <property type="gene ID" value="RPIT_02975"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY28107">
        <property type="protein sequence ID" value="SDY28107"/>
        <property type="gene ID" value="SAMN05428934_101196"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02975"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00265">
        <property type="entry name" value="VapC_Nob1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022907">
        <property type="entry name" value="VapC_family"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0800">Toxin</keyword>
    <keyword evidence="1 5" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="5"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY28107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="142" mass="15379" checksum="9827639B82A4166F" modified="2017-04-12" version="1">MIALDAPLLVYAHRADSPHHERALATLTTLAAEPVPFAVPWACVNEFLSTVTHPHGYVPPTSPDTALAAVQSLLSLPHVRTLTETADHLRLLSTLIAPGVIGPKMHEARVAAICLGHGITELWTVDRDYSYFPALRTHNPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCX4</accession>
    <name>A0A1Q2CCX4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03340"/>
    <dbReference type="EnsemblBacteria" id="AQP43968">
        <property type="protein sequence ID" value="AQP43968"/>
        <property type="gene ID" value="RPIT_03340"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03340"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="376" mass="38557" checksum="A8394A58E95AE778" modified="2017-04-12" version="1">MGSSTVDVTLTALDDETRAAASDAVLDALTGLGGVRAATSDLAATAPSLEISVRGTDASALGLSVTDAVGLIALNTADFPVGSVAIDGADLSVYIDSGQSVATVEDVENLDLGGLPLSAIADVERVNVAPSISTVNAVRTVTISATPVNSDDVGSVGDEVRAAMEGLDLPDGVTWEIGGVTADVDEAFRQLALAMAAAVLLIYVVLVWLFKSLLQPAILMMSIPFAATGAILALWVTGTPVGLPSLVGMLMLIGIVVTNAIVLIDLVNQYRLRGLDLDEALLRGGQNRVRPIIMTAAATIMAMIPPALGLSGQSSFVSGPMAVAVIGGLVASTLITLIIVPVLYRMIEGWKQRRGFQDPASARAESESPRRAAVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCZ7</accession>
    <name>A0A1Q2CCZ7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">30S ribosomal protein S13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsM</name>
        <name evidence="8" type="ORF">RPIT_03355</name>
        <name evidence="9" type="ORF">SAMN05428934_101271</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03355"/>
    <dbReference type="EnsemblBacteria" id="AQP43971">
        <property type="protein sequence ID" value="AQP43971"/>
        <property type="gene ID" value="RPIT_03355"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30464">
        <property type="protein sequence ID" value="SDY30464"/>
        <property type="gene ID" value="SAMN05428934_101271"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03355"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_S13_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="30s_Rbsml_prot_S13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_S13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019980">
        <property type="entry name" value="Ribosomal_S13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_S13_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF1">
        <property type="entry name" value="PTHR10871:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03631">
        <property type="entry name" value="uS13_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="90"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP43971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY30464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="124" mass="13945" checksum="BFF8A290CCFBBAB3" modified="2017-04-12" version="1">MARLVGVDLPREKRLEVALTYIFGMGKTRAAETLAATGVSGDLRVHQLTDDQLVQLRDHIEGNYEIEGDLRRTVAADIRRKVEIGNYQGRRHRSGLPVRGQRTRTNARTRKGKKKAVAGKKKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD16</accession>
    <name>A0A1Q2CD16_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">Phosphoglucosamine mutase</fullName>
            <ecNumber evidence="6 8">5.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">glmM</name>
        <name evidence="13" type="ORF">RPIT_03455</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23424"/>
            <dbReference type="ChEBI" id="CHEBI:58516"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="EC" id="5.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="6">Activated by phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.10" evidence="6 8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03455"/>
    <dbReference type="EnsemblBacteria" id="AQP43987">
        <property type="protein sequence ID" value="AQP43987"/>
        <property type="gene ID" value="RPIT_03455"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03455"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008966">
        <property type="term" value="F:phosphoglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05802">
        <property type="entry name" value="GlmM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01554_B">
        <property type="entry name" value="GlmM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006352">
        <property type="entry name" value="GlmM_bact"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01455">
        <property type="entry name" value="glmM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="10">
        <location>
            <begin position="3"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="11">
        <location>
            <begin position="159"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="12">
        <location>
            <begin position="260"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="9">
        <location>
            <begin position="391"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="6">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="binding site" description="via phosphate group" evidence="6">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="Phosphoserine" evidence="6">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP43987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="450" mass="46915" checksum="8B58B69F6D92DF96" modified="2017-04-12" version="1">MARLFGTDGVRGVANVDLTAELAVDLAVAAAHILGEAGAFAGHRPLALVGRDPRASGEFLEAAVIAGLASAGVDVVRLGVVPTPAVAYLVSDMNADLGVMISASHNPMPDNGIKFFSRGGVKLDDYLEDAIEARMGEHWERPTGGAVGRITSDLGAVEGYVAHLVSSLGEESNLEGLRVVIDCANGAASLTALEAFAAQGAHIIPIHAEPDGLNINDNCGSTHLGDLIDRVVSEGADLGIALDGDADRCLAVDHEGALVDGDRILAILAIAMKEEHRLHSDTVVATVMSNLGLTNAMREHGIRVDQTKVGDRYVLESMNANGFALGGEQSGHVIISEFANTGDGTLTGLHLASRMVATGKSLKELASVMTVLPQVVINVRNVDKLRAGIDNEVQQAVTAAARRLGDTGRVLLRPSGTEPVVRVMVEAPTTDEAEQIAGELAEMVRVRLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD27</accession>
    <name>A0A1Q2CD27_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">6-phospho-beta-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_03270</name>
        <name evidence="9" type="ORF">SAMN05428934_101255</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="6">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03270"/>
    <dbReference type="EnsemblBacteria" id="AQP43955">
        <property type="protein sequence ID" value="AQP43955"/>
        <property type="gene ID" value="RPIT_03270"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29968">
        <property type="protein sequence ID" value="SDY29968"/>
        <property type="gene ID" value="SAMN05428934_101255"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03270"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001088">
        <property type="entry name" value="Glyco_hydro_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022616">
        <property type="entry name" value="Glyco_hydro_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32092">
        <property type="entry name" value="PTHR32092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02056">
        <property type="entry name" value="Glyco_hydro_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11975">
        <property type="entry name" value="Glyco_hydro_4C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00732">
        <property type="entry name" value="GLHYDRLASE4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="SSF56327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_4C" evidence="7">
        <location>
            <begin position="200"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP43955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY29968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="459" mass="49683" checksum="639FD175A55E9481" modified="2017-04-12" version="1">MKLVITGGGGFRVPLVYDAVATNALAAAGRPAVHIDEVVLHDASAARLEGIARVIRERAAQLDHAPTLKVTTDLRDALTGADFIFAAVRVGGVEGRIADERVALDLGLLGQETIGPGGLAYALRTIPVMRELARVTAEVAPHAWTINFTNPAGIVTQSMREVLGDRVVGICDTPIGLVRRVSRLLGVSLEHDTARVDYDYVGLNHLGWLRSVRIDGVERLPDVLGSDSALDEIEEARVVGKDWVRATGALPNEYLYYYLKTDEAIANIRRSAQTRGQYLQAQQGDFYESVGCCDSPLALWQEALHERESTYMAEAREDSEERRAEDAAGGGYQEVALRLMTALATGSPERMILDVGNLSEGERIIPELPDDVVVEVGCVVDEGGVHPLPVAPLTLSQLGAMSTLRASEEAIAEAARTGDPEKAWEGFSTHPLVRSPRLGKELLDGYSRAHPEIAQLFTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD65</accession>
    <name>A0A1Q2CD65_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_03745</name>
        <name evidence="2" type="ORF">SAMN05428934_101351</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY32822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03745"/>
    <dbReference type="EnsemblBacteria" id="AQP44036">
        <property type="protein sequence ID" value="AQP44036"/>
        <property type="gene ID" value="RPIT_03745"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY32822">
        <property type="protein sequence ID" value="SDY32822"/>
        <property type="gene ID" value="SAMN05428934_101351"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03745"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009351">
        <property type="entry name" value="YcaQ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06224">
        <property type="entry name" value="HTH_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY32822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="400" mass="43930" checksum="086F54E363447B25" modified="2017-04-12" version="1">MPRRLTLAAARRVAVAAQGLAAPRPSRIGPAALGRAIGRMGVLQLDSVNVFERSHYIPLWSRLGPYDKAVLDRLLHHDAGGATLGAYTEYTAHEATVLPVADWPLWAWHRARPERPRYEQWQRENASLLDEVRAEFAERGPARVRDLDHPDNVALGSGWWNKNRVHSAATALFRRGDLVVVGRRRFERVLAPASVLPVEARSDVAEADAVLELIRRAARAYGVATLDDLADYPRLSVSTAKAAVTRLEEAGELEPVVVAGWDRPAWLAAGTTVPRTTAAAAILSPFDPLIWYRPRVERLFGMRYRISIYTPAAQREHGYYVMPVLIDDELVGRVDLKSDRGAGALRVQHAHVEGHAARRAPQLATRLAPLLQEAASWQGLTGVTVSGAGTWAADVGRALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD79</accession>
    <name>A0A1Q2CD79_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Methylenetetrahydrofolate reductase</fullName>
            <ecNumber evidence="8">1.5.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_03830</name>
        <name evidence="10" type="ORF">SAMN05428934_101368</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:19821"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.5.1.20"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19817"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 8">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 8">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.20" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY33290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03830"/>
    <dbReference type="EnsemblBacteria" id="AQP44051">
        <property type="protein sequence ID" value="AQP44051"/>
        <property type="gene ID" value="RPIT_03830"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY33290">
        <property type="protein sequence ID" value="SDY33290"/>
        <property type="gene ID" value="SAMN05428934_101368"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03830"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004489">
        <property type="term" value="F:methylenetetrahydrofolate reductase (NAD(P)H) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006555">
        <property type="term" value="P:methionine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00537">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0274">FAD</keyword>
    <keyword evidence="5 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY33290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="296" mass="31761" checksum="5AC58CDD5A69FF8B" modified="2017-04-12" version="1">MPTPPPTPGSVRELLDAATGPLFSFEFFPPRTDDEEPVLWAAVEALAPLDPDFVSVTYGATGSRRDRTIHATRRIASSGGPLTVGHLTCVAQSKAEIAEALAAYRDVGVTNILAIRGDMPGGGDWVRHPDGLANATELVSFIKEQGDFCVGVAAFANPHETTLDPELDAQILAAKVEAGAEFAITQLFFEAERYAELVARMRAMDCEVPIIPGIMPLTVITQIERFAALSGCPLPERFVGELRALGSKEEVRAHGLAEAVRLCRELLDAGAPGLQFFTQNRSKATREVLAALKGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD87</accession>
    <name>A0A1Q2CD87_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PG_binding_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_03865</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03865"/>
    <dbReference type="EnsemblBacteria" id="AQP44057">
        <property type="protein sequence ID" value="AQP44057"/>
        <property type="gene ID" value="RPIT_03865"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03865"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013156909" description="PG_binding_1 domain-containing protein" evidence="2">
        <location>
            <begin position="40"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="3">
        <location>
            <begin position="132"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="233"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="447" mass="46597" checksum="5A433946F7DB0DA1" modified="2017-04-12" version="1">MRSLVRKRPLLAMTLPAMLMLIIGMLAGQLVRSPDQVAADAAPPAPATLTSRVALGKIQRTESADARLEQTQIALVSPAIPTSAARPIVSALWVDVGDEVTQGDALLDVGGRPTFLMPGRVAAYRALGPGMNGPDVTQLQVGLRSLGYSVEEGETTFGASTKSAVTRFYEDRGYSVVEVGGEELKAAEDAFTAADRAAATAETALRRAKRDYDHAVEAAEALGPAERPTLDGVDDATSAVEFAHEDLEAAREAVNTARAAAGPQIPLGEVAFLVFLPVTVDKISVVVGREVGEGTVQLAAGPLSAIATFPRPVGDAVSIDNHATLIAPDGERWEGVVSNVKLVSETESESDDRVEVTVSLNVPIEIPSGSTMRVNVATFTSPFDQLMVPEAALVTSADGETRVRVEKGQEVRDVVVTVGESGDGMVAVTPVTEGTLAEGDLVVIGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDE5</accession>
    <name>A0A1Q2CDE5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycine dehydrogenase (decarboxylating)</fullName>
            <ecNumber evidence="7">1.4.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glycine cleavage system P-protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glycine decarboxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glycine dehydrogenase (aminomethyl-transferring)</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gcvP</name>
        <name evidence="9" type="ORF">RPIT_04130</name>
        <name evidence="10" type="ORF">SAMN05428934_101430</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(R)-N(6)-lipoyl-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 7">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the GcvP family.</text>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY34994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04130"/>
    <dbReference type="EnsemblBacteria" id="AQP44100">
        <property type="protein sequence ID" value="AQP44100"/>
        <property type="gene ID" value="RPIT_04130"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY34994">
        <property type="protein sequence ID" value="SDY34994"/>
        <property type="gene ID" value="SAMN05428934_101430"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04130"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00613">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00711">
        <property type="entry name" value="GcvP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003437">
        <property type="entry name" value="GcvP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773">
        <property type="entry name" value="PTHR11773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00461">
        <property type="entry name" value="gcvP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7 8">
        <location>
            <position position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR603437-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY34994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="942" mass="101362" checksum="EE09DA05CE1FBCBF" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDF1</accession>
    <name>A0A1Q2CDF1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Beta-ketoacyl-ACP reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_04430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04430"/>
    <dbReference type="EnsemblBacteria" id="AQP44153">
        <property type="protein sequence ID" value="AQP44153"/>
        <property type="gene ID" value="RPIT_04430"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04430"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="239" mass="25237" checksum="AE2C1FA061419E20" modified="2017-04-12" version="1">MLPVTESRVVLVTGGSKGIGRAMAEAFRDAGYRVAATYRSGGVPDGVLGVTCDITDQGQVDQAFETIEKELGPVEVLVANAGVTRDTLLMRMSDDDWQTVIDTNLTGTFRVVRRAARPMMRARFGRIVLISSVVALLGSPGQINYSSSKAALVGMARSLTRELGTRNVTANVVAPGFIETDMTSVLGEDTIADYRKRIPAGRLGSVDDVARAVLFLANDSSGYISGAVLPVDGGLGMGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDQ7</accession>
    <name>A0A1Q2CDQ7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Deoxyribodipyrimidine photo-lyase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Deoxyribodipyrimidine photolyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_04755</name>
        <name evidence="8" type="ORF">SAMN05428934_101560</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DNA photolyase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY38365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04755"/>
    <dbReference type="EnsemblBacteria" id="AQP44210">
        <property type="protein sequence ID" value="AQP44210"/>
        <property type="gene ID" value="RPIT_04755"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY38365">
        <property type="protein sequence ID" value="SDY38365"/>
        <property type="gene ID" value="SAMN05428934_101560"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04755"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901363">
        <property type="term" value="F:heterocyclic compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097159">
        <property type="term" value="F:organic cyclic compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051716">
        <property type="term" value="P:cellular response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018394">
        <property type="entry name" value="DNA_photolyase_1_CS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="PTHR11455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="SSF52425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00394">
        <property type="entry name" value="DNA_PHOTOLYASES_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00691">
        <property type="entry name" value="DNA_PHOTOLYASES_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 5" id="KW-0274">FAD</keyword>
    <keyword evidence="2 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="6">
        <location>
            <begin position="3"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY38365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="467" mass="52743" checksum="34C57B3FB68A72B5" modified="2017-04-12" version="1">MTTSEIVWLRRDLRRHDLPTLAAAAERSGSVAPVFVLDPAFWDTAGAPRRTWLARTLMALRDSYEGRLTLRLGDPQALLPEIAGEFGATSVHISTETEPQGAARDAAAGTALRERGVTLVATGSPYAVTPGRIRRADGEPYQVFTPFSRGWRDHGWRAPAEEPADLRLADDRSDPSAWEVVAQAACCDEVQLPEAGEAAAQERWEWFLDEGLERYGHDRDRPDLDGTSRMSVYLKFGVVHPRTLLADLEARTGTGPERYRLELAWREFYADVLHHHPDSLWQDLRPALTHMRYDEPGAAVEAWRQGRTGFPIVDAAMRQLLGEGWMHNRLRMVVASFLIKHLHTRWQVGADHFLDRLADADLASNQHGWQWVAGTGTDAAPYFRVFNPILQGQKFDPNGDFVRRWVPELRPIDGAAVHEPWRTALARDLDYPTPIIDLKAERAEALERLSEARDARETQPTEHERRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDR8</accession>
    <name>A0A1Q2CDR8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Isoprenyl transferase</fullName>
            <ecNumber evidence="2">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_05050</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05050"/>
    <dbReference type="EnsemblBacteria" id="AQP44259">
        <property type="protein sequence ID" value="AQP44259"/>
        <property type="gene ID" value="RPIT_05050"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05050"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="PTHR10291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="SSF64005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="35"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="79"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="208"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="254" mass="29253" checksum="0BD1367DCE457E91" modified="2017-04-12" version="1">MPEPRRRPTPHPSGASAPDLPRASVPRHVAIVMDGNGRWAKQRGLKRTEGHARGEASLLDVVHGAIELGIPYLSAYAFSTENWKRSPDEVRWLMGFNRDVIHRRRDELNDLGVRIRWAGRRPRLWGSVIRELEVAEEMSKDNDTLTLQFCVNYGGRAEIVDAAREIARLARDGKLDPDRLTEDRFARFLDEPGIPDVDLFLRSSGEQRISNFLLWQSAYAEFIFLDRLWPDFDRRDLWAAVTDYATRERRFGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDS0</accession>
    <name>A0A1Q2CDS0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable queuosine precursor transporter</fullName>
            <shortName evidence="1">Q precursor transporter</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04985</name>
        <name evidence="3" type="ORF">SAMN05428934_101603</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY39472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04985"/>
    <dbReference type="EnsemblBacteria" id="AQP44247">
        <property type="protein sequence ID" value="AQP44247"/>
        <property type="gene ID" value="RPIT_04985"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY39472">
        <property type="protein sequence ID" value="SDY39472"/>
        <property type="gene ID" value="SAMN05428934_101603"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04985"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990397">
        <property type="term" value="P:queuosine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02088">
        <property type="entry name" value="Q_prec_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003744">
        <property type="entry name" value="YhhQ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34300">
        <property type="entry name" value="PTHR34300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02592">
        <property type="entry name" value="Vut_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00697">
        <property type="entry name" value="TIGR00697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY39472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="232" mass="24509" checksum="E67363832D37FCB4" modified="2017-04-12" version="1">MPATPTPSFASRPRGVFDIVVALFCALLLISNVAAVKLIQFGPDVEVLGFPVLPIITDGGAFLFPLTYILGDVLAEVYGLTGARRAILLGFAVSILASVTFLLVGAAPPAADWPNQDAFDAVLGFVPRIVVASLAGYLAGQFLNAWVLVKLKQRSSEGSLWARLMGSTLVGEAADTILFCIIAFAGIITGGTLVNYIIVGYVYKVLVEAAFLPVTYRVIAAVKRREPSYSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDS2</accession>
    <name>A0A1Q2CDS2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase sigma factor, sigma-70 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_05120</name>
        <name evidence="8" type="ORF">SAMN05428934_101630</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY40199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05120"/>
    <dbReference type="EnsemblBacteria" id="AQP44272">
        <property type="protein sequence ID" value="AQP44272"/>
        <property type="gene ID" value="RPIT_05120"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY40199">
        <property type="protein sequence ID" value="SDY40199"/>
        <property type="gene ID" value="SAMN05428934_101630"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05120"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="78"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="6">
        <location>
            <begin position="210"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY40199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="283" mass="30502" checksum="050A4A2C86D321EB" modified="2017-04-12" version="1">MHISSQTLPTVVIGGRDEAIGRAIEAGVYAEHLLATHSSNHDWESLEAVARRGREAAELFWWVGVKMAMQAAGSHAQRTGAPVEELFQDACLAVAEAIRRFDHSRGTRWTTLVHTRIKHALLDASEYRVGLAASSRADRRAAHRASRLADDLAAEGVSVGLARAAEAAGVSAAAVTRAKTRLVSIDDVQEADLSSGVDDVAHAGPGVDFLDLLEPHHRQVLELRFGIGCEPLTLAETARRLRATTSTIHRWEKEAIGAARDVLDRERTTAAPQRGAAAWRVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDU1</accession>
    <name>A0A1Q2CDU1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_05095</name>
        <name evidence="10" type="ORF">SAMN05428934_101625</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16845"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 8">Belongs to the citrate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY40052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05095"/>
    <dbReference type="EnsemblBacteria" id="AQP44267">
        <property type="protein sequence ID" value="AQP44267"/>
        <property type="gene ID" value="RPIT_05095"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY40052">
        <property type="protein sequence ID" value="SDY40052"/>
        <property type="gene ID" value="SAMN05428934_101625"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05095"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00717"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004108">
        <property type="term" value="F:citrate (Si)-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06114">
        <property type="entry name" value="EcCS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024176">
        <property type="entry name" value="Citrate_synthase_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010953">
        <property type="entry name" value="Citrate_synthase_typ-I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001369">
        <property type="entry name" value="Citrate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="SSF48256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01798">
        <property type="entry name" value="cit_synth_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001369-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY40052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="428" mass="47693" checksum="01B88D8DB731B3A0" modified="2017-04-12" version="1">MGDTATVTIDGVSYDLPVVTGTEGERALDISKLRSTTGLITLDDGYANTGSCQSAITFIDGEAGILRYRGIPIEDLAERSSFVETAQLLIFGRLPNEAQRSEFRTLLTENAALHRDMRKHFDGFPVTAHPMAILSAMVNAIQTHEVRDEEATDRQHFKQAAAGLMAKTRTIAAASYKSHIGQPIAYPRYDLNYAENFLHMMFSVPYRDYEATPEVAHALNMFLVLHADHEQNCSTSTVRMVASSGANMFASVSAGVNALWGPLHGGANMGVIEMLDEIRTTGIKPQDYINRVKDKKSGVKLMGFGHRVYRNFDPRARILKDAADKLLDAMHITDPLLDIAREVEQAALADDYFASRRLYPNVDFYSGIILRAIGIPVDMFTVMFAIGRTPGWIAHFREVSENPAQRIYRPRQVYTGAQLSEWQPRSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDX5</accession>
    <name>A0A1Q2CDX5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05280</name>
        <name evidence="3" type="ORF">SAMN05428934_1033</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY65064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44297">
        <property type="protein sequence ID" value="AQP44297"/>
        <property type="gene ID" value="RPIT_05280"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY65064">
        <property type="protein sequence ID" value="SDY65064"/>
        <property type="gene ID" value="SAMN05428934_1033"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05280"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544441" evidence="1">
        <location>
            <begin position="36"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY65064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="263" mass="28770" checksum="81B07D29726F6738" modified="2017-04-12" version="1">MKPIGSQRGSQRFVRLLLALVLGVAAAVVALPAQAVDVYTTPGKHNHNGRLWNTECEMYSSNVERCRTDIWAYTVVLEGGRYVERAGWAFNNLTYKKSPRATWEAWSPLVTPGVHDVDGRLWKTECDTSWTGGNACRSMIFATVVEADGDSFKTTTKYVFNNIVHLSPVPCPVSQQLLRSGTNRSDAVIQGCERSAADTSWTAVDFSIAGADDEIVMATALFRLGSDGWIYKAHNGFASSGFCGWATAMKAPADLADHFPYCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE00</accession>
    <name>A0A1Q2CE00_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA topoisomerase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="3">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_05460</name>
        <name evidence="8" type="ORF">SAMN05428934_10339</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY66126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05460"/>
    <dbReference type="EnsemblBacteria" id="AQP44328">
        <property type="protein sequence ID" value="AQP44328"/>
        <property type="gene ID" value="RPIT_05460"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY66126">
        <property type="protein sequence ID" value="SDY66126"/>
        <property type="gene ID" value="SAMN05428934_10339"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05460"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034335">
        <property type="term" value="F:DNA negative supercoiling activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002288">
        <property type="entry name" value="DNA_gyrase_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00986">
        <property type="entry name" value="DNA_gyraseB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="465"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="431"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY66126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="691" mass="76109" checksum="395B2E0997BEB290" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE14</accession>
    <name>A0A1Q2CE14_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase</fullName>
            <ecNumber evidence="3">4.2.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_05680</name>
        <name evidence="6" type="ORF">SAMN05428934_10383</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.-.-" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05680"/>
    <dbReference type="EnsemblBacteria" id="AQP44364">
        <property type="protein sequence ID" value="AQP44364"/>
        <property type="gene ID" value="RPIT_05680"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67207">
        <property type="protein sequence ID" value="SDY67207"/>
        <property type="gene ID" value="SAMN05428934_10383"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05680"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="YbaK_deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004369">
        <property type="entry name" value="Prolyl-tRNA_editing_YbaK/EbsC"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="YbaK_EbsC"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_edit" evidence="4">
        <location>
            <begin position="38"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR006181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY67207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="161" mass="16508" checksum="82444219578E7A89" modified="2017-04-12" version="1">MPRSKGATPALKALASSGIAHTLHEYHHDPRSNSYGLEAASALGVEPERVFKTLVATDGTRLVVGIVPVHRHLDLKALAAVLGVKRLSMADPAEVERATGMVVGGISPVGQRKALSTVLDGSASDHETILVSGGRRGLDVELAPGDLVEVAGAVVAEIAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE63</accession>
    <name>A0A1Q2CE63_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UDP-N-acetylglucosamine 1-carboxyvinyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05960</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP44414">
        <property type="protein sequence ID" value="AQP44414"/>
        <property type="gene ID" value="RPIT_05960"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05960"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
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    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="512" mass="56272" checksum="38DCC12945671D26" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE69</accession>
    <name>A0A1Q2CE69_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05865"/>
    <dbReference type="EnsemblBacteria" id="AQP44398">
        <property type="protein sequence ID" value="AQP44398"/>
        <property type="gene ID" value="RPIT_05865"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05865"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046283">
        <property type="entry name" value="DUF6320"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19845">
        <property type="entry name" value="DUF6320"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="200" mass="21787" checksum="2798794005EC8AAB" modified="2017-04-12" version="1">MELDPVEARLASREIFPAPPLRFDRRQVWAAVVALSVLVLIVSFAAPALVPGLVAPVRTVWLSVAVVWLVVIAAVQRRRNVGSLVGWLVLLLSVAAVVWNQYDGPDFWATTWVIPAICTAANLALGVIVWIVRLDPQEHLAKALLVGLIGLVPGLFVLFGWVATPLPALICVGFSLLVVSLILIIRPRQLGSALRRRLHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE76</accession>
    <name>A0A1Q2CE76_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05890</name>
        <name evidence="3" type="ORF">SAMN05428934_103126</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05890"/>
    <dbReference type="EnsemblBacteria" id="AQP44403">
        <property type="protein sequence ID" value="AQP44403"/>
        <property type="gene ID" value="RPIT_05890"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68361">
        <property type="protein sequence ID" value="SDY68361"/>
        <property type="gene ID" value="SAMN05428934_103126"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05890"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY68361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="267" mass="29170" checksum="B0181B1604800DF6" modified="2017-04-12" version="1">MTTAPLDRTHTQFRRGEAAPLRFRNVLVVEFRKFLATRSNQTLALLTLSSALLVAGLIAAFYDSLFESAANHWLVSAFLIRMPVQYLFAPLIVLLTTSEWGTRSVMTTFTLVPRRGLVIAAKAIVTAVATLLVWGLASALGIASTYLGRDVAGMNTAGMWIPAKDVLLDLLAFCLFMASAFGIGLLVQNSAAAIAIVLVGPMAIQILRQFSEWMSETFAWVDMNGVAQQMQMGGDPGMWPQLLVASVFWVVLPLVGGVWWTFRREAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE93</accession>
    <name>A0A1Q2CE93_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Formate--tetrahydrofolate ligase</fullName>
            <ecNumber evidence="6">6.3.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Formyltetrahydrofolate synthetase</fullName>
            <shortName evidence="6">FHS</shortName>
            <shortName evidence="6">FTHFS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fhs</name>
        <name evidence="7" type="ORF">RPIT_06035</name>
        <name evidence="8" type="ORF">SAMN05428934_103154</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6S)-10-formyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20221"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the formate--tetrahydrofolate ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.3" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY69054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06035"/>
    <dbReference type="EnsemblBacteria" id="AQP44426">
        <property type="protein sequence ID" value="AQP44426"/>
        <property type="gene ID" value="RPIT_06035"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY69054">
        <property type="protein sequence ID" value="SDY69054"/>
        <property type="gene ID" value="SAMN05428934_103154"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06035"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004329">
        <property type="term" value="F:formate-tetrahydrofolate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00477">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01543">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000559">
        <property type="entry name" value="Formate_THF_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020628">
        <property type="entry name" value="Formate_THF_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01268">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00721">
        <property type="entry name" value="FTHFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00722">
        <property type="entry name" value="FTHFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="65"/>
            <end position="72"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY69054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="555" mass="58726" checksum="3958F48965085FCE" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEB2</accession>
    <name>A0A1Q2CEB2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Prephenate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_06100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06100"/>
    <dbReference type="EnsemblBacteria" id="AQP44437">
        <property type="protein sequence ID" value="AQP44437"/>
        <property type="gene ID" value="RPIT_06100"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06100"/>
    <dbReference type="UniPathway" id="UPA00036">
        <property type="reaction ID" value="UER00496"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008977">
        <property type="term" value="F:prephenate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004665">
        <property type="term" value="F:prephenate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003099">
        <property type="entry name" value="Prephen_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02153">
        <property type="entry name" value="PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51176">
        <property type="entry name" value="PDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate/arogenate dehydrogenase" evidence="2">
        <location>
            <begin position="8"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="362" mass="38383" checksum="FA7D0F9657E6C654" modified="2017-04-12" version="1">MNSMGGAVNVLILGAGLVGSSLGLALTRAGYAVRLWDIVSSHSLVAAGLGAGEVSNEATDNPDIVVVATPPAVIPELVAEVLQKFPGAVITDVGSVKAPILAAVAELAPEHSRYVGSHPMAGSQFTGPLTASADLFRDRTWVVTPEGGNSEADVAVVTRLATDVGARVVVMPPDEHDEAVAQVSHVPHLMSILTASHLREVPTDNLRLAGQGIRDVTRIAGSDPGLWRQILTSNAEAVRHELEEVAADLQHLIGVLDRPEELERFLAIGQHGAHSLTGKHGHDPLELVTVTVEIPDEPRALARLFTDIGEEGFNVEDFELNHDPAREIGYLSISVETDVAEQFRANIIARGWTVWAAHRGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEC7</accession>
    <name>A0A1Q2CEC7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Imidazoleglycerol-phosphate dehydratase</fullName>
            <shortName evidence="5">IGPD</shortName>
            <ecNumber evidence="5 6">4.2.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hisB</name>
        <name evidence="7" type="ORF">RPIT_06370</name>
        <name evidence="8" type="ORF">SAMN05428934_103219</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:11040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="EC" id="4.2.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the imidazoleglycerol-phosphate dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.19" evidence="5 6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06370"/>
    <dbReference type="EnsemblBacteria" id="AQP44482">
        <property type="protein sequence ID" value="AQP44482"/>
        <property type="gene ID" value="RPIT_06370"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70768">
        <property type="protein sequence ID" value="SDY70768"/>
        <property type="gene ID" value="SAMN05428934_103219"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06370"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00011"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004424">
        <property type="term" value="F:imidazoleglycerol-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07914">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00076">
        <property type="entry name" value="HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038494">
        <property type="entry name" value="IGPD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000807">
        <property type="entry name" value="ImidazoleglycerolP_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020565">
        <property type="entry name" value="ImidazoleglycerP_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133">
        <property type="entry name" value="PTHR23133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00475">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00954">
        <property type="entry name" value="IGP_DEHYDRATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00955">
        <property type="entry name" value="IGP_DEHYDRATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="4 5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY70768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="202" mass="21375" checksum="0660688557E4C7C2" modified="2017-04-12" version="1">MNRTATIERATSESTITVSIDLDGTGASTISTGVGFYDHMLTALAKHSLIDITVEARGDLHIDGHHTIEDVAICLGQALKDALGDKAGIRRYGHAVVPLDEAVAEVVVDVAGRPYVTCQGEPDGQAYALIGGSGVPYAGSMTYHVFEALALNSGLCLHLTLRSGRDPHHIVEAEFKALARALRQAVERDPRHDGVPSTKGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEE2</accession>
    <name>A0A1Q2CEE2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PAC2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_06125</name>
        <name evidence="2" type="ORF">SAMN05428934_103170</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY69448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06125"/>
    <dbReference type="EnsemblBacteria" id="AQP44440">
        <property type="protein sequence ID" value="AQP44440"/>
        <property type="gene ID" value="RPIT_06125"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY69448">
        <property type="protein sequence ID" value="SDY69448"/>
        <property type="gene ID" value="SAMN05428934_103170"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06125"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008492">
        <property type="entry name" value="DUF774"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019151">
        <property type="entry name" value="Proteasome_assmbl_chaperone_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038389">
        <property type="entry name" value="PSMG2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09754">
        <property type="entry name" value="PAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028754">
        <property type="entry name" value="UCP028754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY69448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="281" mass="30967" checksum="B32A8E3A5C35CF16" modified="2017-04-12" version="1">MQHSSPDALRNPAVVVAFSGWNDAGNAASDIVAHLIAAYPGFDVGTIDGERYYDFQAARPMLHRAADGPWIEWPAIRFRVVQHPDRDLVVVVGPEPNLLWRTFSAEIVGKIKEFSPELVVFLGAMLSDTPHSRPLPVGTYTSDPHVERRFGMEISDYAGPTGMIGVVSQLMLHERVPAASVWVSVPHYVSTPPNPKAQDALLTELETLLKISLDHASIPEDAERWATAVDQLSQQDPDIAEYIEQLEEARDAEEVEGATGDTIAAELEKFLRKQGDDEPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEE7</accession>
    <name>A0A1Q2CEE7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_06495</name>
        <name evidence="2" type="ORF">SAMN05428934_103244</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44502">
        <property type="protein sequence ID" value="AQP44502"/>
        <property type="gene ID" value="RPIT_06495"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71446">
        <property type="protein sequence ID" value="SDY71446"/>
        <property type="gene ID" value="SAMN05428934_103244"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06495"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY71446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="844" mass="88690" checksum="B19894437B3C4DD2" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEH3</accession>
    <name>A0A1Q2CEH3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TIGR03085 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_06465</name>
        <name evidence="2" type="ORF">SAMN05428934_103238</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06465"/>
    <dbReference type="EnsemblBacteria" id="AQP44497">
        <property type="protein sequence ID" value="AQP44497"/>
        <property type="gene ID" value="RPIT_06465"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71266">
        <property type="protein sequence ID" value="SDY71266"/>
        <property type="gene ID" value="SAMN05428934_103238"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06465"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017517">
        <property type="entry name" value="CHP03083_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017519">
        <property type="entry name" value="CHP03085"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03083">
        <property type="entry name" value="TIGR03083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03085">
        <property type="entry name" value="TIGR03085"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY71266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="202" mass="22454" checksum="FA2035E47C684680" modified="2017-04-12" version="1">MTFAKRQRAAILDLMTDVGPFAPTRCGGWQVQDLAAHLYIREHRPAALPGIGVDRFAGLTERIQREELHSRGFTGLVEALRRPGWIMRPLDKLVNTSEFFIHHEDVLRANGRSQTLTPAEQQELWPMAKVLARKAQAGAHLRVVLRRTDTGDEVPMGSGDRTVHVSGLPSELLLHLSGRDADVDITGEPESVDAWRRSVGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEN6</accession>
    <name>A0A1Q2CEN6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC transporter substrate-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Peptide/nickel transport system substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_06855</name>
        <name evidence="4" type="ORF">SAMN05428934_11075</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06855"/>
    <dbReference type="EnsemblBacteria" id="AQP44566">
        <property type="protein sequence ID" value="AQP44566"/>
        <property type="gene ID" value="RPIT_06855"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09603">
        <property type="protein sequence ID" value="SDZ09603"/>
        <property type="gene ID" value="SAMN05428934_11075"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06855"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544450" evidence="1">
        <location>
            <begin position="25"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="78"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ09603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="500" mass="54636" checksum="A4F266BB9594BC76" modified="2017-04-12" version="1">MRRTRLSVGIVLALILAVVSTACSQPQEEVPEARPLVIGATLEPDGLDMTTVAGAGTPFVLLRNVYETLIELDGEGGFKPLLASEWTISDDLLEYTFTLDPAAKFASGEDMVAQDVVDSFERSRSEAATGSIRAKWDPVDTIEALDEDKVLVTLSQPSNMWLYDIAGPAGIVVDPAGVDTLDTQPAGSGPFTFVAWDQGNTLKLQGNPDYWGTATRFGEVTFQYYADPNAMNTAMLSGQLDIISNLTVPQSIGQFEDEERFTIHEGTTDGEVVLGFNHRVPALQDLRVRQAINHAIDREALVDSAWGGKGPLIGSMVPPTDPWYEDLSDTYPYDPEKAKELLAEAGYATGLSLRLRIPTLPYGPPAARFIQAQLGEVGIDVEVEELDFARWLDQVYGAHDYDMTIVSHVEGRDIGNFAQEDYYWGYSNPEFSELIEEADTGTEEEQVAKLQEAARLLAEDAAANWLFLLPNIVITTTEISGVQPNQTSLAFDLTTLAARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEQ6</accession>
    <name>A0A1Q2CEQ6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP synthase gamma chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP synthase F1 sector gamma subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">F-ATPase gamma subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">atpG</name>
        <name evidence="11" type="ORF">RPIT_06670</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ATPase gamma chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06670"/>
    <dbReference type="EnsemblBacteria" id="AQP44535">
        <property type="protein sequence ID" value="AQP44535"/>
        <property type="gene ID" value="RPIT_06670"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06670"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12151">
        <property type="entry name" value="F1-ATPase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00815">
        <property type="entry name" value="ATP_synth_gamma_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035968">
        <property type="entry name" value="ATP_synth_F1_ATPase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000131">
        <property type="entry name" value="ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023632">
        <property type="entry name" value="ATP_synth_F1_gsu_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693">
        <property type="entry name" value="PTHR11693"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00231">
        <property type="entry name" value="ATP-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00126">
        <property type="entry name" value="ATPASEGAMMA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52943">
        <property type="entry name" value="SSF52943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01146">
        <property type="entry name" value="ATPsyn_F1gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00153">
        <property type="entry name" value="ATPASE_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0139">CF(1)</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="256"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="303" mass="33234" checksum="550927AB72C400B5" modified="2017-04-12" version="1">MASSLRELRERRRSVSTTKKITRAMELIAASRIIKAQQAARAADPYTRELTKAVSALADVNDLEHPLLRDVEEPRRSAMLIITSDRGLAGAYSSNVIKAAEQLHAKLVGEGQEVVQYIAGQKGVAYFDFRQRPIEESWTGFSDRPTAANAKEIADVLLEKFLAPVEEGGVEQLHIVSTRFVSMLTQTATARRLLPLVVEDAPVGEEPDSELNPFYDFEPNAQEVLDALLPMFVTNRIYTALLQAAASELASRQRAMKSATDNAQALIEQLTREANQARQAEITQEITEIVGGASALAETAGNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEV8</accession>
    <name>A0A1Q2CEV8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">RNA polymerase sigma factor, sigma-70 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">RNA polymerase subunit sigma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_06960</name>
        <name evidence="10" type="ORF">SAMN05428934_11053</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06960"/>
    <dbReference type="EnsemblBacteria" id="AQP44585">
        <property type="protein sequence ID" value="AQP44585"/>
        <property type="gene ID" value="RPIT_06960"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09137">
        <property type="protein sequence ID" value="SDZ09137"/>
        <property type="gene ID" value="SAMN05428934_11053"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06960"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r1_2" evidence="5">
        <location>
            <begin position="17"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r2" evidence="7">
        <location>
            <begin position="83"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r3" evidence="6">
        <location>
            <begin position="162"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="8">
        <location>
            <begin position="252"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ09137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="310" mass="34290" checksum="6804502A52531A04" modified="2017-04-12" version="1">MNTTARIRTTDGIDGKDAVGLYLDAIAKTPLLTAIEEVELARAIEAGLYAQKVLDGEVETSADATEDELRELAAEGERSMQRFVQANLRLVVSVARKYGRAQMPLLDLVQEGNTGLIRAVEKFDYAKGFKFSTYATWWVRQAISRGIAQQGRIVRLPVHVAEQVNQVSAVRRNLERTLGRDPELSEIAEELGLEESKVVDLLRYARDHVSLDAPVEADGDTALGDLIARETSPGPDEMVLDAEERARLEGMLASLDERSQDVVRRRYGLLDGRQAKLADIGTHWGITAERVRQIERQALAQLRTSQGVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEX8</accession>
    <name>A0A1Q2CEX8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TIGR02453 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44674">
        <property type="protein sequence ID" value="AQP44674"/>
        <property type="gene ID" value="RPIT_07510"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07510"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012808">
        <property type="entry name" value="CHP02453"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015996">
        <property type="entry name" value="UCP028451"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36452">
        <property type="entry name" value="PTHR36452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09365">
        <property type="entry name" value="DUF2461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028451">
        <property type="entry name" value="UCP028451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02453">
        <property type="entry name" value="TIGR02453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="214" mass="24220" checksum="E7E8AB85D4873315" modified="2017-04-12" version="1">MSTFQGIPLGAVDFYEDLEQDNSREWWLANKPRYDDDVRAPLEALGALLEAEFGTPKLFRPNRDVRFSADKSPYKTHQGLVVAPVDGMGWYVQVSADGLMTAGGWWADRPELVARYREVFEDEDAGGELQDLLGALREAGYVVGGERLKSRPRGVDADHPHLELLRHRSLTATREYGEPEWLPTAELLEHVAADWRAYRPLMQWLAKRLGGKTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF10</accession>
    <name>A0A1Q2CF10_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_07340</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07340"/>
    <dbReference type="EnsemblBacteria" id="AQP44645">
        <property type="protein sequence ID" value="AQP44645"/>
        <property type="gene ID" value="RPIT_07340"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07340"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003305">
        <property type="entry name" value="CenC_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041542">
        <property type="entry name" value="GH43_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02018">
        <property type="entry name" value="CBM_4_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17851">
        <property type="entry name" value="GH43_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010170017" evidence="5">
        <location>
            <begin position="21"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="domain" description="CBM-cenC" evidence="6">
        <location>
            <begin position="397"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="GH43_C2" evidence="7">
        <location>
            <begin position="560"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="853"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="856"/>
            <end position="884"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="1029" mass="111632" checksum="FBFD8EC59CB81A15" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF48</accession>
    <name>A0A1Q2CF48_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">(R)-citramalate synthase</fullName>
            <ecNumber evidence="4">2.3.1.182</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_07940</name>
        <name evidence="12" type="ORF">SAMN05428934_11328</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + H2O + pyruvate = (3R)-citramalate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19045"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30934"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.182"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-isoleucine biosynthesis; 2-oxobutanoate from pyruvate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the alpha-IPM synthase/homocitrate synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.182" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07940"/>
    <dbReference type="EnsemblBacteria" id="AQP44744">
        <property type="protein sequence ID" value="AQP44744"/>
        <property type="gene ID" value="RPIT_07940"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16521">
        <property type="protein sequence ID" value="SDZ16521"/>
        <property type="gene ID" value="SAMN05428934_11328"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07940"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00066"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043714">
        <property type="term" value="F:(R)-citramalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005675">
        <property type="entry name" value="Citramal_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43538">
        <property type="entry name" value="PTHR43538"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="SSF110921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00977">
        <property type="entry name" value="citramal_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="10">
        <location>
            <begin position="11"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDZ16521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="525" mass="57203" checksum="7B6B7B2EA299A215" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFB9</accession>
    <name>A0A1Q2CFB9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-isopropylmalate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_07945</name>
        <name evidence="4" type="ORF">SAMN05428934_11329</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07945"/>
    <dbReference type="EnsemblBacteria" id="AQP44745">
        <property type="protein sequence ID" value="AQP44745"/>
        <property type="gene ID" value="RPIT_07945"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16542">
        <property type="protein sequence ID" value="SDZ16542"/>
        <property type="gene ID" value="SAMN05428934_11329"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07945"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iso_dh" evidence="2">
        <location>
            <begin position="5"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ16542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="350" mass="36761" checksum="FC41AB1BB084A9EA" modified="2017-04-12" version="1">MTSSNIAVIGGDGIGPEVTAEALKALTAVAGADAFNFVHYDLGAERWQRTGEVLPDSVLDELKGVDAIVLGAVGAAPGSKAIPSGLLERGLLLKLRFAFDHAVNLRPSKLYPGVPTPLAPRIVDGKTVDFVVVREGTEGLYCGNGGAVRVGTPHELATEVSVNTAYGVERVVRDAYRRAQARRGHLTLLHKHNVLVNAGSLWNRIFTEVGQEFPDVEQKYLHIDAAMIALVVDPSQFDVIVTDNLFGDIVTDLAAAVTGGIGLAASANINPTGEYPSMFEPVHGSAPDIAGQGIADPTAAISSMALLLDHLGKPELAKRIDDAVTADIEARGSEKLGTVEIGDRIAARLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFI3</accession>
    <name>A0A1Q2CFI3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Acylphosphatase</fullName>
            <ecNumber evidence="3 4">3.6.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_08755</name>
        <name evidence="8" type="ORF">SAMN05428934_10761</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>an acyl phosphate + H2O = a carboxylate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="3.6.1.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acylphosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.7" evidence="3 4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08755"/>
    <dbReference type="EnsemblBacteria" id="AQP44868">
        <property type="protein sequence ID" value="AQP44868"/>
        <property type="gene ID" value="RPIT_08755"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97532">
        <property type="protein sequence ID" value="SDY97532"/>
        <property type="gene ID" value="SAMN05428934_10761"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08755"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003998">
        <property type="term" value="F:acylphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020456">
        <property type="entry name" value="Acylphosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001792">
        <property type="entry name" value="Acylphosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036046">
        <property type="entry name" value="Acylphosphatase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017968">
        <property type="entry name" value="Acylphosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47268">
        <property type="entry name" value="PTHR47268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00708">
        <property type="entry name" value="Acylphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00112">
        <property type="entry name" value="ACYLPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54975">
        <property type="entry name" value="SSF54975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00150">
        <property type="entry name" value="ACYLPHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51160">
        <property type="entry name" value="ACYLPHOSPHATASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acylphosphatase-like" evidence="6">
        <location>
            <begin position="17"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY97532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="103" mass="10919" checksum="204B8E61F62B3FB8" modified="2017-04-12" version="1">MTGHAAPEGRAPGSRVAREAVVSGRVQGVGFRWSARAQAERLGVSGHVRNLADGRVEAQFEGDADAVAAFEGWLRHGPSAAQVDRVVAADREVTGARGFRIER</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFI7</accession>
    <name>A0A1Q2CFI7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Trigger factor</fullName>
            <shortName evidence="9">TF</shortName>
            <ecNumber evidence="3 9">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">PPIase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">tig</name>
        <name evidence="14" type="ORF">RPIT_08820</name>
        <name evidence="15" type="ORF">SAMN05428934_10774</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1T</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1</strain>
        </source>
    </reference>
    <reference evidence="14" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="9">About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.</text>
    </comment>
    <comment type="domain">
        <text evidence="9">Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the FKBP-type PPIase family. Tig subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="3 9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08820"/>
    <dbReference type="EnsemblBacteria" id="AQP44881">
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        <location>
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        <source>
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        <source>
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        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
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    <sequence length="463" mass="50976" checksum="D2796B5B49A828E3" modified="2017-04-12" version="1">MPSTVQKLSPTRAKLTVEIPFSDLKPYLDQAYKEIAEQVNIPGFRKGKVPAAVIDQRVGRGLVLQEAINEAIPVAYNQAVQEAQLVPMSQPEVDITKLEDKELVEFTAEVDVRPEVELPDFASITATVDAPGSIDELVDERIELLRERFATTTEVDRAAQEGDVLTIDLVASQDGEPLPEATAEGVSYKVGQERNMLDGLDAAVTGLKAGESTTFTSELVGGQFRGQEAEIAVTVQKVLEQQLPDVDDDFAQLISEFDTVDEMKDDLRKGAAQQVEADQIVDARDKVLEAVLEKVDFELPEGLLARELEARRAEVQRQLNAGGLTVEQYLETAEDEEAKDADEFWATIDERSTQALKAQVILDVYADEKAVDVSQQELTELIFRKAQQNNTSPQDEINHMMEHNHMPEWMQEIRRSKALAAICAEATVTDAEGNAVDTSLPVVDSAEAEDDVVDGEVEETPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFI8</accession>
    <name>A0A1Q2CFI8_9ACTN</name>
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        <submittedName>
            <fullName evidence="5">Cobalt ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
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        </submittedName>
    </protein>
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        <lineage>
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 7">RP1T</strain>
        </source>
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    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
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        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <ligand>
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        <source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44830.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY96429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="520" mass="55302" checksum="DB173A5A600006AB" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFL4</accession>
    <name>A0A1Q2CFL4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein often found in actinomycetes clustered with signal peptidase and/or RNaseHII</fullName>
        </submittedName>
    </protein>
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    </gene>
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        <lineage>
            <taxon>Bacteria</taxon>
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    </organism>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="protein sequence ID" value="SDY96605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08550"/>
    <dbReference type="EnsemblBacteria" id="AQP44835">
        <property type="protein sequence ID" value="AQP44835"/>
        <property type="gene ID" value="RPIT_08550"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY96605">
        <property type="protein sequence ID" value="SDY96605"/>
        <property type="gene ID" value="SAMN05428934_10721"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08550"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019592">
        <property type="entry name" value="DUF2469"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10611">
        <property type="entry name" value="DUF2469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <source>
            <dbReference type="EMBL" id="AQP44835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY96605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="103" mass="12132" checksum="A37015B20037565C" modified="2017-04-12" version="1">MSAEDLEQYESKLELDLYREYKDVVGIFTYAVETERRFYLCNAVDLKVRTEGGDVYYEVSMGDAWVWDMYRPARFVKSAKVLTFRDVSIEEIAHSDLQVPENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFS0</accession>
    <name>A0A1Q2CFS0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_09270</name>
        <name evidence="2" type="ORF">SAMN05428934_1263</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000026">
        <property type="protein sequence ID" value="SDZ23669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44953">
        <property type="protein sequence ID" value="AQP44953"/>
        <property type="gene ID" value="RPIT_09270"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ23669">
        <property type="protein sequence ID" value="SDZ23669"/>
        <property type="gene ID" value="SAMN05428934_1263"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09270"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ23669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="223" mass="25883" checksum="6704B844337936E5" modified="2017-04-12" version="1">MSDPRSAIAGIENWCHPRAPEEWQDLWGRLGNGHGIDPYREYWIIYRGWGPEGVDLRFSAHAVDVREDWTAFRALYDLACTSDERLTALREAGYGFQIVTSTEHTPEEVAEYRQWFSEIDLGDSEAQAEYLYHTVLLEVIDIDAVEVTEADLVEFTGEFPSIKNWRRATQSLWMVDFSEYPRPLKRRGVMAVSLAINYEQHNILQRVHRHHNAHVRGAHRNDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFT9</accession>
    <name>A0A1Q2CFT9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09435</name>
        <name evidence="3" type="ORF">SAMN05428934_102420</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY60267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44979">
        <property type="protein sequence ID" value="AQP44979"/>
        <property type="gene ID" value="RPIT_09435"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY60267">
        <property type="protein sequence ID" value="SDY60267"/>
        <property type="gene ID" value="SAMN05428934_102420"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09435"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043733">
        <property type="entry name" value="DUF5677"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18928">
        <property type="entry name" value="DUF5677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="363"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY60267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="393" mass="43891" checksum="EC928F0A5080AEB9" modified="2017-04-12" version="1">MNISTTTALWRARLRYWLAGRRRVTLRLLGRASDSSDAYLRIAQALEEKHESSGMSSEEAMERGLVEALEILTEHGPPQVAAALKADGPRMLAEHRRLDRGFEKRIRQRWGTALDLYYMIAVACQEVGAEGYQEANQCDEGSESERALLEAMSGLQARACRQSLEVLSLLETGFPKAAHAVSRSMHEGAVVASVLTEYGSTPEHADIGTRFLLFDHITNLMDAEEYQRYAERLKHEPFTDQEMAALRTTKAEVLERFPDLDRKMGWAGDLPGLRKRTFEELEVIAGIDHLRPYYTWASHEVHAYPKGVRLNQSGLDGDLWKLAGRTNAGLADPAQGALIALNQVTASMLTVPGVASPSRIVASRATMALLDEAREEFARIERELADERTLTVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFY4</accession>
    <name>A0A1Q2CFY4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_09385</name>
        <name evidence="2" type="ORF">SAMN05428934_102430</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY60556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44970">
        <property type="protein sequence ID" value="AQP44970"/>
        <property type="gene ID" value="RPIT_09385"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY60556">
        <property type="protein sequence ID" value="SDY60556"/>
        <property type="gene ID" value="SAMN05428934_102430"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09385"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY60556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="154" mass="17320" checksum="42E209C371BF9CB7" modified="2017-04-12" version="1">MSIDAEYPGDPRHPEHTDWLLELGRATYAAAGLSGIAVDLLRVHSGFESEDLYKDPLGRLLDKLRRTPPAVDGIEDFIALSEEALVVRNDVLHALPVMHGLHRRRSDDLGYVRNYYDLASLWEATQVIQNARRKGNEVLYADGGEAVRRWVESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFZ8</accession>
    <name>A0A1Q2CFZ8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_09740</name>
        <name evidence="6" type="ORF">SAMN05428934_102357</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY58582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09740"/>
    <dbReference type="EnsemblBacteria" id="AQP45033">
        <property type="protein sequence ID" value="AQP45033"/>
        <property type="gene ID" value="RPIT_09740"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY58582">
        <property type="protein sequence ID" value="SDY58582"/>
        <property type="gene ID" value="SAMN05428934_102357"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09740"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="136"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY58582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="204" mass="21087" checksum="12973B7D46DCE303" modified="2017-04-12" version="1">MIRVLVVDDHPVVRSGLRALLAGEPRLDVVGAASTGEEALSMAAELTPDVVLCDLRLGAGLDGVGVTAALRPHGPAVLILTTYDNDSDIARAVLAGAAGYLLKDADPSVIVQGIADAAAGKLVLSVDLEGRVIERLTTGVPSLSARELDVMGLVAEGLTNREIARRLFISEGTVKTHLVHAFAKLGADSRTGAVAAARRHGLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG25</accession>
    <name>A0A1Q2CG25_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_09935</name>
        <name evidence="2" type="ORF">SAMN05428934_102319</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY57413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09935"/>
    <dbReference type="EnsemblBacteria" id="AQP45069">
        <property type="protein sequence ID" value="AQP45069"/>
        <property type="gene ID" value="RPIT_09935"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57413">
        <property type="protein sequence ID" value="SDY57413"/>
        <property type="gene ID" value="SAMN05428934_102319"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09935"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY57413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="132" mass="14313" checksum="B5DFE0CFAC22730F" modified="2017-04-12" version="1">MRIVITGASGKAGQATLRHFAELPHYDVLGTDLAPRPAWYAGDFLRADLAEYGEAVDVLSGADAVVHHANNPRRRDLHRLLDVPTREALAVTHPGITVPDHVSEFGTLLSNSAAKDALGFAPQHSWRHEVHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG79</accession>
    <name>A0A1Q2CG79_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC-type multidrug transport system, ATPase and permease component</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">Multidrug ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_10225</name>
        <name evidence="12" type="ORF">SAMN05428934_102260</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45121">
        <property type="protein sequence ID" value="AQP45121"/>
        <property type="gene ID" value="RPIT_10225"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55843">
        <property type="protein sequence ID" value="SDY55843"/>
        <property type="gene ID" value="SAMN05428934_102260"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10225"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="318"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="96"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="408"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="441"/>
            <end position="448"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP45121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY55843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="646" mass="69272" checksum="2329021CF9B4BAF2" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG82</accession>
    <name>A0A1Q2CG82_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Succinate--CoA ligase [ADP-forming] subunit alpha</fullName>
            <ecNumber evidence="2">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Succinyl-CoA synthetase subunit alpha</fullName>
            <shortName evidence="2">SCS-alpha</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">sucD</name>
        <name evidence="7" type="ORF">RPIT_09865</name>
        <name evidence="8" type="ORF">SAMN05428934_102333</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 5">
            <text>ATP + CoA + succinate = ADP + phosphate + succinyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Heterotetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY57851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09865"/>
    <dbReference type="EnsemblBacteria" id="AQP45055">
        <property type="protein sequence ID" value="AQP45055"/>
        <property type="gene ID" value="RPIT_09865"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57851">
        <property type="protein sequence ID" value="SDY57851"/>
        <property type="gene ID" value="SAMN05428934_102333"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09865"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01988">
        <property type="entry name" value="Succ_CoA_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033847">
        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005810">
        <property type="entry name" value="CoA_lig_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001553">
        <property type="entry name" value="SucCS_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01019">
        <property type="entry name" value="sucCoAalpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="1 2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="CoA_binding" evidence="6">
        <location>
            <begin position="4"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="2">
        <location>
            <begin position="17"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="2">
        <location>
            <begin position="100"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="2 3">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit beta</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001553-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY57851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="307" mass="31861" checksum="6F969EACA692FA7A" modified="2017-04-12" version="1">MSIFINASSRVLVQGMTGKEGRKHTQRMIMSGTRVVGGVTPGKAGESVLFEEDPVPVFGSMVEAVAATQADVSVVFVPPKYAKAAVLESIEAEIGLCVVITEGIPVRDSVEFHSAARDSGTRIIGPNCPGLISPGKSNVGIIPAHIAGPGRIGLVSKSGTLTYQMMYELRDHGFSTAVGIGGDPVVGTPHIDVLQAFEDDDETDVIVMIGEIGGDAEERAAEYIQRNITKPVVGYVAGFTAPPGRTMGHAGAIITGSKGTAAAKKEALEAAGVLVGETPSLTASLARDAIAKMRVNQSRNVTPKRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG98</accession>
    <name>A0A1Q2CG98_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine acetyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.30</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_10335</name>
        <name evidence="11" type="ORF">SAMN05428934_102238</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + L-serine = CoA + O-acetyl-L-serine</text>
            <dbReference type="Rhea" id="RHEA:24560"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.3.1.30"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.30" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10335"/>
    <dbReference type="EnsemblBacteria" id="AQP45141">
        <property type="protein sequence ID" value="AQP45141"/>
        <property type="gene ID" value="RPIT_10335"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55267">
        <property type="protein sequence ID" value="SDY55267"/>
        <property type="gene ID" value="SAMN05428934_102238"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10335"/>
    <dbReference type="UniPathway" id="UPA00136">
        <property type="reaction ID" value="UER00199"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009001">
        <property type="term" value="F:serine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03354">
        <property type="entry name" value="LbH_SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045304">
        <property type="entry name" value="LbH_SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010493">
        <property type="entry name" value="Ser_AcTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042122">
        <property type="entry name" value="Ser_AcTrfase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005881">
        <property type="entry name" value="Ser_O-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06426">
        <property type="entry name" value="SATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00971">
        <property type="entry name" value="SATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01172">
        <property type="entry name" value="cysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SATase_N" evidence="9">
        <location>
            <begin position="12"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP45141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY55267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="270" mass="29164" checksum="D03CB4B19B1D6C40" modified="2017-04-12" version="1">MDPTRIVPDDQIWAAIQEECAEVARNEPLLAGFLYTVILSQPDLEDALSYILASKLDNTTLPALSLRDIIHDVLIDDECIQRAVRADLQAVVSRDPACPGYSNPLLYFKGFQSIQAYRVANFYWEHNRKPLAHYLQSRISEVFAVDIHPGARIGKGIMFDHATSVVIGETAVVEDEFSMLHEVTLGGSGKEGGDRHPKIGRGVMIGAGAKVLGNIRVGEGAKIGAGSVVLKDVPPHTTVAGVPARVVNLPPSALPAHDMDQAFDPSVPIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGD7</accession>
    <name>A0A1Q2CGD7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exodeoxyribonuclease 7 large subunit</fullName>
            <ecNumber evidence="5">3.1.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Exodeoxyribonuclease VII large subunit</fullName>
            <shortName evidence="5">Exonuclease VII large subunit</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">xseA</name>
        <name evidence="8" type="ORF">RPIT_10520</name>
        <name evidence="9" type="ORF">SAMN05428934_102201</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterooligomer composed of large and small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the XseA family.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.6" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY54162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10520"/>
    <dbReference type="EnsemblBacteria" id="AQP45176">
        <property type="protein sequence ID" value="AQP45176"/>
        <property type="gene ID" value="RPIT_10520"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY54162">
        <property type="protein sequence ID" value="SDY54162"/>
        <property type="gene ID" value="SAMN05428934_102201"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10520"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04489">
        <property type="entry name" value="ExoVII_LU_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00378">
        <property type="entry name" value="Exonuc_7_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003753">
        <property type="entry name" value="Exonuc_VII_L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020579">
        <property type="entry name" value="Exonuc_VII_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025824">
        <property type="entry name" value="OB-fold_nuc-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30008">
        <property type="entry name" value="PTHR30008"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02601">
        <property type="entry name" value="Exonuc_VII_L"/>
        <property type="match status" value="1"/>
    </dbReference>
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        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF02601"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP45176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY54162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="409" mass="45046" checksum="4192C76B8A9A2205" modified="2017-04-12" version="1">MSLTSSPEQPQPLGRVIMAVKDWVGRCGEIWVDAQIVEIKRRSGPTQFLTFRDRIADMSAQVTASSLVLDAAGPLPEGSRVTARIRPRVWERNSSLSFECLELQVEGEGKLLARLEQLKRKLQAEGLFDAHRKRRLPVVPRLIGLVTGKDSDAERDVVTNVLRRWPAANIRTRHAIVQGARSAESVMEAVAALDADAEVDVIIIARGGGSLEDLLSFSDEGLVRLVAGARTPIVTAIGHERDAPIVDLVADVRASTPTDAAKLVVPDHRQESAGVADARERLRRAVETRLTTLERQLDDLRSRPVLVDPTSAFVAHFDRLVHLRHRLNAAVESTLREQEATLRTAVGTIRALSPKRTLERGYAVLVDDRHRSVSAVDDTQIGARIHAYLADGQLALDVVEQTKKEISHD</sequence>
</entry>
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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            <begin position="1"/>
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    </evidence>
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</entry>
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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            <dbReference type="PubMed" id="26869509"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
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        </cofactor>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY52168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10830"/>
    <dbReference type="EnsemblBacteria" id="AQP45228">
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    </dbReference>
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        <property type="protein sequence ID" value="SDY52168"/>
        <property type="gene ID" value="SAMN05428934_102138"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10830"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
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    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="F:dimethyl sulfoxide reductase activity"/>
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        <property type="term" value="F:molybdenum ion binding"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="8">
        <location>
            <begin position="53"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
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        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
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    </evidence>
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    </evidence>
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    </evidence>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            </authorList>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
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        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY48517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11430"/>
    <dbReference type="EnsemblBacteria" id="AQP45332">
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        <property type="gene ID" value="RPIT_11430"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY48517">
        <property type="protein sequence ID" value="SDY48517"/>
        <property type="gene ID" value="SAMN05428934_10218"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11430"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transket_pyr" evidence="4">
        <location>
            <begin position="471"/>
            <end position="644"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
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    </evidence>
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            <dbReference type="SMART" id="SM00861"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45332.1"/>
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    </evidence>
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            <dbReference type="EMBL" id="SDY48517.1"/>
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    </evidence>
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            <dbReference type="Proteomes" id="UP000188324"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
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    </evidence>
    <sequence length="818" mass="89569" checksum="2DCF60FE077D32FA" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
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            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="101" mass="10405" checksum="507258450D92F8D9" modified="2017-04-12" version="1">MNSLAAILTTPRRGVVAAIDLYQRRLSPRKGFTCAHLAAGGTRSCSAVIRAIVADEGLVAGFVPTVAQFAACARAASTLRSGPQAVQGVCCCGGIPIPFRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGY8</accession>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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                <person name="Schumann P."/>
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            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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    <reference evidence="2 4" key="2">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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    </dbReference>
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        <property type="gene ID" value="SAMN05428934_106134"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45381.1"/>
        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="181" mass="20122" checksum="23C287E7B441B25E" modified="2017-04-12" version="1">MAKRPKRHQLKEAGAVQAPVDDAVFGVDEDDEIDLAFDAEDPLLEEFIRDMSLQTCDYCASPVQWIEPEELIETYPAEVDDVLFDLDLDVGDILMSWVCTECPNFSIIGEDFESQYLDIQGDVPCLECEATTQAIDPAQASHLDREGYLKAKREFGAQAVLDGYAQRCPGCGNVDYYPAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGY9</accession>
    <name>A0A1Q2CGY9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mechanosensitive ion channel</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Small-conductance mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_11710</name>
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    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45382">
        <property type="protein sequence ID" value="AQP45382"/>
        <property type="gene ID" value="RPIT_11710"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93601">
        <property type="protein sequence ID" value="SDY93601"/>
        <property type="gene ID" value="SAMN05428934_106133"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11710"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY93601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="275" mass="29525" checksum="5A58E2C4F94C1B56" modified="2017-04-12" version="1">MIDLPPITWQMVLTGLAVVLAGILVSYVARFLAARLLSLRDRSPSSVRVFSQVIQVVIIILTVAAAMTVVFPSVKPVDVLGGITIISLAAGIAFQTVLGNMFAGMVILARDRFRVGDQIRIFDHAGTVSEMGLSHTSLRTFDGRLVVIPNSALHSELVTVQTGYERVRSTVNVDLDDAVDLGKAREVALEAMKCIPSVLEDPAPDALLREIGTATVRMELRFWSGARQLETRTAQDAVIQSVVEAFRTHDVKSGDEVVTVKLVSGVPGAPQTPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH73</accession>
    <name>A0A1Q2CH73_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_12185</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12185"/>
    <dbReference type="EnsemblBacteria" id="AQP45468">
        <property type="protein sequence ID" value="AQP45468"/>
        <property type="gene ID" value="RPIT_12185"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12185"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="3">
        <location>
            <begin position="394"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="214"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="248"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="487" mass="51252" checksum="FC4E2173E13990D7" modified="2017-04-12" version="1">MRPTWGRTVAKEERQMVPIAAWRVTYTPGDWLVLAGPTTAVVMLPAPSRATAVITELWEDIVQARSLDALLKCVADLGLDRMPDFAAFHWDSDGLHGLTRGLVKVLDDRSGETVLDGRGTVTWREEHLGGERRLRVDLGSGESPDSVQLPLLVGAATVSSLTLSTDSDDLVRFPSAEGTGLLTPLAILDDAGDEGQDADEMDLAEASPAAVDDDAFDHEHDPYDDDHDPYGDEVDLYDDEPMSQPTPFAGFSPIPPPASPDADEPFLAPPFAAGLSPVAVFDEPASLSSPSAEHTLAAPQSDEEDDSDLIFSLGRSAAAPDAPFSSGTPADAPAQPGGVLVVTCLNGHPNEPGARLCRICMGPVDSSRAQRMPRPELAAVHTTQGQFAEVGEGVIIGRAPDPAKGPAGATVLRVTSPSNDISRSHLLVTTSGWSVHVTDLNSTNGTTVLPVSGQPFALREGDSVVVELGTVLDLGDGVSVRIEPPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHB2</accession>
    <name>A0A1Q2CHB2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative N-acetylmannosamine-6-phosphate 2-epimerase</fullName>
            <ecNumber evidence="5">5.1.3.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ManNAc-6-P epimerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nanE</name>
        <name evidence="6" type="ORF">RPIT_12390</name>
        <name evidence="7" type="ORF">SAMN05428934_104207</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>an N-acyl-D-glucosamine 6-phosphate = an N-acyl-D-mannosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23932"/>
            <dbReference type="ChEBI" id="CHEBI:57599"/>
            <dbReference type="ChEBI" id="CHEBI:57666"/>
            <dbReference type="EC" id="5.1.3.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Amino-sugar metabolism; N-acetylneuraminate degradation; D-fructose 6-phosphate from N-acetylneuraminate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NanE family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.9" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY80748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12390"/>
    <dbReference type="EnsemblBacteria" id="AQP45502">
        <property type="protein sequence ID" value="AQP45502"/>
        <property type="gene ID" value="RPIT_12390"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY80748">
        <property type="protein sequence ID" value="SDY80748"/>
        <property type="gene ID" value="SAMN05428934_104207"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12390"/>
    <dbReference type="UniPathway" id="UPA00629">
        <property type="reaction ID" value="UER00682"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047465">
        <property type="term" value="F:N-acylglucosamine-6-phosphate 2-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009385">
        <property type="term" value="F:N-acylmannosamine-6-phosphate 2-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006051">
        <property type="term" value="P:N-acetylmannosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019262">
        <property type="term" value="P:N-acetylneuraminate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04729">
        <property type="entry name" value="NanE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01235">
        <property type="entry name" value="ManNAc6P_epimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007260">
        <property type="entry name" value="NanE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36204">
        <property type="entry name" value="PTHR36204"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04131">
        <property type="entry name" value="NanE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY80748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="226" mass="23333" checksum="54930D024521FE63" modified="2017-04-12" version="1">MNAILDSLRGQLVVSCQAYPGEPMLDPRTMSQVAQAAVTGGAAAIRAKGLDDLRAIRAAVDVPIIGLVKEGATGVYITPTLESCIAVAETGCEIVALDGTRRDRPDGLTLAETVACLKERFPEVLVMADCGSAGDAAAAQEAGADIIGTTLVGYSGERPKTDGPDWEAIDEIIALADRPVLVEGRVHSPADAAESIRRGAWGVVVGTAITHPATITSWFAKAVAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHD0</accession>
    <name>A0A1Q2CHD0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sulfur transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_12165</name>
        <name evidence="10" type="ORF">SAMN05428934_10643</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0394 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY91616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12165"/>
    <dbReference type="EnsemblBacteria" id="AQP45465">
        <property type="protein sequence ID" value="AQP45465"/>
        <property type="gene ID" value="RPIT_12165"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY91616">
        <property type="protein sequence ID" value="SDY91616"/>
        <property type="gene ID" value="SAMN05428934_10643"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12165"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007272">
        <property type="entry name" value="Sulf_transp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04143">
        <property type="entry name" value="Sulf_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Sulf_transp" evidence="8">
        <location>
            <begin position="18"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY91616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="355" mass="37061" checksum="F6B3DBBCD6AD4A56" modified="2017-04-12" version="1">MIISGLAIGLLLGFVFQRGRFCVTGAFRDVWLSGSKRWLTAFLLAILVQAVLVQGLLGQDLIVAKVPAIAWLGVIGGSFLFGIGIVLAGGCATGTYYRSGEGLIGSWIALVFYALLASFMKYGALQPVTTAALADKTELTTIHDSLGISAWLLVLVLAGVVGWLVWTQRVARQVVARPAARRSGLAHLLLERPWSPYASAILVGVIAAAAYPLSNATGRNSGLGITTPSANIVNFLATGDASRIDWGVLFVLGLIPGSYIAAKLAGEFRLRAPDAPTAIRAIAGGSLMGVGAAIAGGCTIGNALVQTALFSYQGWTAFLFTFLGVGFAARFFVQTHRRAGAQAVPVAPSDLVRAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHE7</accession>
    <name>A0A1Q2CHE7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_12570</name>
        <name evidence="4" type="ORF">SAMN05428934_104172</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY79806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12570"/>
    <dbReference type="EnsemblBacteria" id="AQP45534">
        <property type="protein sequence ID" value="AQP45534"/>
        <property type="gene ID" value="RPIT_12570"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY79806">
        <property type="protein sequence ID" value="SDY79806"/>
        <property type="gene ID" value="SAMN05428934_104172"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12570"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041484">
        <property type="entry name" value="TetR_C_25"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17933">
        <property type="entry name" value="TetR_C_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY79806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="220" mass="23899" checksum="C6331C12FFF7B168" modified="2017-04-12" version="1">MSSADLQAHARIRDAAIRLFGRQGVKATTIRQIAEEVGVSPALVIHHFGSKDGLRRACDEWMMDRLTASKTAALSGQEAFQWTMRAQAEFQPFYPYIAASISEGGDNAERLFDAMCQLTREMFAVGVPAGTLRNPADLEAMVTVLVAFSLGATTLERQVARRLGGATMFDSDVLRRYSLATTDLFTHGLFADSRMLDQLRAAFGVDVPGDGITDPDPPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHH3</accession>
    <name>A0A1Q2CHH3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_12730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12730"/>
    <dbReference type="EnsemblBacteria" id="AQP45562">
        <property type="protein sequence ID" value="AQP45562"/>
        <property type="gene ID" value="RPIT_12730"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12730"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="218" mass="22786" checksum="3ABB11095DB9763B" modified="2017-04-12" version="1">MEVSSTLGEFAAVIFDFDGTLADSHAAMVRSYLTWADEFGLDPASLVSFTGMPSAAIAAALLPADQVERASARIDELEVADTDGVVPLPGAVDALAGVPDERRAIATSCTAPLLNARLDAVGLDRPAVVVTRDDVTNGKPDPESFLLAAERLGTDPERCVVFEDAPAGVAAARAAGMAVIGVLTAHTVDELQADWHVNSLADVEFEAIDDGVRITWRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHN2</accession>
    <name>A0A1Q2CHN2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidoglycan glycosyltransferase</fullName>
            <ecNumber evidence="1">2.4.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_13100</name>
        <name evidence="13" type="ORF">SAMN05428934_10467</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY76860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13100"/>
    <dbReference type="EnsemblBacteria" id="AQP45629">
        <property type="protein sequence ID" value="AQP45629"/>
        <property type="gene ID" value="RPIT_13100"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY76860">
        <property type="protein sequence ID" value="SDY76860"/>
        <property type="gene ID" value="SAMN05428934_10467"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13100"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 13" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="Transgly" evidence="11">
        <location>
            <begin position="70"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="10">
        <location>
            <begin position="348"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="649"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="653"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="725"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP45629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY76860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="752" mass="80541" checksum="0848D497C5999555" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHP1</accession>
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            <fullName evidence="3">Uncharacterized protein</fullName>
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        <name evidence="4" type="ORF">SAMN05428934_10473</name>
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        <name type="scientific">Tessaracoccus flavus</name>
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            <taxon>Propionibacteriales</taxon>
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    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13070"/>
    <dbReference type="EnsemblBacteria" id="AQP45624">
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    </dbReference>
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        <property type="gene ID" value="SAMN05428934_10473"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY77026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="200" mass="20953" checksum="0892E6A52BC92A70" modified="2017-04-12" version="1">MSNQDNPAGYPERPEGTGPDYSPNPYGSPQPGGPQYQPSPYGTPNSDNQSAGPYSSTEGPGTTQPQPPYAAPPSGGYSPYPYSASDSGGPSYPSGTFGAPGGRPERGFLGSLFDVSFSSFITPSVVKVAYIISMVIIGIFVLFGVIAALTSGDGLLAVFGLILAPAVGLFYLVLVRMTLEFYYATIRMSEDIHRRLPGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHT7</accession>
    <name>A0A1Q2CHT7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13350"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="311" mass="33085" checksum="FF518CA95698025F" modified="2017-04-12" version="1">MVPDPGGGGGSPAIPGISTPRVILAGFTTNPEVVQAGQDFQVTFTLRNTSTRTRVQNMKITLASADNAFLPANGSSSMFLRRISADDVELGTMNFHSLPSLEERPYQMVISVEYEDTLANAYSTQETVSIPVKQSIRADSSVPQLSPPQLTLGQEASLTFNIFNQGKTKLYNAKATVAEGQAVTAPEVFVGTIEPGTSGAVDMTVMAAEEAVGPVTIVVSYEDVDGKVSTMDKVVEVAVMEPMPIEEPGGWEEPVEEAAFPLVPVLVAAGLLALLLIIALVARGRRRKRREAEDMESLAALGEPLIGPDVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHU7</accession>
    <name>A0A1Q2CHU7_9ACTN</name>
    <protein>
        <submittedName>
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        </submittedName>
        <submittedName>
            <fullName evidence="7">Quaternary ammonium compound-resistance protein SugE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_13235</name>
        <name evidence="7" type="ORF">SAMN05428934_10440</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY76102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45653">
        <property type="protein sequence ID" value="AQP45653"/>
        <property type="gene ID" value="RPIT_13235"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY76102">
        <property type="protein sequence ID" value="SDY76102"/>
        <property type="gene ID" value="SAMN05428934_10440"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13235"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Small_drug/metabolite_transptr"/>
    </dbReference>
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        <property type="entry name" value="Small_multidrug_res"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30561">
        <property type="entry name" value="PTHR30561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00893">
        <property type="entry name" value="Multi_Drug_Res"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY76102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="104" mass="10726" checksum="8FF1E2D4A03523A7" modified="2017-04-12" version="1">MDWVILIASGVLEAVWATALGRSNGLRRPLPTAVFVVASILSLGGLGIALQTLPTGTAYAVWTATGASLTVVWAMLTRVEPASVKKVLLLTGIIACVIGLKVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHW0</accession>
    <name>A0A1Q2CHW0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">D-alanine--D-alanine ligase</fullName>
            <ecNumber evidence="3">6.3.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">D-Ala-D-Ala ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">D-alanylalanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ddl</name>
        <name evidence="7" type="ORF">RPIT_13550</name>
        <name evidence="8" type="ORF">SAMN05428934_11189</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>ATP + 2 D-alanine = ADP + D-alanyl-D-alanine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11224"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="4">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="4">Binds 2 magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the D-alanine--D-alanine ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.4" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ13191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13550"/>
    <dbReference type="EnsemblBacteria" id="AQP45708">
        <property type="protein sequence ID" value="AQP45708"/>
        <property type="gene ID" value="RPIT_13550"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ13191">
        <property type="protein sequence ID" value="SDZ13191"/>
        <property type="gene ID" value="SAMN05428934_11189"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13550"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008716">
        <property type="term" value="F:D-alanine-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00047">
        <property type="entry name" value="Dala_Dala_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005905">
        <property type="entry name" value="D_ala_D_ala"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011095">
        <property type="entry name" value="Dala_Dala_lig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07478">
        <property type="entry name" value="Dala_Dala_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039102">
        <property type="entry name" value="Ddl/VanB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="2 3" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="6">
        <location>
            <begin position="99"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR039102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ13191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="310" mass="32106" checksum="D1EF502AF2DAB22F" modified="2017-04-12" version="1">MTVIVIAGGLSHERDVSLRSGRRVAQALRDAGLDVLETDVNADLVGLIRSTDDAVVVPMLHGGLGEDGALREVLEILGVPFVGPTGASSRLTFDKAIATSVVRGAGLATPRQIALPHDIFRELGAPALMEGIGAQLGYPLVVKPTRSGSALGVTKVDSPAALPSALVAAYAYGTVAVVEQYLSGVEIAVTVLDLGDGATALPPVEIRPESGVYNYESRYTAGATRFVTPAELPDDVLAAAGELAVAAHRALGLRHLSRVDMIVEPDGRPVFFEGNVAPGMTETSLAPLAFEAAGLELSDVFARLVDLARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHZ9</accession>
    <name>A0A1Q2CHZ9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Membrane associated serine protease, rhomboid family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_13750</name>
        <name evidence="9" type="ORF">SAMN05428934_11150</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13750"/>
    <dbReference type="EnsemblBacteria" id="AQP45737">
        <property type="protein sequence ID" value="AQP45737"/>
        <property type="gene ID" value="RPIT_13750"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12523">
        <property type="protein sequence ID" value="SDZ12523"/>
        <property type="gene ID" value="SAMN05428934_11150"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13750"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00643">
        <property type="entry name" value="zf-B_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="252"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="280"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="B box-type" evidence="6">
        <location>
            <begin position="4"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="7">
        <location>
            <begin position="134"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ12523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="300" mass="32186" checksum="6A2E8D1A4AB2B6F2" modified="2017-04-12" version="1">MDDARACYRHPNQPTRITCQRCDRPICPQCMVPGSVGFQCPDCVSEGLKQTRQRSLPYGGTRVDNPKATSVVLIGMSVAVFLAVLATGGTWGTVFNWFSLTPLGRCEAGDAWLDLPAAASCAANGGTWVPGVASGAPWQLITSAFTHSQFLHIGFNMLIIYLLGPQIEQILGRARYLALYFVAALGGAAGVMLFSEWYTSTMGASGAVYGLMGAMLLLAMKHKGDVRGILTWLGLNVVLSFTWSGISWQGHLGGLLGGLAVAAILLYLPRERRATLQWPLIALVAVAFLALIAWRALQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI39</accession>
    <name>A0A1Q2CI39_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PAP2 superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13695</name>
        <name evidence="4" type="ORF">SAMN05428934_11160</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45730">
        <property type="protein sequence ID" value="AQP45730"/>
        <property type="gene ID" value="RPIT_13695"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12722">
        <property type="protein sequence ID" value="SDZ12722"/>
        <property type="gene ID" value="SAMN05428934_11160"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13695"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025749">
        <property type="entry name" value="Sphingomyelin_synth-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14360">
        <property type="entry name" value="PAP2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="PAP2_C" evidence="2">
        <location>
            <begin position="142"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ12722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="217" mass="22882" checksum="723C08BA7FD960FD" modified="2017-04-12" version="1">MANLVVHTVAMEQPLVPNAPSPVGAWATAAGLGALAVVATWLANRVIVGSFADAPRPEDLLFEALPYVRGARWLTVVALVGGLGAFLWVTLRSSPSRIPAVGARIAVMYLIRALLIVLTPLAPAHGEGIFVFPQPQFGMFPSGHTALAAMLALLAPADRPWLRWFEWAMVGVMIAGLLLARGHYSIDIAGGLLLAYFVATVRTRGGSSRRGASPTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIA0</accession>
    <name>A0A1Q2CIA0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Pyruvate, phosphate dikinase</fullName>
            <ecNumber evidence="4 7">2.7.9.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">RPIT_14345</name>
        <name evidence="15" type="ORF">SAMN05428934_11251</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1T</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1</strain>
        </source>
    </reference>
    <reference evidence="14" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10756"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.9.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 7 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.7.9.1" evidence="4 7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ15159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14345"/>
    <dbReference type="EnsemblBacteria" id="AQP45841">
        <property type="protein sequence ID" value="AQP45841"/>
        <property type="gene ID" value="RPIT_14345"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ15159">
        <property type="protein sequence ID" value="SDZ15159"/>
        <property type="gene ID" value="SAMN05428934_11251"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14345"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050242">
        <property type="term" value="F:pyruvate, phosphate dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006090">
        <property type="term" value="P:pyruvate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010121">
        <property type="entry name" value="Pyruvate_phosphate_dikinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22931">
        <property type="entry name" value="PTHR22931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000853">
        <property type="entry name" value="PPDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01828">
        <property type="entry name" value="pyru_phos_dikin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPDK_N" evidence="12">
        <location>
            <begin position="63"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="PPDK_N" evidence="12">
        <location>
            <begin position="301"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="11">
        <location>
            <begin position="421"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="13">
        <location>
            <begin position="518"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="8">
        <location>
            <position position="454"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="839"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="560"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="616"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 10">
        <location>
            <position position="752"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="773"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="774"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="775"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 10">
        <location>
            <position position="776"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000853-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000853-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000853-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="AQP45841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="SDZ15159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="884" mass="96081" checksum="C7F5D346039F9151" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIB5</accession>
    <name>A0A1Q2CIB5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DEDD_Tnp_IS110 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45795">
        <property type="protein sequence ID" value="AQP45795"/>
        <property type="gene ID" value="RPIT_14100"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14100"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="1">
        <location>
            <begin position="20"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="363" mass="39389" checksum="75AB00E965FB1C3C" modified="2017-04-12" version="1">MYKTSHTRGHRNPPSGSVVVGIDTHLDIHRAALVDAATGAPVADQQFPATPAGYLELLDWAVGHGRVSRAGVEQTGTYGAGLTAVLHAAGIEVIEINHTERGDRARHGKTDELDAYRAATAAAAGTQKGLAKHYHPAIAALRPLMVLRAHHRSSRQRAWGRVGGMLVTCPDDLADQVRGLNSAQKRARIAAWRPDLTRLHDPVNSYKLALRDLARACLDHDRAIVEIDAQLLRILTPIAPTLLAQHHVGPVTTAQLLITAGHPGRITSGDAFAKLVGVAPLPVQSGKSSRWRLSRSGDRQANSVIHRVVIGRLGTDPRSKTYIQRRVSEGKTRSEAIRALKRHVTRDLWTALQTDLNNLPHTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIB6</accession>
    <name>A0A1Q2CIB6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14410</name>
        <name evidence="3" type="ORF">SAMN05428934_11264</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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            <end position="353"/>
        </location>
    </feature>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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        <source>
            <dbReference type="EMBL" id="SDZ15386.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
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    </evidence>
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    </evidence>
    <sequence length="353" mass="38734" checksum="DA34F1C93A62A168" modified="2017-04-12" version="1">MKVFRAMAALILGAALAPLVPALDARAEVDVYSTAGHHEVNGRQWYTECEPYSQTTRCRTSIFASYVVYRDGQYVTQRDWLFNNLTYLPSPRTMWTTNPLGNNGEWTAKDGRKWRTECDTAATGRNGCRSYTEAKVVEQYNLSANVVGYRTVTKWLFNNIVRFGPITYPALQGGDALIGDPGLFECLADAAGVAHNHTAIPQSRLQNVVELDCYNRGIESLDDLGFAQLPNLEVADFSSNWLTTLDGLPYLPSLLLLDASDNELTEVGDLSSLSSLVVLAVADNHLTSVEGLSSERLQLAALDVRGNDITTVAPLADAWSLEELYVEDNPITDLDALAALIDAGLWLDVLHGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIB7</accession>
    <name>A0A1Q2CIB7_9ACTN</name>
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        </submittedName>
        <submittedName>
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        </submittedName>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
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            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
    </reference>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <text evidence="2 7">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="SAMN05428934_1126"/>
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        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="HAD-like_sf"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45800.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDZ14278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="642" mass="65586" checksum="1E4BA09002EB098C" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIC4</accession>
    <name>A0A1Q2CIC4_9ACTN</name>
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        </submittedName>
    </protein>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="AQP45862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ06946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14465"/>
    <dbReference type="EnsemblBacteria" id="AQP45862">
        <property type="protein sequence ID" value="AQP45862"/>
        <property type="gene ID" value="RPIT_14465"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ06946"/>
        <property type="gene ID" value="SAMN05428934_109123"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ06946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="141" mass="14963" checksum="0E2D477212B4B9A2" modified="2017-04-12" version="1">MTANLTLAITAGVLVAAGVYLVLERSLTRILLGILVLSNGVNLMFLVAAGRPGTPPIVDLVEEDISDPLPQAMVLTAIVITMAVAAFVLAMAYRSFQLHGHDEVADDVEDARIRELADSDVASESYEDTSFSDTGEDVVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CII8</accession>
    <name>A0A1Q2CII8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00390"/>
    <dbReference type="EnsemblBacteria" id="AQP45939">
        <property type="protein sequence ID" value="AQP45939"/>
        <property type="gene ID" value="RPIT_00390"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00390"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009597">
        <property type="entry name" value="DUF1206"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06724">
        <property type="entry name" value="DUF1206"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1206" evidence="2">
        <location>
            <begin position="23"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1206" evidence="2">
        <location>
            <begin position="104"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1206" evidence="2">
        <location>
            <begin position="190"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="262" mass="26889" checksum="66530DA0563224C4" modified="2017-04-12" version="1">MGKVEDAAKDVEDHPAASWVAAAGHVANGIVHAVIGLIAISIARGAAGEADQGGAMRAIESTPLGEISLWVVGVSMVGLGLYTLATAIGQLRDDLWQGLKDLGRMVTYFAVGVVALTYATGGTSSGEGTTESLSARLMATGWGSILLVIVGLAIVAIGVGMIVSGVRQRFMRHVDVSPKSQKWFVPLGIAGYVAKGLAVAAVGVLFVVAVWTSDPSQTGGLDGALKSFTQLPFGRVVLFGIAVGLITYGLFCLARARKAKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIM8</accession>
    <name>A0A1Q2CIM8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent zinc metalloprotease FtsH</fullName>
            <ecNumber evidence="5">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsH</name>
        <name evidence="9" type="ORF">RPIT_01565</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the central section; belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01565"/>
    <dbReference type="EnsemblBacteria" id="AQP45962">
        <property type="protein sequence ID" value="AQP45962"/>
        <property type="gene ID" value="RPIT_01565"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01565"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="8">
        <location>
            <begin position="195"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="614"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="626"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="653"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="426"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="203"/>
            <end position="210"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="425"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="429"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="501"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="679" mass="73456" checksum="7C86629245B74F31" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIR4</accession>
    <name>A0A1Q2CIR4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Metal ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_05065</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05065"/>
    <dbReference type="EnsemblBacteria" id="AQP46028">
        <property type="protein sequence ID" value="AQP46028"/>
        <property type="gene ID" value="RPIT_05065"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05065"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP46028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="327" mass="34095" checksum="27174380801FDE0B" modified="2017-04-12" version="1">MDILALPFMQRALLAALISGLIAPAIGTFIVQRRMSLLGDGLGHVAIAGVGLALMTGWAPLPLALVTSVVGAVTVELLRQRGKASGDLGLAILFYGGLASGVLMAGVAGQGAAGLSSFLFGSLTSVSPTDVLVISVLAVIILGLTIGLAPRLFAVSVDEDYSRVLGIKVNLLNLMVVVLAAVTVTISMRTVGLLLISALMVIPVATAQQSFVGFTSSFFGAMGIGAVAAVGGTVGSFYLDTATGATIVVTAIALLALSWVFGKWLRRTERFIPYVEDHGGYPHRPAESHDDEFAHSAGVKVIQHGDHLDYVHDGHRHARHGDHYDEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIT8</accession>
    <name>A0A1Q2CIT8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0749 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05715"/>
    <dbReference type="EnsemblBacteria" id="AQP46039">
        <property type="protein sequence ID" value="AQP46039"/>
        <property type="gene ID" value="RPIT_05715"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05715"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010273">
        <property type="entry name" value="DUF881"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37313">
        <property type="entry name" value="PTHR37313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05949">
        <property type="entry name" value="DUF881"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="246" mass="26081" checksum="4D2FA48F6593145F" modified="2017-04-12" version="1">MSLLTDLQADALEPGYRMNRHRPPSRARLLLAVGLVAALITVALLQTTRGAGAAETQRSELLERVSAARSRQSDLNEQVAKLDTEIRGLSELEDPAEREELQTLELAAGAAGVEGPGIVVTVSDDPGATGSQGLVLDGDLSRLVNGLWQAGAEAIAVNGRRISTLTPIRAAGAAITVDFVSLSPPYRVEAIGDPATLQARFNETAGASWWQFITMNYGLTMTIAQADGDLVLPPDPGQAVRHAKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIW0</accession>
    <name>A0A1Q2CIW0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07675"/>
    <dbReference type="EnsemblBacteria" id="AQP46078">
        <property type="protein sequence ID" value="AQP46078"/>
        <property type="gene ID" value="RPIT_07675"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07675"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="13"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="122" mass="12898" checksum="952249BDD1CEF79A" modified="2017-04-12" version="1">MTTLIDDFSLGSGERAAADAAACLFNGFADRSRLVIVQHLLLGEHRVVDLTGHLDLAQSTVSKHLACLLDCGIVQVRARGRASVYSLAHPEAILDLLSAAERLLGLTGDAVTLCPRFGRGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIX8</accession>
    <name>A0A1Q2CIX8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cation efflux family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_07670</name>
        <name evidence="12" type="ORF">SAMN05428934_12115</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000021">
        <property type="protein sequence ID" value="SDZ22858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07670"/>
    <dbReference type="EnsemblBacteria" id="AQP46079">
        <property type="protein sequence ID" value="AQP46079"/>
        <property type="gene ID" value="RPIT_07670"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ22858">
        <property type="protein sequence ID" value="SDZ22858"/>
        <property type="gene ID" value="SAMN05428934_12115"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07670"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070161">
        <property type="term" value="C:anchoring junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026765">
        <property type="entry name" value="Tmem163"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31937">
        <property type="entry name" value="PTHR31937"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0965">Cell junction</keyword>
    <keyword evidence="9" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="87"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="160"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP46079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDZ22858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="241" mass="25083" checksum="90E59261F90CE2A5" modified="2017-04-12" version="1">MSSCAQPVASPLPAERRQALGRRAQLLAGASVAYNAGEAVVAVVAGAAASSMALVGFGLDSTVEVASGLIILWQFRHRMPESREAQALRLIAVSFFALAGYVVFEAVGALVAHEPPDGSTVGVVIAALSLVIMPFLSWAQRRTGRELGSSSVVADSKQTLLCTYLSAVLLFGLVANMAWGWWWADPVAALVISAVAVREGVEAWRGEQCGCAPAPLAAHEPDSCCTSAPATVGAHREGVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ23</accession>
    <name>A0A1Q2CJ23_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">5'-3' exonuclease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Flap endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05995</name>
        <name evidence="4" type="ORF">SAMN05428934_103145</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05995"/>
    <dbReference type="EnsemblBacteria" id="AQP46045">
        <property type="protein sequence ID" value="AQP46045"/>
        <property type="gene ID" value="RPIT_05995"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68850">
        <property type="protein sequence ID" value="SDY68850"/>
        <property type="gene ID" value="SAMN05428934_103145"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05995"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033567">
        <property type="term" value="P:DNA replication, Okazaki fragment processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09898">
        <property type="entry name" value="H3TH_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020046">
        <property type="entry name" value="5-3_exonucl_a-hlix_arch_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020045">
        <property type="entry name" value="DNA_polI_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038969">
        <property type="entry name" value="FEN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42646">
        <property type="entry name" value="PTHR42646"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01367">
        <property type="entry name" value="5_3_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02739">
        <property type="entry name" value="5_3_exonuc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00475">
        <property type="entry name" value="53EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="SSF47807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="53EXOc" evidence="2">
        <location>
            <begin position="1"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY68850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="301" mass="32494" checksum="1A77C18828E37735" modified="2017-04-12" version="1">MAFDTSYLYFRAFFGVPATFRSPDGRPVNAVRGTLDFIARLVEQYSPDRFVCAWDDDWRPSWRVDLVPSYKTHRVIEGATQSVEIVDDDLTIQVPMIRDCLDALGIPVVGVAEHEADDVLASLARQHDGQSLVVTGDRDLFQLVGPDTSVVYVARGVAKHELVTPEVLATKYELAPDSYVDFAVLRGDPSDGLPGVKGIGDKSAATLVNRYPSLEAMVEAAIDAGSGMSPSMRSKLLADVDYLARAREVVTAVDTLALPTLEATPADEARIAELTETLGLGGSMGRLSALISRRAAHTGTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ25</accession>
    <name>A0A1Q2CJ25_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10065"/>
    <dbReference type="EnsemblBacteria" id="AQP46117">
        <property type="protein sequence ID" value="AQP46117"/>
        <property type="gene ID" value="RPIT_10065"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10065"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007410">
        <property type="entry name" value="PCuAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036182">
        <property type="entry name" value="PCuAC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36302">
        <property type="entry name" value="PTHR36302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04314">
        <property type="entry name" value="PCuAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110087">
        <property type="entry name" value="SSF110087"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP46117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="130" mass="14109" checksum="5E16B0E952DF22AC" modified="2017-04-12" version="1">MRTTDGAERPEMTAVFVSLTNPSEEDRVLVKADCGDVAQKVELHVMEKVDGEMVMKEAEGGLPIPAGKHEHLAPGGPHIMLMGLTRELPAGSEEVECTLTLDDGQSIEIVAPVKQFTEEQDTYHTHEADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ27</accession>
    <name>A0A1Q2CJ27_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Disulfide bond formation protein DsbA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11260"/>
    <dbReference type="EnsemblBacteria" id="AQP46136">
        <property type="protein sequence ID" value="AQP46136"/>
        <property type="gene ID" value="RPIT_11260"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11260"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DSBA" evidence="1">
        <location>
            <begin position="3"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="238" mass="25929" checksum="4DC0191C23E0BEDC" modified="2017-04-12" version="1">MDVQIWSDIACPWCYIGKRRFERALEGFEHRDEVRVTWRSYQLDPTLPQHDPRSEVEYLVQAKGLPRATVEQMVAHVGEQARGEGLEYNFDALVVANSRRAHRVLQAAKAADAADGDTRTGTLKEALLAAHFVDGEDIGDVEVLTRLAAQAGIDQAETRAAVDSATLDDAVERDIREAGEIGVRGVPFFVFAGKYGVSGAQPPEVFSQALETVWSERGQGLVTLEGADGESCGPEGCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ54</accession>
    <name>A0A1Q2CJ54_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Phosphoenolpyruvate-protein phosphotransferase</fullName>
            <ecNumber evidence="5 13">2.7.3.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Phosphotransferase system, enzyme I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">RPIT_07950</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl-[protein] + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:23880"/>
            <dbReference type="Rhea" id="RHEA-COMP:9745"/>
            <dbReference type="Rhea" id="RHEA-COMP:9746"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:64837"/>
            <dbReference type="EC" id="2.7.3.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 13 16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.7.3.9" evidence="5 13"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07950"/>
    <dbReference type="EnsemblBacteria" id="AQP46080">
        <property type="protein sequence ID" value="AQP46080"/>
        <property type="gene ID" value="RPIT_07950"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07950"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008965">
        <property type="term" value="F:phosphoenolpyruvate-protein phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024692">
        <property type="entry name" value="PTS_EI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006318">
        <property type="entry name" value="PTS_EI-like"/>
    </dbReference>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12970"/>
    <dbReference type="EnsemblBacteria" id="AQP46162">
        <property type="protein sequence ID" value="AQP46162"/>
        <property type="gene ID" value="RPIT_12970"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12970"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="23"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="123" mass="12960" checksum="FA05A2044CEA79A9" modified="2017-04-12" version="1">MSSAAGHLSDVDDCCAGAGCDLLAAQEADALASTFKALADPTRVRLLRYLAESAAGTACACHLPDALGISQPTLSFHMNKLHDAGLVAREKRGRWVHWTVRPESLAAVRGFLELPVGDQKCGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ97</accession>
    <name>A0A1Q2CJ97_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_13955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13955"/>
    <dbReference type="EnsemblBacteria" id="AQP46182">
        <property type="protein sequence ID" value="AQP46182"/>
        <property type="gene ID" value="RPIT_13955"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13955"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP46182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="255" mass="26976" checksum="FCA7445275C4E772" modified="2017-04-12" version="1">MRLAALDTVLDVEWPALTPVTFVEALTHAWSRCVVDEQARRTAPSVGALSIKSPADDDEAIRAALQRLSQDVTHRLIAAQTGRLLMFHAGAVSDPATGSTLVFVAPSGTGKTTLARLLGRTYSYLTDETVGIDPATGGVRPYPKPLSVSHGGGWRKVETSPEDLGLLPSHPEPVVSRIVLLNRNEGAPPSVATDELGTLDAIAALVPETSALNRLPRPLHAVAGLLDRAGPLLRLTYRESGDLVPLASQLIEGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJB2</accession>
    <name>A0A1Q2CJB2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_11570</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11570"/>
    <dbReference type="EnsemblBacteria" id="AQP46140">
        <property type="protein sequence ID" value="AQP46140"/>
        <property type="gene ID" value="RPIT_11570"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11570"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="9">
        <location>
            <begin position="1"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="279"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP46140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="350" mass="36873" checksum="5D928516B7831E88" modified="2017-04-12" version="1">MGGLAVTAWTVIIIALSAFFVAVEFALMAAKQHRLEERATTAAGRAALKNSHELTLLLAGSQLGITVCTLALGAITKPAVHHAITPWLERLGLPLGVADVVSFVLALIVVTFLHLVVGEMAPKSWAIAHPEDSSVLLAIPMRMFMFLARPVLKAMNASANWLVRKAGATPVDGLSASQDAAGLRQLVEHSANVGALDVRYRASLTSVLTLRDQKVRDLLPEGQELAAVGPDGTLADVQSVTRQHGHLRVLVRDGGTTVGVVHVRDTLSEPDLSRPAVELARPPVFVPAERGLAAVLAEIRQARTQIAVVTDGDREIGVITLADVLPGLMPSAIVETGLTATAPEVAPGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBE7</accession>
    <name>A0A1Q2CBE7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00145</name>
        <name evidence="2" type="ORF">SAMN05428934_10915</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ04797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43427">
        <property type="protein sequence ID" value="AQP43427"/>
        <property type="gene ID" value="RPIT_00145"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ04797">
        <property type="protein sequence ID" value="SDZ04797"/>
        <property type="gene ID" value="SAMN05428934_10915"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00145"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ04797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="120" mass="12467" checksum="574DBB322C19CD28" modified="2017-04-12" version="1">MTIPPQVGAAATWTLADSERVTATSTTVTIEVTRAECSSGMTGAIAQPVVSLGIDDIIIQVDAEPLPGNEPQNCQGNDSVQMTVSLHEPIGDRALVDAACLKGPAVRTSFCETGATRWSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBI2</accession>
    <name>A0A1Q2CBI2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sulfate adenylyltransferase</fullName>
            <ecNumber evidence="1">2.7.7.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_00015</name>
        <name evidence="9" type="ORF">SAMN05428934_10942</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.4" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00015"/>
    <dbReference type="EnsemblBacteria" id="AQP43405">
        <property type="protein sequence ID" value="AQP43405"/>
        <property type="gene ID" value="RPIT_00015"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05398">
        <property type="protein sequence ID" value="SDZ05398"/>
        <property type="gene ID" value="SAMN05428934_10942"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00015"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="CysN_ATPS"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="2"/>
            <end position="215"/>
        </location>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP43405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ05398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="437" mass="47143" checksum="F08136868AF8852E" modified="2017-04-12" version="1">MSTLLRIATAGSVDDGKSTLVGRLLYDSKAVLADQLEAVERVSLAKGLGHVDLALLTDGLRAEREQGITIDVAYRYFATAKRTFILADCPGHVQYTRNTVTGSSTADVLVLLVDARKGALEQTRRHLAVGQLLRVPHIVVAVNKIDLVDYSAQRFAEIDAEINGIADDLGVPSIRVLPVSALVGDNIVDRSEKLSWYDGPSLLELLEDLPAADATVRPFRFPVQLTIRPQDAALDPRYVEYRGYAGQVASGVVRVGDPVVVLPSGRRTTVVGIDTADGELAEAFAPQSVTLRLADDIDITRGELIAGVDAAPEPTQDLDGMVAWLAERPLRVGQKVLVKHTTRTTQAVVRDIDGRLDLDTLRPQATDSLELNDLGRVRLRLAAPIMAEAYADSRRTGSFLLVDPQSGTNLAAGMIRGDQAFSEDAAVEIDATPNWSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBJ1</accession>
    <name>A0A1Q2CBJ1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Trehalose synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00445</name>
        <name evidence="3" type="ORF">SAMN05428934_10543</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY84576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00445"/>
    <dbReference type="EnsemblBacteria" id="AQP43472">
        <property type="protein sequence ID" value="AQP43472"/>
        <property type="gene ID" value="RPIT_00445"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY84576">
        <property type="protein sequence ID" value="SDY84576"/>
        <property type="gene ID" value="SAMN05428934_10543"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00445"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
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        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
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        <property type="entry name" value="Glycoside_hydrolase_SF"/>
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    </dbReference>
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        <property type="entry name" value="O16G_dom_2"/>
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="18"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY84576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="553" mass="62939" checksum="5CC1AB708684C780" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBM7</accession>
    <name>A0A1Q2CBM7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, DeoR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_00640</name>
        <name evidence="6" type="ORF">SAMN05428934_10581</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY85581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00640"/>
    <dbReference type="EnsemblBacteria" id="AQP43507">
        <property type="protein sequence ID" value="AQP43507"/>
        <property type="gene ID" value="RPIT_00640"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY85581">
        <property type="protein sequence ID" value="SDY85581"/>
        <property type="gene ID" value="SAMN05428934_10581"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00640"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014036">
        <property type="entry name" value="DeoR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018356">
        <property type="entry name" value="Tscrpt_reg_HTH_DeoR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00455">
        <property type="entry name" value="DeoRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00037">
        <property type="entry name" value="HTHLACR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00420">
        <property type="entry name" value="HTH_DEOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00894">
        <property type="entry name" value="HTH_DEOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="4">
        <location>
            <begin position="6"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY85581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="257" mass="27502" checksum="0475BDF778E6892A" modified="2017-04-12" version="1">MERLDEGARQQAIADSVERIGRARVADLAREFAVSTVTIRKDLNALERRGVLRRVHGAATRLRASDGSAFPSRVSLCPQEKRDIARRAAQRVPDGAVIALDSSSTVYFLAKELLQRRGLTVVTYSLPTASLLLDGSTATVHLLGGVLSRSTRAVMPPADLGAPSVEIEMFFGGAHSASPELGLGEPDEAEAATKRHLALLAPQRYALLTSDKADETAAHTYLGPDEVTGIFTDPGLPADVVSRWRAAGVRVDAGRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBN5</accession>
    <name>A0A1Q2CBN5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyltransferase (GNAT) family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00705</name>
        <name evidence="3" type="ORF">SAMN05428934_10594</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY85925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43519">
        <property type="protein sequence ID" value="AQP43519"/>
        <property type="gene ID" value="RPIT_00705"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY85925">
        <property type="protein sequence ID" value="SDY85925"/>
        <property type="gene ID" value="SAMN05428934_10594"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00705"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY85925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="353" mass="39475" checksum="8560085CC9ACF120" modified="2017-04-12" version="1">MLTITEISLPETVDDDWREYQRIDRAHYHELIGGPEWDVTDEAALTAARADSEHTVRRYLARLDGEPVGNARSRVNLVDEPEHIMVFVLTLPEFRGRGIGTALAERIRADSPGFTCYQAWAECPIPGDGVATISPPSGAGALPADHPAVRLALRYGFKLGQVERVSRYDFANPLVDPAEALAEARAHAGDDYELIAWEGAAGDDILDDLATLRQRMATDVPAGDLTVVEWQWDAERMRRSDQERLLTNRMFRTVVRHRPSGTLVALNELMLDRSNPDAFVDQWDTIVLPEHRGRRLGMLVKAANLIAVKQAVPQAVSIVTWNAEENRHMLNVNEALGYYPILVEGGFELRPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBP2</accession>
    <name>A0A1Q2CBP2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NodB homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00710"/>
    <dbReference type="EnsemblBacteria" id="AQP43520">
        <property type="protein sequence ID" value="AQP43520"/>
        <property type="gene ID" value="RPIT_00710"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00710"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013021223" description="NodB homology domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="2">
        <location>
            <begin position="171"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="362" mass="39678" checksum="89C1C31DC3EEB034" modified="2017-04-12" version="1">MLRSLFGLALATLIALGGAFAPPAAADIDVYSTPGEHTINGRQWRTWCEPYSQTARCRTELVVAGKWTFNNLTYLPSPKSLWVGNPLAEPGEHTIGGRLWYTECETPATGRNGCRSYIWSGDRFVFNNLVRFGVIPSNLEELYVYRPPADPTPPTTPPTSPPITNYSMYKGPNPTSRVTLTFDDCPNSLSAFKTTAAAARDLGISLQLFPTGNCITSGKFDPAYARSMGHYVFNHSVSHPNLTTLSYDAVLRQLSAPGVVTTYGRPPYGAWNDTVKRAYDAKGMRIWLWNIDTNDWRSKTTSQVVSYVVANAKPGNSVLMHMQWNGFNGPALKAMRDGLAAKGIGVCRNQGPTEVKPASLIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBS0</accession>
    <name>A0A1Q2CBS0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_00885</name>
        <name evidence="5" type="ORF">SAMN05428934_105129</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00885"/>
    <dbReference type="EnsemblBacteria" id="AQP43552">
        <property type="protein sequence ID" value="AQP43552"/>
        <property type="gene ID" value="RPIT_00885"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86857">
        <property type="protein sequence ID" value="SDY86857"/>
        <property type="gene ID" value="SAMN05428934_105129"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00885"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544407" evidence="2">
        <location>
            <begin position="35"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="3">
        <location>
            <begin position="108"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY86857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="308" mass="31394" checksum="30698096FB4E05C0" modified="2017-04-12" version="1">MRVGRRGVLGLGVLGMAGCAPVSVPPTTPSQSTASPATTPPSQAAPSTPAPSTVAPSAVTSNQNTPSASPDPTAAVPSREDLVARYGERTARQWGIEVDGVVLRSEADAAVVTLDACGGPNGSGYDEALIEVLRSLSVPATLFLNLRWIDANPSVAAELAADPLFELANHGTAHRPLSVSGAEAYGISGTASVGEVVDEVMGGWERLAELTGSPPLWFRSGTAHVDDVAVEIVQQLGQRVVNFDVNADAGATFSASQVRRAMGEAGPGSICIGHFNRPGSGTAGGMASALPRLLDGGLAFARLRDVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBY2</accession>
    <name>A0A1Q2CBY2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">acidPPc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01285"/>
    <dbReference type="EnsemblBacteria" id="AQP43618">
        <property type="protein sequence ID" value="AQP43618"/>
        <property type="gene ID" value="RPIT_01285"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01285"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="acidPPc" evidence="2">
        <location>
            <begin position="105"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="254" mass="27842" checksum="3C93A57DF578F6FC" modified="2017-04-12" version="1">MDLEQMTPKTKRSAWLVLGIALAIALGAALLFVQLFGEVAESVADSEGVAAWDRGILDWAVASRDTWPTGLISWYSNTGGPIWQPIVTVAVVATLAWRWKDITPVVLTAIATGGSVLMTVVGKNVYGRARPPLELAVPPHESSFSFPSGHTLNATVIVGILAYLLIRHFWDRSRWVVALIVAVALVYAITMGLTRVYLGHHWFTDVLGGWALGLAWVSAIVAVHRVWRTVRRREEHAPIEEERARPQIGEPAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBY3</accession>
    <name>A0A1Q2CBY3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thymidine phosphorylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_01290</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01290"/>
    <dbReference type="EnsemblBacteria" id="AQP43619">
        <property type="protein sequence ID" value="AQP43619"/>
        <property type="gene ID" value="RPIT_01290"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01290"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004645">
        <property type="term" value="F:1,4-alpha-oligoglucan phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016154">
        <property type="term" value="F:pyrimidine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006206">
        <property type="term" value="P:pyrimidine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006213">
        <property type="term" value="P:pyrimidine nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036320">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036566">
        <property type="entry name" value="PYNP-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013102">
        <property type="entry name" value="PYNP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018090">
        <property type="entry name" value="Pyrmidine_PPas_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017872">
        <property type="entry name" value="Pyrmidine_PPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000053">
        <property type="entry name" value="Thymidine/pyrmidine_PPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10515">
        <property type="entry name" value="PTHR10515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07831">
        <property type="entry name" value="PYNP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000478">
        <property type="entry name" value="TP_PyNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00941">
        <property type="entry name" value="PYNP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="SSF47648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="SSF52418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54680">
        <property type="entry name" value="SSF54680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02644">
        <property type="entry name" value="Y_phosphoryl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00647">
        <property type="entry name" value="THYMID_PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PYNP_C" evidence="5">
        <location>
            <begin position="336"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="425" mass="44752" checksum="81B23985D3EF7E7F" modified="2017-04-12" version="1">MNMDVVDLIRIKRDGGKLSGEQIDWVIDAYTGGVVADYQMSALAMAILIRGMERDEIARWTAAMIASGERMDFSQLRWPTADKHSTGGVGDKITLPLAPLVAVFDVAVPQLSGRGLGHTGGTLDKLEAIPGWRADLTNEEMFEQLNTIGAVICAAGSGLAPADKKLYALRDTTGTVEAIPLIASSIMSKKIAEGTGALVLDVKVGSGAFMKDLDNASRLAETMVELGKDAGVNTVALLTNMDTPLGLTAGNALEVRESVEVLAGGGPADVVELTVALAREMLTAAGKPDVDPAPALQDGRAMDVWRRMIAAQDGDPDAALPVAEHQHVVNAERDGFISRMDAFGVGVAAWRLGAGRARKEDAVQAVAGVEMHAKPGDRVVAGQPLFTLHTATPERFDRAMESLEGVVDYSDQAPQVAPVILGRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC06</accession>
    <name>A0A1Q2CC06_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transcriptional regulator WhiB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">whiB</name>
        <name evidence="13" type="ORF">RPIT_01365</name>
        <name evidence="14" type="ORF">SAMN05428934_10820</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">The Fe-S cluster can be nitrosylated by nitric oxide (NO).</text>
    </comment>
    <comment type="PTM">
        <text evidence="11">Upon Fe-S cluster removal intramolecular disulfide bonds are formed.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the WhiB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01365"/>
    <dbReference type="EnsemblBacteria" id="AQP43630">
        <property type="protein sequence ID" value="AQP43630"/>
        <property type="gene ID" value="RPIT_01365"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01283">
        <property type="protein sequence ID" value="SDZ01283"/>
        <property type="gene ID" value="SAMN05428934_10820"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01365"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035731">
        <property type="term" value="F:dinitrosyl-iron complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01479">
        <property type="entry name" value="WhiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034768">
        <property type="entry name" value="4FE4S_WBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003482">
        <property type="entry name" value="Whib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38839">
        <property type="entry name" value="PTHR38839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02467">
        <property type="entry name" value="Whib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51674">
        <property type="entry name" value="4FE4S_WBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 11" id="KW-0408">Iron</keyword>
    <keyword evidence="6 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 11" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="4Fe-4S Wbl-type" evidence="12">
        <location>
            <begin position="14"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP43630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDZ01283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="103" mass="11585" checksum="ACA7242DBEE2FFE4" modified="2017-04-12" version="1">MSLAEVSEWTLRAKCRDMADALFPEGKDQKRARSVCAGCPVRSECLAEALDNRIEWGVWGGMTERERRALLRSRPDITSWHDVLINYNDEGDASIAVLPAGRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC33</accession>
    <name>A0A1Q2CC33_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Thiamine transport system ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_01625</name>
        <name evidence="9" type="ORF">SAMN05428934_10873</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01625"/>
    <dbReference type="EnsemblBacteria" id="AQP43669">
        <property type="protein sequence ID" value="AQP43669"/>
        <property type="gene ID" value="RPIT_01625"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02312">
        <property type="protein sequence ID" value="SDZ02312"/>
        <property type="gene ID" value="SAMN05428934_10873"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01625"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015408">
        <property type="term" value="F:ABC-type ferric iron transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03259">
        <property type="entry name" value="ABC_Carb_Solutes_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015853">
        <property type="entry name" value="ABC_transpr_FbpC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="4"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP43669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ02312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="323" mass="34399" checksum="8F3CFC0246ECF33A" modified="2017-04-12" version="1">MVGLEVRDAVVRYGATTAVDHVSLQVTPGAVVALLGPSGSGKSTLLRAIAGLEPLVSGAVLWDGTDLARVKVHKRNFGMVFQDAQLFPTMTVGRNIAYGLGSLGRAAQRERVAEMLDLIGLPGFESRRVTELSGGQAQRIALARSLAPSPRLLLLDEPLSALDTGLRRRLADDLARILRATHTTAIHVTHDHQEAYTVADTVAVLQEGRLLQEADPDALRRTPASREVAAFLGFRAFVTQQQARVLLWDGTLPVGTVLGIGPGSLVPDQAGVEVPILDQGFTVDDVEVGVRLPDGQRAVVSVPERLDSSTMRIRLIGGAVTPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC34</accession>
    <name>A0A1Q2CC34_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase</fullName>
            <ecNumber evidence="2">2.7.6.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_01585</name>
        <name evidence="10" type="ORF">SAMN05428934_10865</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.3" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01585"/>
    <dbReference type="EnsemblBacteria" id="AQP43662">
        <property type="protein sequence ID" value="AQP43662"/>
        <property type="gene ID" value="RPIT_01585"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02165">
        <property type="protein sequence ID" value="SDZ02165"/>
        <property type="gene ID" value="SAMN05428934_10865"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01585"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003848">
        <property type="term" value="F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00483">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="SSF55083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01498">
        <property type="entry name" value="folK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00794">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPPK" evidence="8">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP43662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ02165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="187" mass="20618" checksum="48BCE5E58AE5DA79" modified="2017-04-12" version="1">MSNGPFDIDVDTLGNLRPISKVVLSLGSNMGDSPVILQEAVDYLADTPDLIIVDVSPVYQTKPFGDIQEQDDFLNLVVVAESTLEPLTILDRAQAIEENFGRTREERHGPRTLDIDIIMVGKRISEDNIELPHPAAHERAFVLVPWHDIDPNGEIAGHGRIADLLDEVDTSTVTLREDVVIQANTGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC48</accession>
    <name>A0A1Q2CC48_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01695"/>
    <dbReference type="EnsemblBacteria" id="AQP43681">
        <property type="protein sequence ID" value="AQP43681"/>
        <property type="gene ID" value="RPIT_01695"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01695"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008554">
        <property type="entry name" value="Glutaredoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05768">
        <property type="entry name" value="Glrx-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="104" mass="11555" checksum="02D0F8841160BE77" modified="2017-04-12" version="1">MTPPSRVVLLTRAGCHLCVEAEATLRRTCEDLGVAWRALDIDSEPDLRAGFTDHVPVTFVDRQLLSYWFLDEDALRAALSQPAPSRRTTSGFPPSTSSPERMQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC51</accession>
    <name>A0A1Q2CC51_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1713 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_002550589.1">
        <property type="nucleotide sequence ID" value="NZ_FNPU01000008.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43680">
        <property type="protein sequence ID" value="AQP43680"/>
        <property type="gene ID" value="RPIT_01690"/>
    </dbReference>
    <dbReference type="GeneID" id="31538823"/>
    <dbReference type="GeneID" id="66620330"/>
    <dbReference type="KEGG" id="tfl:RPIT_01690"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013177">
        <property type="entry name" value="COX24_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08213">
        <property type="entry name" value="DUF1713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01155">
        <property type="entry name" value="DUF1713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1713" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="33" mass="4073" checksum="4256B042E26371E7" modified="2017-04-12" version="1">MGSVIKKRRKRMAKKKHRKLLKKTRIQRRRAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCB9</accession>
    <name>A0A1Q2CCB9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitrate reductase molybdenum cofactor assembly chaperone</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Respiratory nitrate reductase chaperone NarJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02140</name>
        <name evidence="3" type="ORF">SAMN05428934_10126</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY23077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02140"/>
    <dbReference type="EnsemblBacteria" id="AQP43759">
        <property type="protein sequence ID" value="AQP43759"/>
        <property type="gene ID" value="RPIT_02140"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY23077">
        <property type="protein sequence ID" value="SDY23077"/>
        <property type="gene ID" value="SAMN05428934_10126"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02140"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020945">
        <property type="entry name" value="DMSO/NO3_reduct_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003765">
        <property type="entry name" value="NO3_reductase_chaperone_NarJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036411">
        <property type="entry name" value="TorD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43680">
        <property type="entry name" value="PTHR43680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02613">
        <property type="entry name" value="Nitrate_red_del"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89155">
        <property type="entry name" value="SSF89155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00684">
        <property type="entry name" value="narJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY23077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="207" mass="23067" checksum="E7B879BB5682AEE3" modified="2017-04-12" version="1">MSNDTQICFQAAGLLLSYPDEQLLSTLDLVEDAVAATPSAPLFAPVLAHLRAKPLRELQEFHVQEFDLSRRHALHLTYWTDGDTRRRGEVLAAIKQTYRESGLLVNLDGELPDYLPMVLEFAARGDQERGLGLLNSYRASLELLRLGLRKDKLPHEGVVEAVCRCLPGPMARDRADVQTLYGAMFVDAPPIEQVGLETYQIQTGRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCE0</accession>
    <name>A0A1Q2CCE0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase InsO and inactivated derivatives</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02260</name>
        <name evidence="3" type="ORF">SAMN05428934_10151</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY23822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43782">
        <property type="protein sequence ID" value="AQP43782"/>
        <property type="gene ID" value="RPIT_02260"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY23822">
        <property type="protein sequence ID" value="SDY23822"/>
        <property type="gene ID" value="SAMN05428934_10151"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02260"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025948">
        <property type="entry name" value="HTH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13276">
        <property type="entry name" value="HTH_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13333">
        <property type="entry name" value="rve_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="114"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY23822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="297" mass="32679" checksum="E3348391607279A0" modified="2017-04-12" version="1">MTDKFTLIHAEKATHTVELMTRLLDVSRAGYYAWAKRGDTPGPAATRRAEVTAAVIESHAASNGVNGHRRVLADLTADGVPASAGMVRSIMRQAGIAGIQPRTKKRTTIPADDAEQRPDLVKRDFTSDTAGSKLVGDITYLRTGEGWLYLATVIDLHSRMVVGWAMAEHMRTELISAALRMAHTHGHLAPGAVFHSDRGSQYTSADYAALAGQFGVQLSVGRTGSCHDNAVAESWFSMLKNEMYYRHRFATRAQARLHVMQYIEVFYNRRRRHSTLDYQTPAAVHAAARHHQTAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCF6</accession>
    <name>A0A1Q2CCF6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyclic pyranopterin monophosphate synthase</fullName>
            <ecNumber evidence="3">4.6.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_02340</name>
        <name evidence="7" type="ORF">SAMN05428934_10168</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:49580"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59648"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.6.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.17" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY24321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02340"/>
    <dbReference type="EnsemblBacteria" id="AQP43798">
        <property type="protein sequence ID" value="AQP43798"/>
        <property type="gene ID" value="RPIT_02340"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY24321">
        <property type="protein sequence ID" value="SDY24321"/>
        <property type="gene ID" value="SAMN05428934_10168"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02340"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061799">
        <property type="term" value="F:cyclic pyranopterin monophosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023045">
        <property type="entry name" value="Mo_CF_biosynth-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036522">
        <property type="entry name" value="MoaC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002820">
        <property type="entry name" value="Mopterin_CF_biosynth-C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01967">
        <property type="entry name" value="MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55040">
        <property type="entry name" value="SSF55040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00581">
        <property type="entry name" value="moaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoaC" evidence="5">
        <location>
            <begin position="14"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY24321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="154" mass="15764" checksum="4C3D531C9735F190" modified="2017-04-12" version="1">MGFTHLDSAGHARMVDVTAKQPTVRSATAVASVRCSQDVVSALREGTVPKGDVLAVARVAGIAAAKKVPDLLPLAHVIGVHGVTVDLDIVDTGIDITATVRTADRTGVEMEALTAATVAALAVVDMIKGVDKLSEIVSAKVVAKSGGRSGDWTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCF7</accession>
    <name>A0A1Q2CCF7_9ACTN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_02280</name>
        <name evidence="2" type="ORF">SAMN05428934_10155</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY23941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43786">
        <property type="protein sequence ID" value="AQP43786"/>
        <property type="gene ID" value="RPIT_02280"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY23941">
        <property type="protein sequence ID" value="SDY23941"/>
        <property type="gene ID" value="SAMN05428934_10155"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02280"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY23941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="118" mass="13482" checksum="9F0EF042EEE7B9C4" modified="2017-04-12" version="1">MQILGDRTRQLPAPPHVVFTSLTHPGLPCARPWLVLLDDEVPPVILSSHEPHRVQWSSLWPSRPNDLVDLELSPKDGGTLLRFILSTPDEEPDASKLGHMRRRRHHLLFADLRFSYGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCJ1</accession>
    <name>A0A1Q2CCJ1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_02605</name>
        <name evidence="2" type="ORF">SAMN05428934_101121</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY25910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43843">
        <property type="protein sequence ID" value="AQP43843"/>
        <property type="gene ID" value="RPIT_02605"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY25910">
        <property type="protein sequence ID" value="SDY25910"/>
        <property type="gene ID" value="SAMN05428934_101121"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02605"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036069">
        <property type="entry name" value="DUF34/NIF3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102705">
        <property type="entry name" value="SSF102705"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY25910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="106" mass="11228" checksum="CE9DA9E02D36188D" modified="2017-04-12" version="1">MIVIVVFSPRSHADEVRAALAAAGAGTLGNYTACSFSASGEGRFRPEEGAEPYLGEPGRPEVVDEVRIECVCDDALAKGAVEAMLAAHPYEEPAYHCYRALTLGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCK7</accession>
    <name>A0A1Q2CCK7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Patatin-like phospholipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_02535</name>
        <name evidence="6" type="ORF">SAMN05428934_101107</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY25463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02535"/>
    <dbReference type="EnsemblBacteria" id="AQP43831">
        <property type="protein sequence ID" value="AQP43831"/>
        <property type="gene ID" value="RPIT_02535"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY25463">
        <property type="protein sequence ID" value="SDY25463"/>
        <property type="gene ID" value="SAMN05428934_101107"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02535"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="4">
        <location>
            <begin position="23"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="119"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="56"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="293"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY25463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="490" mass="54232" checksum="66F16FB97BD5DFE3" modified="2017-04-12" version="1">MAVNRRFTIPFLTQDPRDETVACVLSGGGSRASFQLGALDYLYRHDESFSPTVFVGTSAGSIVASVLAQDARRDQQHAYLLRLAELWSGMTTPADMFTPRPWYERLQEEGPGWLTMVNPPRPAPKPRTPLLPFLRQPDQAPDPEARSETAPSPLELALLPDEEVRSEWSLAALSGLAGNVGRLPRIGSDLNTIWQGLERTRSLYRPGPVLGRLLEPETFDPARVRLSGSTLRVAMVALESGELRYMTERGTLVDRQNRPLGNTAHDLTVGVLASCSIPAVFRPVPIGDETYVDGGARENLPAELALNHLGVGRTYVISSQSLGVQRRASMANADLFTVVMRSTEILIDEAGRDELAYAEATGATVVYPELGVHDAMVVHPGLIAINMAYGWFRAAEQHLELDDRAAAQHRRIIDLRIRILDLEQRFLGLESPTSRDLMVLRSAKVELRDAVRGAHTTPLPDGAEQWWTQWERHPEPPTMQPPWMPMPAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCL2</accession>
    <name>A0A1Q2CCL2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Phospholipase_D-nuclease N-terminal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_02565</name>
        <name evidence="10" type="ORF">SAMN05428934_101113</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY25650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43837">
        <property type="protein sequence ID" value="AQP43837"/>
        <property type="gene ID" value="RPIT_02565"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY25650">
        <property type="protein sequence ID" value="SDY25650"/>
        <property type="gene ID" value="SAMN05428934_101113"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02565"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027379">
        <property type="entry name" value="CLS_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13396">
        <property type="entry name" value="PLDc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="PLDc_N" evidence="8">
        <location>
            <begin position="13"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="67"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP43837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY25650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="83" mass="9346" checksum="FD3AB4703A11DA91" modified="2017-04-12" version="1">MARVLLIIAIVMLTVYCVVEVAQARGYKVRLMPRWLWAFAVVCLPVLGPVAWLTLGRPIKSNPSIDRGPRAPDDDEDFLRGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCN9</accession>
    <name>A0A1Q2CCN9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADH-quinone oxidoreductase subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_02745</name>
        <name evidence="4" type="ORF">SAMN05428934_101149</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY26727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02745"/>
    <dbReference type="EnsemblBacteria" id="AQP43866">
        <property type="protein sequence ID" value="AQP43866"/>
        <property type="gene ID" value="RPIT_02745"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY26727">
        <property type="protein sequence ID" value="SDY26727"/>
        <property type="gene ID" value="SAMN05428934_101149"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02745"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037232">
        <property type="entry name" value="NADH_quin_OxRdtase_su_C/D-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001268">
        <property type="entry name" value="NADH_UbQ_OxRdtase_30kDa_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00329">
        <property type="entry name" value="Complex1_30kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143243">
        <property type="entry name" value="SSF143243"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex1_30kDa" evidence="2">
        <location>
            <begin position="5"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY26727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="171" mass="18618" checksum="1005C28ACFDB25B8" modified="2017-04-12" version="1">MPVTWRAEVEAAREAGFTFLANLTAVDEVGHSDHIRVLLWLERPDDGEPARIEALVDRDRPSLPDIADIFPGAAWLQRQVHDFFGVEFNGGDNRPLIHHGGGAPLRKDVLLEQRQEVHWPGALEPGESDAAPGRRKLVPPGVPDPSLLADPAATAADIALSATGARVRRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCP1</accession>
    <name>A0A1Q2CCP1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">DNA-directed RNA polymerase subunit beta</fullName>
            <shortName evidence="6">RNAP subunit beta</shortName>
            <ecNumber evidence="6 8">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">RNA polymerase subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Transcriptase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpoB</name>
        <name evidence="15" type="ORF">RPIT_02915</name>
        <name evidence="16" type="ORF">SAMN05428934_101184</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1T</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1</strain>
        </source>
    </reference>
    <reference evidence="15" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6 8">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="6 8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY27742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02915"/>
    <dbReference type="EnsemblBacteria" id="AQP43893">
        <property type="protein sequence ID" value="AQP43893"/>
        <property type="gene ID" value="RPIT_02915"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY27742">
        <property type="protein sequence ID" value="SDY27742"/>
        <property type="gene ID" value="SAMN05428934_101184"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02915"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01321">
        <property type="entry name" value="RNApol_bact_RpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042107">
        <property type="entry name" value="DNA-dir_RNA_pol_bsu_ext_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019462">
        <property type="entry name" value="DNA-dir_RNA_pol_bsu_external_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010243">
        <property type="entry name" value="RNA_pol_bsu_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="PTHR20856"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10385">
        <property type="entry name" value="RNA_pol_Rpb2_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02013">
        <property type="entry name" value="rpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA_pol_Rpb2_1" evidence="12">
        <location>
            <begin position="49"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_2" evidence="11">
        <location>
            <begin position="182"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_3" evidence="13">
        <location>
            <begin position="432"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_45" evidence="14">
        <location>
            <begin position="510"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_6" evidence="9">
        <location>
            <begin position="638"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_7" evidence="10">
        <location>
            <begin position="1057"/>
            <end position="1131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF10385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="AQP43893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="SDY27742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="1172" mass="130329" checksum="93A529B7F5EBB1BF" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCP9</accession>
    <name>A0A1Q2CCP9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">UDP-N-acetylenolpyruvoylglucosamine reductase</fullName>
            <ecNumber evidence="17">1.3.1.98</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">UDP-N-acetylmuramate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">murB</name>
        <name evidence="19" type="ORF">RPIT_02815</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 17">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>NADP(+) + UDP-N-acetyl-alpha-D-muramate = H(+) + NADPH + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:12248"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="EC" id="1.3.1.98"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 17">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 17">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 17">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 17">Belongs to the MurB family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.98" evidence="17"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02815"/>
    <dbReference type="EnsemblBacteria" id="AQP43876">
        <property type="protein sequence ID" value="AQP43876"/>
        <property type="gene ID" value="RPIT_02815"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02815"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008762">
        <property type="term" value="F:UDP-N-acetylmuramate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.78.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00037">
        <property type="entry name" value="MurB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003170">
        <property type="entry name" value="MurB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011601">
        <property type="entry name" value="MurB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036635">
        <property type="entry name" value="MurB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21071">
        <property type="entry name" value="PTHR21071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02873">
        <property type="entry name" value="MurB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56194">
        <property type="entry name" value="SSF56194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15 17" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8 17" id="KW-0132">Cell division</keyword>
    <keyword evidence="12 17" id="KW-0133">Cell shape</keyword>
    <keyword evidence="16 17" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7 17" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 17" id="KW-0274">FAD</keyword>
    <keyword evidence="9 17" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11 17" id="KW-0521">NADP</keyword>
    <keyword evidence="14 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13 17" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="18">
        <location>
            <begin position="15"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="active site" evidence="17">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="17">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <feature type="active site" evidence="17">
        <location>
            <position position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00010485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="AQP43876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="347" mass="36357" checksum="A26D572F278C0A0A" modified="2017-04-12" version="1">MPDSTLLADHTTLRVGGPAGRFVVATTETELVETVTDCDSRGEPVLVLGGGSNLLVSDDGFPGTVVRVAMTGLQADVSACGGASVKVAAGENWDTFVAYAVEQEWTGIEMLSGIPGLVGATPIQNVGAYGSDVSHTIDSVRTWDRLERRQRTFALADCGFGYRTSRFKREPGRYLVLEVGFQFQLGALGSPVAYPELARHLGVELGTRAPARAIREAVLSIRAGKGMVLSPTDPDTWSAGSFFTNPILSADEAAALPADAPRFPAEGGLVKTSAAWLIQHAGFQKGFGTERASLSTKHVLALTNRGGASAADLAELAGQVQRGVADRFGIQLVPEVNLIGLTTSTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCR1</accession>
    <name>A0A1Q2CCR1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Beta-galactosidase</fullName>
            <ecNumber evidence="2">3.2.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_03030</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03030"/>
    <dbReference type="EnsemblBacteria" id="AQP43913">
        <property type="protein sequence ID" value="AQP43913"/>
        <property type="gene ID" value="RPIT_03030"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03030"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009341">
        <property type="term" value="C:beta-galactosidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004199">
        <property type="entry name" value="B-gal_small/dom_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032312">
        <property type="entry name" value="LacZ_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02929">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16353">
        <property type="entry name" value="DUF4981"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01038">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="SSF49303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bgal_small_N" evidence="5">
        <location>
            <begin position="113"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="397" mass="42899" checksum="10EFEA2D24A62783" modified="2017-04-12" version="1">MATSIENRRHDGDTSDLRILWRDEVDGREVGSGVVEARPVEAGELIAVSMPSYQVPESGELWRTVEAVTAAGSAWADEGHVVASQQLLLAEAPVPPRRPSVTEIPTEVAGEYHLGGARFDAHTGDLVELGGRPIGGPRLELWRAPIENDLLAFSNSYVAVEPTASRGVGAPAPSWADQWRAAGIDRLQRRVVSVTPGPGSLSVVHRYAPAASREAVVVELAWTWDGASLILEGSAVPSKGWTGTWPRIGLHFRLPEGLSRAEWFGTGPAENYADSNVAARVGRFASNVSDLIVDYAVPQESGLRMQLRELQLPDIDLEIRAQRAGGDLPGFALRAHDAHEVTGAAHPYELPESTATHLYLDVAQHGLGSRSCGPDVRPEYQLRPRAASWSLALRLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCS4</accession>
    <name>A0A1Q2CCS4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_02615</name>
        <name evidence="4" type="ORF">SAMN05428934_101123</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY25970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02615"/>
    <dbReference type="EnsemblBacteria" id="AQP43845">
        <property type="protein sequence ID" value="AQP43845"/>
        <property type="gene ID" value="RPIT_02615"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY25970">
        <property type="protein sequence ID" value="SDY25970"/>
        <property type="gene ID" value="SAMN05428934_101123"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02615"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046264">
        <property type="entry name" value="DUF6297"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19814">
        <property type="entry name" value="DUF6297"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="471"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="519"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY25970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="540" mass="56884" checksum="940721ABFAEAA580" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCX7</accession>
    <name>A0A1Q2CCX7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Carbohydrate ABC transporter membrane protein 2, CUT1 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_03250</name>
        <name evidence="7" type="ORF">SAMN05428934_101251</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03250"/>
    <dbReference type="EnsemblBacteria" id="AQP43951">
        <property type="protein sequence ID" value="AQP43951"/>
        <property type="gene ID" value="RPIT_03250"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29843">
        <property type="protein sequence ID" value="SDY29843"/>
        <property type="gene ID" value="SAMN05428934_101251"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03250"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="63"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY29843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="269" mass="28817" checksum="E9C7EEE26E28AC75" modified="2017-04-12" version="1">MRVGTGEKVLNYVILALFAAYALFPIITIAVTALGPQNGVTEPGPHFYNIADAWEIGGFAGALTRSLMVAALVVSVALTLSVLAGYAFGTMRFKGSTFLFYLFLLGLMVPAEAIVIPLFFDLRTVGLTDTIWAVALPQIAQSVAFGTFWMRAQFRALPPNLVEAAAIDGVSGMRTLSKVVVPPSLPSIATVAVLMFMWTWNEFLIPLIMSPGAQWRTAPLGLAIFKGQYTADNALIAAAGVIIAAPIIVVFLLLQRYFINGMLEGAAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCZ3</accession>
    <name>A0A1Q2CCZ3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Methionine aminopeptidase</fullName>
            <shortName evidence="2">MAP</shortName>
            <shortName evidence="2">MetAP</shortName>
            <ecNumber evidence="2 3">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">map</name>
        <name evidence="5" type="ORF">RPIT_03490</name>
        <name evidence="6" type="ORF">SAMN05428934_101298</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2 3">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="2 3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY31289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03490"/>
    <dbReference type="EnsemblBacteria" id="AQP43992">
        <property type="protein sequence ID" value="AQP43992"/>
        <property type="gene ID" value="RPIT_03490"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY31289">
        <property type="protein sequence ID" value="SDY31289"/>
        <property type="gene ID" value="SAMN05428934_101298"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03490"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070084">
        <property type="term" value="P:protein initiator methionine removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="47"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY31289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="291" mass="31960" checksum="F1670D5AA4A500B9" modified="2017-04-12" version="1">MTVTPITPFDITPLRDVPRTIRRPEYVGRPAPKPYTGSDVQTSEIIEKMRVAGRIAADAMHEAGKAIAPGVTTDQLDAVAHQYMLDHGAYPSALGYRGFPKSVCTSVNEVVCHGIPDLRPLEDGDLVKIDVTAYKDGVHGDNCYTFFCGDVDEESRLLTERTQEALNRAIKAVRPGRPVSVIGRVIEAYAKRFGYGVIRDYTGHGVHTAFHSGLVILHYDEPRMDTLMQPGMTFTIEPMLTLGGHDTDVWDDDWTVITTDGSRVAQFEHSLVVTNDGAEILTLPSSPPPPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD02</accession>
    <name>A0A1Q2CD02_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized membrane protein YccF, DUF307 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_03435</name>
        <name evidence="4" type="ORF">SAMN05428934_101287</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43984">
        <property type="protein sequence ID" value="AQP43984"/>
        <property type="gene ID" value="RPIT_03435"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30968">
        <property type="protein sequence ID" value="SDY30968"/>
        <property type="gene ID" value="SAMN05428934_101287"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03435"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031308">
        <property type="entry name" value="UCP028777"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005185">
        <property type="entry name" value="YccF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03733">
        <property type="entry name" value="YccF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028777">
        <property type="entry name" value="UCP028777"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="YccF" evidence="2">
        <location>
            <begin position="4"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="YccF" evidence="2">
        <location>
            <begin position="68"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY30968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="127" mass="13647" checksum="FB032AFEBF13BCAA" modified="2017-04-12" version="1">MRTLLNVIWVIFGGFWLALGYFVAGVLACLLIVTIPVGIASFRMARYVLWPFGKTVVKKEGAGAGSAIMNGIWFLVAGWWLAVLHVATALAQSLTIVGLANAVVSIKMIPVTCFPFGKRITDSGSFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD25</accession>
    <name>A0A1Q2CD25_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NitT/TauT family transport system substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03520</name>
        <name evidence="3" type="ORF">SAMN05428934_101305</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY31477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03520"/>
    <dbReference type="EnsemblBacteria" id="AQP43997">
        <property type="protein sequence ID" value="AQP43997"/>
        <property type="gene ID" value="RPIT_03520"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY31477">
        <property type="protein sequence ID" value="SDY31477"/>
        <property type="gene ID" value="SAMN05428934_101305"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03520"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027939">
        <property type="entry name" value="NMT1/THI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31528">
        <property type="entry name" value="PTHR31528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10518">
        <property type="entry name" value="TAT_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NMT1" evidence="1">
        <location>
            <begin position="42"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY31477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="327" mass="33977" checksum="58543FC26F5B0BC8" modified="2017-04-12" version="1">MINRRNFIRGAAAVGIASAVGCAPSRPSTSEQLTVGLTYIPNVQFSAFYVGVAEGIFAKHGLDVKLRHHGQQEDLFGAILRGEEDVVFASADEGVVAAAQGNDLRTFATSYQRYPIEVVGDARAAGVDPSGGLEMLAGRSLGIPGHFGSSYYAALVAMHNAGLSEDEVQLTDIGFTTVAAIAGRKVDFAMAFSNNEVIQLEAQGIPLAVLPIQDPSAPSLVGPGLLTRGTTLGDDVLAALAAAMKESEEAVIADPELALDATAREVPALADPAQKESAEKVLLATTELWAPNGEVSVAVDAAAMDRMATLLTDVGIIEAPPSDFYIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD61</accession>
    <name>A0A1Q2CD61_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03785"/>
    <dbReference type="EnsemblBacteria" id="AQP44044">
        <property type="protein sequence ID" value="AQP44044"/>
        <property type="gene ID" value="RPIT_03785"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03785"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="382" mass="41051" checksum="44D6000A0E0E8346" modified="2017-04-12" version="1">MWFRERHDMLGRVYTVVAVARSLLAAHAVAVNLAIVMPRAHNPAAVVAVSVAIIVWHTLITLRMRKAHRRTPAAHLADLGVTLAITLTTGLVVRPGGAPLSLAGYWIGGCAAYAAIFRSTRWGVAFAAAVAAVLVFTPGHFTMERLGSSFVILLFTACLGVLITQFRATLREQEQDRLRSAALAERERLSRIVHDGALQVLALVEREGPSLGPRGARLAVLARESEAQLRTLLQDREIVGLEHSEVVDLAAVLDKYQSARVTVSTMASGVMASRSLVDEVEAAVAEILTNVDLHAGADAQAWILLDQEECDEVILWVRDNGVGMSAELVRQAAESGRLGIRDSVVGRIGAVGGTATLRSSPGAGAEWELRVPINGERQRHSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD66</accession>
    <name>A0A1Q2CD66_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03750</name>
        <name evidence="3" type="ORF">SAMN05428934_101352</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
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    <reference evidence="2" key="3">
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            </authorList>
        </citation>
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            <strain evidence="2">RP1T</strain>
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    </reference>
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    </dbReference>
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        <property type="gene ID" value="SAMN05428934_101352"/>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="315" mass="33215" checksum="A477BE209D017965" modified="2017-04-12" version="1">MGKSQELKKAAADTASAAADYGAVALKEGLERAQHLLNEAREQAGPYLHDAKVRSASFASRRLDDIEPHLKDALDRVTPAVDAVRGKVADDLLPKLQDALHHAAEHPALAEASKRGSAAVRALKGEVEPVRKPSKLKKVGKLLAVGAILAGAVAAVRHFLAPKDDGWTAHEPSKAYQNNNDTFSTAAKFAADTATTDEVAPDDEAKAEDMTSEGGPSATETEPIAQPGEVGAGVDGAPVEGDSVDSVEAEATEEKHYGDGSYVGDNPPEGFNIKGNERSKKYHVEGTGGYERTIAEVWFNSEEAAEAAGFTRAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD88</accession>
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
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    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    </dbReference>
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            <end position="50"/>
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            <end position="171"/>
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            <begin position="141"/>
            <end position="157"/>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44079.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="171" mass="17387" checksum="DAC0ADF857E29B47" modified="2017-04-12" version="1">MSAQQIAQDVQPRPRLRVVPAAPTAAVSTLGFVGIVLSLLAAGLALVMIVTTSVGAQSKELASLRTTSTQLGYRAAALESNLQRASSANALALRATELGMVPNPYPAFVNLADGTVTGEPTKATGDEMPFLRGIAPSPAEPTVPIITPAPEPPPAVADPALVAAGSTEEQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD92</accession>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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                <person name="Schumann P."/>
                <person name="Lal R."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">RP1T</strain>
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    <reference evidence="4 6" key="2">
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                <person name="de Groot N.N."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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        <property type="gene ID" value="RPIT_03960"/>
    </dbReference>
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        <property type="gene ID" value="SAMN05428934_101396"/>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="130" mass="14215" checksum="C079E307872B5C37" modified="2017-04-12" version="1">MALSEQERKLLEQLEASLMADDPKLHDTLSGSSSIRVHRRRATLAGLGFIAGVVVLLVGVQIHPAISIAGFVLMLVGALVGINSWQRVGDDSDQPARPRFTAPSGGPAQTSQDFMDKLEERWRRRQQGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDA4</accession>
    <name>A0A1Q2CDA4_9ACTN</name>
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Schumann P."/>
                <person name="Lal R."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="protein sequence ID" value="SDY33574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="protein sequence ID" value="SDY33574"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Transposase_DDE"/>
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    <proteinExistence type="predicted"/>
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            <begin position="4"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY33574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="134" mass="14684" checksum="F06A8B05455D3F3B" modified="2017-04-12" version="1">MIDAYQAPDPVEGKKIMTRLVTSLQSGVPAGLDELRSLGQTMKRRRDDILAFFDHPGTSNGPTEAINGLLEHLRGTARGFRSIVNYVARCLLDAGGFRPLIHSLCEEPVMQPEGRGRRIDDRERVPPETGSGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDG8</accession>
    <name>A0A1Q2CDG8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fe-S cluster assembly protein SufB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Iron-regulated ABC transporter membrane component SufB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_04340</name>
        <name evidence="4" type="ORF">SAMN05428934_101473</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0051 (ycf24) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY36225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04340"/>
    <dbReference type="EnsemblBacteria" id="AQP44137">
        <property type="protein sequence ID" value="AQP44137"/>
        <property type="gene ID" value="RPIT_04340"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY36225">
        <property type="protein sequence ID" value="SDY36225"/>
        <property type="gene ID" value="SAMN05428934_101473"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04340"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010231">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045595">
        <property type="entry name" value="SufBD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19295">
        <property type="entry name" value="SufBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01980">
        <property type="entry name" value="sufB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufBD_N" evidence="2">
        <location>
            <begin position="143"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY36225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="480" mass="53335" checksum="622BE90AFC2D8292" modified="2017-04-12" version="1">MTQTAPKAPGLGATQDEHLEALSKYEWGWHDSDTAGSTAQRGLSEAVVRNISALKDEPQWMLDLRLKGLKMFDKKPMPTWGADLSGIDFDNIKYFVRSTERQAQTWDDLPDDIKNTYDRLGIPEAEKARLVSGVAAQYESEVVYHKINEELERQGVIFLDTDTALKEHPELFQEYFGTVIPVGDNKFASLNTSVWSGGSFIYVPKGVNVTIPLQAYFRINTENMGQFERTLIIVDEGAYVHYVEGCTAPIYSSDSLHSAVVEIIVKKNARCRYTTIQNWSTNVYNLVTKRATCEEGATMEWIDGNIGSKVTMKYPAVYLMGEHARGETLSIAFAGEGQHQDAGSKMVHAAPNTSSSIVSKSVARGGGRSSYRGLVKVEPGARHSASSVMCDALLVDTISRSDTYPYVDVREEDVSMAHEATVSKVSEDQLFYLMSRGMEELEAMAMIVRGFVEPIARELPMEYALELNRLIELQMEGAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDI1</accession>
    <name>A0A1Q2CDI1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YlxR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04595"/>
    <dbReference type="EnsemblBacteria" id="AQP44182">
        <property type="protein sequence ID" value="AQP44182"/>
        <property type="gene ID" value="RPIT_04595"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04595"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007393">
        <property type="entry name" value="DUF448"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035931">
        <property type="entry name" value="YlxR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04296">
        <property type="entry name" value="YlxR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64376">
        <property type="entry name" value="SSF64376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YlxR" evidence="1">
        <location>
            <begin position="5"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="87" mass="9478" checksum="A4422F9D65DE26E7" modified="2017-04-12" version="1">MSPIRTCIACRERAEQGSLIRLVRVGDRIVDATEPRLAGRGAYLHRDCFDLALARHAFRRTFGPGAVVEGLFSGGESHEVEASPAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDK6</accession>
    <name>A0A1Q2CDK6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Riboflavin biosynthesis protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="11">Riboflavin kinase</fullName>
                <ecNumber evidence="11">2.7.1.26</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="11">Flavokinase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="11">FMN adenylyltransferase</fullName>
                <ecNumber evidence="11">2.7.7.2</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="11">FAD pyrophosphorylase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="11">FAD synthase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="13" type="ORF">RPIT_04615</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 11">
            <text>ATP + FMN + H(+) = diphosphate + FAD</text>
            <dbReference type="Rhea" id="RHEA:17237"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="2.7.7.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + riboflavin = ADP + FMN + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14357"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57986"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 11">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ribF family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="11"/>
    <dbReference type="EC" id="2.7.7.2" evidence="11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04615"/>
    <dbReference type="EnsemblBacteria" id="AQP44186">
        <property type="protein sequence ID" value="AQP44186"/>
        <property type="gene ID" value="RPIT_04615"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04615"/>
    <dbReference type="UniPathway" id="UPA00276">
        <property type="reaction ID" value="UER00406"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00277">
        <property type="reaction ID" value="UER00407"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003919">
        <property type="term" value="F:FMN adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008531">
        <property type="term" value="F:riboflavin kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006747">
        <property type="term" value="P:FAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009398">
        <property type="term" value="P:FMN biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02064">
        <property type="entry name" value="FAD_synthetase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015864">
        <property type="entry name" value="FAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002606">
        <property type="entry name" value="Riboflavin_kinase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="PTHR22749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06574">
        <property type="entry name" value="FAD_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004491">
        <property type="entry name" value="FAD_Synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="SSF82114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00083">
        <property type="entry name" value="ribF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 11" id="KW-0288">FMN</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Flavokinase" evidence="12">
        <location>
            <begin position="177"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR004491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP44186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="306" mass="33728" checksum="5245DB52494FDD31" modified="2017-04-12" version="1">MSVPDLPGTEESTMQTVVVIGNFDGVHRGHRRVLAEAVRDVDHPLVVITFWPHPVTVLRPESAPKLLSDLHTRIELLKEAGAHEVRVIRFNEAVAAMSPHDFIDRFLLPLNPVRVVVGENFRFGHAAAGDVQFLAEVGEGRFDVIPLPLESVRDEISCSTRIRELLAVGDVAGAAEHLERPFRFRGVVVLGDQRGRDLGYPTANQSVPVDMAVPADGVYAGWVTRLDEPGAMPMAAAISVGSNPTFDGSDRRVESYVIDRTDLELYGAEIAVDFVQRLRGQVRFSDVDELVLQMGRDVEQARRVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDN2</accession>
    <name>A0A1Q2CDN2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_04815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44219">
        <property type="protein sequence ID" value="AQP44219"/>
        <property type="gene ID" value="RPIT_04815"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04815"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025447">
        <property type="entry name" value="DUF4192"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13830">
        <property type="entry name" value="DUF4192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="292" mass="31379" checksum="96DD96A34A70C5FC" modified="2017-04-12" version="1">MKCTTRADLLAVPAVLFGFHPAESCVVMGMVGSTVGFTARLDLDWHLRGPRQISAQISNAAHEVGADEFVILGYAADPDLAFLSVTELTAALGPTRVRESLVTDGTRYWSLDDGEPFPFEFDTSSVAAQAVYEGRVISHDRAEAVSAVETWHPASPSEVDRVVEALGETADPEDRLWELLLAEDRLSDDDALELALLLSDTELADGVVGAFTIESAKAAWPNLLRARTVVPEEGQGEVLAVLAMASWLRGGGAEYTSLIEQLGRVAPDHPVTGTLEVMHQLGIPPSRWSECG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDT2</accession>
    <name>A0A1Q2CDT2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Deoxyguanosinetriphosphate triphosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05100"/>
    <dbReference type="EnsemblBacteria" id="AQP44268">
        <property type="protein sequence ID" value="AQP44268"/>
        <property type="gene ID" value="RPIT_05100"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05100"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026875">
        <property type="entry name" value="PHydrolase_assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13286">
        <property type="entry name" value="HD_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="2">
        <location>
            <begin position="111"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="368" mass="40204" checksum="926326C00DA26740" modified="2017-04-12" version="1">MDTPLPRTQQWAATMHGHGEGLVTAHATTTARTSPREPRRREEREALERASLVEGASLAVGAGDRLISEAPDPMRTCFERDRDRIVHSAAFRRLAGKTQVVVYPTDHQRTRLTHAIEVAQAAVAIARGVGANVTLVDAIALGHDCGHGPGGHASEDAFDEFIEGGYDHGPWGADVVLADLNLTRQTLDGIRNHSWSRPAPATLEGEIVSWADRIAYCAHDLEDAVYAGIVSLDDLPAVVRGVAGTTRRQQLATFINAVISTTARTGTVGMDQTTAEALGELRRFNYERIYTRPESVAQSVTVVRVLRDLVNYYLEAPSAMPAEYRHDDLVRGAVTYVGGMTDRFAFERAQHLLGWDPRKLPRGIGRCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDW1</accession>
    <name>A0A1Q2CDW1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Non-homologous end joining protein Ku</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ku</name>
        <name evidence="4" type="ORF">RPIT_05385</name>
        <name evidence="5" type="ORF">SAMN05428934_10324</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer. Interacts with LigD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prokaryotic Ku family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY65680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05385"/>
    <dbReference type="EnsemblBacteria" id="AQP44314">
        <property type="protein sequence ID" value="AQP44314"/>
        <property type="gene ID" value="RPIT_05385"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY65680">
        <property type="protein sequence ID" value="SDY65680"/>
        <property type="gene ID" value="SAMN05428934_10324"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05385"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00789">
        <property type="entry name" value="KU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01875">
        <property type="entry name" value="Prokaryotic_Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006164">
        <property type="entry name" value="Ku70/Ku80_beta-barrel_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009187">
        <property type="entry name" value="Prok_Ku"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016194">
        <property type="entry name" value="SPOC-like_C_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41251">
        <property type="entry name" value="PTHR41251"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02735">
        <property type="entry name" value="Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006493">
        <property type="entry name" value="Prok_Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00559">
        <property type="entry name" value="Ku78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100939">
        <property type="entry name" value="SSF100939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02772">
        <property type="entry name" value="Ku_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ku" evidence="3">
        <location>
            <begin position="53"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY65680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="269" mass="29633" checksum="D9496FAEA1093A14" modified="2017-04-12" version="1">MPRSIWKGSISFGLVSIPVKLYGATEDRDVSFRQVHSADGGRVRYQRVCEKCGEVLAYADIAKGYEAADGRIAILSDEDFENLPLRTLKSVDVVQFVDQDEVDPTYFQRTYFLEAEGPGQKPYVLLREALAKENKVAVVKVALRSRESLALVRAKDDLLLMHTMYWPDELRDGDFASPSSEVTVTDAEMEMAKLLIGQLEGEFDPAEYTDSYREALLEVVEAKLAGTALPEQSDTSAPTGDVVDLMAALKASVEAAKKRREDASAAKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE19</accession>
    <name>A0A1Q2CE19_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RCK N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44348">
        <property type="protein sequence ID" value="AQP44348"/>
        <property type="gene ID" value="RPIT_05580"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05580"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="1">
        <location>
            <begin position="2"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="119" mass="13308" checksum="DC5F644B67E9AAA3" modified="2017-04-12" version="1">MVWGVESNEMRARELTEAGYRVLEEDATDGEFWRRVRAAATVDLVLLAMPQHESNMLALEKLNASGFSGRVVAVVRHEEEEAELRRLEVDTLFNLYDGAGILLAKRGIEAIGLPHADDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE25</accession>
    <name>A0A1Q2CE25_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_05605</name>
        <name evidence="7" type="ORF">SAMN05428934_10368</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY66901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05605"/>
    <dbReference type="EnsemblBacteria" id="AQP44353">
        <property type="protein sequence ID" value="AQP44353"/>
        <property type="gene ID" value="RPIT_05605"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY66901">
        <property type="protein sequence ID" value="SDY66901"/>
        <property type="gene ID" value="SAMN05428934_10368"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05605"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030391">
        <property type="entry name" value="MeTrfase_TrmA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11061">
        <property type="entry name" value="PTHR11061"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05958">
        <property type="entry name" value="tRNA_U5-meth_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01231">
        <property type="entry name" value="TRMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRAM" evidence="5">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="332"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY66901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="379" mass="40675" checksum="64E783041570A640" modified="2017-04-12" version="1">MTIELSLERVAHGGYVVGRHEGKVIFVTGGLPGERVIAEVTERGRSFDRGHVVDVLEPSVGRVEPPCPIAGQCGGCDWQHADQATQLGLKTAVVAEQLQRLAGIEWDGSVEAVPGGLTDWRTRVRYAVTDDGRVGFRARRSHEVVPLPPQGCLIAADGPSVEELDGYANLGEDVRVTVADGSVTVLAGRMVVGPDPVFQRVGGRRYAVTADGFWQVHPEAAETLSRAVLDGLRPQRDERALDLYCGVGLFAGALVDAGCVVVGAEMGRAAVELARRNVREARFVTGPIERAQRDLPDWADLVVLDPPRKGAGASVVRAIAEREPRAIAYVACDPAALARDLATFAREGYSPVSIRAFDLFPMTHHVECVAILHPDHGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE82</accession>
    <name>A0A1Q2CE82_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44407">
        <property type="protein sequence ID" value="AQP44407"/>
        <property type="gene ID" value="RPIT_05915"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05915"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="94" mass="10250" checksum="9165859466AF18D4" modified="2017-04-12" version="1">MDPLQQLELAAREVERGDAAIFTAIVMVTMFYLGPWAWQCLAIGILSSCPSRTTVKMSPNVTAEEASDERRKMGCVRCIVDGVGFCAVGLYESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEB9</accession>
    <name>A0A1Q2CEB9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Bifunctional (P)ppGpp synthetase/guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">GTP pyrophosphokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_06290</name>
        <name evidence="8" type="ORF">SAMN05428934_103203</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate</text>
            <dbReference type="Rhea" id="RHEA:22088"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:142410"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; ppGpp biosynthesis; ppGpp from GTP: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the relA/spoT family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06290"/>
    <dbReference type="EnsemblBacteria" id="AQP44469">
        <property type="protein sequence ID" value="AQP44469"/>
        <property type="gene ID" value="RPIT_06290"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70329">
        <property type="protein sequence ID" value="SDY70329"/>
        <property type="gene ID" value="SAMN05428934_103203"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06290"/>
    <dbReference type="UniPathway" id="UPA00908">
        <property type="reaction ID" value="UER00884"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015970">
        <property type="term" value="P:guanosine tetraphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05399">
        <property type="entry name" value="NT_Rel-Spo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01668">
        <property type="entry name" value="TGS_RSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004811">
        <property type="entry name" value="RelA/Spo_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045600">
        <property type="entry name" value="RelA/SpoT_AH_RIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033655">
        <property type="entry name" value="TGS_RelA/SpoT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13291">
        <property type="entry name" value="ACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19296">
        <property type="entry name" value="DUF5913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00691">
        <property type="entry name" value="spoT_relA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HD" evidence="5">
        <location>
            <begin position="81"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="6">
        <location>
            <begin position="420"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="4">
        <location>
            <begin position="683"/>
            <end position="757"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY70329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="757" mass="84599" checksum="FE1918D50BD9DDCC" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEC2</accession>
    <name>A0A1Q2CEC2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Guanylate kinase</fullName>
            <ecNumber evidence="2 9">2.7.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">GMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gmk</name>
        <name evidence="11" type="ORF">RPIT_06160</name>
        <name evidence="12" type="ORF">SAMN05428934_103177</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential for recycling GMP and indirectly, cGMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + GMP = ADP + GDP</text>
            <dbReference type="Rhea" id="RHEA:20780"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the guanylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.8" evidence="2 9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY69626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06160"/>
    <dbReference type="EnsemblBacteria" id="AQP44447">
        <property type="protein sequence ID" value="AQP44447"/>
        <property type="gene ID" value="RPIT_06160"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY69626">
        <property type="protein sequence ID" value="SDY69626"/>
        <property type="gene ID" value="SAMN05428934_103177"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06160"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004385">
        <property type="term" value="F:guanylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00328">
        <property type="entry name" value="Guanylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017665">
        <property type="entry name" value="Guanylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020590">
        <property type="entry name" value="Guanylate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03263">
        <property type="entry name" value="guanyl_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00856">
        <property type="entry name" value="GUANYLATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="10">
        <location>
            <begin position="4"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="11"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY69626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="184" mass="20354" checksum="4CA9448932DD14A7" modified="2017-04-12" version="1">MASSDVWVISGPSGVGKGTVCARLRELHPEPFYSVSMTTRPPRPGEREAGSYHFVSPEDFRRLIETDQLLEWAVVHGTHYYGTPKQPVVDAVESGRPVVLEIDLQGARQVKQNLPSSKLVFLLPPTWDELVSRLKGRGTEDEEAQRRRLDTAKVELDAVAEADHAIENVEIEETVAALVGLMGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEF1</accession>
    <name>A0A1Q2CEF1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dihydroorotate dehydrogenase (quinone)</fullName>
            <ecNumber evidence="11">1.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">DHOdehase</fullName>
            <shortName evidence="11">DHOD</shortName>
            <shortName evidence="11">DHODase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Dihydroorotate oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">pyrD</name>
        <name evidence="13" type="ORF">RPIT_06175</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 11">Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>(S)-dihydroorotate + a quinone = a quinol + orotate</text>
            <dbReference type="Rhea" id="RHEA:30187"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="11">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 11">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; orotate from (S)-dihydroorotate (quinone route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 11">Cell membrane</location>
            <topology evidence="3 11">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 11">Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.2" evidence="11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06175"/>
    <dbReference type="EnsemblBacteria" id="AQP44450">
        <property type="protein sequence ID" value="AQP44450"/>
        <property type="gene ID" value="RPIT_06175"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06175"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00946"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004152">
        <property type="term" value="F:dihydroorotate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04738">
        <property type="entry name" value="DHOD_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00225">
        <property type="entry name" value="DHO_dh_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012135">
        <property type="entry name" value="Dihydroorotate_DH_1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005719">
        <property type="entry name" value="Dihydroorotate_DH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001295">
        <property type="entry name" value="Dihydroorotate_DH_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000164">
        <property type="entry name" value="DHO_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01036">
        <property type="entry name" value="pyrD_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00911">
        <property type="entry name" value="DHODEHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11" id="KW-0288">FMN</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 11" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHO_dh" evidence="12">
        <location>
            <begin position="55"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="11">
        <location>
            <begin position="119"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="11">
        <location>
            <begin position="258"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="70"/>
            <end position="74"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="330"/>
            <end position="331"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP44450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="351" mass="36291" checksum="E7D9321E3C1F8689" modified="2017-04-12" version="1">MGRPVITSGLRTGYHLVRSGLFRYGGGDPERAHEAMIGWLGRLPATTRATVRAPVDVAGIRFPNRVGLAAGMDKDGTAAAAWTRFGFGFAELGTVTALPQPGNPKPRIFRAVASQGIVNRMGFNNHGAGALAETLRAKGVARGNRALGIPLGISIGKSKVTPLEGAVDDYLTSLRALAPLADYVAVNVSSPNTPGLRALQSARELAQLLSALTSEAAALSPRPVPIFVKLAPDLVGDDFAETMAAINHSAVAGVIATNTTLARDGLAPSDRGLVDEPGGLSGRPLTRRALEFVEAVAGATDRPVMGVGGIMSPADGARMFGAGATLLQIYTGFIYEGPALVRGLNELEGNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEK4</accession>
    <name>A0A1Q2CEK4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06385</name>
        <name evidence="3" type="ORF">SAMN05428934_103222</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06385"/>
    <dbReference type="EnsemblBacteria" id="AQP44485">
        <property type="protein sequence ID" value="AQP44485"/>
        <property type="gene ID" value="RPIT_06385"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70849">
        <property type="protein sequence ID" value="SDY70849"/>
        <property type="gene ID" value="SAMN05428934_103222"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06385"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY70849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="189" mass="19976" checksum="ACC79015B5B8F72C" modified="2017-04-12" version="1">MADDLLVVSRGGQLADLWERPAWRVTAYLVLVAALGAIGGLLWSALTPLSSYTVREELNAAITERGQAQIVAGDVVFALLAALIGLVVGVVGWAILHRRGWLVTFVPVLAAAAAALVMWRVGTMVGQTGFSVRLAAAAPGDTVPIDLQLRSMAALLVAPFAAVTPIMLLAAFWPEPRREQPRPPSVVAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEQ0</accession>
    <name>A0A1Q2CEQ0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA dimethylallyltransferase</fullName>
            <ecNumber evidence="5">2.5.1.75</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Dimethylallyl diphosphate:tRNA dimethylallyltransferase</fullName>
            <shortName evidence="5">DMAPP:tRNA dimethylallyltransferase</shortName>
            <shortName evidence="5">DMATase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Isopentenyl-diphosphate:tRNA isopentenyltransferase</fullName>
            <shortName evidence="5">IPP transferase</shortName>
            <shortName evidence="5">IPPT</shortName>
            <shortName evidence="5">IPTase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">miaA</name>
        <name evidence="9" type="ORF">RPIT_07055</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5 7">Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5 6">
            <text>adenosine(37) in tRNA + dimethylallyl diphosphate = diphosphate + N(6)-dimethylallyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:26482"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="EC" id="2.5.1.75"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 8">Belongs to the IPP transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.75" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07055"/>
    <dbReference type="EnsemblBacteria" id="AQP44602">
        <property type="protein sequence ID" value="AQP44602"/>
        <property type="gene ID" value="RPIT_07055"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07055"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052381">
        <property type="term" value="F:tRNA dimethylallyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00185">
        <property type="entry name" value="IPP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039657">
        <property type="entry name" value="Dimethylallyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018022">
        <property type="entry name" value="IPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088">
        <property type="entry name" value="PTHR11088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00174">
        <property type="entry name" value="miaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <begin position="40"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="10"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="332" mass="36298" checksum="B6FD50ECE0C31491" modified="2017-04-12" version="1">MPVPLVVLVGPTATGKSRLAVDVALALAESGQPAEIINADSMLVYRGMDIGTAKPTEAERRGVPHHLIDIAEVTERTSVAEFQTLARGVIARLRDAGTVPIVVGGSALYTRAITDHFDFPGSDDEVRARWEAELARVGPHELHRRLAEIAPESAAKIEPGNGRRTVRALEVAELTGGHRPSLPEWTYELSDVHQFGLWLDRAELDARIDGRVEQMWADGLVEEVRALLDRGLREGETAVRAIGYRQVVQFLDGELSEREAKAAVQRATRTFFRKQLGWYRRDPRITWLDATSASNVAAVLAGIGLGTTAEGEVGASIQLPQGARDPERLHHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEX4</accession>
    <name>A0A1Q2CEX4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_07410</name>
        <name evidence="4" type="ORF">SAMN05428934_11439</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000014">
        <property type="protein sequence ID" value="SDZ18560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07410"/>
    <dbReference type="EnsemblBacteria" id="AQP44658">
        <property type="protein sequence ID" value="AQP44658"/>
        <property type="gene ID" value="RPIT_07410"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ18560">
        <property type="protein sequence ID" value="SDZ18560"/>
        <property type="gene ID" value="SAMN05428934_11439"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07410"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041682">
        <property type="entry name" value="AAA_14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025420">
        <property type="entry name" value="DUF4143"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13173">
        <property type="entry name" value="AAA_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13635">
        <property type="entry name" value="DUF4143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_14" evidence="1">
        <location>
            <begin position="23"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4143" evidence="2">
        <location>
            <begin position="205"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ18560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="428" mass="46087" checksum="EFA9453500461CDE" modified="2017-04-12" version="1">MVLDTLVPRRVGELLTGLVAVEPVIALHGPRSVGKSTVLRRFAADAGGSVLDLDDVEVREAVEGNLASVVAGAAPVCVDEYQRVPDILDALKARLNREGSLPGTAVITGSTRQDALPATAQALTGRLHSLTIWPLSQGEIAEVSENLIEVLPADPEGVVGRIPSSTTTRQDYVERVCAGGLPLALRRSGAARARWFDDFVRASVERDALELSRIRERQAMTDLLGLIAAQTGQLLNVSAAAERLGVSRATVEGHLRLLEDLFLVVRLPAWGKTLRSRVSVKPKVHVVDSGLAARLLRLTPDKLTRLDPASLTDFGHLLETFVVGEIRKQASWLDEPVALGHWRTSDGAEVDLVIEYDDGTVIAFEVKASERAPGGDFRGLGQLRDALGSRFAGGIILTTGTRSYTYADRLHVMPIDRLWTPVTPGAPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEY0</accession>
    <name>A0A1Q2CEY0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_07435</name>
        <name evidence="9" type="ORF">SAMN05428934_11444</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000014">
        <property type="protein sequence ID" value="SDZ18664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07435"/>
    <dbReference type="EnsemblBacteria" id="AQP44661">
        <property type="protein sequence ID" value="AQP44661"/>
        <property type="gene ID" value="RPIT_07435"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ18664">
        <property type="protein sequence ID" value="SDZ18664"/>
        <property type="gene ID" value="SAMN05428934_11444"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07435"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="7">
        <location>
            <begin position="261"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="731"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="282"/>
            <end position="289"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ18664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="751" mass="81066" checksum="E0010674AF99B76D" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF13</accession>
    <name>A0A1Q2CF13_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GAF domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07625</name>
        <name evidence="3" type="ORF">SAMN05428934_1216</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000021">
        <property type="protein sequence ID" value="SDZ22683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07625"/>
    <dbReference type="EnsemblBacteria" id="AQP44691">
        <property type="protein sequence ID" value="AQP44691"/>
        <property type="gene ID" value="RPIT_07625"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ22683">
        <property type="protein sequence ID" value="SDZ22683"/>
        <property type="gene ID" value="SAMN05428934_1216"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07625"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF13185">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAF" evidence="1">
        <location>
            <begin position="27"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ22683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="238" mass="25549" checksum="41C8777BC4057123" modified="2017-04-12" version="1">MRQPEQRDLASLDTLSRVANDLAGEFRLEPLLELILRSSVTLLGCESGSLCLVEPHTHTYRKQIDVQAGCQAGRVFPLEEGVTGAVARAGRPVTFRHYADVPGGHVSADSPLYNRAVIGVPIRLRSDLLGSLVVFAPDDEYCFGDADAQLLQRFATHAAIAMANARLHAEAADRAKAAAVWAERERSMLDVQDALGRGLATVLLELAHAEELALAEQPVGAVVALAAGLPLFLRRDLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF27</accession>
    <name>A0A1Q2CF27_9ACTN</name>
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            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44708">
        <property type="protein sequence ID" value="AQP44708"/>
        <property type="gene ID" value="RPIT_07720"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07720"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="73" mass="7621" checksum="D2D9F34F93AA99C7" modified="2017-04-12" version="1">MLDLIAALSEAGVAAPDGEVGYELDGVPFELVWTSEKIAVQLDPAPDVEVDGWRILAPDAASIAAAWKQQTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF62</accession>
    <name>A0A1Q2CF62_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-hydroxyhepta-2,4-diene-1,7-dioate isomerase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (Catechol pathway)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_07935</name>
        <name evidence="4" type="ORF">SAMN05428934_11327</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07935"/>
    <dbReference type="EnsemblBacteria" id="AQP44743">
        <property type="protein sequence ID" value="AQP44743"/>
        <property type="gene ID" value="RPIT_07935"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16504">
        <property type="protein sequence ID" value="SDZ16504"/>
        <property type="gene ID" value="SAMN05428934_11327"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016853">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
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        <location>
            <begin position="67"/>
            <end position="264"/>
        </location>
    </feature>
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    </evidence>
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            <dbReference type="Pfam" id="PF10370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ16504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="267" mass="28463" checksum="688A8CB0393038D4" modified="2017-04-12" version="1">MRIARFAKAGQDPTYGIIELAVDGGEHPDTIAALTSDPLAGVAVNYTGERHDLDDVRLLAPVIPRSKVVGVGRNYAAHAAELGNEVPAEPLLFFKPNTSVIGPTDTILLPDGADEVHFEGELAIVIGRICKEVPVERAADVIFGYTIANDVTCRNWQQSDGQWARAKGADTFCPIGPWINTHLTPDEAGRLSLQSHVNGELKQDSNTSHMIRGVAELVSYISAFTTLLPGDLILTGTPEGVGLIRPGDEVNIDIDGLGTLSNPVDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFE4</accession>
    <name>A0A1Q2CFE4_9ACTN</name>
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    </gene>
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
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            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44828">
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        <property type="gene ID" value="RPIT_08500"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY96369"/>
        <property type="gene ID" value="SAMN05428934_10711"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
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            <begin position="29"/>
            <end position="206"/>
        </location>
    </feature>
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        <location>
            <begin position="151"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
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            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
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            <dbReference type="EMBL" id="AQP44828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
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            <dbReference type="EMBL" id="SDY96369.1"/>
        </source>
    </evidence>
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            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="206" mass="20659" checksum="DBA4FF561AAC479B" modified="2017-04-12" version="1">MSRSPLGFAALPAAAALLLGGVALTANAAPTTAAECVRDGLVWVHVQYDDTVTGACANEFDTASEALLSTGLTTDTGAWLSTVDGRAADSGAREYWGVWTQSPADGVYSGAWEFAQVGILELTLEAGDVLGVDLEADWDLESAAPTVDPVAGLDLTAPETTPTTPAPSPTPTASASPEGPGSGADCDDPSALPINPECIGAPSTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFF8</accession>
    <name>A0A1Q2CFF8_9ACTN</name>
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        <name evidence="5" type="ORF">SAMN05428934_10754</name>
    </gene>
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44862">
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        <property type="gene ID" value="RPIT_08720"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY97377"/>
        <property type="gene ID" value="SAMN05428934_10754"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08720"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <begin position="171"/>
            <end position="236"/>
        </location>
    </feature>
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            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY97377.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="255" mass="27900" checksum="58537FB1C06264F4" modified="2017-04-12" version="1">MKLSEWSMVAAEVLNEPSPRQARVLLAHALLRGFGAQQVARVRVDDDGTANWYLAGDDVPPPEALPTGADVERHPLHRFHVGAGVRTPSLLTDALAQGWRFEPDTWALIERLHLTLHQFSLPIEWGRHYDGWVLVSDEGFHARAVSMGEHLQALIVGLDRHIRLLAAAGTEDGSAVGLTARETVVLHLMARGLTATSIGARLRISPRTVHKHQERLYRKLGAVDRLSAVLRAQEAGALPPQHPGPLSVEGYSSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFH5</accession>
    <name>A0A1Q2CFH5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Radical SAM protein</fullName>
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    </protein>
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        <name evidence="2" type="ORF">RPIT_08735</name>
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        <lineage>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="16"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="232" mass="25052" checksum="AD026A5F70FF11CA" modified="2017-04-12" version="1">MGNRQPPVQQAPPAQKLRLRYAKRGPGRFTSHRDFGRALERALRRAEIPMAYSSGFSPHPRISYANASPTSAASEAEYVELGLAEVCDPAKVMGALNEVLPQGFVVLDVAEARKESLGDLLEASDWIISLPGAPAGVLASAVSALLAADDYTVERMTKSGMRSFDVRSAILSLDCADDETLRLRARHQTPLVRPDDVVTALRGIDDRVPSLPLLTRLAQGPLTDGEIGDPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFK8</accession>
    <name>A0A1Q2CFK8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent Clp protease ATP-binding subunit ClpX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">clpX</name>
        <name evidence="10" type="ORF">RPIT_08800</name>
        <name evidence="11" type="ORF">SAMN05428934_10770</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the ClpX chaperone family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08800"/>
    <dbReference type="EnsemblBacteria" id="AQP44877">
        <property type="protein sequence ID" value="AQP44877"/>
        <property type="gene ID" value="RPIT_08800"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97731">
        <property type="protein sequence ID" value="SDY97731"/>
        <property type="gene ID" value="SAMN05428934_10770"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08800"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00175">
        <property type="entry name" value="ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004487">
        <property type="entry name" value="Clp_protease_ATP-bd_su_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046425">
        <property type="entry name" value="ClpX_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001496">
        <property type="entry name" value="SOCS_box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010603">
        <property type="entry name" value="Znf_CppX_C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038366">
        <property type="entry name" value="Znf_CppX_C4_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06689">
        <property type="entry name" value="zf-C4_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00994">
        <property type="entry name" value="zf-C4_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00382">
        <property type="entry name" value="clpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51902">
        <property type="entry name" value="CLPX_ZB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50225">
        <property type="entry name" value="SOCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ClpX-type ZB" evidence="9">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="SOCS box" evidence="8">
        <location>
            <begin position="41"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="124"/>
            <end position="131"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY97731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="425" mass="46338" checksum="1EA077AD50A38ADE" modified="2017-04-12" version="1">MARIGESGDLFKCNFCGKSQKQVKKLIAGPGVYICDECIALCNEIIEEEFPETTDTGLVEELPKPREIRDFLDSYVIGQDTAKKTLSVAVYNHYKRIQAQQSHGRRAENDDVEVGKSNILLIGPTGCGKTYLAQTLAKMLNVPFAMADATALTEAGYVGEDVENILLKLIQAADFDIAKAETGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQDFLQIDTTKILFIVGGAFAGLEEIINARVGKRPLGFNNSAEAREPSAEPFAQVRPEDLHKFGLIPEFIGRLPMLTSVSPLDRDALVRILVEPKNALTRQFQKLFELDGVQLEFTDDAVGAIADLALERGTGARGLRAILESLLLETMFDVPSDEDVAQVVVTAEAVRGEALPTLIPRAQLASRRDLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFU3</accession>
    <name>A0A1Q2CFU3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">IclR helix-turn-helix domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">MarR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09360</name>
        <name evidence="3" type="ORF">SAMN05428934_102437</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY60761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44967">
        <property type="protein sequence ID" value="AQP44967"/>
        <property type="gene ID" value="RPIT_09360"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY60761">
        <property type="protein sequence ID" value="SDY60761"/>
        <property type="gene ID" value="SAMN05428934_102437"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09360"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="23"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY60761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="111" mass="12074" checksum="44FBB202A968EF34" modified="2017-04-12" version="1">MLEKEALRGLSRAAFGQAYRLEVMLAVADSADGLTTQTELARELGVSVSNVQGPVRSLIGCGLLTELPQGDSRSKFLMRNRSAAWEWAQELALHSRATFRADAGNRLALEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFY5</accession>
    <name>A0A1Q2CFY5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_09285</name>
        <name evidence="2" type="ORF">RPIT_13440</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09285"/>
    <dbReference type="EnsemblBacteria" id="AQP44955">
        <property type="protein sequence ID" value="AQP44955"/>
        <property type="gene ID" value="RPIT_09285"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45690">
        <property type="protein sequence ID" value="AQP45690"/>
        <property type="gene ID" value="RPIT_13440"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09285"/>
    <dbReference type="KEGG" id="tfl:RPIT_13440"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="240" mass="26434" checksum="4956D478628B288B" modified="2017-04-12" version="1">MSEHGCCRQQNGVMTMTLLEGEPAAGPWRALDTAELVNHVLQVAGQPLGRPQIVAVDGRGASGKSTLAAELKRAVARSAVVHTDDLAWHEPFFAWGHLLRDEILVTLHRGEGVRFQPPAWGLHGREGVIEVAAEADLVVIEGVGASQREFEHFVDASIWVQSDFQEAERRGIARDMAEGVNGDREQTIAFWHEWMAHEVRFLAEQRPWERACLVVAGSPTIDLDEGQFAVAPAPSNNPWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG08</accession>
    <name>A0A1Q2CG08_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonuclease PH</fullName>
            <shortName evidence="4">RNase PH</shortName>
            <ecNumber evidence="4">2.7.7.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA nucleotidyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rph</name>
        <name evidence="7" type="ORF">RPIT_09500</name>
        <name evidence="8" type="ORF">SAMN05428934_102406</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>phosphate + tRNA(n+1) = a ribonucleoside 5'-diphosphate + tRNA(n)</text>
            <dbReference type="Rhea" id="RHEA:10628"/>
            <dbReference type="Rhea" id="RHEA-COMP:17343"/>
            <dbReference type="Rhea" id="RHEA-COMP:17344"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:173114"/>
            <dbReference type="EC" id="2.7.7.56"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homohexameric ring arranged as a trimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.56" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY59908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09500"/>
    <dbReference type="EnsemblBacteria" id="AQP44990">
        <property type="protein sequence ID" value="AQP44990"/>
        <property type="gene ID" value="RPIT_09500"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59908">
        <property type="protein sequence ID" value="SDY59908"/>
        <property type="gene ID" value="SAMN05428934_102406"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09500"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009022">
        <property type="term" value="F:tRNA nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11362">
        <property type="entry name" value="RNase_PH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00564">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002381">
        <property type="entry name" value="RNase_PH_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018336">
        <property type="entry name" value="RNase_PH_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01966">
        <property type="entry name" value="RNasePH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01277">
        <property type="entry name" value="RIBONUCLEASE_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 4" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="RNase_PH" evidence="5">
        <location>
            <begin position="14"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="RNase_PH_C" evidence="6">
        <location>
            <begin position="162"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate (substrate) binding" evidence="4">
        <location>
            <begin position="128"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <note>substrate</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY59908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="241" mass="25679" checksum="58C3DFB846F227BA" modified="2017-04-12" version="1">MGPTTRNDGRSPDQLREVRITRNWLDHAEGSVLVEFGKTRVLVAASVTVGVPRWRTGSGLGWVTAEYSMLPRATHTRSDREAVKGRIGGRTHEISRLIGRSLRAVVDYRALGENTIVLDCDVLQADGGTRTAAITGAYVALEDAVSHLRALGALKGEPLKDSVAAVSVGFHNGVPLLDLNYEEDAAAGTDMNIVMTGSGQFIEVQGTAEGTPFSRDELGALLDLGTAGCAELTRLQRAALQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG85</accession>
    <name>A0A1Q2CG85_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vancomycin resistance protein YoaR, contains peptidoglycan-binding and VanW domains</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_10265</name>
        <name evidence="4" type="ORF">SAMN05428934_102252</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10265"/>
    <dbReference type="EnsemblBacteria" id="AQP45128">
        <property type="protein sequence ID" value="AQP45128"/>
        <property type="gene ID" value="RPIT_10265"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55639">
        <property type="protein sequence ID" value="SDY55639"/>
        <property type="gene ID" value="SAMN05428934_102252"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10265"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022029">
        <property type="entry name" value="PG-bd_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007391">
        <property type="entry name" value="Vancomycin_resist_VanW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12229">
        <property type="entry name" value="PG_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04294">
        <property type="entry name" value="VanW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_4" evidence="2">
        <location>
            <begin position="91"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY55639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="566" mass="60515" checksum="B1AA01F9A3CF7D47" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG89</accession>
    <name>A0A1Q2CG89_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Biotin-requiring enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_10245</name>
        <name evidence="5" type="ORF">SAMN05428934_102256</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10245"/>
    <dbReference type="EnsemblBacteria" id="AQP45124">
        <property type="protein sequence ID" value="AQP45124"/>
        <property type="gene ID" value="RPIT_10245"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55750">
        <property type="protein sequence ID" value="SDY55750"/>
        <property type="gene ID" value="SAMN05428934_102256"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10245"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0092">Biotin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="3">
        <location>
            <begin position="92"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="68"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY55750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="167" mass="18268" checksum="201FBD0EED55E74D" modified="2017-04-12" version="1">MRRYTIGINDTTKIVDVEAVGANEFRVQIDGRLIDVTLEDHRDLAHSAITPAMVPRAEITHGSLAGEEPVAQPVQQRPRQPADATNAPVANPTQPVDRDQMTAPMPGVILSIDVTTGAEVKRGDTLMVLEAMKMKNQLRSPRDGVVAELYVSVGTQVRFGETLLRFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGE5</accession>
    <name>A0A1Q2CGE5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Uracil-DNA glycosylase</fullName>
            <shortName evidence="8">UDG</shortName>
            <ecNumber evidence="4 8">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ung</name>
        <name evidence="11" type="ORF">RPIT_10585</name>
        <name evidence="12" type="ORF">SAMN05428934_102188</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="4 8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY53738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10585"/>
    <dbReference type="EnsemblBacteria" id="AQP45188">
        <property type="protein sequence ID" value="AQP45188"/>
        <property type="gene ID" value="RPIT_10585"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY53738">
        <property type="protein sequence ID" value="SDY53738"/>
        <property type="gene ID" value="SAMN05428934_102188"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10585"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10027">
        <property type="entry name" value="UDG-F1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00148">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002043">
        <property type="entry name" value="UDG_fam1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018085">
        <property type="entry name" value="Ura-DNA_Glyclase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264">
        <property type="entry name" value="PTHR11264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00130">
        <property type="entry name" value="U_DNA_GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="10">
        <location>
            <begin position="52"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP45188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY53738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="225" mass="24168" checksum="32E4EA88E91AD8FE" modified="2017-04-12" version="1">MPKPLADLVSPDWADALAPVEGQIAAMGSFLRDEIADGHSYLPAGDQILRAFTRPLADVRVLILGQDPYPTVGHPVGLSFSVARDVRPLPGSLRNIYRELASDLGVEAPDHGDLTSWFEQGVLLLNRVLTVRPGAPASHRGKGWEEVTARAVEALARRGGPLVAILWGRDAQSATPMLGDVPIIASAHPSPLSARSGFYGSRPFSRANRHLEEQGAAPIDWQIPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGF7</accession>
    <name>A0A1Q2CGF7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MBL fold metallo-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_10640</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10640"/>
    <dbReference type="EnsemblBacteria" id="AQP45196">
        <property type="protein sequence ID" value="AQP45196"/>
        <property type="gene ID" value="RPIT_10640"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10640"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="1"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-Casp" evidence="3">
        <location>
            <begin position="229"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="460" mass="50967" checksum="B63299265E7893D9" modified="2017-04-12" version="1">MTIGDRRILVDAGMFQGEKMWRLKNREDFPVDPSTISDVLLTHAHTDHAAYLPALVKHGFRGAIYATEATIRLAEIVLRDSGRLQEQAVGDAVRGGYSKHEQPEALYTTDDVEATLPLFRSVEWNSDVEIDGVTARWVRSAHILGSASIHVTVGERSVLFSGDLGRHDHPILKDRETPPGADIVLCESTYGDREHPEPELPHEPFADAIRRTVAAGGQVVVPAFAIDRTETVLHALVQMRRAGRIPDVPVVVDGPMSLRALDVYKDESLGELDHDITIADFTDLNLSEARDGRDSKKLNRRTDPMIIISSSGMAEGGRVLYHLMRLLPDPKNTVVLTGYQAEGTRGRALEDGARNVKINGRHIRVKANIVRDHEFSVHGDASDLMDWLKALDKEPETVYVTHGEHHVAETFADRIENELDWAAVVPKYGEVVSIMGDGWDPEDLDVEVPEPQAAGTEPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGM2</accession>
    <name>A0A1Q2CGM2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized conserved protein, DUF2249 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11075</name>
        <name evidence="3" type="ORF">SAMN05428934_10289</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY50670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11075"/>
    <dbReference type="EnsemblBacteria" id="AQP45269">
        <property type="protein sequence ID" value="AQP45269"/>
        <property type="gene ID" value="RPIT_11075"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY50670">
        <property type="protein sequence ID" value="SDY50670"/>
        <property type="gene ID" value="SAMN05428934_10289"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11075"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018720">
        <property type="entry name" value="DUF2249"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10006">
        <property type="entry name" value="DUF2249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2249" evidence="1">
        <location>
            <begin position="23"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY50670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="93" mass="9967" checksum="C6120A4FF5486B7E" modified="2017-04-12" version="1">MTELNLTAKSGCGCGGHDESLPELDARVIPHAVRHAAIHGVVDSLQTGSAFVLVAPHDPVPLLRQINDRHGDNIAVSYVQEGPEAWKLKLARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGN9</accession>
    <name>A0A1Q2CGN9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Copper-containing nitrite reductase</fullName>
            <ecNumber evidence="5">1.7.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_11060</name>
        <name evidence="12" type="ORF">SAMN05428934_10292</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Fe(III)-[cytochrome c] + H2O + nitric oxide = Fe(II)-[cytochrome c] + 2 H(+) + nitrite</text>
            <dbReference type="Rhea" id="RHEA:15233"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16301"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.7.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(+)</name>
            <dbReference type="ChEBI" id="CHEBI:49552"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.7.2.1" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY50771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11060"/>
    <dbReference type="EnsemblBacteria" id="AQP45267">
        <property type="protein sequence ID" value="AQP45267"/>
        <property type="gene ID" value="RPIT_11060"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY50771">
        <property type="protein sequence ID" value="SDY50771"/>
        <property type="gene ID" value="SAMN05428934_10292"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11060"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050421">
        <property type="term" value="F:nitrite reductase (NO-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001287">
        <property type="entry name" value="NO2-reductase_Cu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="PTHR11709"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00695">
        <property type="entry name" value="CUNO2RDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="297"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="342"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="365"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="417"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="10">
        <location>
            <begin position="599"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="547"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP45267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY50771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="864" mass="91397" checksum="66FCD2BF042651E8" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGQ0</accession>
    <name>A0A1Q2CGQ0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cystathionine gamma-synthase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">O-succinylhomoserine (Thiol)-lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_11240</name>
        <name evidence="5" type="ORF">SAMN05428934_10255</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY49738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11240"/>
    <dbReference type="EnsemblBacteria" id="AQP45298">
        <property type="protein sequence ID" value="AQP45298"/>
        <property type="gene ID" value="RPIT_11240"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY49738">
        <property type="protein sequence ID" value="SDY49738"/>
        <property type="gene ID" value="SAMN05428934_10255"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11240"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011821">
        <property type="entry name" value="O_succ_thio_ly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="PTHR11808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02080">
        <property type="entry name" value="O_succ_thio_ly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY49738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="385" mass="40804" checksum="7E6EFE69208FBCEB" modified="2017-04-12" version="1">MAELGRWTRGMRTGLGADPAYGAVVPPLYLTTNFTFEAYDRPREYDYSRSGNPTRDLLADAIATLEGGAGGTVVATGLAAITLVVEALVPVGGRVVVPHDCYGGSWRLFAFLADRGRLTVDFVDFNDEPALAAALDRSPALVWIETPSNPLLRITDLASTTEAAHRAGALVAADNTFLSPLLQRPLEHGVDIVIHSTTKFLNGHSDVVGGVAVAATAEHHELLRQWANVLGLTGSPFDAYQTLRGLRTLDARMRVHQENAATLVEACNGHPAVAAVHYPGLTDHPGHDVAARQQDGFGSLFSIDLTGGVDAVTRFLEGLPIFHLAESLGGIESLVCHPARMTHAGMTDEARAAAGIGDGLLRFSIGLESPDDLVAVVAEALDRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGS4</accession>
    <name>A0A1Q2CGS4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine hydroxymethyltransferase</fullName>
            <shortName evidence="7">SHMT</shortName>
            <shortName evidence="7">Serine methylase</shortName>
            <ecNumber evidence="7">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glyA</name>
        <name evidence="10" type="ORF">RPIT_11275</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; glycine biosynthesis; glycine from L-serine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the SHMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11275"/>
    <dbReference type="EnsemblBacteria" id="AQP45303">
        <property type="protein sequence ID" value="AQP45303"/>
        <property type="gene ID" value="RPIT_11275"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11275"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="UniPathway" id="UPA00288">
        <property type="reaction ID" value="UER01023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="PTHR11680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4 7" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SHMT" evidence="9">
        <location>
            <begin position="30"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="SHMT" evidence="9">
        <location>
            <begin position="166"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="177"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="415"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7 8">
        <location>
            <position position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP45303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="489" mass="52479" checksum="390C2B87C915DA21" modified="2017-04-12" version="1">MGPHTPLLRRIVSDLESISSAYRTLLSAIEEVEPRIAAATRQELTDQRASLKLIASENYASLPVLATMGTWLSDKYAEGTVGHRFYAGCQNVDTVEAVAAEHARELFGAEYAYVQPHSGIDANLTAYWAILAHKVESPALAEFGAKGVADLTEADWETLRRRFGEQRLLGMSLDAGGHLTHGFRPNVSGKMFHQRSYGTDPETQLLDYDVIRAQAREFRPLILVAGYSAYPRRVNFAKMRDIADEVGAVLMVDMAHFAGLVAGKVFTGEEDPVPYADVVTTTTHKSLRGPRGGMVLATGEYAPSVDRGCPLVLGGPLSNVMAAKAVALAEARTAEFQTYAQAVADNAQALAEGLLRRGVDLVTGGTDNHLVLMDVRSFGLTGRQAESALLESGIVTNRNAVPNDPNGAWYTTGVRLGTPALTSRGFTASDMDAVADMIAGVLGSTTPTTTSKGEPSKAKYDLTDDARDGSLAEAQRLLNLHPLYPGLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGU5</accession>
    <name>A0A1Q2CGU5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cephalosporin-C deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11380</name>
        <name evidence="3" type="ORF">SAMN05428934_10228</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY48838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11380"/>
    <dbReference type="EnsemblBacteria" id="AQP45323">
        <property type="protein sequence ID" value="AQP45323"/>
        <property type="gene ID" value="RPIT_11380"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY48838">
        <property type="protein sequence ID" value="SDY48838"/>
        <property type="gene ID" value="SAMN05428934_10228"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11380"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008391">
        <property type="entry name" value="AXE1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039069">
        <property type="entry name" value="CE7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40111">
        <property type="entry name" value="PTHR40111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05448">
        <property type="entry name" value="AXE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AXE1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY48838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="330" mass="36057" checksum="6BCAA9BB4D089CEE" modified="2017-04-12" version="1">MAFFDLSPAELASYAPDLDEPADFDEFWTRTFDEHGAGPLDFTCEPVETHLTVLDAFEISWRGFDGHRVYGWLALPNGVDGPLPAVVQYTGYSMGRGMPFENIQFAVGGYAQFVIDARGQGWRNGSTKLGSEDPGLRTSGSVPGFMTAGVLNAEGYYYRRLFVDAVRLAEAAAGHDRVDAGRLFVTGGSQGGAMALAVAGLAQLRGVQIAGCAPEVPFMCHFTRAIGLTDAYPYKEVADYLASYPQRQRQVMRTLSYFDGMSMAARATMPGLFSVGLMDQITPPSTVYAAYHHYAGEKAIEVYPFNGHEGGTTYQLKQIHHWLAELLGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGW6</accession>
    <name>A0A1Q2CGW6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Orotate phosphoribosyltransferase</fullName>
            <shortName evidence="4">OPRT</shortName>
            <shortName evidence="4">OPRTase</shortName>
            <ecNumber evidence="2 4">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pyrE</name>
        <name evidence="6" type="ORF">RPIT_11595</name>
        <name evidence="7" type="ORF">SAMN05428934_106156</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate</text>
            <dbReference type="Rhea" id="RHEA:10380"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="2 4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY94091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11595"/>
    <dbReference type="EnsemblBacteria" id="AQP45361">
        <property type="protein sequence ID" value="AQP45361"/>
        <property type="gene ID" value="RPIT_11595"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY94091">
        <property type="protein sequence ID" value="SDY94091"/>
        <property type="gene ID" value="SAMN05428934_106156"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11595"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 4" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="5">
        <location>
            <begin position="60"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-phosphoribose 1-diphosphate binding" evidence="4">
        <location>
            <begin position="121"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY94091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="179" mass="18691" checksum="6C0D6DFA6355D8AA" modified="2017-04-12" version="1">MTDRTELIEHIKHLAVVHGRVTLASGKEADYYVDMRRVTLDGAASPLVGRVMNDLVSDLEFDAVGGLTLGADPVATAMLHARAAAGGRLDAFVVRKQSKAHGLQRQIEGTEVSGRRVLVVEDTSTTGGSALTAVEAVREAGGEVVAVAVVVDRGTGAAERIAEAGLEYRYAVGLADLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGX7</accession>
    <name>A0A1Q2CGX7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Hemolysin, contains CBS domains</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_11575</name>
        <name evidence="13" type="ORF">SAMN05428934_106160</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY94195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11575"/>
    <dbReference type="EnsemblBacteria" id="AQP45357">
        <property type="protein sequence ID" value="AQP45357"/>
        <property type="gene ID" value="RPIT_11575"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY94195"/>
        <property type="gene ID" value="SAMN05428934_106160"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11575"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
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        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
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        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
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        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="94"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="11">
        <location>
            <begin position="3"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="224"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="285"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP45357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY94195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="451" mass="48240" checksum="C510FA1FC6D91C3E" modified="2017-04-12" version="1">MTPVVSLLVGIVVVLGITAATGYFVAQEFAYMAVDRSQLGSRAKAGDKKASNTLEITRRTSFMLSGAQLGITVTGLLVGYVAEPLIGQAIGSLISGGALTAVSVAIGGFIAIALSTIIQMLFGELFPKNYAIARSARVADALTPSTRLYLKLFGPLIWVFDRSAELLLRALKIEPVHDVESAASADDLERVVAASRDSGTLSPELAAIVDRVIDFPRRDAEHAMVPRVQVDVVHDDTPIGEVRTLMATGHTRYPVLDERGDAIGLVQMVDVLDRPVNDPAPVSAIMRDAVRVSEFTDLPTTEQLLRQSGQELACVVDEFGSFVGIVTLEDLAEEIVGELTDEHDPDDPGYLPQEGDGIWVMPGDVHVDEVERAIGLKLPQGDYETIAGLVIHAVGDLPDVGAVIDLTLEPNVAQLALDDDAPSRHVEIEVLAVERHVPSRVRVSLPEGDNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH06</accession>
    <name>A0A1Q2CH06_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_11815</name>
        <name evidence="4" type="ORF">SAMN05428934_106112</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11815"/>
    <dbReference type="EnsemblBacteria" id="AQP45401">
        <property type="protein sequence ID" value="AQP45401"/>
        <property type="gene ID" value="RPIT_11815"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93128">
        <property type="protein sequence ID" value="SDY93128"/>
        <property type="gene ID" value="SAMN05428934_106112"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11815"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018723">
        <property type="entry name" value="DUF2254_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10011">
        <property type="entry name" value="DUF2254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY93128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="417" mass="45489" checksum="547B70B616BE9966" modified="2017-04-12" version="1">MATSRSRGSVNAIEQATLWDRMWQPFWVLPVAMTLGALAMALVLPELDKELRGWMFWVFPGGADAARGALTTIASATISTVGVVFSITMVVLQLASSSFTPRILGSFLESRVVQATFGMFIATFVFSLIALRAILNETDDSSGFVPRVSVTFAFLMAIGCVGLFLAFVRHITESIQVSKVISRIGDRTLRLIERVLPGQDENGGAGPTWSPTAGTPSTRIQVGERHGHLDEIDLPELVRLAGELEGVIVLERSLGAFVTHGQPLATFWGEGWDEDAQSRLASAMRLATERTTRQDVSFGFRQLVDIGDRALSPGTNDPTTANQVINELHRLLRVIVQRVVPSPYIADDDGVVRVVAQGSDVETLLTLSVQELAHFARDIPPVLRRLQLMLDDLDSCALPRYQGSIDALRETVASYAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH25</accession>
    <name>A0A1Q2CH25_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11965</name>
        <name evidence="3" type="ORF">SAMN05428934_10682</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11965"/>
    <dbReference type="EnsemblBacteria" id="AQP45426">
        <property type="protein sequence ID" value="AQP45426"/>
        <property type="gene ID" value="RPIT_11965"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92472">
        <property type="protein sequence ID" value="SDY92472"/>
        <property type="gene ID" value="SAMN05428934_10682"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11965"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544480" evidence="1">
        <location>
            <begin position="40"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY92472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="100" mass="10566" checksum="57210E919517880A" modified="2017-04-12" version="1">MFAAASVLGVLAGWPLGHRLAFASLCSSLAVQQFGGSLAAPGWGDISDWWRCVKLRAADGDVSAAGKLERYGFLDDLVPKHRVHGVRRAEGTFASASDAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHB3</accession>
    <name>A0A1Q2CHB3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_12150</name>
        <name evidence="2" type="ORF">SAMN05428934_10646</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY91674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45463">
        <property type="protein sequence ID" value="AQP45463"/>
        <property type="gene ID" value="RPIT_12150"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY91674">
        <property type="protein sequence ID" value="SDY91674"/>
        <property type="gene ID" value="SAMN05428934_10646"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12150"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY91674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="264" mass="28895" checksum="B3C9E193ABD76167" modified="2017-04-12" version="1">MSRPALLELIVRGDFEQTRQVLLAEPKIDRATATAVGRLRREMAKAPAGESSAYWEGELSDGHWDAVTVAHLASLPASKAAGVSSVSRRAASTLPEIFQGELAAIVDGWASLYQRNPRNWDRNGHYPIMFEWVGRGLIPAPVHDGAVNLWLEFATRIVHPLSPPGAGEPQDWTVPTPQACPALYVVTLPLLFQAAVKPGLGAAALDHQSGGQVQDLVCHLVESGVWDHTETVSRLEAAMLLPDRANAFQQRWLKQLEQRLAELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHC2</accession>
    <name>A0A1Q2CHC2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 17">Aspartokinase</fullName>
            <ecNumber evidence="7 17">2.7.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">RPIT_12215</name>
        <name evidence="21" type="ORF">SAMN05428934_10633</name>
    </gene>
    <organism evidence="20 22">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="20 22" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 22">RP1T</strain>
        </source>
    </reference>
    <reference evidence="21 23" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 23">RP1</strain>
        </source>
    </reference>
    <reference evidence="20" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>ATP + L-aspartate = 4-phospho-L-aspartate + ADP</text>
            <dbReference type="Rhea" id="RHEA:23776"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 18">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 18">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 18">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 17">Belongs to the aspartokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.4" evidence="7 17"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY91400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12215"/>
    <dbReference type="EnsemblBacteria" id="AQP45473">
        <property type="protein sequence ID" value="AQP45473"/>
        <property type="gene ID" value="RPIT_12215"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY91400">
        <property type="protein sequence ID" value="SDY91400"/>
        <property type="gene ID" value="SAMN05428934_10633"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12215"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00015"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00461"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04261">
        <property type="entry name" value="AAK_AKii-LysC-BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041740">
        <property type="entry name" value="AKii-LysC-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005260">
        <property type="entry name" value="Asp_kin_monofn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001341">
        <property type="entry name" value="Asp_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018042">
        <property type="entry name" value="Aspartate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000726">
        <property type="entry name" value="Asp_kin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00657">
        <property type="entry name" value="asp_kinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00324">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 18" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="12 17 20" id="KW-0418">Kinase</keyword>
    <keyword evidence="15" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="11 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="19">
        <location>
            <begin position="270"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="7"/>
            <end position="10"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:30616"/>
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        <ligand>
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    <sequence length="424" mass="45051" checksum="754FEE5E3A922FAB" modified="2017-04-12" version="1">MGRIVQKFGGSSVADAESIKRVARRIARTRSEGHDVIIVISAMGDTTDELMDLALQVSPRPKSRELDMLLTTGERQSAALLAMALSDLGVDAVSYTGSQAGIITTPTHGNARIIDITPGRVEKSLAEDNVVIVAGFQGVAQTTKDVTTLGRGASDTTAVALAASLGADYCEIYSDVDGVYTADPRIVPSARRIAEIGYEDMMEMAASGAKILHLRCVEYARREGVPVHVRSSFTDKQGTWVKSQDEITKDEAMEEAIITGVAHDRGEAKVTIVGVPDKVGEAARIFRAIADKEINIDMIVQNVSRLSDAATDISFTLPMTDGALAMEALEAVRDEVGFEELLYDDQIGKVSVVGVGMRSHPGVSATFFDALAKANVNLQMISTSEIRISVIVSADDVDAAVRASHSAFGLDADEAATVYAGTGR</sequence>
</entry>
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <sequence length="286" mass="30961" checksum="E58F0F738E92B61B" modified="2017-04-12" version="1">MKIAGAPICWGVCEVPGWGYQMAPERVLTEMREIGLTATEFGPQGWLPVDAEERAAVVREYGLKPVGSFFLAVMHDPDFDPIGMVEQELHAFEVAGGEFLVLAADSGREGYDDRPVLDEAGWQTLFTNLSRIREACAAKGVTATLHPHWGTMVQNVDEVRRVLDNSTVGLCLDTGHLSAGGADVVQLVRDYADRVDIVHAKDIRKDLTDKLLTGELSWSEGIKAGMFTPIGDGDIDFPTIVGLLNEAGFDGYFVLEQDIMLDEEPPADDGPVANAAKSFAALQALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-methylmalonyl-CoA = succinyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:22888"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:57326"/>
            <dbReference type="EC" id="5.4.99.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Metabolic intermediate metabolism; propanoyl-CoA degradation; succinyl-CoA from propanoyl-CoA: step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the methylmalonyl-CoA mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.2" evidence="6"/>
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        <property type="protein sequence ID" value="AQP45538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY79687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12590"/>
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    </dbReference>
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        <property type="protein sequence ID" value="SDY79687"/>
        <property type="gene ID" value="SAMN05428934_104168"/>
    </dbReference>
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        <property type="reaction ID" value="UER00910"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="term" value="F:cobalamin binding"/>
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        <property type="project" value="UniProtKB-EC"/>
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        <property type="term" value="P:lactate fermentation to propionate and acetate"/>
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        <property type="entry name" value="Cbl-dep_enz_cat"/>
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        <property type="entry name" value="MeMalonylCoA_mutase_a/b_cat"/>
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            <begin position="365"/>
            <end position="390"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00008465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011870"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00012398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY79687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="623" mass="65977" checksum="4F2296F55078ED86" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHI8</accession>
    <name>A0A1Q2CHI8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Probable phosphoglycerate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_12520</name>
        <name evidence="2" type="ORF">SAMN05428934_104182</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY80075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12520"/>
    <dbReference type="EnsemblBacteria" id="AQP45525">
        <property type="protein sequence ID" value="AQP45525"/>
        <property type="gene ID" value="RPIT_12520"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY80075">
        <property type="protein sequence ID" value="SDY80075"/>
        <property type="gene ID" value="SAMN05428934_104182"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12520"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY80075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="199" mass="21579" checksum="F48DCDE4394A536A" modified="2017-04-12" version="1">MRLILIRHGETASNVARALDTAHPGAPLNETGLAQAEALVRALAHEQIDALYASTLTRAQQTAAPLAAARGLEAVILEGIHEIAAGVEEMNTDWTAYVDMLNSWAPDNLDVGLEGGETAREFLTRFTNAVTSIERHGHDNVALVSHGAALRVWSISQDPDFGAHNAPPLRNTQWIVLNGTSSEGWEIERWGDFQRELAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHS8</accession>
    <name>A0A1Q2CHS8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Predicted oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13380</name>
        <name evidence="3" type="ORF">SAMN05428934_10411</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY75258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13380"/>
    <dbReference type="EnsemblBacteria" id="AQP45678">
        <property type="protein sequence ID" value="AQP45678"/>
        <property type="gene ID" value="RPIT_13380"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY75258">
        <property type="protein sequence ID" value="SDY75258"/>
        <property type="gene ID" value="SAMN05428934_10411"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13380"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY75258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="324" mass="35734" checksum="BEFF21BDD0500805" modified="2017-04-12" version="1">MQYTKLGRTGLKVSRLVLGTMNFGPETSEEDAHAIMSRALDEGINFFDTANGYGGKGHRGRTEEIIGRWFDKTGRRDEVVLGTKVYGGLTEDEKPNFSRLSAVNVRRSAIGSLKRLRTDHIDLYQMHHVDRETPWDEVWQSMDRLVAEGDIVYVGSSNFAGWHIAAATEAARRRGSLGLVSEQSLYNLAARTVELEVLPAARHYGLGVIPWSPLGGGLLGGVLRKLDEGRRASAGIASQVEEKRDQLQQWEDFCDELGEKPGDVALAWLLHQDGVTGPIIGPRTMEQLESALHALEISLDDDALRRLDEIFPGPGGSAPEAYAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHW3</accession>
    <name>A0A1Q2CHW3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13480</name>
        <name evidence="4" type="ORF">SAMN05428934_111103</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ13436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_076061689.1">
        <property type="nucleotide sequence ID" value="NZ_FNPU01000011.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45697">
        <property type="protein sequence ID" value="AQP45697"/>
        <property type="gene ID" value="RPIT_13480"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ13436">
        <property type="protein sequence ID" value="SDZ13436"/>
        <property type="gene ID" value="SAMN05428934_111103"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13480"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544521" evidence="2">
        <location>
            <begin position="28"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ13436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="70" mass="7168" checksum="F4622800425ABA26" modified="2017-04-12" version="1">MTPTKRIAALVAAAAALLAVTAVPAGAGEPSGRHFAEHVRMHASETGFSGTHNPGVMHQGFAGWDAHHNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHW9</accession>
    <name>A0A1Q2CHW9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Disulfide bond formation protein DsbA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_13325</name>
        <name evidence="2" type="ORF">SAMN05428934_10422</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY75584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13325"/>
    <dbReference type="EnsemblBacteria" id="AQP45670">
        <property type="protein sequence ID" value="AQP45670"/>
        <property type="gene ID" value="RPIT_13325"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY75584">
        <property type="protein sequence ID" value="SDY75584"/>
        <property type="gene ID" value="SAMN05428934_10422"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13325"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY75584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="200" mass="22115" checksum="A26807B058DE2B1B" modified="2017-04-12" version="1">MTTVVDFWFDPTCPFAWMTSRWMLEVEKVRDVQTVFHVMSLSVLNEGRDLPEDYRRMLDGAWVPARAALLVEQRHGSEKLREFYTEIGTRFHPGGEANTPETVAAALAAVGADADIIDVAQTDTIDDDLRRSHNEGMEPVGDEVGTPVIRINGMSLFGPVISPAPKGEEAGDLFDGVAKVTAYPGFFELKRSRTVGPIFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHX1</accession>
    <name>A0A1Q2CHX1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L34</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmH</name>
        <name evidence="7" type="ORF">RPIT_13600</name>
        <name evidence="8" type="ORF">SAMN05428934_11179</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL34 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ13028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13600"/>
    <dbReference type="EnsemblBacteria" id="AQP45718">
        <property type="protein sequence ID" value="AQP45718"/>
        <property type="gene ID" value="RPIT_13600"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ13028">
        <property type="protein sequence ID" value="SDZ13028"/>
        <property type="gene ID" value="SAMN05428934_11179"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_L34"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
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    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021229"/>
        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ13028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="45" mass="5341" checksum="8321662AB89C8A9D" modified="2017-04-12" version="1">MSKRTFQPSNRRRSRTHGFRTRMRTRAGRAILAARRRKGRVELSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHY2</accession>
    <name>A0A1Q2CHY2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA topoisomerase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="3">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_13670</name>
        <name evidence="10" type="ORF">SAMN05428934_11165</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type II topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13670"/>
    <dbReference type="EnsemblBacteria" id="AQP45728">
        <property type="protein sequence ID" value="AQP45728"/>
        <property type="gene ID" value="RPIT_13670"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12796">
        <property type="protein sequence ID" value="SDZ12796"/>
        <property type="gene ID" value="SAMN05428934_11165"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034335">
        <property type="term" value="F:DNA negative supercoiling activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GyrA/parC_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035516">
        <property type="entry name" value="Gyrase/topoIV_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
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        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
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        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03989">
        <property type="entry name" value="DNA_gyraseA_C"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101904">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="TOP4c" evidence="8">
        <location>
            <begin position="21"/>
            <end position="479"/>
        </location>
    </feature>
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        <location>
            <begin position="838"/>
            <end position="872"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ12796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="872" mass="96033" checksum="DDE76BF600096280" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI09</accession>
    <name>A0A1Q2CI09_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycosyltransferase involved in cell wall bisynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_13805</name>
        <name evidence="6" type="ORF">SAMN05428934_11139</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13805"/>
    <dbReference type="EnsemblBacteria" id="AQP45747">
        <property type="protein sequence ID" value="AQP45747"/>
        <property type="gene ID" value="RPIT_13805"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12318">
        <property type="protein sequence ID" value="SDZ12318"/>
        <property type="gene ID" value="SAMN05428934_11139"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13805"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
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        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="4">
        <location>
            <begin position="24"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="3">
        <location>
            <begin position="186"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDZ12318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="386" mass="42131" checksum="CC30203D6434525B" modified="2017-04-12" version="1">MTDQDAPQVPPLRVLWLIKGLGPGGAERLLVSFARLVGRDSLSVEVGYVRPDKTQLVAELASLGVTSRPLSGDGHHWIATLRKLLATGGFDVVHAHSPLLAGVVRLLVRTLPQKTRPKVATTEHNEWESYARRTRLLNAVTAPLDSHRWAVSRRVRASMWPWVGKGTEVLIQGIEFDRFDAAADARQRIRRELGIPHDAVVAVSVANLRRPKDYPNLLRATGVARLEIPNFTVLVLGQGPLKEEIEGLHAELGLGDSVRFLGFRSDVADILAASDIFVIASAYEGGPLSLIEAMRSGLPSVATDVGFVSDVIEPGVHGLIVPTRNHRELAKAFVTLCRDGDARAAMGRAARSVSGRFDIRETVERQMEVYRQLAGKASSLNTSRND</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI32</accession>
    <name>A0A1Q2CI32_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13970</name>
        <name evidence="3" type="ORF">SAMN05428934_1114</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ11573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45772">
        <property type="protein sequence ID" value="AQP45772"/>
        <property type="gene ID" value="RPIT_13970"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ11573">
        <property type="protein sequence ID" value="SDZ11573"/>
        <property type="gene ID" value="SAMN05428934_1114"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13970"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ11573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="123" mass="12993" checksum="AA7F620FBCB88F83" modified="2017-04-12" version="1">MTSERSHAAYRAPDNVAWIDGAALDMGEELYLTRMPDGHSVLLAGSARLIWLVAAEGGDVLPGVAELVGMPPSEIADDVAQFLDDLVSRGLLTRDHRPSRNRGEQIPMQPTLGGGAPCGGVCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI46</accession>
    <name>A0A1Q2CI46_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Biotin carboxylase</fullName>
            <ecNumber evidence="2">6.3.4.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">RPIT_14115</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="6.3.4.14" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14115"/>
    <dbReference type="EnsemblBacteria" id="AQP45798">
        <property type="protein sequence ID" value="AQP45798"/>
        <property type="gene ID" value="RPIT_14115"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14115"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013537">
        <property type="entry name" value="AcCoA_COase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08326">
        <property type="entry name" value="ACC_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="13">
        <location>
            <begin position="2"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="12">
        <location>
            <begin position="128"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="11">
        <location>
            <begin position="588"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="14">
        <location>
            <begin position="1536"/>
            <end position="1837"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="AQP45798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="1840" mass="197932" checksum="7BBDC68582CD94D4" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI50</accession>
    <name>A0A1Q2CI50_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Alanine or glycine:cation symporter, AGCS family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Sodium:alanine symporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_14085</name>
        <name evidence="10" type="ORF">SAMN05428934_1173</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000017">
        <property type="protein sequence ID" value="SDZ20747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14085"/>
    <dbReference type="EnsemblBacteria" id="AQP45792">
        <property type="protein sequence ID" value="AQP45792"/>
        <property type="gene ID" value="RPIT_14085"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ20747">
        <property type="protein sequence ID" value="SDZ20747"/>
        <property type="gene ID" value="SAMN05428934_1173"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14085"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015655">
        <property type="term" value="F:alanine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001463">
        <property type="entry name" value="Na/Ala_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30330">
        <property type="entry name" value="PTHR30330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01235">
        <property type="entry name" value="Na_Ala_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00175">
        <property type="entry name" value="NAALASMPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00835">
        <property type="entry name" value="agcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00873">
        <property type="entry name" value="NA_ALANINE_SYMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="242"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="305"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="349"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="393"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ20747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="478" mass="50369" checksum="8880EF323CD67437" modified="2017-04-12" version="1">METITNWLDGFNGQIYSWILIPVLLGAGVWFTVATRGMQFRLIGRMFSVLGGSRHSADKDGGISSFQAFAIGLASRVGTGNIAGVAIAITLGGPGAVFWMWVVALLGMATAFIEATLAQIFKMPWGDGTFRGGPAFYIWRGLKSWKWGAVFAVVLLFTYGIAFQMVQANTIATTVQSTFGVDTWITALIIAALTGAAIIGGIRSVAKVSEVLAPAMALIYVLIALVVIALNLDQIGFVFSEIIQSAFGLNEAFAGTAGGITAAIMNGVKRGLYSNEAGMGSAPNAASTATTIHPARQGLIQSFGVFVDTMIVCSATAFIVLSSGVYTPGQDLEGATLTQSGVAAALGDWMAPVMVVLISVFAFSTLIGNYAYAEVNLDYLTKDRPGSDLTLKIVVVIATFVGGIAKLSSVWVLADTSMFFMAIINLVAIILLGKWAFAALRDYEANPEGRFVAVGNDHLPGVLDTEIWVADPPKAAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI66</accession>
    <name>A0A1Q2CI66_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">T2SSF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_14235</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14235"/>
    <dbReference type="EnsemblBacteria" id="AQP45819">
        <property type="protein sequence ID" value="AQP45819"/>
        <property type="gene ID" value="RPIT_14235"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14235"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="7">
        <location>
            <begin position="109"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="286" mass="30285" checksum="EE0AE85839F67402" modified="2017-04-12" version="1">MEVMLAALAGSMIVAGAIAVVVGARRAVREPSTALSTGLWTRIATLWRGLPRAHRLWVVVSVGAGVLAAVASGWLLALVLLPAVAIVVPLLLSAPPNREVEVLAGLDRWVRVVATSLSSGKSIRDAVFSTRHQVPDVLADPVARLCTRLDQRWTMRDALFAMADELESADADAVVAALAIAASKGGAGARATLGALSDSIQDRLRALREIASERAKPRAVVRQVTLITLTVLAAAILFNGRFFEPYTTPLGQIIAVALAATYLGCLLMLRRLTVPPPAPRFLRSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIE1</accession>
    <name>A0A1Q2CIE1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_14555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45877">
        <property type="protein sequence ID" value="AQP45877"/>
        <property type="gene ID" value="RPIT_14555"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14555"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007497">
        <property type="entry name" value="DUF541"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04402">
        <property type="entry name" value="SIMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="222" mass="23898" checksum="7A77DE376AE5E566" modified="2017-04-12" version="1">MMQITVQGEATASFPPERATVHLELGFEGPDKAAALQRATQLANELGSHLERLAQMTPSPTTWSAILPIGTRSWRPHSNDGAVLPLRYAASCRAKVKFSDFRALAQFIDQWGGVDGVSVRQVEWTLTERAKRKEEEAVLARAVEVARARAQTIATAAGSGQVRVIDIADPGLLGQGLVAQESHGSAAMMRSLYDGGAQGDGVDLRPEDVDLVARVHARFTTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIH3</accession>
    <name>A0A1Q2CIH3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Xylose isomerase</fullName>
            <ecNumber evidence="4 11">5.3.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">RPIT_14745</name>
        <name evidence="15" type="ORF">SAMN05428934_10971</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1T</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1</strain>
        </source>
    </reference>
    <reference evidence="14" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>alpha-D-xylose = alpha-D-xylulofuranose</text>
            <dbReference type="Rhea" id="RHEA:22816"/>
            <dbReference type="ChEBI" id="CHEBI:28518"/>
            <dbReference type="ChEBI" id="CHEBI:188998"/>
            <dbReference type="EC" id="5.3.1.5"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the xylose isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.5" evidence="4 11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14745"/>
    <dbReference type="EnsemblBacteria" id="AQP45907">
        <property type="protein sequence ID" value="AQP45907"/>
        <property type="gene ID" value="RPIT_14745"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05943">
        <property type="protein sequence ID" value="SDZ05943"/>
        <property type="gene ID" value="SAMN05428934_10971"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14745"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009045">
        <property type="term" value="F:xylose isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013453">
        <property type="entry name" value="XylA_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001998">
        <property type="entry name" value="Xylose_isomerase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00688">
        <property type="entry name" value="XYLOSISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02631">
        <property type="entry name" value="xylA_Arthro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51415">
        <property type="entry name" value="XYLOSE_ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0859">Xylose metabolism</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="13">
        <location>
            <begin position="36"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="AQP45907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="SDZ05943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="387" mass="42748" checksum="655C976672828286" modified="2017-04-12" version="1">MQDHKFSFGLWTVGWQGTDPFGGNTRRAFEPWEYADKLAELGAWGITFHDNDVYDFDADEATAKARVSQLKDAADKAGLVVEMVTTNTFSHPIFKDGGLTSNDRGVRRFGLKKILNAVDIAAEVGATTFVMWGGREGAEYDSSKDYFAAHARYAEGLDTVAGYIKEQGYDLRIGLEPKPNEPRGDILLPTIGHALGLIATLEHGDIVGLNPEVGHEQMANLNFTQGIALALYCDKLFHIDLNGQRGLKYDQDLAFGHGDLMSSFFTVDLLVNGFPASPDAPRYTGPIHFDYKPSRTEGIEGIWDSAKANMETFSLLADRAKSFREDPAVQELMREASIFELTEPTLAEGETVADLRQAEMPDPAAKGEREYRFVELQQAAMRHLLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIL9</accession>
    <name>A0A1Q2CIL9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="5">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP cyclohydrolase I</fullName>
            <shortName evidence="5">GTP-CH-I</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">folE</name>
        <name evidence="7" type="ORF">RPIT_01570</name>
        <name evidence="8" type="ORF">SAMN05428934_10862</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17473"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="EC" id="3.5.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homopolymer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01570"/>
    <dbReference type="EnsemblBacteria" id="AQP45961">
        <property type="protein sequence ID" value="AQP45961"/>
        <property type="gene ID" value="RPIT_01570"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02110">
        <property type="protein sequence ID" value="SDZ02110"/>
        <property type="gene ID" value="SAMN05428934_10862"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01570"/>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035998">
        <property type="term" value="P:7,8-dihydroneopterin 3'-triphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="PTHR11109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP_cyclohydroI" evidence="6">
        <location>
            <begin position="10"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ02110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="188" mass="20555" checksum="9B8EAD0C9A2881CF" modified="2017-04-12" version="1">MAVDHQRAIAAVRELLAAVGEDPDRDGLLETPDRVARSWAEMLAGHGADPADLLAKTFDIDHDEMVLVKDIRFVSMCEHHLLPFTGVAHIGYIPSPERGVTGLSKLARLVELFARRLQVQERITSQIAEALVEHLDAHGVIVVLEAEHTCMTMRGVKKPGSMTVTSAVRGQLRVPATRAEAMSLILGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIQ2</accession>
    <name>A0A1Q2CIQ2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Peptidase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="13">RIP metalloprotease RseP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_04540</name>
        <name evidence="13" type="ORF">SAMN05428934_101514</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M50B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04540"/>
    <dbReference type="EnsemblBacteria" id="AQP46018">
        <property type="protein sequence ID" value="AQP46018"/>
        <property type="gene ID" value="RPIT_04540"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37242">
        <property type="protein sequence ID" value="SDY37242"/>
        <property type="gene ID" value="SAMN05428934_101514"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04540"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004387">
        <property type="entry name" value="Pept_M50_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42837">
        <property type="entry name" value="PTHR42837"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="13" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M50" evidence="10">
        <location>
            <begin position="13"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ_6" evidence="11">
        <location>
            <begin position="175"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP46018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY37242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="428" mass="46433" checksum="8D5A5A726DCD4261" modified="2017-04-12" version="1">MTVLLTVLFALLFFALIMASIALHEVGHLVPAKLFGVKVTQYFVGFGKTLWSFRRGETEYGIKAFPLGGYVRLVGMYPPQRHRADAKGRLERLADQARAYEWEDIRPQDDGRLFFQKKTWQKVIVMLAGPAMNVLIAFVLFLGINVFHGSYEPTLTVEQVSECAVRADRADQTCTQGDPSTPAALAGVSTGDVLVSFNGTELTSWEQMGDLIRDNRDQPATVVVERDGELVELPTVNTVLNYVPDRLDPTRMVEAGFFGVSPATALVRGGPVATAQQMWTLTKQSAVALASFPVRIYNVAADLVTGQPRDVNSPLSIVGASRVAGEIGTTDSLEATEKVVTWVSLLAAVNLFVALLNLVPLLPLDGGHVAGAVYEWLRRVLARMSGRPDPGPVDTAKGLPITYLVGGFLLLGGVVLILADIISPIRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIW8</accession>
    <name>A0A1Q2CIW8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AraC family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Effector-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07190</name>
        <name evidence="3" type="ORF">SAMN05428934_1106</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP46069">
        <property type="protein sequence ID" value="AQP46069"/>
        <property type="gene ID" value="RPIT_07190"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08090">
        <property type="protein sequence ID" value="SDZ08090"/>
        <property type="gene ID" value="SAMN05428934_1106"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07190"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010499">
        <property type="entry name" value="AraC_E-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029442">
        <property type="entry name" value="GyrI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06445">
        <property type="entry name" value="GyrI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00871">
        <property type="entry name" value="AraC_E_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AraC_E_bind" evidence="1">
        <location>
            <begin position="16"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ08090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="174" mass="18715" checksum="188579E9AD8F0C11" modified="2017-04-12" version="1">MTSVGPTPYYLSPQRTDLDFLDAPEIPTVVRKFVDYPLSEMATAMDGTVSVLFALLETEGIHPTGPPFSLYEHMSGETATFEIGVPVDRRLDGPVTAAPGVVIEGSVLPGGTLATISHIGSYDRLGDAWGAFMEAVTQAGKTAELPFWEIYLTEPGPGVDPETMRTDLVTRIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIW9</accession>
    <name>A0A1Q2CIW9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF305 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_08465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08465"/>
    <dbReference type="EnsemblBacteria" id="AQP46088">
        <property type="protein sequence ID" value="AQP46088"/>
        <property type="gene ID" value="RPIT_08465"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08465"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005183">
        <property type="entry name" value="DUF305"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03713">
        <property type="entry name" value="DUF305"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="DUF305" evidence="2">
        <location>
            <begin position="93"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="147" mass="16766" checksum="51F3D0A4ECE19EDE" modified="2017-04-12" version="1">MSMYWKFGGILLVNLFLMWALSMSMVRSIDHFYFNPSNLYMAVLMVAAMAVLMTVGMWSMLKNRTLNIILLVGFLALFLAAFFMGRSEVGVGDEGFLKSMIPHHSRAILVCQEASITDPEIEQLCVEIIDAQQKEIAQMKEILERYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ50</accession>
    <name>A0A1Q2CJ50_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Flavin_Reduct domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11005"/>
    <dbReference type="EnsemblBacteria" id="AQP46132">
        <property type="protein sequence ID" value="AQP46132"/>
        <property type="gene ID" value="RPIT_11005"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11005"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin_Reduct" evidence="1">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="148" mass="15724" checksum="5D5F5B1499CB2D95" modified="2017-04-12" version="1">MARVPAPVTVITTMVDGVPIGTTVSAFASLSIAPPMAFLALDNRGGMIGRVRDAGRIGINILAAGQEEIAIRFARRDLPDRFAGLAWHDDHGLPRIDGAVAWLRCEQLQLLPGGDHTVILAHVDDAATAGDHSLGYHLRTFRDVGPAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ93</accession>
    <name>A0A1Q2CJ93_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Oxaloacetate decarboxylase gamma chain</fullName>
            <ecNumber evidence="5">7.2.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_10240</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:57724"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="EC" id="7.2.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the OadG family.</text>
    </comment>
    <dbReference type="EC" id="7.2.4.2" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10240"/>
    <dbReference type="EnsemblBacteria" id="AQP46120">
        <property type="protein sequence ID" value="AQP46120"/>
        <property type="gene ID" value="RPIT_10240"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10240"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015451">
        <property type="term" value="F:decarboxylation-driven active transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015081">
        <property type="term" value="F:sodium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005899">
        <property type="entry name" value="Na_pump_deCOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04277">
        <property type="entry name" value="OAD_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01195">
        <property type="entry name" value="oadG_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0915">Sodium</keyword>
    <keyword evidence="5" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP46120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="124" mass="13134" checksum="1005A89CA23B9E40" modified="2017-04-12" version="1">MDLLLWGLMMMAVGMGTVFALLILLMLVLKAIARLDRSPAAVAATPPPPALVEGDQPGPPAVRIVADGLDETQVAAITVAVIAHAENRRRLAAPETRVAAPGSQLFASRWLTVGRGRQHTPGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ99</accession>
    <name>A0A1Q2CJ99_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_14175</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14175"/>
    <dbReference type="EnsemblBacteria" id="AQP46187">
        <property type="protein sequence ID" value="AQP46187"/>
        <property type="gene ID" value="RPIT_14175"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14175"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024671">
        <property type="entry name" value="Atg22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11700">
        <property type="entry name" value="ATG22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="243"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="332"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="369"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP46187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="451" mass="47953" checksum="BF3C853A69DD5FD5" modified="2017-04-12" version="1">MPGLTPGALSATEAPRSRVISWALWDWGTQPFATVITTFVFSVYLTSSAFGPKDEVTMKLAWATGLAGLLIALLAPVLGQGADRTGKRMFHLRWQTWVLAAICAAMYFVAPAPEYFLLGAALLGAGNVISEIANVNYYAAIDQVSTPRNVGRVSGLGWGLGYLGGIAILLLIIAVRGSEFGPDDVRVAMLFCGAWTLVFTVPIFVALKDRRPDHVAPKIGILGSYRELFRSIKWLARTAPNTLFFYIAAALFRDGLAGVFTFGGVLAAGTFGFAFSEVVMFGVAANVIAGVATIGFGLIDDRIGPKTVILTSLVSLIALGTAIFIFHDGGKPVFWALGLAMCIFVGPAQSASRSFLARLIPEGHSGEMFGLYATTGRAVSFLAPTMFGVAIAVGATFTDSAEESAQHWGILGIVLVLAVGFVFALFVKDPSKHPVVAVPPEVRSMDPRRHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJA4</accession>
    <name>A0A1Q2CJA4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidoglycan bridge formation protein FemAB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FemABX family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13085"/>
    <dbReference type="EnsemblBacteria" id="AQP46163">
        <property type="protein sequence ID" value="AQP46163"/>
        <property type="gene ID" value="RPIT_13085"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13085"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016755">
        <property type="term" value="F:aminoacyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044038">
        <property type="term" value="P:cell wall macromolecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003447">
        <property type="entry name" value="FEMABX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02388">
        <property type="entry name" value="FemAB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51191">
        <property type="entry name" value="FEMABX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="373" mass="41758" checksum="F927F03C86C921E6" modified="2017-04-12" version="1">MTCRPISAEQHLAHIGQRGSASFLQTPAWAKVKSEWRGESVGFFDGDDLVGVALVLYRQLPKLKRYLAYLPEGPVLDWARPDVAEALQAFVTYAKKRKAFAVRIGPTLVHRRWLAPTIKDAVADDDVTRLSDVTPDETTLLGTRVRNLLLHGGWVTDETGEGFAAGQPMFNFQLPLRHDDGSQKSEDELLKGMNQQWRRNIKKAAKEGVVVRQGSREDLAAFHRIYLETAARDGFTGRALSYFETMWDALRAEDPERMKVYLAEHDGDLVAATTMVQVGEHAWYSYGASTNAKREVRGSNAVQWQMIRDANAAGCAVYDLRGITEGVGKDDPEIGLIQFKVGTGGEAVAYLGEWDYAINKPLYFAFTQYLKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBC4</accession>
    <name>A0A1Q2CBC4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uroporphyrinogen-III C-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_00040</name>
        <name evidence="9" type="ORF">SAMN05428934_10937</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.107" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00040"/>
    <dbReference type="EnsemblBacteria" id="AQP43410">
        <property type="protein sequence ID" value="AQP43410"/>
        <property type="gene ID" value="RPIT_00040"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05313">
        <property type="protein sequence ID" value="SDZ05313"/>
        <property type="gene ID" value="SAMN05428934_10937"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00040"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004851">
        <property type="term" value="F:uroporphyrin-III C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11642">
        <property type="entry name" value="SUMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006366">
        <property type="entry name" value="CobA/CysG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01469">
        <property type="entry name" value="cobA_cysG_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="7">
        <location>
            <begin position="9"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP43410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ05313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="252" mass="25922" checksum="9DFE5961D6BEE80A" modified="2017-04-12" version="1">MRFEFAPGTVVLVGGGPGDPGLMTVAGLSAIQQADVIVHDRLGPLELLDEAADGAEVINVGKIPRGAYTPQEEINRLLVDRAQQGLRVVRLKGGDNYVFGRGGEEWLACAEAGVPVRVIPGVTSAVSVPAMAGIPVTHRSLSQGFCVVSGHVAPDDERSAVDWGALARCGLTIVILMGVHNLNHIADALIAGGMEPGTAAAVVADGTTPGQRTIRSRLDRVSNEAAGADVRPPAIVVVGAVAGLTLNAREPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBE9</accession>
    <name>A0A1Q2CBE9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glyoxalase_6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00185</name>
        <name evidence="4" type="ORF">SAMN05428934_1097</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ04648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00185"/>
    <dbReference type="EnsemblBacteria" id="AQP43434">
        <property type="protein sequence ID" value="AQP43434"/>
        <property type="gene ID" value="RPIT_00185"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ04648">
        <property type="protein sequence ID" value="SDZ04648"/>
        <property type="gene ID" value="SAMN05428934_1097"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00185"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyoxalase_6" evidence="2">
        <location>
            <begin position="25"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ04648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="66" mass="7303" checksum="46F2AE4D369D1E67" modified="2017-04-12" version="1">MTGSVGPQEPRPPRRGPDQPKDWDVMRAKAAKLVAAGADVVEEFRQPPQGEWIVMEDPEGNEFCVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBG5</accession>
    <name>A0A1Q2CBG5_9ACTN</name>
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        <submittedName>
            <fullName evidence="8">LysE type translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_00275</name>
        <name evidence="8" type="ORF">SAMN05428934_1059</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY83620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00275"/>
    <dbReference type="EnsemblBacteria" id="AQP43446">
        <property type="protein sequence ID" value="AQP43446"/>
        <property type="gene ID" value="RPIT_00275"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY83620">
        <property type="protein sequence ID" value="SDY83620"/>
        <property type="gene ID" value="SAMN05428934_1059"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00275"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="100"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY83620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="129" mass="13668" checksum="D88BFC830F5BDB56" modified="2017-04-12" version="1">MPTWFSLVGFLLAVTPLVMTPGASFTLVSAKGVSGDRRGAFQIILGTGLGILTHAVLAGLGLAVLVMQSAQAYAVVRLVGTAYLVGLVVWLLAKALLRREPDPTPGRQGRRPRHARNPWPPRTSPTSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
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            <fullName evidence="1">DUF1801 domain-containing protein</fullName>
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    </protein>
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="RPIT_00510"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF08818">
        <property type="entry name" value="DUF1801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1801" evidence="1">
        <location>
            <begin position="12"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="138" mass="15265" checksum="BCBF88B2F2D691BB" modified="2017-04-12" version="1">MLTVEALPERRKAQGQELLSLFASETGAHPQMWGPSIVGFGHVRYTYATGRSGEMPRVGFSPRKAALSLYGLTLYGSNEDLLERLGKHRVGKGCLYINKLDDIDLDVLRQLIRRGWAGSTENFSDTHDGTRIEALDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBT5</accession>
    <name>A0A1Q2CBT5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00980</name>
        <name evidence="2" type="ORF">SAMN05428934_105147</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00980"/>
    <dbReference type="EnsemblBacteria" id="AQP43569">
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        <property type="gene ID" value="RPIT_00980"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87350">
        <property type="protein sequence ID" value="SDY87350"/>
        <property type="gene ID" value="SAMN05428934_105147"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00980"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY87350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="209" mass="22884" checksum="B5AF0A1B8714D147" modified="2017-04-12" version="1">MAETTTTSSSSGTNKGLVVLLVLALAAAAFFAYQAAPTLPFLKDVVDRDSRTVASLSREEQVVLLSLGIQGIAERNEKSSVFGFDVPGSGRATFLQYEFNAKLGLEGKDVTIEPTGEDSFRITIPEFVFIGHDNPNFRLAAEDNGVLSWITPEADTVDMINNILDSEAQQEYIDSNEDILRDQAEVFYTSIIESVDPDVTLTFDFGQDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBX8</accession>
    <name>A0A1Q2CBX8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha-L-AF_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_01320</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 51 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01320"/>
    <dbReference type="EnsemblBacteria" id="AQP43623">
        <property type="protein sequence ID" value="AQP43623"/>
        <property type="gene ID" value="RPIT_01320"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01320"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046373">
        <property type="term" value="P:L-arabinose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010720">
        <property type="entry name" value="Alpha-L-AF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003305">
        <property type="entry name" value="CenC_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009784">
        <property type="entry name" value="DUF1349"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06964">
        <property type="entry name" value="Alpha-L-AF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02018">
        <property type="entry name" value="CBM_4_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07081">
        <property type="entry name" value="DUF1349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00813">
        <property type="entry name" value="Alpha-L-AF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-L-AF_C" evidence="4">
        <location>
            <begin position="757"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1128"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1135"/>
            <end position="1169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="1307" mass="143270" checksum="1704C7976E99AC11" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC02</accession>
    <name>A0A1Q2CC02_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DEAD/DEAH box helicase domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01420</name>
        <name evidence="4" type="ORF">SAMN05428934_10832</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP43639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01420"/>
    <dbReference type="EnsemblBacteria" id="AQP43639">
        <property type="protein sequence ID" value="AQP43639"/>
        <property type="gene ID" value="RPIT_01420"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01536">
        <property type="protein sequence ID" value="SDZ01536"/>
        <property type="gene ID" value="SAMN05428934_10832"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01420"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022307">
        <property type="entry name" value="Helicase_put_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018973">
        <property type="entry name" value="MZB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09369">
        <property type="entry name" value="DUF1998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03817">
        <property type="entry name" value="DECH_helic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="56"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="273"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ01536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="755" mass="82117" checksum="2F027DB5C239772A" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC32</accession>
    <name>A0A1Q2CC32_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Putative fluoride ion transporter CrcB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">crcB</name>
        <name evidence="10" type="ORF">RPIT_01535</name>
        <name evidence="11" type="ORF">SAMN05428934_10855</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Important for reducing fluoride concentration in the cell, thus reducing its toxicity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the CrcB (TC 9.B.71) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ01980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01535"/>
    <dbReference type="EnsemblBacteria" id="AQP43657">
        <property type="protein sequence ID" value="AQP43657"/>
        <property type="gene ID" value="RPIT_01535"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01980">
        <property type="protein sequence ID" value="SDZ01980"/>
        <property type="gene ID" value="SAMN05428934_10855"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01535"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903425">
        <property type="term" value="F:fluoride transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00454">
        <property type="entry name" value="CrcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003691">
        <property type="entry name" value="CrcB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259">
        <property type="entry name" value="PTHR28259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02537">
        <property type="entry name" value="CRCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP43657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDZ01980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="112" mass="11182" checksum="C6B78E0E1556B48E" modified="2017-04-12" version="1">MIWLIALAGGVGALARAGVDRLVTLRFPGWVATLAVNITGSFLIGVSATHLSGPVVGVVAAGFCGGFTTFSSACWQAARELGTRRVPFAVVYTGATVAGCLLAASLGLATGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC63</accession>
    <name>A0A1Q2CC63_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01735</name>
        <name evidence="3" type="ORF">SAMN05428934_10895</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01735"/>
    <dbReference type="EnsemblBacteria" id="AQP43687">
        <property type="protein sequence ID" value="AQP43687"/>
        <property type="gene ID" value="RPIT_01735"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02736">
        <property type="protein sequence ID" value="SDZ02736"/>
        <property type="gene ID" value="SAMN05428934_10895"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01735"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ02736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="253" mass="27063" checksum="89FF9A6CD82BB86F" modified="2017-04-12" version="1">MSKSWAVVTGASSGLGVAYAERMAADGANVVLVARSVDKMEKVAASLRAQHGVDTLVLAVDLTDRAARAELVELLKERDVSHLINNAGFGTINSFHEISEERILSELELNVVALTELSRAAVPGMLSRGRGAIINVSSTAAFQAIPEMAVYAAAKAYVLRFTSALWGELKTTGVRALAVCPGPTETEFFANAGRASAMRRRRTPEQVVDATFDALGRHRPFVVDGTINKVLAFTNRLVPVDLQVAVARHVATH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC64</accession>
    <name>A0A1Q2CC64_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphate ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Phosphate ABC transporter ATP-binding protein, PhoT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_01755</name>
        <name evidence="7" type="ORF">SAMN05428934_10899</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01755"/>
    <dbReference type="EnsemblBacteria" id="AQP43691">
        <property type="protein sequence ID" value="AQP43691"/>
        <property type="gene ID" value="RPIT_01755"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02820">
        <property type="protein sequence ID" value="SDZ02820"/>
        <property type="gene ID" value="SAMN05428934_10899"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01755"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015415">
        <property type="term" value="F:ATPase-coupled phosphate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03260">
        <property type="entry name" value="ABC_PstB_phosphate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015850">
        <property type="entry name" value="ABC_transpr_PstB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005670">
        <property type="entry name" value="Phosp_transpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423">
        <property type="entry name" value="PTHR43423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423:SF3">
        <property type="entry name" value="PTHR43423:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00972">
        <property type="entry name" value="3a0107s01c2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="5"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ02820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="259" mass="28672" checksum="73F2C0A4CC6D3DDA" modified="2017-04-12" version="1">MSKRIELNDLNIYYGKFHAVKDVNMVIEPRAVTAFIGSSGCGKSTVLRSINRMHEVIDGAYVTGEVLLDGVDLYAPNVDPVRVRRQIGMVFQRPNPFPTMSIRENTLAGARLNNSRLSKSEADELVEKSLRGANLWNEVKDRLDKPGSGLSGGQQQRLCIARAIAVSPDVILMDEPCSALDPISTLAIEDLIKELKETYTVVIVTHNMQQAARVSDSTAFFNLKEHGKPGELIEMGPTEKIFHNPDQKATEDYITGRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCA9</accession>
    <name>A0A1Q2CCA9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Maltose/maltodextrin transport system permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_02090</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02090"/>
    <dbReference type="EnsemblBacteria" id="AQP43749">
        <property type="protein sequence ID" value="AQP43749"/>
        <property type="gene ID" value="RPIT_02090"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02090"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030156">
        <property type="entry name" value="MalF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035277">
        <property type="entry name" value="MalF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032550">
        <property type="entry name" value="TM_PBP2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47314:SF1">
        <property type="entry name" value="PTHR47314:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16296">
        <property type="entry name" value="TM_PBP2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="291"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="423"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="492"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="292"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP43749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="524" mass="57133" checksum="1C1D1712A3D3751A" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCB2</accession>
    <name>A0A1Q2CCB2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02105"/>
    <dbReference type="EnsemblBacteria" id="AQP43752">
        <property type="protein sequence ID" value="AQP43752"/>
        <property type="gene ID" value="RPIT_02105"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02105"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="217" mass="23135" checksum="75F40DEE1A027CA3" modified="2017-04-12" version="1">MLALLQSAGVAMSVVDVADRLGMHKNSARFHLDALVDARYAERWAQPTGHQGRPPLLFSATDASPTLTNIHLLELTDVLFASFVAPAPDAAQRAAEAGRAWGASVARSDPDDGAASVDDLVGHLGQRGFTTVRDESTLTFTRCPFRTTVRPDILPLLCTMHKGFLDGYLEAGGTGVGAGPIDVGPFRCVCALNETEPPEATEFSQHPTTIDAPDKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCB4</accession>
    <name>A0A1Q2CCB4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitrate reductase subunit beta</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Respiratory nitrate reductase beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02135</name>
        <name evidence="3" type="ORF">SAMN05428934_10125</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY23045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02135"/>
    <dbReference type="EnsemblBacteria" id="AQP43758">
        <property type="protein sequence ID" value="AQP43758"/>
        <property type="gene ID" value="RPIT_02135"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY23045">
        <property type="protein sequence ID" value="SDY23045"/>
        <property type="gene ID" value="SAMN05428934_10125"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02135"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009325">
        <property type="term" value="C:nitrate reductase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008940">
        <property type="term" value="F:nitrate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042126">
        <property type="term" value="P:nitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029263">
        <property type="entry name" value="Nitr_red_bet_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038262">
        <property type="entry name" value="Nitr_red_bet_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006547">
        <property type="entry name" value="NO3_Rdtase_bsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13247">
        <property type="entry name" value="Fer4_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14711">
        <property type="entry name" value="Nitr_red_bet_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01660">
        <property type="entry name" value="narH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="1">
        <location>
            <begin position="7"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="1">
        <location>
            <begin position="177"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="1">
        <location>
            <begin position="210"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY23045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="523" mass="58827" checksum="26C91A3EF4F79A39" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCF2</accession>
    <name>A0A1Q2CCF2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_01960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01960"/>
    <dbReference type="EnsemblBacteria" id="AQP43725">
        <property type="protein sequence ID" value="AQP43725"/>
        <property type="gene ID" value="RPIT_01960"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01960"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="177" mass="18437" checksum="F4E1602E716E2E85" modified="2017-04-12" version="1">MRWLPSAPEADVVTRAEAEAAARQAAASIGIEAIDLGIHPRGDTAARMSVVGWNTWLWAESPSSTQWGTMSTSATAAGITVSLNASSSQVTWSMGDGATVSCGQGTRWTMAGTGGRNVPSPDCGYVYDSEGRYTVTASTDWSIDWSAAGYSGTIPLEVRRSAEVIVGEMQSVNLAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCG1</accession>
    <name>A0A1Q2CCG1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_02415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02415"/>
    <dbReference type="EnsemblBacteria" id="AQP43813">
        <property type="protein sequence ID" value="AQP43813"/>
        <property type="gene ID" value="RPIT_02415"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02415"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021426">
        <property type="entry name" value="DUF3073"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11273">
        <property type="entry name" value="DUF3073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="75" mass="8401" checksum="CC2F6460E48560DF" modified="2017-04-12" version="1">MGRGRAKAKQTRVARDLKYRAIDTDFASLERELRGDAFVDDTVSGADDAVHEIPDAYADLAGDDYDDDYDERRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCG4</accession>
    <name>A0A1Q2CCG4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphoribosylformylglycinamidine synthase subunit PurL</fullName>
            <shortName evidence="5">FGAM synthase</shortName>
            <ecNumber evidence="5">6.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Formylglycinamide ribonucleotide amidotransferase subunit II</fullName>
            <shortName evidence="5">FGAR amidotransferase II</shortName>
            <shortName evidence="5">FGAR-AT II</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Glutamine amidotransferase PurL</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Phosphoribosylformylglycinamidine synthase subunit II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">purL</name>
        <name evidence="9" type="ORF">RPIT_02015</name>
        <name evidence="10" type="ORF">SAMN05428934_1161</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FGAMS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000016">
        <property type="protein sequence ID" value="SDZ20112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02015"/>
    <dbReference type="EnsemblBacteria" id="AQP43735">
        <property type="protein sequence ID" value="AQP43735"/>
        <property type="gene ID" value="RPIT_02015"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ20112">
        <property type="protein sequence ID" value="SDZ20112"/>
        <property type="gene ID" value="SAMN05428934_1161"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02015"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00420">
        <property type="entry name" value="PurL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010074">
        <property type="entry name" value="PRibForGlyAmidine_synth_PurL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041609">
        <property type="entry name" value="PurL_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43555">
        <property type="entry name" value="PTHR43555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="2"/>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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</entry>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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            <dbReference type="PubMed" id="26869509"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.</text>
    </comment>
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        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL12 family.</text>
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        <property type="protein sequence ID" value="AQP43892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP43892">
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    </dbReference>
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        <property type="protein sequence ID" value="SDY27710"/>
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    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02910"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00368">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_L7/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_L7/L12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_L7/L12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_L7/L12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="PTHR45987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="SSF48300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00855">
        <property type="entry name" value="L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L12_N" evidence="6">
        <location>
            <begin position="5"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L12" evidence="5">
        <location>
            <begin position="66"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY27710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="132" mass="13456" checksum="B873D1B3C250FC99" modified="2017-04-12" version="1">MAKLTNEELLDAFKEMTLIELSEFVKLFEDTFGVTAAAPVAVAAAAAPAAGGDDAGADDEGGSDKVDVILTSGGDKKIAVIKEVRALTSLGLKEAKDLVEGAPKPVLEQVDKDTAAKAKEALEAAGGSVEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCS1</accession>
    <name>A0A1Q2CCS1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">30S ribosomal protein S17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsQ</name>
        <name evidence="6" type="ORF">RPIT_03085</name>
        <name evidence="7" type="ORF">SAMN05428934_101218</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY28812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03085"/>
    <dbReference type="EnsemblBacteria" id="AQP43923">
        <property type="protein sequence ID" value="AQP43923"/>
        <property type="gene ID" value="RPIT_03085"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY28812">
        <property type="protein sequence ID" value="SDY28812"/>
        <property type="gene ID" value="SAMN05428934_101218"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03085"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01345_B">
        <property type="entry name" value="Ribosomal_S17_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019984">
        <property type="entry name" value="Ribosomal_S17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_S17/S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019979">
        <property type="entry name" value="Ribosomal_S17_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="PTHR10744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03635">
        <property type="entry name" value="uS17_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00056">
        <property type="entry name" value="RIBOSOMAL_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 3 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY28812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="91" mass="10450" checksum="1CE880091288B089" modified="2017-04-12" version="1">MSEETTTAERSRRKVLSGVVVSDKMDKTIVVLVEDRVKHPLYGKVMTKSSRVKAHDENNDANTGDRVRVMETRPLSAQKRWRLVEIVERAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCS9</accession>
    <name>A0A1Q2CCS9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutamate--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glutamyl-tRNA synthetase</fullName>
            <shortName evidence="8">GluRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gltX</name>
        <name evidence="12" type="ORF">RPIT_03000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03000"/>
    <dbReference type="EnsemblBacteria" id="AQP43907">
        <property type="protein sequence ID" value="AQP43907"/>
        <property type="gene ID" value="RPIT_03000"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03000"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00808">
        <property type="entry name" value="GluRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00022">
        <property type="entry name" value="Glu_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045462">
        <property type="entry name" value="aa-tRNA-synth_I_cd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020751">
        <property type="entry name" value="aa-tRNA-synth_I_codon-bd_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008925">
        <property type="entry name" value="aa_tRNA-synth_I_cd-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004527">
        <property type="entry name" value="Glu-tRNA-ligase_bac/mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033910">
        <property type="entry name" value="GluRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19269">
        <property type="entry name" value="Anticodon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48163">
        <property type="entry name" value="SSF48163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00464">
        <property type="entry name" value="gltX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="8"/>
            <end position="323"/>
        </location>
    </feature>
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        <location>
            <begin position="344"/>
            <end position="482"/>
        </location>
    </feature>
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        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
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            <begin position="253"/>
            <end position="257"/>
        </location>
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            <position position="256"/>
        </location>
        <ligand>
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        </ligand>
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    </evidence>
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        </source>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
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            <dbReference type="HAMAP-Rule" id="MF_00022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF19269"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP43907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="488" mass="54519" checksum="A41D5130215F0F1C" modified="2017-04-12" version="1">MTDLVPARTRVAPSPTGDPHVGTAFMALFDVAWARKTGGSFVLRIEDTDQARLVAGSEQQIYDSLEWLGLQPDEGPHVGGEHGPYRQSERLDTYRPFVDRLIADGHAYYCWCSPGRLAELRKEQEAAKLSVTGYDRLCLGKSREERSELPGFSETPVVRMLIPDDVELEFDDIVRGRVKAPRPDDQVILKADGFPTYHLAVVVDDHLMGINTVVRGEEWISSTPKHVLLYRWLGWDLPSFAHMPLLRNTDKSKISKRKNPAARLMWFKEQGYLPEAVRNFLQLLGYAGDDSGEVKSFDDFVAEFAWEKVNTVGPIFDLKKLDWLNGHYIRELSTEELADRIATFAEESGQWSDPSERELEVLRLAVPIIQERLVLLKDALPQLDYLFAADDEVTLDGDAVAGLTDDAPAVLDAAMEVAGSVDFTAEAIQAGLRERIVEAMGIKPKFAFAPLRVAISGRKVSPPLFESMEILGRESSLARLQALRAQLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCU0</accession>
    <name>A0A1Q2CCU0_9ACTN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">RPIT_03090</name>
        <name evidence="3" type="ORF">SAMN05428934_101219</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY28844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43924">
        <property type="protein sequence ID" value="AQP43924"/>
        <property type="gene ID" value="RPIT_03090"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY28844">
        <property type="protein sequence ID" value="SDY28844"/>
        <property type="gene ID" value="SAMN05428934_101219"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03090"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="DUF6498"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY28844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="207" mass="21958" checksum="8160B7A4023A3C8D" modified="2017-04-12" version="1">MRTQSLRLVLLAILNSIVQFLGVMLWRWPIGNVFLLFWVENVIITIMSIARVAAVPRGDGGELAGKLIASSVLAIFAVVHGAFTVALALATGLNLGAAFFAVPVVVLILRYAVEALGWFGPRAPRPSSIDDGYRFALRRIVTLHIAIMASWFVLVFGIIRLVQDGGAAAPLGASLPLVALAILLLAKTVSEISSLRGQAAVQPAPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCV5</accession>
    <name>A0A1Q2CCV5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (Decyclizing)</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_03235</name>
        <name evidence="8" type="ORF">SAMN05428934_101248</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03235"/>
    <dbReference type="EnsemblBacteria" id="AQP43948">
        <property type="protein sequence ID" value="AQP43948"/>
        <property type="gene ID" value="RPIT_03235"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29760">
        <property type="protein sequence ID" value="SDY29760"/>
        <property type="gene ID" value="SAMN05428934_101248"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03235"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016823">
        <property type="term" value="F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019310">
        <property type="term" value="P:inositol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030817">
        <property type="entry name" value="Myo_inos_IolD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968:SF9">
        <property type="entry name" value="PTHR18968:SF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04377">
        <property type="entry name" value="myo_inos_iolD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="6">
        <location>
            <begin position="8"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="4">
        <location>
            <begin position="227"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="5">
        <location>
            <begin position="424"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="609"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="613"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY29760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="630" mass="68475" checksum="CF420C6DA9CC6767" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCX5</accession>
    <name>A0A1Q2CCX5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsK</name>
        <name evidence="9" type="ORF">RPIT_03360</name>
        <name evidence="10" type="ORF">SAMN05428934_101272</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03360"/>
    <dbReference type="EnsemblBacteria" id="AQP43972">
        <property type="protein sequence ID" value="AQP43972"/>
        <property type="gene ID" value="RPIT_03360"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30498">
        <property type="protein sequence ID" value="SDY30498"/>
        <property type="gene ID" value="SAMN05428934_101272"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03360"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019981">
        <property type="entry name" value="Ribosomal_S11_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_S11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_S11_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="PTHR11759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03632">
        <property type="entry name" value="uS11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP43972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY30498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="135" mass="14176" checksum="883E91C004AB9555" modified="2017-04-12" version="1">MATASRKAAAKTKVRRKEKKNVLAGQAHIKSTFNNTIISITDPNGAVIAWASAGTVGFKGSRKSTPFAAQMAAEAAGRRAMEHGMKKVDVFVKGPGSGRETAIRSLGAVGLEVGAISDVTPVPHNGCRPPKRRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCY4</accession>
    <name>A0A1Q2CCY4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">16S rRNA m(2)G 1207 methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03420</name>
        <name evidence="3" type="ORF">SAMN05428934_101284</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03420"/>
    <dbReference type="EnsemblBacteria" id="AQP43982">
        <property type="protein sequence ID" value="AQP43982"/>
        <property type="gene ID" value="RPIT_03420"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30871">
        <property type="protein sequence ID" value="SDY30871"/>
        <property type="gene ID" value="SAMN05428934_101284"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03420"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTS" evidence="1">
        <location>
            <begin position="25"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY30871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="198" mass="21334" checksum="519060E12130E182" modified="2017-04-12" version="1">MTHYFHTPQDPLVTHEFSATIFGRELTFTAARGVFSGGRLDLGTSVLLREVEPPTSGHVLDLGCGVGTIAIGLAVASPALTVDAVDVNDRALELTGLNARRHGVADRVRALRPSEVDPAVAYDEIWSNPPIRIGKQALHELLLMWLTRLTLDGAAYLVVGKNLGGDSLQRWLDDQGFPTGRVASAKGFRVLRVTPSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD17</accession>
    <name>A0A1Q2CD17_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transglutaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03485"/>
    <dbReference type="EnsemblBacteria" id="AQP43991">
        <property type="protein sequence ID" value="AQP43991"/>
        <property type="gene ID" value="RPIT_03485"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03485"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TGc" evidence="1">
        <location>
            <begin position="151"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="267" mass="29132" checksum="1ECE7AFA2083F1BA" modified="2017-04-12" version="1">MTSRHVSSTLIVDVRQPADLVFSVAVSSEYPEVRETLSFRVGDEDVAVEEVVAPSGSRLHRLRETPVGSLTVDYTAAVHGRSPEPPLLGIDEILYTRPSRYCDSDRLANLAHAHFEGLTGRELVRAVTDWVSTNIAYRPGSSRVVDGALETYLDRAGVCRDYAHLVVALLRGRNVPARMASVYAPGLKPMDFHAVAEVFLEGRWHVIDATGLAPRQSMVRICTGRDAADTAFMTTLGGRTVLTSMTVNAWVDGDLPVDDRSEPATLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD40</accession>
    <name>A0A1Q2CD40_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome bc1 complex cytochrome b subunit</fullName>
            <ecNumber evidence="2">7.1.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Cytochrome bc1 reductase complex subunit QcrB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_03705</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:11484"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="7.1.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="7.1.1.8" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03705"/>
    <dbReference type="EnsemblBacteria" id="AQP44029">
        <property type="protein sequence ID" value="AQP44029"/>
        <property type="gene ID" value="RPIT_03705"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03705"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008121">
        <property type="term" value="F:ubiquinol-cytochrome-c reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005797">
        <property type="entry name" value="Cyt_b/b6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027387">
        <property type="entry name" value="Cytb/b6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13631">
        <property type="entry name" value="Cytochrom_B_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51002">
        <property type="entry name" value="CYTB_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="269"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="343"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="393"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="CYTB_NTER" evidence="9">
        <location>
            <begin position="29"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="565" mass="61922" checksum="97FA52A154DA6E8B" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD51</accession>
    <name>A0A1Q2CD51_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_03835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03835"/>
    <dbReference type="EnsemblBacteria" id="AQP44052">
        <property type="protein sequence ID" value="AQP44052"/>
        <property type="gene ID" value="RPIT_03835"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03835"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="580" mass="63071" checksum="C026726E47778564" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD70</accession>
    <name>A0A1Q2CD70_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_03945</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44072">
        <property type="protein sequence ID" value="AQP44072"/>
        <property type="gene ID" value="RPIT_03945"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03945"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="88" mass="9536" checksum="5098E810B26092B4" modified="2017-04-12" version="1">MIDLILTRARVLAYEADLIDSPAERYLTAYRAAEQVALSVVSGLPGPSSRQTVWPLLARVAPSSQSGRVSFSRSAPGRSLCRPVLPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDA9</accession>
    <name>A0A1Q2CDA9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dephospho-CoA kinase</fullName>
            <ecNumber evidence="1">2.7.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Dephosphocoenzyme A kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">coaE</name>
        <name evidence="2" type="ORF">RPIT_04125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3'-dephospho-CoA + ATP = ADP + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18245"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 5/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CoaE family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.24" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04125"/>
    <dbReference type="EnsemblBacteria" id="AQP44099">
        <property type="protein sequence ID" value="AQP44099"/>
        <property type="gene ID" value="RPIT_04125"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04125"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00356"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004140">
        <property type="term" value="F:dephospho-CoA kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00376">
        <property type="entry name" value="Dephospho_CoA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001977">
        <property type="entry name" value="Depp_CoAkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01121">
        <property type="entry name" value="CoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00152">
        <property type="entry name" value="TIGR00152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51219">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="11"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="197" mass="21537" checksum="CE148B2842792A7E" modified="2017-04-12" version="1">MARIALTGGIASGKSMVSDDLARRGAVIIDSDVLAREVVEPGTEGLHRIVERFGSEVLNADGSLDRAKLGNLIFSDERSREDLNAIVHPLVRARARELESAAPPDALVVHVIPLLVETGLDREFDRVIVVDAPAETQARRLMRRNNLGNQDAMARINAQASRRQRLSVADWVVDNSSDQASTVQQIDRIWADLTAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDE2</accession>
    <name>A0A1Q2CDE2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glucose-6-phosphate dehydrogenase assembly protein OpcA</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">OpcA protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04265</name>
        <name evidence="3" type="ORF">SAMN05428934_101457</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY35824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04265"/>
    <dbReference type="EnsemblBacteria" id="AQP44124">
        <property type="protein sequence ID" value="AQP44124"/>
        <property type="gene ID" value="RPIT_04265"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY35824">
        <property type="protein sequence ID" value="SDY35824"/>
        <property type="gene ID" value="SAMN05428934_101457"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04265"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004555">
        <property type="entry name" value="G6PDH_assembly_OpcA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38658">
        <property type="entry name" value="PTHR38658"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10128">
        <property type="entry name" value="OpcA_G6PD_assem"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY35824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="301" mass="32636" checksum="98FBDC79F823043D" modified="2017-04-12" version="1">MILDLSDTSSREIASALIKARRTVGSASGLVLTLLIVTNDFHFDEVLEAAKASATAHPSRVIVVTYVDAEEPRLDAKIEVGEGLPGDLVVLRLHGELQHHGDAICLPLLLPDSPTIVWWPNHAPDNLADDPIGSLADRRITDAAGESDPREALTRRAGNHAPGDTDLTWTRLTRWRALLAAALDQSQATVTGGMVRSAPDNAPATLLAAWLEDRLGVEIRRVDGEQPGVNEVILDTPDGPITINRIHDGTALYQVPGQPQRTVALRRRPLTDLLTEELQRMDADDIFEAATRRVAAEAEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDK5</accession>
    <name>A0A1Q2CDK5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutamate 5-kinase</fullName>
            <ecNumber evidence="8">2.7.2.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Gamma-glutamyl kinase</fullName>
            <shortName evidence="8">GK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">proB</name>
        <name evidence="11" type="ORF">RPIT_04680</name>
        <name evidence="12" type="ORF">SAMN05428934_101543</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + L-glutamate = ADP + L-glutamyl 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14877"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the glutamate 5-kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.11" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04680"/>
    <dbReference type="EnsemblBacteria" id="AQP44198">
        <property type="protein sequence ID" value="AQP44198"/>
        <property type="gene ID" value="RPIT_04680"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37922">
        <property type="protein sequence ID" value="SDY37922"/>
        <property type="gene ID" value="SAMN05428934_101543"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04680"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00359"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004349">
        <property type="term" value="F:glutamate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04242">
        <property type="entry name" value="AAK_G5K_ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00456">
        <property type="entry name" value="ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041739">
        <property type="entry name" value="G5K_ProB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011529">
        <property type="entry name" value="Glu_5kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005715">
        <property type="entry name" value="Glu_5kinase/COase_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019797">
        <property type="entry name" value="Glutamate_5-kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000729">
        <property type="entry name" value="GK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01027">
        <property type="entry name" value="proB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00902">
        <property type="entry name" value="GLUTAMATE_5_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 8" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA" evidence="10">
        <location>
            <begin position="276"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="173"/>
            <end position="174"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="213"/>
            <end position="219"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY37922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="365" mass="39181" checksum="94CD5C69545B47A4" modified="2017-04-12" version="1">MRSEIADAKRVVVKVGSSSLTGPDGHLDHGRVRELARLLSALHGRGARVVLVTSGAIAAGLLPLGLTRRPRDLETQQAAAAVGQGLLVRHYADAFAEHGVTVAQLLLTVEDVLRPRTYRNALNTISRLFRLGVVPIVNENDTVATHEIRFGDNDKLAALIAHLVRADALLLMSDVDGLYTAHPDTPGARRIDRVDDLTTLDVDTSRVGSKVGTGGMRTKLQAADIATQAGVSVVLGHADDLERALAGDEVGTFFAPVRKRRPRRLLWLAFAAEPRGFLHVDAGARDALLHGKASLLAAGIREVRGVFSEGEPVEMIGPDGHPVGRGFVAYSSADLEHEMGHSSSEAGHRHQRPVVHRDHMMLATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDK9</accession>
    <name>A0A1Q2CDK9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome maturation factor RimP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rimP</name>
        <name evidence="6" type="ORF">RPIT_04570</name>
        <name evidence="7" type="ORF">SAMN05428934_101520</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for maturation of 30S ribosomal subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RimP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04570"/>
    <dbReference type="EnsemblBacteria" id="AQP44177">
        <property type="protein sequence ID" value="AQP44177"/>
        <property type="gene ID" value="RPIT_04570"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37388">
        <property type="protein sequence ID" value="SDY37388"/>
        <property type="gene ID" value="SAMN05428934_101520"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04570"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01734">
        <property type="entry name" value="YlxS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01077">
        <property type="entry name" value="RimP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003728">
        <property type="entry name" value="Ribosome_maturation_RimP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028998">
        <property type="entry name" value="RimP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036847">
        <property type="entry name" value="RimP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028989">
        <property type="entry name" value="RimP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035956">
        <property type="entry name" value="RimP_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33867">
        <property type="entry name" value="PTHR33867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02576">
        <property type="entry name" value="DUF150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17384">
        <property type="entry name" value="DUF150_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74942">
        <property type="entry name" value="SSF74942"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75420">
        <property type="entry name" value="SSF75420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="DUF150" evidence="4">
        <location>
            <begin position="10"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="DUF150_C" evidence="5">
        <location>
            <begin position="89"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY37388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="161" mass="17066" checksum="0440AD7EA97AC3BC" modified="2017-04-12" version="1">MQDSQLASVIEPILASHGLELDSLDVTPVGKRSILRITVDGDGPSGRGPLLDDIASASSAISAALDESTAVGNSPYTLEVSSRGVSKPLTEAKHYRRNTGRLVKLNLADETLTGRIQEVADDTVTIEIDGTQRVIALADITKAVVQVELNRPADDFDGEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE55</accession>
    <name>A0A1Q2CE55_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PTS EIIA type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_05945</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05945"/>
    <dbReference type="EnsemblBacteria" id="AQP44412">
        <property type="protein sequence ID" value="AQP44412"/>
        <property type="gene ID" value="RPIT_05945"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05945"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001127">
        <property type="entry name" value="PTS_EIIA_1_perm"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00358">
        <property type="entry name" value="PTS_EIIA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51093">
        <property type="entry name" value="PTS_EIIA_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PTS EIIA type-1" evidence="3">
        <location>
            <begin position="21"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="150" mass="15853" checksum="F19445C5C646A9B0" modified="2017-04-12" version="1">MMLEVLAPCPGHVIAMSEVDDPVFSVGAVGPGVGIEPRPGQTAVVSPVDGVLIKLSPHAFIVLVDDEIGVLVHIGINTVRLDGEGFELLAAEGDRVEAGTPVVSWDPGSITDPDMRDTVIVAVMDQEPDSLRIDEVNHDVDAGRVLFRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE86</accession>
    <name>A0A1Q2CE86_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05685</name>
        <name evidence="3" type="ORF">SAMN05428934_10384</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44365">
        <property type="protein sequence ID" value="AQP44365"/>
        <property type="gene ID" value="RPIT_05685"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67233">
        <property type="protein sequence ID" value="SDY67233"/>
        <property type="gene ID" value="SAMN05428934_10384"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05685"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045057">
        <property type="entry name" value="Gcn5-rel_NAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031165">
        <property type="entry name" value="GNAT_YJDJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31435">
        <property type="entry name" value="PTHR31435"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14542">
        <property type="entry name" value="Acetyltransf_CG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51729">
        <property type="entry name" value="GNAT_YJDJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY67233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="94" mass="10701" checksum="D95671540E5159C3" modified="2017-04-12" version="1">MTHHVSLTTNESENRFELHHGDELIGRIDYEMSGDAIDLTHTEVDPDHGGQGYAQRLVEYALTHARERDLSVKASCPYVAKYLDQHDEHADLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEA6</accession>
    <name>A0A1Q2CEA6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidohydro_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05795</name>
        <name evidence="3" type="ORF">SAMN05428934_103106</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05795"/>
    <dbReference type="EnsemblBacteria" id="AQP44385">
        <property type="protein sequence ID" value="AQP44385"/>
        <property type="gene ID" value="RPIT_05795"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67855">
        <property type="protein sequence ID" value="SDY67855"/>
        <property type="gene ID" value="SAMN05428934_103106"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05795"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro_3" evidence="1">
        <location>
            <begin position="44"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY67855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="476" mass="49378" checksum="0084B153676A5BE5" modified="2017-04-12" version="1">MKLTVTRARTPRDLYATGSDLIDVEVCDGVIAAIRPSGGQVAGRVLDADGATILPGLWDAHVHLAHHAMVASAIDVSGTDSAEATVAILEREAARRPGEILLGFGFRAGGWGDPPSASLLDAVTSQPIALISGDAHSFWANTAGLALAGFAGHPSGFLVEHEAFAAQVQLMDAAADHIDEAVRSVSLAAARRGVVGVVDMQMGWTIGAWRRRAATPPPLKVLAAIYPDDLDRAVTSGLRSGDRIAERVWVGPLKIIADGSLHSRTALCTDEYPDPLPHLPHGQANYDQSELERLLGVAAGHGLDVAVHAIGDLAVTRVLDAFAATGARGSVEHAQFVTPANISRFAHLGVAASAQPAHLLDDAGSLDDIWPGAGGQAFPLRSLLDAGATLRFGSDAPVAPLDPWLAMDAAVNRTHHPEQSITPGEAILASVRSSLAVGQPADLILVDAPTEALAEGRFGAVQVMATILDGAITFAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEA9</accession>
    <name>A0A1Q2CEA9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized conserved protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06065</name>
        <name evidence="3" type="ORF">SAMN05428934_103159</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY69193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06065"/>
    <dbReference type="EnsemblBacteria" id="AQP44431">
        <property type="protein sequence ID" value="AQP44431"/>
        <property type="gene ID" value="RPIT_06065"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY69193">
        <property type="protein sequence ID" value="SDY69193"/>
        <property type="gene ID" value="SAMN05428934_103159"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06065"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sacchrp_dh_NADP" evidence="1">
        <location>
            <begin position="4"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY69193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="354" mass="37341" checksum="DAF8C616975B2B91" modified="2017-04-12" version="1">MKWLIFGAYGYSGALIAREAKARGLTPVLAGRNPDRLRPLADELGLDWRAFALDRPDDLDGGLEGIGLVLHCAGPFSRTSAPMIEACLRNGAHYLDITGEIDVFEHAHAQANRARLADVVLCPGVGFDVIPTDCVARVLADELPDATHLLLGFDAASGLSPGTAKTAAESAGYGGRIRRDGRLVAVPLGHAPRRIDFGRGATTAMTIPWGDVATAYYSTGIPNIAVYVPASRRAIAAAKIADYLRPLLRTGAVRAMLTGLAERYVTGPDLAARERGSTYVWGEARNSLGEVRTARVKTASGYAVTVTGSLAVVQHLLETSVAGGSYTPSLLLGPRFLETLPGTDGPIVVSDQSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEC1</accession>
    <name>A0A1Q2CEC1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Homoserine O-succinyltransferase</fullName>
            <shortName evidence="2">HST</shortName>
            <ecNumber evidence="2">2.3.1.46</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Homoserine transsuccinylase</fullName>
            <shortName evidence="2">HTS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">metXS</name>
        <name evidence="5" type="ORF">RPIT_06005</name>
        <name evidence="6" type="ORF">SAMN05428934_103147</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-homoserine + succinyl-CoA = CoA + O-succinyl-L-homoserine</text>
            <dbReference type="Rhea" id="RHEA:22008"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57661"/>
            <dbReference type="EC" id="2.3.1.46"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; O-succinyl-L-homoserine from L-homoserine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.46" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06005"/>
    <dbReference type="EnsemblBacteria" id="AQP44420">
        <property type="protein sequence ID" value="AQP44420"/>
        <property type="gene ID" value="RPIT_06005"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68900">
        <property type="protein sequence ID" value="SDY68900"/>
        <property type="gene ID" value="SAMN05428934_103147"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06005"/>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008899">
        <property type="term" value="F:homoserine O-succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00296">
        <property type="entry name" value="MetX_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="PTHR32268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01392">
        <property type="entry name" value="homoserO_Ac_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="53"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2 3">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="354"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="355"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for acyl-CoA specificity" evidence="2">
        <location>
            <position position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000443-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY68900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="380" mass="41958" checksum="FF3665305923142B" modified="2017-04-12" version="1">MKAAASPSLGVVETHSATVFDAARPLHLRSGATLDHVEVAYETYGTLNEQRSNAVYICHALTGDAHAAGYHDGDDKPGWWDNMIGPGKPIDTDRWFVVCANILGGCQGTTGPASINPATGEPYALDFPLLHVADFVEVHRALARHLGIARFAAVVGGSLGGMQVLQWAMLYPSELGRALIFAASSRLTAQNIAFSAVGRQAIMRDSGFSEGKFLSRGTAPRKGLAVARMMAHITYLSEEAFQEKFGRQSQRDELKPNFGVDFAVESYLEYQGQRFLSRFDALSYLYLTRVMDYFDPFADEGALDALIAEPVRFLVVSFDSDWRFSTEHSRRIVRHLEGAGLPTSFREIRSSWGHDSFLLELPDYHATVRAYLDRAAEELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEW1</accession>
    <name>A0A1Q2CEW1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peripla_BP_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07345"/>
    <dbReference type="EnsemblBacteria" id="AQP44646">
        <property type="protein sequence ID" value="AQP44646"/>
        <property type="gene ID" value="RPIT_07345"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07345"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peripla_BP_3" evidence="1">
        <location>
            <begin position="31"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="148" mass="15509" checksum="DBC8DF2EAE5B1F5A" modified="2017-04-12" version="1">MNHASETCVKPRWKAADIATFARIVRSTLNAITTALAAAIAEGLAFDAVFAVTDAGAIGAFRALGEAGRVMPDDVQVVGFDNLALAPYLVPSLTTIEPDNDAMVDAVCELVLTSLGLDAPAATGDRGRVRMPTARIVRRESTRGPTRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEY4</accession>
    <name>A0A1Q2CEY4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Isochorismatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07405"/>
    <dbReference type="EnsemblBacteria" id="AQP44657">
        <property type="protein sequence ID" value="AQP44657"/>
        <property type="gene ID" value="RPIT_07405"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07405"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="17"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="112" mass="11874" checksum="5AE42BB488E47249" modified="2017-04-12" version="1">MSWSLHSEIERRMDPTWKRVSKDKGSVVAGTDVARWLAERDVDTITIVGYMTNNCDIATAVGADELGLAAEILSDAPVATTQAWATAVTARHALPKSDLGTSATQGRAAFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF39</accession>
    <name>A0A1Q2CF39_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07800"/>
    <dbReference type="EnsemblBacteria" id="AQP44721">
        <property type="protein sequence ID" value="AQP44721"/>
        <property type="gene ID" value="RPIT_07800"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07800"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="216" mass="24534" checksum="C656B99303F36B72" modified="2017-04-12" version="1">MILSELIRRGRGERILVVTPRHVLEQMQHEMWSRFAIPFVRLDSQGVARVKQKLPANRNPFSYFRRVIISIDTLKQERFVHDLRRHHWDAVVIDESHNVTNTATLNNRLASILAPQADALILASATPHNGSRESFAELVRLLDPTAVKADGDLDAKRVDQLTIRRHRHSAEVAEEVGADWAERLEPDNRLIDASPQEDAVVDELVDTWLGPTLVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF96</accession>
    <name>A0A1Q2CF96_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cysteine-rich secretory protein family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_08085</name>
        <name evidence="4" type="ORF">SAMN05428934_11357</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ17090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08085"/>
    <dbReference type="EnsemblBacteria" id="AQP44767">
        <property type="protein sequence ID" value="AQP44767"/>
        <property type="gene ID" value="RPIT_08085"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ17090">
        <property type="protein sequence ID" value="SDZ17090"/>
        <property type="gene ID" value="SAMN05428934_11357"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08085"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="SSF55797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544466" evidence="1">
        <location>
            <begin position="29"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="2">
        <location>
            <begin position="78"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ17090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="449" mass="49114" checksum="99E4F887DCB4B5AD" modified="2017-04-12" version="1">MKSRSLSLLAAGTLAVSTLIATPSIAHADIAVDRQDAASVRAATQEVSRMTALPANWTGSTRTCAPGTTSSAHRAATLSTINLMRSFVGQEPVVEDPQWSAKAAQAALMMAAADRLSHYPDSTWPCYTPDGAEAAARSNLAYFNDGMGGGRTGASSILQYMDDQGAQNRAVGHRMWLLDPRATQMGWADTTTTNATWVVGEFTGSSPRTGDRWVTWPSEGFFPHQLLPTSRRWSFSSRETIDELSAATISVRGPDGPIAVTEVFRTSELLVWEMPTLPVPTGSGSAVYTVTISGIRRIVGEPPVSHSYQVKVIDGMWVDVYTTPGTHHVGGRDWRTTCSKYSSTVERCRAEIRATVVTYANGRFTSTTGWAFNNLSYKPSSRAQWATNPLAIRGEHIIDGRRWRTRCDDEWTGRGACRSEIWATVPVLEDGRWTLGQKFVFNNVVYFSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFB1</accession>
    <name>A0A1Q2CFB1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA methyltransferase, TrmH family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">rRNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08265</name>
        <name evidence="3" type="ORF">SAMN05428934_11522</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08265"/>
    <dbReference type="EnsemblBacteria" id="AQP44793">
        <property type="protein sequence ID" value="AQP44793"/>
        <property type="gene ID" value="RPIT_08265"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19448">
        <property type="protein sequence ID" value="SDZ19448"/>
        <property type="gene ID" value="SAMN05428934_11522"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08265"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08032">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_sub_bind" evidence="1">
        <location>
            <begin position="35"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ19448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="271" mass="28577" checksum="9D4A003CCE7C9FD2" modified="2017-04-12" version="1">MTTEPNAAPGLPASVLRSVRRLTQRRGRDLTGMFLAEGRQAVREALGSPGRVQEIIVDDAVRHADLLDGLELPVWQADEHQMRQLSDTVTPQGVVAVCRQLDFDWESLDGARLVVICAQVRDPGNAGTVIRCADAFGADAVILTSGSVEIYNPKTVRSTVGSIFHLPILTGVTLAEAVERVKGLGMTVLAADGEGDPLDLKAASGGLSGPIAWIMGNEAWGLPADDARLADEVVAVPMWGQAESLNLSSAAAVCLYATASAQRRETGKGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFB6</accession>
    <name>A0A1Q2CFB6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LD-carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_08235</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S66 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08235"/>
    <dbReference type="EnsemblBacteria" id="AQP44787">
        <property type="protein sequence ID" value="AQP44787"/>
        <property type="gene ID" value="RPIT_08235"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08235"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027461">
        <property type="entry name" value="Carboxypeptidase_A_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027478">
        <property type="entry name" value="LdcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040449">
        <property type="entry name" value="Peptidase_S66_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040921">
        <property type="entry name" value="Peptidase_S66C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003507">
        <property type="entry name" value="S66_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30237">
        <property type="entry name" value="PTHR30237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02016">
        <property type="entry name" value="Peptidase_S66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17676">
        <property type="entry name" value="Peptidase_S66C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141986">
        <property type="entry name" value="SSF141986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S66" evidence="3">
        <location>
            <begin position="19"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S66C" evidence="4">
        <location>
            <begin position="208"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="351" mass="37895" checksum="3E1CEB38219620D1" modified="2017-04-12" version="1">MASPHRPAAPPKARPGDRIAVLSTSFAAPAAYPAVHEQALRRLREVTGLEPVEFPTTRAHNPSPEARAADINAAFADPSIRAIQAVVGGDDLITVVPHLDADAALNDPKPFLGYSDNTHLHNWLWHLGIASYYGGSTQVHLGPGPDVDEIHARSLLAALMKGGAIELTRPGRSEDFGHDWADPRALTAEGDRRPTEPWVWLGPRRAVSGRTWGGCLEVVVDILAAGRFELGPSALAGGILLVETSEELPSATRVHRYLRALGERGLLSHVAGVMVAQPPVSSFDDQPDDETRTRRRAEQADAVERVVSRYCPHAVVVIGVPFGHTRPQWIVPYGGRITVDGMGRQVTADYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFC2</accession>
    <name>A0A1Q2CFC2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08410</name>
        <name evidence="3" type="ORF">SAMN05428934_1206</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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    <sequence length="196" mass="21618" checksum="71342B5F3255D592" modified="2017-04-12" version="1">MKSVDRLAERLAHGVQGWMAMAAVVLFAVFTAMVLPVQAEAGAFYTVRYPAPDTSLWYSADDLYSAAEAWGRDGRAAYVHARVTFDVVWPLVYGTFLVTTLAWVCARATAEGSRWRRLALLPVVVVALDYAENVCAATVMARYPARTPPLADLAPIFTAGKWLALSASFLLLLIGVIIALAARWRSARLHPRRREH</sequence>
</entry>
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
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            </authorList>
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        </source>
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    </dbReference>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="SDZ19074.1"/>
        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="135" mass="13902" checksum="D6F91D7B7B17FCCD" modified="2017-04-12" version="1">MEVLGLADGAALVITGMASPPTADEPPGQGTLSLPAEVATWIGEAVAAGVTFEVLKEASVALVRQGWTKKGTTATAESVTQAVVQYLRSCGYIEIVVSEVRRVSGQGWTLTGTADGSRFGGMADDGGNLVHVRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFJ6</accession>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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    </evidence>
    <evidence type="ECO:0000313" key="3">
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            <dbReference type="Proteomes" id="UP000188324"/>
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    </evidence>
    <sequence length="435" mass="47629" checksum="DB1DD64CC499A685" modified="2017-04-12" version="1">MPRVRNPMIRTLIDLRGNGRASVYTEPLWGLSMMLVLPYASVFMLELGVRDEQIGLLATISILSQVIFGLLSGVITDKLGRRMTTAAFDIIAWVIPCVVWALAQNFWWFLAASVINGAWQVTQNSWDCLLVEDVDRAEIPRVYALVKAAGEFSALFAPIAAFLVSGFGLEIAVRILYANAALIMTLKIWLLFRYSTETATGRVRMAQTKGVSIWRSLSEYRGVLGLIVRSKGTLFSLSIAAIVGAVALVNATFWQLAINQRLSVPDALLPFFPMVRSLLSLLFYFTLIPLLTHSKQLRTPTLIGFAVYLAGQALLVATPVPDGEAQLSTYALLGGCLVLDAFGGAMLFMLAESLVALHVDRDERSRVMAIQRTCVMLVTAPFGWISGWLSGMDRSWPFLLTSGLLILGILVAGLMWVTTHDDAPTATTPTVPTNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFP4</accession>
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                <person name="Schumann P."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">RP1T</strain>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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    </dbReference>
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        <property type="protein sequence ID" value="SDY97466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08740"/>
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        <property type="protein sequence ID" value="AQP44865"/>
        <property type="gene ID" value="RPIT_08740"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY97466"/>
        <property type="gene ID" value="SAMN05428934_10758"/>
    </dbReference>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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            <end position="64"/>
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        <location>
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        </location>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="292"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="365"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY97466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="394" mass="40891" checksum="DC712D84D90C22E6" modified="2017-04-12" version="1">MLVALRRWWPLVALLTLAFNLRPVAVSVGPVLQEISRDIGLSGTSAGLLTSLPTLCFAAFGALAPGFARRVGAHTAIALSLAALVLGQAARLLTSSSVAFLGLSVLALGGMAVANVLLPSLVREHYPHRVGLATALYSLTMTIGVTLASSVTVPLAHALGGWRASLTAGVIAAAVALACWLPLARHRPAPHHGDIRHVSLRMIARTKLGWALAIMFGCQSAQAYTIFGWLPSVYRSAGMDEVNAGLMLGIATGVGIIPSFLIPAYVARTRNPSILFLSIVACLAAGYLGLMLDPLGFPALWALLLALGTASFPLLLALFGTRARTPTATAALSGFAQSVGYSLASLGPLSFGLLHTVTGGWTVPISVQLSLTVPMVIAGLYACRPQVVEDQLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFT1</accession>
    <name>A0A1Q2CFT1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MTH538 TIR-like domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09455</name>
        <name evidence="3" type="ORF">SAMN05428934_102415</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY60129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44982">
        <property type="protein sequence ID" value="AQP44982"/>
        <property type="gene ID" value="RPIT_09455"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY60129">
        <property type="protein sequence ID" value="SDY60129"/>
        <property type="gene ID" value="SAMN05428934_102415"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09455"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.9200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036490">
        <property type="entry name" value="MTH538_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015032">
        <property type="entry name" value="MTH538_TIR-like_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08937">
        <property type="entry name" value="DUF1863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52206">
        <property type="entry name" value="SSF52206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1863" evidence="1">
        <location>
            <begin position="3"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY60129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="161" mass="18314" checksum="2181F6C9220A60E7" modified="2017-04-12" version="1">MAKSVFYSFHYDRDKFRVNLVREIKSIAGGSEVTGQNWEEVRYKTDTAIQNWIDKEMNYKKAVIVLVGRQTAERPYVQYEIERAWSMKKPLLGVRIHGLASMRDGADSAGANPFEVAGLSGVPLFDPTATDWSGRIDTKATYNELARRLPVWAEQGVTKWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFX3</accession>
    <name>A0A1Q2CFX3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">IS5 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44945">
        <property type="protein sequence ID" value="AQP44945"/>
        <property type="gene ID" value="RPIT_09230"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09230"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="2">
        <location>
            <begin position="10"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="175" mass="19541" checksum="BE5D36348F29280F" modified="2017-04-12" version="1">MMQMPEPVDHAIGRSRGGLSTKVHQLCDGKGRPMVIAVGPGQGSDSKMFPHLLAAVRVPRDGVGRPRTTPDAVLADKAYSSRVHRTLLRSRGITAVIAEPRDQQSNRKRRGSRGGRPPLTDPGRYVKRHVIENSFERFKQWRGLATRYDKLASTYRAAVLMRAILLWLPALTERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFX7</accession>
    <name>A0A1Q2CFX7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09620"/>
    <dbReference type="EnsemblBacteria" id="AQP45014">
        <property type="protein sequence ID" value="AQP45014"/>
        <property type="gene ID" value="RPIT_09620"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09620"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="327" mass="35163" checksum="3F0BA1E399C84B82" modified="2017-04-12" version="1">MNPGVSVVMPVRNEERHLRAAVRRVLDQGYPGELEILVAVAPSDDRTRDIADELAAADRRVVVLDNPSGYTPAGLNIAVAASCHDIVVRVDGHGELSEDYIATAVRLLERTGAANVGGLMDAQGTSPLSEAIAAAYNSKLGLGGGGFHLADTPAGPADTVFLGVFRKAVLMEIGGFDESLHRAQDWELNYRLRQAGHLVYFSPDLRVVYRPRDSFRALAKQFFTTGQWRREVVSRHPDTLSLRYLAPPLTVLGIGTGVTGGVLGLLLRSRLLTSLFVAPLVYLAFLGAATTVIPGLRAAARLRLPFVLAVMHVAWGAGFIRGLPRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFY3</accession>
    <name>A0A1Q2CFY3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 9">Purine nucleoside phosphorylase</fullName>
            <ecNumber evidence="6 9">2.4.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Inosine-guanosine phosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_09705</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + a purine nucleobase</text>
            <dbReference type="Rhea" id="RHEA:36431"/>
            <dbReference type="ChEBI" id="CHEBI:26386"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57259"/>
            <dbReference type="ChEBI" id="CHEBI:142361"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Purine metabolism; purine nucleoside salvage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the PNP/MTAP phosphorylase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.1" evidence="6 9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09705"/>
    <dbReference type="EnsemblBacteria" id="AQP45026">
        <property type="protein sequence ID" value="AQP45026"/>
        <property type="gene ID" value="RPIT_09705"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09705"/>
    <dbReference type="UniPathway" id="UPA00606"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004731">
        <property type="term" value="F:purine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09009">
        <property type="entry name" value="PNP-EcPNPII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011269">
        <property type="entry name" value="PUNP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011268">
        <property type="entry name" value="Purine_phosphorylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11904">
        <property type="entry name" value="PTHR11904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000477">
        <property type="entry name" value="PurNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01697">
        <property type="entry name" value="PNPH-PUNA-XAPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01698">
        <property type="entry name" value="PUNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="11">
        <location>
            <begin position="26"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate binding" evidence="10">
        <location>
            <begin position="85"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>a purine D-ribonucleoside</name>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>a purine D-ribonucleoside</name>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000477-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP45026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="265" mass="27652" checksum="F9D039CE879765ED" modified="2017-04-12" version="1">MHDPFELAAEAADFLRRHFDVDRIDLALVLGSGWSSGADQLGESLGEIELGAVPGFSKPVVSGHGGALKLVRTQGGKVAAIFTGRTHYYEGRGVEPVVHGVRTAAKWGAETLVLTNGCGGLNPAWAPGTVVLIGDHINLTSDTPLRGATFIDMSEAYSKRLRELAHTVDPDLPEGVYVQFRGPQYETPAEVRMAGILGGDLVGMSTTLETIAAREAGLEVLGLSLVTNAAAGLSEENLNHAEVLQAGKDAGPRLAGLLAGIVGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG17</accession>
    <name>A0A1Q2CG17_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09855</name>
        <name evidence="4" type="ORF">SAMN05428934_102335</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY57915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09855"/>
    <dbReference type="EnsemblBacteria" id="AQP45053">
        <property type="protein sequence ID" value="AQP45053"/>
        <property type="gene ID" value="RPIT_09855"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57915">
        <property type="protein sequence ID" value="SDY57915"/>
        <property type="gene ID" value="SAMN05428934_102335"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09855"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045931">
        <property type="entry name" value="DUF6350"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19877">
        <property type="entry name" value="DUF6350"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="280"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="406"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY57915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="451" mass="45051" checksum="6EE65DC8E5854CC7" modified="2017-04-12" version="1">MAIRSSRHRTVAVDIGASRPSEPRRWPWPWYVAALAGPLGVLAAGWVVLAALTTVGWLTSPEAELTDALRLAADLLILAHGAPVTIAGQAVSIAPLGLTAGLVFLALPAASWAARQAAGQAGHIDDTGDIWADAEAVALRVGATFAGVYAAAVVIVAASLGVGSWRVLVGGLVVGGIAGLWGASKSVGHDPTHTWPGWLRAVPRALGAALLVVLAGASAVFVTALWLGRERVTDIVVALDGGVPALALLTALHLAYLPNLLLASASWMLGAGITVGDQSLVTMALSDVGFLPAIPVFGAVPVDASPASFWWLVVGVAAGCVAALAVALARPRARFDETALVGGLSGVAAGLLLVVLCALGSGSLGSDRLAHLGARVGELAVFAPTLLGLAGMAAGLILGLVRRPPRAAGASEDAPPADDAPADGAPPADDAATSDDSAAADEATERTTLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG31</accession>
    <name>A0A1Q2CG31_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase_M23 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_09875</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09875"/>
    <dbReference type="EnsemblBacteria" id="AQP45057">
        <property type="protein sequence ID" value="AQP45057"/>
        <property type="gene ID" value="RPIT_09875"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09875"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="3">
        <location>
            <begin position="242"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="150"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="353" mass="36355" checksum="24D0150BA8303E20" modified="2017-04-12" version="1">MQVNQSPNARRAAVADEVVDIEASNSPQRGSRSLAASRRLVAATVAGALSATALFAFAFNSRSTDMDASSESLNAEIAVPAAAASAAELGFADRSQEVSRSAVRSNLTEAVADENAKERTAALGASAETAAAEEWKSSTAVRDQLMDEDMKLVAAQSEKLRKEAEEAARLLAEAKKAAEEAAAAKAAAAKASASGSGSSKSADVAVSAQDVENLTTKGGSMPVKENYRMGAGFGARGSWSRYHTGQDFPAPTGTPIYAAASGVVLSSSAGGWAGVNVVIQHNNGGSTLYAHMSRKNVSPGATVKAGQLIGYVGNTGRSFGSHLHFEYYEPGVTPGDVYNASNPMSFLRSLGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG87</accession>
    <name>A0A1Q2CG87_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_10255</name>
        <name evidence="4" type="ORF">SAMN05428934_102254</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10255"/>
    <dbReference type="EnsemblBacteria" id="AQP45126">
        <property type="protein sequence ID" value="AQP45126"/>
        <property type="gene ID" value="RPIT_10255"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55692">
        <property type="protein sequence ID" value="SDY55692"/>
        <property type="gene ID" value="SAMN05428934_102254"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10255"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019880">
        <property type="entry name" value="OxyQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03539">
        <property type="entry name" value="DapC_actino"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="29"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY55692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="366" mass="38823" checksum="AFE21AC1926F1C2C" modified="2017-04-12" version="1">MALGARLPDFPWDTLADAKTTAAAHPDGIVDLSVGTPVDPTPALAREALAEASDAHGYPTVWGTPRVRQAIIDYLTGRWRAVPLSHESVMPVVGTKELVGWLPTLLALGADHAVVFPECAYPTYEVGALTAGARPVPLDDPGALPADASLVWINSPANPTGQILSLDVLRAFVAAARERGAVLASDECYGEFAWEAEPYSVLDPRVNDGDLTNLLAVGSLSKRSNAAGYRAGFVAGDPVIVQQLVGARKHLGMMVPAPIQAAMAAMLGDQTHVEEQRDRYLARRAKLRPALEAAGFRIDHSEGSLYLWATRGENCRDSVAWLAERGILAAPGDFYGAAAAQHVRVALTATDERIDAAVARLSTVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGA0</accession>
    <name>A0A1Q2CGA0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Phosphinothricin acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10290</name>
        <name evidence="3" type="ORF">SAMN05428934_102247</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10290"/>
    <dbReference type="EnsemblBacteria" id="AQP45133">
        <property type="protein sequence ID" value="AQP45133"/>
        <property type="gene ID" value="RPIT_10290"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55500">
        <property type="protein sequence ID" value="SDY55500"/>
        <property type="gene ID" value="SAMN05428934_102247"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10290"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY55500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="169" mass="18637" checksum="DBBF5180F29DF3BE" modified="2017-04-12" version="1">MPTIRPARLHDLSAITEIYNEAGVGTTASWALEPVTLEDRRAWFMSLTRKDYPVLVLVDADSIVGFASYGPFRPLAGWAPTVEHSVYIREGYRSAGGGRMLLNALIDYARGRGVRTMVGVIDGANDHSVAFHERMGFTQVGRIEEAGLKFGQWHDAVFMARKIDDGPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGA5</accession>
    <name>A0A1Q2CGA5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-L-isoaspartate O-methyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">L-isoaspartyl protein carboxyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Protein L-isoaspartyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Protein-beta-aspartate methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_10370</name>
        <name evidence="7" type="ORF">SAMN05428934_102231</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10370"/>
    <dbReference type="EnsemblBacteria" id="AQP45148">
        <property type="protein sequence ID" value="AQP45148"/>
        <property type="gene ID" value="RPIT_10370"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55067">
        <property type="protein sequence ID" value="SDY55067"/>
        <property type="gene ID" value="SAMN05428934_102231"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10370"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PTHR11579"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00030757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY55067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="196" mass="21225" checksum="0B3784519DDDB2D1" modified="2017-04-12" version="1">MDVAEAFDRVPRQRFLPKNMRPYWRLDRPLALAHGQTNSQPSTVAAMLRLLDVREGHRVLDIGAGSGWTTALLAELVGAEGRVLGLERISALADGARAALGQDWPWAEIRVADPHELGAAREAPFDRILVSAMADELPEPLIAQLADDGVLVAPVAGVMTRVHRDGDTPAITEHGYYSFVPLITGPDDAGDTTDYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGC1</accession>
    <name>A0A1Q2CGC1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Iron ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Iron complex transport system ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_10485</name>
        <name evidence="6" type="ORF">SAMN05428934_102208</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY54387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10485"/>
    <dbReference type="EnsemblBacteria" id="AQP45169">
        <property type="protein sequence ID" value="AQP45169"/>
        <property type="gene ID" value="RPIT_10485"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY54387">
        <property type="protein sequence ID" value="SDY54387"/>
        <property type="gene ID" value="SAMN05428934_102208"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10485"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY54387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="291" mass="31662" checksum="2F839E675673C3C3" modified="2017-04-12" version="1">MIEVKEVTKAYGKSVVVDNVSLNLRSGGLTAIVGANGAGKSTLLSMIARLLPIDAGAIQVADYDVTTGDSRELARKLAILRQTNELQSRLTVADLVAFGRYPHSGGRLTAEDREKVDEAIGWMDLTALRDRFLDEMSGGQRQRAFVAMVLAQDTEYMLLDEPLNNLDVSHAHAMLRTLRRAADELGKTVVIVVHDINYASCWADQIVAMKDGRIRKVGSPREIVQRELLREVFDLDIEVAEFAGHPIAHFYLPVPVCSNCNGASCGTCCLDGARESSGPIPVSLSAGAQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGD5</accession>
    <name>A0A1Q2CGD5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_10220</name>
        <name evidence="4" type="ORF">SAMN05428934_102261</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10220"/>
    <dbReference type="EnsemblBacteria" id="AQP45120">
        <property type="protein sequence ID" value="AQP45120"/>
        <property type="gene ID" value="RPIT_10220"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55874">
        <property type="protein sequence ID" value="SDY55874"/>
        <property type="gene ID" value="SAMN05428934_102261"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10220"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544484" evidence="2">
        <location>
            <begin position="23"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY55874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="274" mass="29076" checksum="03F9042C0B03FB08" modified="2017-04-12" version="1">MRRSLVVALAAIVALAAVGVVAWQAYRAVVGSLTPQTCRVVLPDGGSTSLSGEQARNAAIIVAASIERGLPERAAVVALATAYQESDIRNLDYGDRDSLGLFQQRPSYGWGTEEQIMDPWYSSGRFYEELVKFPGWESVDVNDMAQRVQRSGFPDAYRQHESKATAVAAALRGSAPETLSCLARDENPPDPAAFSPVLEAWGDQVTTTVEGDVVTITASSDIALWSAAHLALANTYESGLTAAVVGDREWTASDHGWQPAATPAPPGTATLTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGE8</accession>
    <name>A0A1Q2CGE8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Exodeoxyribonuclease 7 small subunit</fullName>
            <ecNumber evidence="3">3.1.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Exodeoxyribonuclease VII small subunit</fullName>
            <shortName evidence="3">Exonuclease VII small subunit</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">xseB</name>
        <name evidence="5" type="ORF">RPIT_10525</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterooligomer composed of large and small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the XseB family.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.6" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10525"/>
    <dbReference type="EnsemblBacteria" id="AQP45177">
        <property type="protein sequence ID" value="AQP45177"/>
        <property type="gene ID" value="RPIT_10525"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10525"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00337">
        <property type="entry name" value="Exonuc_7_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003761">
        <property type="entry name" value="Exonuc_VII_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037004">
        <property type="entry name" value="Exonuc_VII_ssu_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34137">
        <property type="entry name" value="PTHR34137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02609">
        <property type="entry name" value="Exonuc_VII_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116842">
        <property type="entry name" value="SSF116842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01280">
        <property type="entry name" value="xseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="94" mass="10558" checksum="C6AD0290EF6DD80D" modified="2017-04-12" version="1">MASLPSTLSSRRRRKSPMTDEKLSYEAARDELLEVVRRLESGGVSLADSMELWQRGEKLADLCQSYLDGAREQVAQQRARSDREADADSKDPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGH9</accession>
    <name>A0A1Q2CGH9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_10750</name>
        <name evidence="10" type="ORF">SAMN05428934_102155</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY52747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10750"/>
    <dbReference type="EnsemblBacteria" id="AQP45214">
        <property type="protein sequence ID" value="AQP45214"/>
        <property type="gene ID" value="RPIT_10750"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY52747">
        <property type="protein sequence ID" value="SDY52747"/>
        <property type="gene ID" value="SAMN05428934_102155"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10750"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="183"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="244"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY52747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="447" mass="46686" checksum="77EB72D4EB345AE0" modified="2017-04-12" version="1">MSGPRRWGGLSLRLRLTLLTAGLLAVGLTLGAVALTAVVSSSRVAELDRAATARVETIARLASEDRLPDPLPVTQPGEIAQVLDAGGLVVSSSATASRTLPVLGADDAALAAERPGITLPTAYDDRARVVAGSTTWRGEPVTIVVALPLRDVEGVLRALRVSLVGVVPTLTLALAGVIWLALGRALRPVEELRVAAARVASEGGPGALPVPDADDELAALARTLNEMLDRLDRAASRQRRFVEDAAHELRSPLSSLRASVEVARSHPEAFPTGELAAELAPEVLRMQALVDDLLLLARVGATGGRRRPTNLRDVAEQVAATRRAGVAVDVTGEGEATVDGPAVERVVRNLVDNAVRHAGSRVRITVAGARVVVEDDGAGIAPEDRERVFERFVRLDEARQREAGGSGLGLAIAREIARDNGGDVVLGDSDLGGLRAELKLAGPLDGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGJ6</accession>
    <name>A0A1Q2CGJ6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Cupin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10915</name>
        <name evidence="3" type="ORF">SAMN05428934_102121</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY51681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10915"/>
    <dbReference type="EnsemblBacteria" id="AQP45242">
        <property type="protein sequence ID" value="AQP45242"/>
        <property type="gene ID" value="RPIT_10915"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY51681">
        <property type="protein sequence ID" value="SDY51681"/>
        <property type="gene ID" value="SAMN05428934_102121"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10915"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="43"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY51681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="113" mass="11968" checksum="EAB83C4AB7C7E6D2" modified="2017-04-12" version="1">MAKTTPVTGSSAHLDLAGALPVVPESTTSRVLVNNDLMRVVQFTFDAGEMLTEHSSPRAVVVQLVTGRMRFTVDGAEHTMGEGDIIYLAPGASHALVAETPCRMTLVMVDTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGM7</accession>
    <name>A0A1Q2CGM7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">UTP--glucose-1-phosphate uridylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_11055</name>
        <name evidence="5" type="ORF">SAMN05428934_10293</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDPGP type 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY50805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11055"/>
    <dbReference type="EnsemblBacteria" id="AQP45266">
        <property type="protein sequence ID" value="AQP45266"/>
        <property type="gene ID" value="RPIT_11055"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY50805">
        <property type="protein sequence ID" value="SDY50805"/>
        <property type="gene ID" value="SAMN05428934_10293"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11055"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003983">
        <property type="term" value="F:UTP:glucose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006011">
        <property type="term" value="P:UDP-glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00897">
        <property type="entry name" value="UGPase_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002618">
        <property type="entry name" value="UDPGP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016267">
        <property type="entry name" value="UDPGP_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43511">
        <property type="entry name" value="PTHR43511"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01704">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000806">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="362"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000806-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000806-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY50805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="458" mass="50280" checksum="93F06993A99CB59F" modified="2017-04-12" version="1">MSKEGLAAARAKMEEAGVSTPAIEVFTRFYELLESGETGIIREDSIEPLLDPPMLADVDITDLQAREAIQKTVIIKLNGGLGTSMGLDKAKTLLEVRDGNNFLDLLAQQVLAARERYDARLPLLLMNSFRTEADTLDYLSKYPELPVGDLPLSFMQNQEPKLRADDLTPVEWPADPTLEWCPPGHGDLYPALEGSGVLDALLEAGFRYACVSNGDNLGAAPNATIAGWFAQSGAPYAAELCRRTINDKKGGHLAVRKSDGQLILRDTAQTASEEMEFFTDEHRHPFFHTNNLWFDLQVLRETLTERGSVLGLPLIRNEKTVDPSDSSSTPVIQVESAMGAAIEVFEGATAICVGRDRFLPVKTTNELLLLRSDVYELNDEGRLIARTSSTPEIDLDSRYYKKVDKFEQRIPVAPSLRRATSLKVTGDWTFGPGVKVVGDVTLPDEGEGQQVPAGTTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGP1</accession>
    <name>A0A1Q2CGP1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Copper homeostasis protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Copper homeostasis protein CutC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11185</name>
        <name evidence="3" type="ORF">SAMN05428934_10267</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CutC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY50036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11185"/>
    <dbReference type="EnsemblBacteria" id="AQP45289">
        <property type="protein sequence ID" value="AQP45289"/>
        <property type="gene ID" value="RPIT_11185"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY50036">
        <property type="protein sequence ID" value="SDY50036"/>
        <property type="gene ID" value="SAMN05428934_10267"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11185"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005627">
        <property type="entry name" value="Cu_homeostasis_CutC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036822">
        <property type="entry name" value="CutC_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12598">
        <property type="entry name" value="PTHR12598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03932">
        <property type="entry name" value="CutC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110395">
        <property type="entry name" value="SSF110395"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY50036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="236" mass="25532" checksum="16B7775E54A65E5E" modified="2017-04-12" version="1">MSLLEVIALHAADAERAEAGGADRIELLGTMDDDGLSPEPRLVDKVRRATSIQIRPMVRLRPGFGTDGGEVTRMQGLIAAYLDAGADGVVLGFLNGLNRIDSEVVSELVGDGDFPWTFHRAIDHCLDADRAWKAVRALPRVDQVLTAGSVRGVEHGLDDLLRRARADADVARLIMAGGGLTPEHVPWLVRAGVRSFHIGSPARPGGSFKAYVDSELVSSWRDLIDDEAAHARHVHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGR0</accession>
    <name>A0A1Q2CGR0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CarD family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, CarD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11300</name>
        <name evidence="3" type="ORF">SAMN05428934_10243</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
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    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP45308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11300"/>
    <dbReference type="EnsemblBacteria" id="AQP45308">
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    </dbReference>
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        <property type="gene ID" value="SAMN05428934_10243"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CarD_TRCF" evidence="1">
        <location>
            <begin position="2"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY49349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="161" mass="17959" checksum="92E10569F80F5CB2" modified="2017-04-12" version="1">MTFSIGETVVYPNHGTAVIEDIENKTIKGEDKLYLVLRVIGQNDLVISVPACNLDLVGVRDVVDADGLEQVFSVLRAEHTEEPSNWSRRFKANMEKLHSGNVIKVSEVVRDLWRRDRDKGLSAGEKRMLAKARSILVAELALAEKVDEDKAEVMLDEVLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGR1</accession>
    <name>A0A1Q2CGR1_9ACTN</name>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_11210</name>
        <name evidence="2" type="ORF">SAMN05428934_10262</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP45294">
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        <property type="gene ID" value="RPIT_11210"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY49892"/>
        <property type="gene ID" value="SAMN05428934_10262"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR021678">
        <property type="entry name" value="DUF3263"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11662">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY49892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="91" mass="10633" checksum="4099A5082943719C" modified="2017-04-12" version="1">MSQATTFAHGVELSARDAAVLDFEDGWYKSPVPKEQAIMERFQLTSTKYYQLLNALIDAPEALEYKPLLVKRLRRERSRRQQLRSARRLHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGR6</accession>
    <name>A0A1Q2CGR6_9ACTN</name>
    <protein>
        <submittedName>
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        </submittedName>
        <submittedName>
            <fullName evidence="2">TatD DNase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10955</name>
        <name evidence="2" type="ORF">SAMN05428934_102112</name>
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    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY51417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10955"/>
    <dbReference type="EnsemblBacteria" id="AQP45250">
        <property type="protein sequence ID" value="AQP45250"/>
        <property type="gene ID" value="RPIT_10955"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY51417">
        <property type="protein sequence ID" value="SDY51417"/>
        <property type="gene ID" value="SAMN05428934_102112"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004536">
        <property type="term" value="F:deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015991">
        <property type="entry name" value="Hydrolase_TatD-type"/>
    </dbReference>
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        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TIGR00010"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY51417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="286" mass="30857" checksum="EC25BA9CC1C2BE0B" modified="2017-04-12" version="1">MNLPDGLPRLPDPLPRPVIDNHTHLTSTLEYSGLDVGASIELAASVGVTRIIEVGCDVASARAAVEIASAHPSVAVAVALHPNDAARAYLKGGEGRLNSELAAIEELVSHPRVVSVGETGLDYYRTREPEARAAQEKAFRRHIGWAKDHGKTLMIHDRDAHDDILRVLDSEGAPDGFVMHCFSGDADFAAQCLQRGAYLSFPGVVTFGSADNLREAALATPMDRIMVETDAPYLTPKPERGRPNAPYLLPHTVRFLADLLDVDLAEFCDQLVTNTLAAYGEWGSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGV0</accession>
    <name>A0A1Q2CGV0_9ACTN</name>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_08150</name>
        <name evidence="8" type="ORF">RPIT_11520</name>
        <name evidence="9" type="ORF">SAMN05428934_1282</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000028">
        <property type="protein sequence ID" value="SDZ23942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44774">
        <property type="protein sequence ID" value="AQP44774"/>
        <property type="gene ID" value="RPIT_08150"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45348">
        <property type="protein sequence ID" value="AQP45348"/>
        <property type="gene ID" value="RPIT_11520"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ23942">
        <property type="protein sequence ID" value="SDZ23942"/>
        <property type="gene ID" value="SAMN05428934_1282"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08150"/>
    <dbReference type="KEGG" id="tfl:RPIT_11520"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="16"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="104"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ23942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="170" mass="19398" checksum="9FA96AB7F914A3D9" modified="2017-04-12" version="1">MTEHQVDEAIGFERFVARRGRDLWRAAWLLTNDSQHAEDLVQTALAKTWGRYDAIGNDAQFEAYVRTTIYRTFVSWWRKMSWRNERPSETLADSASAEGSAHLRMDLMRALDELPRMQRAVLVLQYFEDLSIDEIAKQLGVSSGTVKTHSSRGRAALRDSAHLIEAGVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGZ2</accession>
    <name>A0A1Q2CGZ2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycine betaine/proline transport system substrate-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Glycine/betaine ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_11750</name>
        <name evidence="5" type="ORF">SAMN05428934_106125</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11750"/>
    <dbReference type="EnsemblBacteria" id="AQP45389">
        <property type="protein sequence ID" value="AQP45389"/>
        <property type="gene ID" value="RPIT_11750"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93445">
        <property type="protein sequence ID" value="SDY93445"/>
        <property type="gene ID" value="SAMN05428934_106125"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11750"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007210">
        <property type="entry name" value="ABC_Gly_betaine_transp_sub-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04069">
        <property type="entry name" value="OpuAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544494" evidence="2">
        <location>
            <begin position="24"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="OpuAC" evidence="3">
        <location>
            <begin position="43"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY93445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="300" mass="32825" checksum="A669966A2877BDD5" modified="2017-04-12" version="1">MFTTGIRKFGIAALGVAMTATMAACGTDDTTETGTTGTEDKGTITLGFIPSWTDGRSTAYLLENKLEEMGYEVEMEELSEPGPLYAGLAQGDIDMYPSAWPEVTHASFMEEYSDSIEDLGSYYDNAKLTWAVPEYSEITSIEDIPDYADALDSRIIGIEPGAGLTKASQEQVIPQYGLDDWELVTSSTTAMLAELSKAVDNEEEIVVTLWRPFWANSEFGMRDLEDPEGALGEAEGLHFLARSGFSEDHPEAAEWISELQLNDEQYGALEDTVVNQYEEGQEAEAIEAWLEGNADVLPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGZ6</accession>
    <name>A0A1Q2CGZ6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Chaperone protein ClpB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">clpB</name>
        <name evidence="13" type="ORF">RPIT_11800</name>
        <name evidence="14" type="ORF">SAMN05428934_106115</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homohexamer. The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homohexamer; The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11800"/>
    <dbReference type="EnsemblBacteria" id="AQP45398">
        <property type="protein sequence ID" value="AQP45398"/>
        <property type="gene ID" value="RPIT_11800"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93196">
        <property type="protein sequence ID" value="SDY93196"/>
        <property type="gene ID" value="SAMN05428934_106115"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11800"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017730">
        <property type="entry name" value="Chaperonin_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03346">
        <property type="entry name" value="chaperone_ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 11" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Clp R" evidence="12">
        <location>
            <begin position="3"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="436"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP45398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY93196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="855" mass="92926" checksum="049A4D639371175F" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH00</accession>
    <name>A0A1Q2CH00_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Sorbitol-6-phosphate 2-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_11420</name>
        <name evidence="2" type="ORF">SAMN05428934_10220</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY48577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11420"/>
    <dbReference type="EnsemblBacteria" id="AQP45330">
        <property type="protein sequence ID" value="AQP45330"/>
        <property type="gene ID" value="RPIT_11420"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY48577">
        <property type="protein sequence ID" value="SDY48577"/>
        <property type="gene ID" value="SAMN05428934_10220"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11420"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY48577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="368" mass="37974" checksum="0C4AF82E7BBFE8D8" modified="2017-04-12" version="1">MTLLEIAPLVRGAYLARHGAPVLVSHTPGGGESPAQVRAGSADDLPAALAEAELPLPGGVVVEVGEEQVAFSVRTLGEVNRLPGARDTEARSAASRSAVVSGKVAVVTGGAQGFGAEIVHGLVDSGAFVYIADLNGDGASALAAEVGDHRAAAITVNVADEASVQAMAEQIAATTGGLDLVVSNAGIVRAGSVLEQDLSSFALTTDINYTAFFLVTKHLGRLLAAQHRTAPDWLTDVIQINSKSGLTGSNKNGAYAGSKFGGLGLVQSFALELVEHGVKVNAICPGNFYDGPLWSDPDKGLFVQYLRSGKVPGATTVDEVREFYESKVPLRRGTTGADVMRAVYYIVEQAYETGQAVPVTGGQVMLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH12</accession>
    <name>A0A1Q2CH12_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Glucose/arabinose dehydrogenase, beta-propeller fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_11780</name>
        <name evidence="5" type="ORF">SAMN05428934_106119</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11780"/>
    <dbReference type="EnsemblBacteria" id="AQP45394">
        <property type="protein sequence ID" value="AQP45394"/>
        <property type="gene ID" value="RPIT_11780"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93315">
        <property type="protein sequence ID" value="SDY93315"/>
        <property type="gene ID" value="SAMN05428934_106119"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11780"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544496" evidence="2">
        <location>
            <begin position="27"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="GSDH" evidence="3">
        <location>
            <begin position="78"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY93315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="406" mass="42083" checksum="2F5921F41CC29F85" modified="2017-04-12" version="1">MRKLAPVALATLALVACSGTPEPATAPPSTVGPTTSAPAASPSATTSATTAQSPSPATSAASAVPETHELEVTVHDTFDEPWAMAWLPGTDALVITERGGTMKLRDASGVREVSGVPEVVVAGQGGLGDVIPGPTFTTDGTVYLSWVEAGDGGTGAVVGTAKLDVSAAALSDVAVIWEQRPKVDGDGHFAHRLAIQDDHLFVSSGDRQKMDPAQELDSTLGKILRLTLDGQPAADNPFSGEDAPVAQQFYSMGHRNPLGLAFDADGRLWSTEMGPKGGDELNLIQPGANYGWPVASNGSHYGGGEIPDHTDGDGFEPPKVFWTPSISPGSLMIYQGTLFPAWTGDAFIGGLSGEVLIRVDLDGETATEAENWPMGSRIRALSEGPDGAIWVLEDGPGARLLELRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH21</accession>
    <name>A0A1Q2CH21_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 15">NAD(P) transhydrogenase subunit beta</fullName>
            <ecNumber evidence="6 15">7.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Nicotinamide nucleotide transhydrogenase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">RPIT_11890</name>
        <name evidence="19" type="ORF">SAMN05428934_10697</name>
    </gene>
    <organism evidence="18 20">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 20" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">RP1T</strain>
        </source>
    </reference>
    <reference evidence="19 21" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 21">RP1</strain>
        </source>
    </reference>
    <reference evidence="18" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 15">The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>H(+)(in) + NAD(+) + NADPH = H(+)(out) + NADH + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:47992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="7.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell inner membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 15">Belongs to the PNT beta subunit family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.1" evidence="6 15"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11890"/>
    <dbReference type="EnsemblBacteria" id="AQP45412">
        <property type="protein sequence ID" value="AQP45412"/>
        <property type="gene ID" value="RPIT_11890"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92819">
        <property type="protein sequence ID" value="SDY92819"/>
        <property type="gene ID" value="SAMN05428934_10697"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11890"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008750">
        <property type="term" value="F:NAD(P)+ transhydrogenase (AB-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012136">
        <property type="entry name" value="NADH_DH_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034300">
        <property type="entry name" value="PNTB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02233">
        <property type="entry name" value="PNTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000204">
        <property type="entry name" value="PNTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="8 15" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14 15 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0520">NAD</keyword>
    <keyword evidence="11 15" id="KW-0521">NADP</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 15" id="KW-1278">Translocase</keyword>
    <keyword evidence="10 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="PNTB" evidence="17">
        <location>
            <begin position="8"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR000204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="AQP45412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="SDY92819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="465" mass="49059" checksum="E73D927A433DE20F" modified="2017-04-12" version="1">MLSNFIDATYIAAGLMFILALAGLSRHETAKKGNALGIMGMAFALIATNFAIAYTDYANHNLQPESAVMLYAAIGIGAVIGIWRARKVEMTGMPELIALLHSFVGAAAVLVGYNVYLDNPNSDAFHSIEVYLGVFIGAVTFTGSIVAWGKLNGRFASKPLTLPARHWLNLGIVVALALLGWWFVASHSILPLIIATVLSLLLGIHLVAAIGGADMPVVVSMLNSYSGWAAAFSGFMLDMSVLVITGALVGASGAILSYIMCRAMNRSFISVILGGFGDDTSGSQGAEDGEHREASTMEVAEMLADSKSVIIVPGYGMAVAQAQYPVAELTEALQARGCRVRFGIHPVAGRLPGHMNVLLAEAHVPYDIVEEMDEINDDFSSTDVVLVIGANDTVNPAAEEPGLPISGMPVLKVWEAETVVVFKRSMSAGYAGVQNPLFFKDNTVMCFGDAKTSVSAINAALPVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH59</accession>
    <name>A0A1Q2CH59_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_11785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45395">
        <property type="protein sequence ID" value="AQP45395"/>
        <property type="gene ID" value="RPIT_11785"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11785"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="248" mass="26674" checksum="35FA7EA3068F76E5" modified="2017-04-12" version="1">MALALGRAAAWGGLTLVDPAKLEGSRHTAFWAACAGLGAVEMLASPGDGTLSLRARLMLAATTAGTVFVTRDWATRTDARLVRALRHVRVRHPRRWMAAFTAAGAFAAYLTELQPSPHDDVSVPLVEAPLPGGIRDLIASMLQAVDGYQREVLEAQLASATVLVEDPEWPLTILVDESLPGTLLGEFTWPVSAEFTRDGRTHRLYLDIVEGRLAVLGQYLADDLDSAVDVDWSWPAVSEVTIRPGAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHC6</accession>
    <name>A0A1Q2CHC6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF2202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_12445</name>
        <name evidence="5" type="ORF">SAMN05428934_104196</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY80436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45511">
        <property type="protein sequence ID" value="AQP45511"/>
        <property type="gene ID" value="RPIT_12445"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY80436">
        <property type="protein sequence ID" value="SDY80436"/>
        <property type="gene ID" value="SAMN05428934_104196"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12445"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01048">
        <property type="entry name" value="Ferritin_like_AB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019243">
        <property type="entry name" value="DUF2202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09968">
        <property type="entry name" value="DUF2202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544511" description="DUF2202 domain-containing protein" evidence="2">
        <location>
            <begin position="28"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2202" evidence="3">
        <location>
            <begin position="36"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY80436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="255" mass="27627" checksum="FB5EB8A2C1EB0750" modified="2017-04-12" version="1">MKATLRTIAVSVTAAGLAFSGAMVASADDTLDADEKASVAFSREEERLARDLYTEFGKLYDSVVWDRIARSEQRHFDAIGRLLTTYELDDPSAGLAAGTYSDATLQNLYDDWLADGKANEDAAFKAAIELEERDIADLKAQLKIVDDDAVENVYERLLKGSENHLAAFTRWSEGDQTMGQPGNRPNGNGPNRGNQQGQPGKGQPGQMGQREPGQMGPRADAPRAAQREDRPETCDGTGPQQDRKGGGPRGQGGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHH6</accession>
    <name>A0A1Q2CHH6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminodeoxychorismate synthase, glutamine amidotransferase subunit</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Aminodeoxychorismate/anthranilate synthase component II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12715</name>
        <name evidence="3" type="ORF">SAMN05428934_104144</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY78986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12715"/>
    <dbReference type="EnsemblBacteria" id="AQP45561">
        <property type="protein sequence ID" value="AQP45561"/>
        <property type="gene ID" value="RPIT_12715"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY78986">
        <property type="protein sequence ID" value="SDY78986"/>
        <property type="gene ID" value="SAMN05428934_104144"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12715"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00566">
        <property type="entry name" value="trpG_papA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY78986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="213" mass="22760" checksum="2FF8CE7361FA7FA8" modified="2017-04-12" version="1">MAAILVIDNYDSFVYNIVSYLAQIGAEVEVWRNDDPRFADDDWHARFDGVLLSPGPGTPEEAGVCVDVVRQLGGVKPLFGVCLGLQAMAVAYGGVVDRAPELLHGKTSPVFHEGKGVFAGLPSPVTTTRYHSLAMVEDTVPEVLEVTARTESGVIMAVRHRSLAVEAVQFHPESVLTEGGYQMLANWLAECGDTDAPVRAAGLSPLVTTDLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHI6</accession>
    <name>A0A1Q2CHI6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, XRE family with cupin sensor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12775</name>
        <name evidence="3" type="ORF">SAMN05428934_104132</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY78649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12775"/>
    <dbReference type="EnsemblBacteria" id="AQP45571">
        <property type="protein sequence ID" value="AQP45571"/>
        <property type="gene ID" value="RPIT_12775"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY78649">
        <property type="protein sequence ID" value="SDY78649"/>
        <property type="gene ID" value="SAMN05428934_104132"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12775"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="15"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY78649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="237" mass="25927" checksum="1B6412DA444D01C6" modified="2017-04-12" version="1">MSYELGSGNELGRRLRAAREVQNRSLRSLAAAIGVSPSLMSQVETGRTLPSLTTLYALVTELGISFDALLGREAPGSPPPAPAPVYRRREEFKHQAEAEGRAIDMDNGVRWERLSVFEGTDVEALRATYQPGASSSVEGKFMYHYGNEHLYLISGELTLHLDLDRHTIHAGDSVVFNAERPHLFVNASDEPAVGVWYIFGREAAARAALGSHHQLAAPPSDGKVHDALDVLHNFRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHK9</accession>
    <name>A0A1Q2CHK9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_12655</name>
        <name evidence="2" type="ORF">SAMN05428934_104155</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45550">
        <property type="protein sequence ID" value="AQP45550"/>
        <property type="gene ID" value="RPIT_12655"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY79316">
        <property type="protein sequence ID" value="SDY79316"/>
        <property type="gene ID" value="SAMN05428934_104155"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12655"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY79316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="242" mass="26226" checksum="B2D265528BA3E50F" modified="2017-04-12" version="1">MAMLRALGTTIDVDLNGSPIDEGEFTALWDRCLVEPAAMEASDVVETVHAEGNSSLVILTQHITHALIAARRGELLMLHAGAVAHQTTGRALAFVAPGGTGKSTLTRLLAREYGYLTDETVGLDPATLEIFPYPKPITWAAVKGEPKIEHAPDSFGLQAAPPRPWLGDLVVLRRTPDREPSFTELGVLDAIERLVPESSSVTSLPRPLHVLADVHRRAGCTLIEYGEADDILDWCRARLETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHL8</accession>
    <name>A0A1Q2CHL8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Protein-tyrosine-phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12985</name>
        <name evidence="3" type="ORF">SAMN05428934_10490</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45607">
        <property type="protein sequence ID" value="AQP45607"/>
        <property type="gene ID" value="RPIT_12985"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY77504">
        <property type="protein sequence ID" value="SDY77504"/>
        <property type="gene ID" value="SAMN05428934_10490"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12985"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LMWPc" evidence="1">
        <location>
            <begin position="77"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY77504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="205" mass="22783" checksum="9E6F1F8C2B9DC808" modified="2017-04-12" version="1">MAIDRNSVQRQLIEDLAYAYGDVFGDAEIESAFTEAWELLSSRATVQNFLPVLVARRAREQLMARAQAEGRVVKHVPELLFVCVHNAGRSQMAAALAEHLSARRVHVRSAGSMPVDEINPVVVEALRERGIALNTAYPKPLSNDMVHAADVIVTMGCGDACPIFPGRRYEDWEVRDPAGQPLDVVREIRDDIQARVTTLLREILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHP3</accession>
    <name>A0A1Q2CHP3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ATP-binding cassette, subfamily B</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">Multidrug ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_12895</name>
        <name evidence="12" type="ORF">SAMN05428934_104108</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12895"/>
    <dbReference type="EnsemblBacteria" id="AQP45593">
        <property type="protein sequence ID" value="AQP45593"/>
        <property type="gene ID" value="RPIT_12895"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY77985">
        <property type="protein sequence ID" value="SDY77985"/>
        <property type="gene ID" value="SAMN05428934_104108"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12895"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="224"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="247"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="66"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="420"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="453"/>
            <end position="460"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP45593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY77985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="662" mass="71690" checksum="8E56B35767FEFBF4" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHZ3</accession>
    <name>A0A1Q2CHZ3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Na(+)/H(+) antiporter NhaA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Sodium/proton antiporter NhaA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">nhaA</name>
        <name evidence="10" type="ORF">RPIT_13700</name>
        <name evidence="11" type="ORF">SAMN05428934_11159</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>2 H(+)(out) + Na(+)(in) = 2 H(+)(in) + Na(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29251"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13700"/>
    <dbReference type="EnsemblBacteria" id="AQP45731">
        <property type="protein sequence ID" value="AQP45731"/>
        <property type="gene ID" value="RPIT_13700"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12703">
        <property type="protein sequence ID" value="SDZ12703"/>
        <property type="gene ID" value="SAMN05428934_11159"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13700"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015081">
        <property type="term" value="F:sodium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006885">
        <property type="term" value="P:regulation of pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01844">
        <property type="entry name" value="NhaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023171">
        <property type="entry name" value="Na/H_antiporter_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004670">
        <property type="entry name" value="NhaA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30341">
        <property type="entry name" value="PTHR30341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06965">
        <property type="entry name" value="Na_H_antiport_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00773">
        <property type="entry name" value="NhaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0050">Antiport</keyword>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0915">Sodium</keyword>
    <keyword evidence="8" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="99"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="161"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="215"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="238"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="267"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="302"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="404"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP45731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDZ12703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="427" mass="44820" checksum="C292C0999DCB2615" modified="2017-04-12" version="1">MTTFDTREPGFGTRLREWVLRDTTAGILLIVAAAIGLIWANTPWREAYTALSETVVGPESLHLDLSLAKWAADGLLAIFFFTVGLELKHEFVAGSLRSLRLAAVPILAAVGGMIMPAIIFVGVVVAFGATEALHGWAIPTATDIAFAVAVLAIFGKGLPKALRLFLLTLAVVDDLLAIIIIAVFYTAAIHGLWLGVSLAAVAAFAFVVRTRRARWWILIPIALVAWAAMHASGVHATIAGVLLGFVVPAVAIHGEHHARTHDYVEKVAPFSNGIALPVFAFFSAGVTLVGGDGPLAVLGQPVVLAITGGLVVGKLVGVMGTTALVTRLTPLRLPDAIGLRDLMPIGFLTGIGFTVSLLIAELSYPAGSDQSDGARIAVLLGTIIAATLAALSLRWSASRARSRDMNEDGLPDVDTAPITGDENWADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI36</accession>
    <name>A0A1Q2CI36_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_14065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45788">
        <property type="protein sequence ID" value="AQP45788"/>
        <property type="gene ID" value="RPIT_14065"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14065"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008792">
        <property type="entry name" value="PQQD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041881">
        <property type="entry name" value="PqqD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05402">
        <property type="entry name" value="PqqD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="94" mass="10018" checksum="18C4D16ED8E309FA" modified="2017-04-12" version="1">MSEREPRWQVRGDVAWTGSGDRFVAMALATPEKQPLVLEGPAALIWQTLSEGPLAETDVVAQVAELAGIEPGVITDDVAAFLRQLEDAKLASCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI49</accession>
    <name>A0A1Q2CI49_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sugar transferase involved in LPS biosynthesis (Colanic, teichoic acid)</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">UDP-galactose phosphate transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13765</name>
        <name evidence="4" type="ORF">SAMN05428934_11147</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13765"/>
    <dbReference type="EnsemblBacteria" id="AQP45740">
        <property type="protein sequence ID" value="AQP45740"/>
        <property type="gene ID" value="RPIT_13765"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12469">
        <property type="protein sequence ID" value="SDZ12469"/>
        <property type="gene ID" value="SAMN05428934_11147"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13765"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Bac_transf" evidence="2">
        <location>
            <begin position="14"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ12469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="212" mass="23251" checksum="FFC3B4B53C312EF9" modified="2017-04-12" version="1">MSPEPGRRRYDALKRAIDVAAAAAGLVVTAPLQLALAAVVLKVHGRPVLFRQQRPGKDGVIFELAKFRSMRHPDAEHQTDEERLTGLGRFLRATSLDELPSLWNVLKGDMSLVGPRPLLVEYLPRYTPEQARRHEVRPGITGLAQVSGRNGVAWEDKFALDVQYVDNRSLALDLSILLRTLTAVVKREGISADGHATVSVFQGTAAGEGRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI59</accession>
    <name>A0A1Q2CI59_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_14045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14045"/>
    <dbReference type="EnsemblBacteria" id="AQP45784">
        <property type="protein sequence ID" value="AQP45784"/>
        <property type="gene ID" value="RPIT_14045"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14045"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="159" mass="17599" checksum="CD62D5A96B70873A" modified="2017-04-12" version="1">MVVDYDDFVSSRLAELPAADPDSVGWFVDSGFLFDGGRLVLKHPSNFDRMCGTSLIVRADLLRIPDTLDDVDETFVDRALGSHIFLKNDLAAVGTPMRPVAFPGAVYRIGYSDSTSPPKAILTAYLSPGRMLRRPKQWARNVRLLRLTSSIRGEFGLPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI77</accession>
    <name>A0A1Q2CI77_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transketolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transketolase subunit A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13875</name>
        <name evidence="3" type="ORF">SAMN05428934_11125</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13875"/>
    <dbReference type="EnsemblBacteria" id="AQP45760">
        <property type="protein sequence ID" value="AQP45760"/>
        <property type="gene ID" value="RPIT_13875"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12040">
        <property type="protein sequence ID" value="SDZ12040"/>
        <property type="gene ID" value="SAMN05428934_11125"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13875"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="1">
        <location>
            <begin position="10"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ12040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="281" mass="30504" checksum="489A7058EDD70E8D" modified="2017-04-12" version="1">MNSLELAWRIRRHGVEMTHLSGGSHIGSILSVADIVAVLYAGIANVRPEDPEWEDRDRVILSKGHAGASIYAALAERGFFDVEELRTHYSDGSRLSGHVSHKGVPGVDLSTGSLGHGLSVGAGMAYAAKKDGKAHRVFVILGDGECDEGSVWEAAMVANHYGLGNLVAIIDHNRMQSLDFCEDTIALHPFGDKWRAFGWNTIELDGHNHEALTAALEGCRGSDKPTVIIAETIKGKGISFMEQNILWHYRFPHEGEEYDGAVAELNAQRPLNGESVKASAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI95</accession>
    <name>A0A1Q2CI95_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized conserved protein YdhG, YjbR/CyaY-like superfamily, DUF1801 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14300</name>
        <name evidence="3" type="ORF">SAMN05428934_11242</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ14999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45832">
        <property type="protein sequence ID" value="AQP45832"/>
        <property type="gene ID" value="RPIT_14300"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ14999">
        <property type="protein sequence ID" value="SDZ14999"/>
        <property type="gene ID" value="SAMN05428934_11242"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14300"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014922">
        <property type="entry name" value="DUF1801"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08818">
        <property type="entry name" value="DUF1801"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1801" evidence="1">
        <location>
            <begin position="24"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1801" evidence="1">
        <location>
            <begin position="154"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ14999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="249" mass="27982" checksum="6CCD047E8B754D51" modified="2017-04-12" version="1">MPDNITRPTDSSVDEFLDSVTERRRHEARALIDMMRDISGEQPVLWGSSIIGFGTEHYRYDTGREGDQPGIGFSPRKASITIYFSEGFEHYGDELSRLGKHRASVSCLYLNKLADVDLDVLRSMLEASWHKQHEPLAKPTTVDEYIAQVPDAAREKFDDLRALVRGQLPEAEETLSYGIVGYRTGKGRARVYISGFKDHVAIYPVPSDESLPQELRAHIHGKGSIWFALDEPLPTGLIRRTVAALVEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI96</accession>
    <name>A0A1Q2CI96_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_13990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45775">
        <property type="protein sequence ID" value="AQP45775"/>
        <property type="gene ID" value="RPIT_13990"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13990"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="81" mass="8925" checksum="F34EA8F895D0B536" modified="2017-04-12" version="1">MQFVQARPALVRQLRSRESCRRSVRSLGCLPQRFAHVGVDQWEGIGDPSRAVASWAFERGNESSMMAASVDGARKVDSFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIA7</accession>
    <name>A0A1Q2CIA7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_14075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14075"/>
    <dbReference type="EnsemblBacteria" id="AQP45790">
        <property type="protein sequence ID" value="AQP45790"/>
        <property type="gene ID" value="RPIT_14075"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14075"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="139" mass="15196" checksum="3DBB087BEC0A9CDF" modified="2017-04-12" version="1">MADEHLTERQRAAKIRHELSQGNARAEAARAKVLIDEFIAAANEKGLAPRPLKATTLDGHVVKTDKVGWYLRTNHSVAIDTDGNYYSLVVPGGLKERLRGVKLTPTLAPLVIGRGGRDGETGDLKEFLDWTLNGTIPQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIC3</accession>
    <name>A0A1Q2CIC3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Multisubunit sodium/proton antiporter, MrpD subunit</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Na+/H+ antiporter subunit D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_14460</name>
        <name evidence="5" type="ORF">SAMN05428934_109124</name>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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            <strain evidence="4 6">RP1T</strain>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
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        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
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        </source>
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</entry>
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            <dbReference type="Proteomes" id="UP000199635"/>
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<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="306" mass="33442" checksum="914FBE9EBEBF38C5" modified="2017-04-12" version="1">MGTYVLRRVLQMIPVIFGTTFLIYWMVFSLGDPTVGRCGERPCPEAYVARIYQEYNLDKPLPEQYVRYMAKVAQGDLGTSFNGNEVSEQLGDRWPVTLRLATIAIMFEALIGIAAGLLAGLKRRSFWDSLVFVSTLVIISIPSFVLGSVAQMVFGVQLSWFPVTATQGTWGQLLLPGFVLGSLSMAYIARLTRNSLSENLSADYVRTAKAKGLSSGRVVGVHTFRNSLIPVVTFIGADFGALMGGALVTERIFNIPGIGGYIFHSITTKDATAVVGTITMLVLIFLLMNLIVDLLYGALDPRIAHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIP0</accession>
    <name>A0A1Q2CIP0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ig-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_14790</name>
        <name evidence="5" type="ORF">SAMN05428934_10962</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14790"/>
    <dbReference type="EnsemblBacteria" id="AQP45915">
        <property type="protein sequence ID" value="AQP45915"/>
        <property type="gene ID" value="RPIT_14790"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05761">
        <property type="protein sequence ID" value="SDZ05761"/>
        <property type="gene ID" value="SAMN05428934_10962"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14790"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd14947">
        <property type="entry name" value="NBR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032350">
        <property type="entry name" value="N_BRCA1_central"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16158">
        <property type="entry name" value="N_BRCA1_IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544520" evidence="2">
        <location>
            <begin position="21"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="N_BRCA1_IG" evidence="3">
        <location>
            <begin position="70"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ05761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="348" mass="35829" checksum="393AEBCF113FBD51" modified="2017-04-12" version="1">MTRRWVAVLTLCAFATGCSASFTLDGTSPTAPPQPTRAAGSTPAAESSAAATPDEADCAPDAALAGHLSTPDGTQLPSGTTFEKSWRLVNTGCGSWPEGTELIHLDGDLTSAGPAPTARPIVPGGTADITVSVTTPGEPGSYRGAWQLRAPDGRQFGTVLTSEIVTVADVTETGTVLVPLQPIPVFPSILAPEGFPPAGATPTADASGHPPSADADEVRRAVSLRVDLNVIDYNLVASDKTKKLIFIEPDIVLTSLRPTDTYTHELCAGGETSVRVVTELSLVDHVVHSRSAATLSVGSSCVTGTPQDTRVYNLVAGDGQTVATSGWGSVSGGAYDIAVSLTNEPWQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIR7</accession>
    <name>A0A1Q2CIR7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Error-prone DNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">RPIT_03950</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase type-C family. DnaE2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03950"/>
    <dbReference type="EnsemblBacteria" id="AQP46002">
        <property type="protein sequence ID" value="AQP46002"/>
        <property type="gene ID" value="RPIT_03950"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03950"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011708">
        <property type="entry name" value="DNA_pol3_alpha_NTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041931">
        <property type="entry name" value="DNA_pol3_alpha_thumb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040982">
        <property type="entry name" value="DNA_pol3_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023073">
        <property type="entry name" value="DNA_pol_error_prone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029460">
        <property type="entry name" value="DNAPol_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004805">
        <property type="entry name" value="PolC_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32294">
        <property type="entry name" value="PTHR32294"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32294:SF4">
        <property type="entry name" value="PTHR32294:SF4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07733">
        <property type="entry name" value="DNA_pol3_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17657">
        <property type="entry name" value="DNA_pol3_finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14579">
        <property type="entry name" value="HHH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00594">
        <property type="entry name" value="polc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="POLIIIAc" evidence="12">
        <location>
            <begin position="6"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="962"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1191"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="962"/>
            <end position="984"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP46002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="1262" mass="136909" checksum="BF9FACE3E8D7E37D" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIU6</accession>
    <name>A0A1Q2CIU6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Tryptophan synthase beta chain</fullName>
            <ecNumber evidence="11">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">trpB</name>
        <name evidence="13" type="ORF">RPIT_06435</name>
        <name evidence="14" type="ORF">SAMN05428934_103232</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 11">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the TrpB family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06435"/>
    <dbReference type="EnsemblBacteria" id="AQP46056">
        <property type="protein sequence ID" value="AQP46056"/>
        <property type="gene ID" value="RPIT_06435"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71105">
        <property type="protein sequence ID" value="SDY71105"/>
        <property type="gene ID" value="SAMN05428934_103232"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06435"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06446">
        <property type="entry name" value="Trp-synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00133">
        <property type="entry name" value="Trp_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006653">
        <property type="entry name" value="Trp_synth_b_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006654">
        <property type="entry name" value="Trp_synth_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023026">
        <property type="entry name" value="Trp_synth_beta/beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001413">
        <property type="entry name" value="Trp_syn_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00263">
        <property type="entry name" value="trpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00168">
        <property type="entry name" value="TRP_SYNTHASE_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="PALP" evidence="12">
        <location>
            <begin position="55"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="11">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP46056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY71105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="411" mass="43565" checksum="1601C932914EEAFB" modified="2017-04-12" version="1">MSTPDATGHFGRFGGRFVPEALQAALNELTEAFAQAQADPSFTAELARLQRDYSGRPTPITEADSFSKECGNARVLLKREDLNHTGAHKINNVLGQALLTKRMGKTRVIAETGAGQHGVATATAAALLGLECRVYMGEVDTQRQAVNVARMQLLGAEVHAVAAGSRTLKDAMNEAMRDWVTTVDTTHYLIGTVGGPHPFPYLVRELQRVISTEARQQMLDDHGALPDYVAACVGGGSNAIGMFADFIPDESVALYGFEAEGEGIMSGRHAATISAGTPGVLHGARTYVLQDEDGQTIESHSISAGLDYPGVGPEHAHLAQTGRAIYEPVTDADAMEAFRLLTRTEGIIPAIETAHALAGAMRLGRRIAEEDPSARPTILVCLSGRGDKDVATAFDYFGLSGQPDAIVGGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIU7</accession>
    <name>A0A1Q2CIU7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Cell division protein FtsX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">RPIT_05300</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Part of the ABC transporter FtsEX involved in cellular division.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05300"/>
    <dbReference type="EnsemblBacteria" id="AQP46032">
        <property type="protein sequence ID" value="AQP46032"/>
        <property type="gene ID" value="RPIT_05300"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05300"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004513">
        <property type="entry name" value="ABC_transpt_FtsX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040690">
        <property type="entry name" value="FtsX_ECD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47755">
        <property type="entry name" value="PTHR47755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18075">
        <property type="entry name" value="FtsX_ECD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003097">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="10 14" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="201"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX_ECD" evidence="13">
        <location>
            <begin position="37"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="12">
        <location>
            <begin position="188"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR003097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF18075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="AQP46032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="283" mass="30329" checksum="10E89D4FF7FBA3BE" modified="2017-04-12" version="1">MTIAVIVTMGVSLSLLGAGLLTAMEVNLAKSSLYDKIEISVFLCTEKSQGGRCEAGKGTTDAQREQIQQTLESNPEVSEVVYQSKEEAFAEFQRVFAESPVVASRTAEDMQDSFSIKLVNPENFAGVVSEAKGLQGVQNVQDLHTVLEPMFKWLGALQWATISMSALLLLAAALQIANTIRMAAFTRRREIGIMRLVGASNIYILLPFLLEALIAGLIGVLIAAGALTAGFYAIIVQNAQTSITALPWIGWGDLITAILSVAAVGVALAVIPTLLATRKYLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIZ5</accession>
    <name>A0A1Q2CIZ5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_07270</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07270"/>
    <dbReference type="EnsemblBacteria" id="AQP46074">
        <property type="protein sequence ID" value="AQP46074"/>
        <property type="gene ID" value="RPIT_07270"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07270"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="85"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="146"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP46074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="371" mass="39480" checksum="B65ABD44795BCEEC" modified="2017-04-12" version="1">MRWGTRTFLTQALVVAVGVITAALIAVVVGPPLFHEHLQQLGHADGTAEMGHVEQAFLDAGVRSLGIGLVVALTLAIGLAWIETRRLRRPLEQLTAAAAQLEAGDYTARVPQSGTSPEFTAVADAFNDMASRLDSTETSRRRLLSDVAHELRTPLATLTAELEAVIDDVVPWDHDSQQLLTLQAARLKKIAADLDDVSRAEEGRFTLDTQTQAVWDLIEPAVATVATRYQAKGVVLSADSDPGFVAADPQRVGQILGNLLDNALRHTPIGGIVHISARESRDEVVFMVTDTGDGLTPEQLSKVFDRFYRADTARARDAGGSGIGLTIARSLALAHGGSLTATSPGPGHGSTFTLTLPLATAPEPERVLIDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ22</accession>
    <name>A0A1Q2CJ22_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAD(P)H-quinone dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_09700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="2">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09700"/>
    <dbReference type="EnsemblBacteria" id="AQP46111">
        <property type="protein sequence ID" value="AQP46111"/>
        <property type="gene ID" value="RPIT_09700"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09700"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="4">
        <location>
            <begin position="3"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="3">
        <location>
            <begin position="346"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="182"/>
            <end position="189"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP46111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="467" mass="48993" checksum="540EB3EA069F7FD3" modified="2017-04-12" version="1">MTKVVIIGGGPGGYEAALVGNQLGGEVTLIERDGLGGAAVLTDCVPSKTLVATAEVMVRIENARQLGLHIAAADVSEVVRVDLGEVNQRVLNLAGAQSSDITNRLRQDGVEIVSGTARLEGPTTVVASTPDGERTYDADIVLLATGTTPRELPDAQCDGERILNWKQVYNLTEVPERLIVVGSGVTGAEFASAYDGLGCDVVLVSSRTQVLPGEDQDAAAVLQRAFERRGMEIMSECRAVAARREGDGVVVTLEDGREVHGSHCLMAVGSIPNSAGLGLESVGVEMTPSGHIVVDRVSRTSVRNIYAAGDVTGVFALASVAAMQGRIAMWHSLGDAVAPLDLRNVSSNVFTTPEIATVGVTQKEVDAGEVRVASVLLPLGPNARSKMQGFTDGFVKLFCLPTTGIIIGGVVVAPRASELIHSISLAVSQRMTVDDFSHAFTVYPSMSGSVAEAARRLHHRGEDLLTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ30</accession>
    <name>A0A1Q2CJ30_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sodium/proton antiporter, CPA1 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Sodium:proton antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_10320</name>
        <name evidence="7" type="ORF">SAMN05428934_102241</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10320"/>
    <dbReference type="EnsemblBacteria" id="AQP46121">
        <property type="protein sequence ID" value="AQP46121"/>
        <property type="gene ID" value="RPIT_10320"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55347">
        <property type="protein sequence ID" value="SDY55347"/>
        <property type="gene ID" value="SAMN05428934_102241"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10320"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006812">
        <property type="term" value="P:cation transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="278"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="399"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="5">
        <location>
            <begin position="18"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP46121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY55347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="641" mass="68174" checksum="B44B0C65871F7FA1" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ77</accession>
    <name>A0A1Q2CJ77_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC-type antimicrobial peptide transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_13345</name>
        <name evidence="11" type="ORF">SAMN05428934_10418</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY75448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13345"/>
    <dbReference type="EnsemblBacteria" id="AQP46167">
        <property type="protein sequence ID" value="AQP46167"/>
        <property type="gene ID" value="RPIT_13345"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY75448">
        <property type="protein sequence ID" value="SDY75448"/>
        <property type="gene ID" value="SAMN05428934_10418"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13345"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="21"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="348"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP46167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY75448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="452" mass="48693" checksum="349E4601BC7189FC" modified="2017-04-12" version="1">MRWSDLLAASFASLRQRLFRTSLTVLGVLIGTTAVIVMVSLGVGLSSSFTAQFQNINLRQVQVYAPPPVEQGMQGVPTKMNDAMLAYLETMPGAQDVWPVYYADMEMSIGSGQQFMQIQGLPAEAFPEMDLTLAWGELPHAGSFSLLLGDMVHEQFWDPMTGMPLEIDFRTQTLFGTLTTWGDYGPVPIPGDDGPVGEDPTQPPPPKKRHILPVAGQLLNDRGEGQWGPNSMMVWADLDAMVKWMQKALPGKALPNQPATSDGKPLGKEFIYSEFRVLTQDPEAAEAMLNSLREQGIQANAEVEWIRQAQSQAVVVQAVFGGIGFISLLVAAIGIANTMMMSVYERTKEIGIMKVMGAALGDIRKMFLIESAAIGFIGGITGLLLSVAVSAILNATLGSMMGEMGGEAQLSVIPIWLMVGAVAFATLIGMLAGMVPAQRAMKLSPLAAIRNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJA6</accession>
    <name>A0A1Q2CJA6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP46184">
        <property type="protein sequence ID" value="AQP46184"/>
        <property type="gene ID" value="RPIT_14000"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14000"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025948">
        <property type="entry name" value="HTH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13276">
        <property type="entry name" value="HTH_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13683">
        <property type="entry name" value="rve_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="117"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="316" mass="36014" checksum="5EB3FFD7942B2561" modified="2017-04-12" version="1">MIRREAGMSTARFVKLIDMPERTWRRWQAKARQDRRPKGPWPQPARTAARDLVVGHALAKPAWGHRKIWALTRHAGHEVSQATVLRLLRDEGLLLASEYQKQRRDLAADRRAAFAKTPDGPNQVWQLDFSEFETTSGGTWRIAGCRDWYSKYEHPWHVSPTGNKHDAIAAVELALADYEALFGHPLAEACPIDEVTGEVLPVVTIVTDNGGPFRSLDFELFITSHPELQHVRTRVKSPGQNGSRERGFGTLKYERLFLDEIADALTLVERAEDYRIEYNTQRPHEAIAWNRPLEVHLGRASTTTPTFEQEEILPTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBC6</accession>
    <name>A0A1Q2CBC6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Precorrin-2 dehydrogenase</fullName>
            <ecNumber evidence="3">1.3.1.76</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_00045</name>
        <name evidence="7" type="ORF">SAMN05428934_10936</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>NAD(+) + precorrin-2 = 2 H(+) + NADH + sirohydrochlorin</text>
            <dbReference type="Rhea" id="RHEA:15613"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58351"/>
            <dbReference type="ChEBI" id="CHEBI:58827"/>
            <dbReference type="EC" id="1.3.1.76"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; siroheme biosynthesis; sirohydrochlorin from precorrin-2: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.76" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00045"/>
    <dbReference type="EnsemblBacteria" id="AQP43411">
        <property type="protein sequence ID" value="AQP43411"/>
        <property type="gene ID" value="RPIT_00045"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05294">
        <property type="protein sequence ID" value="SDZ05294"/>
        <property type="gene ID" value="SAMN05428934_10936"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00045"/>
    <dbReference type="UniPathway" id="UPA00262">
        <property type="reaction ID" value="UER00222"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004325">
        <property type="term" value="F:ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043115">
        <property type="term" value="F:precorrin-2 dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028161">
        <property type="entry name" value="Met8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006367">
        <property type="entry name" value="Sirohaem_synthase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35330">
        <property type="entry name" value="PTHR35330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01470">
        <property type="entry name" value="cysG_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ05294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="160" mass="16977" checksum="FA11D66A0732A908" modified="2017-04-12" version="1">MSAPNDHEPGSPAYLAGLLLRNRDVLVVGAGHVAERRLRRLLEVGASVRVVAPEATKAIAALDEEGLVAWRARPFVDDDLDGAWYVIAATDSAEVNAAVASGAEARHTFCVRSDEAFGGSAWTPATYNVQDLTVAVIGNRDPQRSKAVREAIRQSLGDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBX7</accession>
    <name>A0A1Q2CBX7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HAD family hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Haloacid Dehalogenase Superfamily Class (Subfamily) IIA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01265</name>
        <name evidence="4" type="ORF">SAMN05428934_1082</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAD-like hydrolase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ00919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01265"/>
    <dbReference type="EnsemblBacteria" id="AQP43614">
        <property type="protein sequence ID" value="AQP43614"/>
        <property type="gene ID" value="RPIT_01265"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ00919">
        <property type="protein sequence ID" value="SDZ00919"/>
        <property type="gene ID" value="SAMN05428934_1082"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01265"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000915">
        <property type="entry name" value="PGP-type_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="14"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ00919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="267" mass="29169" checksum="C8072510DD6F4537" modified="2017-04-12" version="1">MGTPTRWYDAYVFDLDGTIFLGDELLPGAVDVVAKLRAEGKAVKFLSNNATNDPAMYCDKLQRMGLAVPVSDIVNTIVTTVRWLSGHHPDAALFVIGEEPLQRALLEAGFRLTDDAGEIDIVVASYDRAFDYRKLQIAFDAIWFHERAFLIQTNPDRFCPYPGGRGEPDCAAMTAAIEAATGTRCRVSLGKPSPLMLTEALRGHDVDLSQCLMVGDRLATDIQMALDCGMPSALVLTGDSTLDDVSARPHDQRPTYVVEGLSQLLPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC00</accession>
    <name>A0A1Q2CC00_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">T2SSF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_01415</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01415"/>
    <dbReference type="EnsemblBacteria" id="AQP43638">
        <property type="protein sequence ID" value="AQP43638"/>
        <property type="gene ID" value="RPIT_01415"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01415"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="7">
        <location>
            <begin position="75"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP43638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="209" mass="21969" checksum="40282BBB9E788AA4" modified="2017-04-12" version="1">MRHPPGWLRDRPGGMRLRDRMALAVLAGLAVAGGAGGAVGVLLGVFSVPLVFGGVSLWRSPRPTGRRHSELPDALDFLAVCLEAGLPVTAATETVAAVSPEETRLTLQGVASHLALGRAGAEAWGSLRDDPVWGRAAADIVRSERSGTALVAVLRMHADDARRELRDEATKKARTVGVRSAVPLMVCFLPAFVLVGVVPIVAGLMTKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC15</accession>
    <name>A0A1Q2CC15_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-galactosidase</fullName>
            <ecNumber evidence="3">3.2.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lactase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_01075</name>
        <name evidence="9" type="ORF">SAMN05428934_105166</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01075"/>
    <dbReference type="EnsemblBacteria" id="AQP43585">
        <property type="protein sequence ID" value="AQP43585"/>
        <property type="gene ID" value="RPIT_01075"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87877">
        <property type="protein sequence ID" value="SDY87877"/>
        <property type="gene ID" value="SAMN05428934_105166"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01075"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009341">
        <property type="term" value="C:beta-galactosidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901575">
        <property type="term" value="P:organic substance catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004199">
        <property type="entry name" value="B-gal_small/dom_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006101">
        <property type="entry name" value="Glyco_hydro_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023230">
        <property type="entry name" value="Glyco_hydro_2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006104">
        <property type="entry name" value="Glyco_hydro_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032312">
        <property type="entry name" value="LacZ_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02929">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16353">
        <property type="entry name" value="DUF4981"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02837">
        <property type="entry name" value="Glyco_hydro_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00132">
        <property type="entry name" value="GLHYDRLASE2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01038">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="SSF49303"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00719">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bgal_small_N" evidence="7">
        <location>
            <begin position="710"/>
            <end position="991"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP43585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY87877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="994" mass="110132" checksum="C151586C539064D3" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC25</accession>
    <name>A0A1Q2CC25_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_01550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01550"/>
    <dbReference type="EnsemblBacteria" id="AQP43659">
        <property type="protein sequence ID" value="AQP43659"/>
        <property type="gene ID" value="RPIT_01550"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01550"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022454">
        <property type="entry name" value="CHP03883_F420-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018766">
        <property type="entry name" value="Zinicin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042271">
        <property type="entry name" value="Zinicin_2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39420">
        <property type="entry name" value="PTHR39420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10103">
        <property type="entry name" value="Zincin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03883">
        <property type="entry name" value="DUF2342_F420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03624">
        <property type="entry name" value="TIGR03624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="328" mass="36355" checksum="3AAF4FA1C8A7B9D9" modified="2017-04-12" version="1">MWLLMDYAPPVSWDLARRVARRAAGQLPDIDPRELDMLTADLRVTARRAGELAAAHLGLESVGATSVRVVDWAGWSRAARHMAEAVVGELSLTPRPAGVGSALRGLGNGLLAGLAMGRVSRQLLGQYDAVTGDDALYLVAPTILQHERRHAFVPEHFRLWVALHEQTHALQFRAAPWLRDYVRERMAVVADDEVQIAEALIAWQETGDLVSLLVSREAHTQLHELTALMTLLEGHADLVSDTVGCRHATTVGKMRKAFARPQRTGRLANASATLDKQAQYRDGLAFCRTVVRRRSWKFLSRAFADPGNLPTMSEISDPQAWIDRQRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC55</accession>
    <name>A0A1Q2CC55_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Broad specificity phosphatase PhoE</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Histidine phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_01705</name>
        <name evidence="2" type="ORF">SAMN05428934_10889</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01705"/>
    <dbReference type="EnsemblBacteria" id="AQP43682">
        <property type="protein sequence ID" value="AQP43682"/>
        <property type="gene ID" value="RPIT_01705"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02613">
        <property type="protein sequence ID" value="SDZ02613"/>
        <property type="gene ID" value="SAMN05428934_10889"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01705"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ02613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="220" mass="24666" checksum="6C57E699BD61E567" modified="2017-04-12" version="1">MNVAEQSIVHVMRHGQVENPGGVLYGRLPGYGLSELGHEMARRMGEFWRDVPLTHLRCSPLQRAQETLAPTAAQHPHLEVVTDPRVIEAENKFEGMVFGKDNRALRDPKMFWHMRNPLQPSWGEPYKEIAARMMAAIRDAAEAAGPGGQALIVSHQLSIWMARRFAEGRSLVHDPRRRECTLCSVTSFTLRDGLVTAVGYQEPVADLLPVKHGRKFKVGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC99</accession>
    <name>A0A1Q2CC99_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl-CoA hydratase 2</fullName>
            <ecNumber evidence="1">4.2.1.119</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Enoyl-CoA hydratase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_01935</name>
        <name evidence="8" type="ORF">SAMN05428934_11617</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a (3R)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:26526"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57319"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="EC" id="4.2.1.119"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="4.2.1.119" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000016">
        <property type="protein sequence ID" value="SDZ20433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01935"/>
    <dbReference type="EnsemblBacteria" id="AQP43721">
        <property type="protein sequence ID" value="AQP43721"/>
        <property type="gene ID" value="RPIT_01935"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ20433">
        <property type="protein sequence ID" value="SDZ20433"/>
        <property type="gene ID" value="SAMN05428934_11617"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01935"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005835">
        <property type="term" value="C:fatty acid synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003965">
        <property type="entry name" value="Fatty_acid_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039569">
        <property type="entry name" value="MaoC-like_dehydrat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13452">
        <property type="entry name" value="MaoC_dehydrat_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01483">
        <property type="entry name" value="FASYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MaoC_dehydrat_N" evidence="6">
        <location>
            <begin position="55"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="MaoC-like" evidence="5">
        <location>
            <begin position="185"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ20433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="285" mass="31052" checksum="3CBA5822CB3FB7E3" modified="2017-04-12" version="1">MSRDVQVLPTLPKVEGLWLKAAKGLLKRPGERSQLPDRTLMVLDHTQSVLGLADYARVTGFALRDSVPATWLHVLTFPLQTELMAAEDFPFPLAGLVHVTNEMTLHRPVAVGEKLRISVRAEDLQPHAKGATYAMRGEVHAGDELVWDGTSTYLATGVKMSGEAPPAVRLEAPDVTPSQQWRLGPDLGRQYADVSGDANPIHLTPLTARLFGFPRPIIHGMWTHARAVAALGGKLPEAYSVRVQFAKPIFLPGKVGFASEREGDGWRFAVVNKDGKPHLVGELTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCF3</accession>
    <name>A0A1Q2CCF3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_02235</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02235"/>
    <dbReference type="EnsemblBacteria" id="AQP43777">
        <property type="protein sequence ID" value="AQP43777"/>
        <property type="gene ID" value="RPIT_02235"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02235"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010359">
        <property type="entry name" value="IrrE_HExxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06114">
        <property type="entry name" value="Peptidase_M78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="3">
        <location>
            <begin position="11"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="372"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="398" mass="43686" checksum="CEF9867469FBD30E" modified="2017-04-12" version="1">MIDSASVGERVRRLRVATGLSQTELSRQLGMAGNAVVSKLETGRLAPDEGLLRALADRLGCTTHYLSRSGFDGVSTRPWLRAYADASAKVVDSVLADNLVAYEFIDGVGLHRVPDSLPLMVGDPNDEDAIEEFAGEVRAAAEIPEGGVVRNVIRAAERVGCTVLPMDSELGRHLGLSQRIDGRPFVRVAGPGRTGVPGDRQRFTVAHEIGHLAMHSELAPPRTPDEAKRLENQAHRFAAAFLTPAAPLLDDWHTSAGGRVTLGALQRLKMTWGVAIKMLVTRFRQLEVIDDDHARSLYRQISARGWNRNEPVEVSAETAIWLTKALSKAFPRTDLHHSIHLAAAHHGLDARYVASWTTWANDASTVIRLDRRPQDPEPAQTPPQQLAEVVHLPRNRQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCR5</accession>
    <name>A0A1Q2CCR5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione-dependent reductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Putative glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_03005</name>
        <name evidence="4" type="ORF">SAMN05428934_101202</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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            <strain evidence="3 5">RP1T</strain>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 6">RP1</strain>
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            <end position="289"/>
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        <location>
            <position position="188"/>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
    <sequence length="318" mass="36724" checksum="0A60CBE5C5D0989F" modified="2017-04-12" version="1">MSERNEHSKGGVYSVKGKEFNRDSRYIETRIVAEPREGTDDYPVEPHRYRLVAAYACPWANRAIIVRDLLGLDQVISMGNPGPTHDEDSWTFDLDPGGVDPVLGIAKLKEAYERRFPGYDRGITVPAIVDETTGEVVTNNFPQITEDFYVEWKQFHKADAPNLWPDELRDEMDDVMQRIYTEVNNGVYRCGFAGSQEAYDAAYDRLWTAMDWLEERLAERRYLMGEQITEADVRLFTTLVRFDPVYHGHFKCNRNKLTEMPNLWGYARDLFQTPGFGDNVDFEQIKAHYYVVHTDLNPLSIVPKGPDLANWRSEHGRG</sequence>
</entry>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <end position="177"/>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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    <reference evidence="7 9" key="2">
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            <authorList>
                <person name="de Groot N.N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <reference evidence="6" key="3">
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            </authorList>
        </citation>
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    </reference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP43922">
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="77" mass="8710" checksum="E7A7F5E820B3F090" modified="2017-04-12" version="1">MSKSLTAHDLRGLSRDQLNAKVVELKEELFGLRFQAATGQLESSSRLRNVRKDIARIYTVLQERNLGIVDEPAAQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCU6</accession>
    <name>A0A1Q2CCU6_9ACTN</name>
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        <recommendedName>
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    </protein>
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        <name evidence="8" type="ORF">SAMN05428934_101237</name>
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="8 10" key="2">
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                <person name="de Groot N.N."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 10">RP1</strain>
        </source>
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    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
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    </reference>
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    <comment type="similarity">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY29432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03180"/>
    <dbReference type="EnsemblBacteria" id="AQP43942">
        <property type="protein sequence ID" value="AQP43942"/>
        <property type="gene ID" value="RPIT_03180"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29432">
        <property type="protein sequence ID" value="SDY29432"/>
        <property type="gene ID" value="SAMN05428934_101237"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03180"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01658">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01371_B">
        <property type="entry name" value="Ribosomal_L30_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="L30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005996">
        <property type="entry name" value="Ribosomal_L30_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016082">
        <property type="entry name" value="Ribosomal_L30_ferredoxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15892">
        <property type="entry name" value="PTHR15892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00327">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002211">
        <property type="entry name" value="Ribosomal_L30_bac-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="SSF55129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01308">
        <property type="entry name" value="rpmD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L30" evidence="6">
        <location>
            <begin position="4"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY29432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="60" mass="6500" checksum="8BC8343CDCF7EF9F" modified="2017-04-12" version="1">MADLKITQAKSGVGGKQNQKDTLRTLGLKRIGASVVRQDTPEVRGMIRAVAHLVTVEEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCW9</accession>
    <name>A0A1Q2CCW9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Putative multiple sugar transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_02925</name>
        <name evidence="8" type="ORF">SAMN05428934_101186</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY27808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02925"/>
    <dbReference type="EnsemblBacteria" id="AQP43895">
        <property type="protein sequence ID" value="AQP43895"/>
        <property type="gene ID" value="RPIT_02925"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY27808">
        <property type="protein sequence ID" value="SDY27808"/>
        <property type="gene ID" value="SAMN05428934_101186"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02925"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY27808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="392" mass="41073" checksum="861A0893359084DC" modified="2017-04-12" version="1">MASVKNMLGAVNLRQSGIFLALVAIVILFQIWTGGLLLSPPNVTNLVLQYSYILVLAIGMLFVIVVGHIDLSVGSVIALVGAIAATLVIKMGQSWWVAVLAGLGVGLLIGIWHGFWVAYVGIPGFIVTLASMLLFRGATFMVLGSISLSPMSEEYKQIATGFINGLFGKIGDADIFTLLVGALAVAGFIVGALRTRAARVRYEQPVESMTVMLLKFVAVAAAVMFFAYQLSVSRGMPIVLFILGALVIIYAFVAQNTVYGRHTYAIGGNIHAARLSGVNVKRTIMLVYVNMGLLSAIAGIIYSSRANGAQPAAGNAVELDAIAACFIGGAAVTGGVGRVVGAIIGGTIMAVMTNGMQLLGIDTPTQQIVKGLVLLLAVAFDLVNKRRAVSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD18</accession>
    <name>A0A1Q2CD18_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Methionine aminopeptidase</fullName>
            <shortName evidence="2">MAP</shortName>
            <shortName evidence="2">MetAP</shortName>
            <ecNumber evidence="2 3">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">map</name>
        <name evidence="6" type="ORF">RPIT_03200</name>
        <name evidence="7" type="ORF">SAMN05428934_101241</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2 3">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="2 3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03200"/>
    <dbReference type="EnsemblBacteria" id="AQP43945">
        <property type="protein sequence ID" value="AQP43945"/>
        <property type="gene ID" value="RPIT_03200"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29548">
        <property type="protein sequence ID" value="SDY29548"/>
        <property type="gene ID" value="SAMN05428934_101241"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03200"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070084">
        <property type="term" value="P:protein initiator methionine removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 6" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544433" description="Methionine aminopeptidase" evidence="4">
        <location>
            <begin position="33"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24" evidence="5">
        <location>
            <begin position="13"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY29548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="272" mass="29248" checksum="7A1F7D75711D811C" modified="2017-04-12" version="1">MNIEVKTPDQLRLMRRAGLVVAEGLAAMTAAAAPGITTAELDAIGRDVLAGHGADSSFLNYGADYGTGFPGVACISVNDELVHGIPGERVLAEGDIVSIDFGAIVEGWHGDAARTVAVGRISDEDSRLIDATREAMWAGARAMRDGGRVGDVSRAIETYVKRLPERYGTLREYTGHGIGSEMHMEPDVPNWYRMRPTPRLSVGMALAIEPMLTTGSNQTLELDDEWTVVSRDGSRGSHWENTVAITERGLWVLTEPDGGEERLGDLFGPLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD48</accession>
    <name>A0A1Q2CD48_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_03665</name>
        <name evidence="2" type="ORF">SAMN05428934_101335</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY32390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44021">
        <property type="protein sequence ID" value="AQP44021"/>
        <property type="gene ID" value="RPIT_03665"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY32390">
        <property type="protein sequence ID" value="SDY32390"/>
        <property type="gene ID" value="SAMN05428934_101335"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03665"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY32390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="309" mass="35797" checksum="58D1F69DB1B0DD23" modified="2017-04-12" version="1">MQFLIPVPDNKYYLWQMLVQIAHFREIGYEEDVHYLVAYNDPPSIHLRDFFESEDLKCYIHAYPDTREDRSYSASMKPWLLGQFYGQFPEAEGMVFNYLDPDVMFTGPMDFSPYEAHDGCWYGSDTRSYTGAQYIREKGEQLFLDLCDIAGADPGDVLAHDHNSIGAQYFIKDAGADFWSDVEKASVRAFKHMVETADRYHPEGHQYPIQAWCAEMYMQQFITVRAGFTPIASPELDFHWANHDVAAWDSKPYFHNAGQVTEDGTHFCKISWVESPFNKEITVSPQSASSKYVDLIRRTEAMFPTLVWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD95</accession>
    <name>A0A1Q2CD95_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DivIVA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04060</name>
        <name evidence="3" type="ORF">SAMN05428934_101415</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY34523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04060"/>
    <dbReference type="EnsemblBacteria" id="AQP44088">
        <property type="protein sequence ID" value="AQP44088"/>
        <property type="gene ID" value="RPIT_04060"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY34523">
        <property type="protein sequence ID" value="SDY34523"/>
        <property type="gene ID" value="SAMN05428934_101415"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04060"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019933">
        <property type="entry name" value="DivIVA_domain"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03544">
        <property type="entry name" value="DivI1A_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY34523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="312" mass="35135" checksum="82FCF9A5696D19BA" modified="2017-04-12" version="1">MSLTLDEVRAIRFRMARRGETGYSVGDVDTFIDKVELTFAEHEQERDRLRREVESVQQGGGDAGDGSEHQAELSEKDREIEALRAQIERLSSSESGDDEAFAPQVDDQRVRELEAENERLRAQLEQVRAEFDRSRSEKVTAVGGTEHLTVTTSEEAAPAVTRLLQMATDQATTLVNEAQTEAQRKIEEAEARANEIKTDARTKAERVESEARVNAEAMTNDATARATDLDRQTEERRRELFAELEHEQGVLTGKVDALRSFERSYRENITGSLQRLLAAVKEDQPEPHDVPELAQRHSDTPRLDALAEGDQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDC0</accession>
    <name>A0A1Q2CDC0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase-binding protein RbpA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rbpA</name>
        <name evidence="4" type="ORF">RPIT_04255</name>
        <name evidence="5" type="ORF">SAMN05428934_101455</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Bind 1 Zn(2+) per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Forms a complex with the RNAP catalytic core and with free principal sigma factors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNA polymerase-binding protein RbpA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY35770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04255"/>
    <dbReference type="EnsemblBacteria" id="AQP44122">
        <property type="protein sequence ID" value="AQP44122"/>
        <property type="gene ID" value="RPIT_04255"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY35770">
        <property type="protein sequence ID" value="SDY35770"/>
        <property type="gene ID" value="SAMN05428934_101455"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04255"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001000">
        <property type="term" value="F:bacterial-type RNA polymerase core enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01483">
        <property type="entry name" value="RbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038638">
        <property type="entry name" value="RbpA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025182">
        <property type="entry name" value="RNApol-bd_RbpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018527">
        <property type="entry name" value="Rubredoxin_Fe_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13397">
        <property type="entry name" value="RbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00202">
        <property type="entry name" value="RUBREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY35770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="118" mass="12676" checksum="1212FC71403BD061" modified="2017-04-12" version="1">MAGGNAIRGSRVGAGPMGEAERGDSAPRTRVSYFCAGGHVTRPAFAVDAPIPESWDCPRCGLPANTDEENPPPPPKITPYKTHLAYVKERRTDAEAEQILEEAVTALRARRASGEVIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDK1</accession>
    <name>A0A1Q2CDK1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">30S ribosomal protein S15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsO</name>
        <name evidence="8" type="ORF">RPIT_04630</name>
        <name evidence="9" type="ORF">SAMN05428934_101532</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="3 6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04630"/>
    <dbReference type="EnsemblBacteria" id="AQP44189">
        <property type="protein sequence ID" value="AQP44189"/>
        <property type="gene ID" value="RPIT_04630"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37679">
        <property type="protein sequence ID" value="SDY37679"/>
        <property type="gene ID" value="SAMN05428934_101532"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04630"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_B">
        <property type="entry name" value="Ribosomal_S15_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_S15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005290">
        <property type="entry name" value="Ribosomal_S15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="S15_NS1_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321">
        <property type="entry name" value="PTHR23321"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="SSF47060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00952">
        <property type="entry name" value="S15_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY37679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="87" mass="10139" checksum="8BE48C5341D21EC3" modified="2017-04-12" version="1">MDAELKKKTIEEYATQPGDTGSPDVQIALLTKRIAHLTEHLKEHKGDHHSRRGLMLMVGQRRRLLNYVAKQDVEHYRELIARLGLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDP0</accession>
    <name>A0A1Q2CDP0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Heme chaperone HemW</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_04880</name>
        <name evidence="12" type="ORF">SAMN05428934_101584</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY38972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04880"/>
    <dbReference type="EnsemblBacteria" id="AQP44229">
        <property type="protein sequence ID" value="AQP44229"/>
        <property type="gene ID" value="RPIT_04880"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY38972">
        <property type="protein sequence ID" value="SDY38972"/>
        <property type="gene ID" value="SAMN05428934_101584"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04880"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004559">
        <property type="entry name" value="HemW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00562">
        <property type="entry name" value="HemN-like__clustered_with_heat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00539">
        <property type="entry name" value="hemN_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="10">
        <location>
            <begin position="21"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY38972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="396" mass="43058" checksum="2CDC71E4DF5C0868" modified="2017-04-12" version="1">MPQLPDGDPAPRDGSLPAHALDASRPLSLYIHVPFCRTRCGYCDFNTYTPSEVGELAPDTYLGAALAELDLAARVLGPRRVDTVFFGGGTPTMLPADQLVGLLSAARDRFDVAPDAEITTEGNPETLTPRYLATLRAGGFTRLSLGLQSVVGHVLKVLERTHTPRRGLDAARWASQEGFDHISLDLIYGTPGESMDDWRDSLDAVTATPVDHVSAYSLIVEEGTRLAVQVKRGLIAMPDDDDLADKYLVADEKLSSLGYANYEVSNWARPGGRCLHNLAYWRGADWWGIGPGAHSHIGGVRFWNRKHPRSYAAALAEGGSPALAREVLSDDDRRIERVLLELRLAEGVALDVLTDTERSRLPDLERRGLATTSGTSLTLTQAGRLLADGVIRDLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDP2</accession>
    <name>A0A1Q2CDP2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fructose-1,6-bisphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_04955</name>
        <name evidence="4" type="ORF">SAMN05428934_101597</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY39312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04955"/>
    <dbReference type="EnsemblBacteria" id="AQP44242">
        <property type="protein sequence ID" value="AQP44242"/>
        <property type="gene ID" value="RPIT_04955"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY39312">
        <property type="protein sequence ID" value="SDY39312"/>
        <property type="gene ID" value="SAMN05428934_101597"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04955"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY39312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="258" mass="28509" checksum="39B67E0EB7404C8D" modified="2017-04-12" version="1">METDAIMDLLRRTADEVIRPRFRALTDADIEEKARPGDLVTVADREAETFLTALLQERHPDAVVVGEEGVFLNTATLAGLHNADHAFIIDPIDGTGNFARGDERYGVMLAETRGGITTRGWIWQPEFDRGYAVERGNGVELNGSPIERPRHNRPPLGAAGRKKLVGFDADGQLSPAVRTQFACAFDYPSILHGDTDFVFYTSLNPWDHLAGSLMVVEQGGVSRTLDGMAYNLLNRSRGLLVANDTLSWMAAQQYWPTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDS1</accession>
    <name>A0A1Q2CDS1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">4-hydroxybenzoyl-CoA thioesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_05045</name>
        <name evidence="6" type="ORF">SAMN05428934_101615</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl coenzyme A hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY39783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05045"/>
    <dbReference type="EnsemblBacteria" id="AQP44258">
        <property type="protein sequence ID" value="AQP44258"/>
        <property type="gene ID" value="RPIT_05045"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY39783">
        <property type="protein sequence ID" value="SDY39783"/>
        <property type="gene ID" value="SAMN05428934_101615"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05045"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016790">
        <property type="term" value="F:thiolester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040170">
        <property type="entry name" value="Cytosol_ACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033120">
        <property type="entry name" value="HOTDOG_ACOT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11049">
        <property type="entry name" value="PTHR11049"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51770">
        <property type="entry name" value="HOTDOG_ACOT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HotDog ACOT-type" evidence="4">
        <location>
            <begin position="4"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="HotDog ACOT-type" evidence="4">
        <location>
            <begin position="162"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY39783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="319" mass="35360" checksum="7BFC4D878FF1B355" modified="2017-04-12" version="1">MPGTQRGVTLRFLAEPMDANVRGFVDGGKVLEWIDKAGYAAAVGWAGTYAVTGYVGNIHFIHPVRSTDLVVVQARIVYTGRTSMQIVCTVSSGDPRSDESTLNTQCILQFVAMEDGKPVAVPSFEPRDDWEREQHDRAVELNGARRAIEEAMAEQTFEGESEACRETLRFLADPTDVNWGGKVHGGYVMAWIDNAAQIVAERWGGGPAALVFAGGVRFYRPMFIGDLVEVEARLLLTGTTSMHINVTVRSGDPRTRQLRETTHCTMVFCGIDDKGRKRPVPDWEPRLPLDVALQDHARQMIAIRDRLLRPLPKELPADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDS5</accession>
    <name>A0A1Q2CDS5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 9">Uroporphyrinogen decarboxylase</fullName>
            <shortName evidence="8">UPD</shortName>
            <shortName evidence="8">URO-D</shortName>
            <ecNumber evidence="4 8 9">4.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hemE</name>
        <name evidence="13" type="ORF">RPIT_04720</name>
        <name evidence="14" type="ORF">SAMN05428934_101553</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>4 H(+) + uroporphyrinogen III = 4 CO2 + coproporphyrinogen III</text>
            <dbReference type="Rhea" id="RHEA:19865"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="4.1.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8 9">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 10">Belongs to the uroporphyrinogen decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.37" evidence="4 8 9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY38195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04720"/>
    <dbReference type="EnsemblBacteria" id="AQP44205">
        <property type="protein sequence ID" value="AQP44205"/>
        <property type="gene ID" value="RPIT_04720"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY38195">
        <property type="protein sequence ID" value="SDY38195"/>
        <property type="gene ID" value="SAMN05428934_101553"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04720"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00321"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004853">
        <property type="term" value="F:uroporphyrinogen decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00717">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00218">
        <property type="entry name" value="URO_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006361">
        <property type="entry name" value="Uroporphyrinogen_deCO2ase_HemE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000257">
        <property type="entry name" value="Uroporphyrinogen_deCOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01208">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="SSF51726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01464">
        <property type="entry name" value="hemE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00906">
        <property type="entry name" value="UROD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00907">
        <property type="entry name" value="UROD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8 9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 8 9" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uroporphyrinogen_deCOase" evidence="11">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="Uroporphyrinogen_deCOase" evidence="12">
        <location>
            <begin position="135"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="22"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS00907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP44205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY38195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="335" mass="35766" checksum="4641A45C6DDF821B" modified="2017-04-12" version="1">MSALLTALSGQRPEKLPVWFMRQAGRSLPEYKKVREGTTILEACLKPELAAEITLQPVRRHGVDAAIFFSDIMMPLVLAGVGVEIHSGVGPVIDEPIRTAEDVDALVGREMADPSAISEAVRLVVDELGDETPLIGFAGAPFTLAAYLVEGKGSRDHLAARTMMHADPHSWQRLLAWCAELSGEFLRVQVDAGARAVQLFDSWAGALTRADYVERVAPHSAAALAAVEGLVPRIHFGTGTRHILDDMAACGVEAMGIDYRTPLDEAAWLLPGLPLQGNIDPALLAAGWDALERHALDVVERGKAAPAHIVNLGHGVPPTTDPGVLTDLVALLHAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDT6</accession>
    <name>A0A1Q2CDT6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-oxoacyl-[acyl-carrier-protein] synthase 3</fullName>
            <ecNumber evidence="7">2.3.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">3-oxoacyl-[acyl-carrier-protein] synthase III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Beta-ketoacyl-ACP synthase III</fullName>
            <shortName evidence="7">KAS III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">fabH</name>
        <name evidence="10" type="ORF">RPIT_05205</name>
        <name evidence="11" type="ORF">SAMN05428934_101647</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>acetyl-CoA + H(+) + malonyl-[ACP] = 3-oxobutanoyl-[ACP] + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9625"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78450"/>
            <dbReference type="EC" id="2.3.1.180"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the thiolase-like superfamily. FabH family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.180" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY40621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05205"/>
    <dbReference type="EnsemblBacteria" id="AQP44284">
        <property type="protein sequence ID" value="AQP44284"/>
        <property type="gene ID" value="RPIT_05205"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY40621">
        <property type="protein sequence ID" value="SDY40621"/>
        <property type="gene ID" value="SAMN05428934_101647"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05205"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033818">
        <property type="term" value="F:beta-ketoacyl-acyl-carrier-protein synthase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01815">
        <property type="entry name" value="FabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004655">
        <property type="entry name" value="FabH_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00747">
        <property type="entry name" value="fabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="9">
        <location>
            <begin position="115"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="8">
        <location>
            <begin position="238"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="ACP-binding" evidence="7">
        <location>
            <begin position="255"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY40621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="329" mass="34793" checksum="41A21AA7EC49CC30" modified="2017-04-12" version="1">MTLKTSTGATHARLMSVGGARGSRVVTNDELCTMIDSTDEWITQRTGIKERRWAADGEDAETLGLEAASKAIERAGLQPSDIDAVLVSTVSHFMQTPALACIIAEKLGLPAPAAFDLSAACAGFCYGVGLAESMVRSGSARHVLVLGVEVLSRYTDIDDRSTAFLFSDGAGAVVIGPSDEPAIGPTIWGSKPEAHAVIEIDDWRTVGPEEKGPFIHMEGREVFKWATTSIVEKAKETLEASGLTPDELDCFIPHQANNRITDSMLRHLKLPEEVVVARDIVTMGNSSAASIPLAMESLLESGQAKSGDSALIIGFGAGLVFAGQTVILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDT8</accession>
    <name>A0A1Q2CDT8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid/polyamine/organocation transporter, APC superfamily</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_05005</name>
        <name evidence="7" type="ORF">SAMN05428934_101607</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY39577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05005"/>
    <dbReference type="EnsemblBacteria" id="AQP44251">
        <property type="protein sequence ID" value="AQP44251"/>
        <property type="gene ID" value="RPIT_05005"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY39577">
        <property type="protein sequence ID" value="SDY39577"/>
        <property type="gene ID" value="SAMN05428934_101607"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05005"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="220"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="263"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="368"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY39577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="412" mass="42958" checksum="6D6E83CA9697936D" modified="2017-04-12" version="1">MARSELSRSLGLWDAVAIGVASMVGAGVFAVWGPAAQSAGSWLLLGLVIASTVAWANATSSAQLAAQYPAAGGTYVYGRERLGEWPGYLAGWSFVIGKTASCAAMALAFAAYVAPEGWQKPVAISVVWVLVGVNSLGVTRTAQAAKVLVTLSLTGIVLAVAFGWFAGPEVGRFAWAQPVGGAYGVLQSAGLLFFAFAGYARIATLGEEVRDPAQTIRRAIVGALTFVLALYAVVGVSLLALLGPEVLASQTAPLLLLVEGNPVLRIILTVGAGAAIAGALLGLLSGIGRTWLAMARERDLPGWFDHTHPVTKVPHRIEVTLGVLLTVILLLVDLRGAIGFSSFGVLLYYFVANVAAHSQDAAHRRYPKAWQVLGAALCFVLVVTLPWQSVLGGLLVLGLGVAWRALRPAALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDU6</accession>
    <name>A0A1Q2CDU6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Fur family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="133" mass="14715" checksum="107BB40103C41D18" modified="2017-04-12" version="1">MTSTKPPTRHTWQRAAIRDLLENAHEFRTAQQIHDQLRELGAKVGLATVYRALQAMADADEVDVLRTPEGEAAYRKCSKGHHHHLVCRACGYSIEIAAREIEEWAAGVAAKNGFTDVGHELEVFGVCQSCSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDW7</accession>
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        <name evidence="2" type="ORF">SAMN05428934_1034</name>
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    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
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            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05285"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY65099">
        <property type="protein sequence ID" value="SDY65099"/>
        <property type="gene ID" value="SAMN05428934_1034"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016884">
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019004">
        <property type="entry name" value="YqeY/Aim41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042184">
        <property type="entry name" value="YqeY/Aim41_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28055">
        <property type="entry name" value="PTHR28055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09424">
        <property type="entry name" value="YqeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="SSF89095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY65099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="151" mass="16021" checksum="70553B83984C6EFA" modified="2017-04-12" version="1">MGATKRRLKQDLAAALRAKDETAKTNIRMMMGAITVEEVAGDSARELSDAEELAVITREMRKRREASAIYAEAGRAELAEKEAAEADFLAAYLPAPLTEDELAALVDEAVADLGHAPTMKDMGALVKAVGARADGRAEGKQIAALVRAKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDX3</accession>
    <name>A0A1Q2CDX3_9ACTN</name>
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            <fullName evidence="3">Uncharacterized conserved protein, Tic20 family</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">RPIT_05315</name>
        <name evidence="3" type="ORF">SAMN05428934_10310</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
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    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05315"/>
    <dbReference type="EnsemblBacteria" id="AQP44303">
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        <property type="gene ID" value="RPIT_05315"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY65281">
        <property type="protein sequence ID" value="SDY65281"/>
        <property type="gene ID" value="SAMN05428934_10310"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05315"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012551">
        <property type="entry name" value="DUF1707"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08044">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY65281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="191" mass="20580" checksum="412BD92887E97656" modified="2017-04-12" version="1">MNNFLVNDQQRDRAVDHLQACYANGSLDEAEFDRRLDAALNARDRAELNRSLQGLARIAPPAPLTPPLRRPGQPTSGENLGAGLAHLSGLFTWVIGPAIAKAVATPGSRIWWEASRALSFQLTAALVGIASLGVAVVLGFDGLLLLGWMGWFFGTIIASLRAFNGKSGTGQFDRFLVMREQPQVGALARTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDY2</accession>
    <name>A0A1Q2CDY2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_05395</name>
        <name evidence="2" type="ORF">SAMN05428934_10326</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
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    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY65738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05395"/>
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        <property type="gene ID" value="RPIT_05395"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY65738">
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        <property type="gene ID" value="SAMN05428934_10326"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05395"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019639">
        <property type="entry name" value="DUF2505"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10698">
        <property type="entry name" value="DUF2505"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY65738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="156" mass="17435" checksum="94BB6CD0D68EF79B" modified="2017-04-12" version="1">MKLDYKQTYPAEPARVVELLRNEDFISDVARHAGATEHRVEVRADATLLSMRMPVPEKLTKFVGETIQLNQTFRFTDPGPDGVAHGTVDVDVPGMPVDVDARGVLRPEGDRTIGHYTGDVKVKIPLIGKKVEAQVEPFIREAFDGIERRAADWLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE26</accession>
    <name>A0A1Q2CE26_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_05780</name>
        <name evidence="2" type="ORF">SAMN05428934_103103</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44382">
        <property type="protein sequence ID" value="AQP44382"/>
        <property type="gene ID" value="RPIT_05780"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67775">
        <property type="protein sequence ID" value="SDY67775"/>
        <property type="gene ID" value="SAMN05428934_103103"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05780"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY67775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="84" mass="9339" checksum="3C7682F5C18D8A4E" modified="2017-04-12" version="1">MALRTNLPCMARSQWSANPLGFAGAWTGADGARWRTECDTPATGANACRSYRLTTVYSAEPRPTGGYDFAQDNQWVFNNIVMFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE36</accession>
    <name>A0A1Q2CE36_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carbohydrate ABC transporter substrate-binding protein, CUT1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_05835</name>
        <name evidence="2" type="ORF">SAMN05428934_103114</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05835"/>
    <dbReference type="EnsemblBacteria" id="AQP44392">
        <property type="protein sequence ID" value="AQP44392"/>
        <property type="gene ID" value="RPIT_05835"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68060">
        <property type="protein sequence ID" value="SDY68060"/>
        <property type="gene ID" value="SAMN05428934_103114"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05835"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY68060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="426" mass="45997" checksum="F23D2DE7A0ECBB25" modified="2017-04-12" version="1">MRRRTLLTGFGGIAATGALSACGGGETQQNEAPAEIGEDTEATLELAYWDRNQSVTVEALIASFTEKYPRITVTPALTGPSEYWTRLRTQAEGNNLPDVFWMSGLHVQLYASNGMLAPVADDVNFDVFPQAMTDLYTVDGVRYGIPKDFDTIACWVNQRLVEEAGVSLPDPETWTWEEFGETTRAIAAGLGDRGHAVVTDLNIGGQQNWYNTVAQAGGYIIRDGRSGYGDPDTIRGLEFWSNLVADGVVPHPRVIADNPPQTVFNSGRAAIHHTGSWETAGLLADYPDPGELVVVPLPRDKERASTIHGLAYVVAANSPNLAAAAALQRHLTSEEAGRTDAANGTAIPAWEGTADTWHEVKPEWNLEVFTTAAEEYAVPYPVSRNTAAWNQLEADILTPAFAGEVPMAQAAEQLAEQMDALLAAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE41</accession>
    <name>A0A1Q2CE41_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized membrane protein YeiH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_05665</name>
        <name evidence="10" type="ORF">SAMN05428934_10380</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0126 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05665"/>
    <dbReference type="EnsemblBacteria" id="AQP44361">
        <property type="protein sequence ID" value="AQP44361"/>
        <property type="gene ID" value="RPIT_05665"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67126">
        <property type="protein sequence ID" value="SDY67126"/>
        <property type="gene ID" value="SAMN05428934_10380"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05665"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005115">
        <property type="entry name" value="Gly_transporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03458">
        <property type="entry name" value="Gly_transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="12"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="98"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY67126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="239" mass="25765" checksum="B225959FCF8C607F" modified="2017-04-12" version="1">MSCGRESDVLTILWAIGITAEAVTGALAAGRERMDLFGVTMVAFVAALGGGSLRDVLLGHYPLVWVRDPQYVLLVMAAAILTVSVAGLMNYFRQLFLVLDALGLVVFSILGARVALEMGHGVTIAVVAAVLTGVAGGILRDLLCDRVPLVLREELYASVSVLSALLFVALLRFGVQENAAVVATLVTGFVLRLLALRFRWRLPVFAYEEVRVNGAEALRARLSSFRALRLLRSRPVVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE52</accession>
    <name>A0A1Q2CE52_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pyrophosphate--fructose 6-phosphate 1-phosphotransferase</fullName>
            <ecNumber evidence="8">2.7.1.90</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">6-phosphofructokinase, pyrophosphate dependent</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">PPi-dependent phosphofructokinase</fullName>
            <shortName evidence="8">PPi-PFK</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Pyrophosphate-dependent 6-phosphofructose-1-kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pfp</name>
        <name evidence="10" type="ORF">RPIT_05755</name>
        <name evidence="11" type="ORF">SAMN05428934_10398</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6-bisphosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13613"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="2.7.1.90"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="8">Non-allosteric.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer or homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'P' sub-subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.90" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05755"/>
    <dbReference type="EnsemblBacteria" id="AQP44377">
        <property type="protein sequence ID" value="AQP44377"/>
        <property type="gene ID" value="RPIT_05755"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67631">
        <property type="protein sequence ID" value="SDY67631"/>
        <property type="gene ID" value="SAMN05428934_10398"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05755"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047334">
        <property type="term" value="F:diphosphate-fructose-6-phosphate 1-phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01977">
        <property type="entry name" value="Phosphofructokinase_II_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011405">
        <property type="entry name" value="PPi-PFK_SMc01852"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036484">
        <property type="entry name" value="PPi-PFK_SMc01852"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="SSF53784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 8 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFK" evidence="9">
        <location>
            <begin position="4"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="149"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="194"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="323"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP" evidence="8">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi" evidence="8">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY67631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="406" mass="43733" checksum="E7EE2240E3CB19BA" modified="2017-04-12" version="1">MVKKVAILTAGGFAPCLSSAIGGLIERYTQVAPDVEIIAYRHGYQGLLKGDFLVVDETVRANAALLHKFGGSPVGNSRVKLTNAKDLVKRGLVNEGDNPLQVAADRLVADGVDVLHTIGGDDTNTTAADLAAYLAEHDYGLTVVGLPKTIDNDVIPIRQSLGAWTAAEQGAIFAQNIVAEHNSGSRMLIVHEVMGRHCGWLTAATAQKYREWLDTQEWLPEIGLSREAWDIHGVYVPEGVIDIAKEAERLHTIMDEVGNVTIFLSEGAGLDSIVAEMEAAGEEVPRDPFGHVKLDKVNPGAWFADKFAAKLDAEKVMIQKSGYFSRSAAANDADLALIKQCTDLAVDCALRGEPGVIGHDEENGDVLTAIAFDRIKGGKPFDINQQWYKDMLEAIGQEFPAAAEAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE99</accession>
    <name>A0A1Q2CE99_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Orotidine 5'-phosphate decarboxylase</fullName>
            <ecNumber evidence="3">4.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">OMP decarboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_06170</name>
        <name evidence="9" type="ORF">SAMN05428934_103179</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + orotidine 5'-phosphate = CO2 + UMP</text>
            <dbReference type="Rhea" id="RHEA:11596"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="4.1.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.23" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY69681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06170"/>
    <dbReference type="EnsemblBacteria" id="AQP44449">
        <property type="protein sequence ID" value="AQP44449"/>
        <property type="gene ID" value="RPIT_06170"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY69681">
        <property type="protein sequence ID" value="SDY69681"/>
        <property type="gene ID" value="SAMN05428934_103179"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06170"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004590">
        <property type="term" value="F:orotidine-5'-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011995">
        <property type="entry name" value="OMPdecase_type-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43375">
        <property type="entry name" value="PTHR43375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02127">
        <property type="entry name" value="pyrF_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OMPdecase" evidence="7">
        <location>
            <begin position="17"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY69681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="270" mass="27278" checksum="36B50AFBEC821FCF" modified="2017-04-12" version="1">MSTYAERLNAVTSKRGRLCVGIDPMPSVVEAWGLPNSVAGLEACARGIVEELGGLVAVFKPQSAFFEAFGSRGVAVLERVLADIRQAGALSILDVKRGDIGSSMAGYASAFLGDDAPLRADAITVSPYLGVGALRPAIDAAVAGGQGLYVLARTSNPEGAPIQLATSGSATVAQHVVDEAARINLRADRAVGLVVGGTHSDVGCSLESFNASILVPGIGAQGGSIAGLADVFGPALAHVLPTASRDVIGAGAAELSSRAHRLLDEARVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEA8</accession>
    <name>A0A1Q2CEA8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="10">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="10">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">alaS</name>
        <name evidence="12" type="ORF">RPIT_06235</name>
        <name evidence="13" type="ORF">SAMN05428934_103192</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="10"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06235"/>
    <dbReference type="EnsemblBacteria" id="AQP44459">
        <property type="protein sequence ID" value="AQP44459"/>
        <property type="gene ID" value="RPIT_06235"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70043">
        <property type="protein sequence ID" value="SDY70043"/>
        <property type="gene ID" value="SAMN05428934_103192"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06235"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
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        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
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        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
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        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF101353"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 10" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II_ALA" evidence="11">
        <location>
            <begin position="1"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="569"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="573"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="672"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="676"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
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        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00036"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP44459.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY70043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="883" mass="94117" checksum="E06C1CFA143E0733" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEE8</accession>
    <name>A0A1Q2CEE8_9ACTN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_06345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06345"/>
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    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06345"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="200" mass="22218" checksum="1E75CCB7EAD54CD3" modified="2017-04-12" version="1">MRTIVRLRLDIEIVGADALNGLDQPVVLAANEQGALDYQLLRRILPARLRPTTARPSRALARGRNVVVFADEPGQGRLVGEFSTIPAELANQHNVAIVPVGIAGTFKLKRILKLALRTKPKVSVRFGAPIYLRGRSIGDATAELQSRVEQLVHEGELSWWTIERRRSGSQAPSPLDTAARWRRLWDQSAPSADPSPRIWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEH0</accession>
    <name>A0A1Q2CEH0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Potassium transporter Kef</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="RPIT_06295"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06295"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="1">
        <location>
            <begin position="138"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="359" mass="38568" checksum="8B3C7174CC3F1855" modified="2017-04-12" version="1">MAKMQPGGRGGAVSLVSLPRIEISPFKELARRAVIALALLGLTTLIVWLDRDAYIDNTGQDGVSLIDALYYATVTVTTTGYGDITPIAPHARLLNALIITPLRVSFLVVLVGTTIEVLANQGSRSIKDSMWRKRMRNHVVVIGYGTKGRSAVNTLRRQGTPADKIVVIDTDPNSISDANFDGLAAFQGDATRRDLLRRAEISKAKGVIISLDKDGTSILATLTVRQLNPTAGVVVSVREHENVPLVRQSGASSVVTSSETVGRLLGLSAIGPDLGAIMQDMLTGGEGLEVHQRQAEPHEAGQPPSAVQGERVIGLIRNGTLRRFYDQTASRIELGDELIVVRRAQAPTSKDLLRFAAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEI0</accession>
    <name>A0A1Q2CEI0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">HAD-superfamily subfamily IB hydrolase, TIGR01490</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Haloacid dehalogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_06355</name>
        <name evidence="7" type="ORF">SAMN05428934_103216</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the HAD-like hydrolase superfamily. SerB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the fatty acyl-CoA reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06355"/>
    <dbReference type="EnsemblBacteria" id="AQP44480">
        <property type="protein sequence ID" value="AQP44480"/>
        <property type="gene ID" value="RPIT_06355"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70689">
        <property type="protein sequence ID" value="SDY70689"/>
        <property type="gene ID" value="SAMN05428934_103216"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06355"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080019">
        <property type="term" value="F:fatty-acyl-CoA reductase (alcohol-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09071">
        <property type="entry name" value="FAR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026055">
        <property type="entry name" value="FAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033640">
        <property type="entry name" value="FAR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="Far_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006385">
        <property type="entry name" value="HAD_hydro_SerB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11011">
        <property type="entry name" value="PTHR11011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01490">
        <property type="entry name" value="HAD-SF-IB-hyp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_binding_4" evidence="5">
        <location>
            <begin position="39"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY70689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="782" mass="85933" checksum="CEDAFDC31340C583" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEJ3</accession>
    <name>A0A1Q2CEJ3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DivIVA protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06610</name>
        <name evidence="3" type="ORF">SAMN05428934_103268</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY72106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06610"/>
    <dbReference type="EnsemblBacteria" id="AQP44523">
        <property type="protein sequence ID" value="AQP44523"/>
        <property type="gene ID" value="RPIT_06610"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY72106">
        <property type="protein sequence ID" value="SDY72106"/>
        <property type="gene ID" value="SAMN05428934_103268"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR007793">
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    <dbReference type="Pfam" id="PF05103">
        <property type="entry name" value="DivIVA"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="212"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="299"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY72106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="355" mass="38707" checksum="6E10AF31052F5035" modified="2017-04-12" version="1">MTDEHTENTELTGLNLFNDKASAAGSFPHAMLGYDKLSVDSYVRELESELASLRAEVRQQTREVQYVRQEVGTTDFTRLGAHATGLLRAAEAQAVDIVDRAEHEAERIKTEARRTASVLRESAQQEADDVRITGLAGLRQLRQEQGEAGKAALEKARRDADLIVGDARSRAGAIVGAAEAKAESILESARSESNRRLAEAERSAAEIVLSARQDAEKSLQTVTEAAEKAQKAIDDRLAQAERDAEAASVRAAEARVEADKIRAAAVKDAEDLRLAATRQSEETLTTMRNRAKDAEAALEEQLAWRREQLQREIATLESRRSSALAQLSNLRALAEESDAQFADEATTVIGSDGDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEK3</accession>
    <name>A0A1Q2CEK3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pimeloyl-ACP methyl ester carboxylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06630</name>
        <name evidence="3" type="ORF">SAMN05428934_103272</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY72225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06630"/>
    <dbReference type="EnsemblBacteria" id="AQP44527">
        <property type="protein sequence ID" value="AQP44527"/>
        <property type="gene ID" value="RPIT_06630"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY72225">
        <property type="protein sequence ID" value="SDY72225"/>
        <property type="gene ID" value="SAMN05428934_103272"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06630"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="15"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY72225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="257" mass="28544" checksum="4273349FB09E447D" modified="2017-04-12" version="1">MKLHEKVIGSGPTHVVFLHGLFGQGKNFGGIANDISDIATSHLVDLPNHGRSPWTETFSLDNQADAVADWIADAFDAPVALVGHSLGGKLGMRIALRRGELLDRLMVVDISPARNVSAAEFVNLVAALRQLNLDEVTSRSYADEALTELIPTDRIRRFLLQNLRHKGDSWSWLPNLDLLGDHLHDVGGWPRIEGVYDGPVLWVNGGRSPYVQPEHLAPMRELFPRVLQLTLKNASHWVHSDDPDAFVTVVRHFLTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEP0</accession>
    <name>A0A1Q2CEP0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">Dihydroxy-acid dehydratase</fullName>
            <shortName evidence="15">DAD</shortName>
            <ecNumber evidence="14 15">4.2.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ilvD</name>
        <name evidence="16" type="ORF">RPIT_07000</name>
        <name evidence="17" type="ORF">SAMN05428934_11045</name>
    </gene>
    <organism evidence="16 18">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 18" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1T</strain>
        </source>
    </reference>
    <reference evidence="17 19" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">RP1</strain>
        </source>
    </reference>
    <reference evidence="16" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:24809"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:24810"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate = (S)-3-methyl-2-oxopentanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:27694"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="15">Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13 15">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12 15">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the IlvD/Edd family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.9" evidence="14 15"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07000"/>
    <dbReference type="EnsemblBacteria" id="AQP44592">
        <property type="protein sequence ID" value="AQP44592"/>
        <property type="gene ID" value="RPIT_07000"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08954">
        <property type="protein sequence ID" value="SDZ08954"/>
        <property type="gene ID" value="SAMN05428934_11045"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07000"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00057"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00061"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004160">
        <property type="term" value="F:dihydroxy-acid dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00012">
        <property type="entry name" value="IlvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004404">
        <property type="entry name" value="DihydroxyA_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="SSF143975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00110">
        <property type="entry name" value="ilvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07070"/>
    <dbReference type="EnsemblBacteria" id="AQP44604">
        <property type="protein sequence ID" value="AQP44604"/>
        <property type="gene ID" value="RPIT_07070"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08610">
        <property type="protein sequence ID" value="SDZ08610"/>
        <property type="gene ID" value="SAMN05428934_11030"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07070"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09022">
        <property type="entry name" value="Aldose_epim_Ec_YihR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037480">
        <property type="entry name" value="YihR-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ08610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="292" mass="32085" checksum="EE662E26F7BD9273" modified="2017-04-12" version="1">MTIKPTGEQLEINHGRYAVVVTEVGATLRSLTVDGEEVLWTFPETGTPRHCSGQQLTPWPNRIRDGRYTFDGQQQQLDITEPPRHTALHGLGRFLPWRVESRSATEVVQSAVIYPQNGWDGVLGMTIVHRLSDDGLTVRVTAENLGGNRLPYGYGAHPYVAADLATAVLTTPFRRELLVDEVRLLPGELTEVTVANDFRGGKTVGDTVLDTAFCDPETGWEVSVTTADRTVSLWADDSMRWGQVFTAPTRDGIAIEPMTCGPDAFNEGPTHDGVIILEPGESTSCEWGVRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF09</accession>
    <name>A0A1Q2CF09_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bacteriocin-protection, YdeI or OmpD-Associated</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07430</name>
        <name evidence="2" type="ORF">SAMN05428934_11443</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000014">
        <property type="protein sequence ID" value="SDZ18642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_061615921.1">
        <property type="nucleotide sequence ID" value="NZ_FNPU01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07430"/>
    <dbReference type="EnsemblBacteria" id="AQP44660">
        <property type="protein sequence ID" value="AQP44660"/>
        <property type="gene ID" value="RPIT_07430"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ18642">
        <property type="protein sequence ID" value="SDZ18642"/>
        <property type="gene ID" value="SAMN05428934_11443"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07430"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ18642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="85" mass="9874" checksum="F275A6277EBE3F94" modified="2017-04-12" version="1">MPEDLSDALAEAPLEIREMWADLTPMARWEWVRWVQVTRNPETRRRRVLASISKMNSGKRRPCCFDLSSCTDPDLARSGKLREPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF21</accession>
    <name>A0A1Q2CF21_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2 3">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07390</name>
        <name evidence="3" type="ORF">SAMN05428934_11435</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000014">
        <property type="protein sequence ID" value="SDZ18474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44655">
        <property type="protein sequence ID" value="AQP44655"/>
        <property type="gene ID" value="RPIT_07390"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ18474">
        <property type="protein sequence ID" value="SDZ18474"/>
        <property type="gene ID" value="SAMN05428934_11435"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07390"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ18474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="527" mass="56290" checksum="2AF01672CB7E29B9" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF34</accession>
    <name>A0A1Q2CF34_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_07870</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07870"/>
    <dbReference type="EnsemblBacteria" id="AQP44732">
        <property type="protein sequence ID" value="AQP44732"/>
        <property type="gene ID" value="RPIT_07870"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07870"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="9"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="319" mass="34000" checksum="8231029BE55B4048" modified="2017-04-12" version="1">MAELFAGRYLLLEPIGEGGMGTVWRVEDLKQNRVVAAKILRQSHSTSLLRFVREQSLRIHHPHVLMPLGWAGEDDRVLFTMPIVAGGSLATLVGDYGALPPLFVAEILRQIASALIAVHDGRLVHRDVKPANILLDATGAGRPYAYLTDFGIAVELDGPRFTETGLVTGTPGYLAPELAALGDPAPASDAYSLGSVGLHLLTGVRPQDVPRQGSAPIGVPDALWDTLVALTEPDPQRRLTLPDALARLAAPELAWHDDAAGEVEVFDHFVPEPAAEPGAGAQLAPEPGDAAGRRLSTRDLLVFGFFGLLMILGIVLLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF89</accession>
    <name>A0A1Q2CF89_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">DNA repair protein RecN</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Recombination protein N</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_08090</name>
        <name evidence="11" type="ORF">SAMN05428934_11358</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">May be involved in recombinational repair of damaged DNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the RecN family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ17108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08090"/>
    <dbReference type="EnsemblBacteria" id="AQP44768">
        <property type="protein sequence ID" value="AQP44768"/>
        <property type="gene ID" value="RPIT_08090"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ17108">
        <property type="protein sequence ID" value="SDZ17108"/>
        <property type="gene ID" value="SAMN05428934_11358"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08090"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004604">
        <property type="entry name" value="DNA_recomb/repair_RecN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11059">
        <property type="entry name" value="PTHR11059"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003128">
        <property type="entry name" value="RecN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00634">
        <property type="entry name" value="recN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC_N" evidence="9">
        <location>
            <begin position="1"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="338"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR003128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDZ17108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="560" mass="59018" checksum="E1657D3864A9CE29" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF98</accession>
    <name>A0A1Q2CF98_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">IclR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_07910</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07910"/>
    <dbReference type="EnsemblBacteria" id="AQP44740">
        <property type="protein sequence ID" value="AQP44740"/>
        <property type="gene ID" value="RPIT_07910"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07910"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="7"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="4">
        <location>
            <begin position="67"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="241" mass="25400" checksum="66D03779F3B2AE51" modified="2017-04-12" version="1">MDDSSGVGVLDKAAAVLSALERNPLTLAGLVTATGLARPTAHRLAVALEHHRYVGRDLQGRFVLGPRLIELAESAGEDPLLATAGPILNRLRDITGESVQLFRRQGDTRICVASVERPTGLRDSVQVGAQLSMTAGSAAQVLLAWEEPDKLEKLLESASFTMSTLNTVRRRGWAQSVAEREAGVASVSAPVLAPSGKLIAAVSVSGPIERLTRSPGRLHAPAVLAAAERLSEVLRRSGAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFC8</accession>
    <name>A0A1Q2CFC8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">23S rRNA (Cytidine1920-2'-O)/16S rRNA (Cytidine1409-2'-O)-methyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">TlyA family rRNA (Cytidine-2'-O)-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_08100</name>
        <name evidence="4" type="ORF">SAMN05428934_11360</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TlyA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ17147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08100"/>
    <dbReference type="EnsemblBacteria" id="AQP44770">
        <property type="protein sequence ID" value="AQP44770"/>
        <property type="gene ID" value="RPIT_08100"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ17147">
        <property type="protein sequence ID" value="SDZ17147"/>
        <property type="gene ID" value="SAMN05428934_11360"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08100"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004538">
        <property type="entry name" value="Haemolysin_A/TlyA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32319:SF0">
        <property type="entry name" value="PTHR32319:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005578">
        <property type="entry name" value="TlyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S4" evidence="2">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ17147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="238" mass="24884" checksum="D075CB23FBB6CB10" modified="2017-04-12" version="1">MRLDLALVERGLARSRTHAASLIREGLVSVNGKPAGKASQAVGDHDALSSTTDGWVSRAAHKLIGALDQSGTAVPGRVLDAGASTGGFTQVCLERGAETVYAVDVGHGQLVDSLQGDPRVRVREGLNLRDLTLDHLDGHPVDLIVGDVSFISLSLLLPSLAPTLAAGGSALLLVKPQFEVGRERLGSGGIVRDPALRVEAVDRIAAAAAQFGWREVWRGQSVLPGSAGNVEYFIKFTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFE1</accession>
    <name>A0A1Q2CFE1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type lipoprotein export system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_08460</name>
        <name evidence="6" type="ORF">SAMN05428934_1073</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY96202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08460"/>
    <dbReference type="EnsemblBacteria" id="AQP44823">
        <property type="protein sequence ID" value="AQP44823"/>
        <property type="gene ID" value="RPIT_08460"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY96202">
        <property type="protein sequence ID" value="SDY96202"/>
        <property type="gene ID" value="SAMN05428934_1073"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08460"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015854">
        <property type="entry name" value="ABC_transpr_LolD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24220:SF654">
        <property type="entry name" value="PTHR24220:SF654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY96202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="219" mass="23795" checksum="C03BE936D314B26D" modified="2017-04-12" version="1">MRTMQVAVKDLGVTYPISEGTLTVIDDFDLHVQSGQMVCLAGRSGSGKTSILKALAGFHVPTVGSVTWNGTDLRAMSPAEVADLRREHVGYMDQEAALLPELTALENCLVPILPDGRQAVRRARVRAREMLEALGLGERLGWRPAQLSGGERQRLVLARVFTQQTPAIIADEPTASLDRTWADRVIEHLRNHAHQGGLVVVASHDPAVSQAANQTMHLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFF2</accession>
    <name>A0A1Q2CFF2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA processing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">DNA protecting protein DprA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08535</name>
        <name evidence="3" type="ORF">SAMN05428934_10718</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DprA/Smf family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY96528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08535"/>
    <dbReference type="EnsemblBacteria" id="AQP44833">
        <property type="protein sequence ID" value="AQP44833"/>
        <property type="gene ID" value="RPIT_08535"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY96528">
        <property type="protein sequence ID" value="SDY96528"/>
        <property type="gene ID" value="SAMN05428934_10718"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08535"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009294">
        <property type="term" value="P:DNA-mediated transformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003488">
        <property type="entry name" value="DprA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43022">
        <property type="entry name" value="PTHR43022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02481">
        <property type="entry name" value="DNA_processg_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00732">
        <property type="entry name" value="dprA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY96528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="372" mass="38295" checksum="269AA1459AC3601E" modified="2017-04-12" version="1">MSSTDRQARMGLCALAPLGAPAVVRAVEEFGPVDIWEGFRAQGPDTAWGRRAQAVDLTQLDRATHLCGSRFLTPGDEEWPAPYAALAETTVSSQTGAPFGLWVRGRDLTALTGGVAIVGSRACTTYGEHAALTFAADLAAGGRTIISGLAFGIDAAAHRGALGMRGTTVAVVASGVDVPYPRGNRALADAIVGRGAIISELPPGYSPTRYAFLARNRLIAALSAAVVIVEAAHRSGAKNTTSWGNALGIPVLAVPGPITSSLSATPHRLIRDAEATLVTSADEVEAALAPLGTVPEPTGRGRDTPVDKLPPALFELREAVGGGETVGASQLAARTGQSMIEVLSNAAELVEGGWLEENPDGTFRLPGRPIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFJ7</accession>
    <name>A0A1Q2CFJ7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MarR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08875</name>
        <name evidence="3" type="ORF">SAMN05428934_10787</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08875"/>
    <dbReference type="EnsemblBacteria" id="AQP44889">
        <property type="protein sequence ID" value="AQP44889"/>
        <property type="gene ID" value="RPIT_08875"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98029">
        <property type="protein sequence ID" value="SDY98029"/>
        <property type="gene ID" value="SAMN05428934_10787"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08875"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY98029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="370" mass="38455" checksum="9A1D3D00D56D35B7" modified="2017-04-12" version="1">MLTDSEAALAEAVLLHGPITRQSLSSRLGLSAGSLTRLTKPFLARGLLVELKEAPDGLVGRPIKPLDIGRGLPFYAGVKITGDMVHSVATDVRANSLDNYDVTLQGHSPSTVVSAVAEAVAKLDVPRIAALGVSLGGSVSNGVVGRAPFLEWQDIPLQDMLEQALGMPVVLENDLVALAEAERWFGLGKDLPGFVIITIGAGIGYALAANNMVARSHDAGLGPAAHIPLSAAGPRCHEGHIGCAQAMLTDEFIAKAASTALGCAVDRDEAYALAQDEPAVRAVIEASGQALGRFIALAANLSLQSEVILAGEGIALFQLVEETVRATILDHRDPLASAVTLHVDDSGFGAWARGAAVVAIQSSLRRLDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFL2</accession>
    <name>A0A1Q2CFL2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aminopeptidase N</fullName>
            <ecNumber evidence="4">3.4.11.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Alanine aminopeptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Lysyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">RPIT_08930</name>
        <name evidence="17" type="ORF">SAMN05428934_10799</name>
    </gene>
    <organism evidence="16 18">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 18" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1T</strain>
        </source>
    </reference>
    <reference evidence="17 19" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">RP1</strain>
        </source>
    </reference>
    <reference evidence="16" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.</text>
            <dbReference type="EC" id="3.4.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M1 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.2" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08930"/>
    <dbReference type="EnsemblBacteria" id="AQP44898">
        <property type="protein sequence ID" value="AQP44898"/>
        <property type="gene ID" value="RPIT_08930"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98242">
        <property type="protein sequence ID" value="SDY98242"/>
        <property type="gene ID" value="SAMN05428934_10799"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08930"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012778">
        <property type="entry name" value="Pept_M1_aminopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="SSF63737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02412">
        <property type="entry name" value="pepN_strep_liv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M1_N" evidence="15">
        <location>
            <begin position="88"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1" evidence="13">
        <location>
            <begin position="237"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1_C" evidence="14">
        <location>
            <begin position="535"/>
            <end position="850"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="AQP44898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="SDY98242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="860" mass="94772" checksum="4B18B69CDFD8D252" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFL7</accession>
    <name>A0A1Q2CFL7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MarR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08995</name>
        <name evidence="3" type="ORF">SAMN05428934_107112</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08995"/>
    <dbReference type="EnsemblBacteria" id="AQP44911">
        <property type="protein sequence ID" value="AQP44911"/>
        <property type="gene ID" value="RPIT_08995"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98479">
        <property type="protein sequence ID" value="SDY98479"/>
        <property type="gene ID" value="SAMN05428934_107112"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08995"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY98479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="151" mass="16711" checksum="7C9B7E17C7698B17" modified="2017-04-12" version="1">MTEPQGGWLSESQQKTWRSYLLAKTHIEQYLEGALEDYGLSLPEYELLVRLSESPEHTIRMGELAASVGHSRSRLTHTVKRMEQAGYVVRESCASDGRGVQARMTESGYDLLKRAAPAHVDSVRRVFVDAIAPDDYAALGRAMSSVLAVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFQ7</accession>
    <name>A0A1Q2CFQ7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44944">
        <property type="protein sequence ID" value="AQP44944"/>
        <property type="gene ID" value="RPIT_09225"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09225"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025161">
        <property type="entry name" value="Put_IS4/IS5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13340">
        <property type="entry name" value="DUF4096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="193" mass="21566" checksum="D4131CF6FB3511E8" modified="2017-04-12" version="1">MSRLQTLSDAEWDLIEDFMPSSDGRRGRRFSDHRLVVEGIIYRYRTGVAWRDLPAEFGPWQTVWKRHRRFAGDGTWDKVLTALLTRADTMGVIDWDVAVDSTIARAHQHATNTRRLAGGSIELHDADARAGRSCDRAIAWRSVDEGPSAVRRQGTSHGHRRRAGARQRLEDVPAPARCGSGPARRGGAASHHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFR6</accession>
    <name>A0A1Q2CFR6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ketosteroid isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09280</name>
        <name evidence="3" type="ORF">SAMN05428934_1261</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
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                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">RP1</strain>
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    </reference>
    <reference evidence="2" key="3">
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
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    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09280"/>
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        <property type="gene ID" value="SAMN05428934_1261"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016853">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF54427"/>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="11"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ23632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="133" mass="13920" checksum="24A61294DE608C2D" modified="2017-04-12" version="1">MTDSTPATVAADYFDALSRGDVPAAMGLLSADVVWHQPGNHRFSGHHTGLNGVGALLGGMMEVSEGTFALTVTGPSMVNGNLVAVPVRFAGSRAEATMDMGGIDLLTVRDSKIVEVHLFSEDAATEDAFWGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFV7</accession>
    <name>A0A1Q2CFV7_9ACTN</name>
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        </submittedName>
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        <name evidence="10" type="ORF">SAMN05428934_102398</name>
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        <name type="scientific">Tessaracoccus flavus</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
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    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
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    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09540"/>
    <dbReference type="EnsemblBacteria" id="AQP44998">
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        <property type="gene ID" value="RPIT_09540"/>
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        <property type="gene ID" value="SAMN05428934_102398"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="DUF2510"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="180"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="221"/>
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        <location>
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            <end position="43"/>
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            <begin position="1"/>
            <end position="15"/>
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            <dbReference type="Pfam" id="PF10708"/>
        </source>
    </evidence>
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    </evidence>
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            <dbReference type="EMBL" id="SDY59705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="241" mass="26164" checksum="D871E0A2EE63DC32" modified="2017-04-12" version="1">MSNSPQQPPPGWYPDPAGADAERYWDGVAWSQSTRDRPRYAPPTPTPSAGGYGAEQRDYSYAQAPAGYGAGAPDPRLAGFGARMLGFILDSILIWILMSIIGRVTGLWARVTAEMELWMREVLIATESPGGALPGFSPGLTSALQILTIVSLALWFVYRFVLYLTMSATVGQLALGLRVVKVDKPVGTKLTAVESLIRALSSALLWGFSLTAFINPLFALFTKQKQTLSDLIAKTRVVKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFY9</accession>
    <name>A0A1Q2CFY9_9ACTN</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="4" type="ORF">SAMN05428934_102367</name>
    </gene>
    <organism evidence="3 5">
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        <lineage>
            <taxon>Bacteria</taxon>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">RP1T</strain>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="RPIT_09690"/>
    </dbReference>
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        <property type="gene ID" value="SAMN05428934_102367"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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            <end position="267"/>
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    </feature>
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        <location>
            <begin position="28"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY58873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="269" mass="29481" checksum="ED1D3D5925FE31E7" modified="2017-04-12" version="1">MEFSLLMFVVVMVLSIAGMGAGSRRRSIHMDPYQQGPPLGYPGDPMAQRQLPAPYGPQFGAPYGAQYQQPDYPMAPATRAALDSDITTYGDELRELDFDVVGRELSAEARQDYTRALDAYDGAKNQLARAQFASDVRRITQILDDGRYAIASVKARVNGQPLPEHRPPCFFDPAHGPSVENVQWAPPGGAARAVPACAADVARIRMGNDPSIRLVPMGAQQVPYWENQQYAPWVQGYYGRYGMDPALRQITHGALMIGGFSLLMGFLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG18</accession>
    <name>A0A1Q2CG18_9ACTN</name>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="2" type="ORF">SAMN05428934_102396</name>
    </gene>
    <organism evidence="1 3">
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY59653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09550"/>
    <dbReference type="EnsemblBacteria" id="AQP45000">
        <property type="protein sequence ID" value="AQP45000"/>
        <property type="gene ID" value="RPIT_09550"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59653">
        <property type="protein sequence ID" value="SDY59653"/>
        <property type="gene ID" value="SAMN05428934_102396"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09550"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021400">
        <property type="entry name" value="DUF3039"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11238">
        <property type="entry name" value="DUF3039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY59653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="80" mass="8876" checksum="40DF78A6DE596C4D" modified="2017-04-12" version="1">MSELAPGSQTVVDERTELFEDGDQDRFSHYVPKDKLTAALVNGTPVVALCGKVWVPSKNPEKYPVCPECKEIWQSLNPGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG60</accession>
    <name>A0A1Q2CG60_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribosomal-protein-alanine N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10040</name>
        <name evidence="3" type="ORF">SAMN05428934_102298</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10040"/>
    <dbReference type="EnsemblBacteria" id="AQP45087">
        <property type="protein sequence ID" value="AQP45087"/>
        <property type="gene ID" value="RPIT_10040"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56890">
        <property type="protein sequence ID" value="SDY56890"/>
        <property type="gene ID" value="SAMN05428934_102298"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10040"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY56890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="161" mass="17817" checksum="9008F3F2C1960189" modified="2017-04-12" version="1">MIVEVAGVADLDDIMALETHFDVRWSEESWIAELTGGGRLVLIARQREGGTVGVACFQLVDDVADLHRIVVDSAQRRMGFARVMLVAGMQWAIAQGASRMMLEVEHSNDAAVALYYGYGFRRVAQRDHYYGPGAHALIMERPLVGVDADSVGMWEMEDTDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG81</accession>
    <name>A0A1Q2CG81_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cytokinin riboside 5'-monophosphate phosphoribohydrolase</fullName>
            <ecNumber evidence="1">3.2.2.n1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10185</name>
        <name evidence="3" type="ORF">SAMN05428934_102268</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>9-ribosyl-trans-zeatin 5'-phosphate + H2O = D-ribose 5-phosphate + trans-zeatin</text>
            <dbReference type="Rhea" id="RHEA:48564"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16522"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:87947"/>
            <dbReference type="EC" id="3.2.2.n1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + N(6)-(dimethylallyl)adenosine 5'-phosphate = D-ribose 5-phosphate + N(6)-dimethylallyladenine</text>
            <dbReference type="Rhea" id="RHEA:48560"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17660"/>
            <dbReference type="ChEBI" id="CHEBI:57526"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="EC" id="3.2.2.n1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LOG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.n1" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10185"/>
    <dbReference type="EnsemblBacteria" id="AQP45113">
        <property type="protein sequence ID" value="AQP45113"/>
        <property type="gene ID" value="RPIT_10185"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56063">
        <property type="protein sequence ID" value="SDY56063"/>
        <property type="gene ID" value="SAMN05428934_102268"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10185"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009691">
        <property type="term" value="P:cytokinin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005269">
        <property type="entry name" value="LOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00730">
        <property type="entry name" value="TIGR00730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0203">Cytokinin biosynthesis</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY56063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="239" mass="26337" checksum="41C82535847E9A3A" modified="2017-04-12" version="1">MTVPKRRQGAVELRGKEHAQPMADQALLEGREKRWSQQDPWRVLRIQSEFVDGFDALQELEPAVSIFGSARTKPGTEMYELGEALGRGLVEKGFAVITGGGPGIMEAGNKGAFEAGGTSVGLGIELPHEQGMNDYITLGINFRYFFARKTMFLKYSRGFITMPGGFGTLDELFEALTLIQTGKVHNFPMVLFGTAYWTPLMDWVRHTVLDGGFVSAPDLDLVTLTDDVDEAIEAMGEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGB4</accession>
    <name>A0A1Q2CGB4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10310"/>
    <dbReference type="EnsemblBacteria" id="AQP45137">
        <property type="protein sequence ID" value="AQP45137"/>
        <property type="gene ID" value="RPIT_10310"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10310"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="136" mass="14619" checksum="5805333DEEF80AC6" modified="2017-04-12" version="1">MPPVIHVSAVVLRDRLGAVLFVRKRATTMWMNPGGKPEPGEDPAQCGAREVAEELGLHLDAERLVSMGALVAAAANEPGHAVMADVFEWPDPIDRGVQPAAEIDAVRWVGVEEFGDADLAPLFVEQIAPRLRSFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGC8</accession>
    <name>A0A1Q2CGC8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10455</name>
        <name evidence="2" type="ORF">SAMN05428934_102214</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY54570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45164">
        <property type="protein sequence ID" value="AQP45164"/>
        <property type="gene ID" value="RPIT_10455"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY54570">
        <property type="protein sequence ID" value="SDY54570"/>
        <property type="gene ID" value="SAMN05428934_102214"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10455"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY54570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="176" mass="19223" checksum="20337CA8A11EB965" modified="2017-04-12" version="1">MLPDVSRLRVRELLQVEASVVVELRQRGLVRTNNKPLGDIAEQVVLSARGGVLEPNSTKSHDVTDPGGRRIQVKAMGGRAAGKAGKFSPFRSFDFDIAVFLVFEFQTFELAFAREVSANDVEAVSPYSVHTNGRQPTLRQIENAGIDVTDEMRAAYAALDGDVMEFRNGLTSGGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGE2</accession>
    <name>A0A1Q2CGE2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">L-threonine dehydratase</fullName>
            <ecNumber evidence="11">4.3.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Threonine deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ilvA</name>
        <name evidence="13" type="ORF">RPIT_10505</name>
        <name evidence="14" type="ORF">SAMN05428934_102204</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>L-threonine = 2-oxobutanoate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:22108"/>
            <dbReference type="ChEBI" id="CHEBI:16763"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.3.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-isoleucine biosynthesis; 2-oxobutanoate from L-threonine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 11">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.19" evidence="11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY54260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10505"/>
    <dbReference type="EnsemblBacteria" id="AQP45173">
        <property type="protein sequence ID" value="AQP45173"/>
        <property type="gene ID" value="RPIT_10505"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY54260">
        <property type="protein sequence ID" value="SDY54260"/>
        <property type="gene ID" value="SAMN05428934_102204"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10505"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00054"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:L-threonine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1020.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011820">
        <property type="entry name" value="IlvA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001721">
        <property type="entry name" value="TD_ACT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038110">
        <property type="entry name" value="TD_ACT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00585">
        <property type="entry name" value="Thr_dehydrat_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02079">
        <property type="entry name" value="THD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51672">
        <property type="entry name" value="ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 11" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="8 11 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT-like" evidence="12">
        <location>
            <begin position="338"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP45173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY54260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="421" mass="45386" checksum="D4851DAD79AEF792" modified="2017-04-12" version="1">MSNLADLAAQIPDALARLDGVARRTPVHYNERMSSLTGSQIWLKREDLQPVRSYKLRGAYNLMSQLSAEEKAAGVVCPSAGNHGQGVAFAAAALEVHATVVVPHTTPRQKRQRIMEIGRGWVDLVMHGATYDEASEEAARMASEGMPLVPAFNDPRTAAGQATLMAEAFEQLGFVPDAVLLPVGGGGLLAGSAAWLRTNHPEVRIIGVEPEGAPCVAAAISAGRPITLTDIDTFVDGAAVKRVGDFTFEIIREAKVELVRVPEGQICTEMLEMYQTEGIIAEPAGALAAAALPTGGLGQRVQLPTGSRVLVLVSGGNNDVSRYAEVVERSLIHEGRKRYFLVDFPQQPGALRTFLDSVLGPDDDITYFEYVKRSSRDTGPALVGVELGNPNDYRFLLNRIAESGMKVDEVAYDSPFFRFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGH1</accession>
    <name>A0A1Q2CGH1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">ABC-2 type transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10770</name>
        <name evidence="3" type="ORF">SAMN05428934_102151</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY52612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10770"/>
    <dbReference type="EnsemblBacteria" id="AQP45218">
        <property type="protein sequence ID" value="AQP45218"/>
        <property type="gene ID" value="RPIT_10770"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY52612">
        <property type="protein sequence ID" value="SDY52612"/>
        <property type="gene ID" value="SAMN05428934_102151"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10770"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY52612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="277" mass="28981" checksum="D8612A0ECAFA6566" modified="2017-04-12" version="1">MSRARGSFWRLVRSDLRLLFGRRRTLALLAGLALVPLLLAVVLFVASNSGMSGQGPGFIDRVTGNGLFLVIAALFMCLPFLLPLTIGITAGDAISGEAQAGTLRYVLTVPVARTRLLVAKALVSLSFALAAVLVITVVALAAGGAFFGFSEMTLLSGTTVSLGAGVARMLGVAAYVALSLTGLVAVGLFFSTLTEVPVGAMAATTVVAVVSSVLDTLPQLSTIHPYLLTHHWFDFAEFLRLEIDWGVLGSGLLVQLGWVAIFASLAWGRFKTADVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGH2</accession>
    <name>A0A1Q2CGH2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADPH-dependent ferric siderophore reductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10735</name>
        <name evidence="3" type="ORF">SAMN05428934_102158</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY52837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10735"/>
    <dbReference type="EnsemblBacteria" id="AQP45211">
        <property type="protein sequence ID" value="AQP45211"/>
        <property type="gene ID" value="RPIT_10735"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY52837">
        <property type="protein sequence ID" value="SDY52837"/>
        <property type="gene ID" value="SAMN05428934_102158"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10735"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013113">
        <property type="entry name" value="FAD-bd_9_SIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007037">
        <property type="entry name" value="SIP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039374">
        <property type="entry name" value="SIP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30157">
        <property type="entry name" value="PTHR30157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08021">
        <property type="entry name" value="FAD_binding_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04954">
        <property type="entry name" value="SIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="1">
        <location>
            <begin position="6"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY52837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="279" mass="30577" checksum="AF0AE2ACB02D15C4" modified="2017-04-12" version="1">MSQRTRPLRRAVVVRTERVAPEMVRLTLHSDQMRGHELPFCDHYVKFLFPPAGAPYDRPFDPETVRDQFPPEHWPVTRTYTIRSADPATGEFVVDVVLHGDAGLAGPWAAQAQPGDEIGFHGPGGAWAPSDHAHYVFAGDEAAAPAICRGVELLPGGATATVYLEIADERGRFPVPQREGVTVRWVLRDGAAYGQALASVVRAGGAPDGAGWFVHGVAEMVKDVRHFLFVEQGVPRSDVSISGYWRTGMTEDGWRQTKRDFVAEMETAEIADLATAARH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGJ0</accession>
    <name>A0A1Q2CGJ0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tocopherol cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10805</name>
        <name evidence="2" type="ORF">SAMN05428934_102144</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY52352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45224">
        <property type="protein sequence ID" value="AQP45224"/>
        <property type="gene ID" value="RPIT_10805"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY52352">
        <property type="protein sequence ID" value="SDY52352"/>
        <property type="gene ID" value="SAMN05428934_102144"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10805"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009976">
        <property type="term" value="F:tocopherol cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025893">
        <property type="entry name" value="Tocopherol_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35309">
        <property type="entry name" value="PTHR35309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14249">
        <property type="entry name" value="Tocopherol_cycl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY52352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="332" mass="35817" checksum="3226D6EFB5289669" modified="2017-04-12" version="1">MALLGYRSSGADLPYGHPEWAHGVAMEGYFWRITDPSAQRTVIALIGVQTDRSGRWALTGLGASDGFWRHDVLPIAEARPAGLGARASGPGRSFVGTDERVTVDLGPDATLDIQLDGLNRWPARRAFGGSSVFQTIPGLNQYWHPWLLGGRASGSVTVGDQHWSFDDAHIYGEKNWGKGGFPESWWWGQAQGFEEPGACVAFAGGDVVAGPFRTEVTGLVVRLPHGRVIRLGNPGTSPVVADVGDEHWHLAGRSRDWTVRIEADAPLTDAHVLPVPLVGERRAVPGAIEHLSGRLRVEVSRRGRLVWSDESTLAGLEHGGLDRAAALAESRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGJ8</accession>
    <name>A0A1Q2CGJ8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">4Fe-4S dicluster domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_10825</name>
        <name evidence="6" type="ORF">SAMN05428934_102139</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY52195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10825"/>
    <dbReference type="EnsemblBacteria" id="AQP45227">
        <property type="protein sequence ID" value="AQP45227"/>
        <property type="gene ID" value="RPIT_10825"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY52195">
        <property type="protein sequence ID" value="SDY52195"/>
        <property type="gene ID" value="SAMN05428934_102139"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10825"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="144"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="176"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY52195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="279" mass="29249" checksum="DB4642B2C38B4020" modified="2017-04-12" version="1">MSEASHAAILRWLDAAEPAEITLSCAESPLPGAVILDRCLAEVPAAWVAELATHCPVRAAVDHCARPEVARSRLAELASVTTAITLDGGPSSGHPVRYTHPPARRRALFGLGSTTPAPSGTLAERLAAALSRLPLTLEAESPAARLRITRDCTACGLCARSCPHGALGFAVVEGVAAIHHKLDACQGDGTCVAVCPEDAIVRDGTHRWAEVRDHPVVEVTALPVLRCGKCNAPFADNSDTPSALCPVCRVTAAEPFGVHLTPTARALLERRRRGGADTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGS2</accession>
    <name>A0A1Q2CGS2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11360</name>
        <name evidence="3" type="ORF">SAMN05428934_10231</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY48943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11360"/>
    <dbReference type="EnsemblBacteria" id="AQP45319">
        <property type="protein sequence ID" value="AQP45319"/>
        <property type="gene ID" value="RPIT_11360"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY48943">
        <property type="protein sequence ID" value="SDY48943"/>
        <property type="gene ID" value="SAMN05428934_10231"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11360"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY48943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="86" mass="9464" checksum="055545C59B1422BD" modified="2017-04-12" version="1">MEDTNLQELRDAVAALTAQVKALEDRVSQLESQHEIPESDLVAIGAAVAAYFGHKAKVRAIRYGSQSRWAAASRGRVHDRSVPHVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGU7</accession>
    <name>A0A1Q2CGU7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LacI family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_11405</name>
        <name evidence="6" type="ORF">SAMN05428934_10223</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY48674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11405"/>
    <dbReference type="EnsemblBacteria" id="AQP45327">
        <property type="protein sequence ID" value="AQP45327"/>
        <property type="gene ID" value="RPIT_11405"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY48674">
        <property type="protein sequence ID" value="SDY48674"/>
        <property type="gene ID" value="SAMN05428934_10223"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11405"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="4"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY48674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="334" mass="34728" checksum="84C0F18F65A14250" modified="2017-04-12" version="1">MRRVTITDVARAAGVSVSTISKVMNGRDGIAPATQLRVQRVIDELGYVGNVGAQSLRARRTGVIGVLVSQFEPYSAEVLKGIGRAAEGTEHEIMAWAGASHNPHAPTGWEQKLLGRLAGSLIDGAIIVTPSVAADSGTFPVVAVDPQEALPTIPSVAVDDEGGTRSAVRHLIELGHSRIGYLGGRDDLASAAAREQGFRAAMAEAGLVVDESLVQVGDYSGVGAVLPAAALLDHPERPTAIVAANDVSAIQVMTAAASRKMVVPDDLSVVGFDDVPEASWHVPGLTTVAQPLRSIGALALKTMLELLAGRDLDEPHLRLPTHLVVRGSTAALRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGW1</accession>
    <name>A0A1Q2CGW1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polyisoprenoid-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Polyisoprenoid-binding protein YceI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11585</name>
        <name evidence="3" type="ORF">SAMN05428934_106158</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY94141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11585"/>
    <dbReference type="EnsemblBacteria" id="AQP45359">
        <property type="protein sequence ID" value="AQP45359"/>
        <property type="gene ID" value="RPIT_11585"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY94141">
        <property type="protein sequence ID" value="SDY94141"/>
        <property type="gene ID" value="SAMN05428934_106158"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11585"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036761">
        <property type="entry name" value="TTHA0802/YceI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04264">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00867">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101874">
        <property type="entry name" value="SSF101874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YceI" evidence="1">
        <location>
            <begin position="9"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY94141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="180" mass="19872" checksum="CB8F7352167E435E" modified="2017-04-12" version="1">MQLNELNGTYVLDPTHTTLSFVTRHAMVTKVRGSFEEFEGQAVIDAANPQATTLEVKINPASVNTRNEDRDNHVRSADFFDVEKYPTWTFVGTSYAVQGDTVEVTGDLTIKDITRSITIPLEYQGSAKDPFGNDRVGFEGSVQVNRSDFGLTWNAALETGGFLVSDKITLEFEISAIKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH02</accession>
    <name>A0A1Q2CH02_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Maltose alpha-D-glucosyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Maltose alpha-D-glucosyltransferase/ alpha-amylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_11805</name>
        <name evidence="4" type="ORF">SAMN05428934_106114</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11805"/>
    <dbReference type="EnsemblBacteria" id="AQP45399">
        <property type="protein sequence ID" value="AQP45399"/>
        <property type="gene ID" value="RPIT_11805"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93172">
        <property type="protein sequence ID" value="SDY93172"/>
        <property type="gene ID" value="SAMN05428934_106114"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11805"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012665">
        <property type="entry name" value="Trehalose_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02455">
        <property type="entry name" value="TreS_stutzeri"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aamy" evidence="2">
        <location>
            <begin position="163"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY93172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="760" mass="83463" checksum="0B9E78C823823BB4" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH15</accession>
    <name>A0A1Q2CH15_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperone protein DnaJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dnaJ</name>
        <name evidence="11" type="ORF">RPIT_11920</name>
        <name evidence="12" type="ORF">SAMN05428934_10691</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 2 Zn(2+) ions per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DnaJ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11920"/>
    <dbReference type="EnsemblBacteria" id="AQP45418">
        <property type="protein sequence ID" value="AQP45418"/>
        <property type="gene ID" value="RPIT_11920"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92682">
        <property type="protein sequence ID" value="SDY92682"/>
        <property type="gene ID" value="SAMN05428934_10691"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11920"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
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    <keyword evidence="3 6" id="KW-0677">Repeat</keyword>
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    <keyword evidence="5 6 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 6 7" id="KW-0863">Zinc-finger</keyword>
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            <end position="232"/>
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            <end position="173"/>
        </location>
    </feature>
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            <end position="190"/>
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        </location>
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        </location>
    </feature>
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    </feature>
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        <location>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:29105"/>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
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    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="382" mass="40550" checksum="AF7FC5480346CA1E" modified="2017-04-12" version="1">MSTKDWLEKDYYKILGVSKTATSDEIKKAFRKIARDNHPDQNPGNKAAETRFKEASEANSVLSDADKRKEYDEARSLFGGGFRFNKPGQPGAAGFEDIFRNAGGATNPGFGDLFGGLFGAHDGPTRRATQRGPRRGADIEGDVTISFEQAVEGATVTMRTVSDRPCPGCRGTGAKAGTLPRVCPTCEGSGMQSSRSGGVFQMSEPCVDCLGRGLIVDEPCPDCDGSGRGRSTKTMQVRIPAGVSDGQRIRIKGKGAAGENGGAPGDLYVGVKVTPHKLFGRSGSNLTLEVPVTFTEASLGAEIQVPTLSGTKIRLRIPPSTPNGRTMRVRGKGARKPDGTMGDLLVTIDVQVPDDLSEEAKAALQEYAEKAHETNPRDALFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH39</accession>
    <name>A0A1Q2CH39_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12025</name>
        <name evidence="3" type="ORF">SAMN05428934_10670</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY92185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45438">
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        <property type="gene ID" value="RPIT_12025"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92185">
        <property type="protein sequence ID" value="SDY92185"/>
        <property type="gene ID" value="SAMN05428934_10670"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12025"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="TRX_Fd_Sucrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009737">
        <property type="entry name" value="Aim32/Apd1-like"/>
    </dbReference>
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        <property type="entry name" value="Aim32/Apd1-like_bac"/>
    </dbReference>
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        <property type="entry name" value="Apd1-like"/>
    </dbReference>
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        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP45438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY92185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="305" mass="33418" checksum="95AB41769742654A" modified="2017-04-12" version="1">MTRSSLPLSVEPASTDRGYRCSTGSRERGEPLTATASTVSRFLLMEEPGPWGPAVLNCYRVPDPVRQLAESWEREFGIRPLLIRRPGRSAPAPRRIFVVNAAHGWAQTTTVESLDDVASLDLSGIGSSAGVGLTPHVDPVLLVCTHGRHDACCAERGRPVAAELARRWPDLVWESSHLGGDRFAANLVTLPDGHYYGRMEPDSAVDVVERHLSGHLTPRFHRGRSIRPWVAQAAEAAVRERLGETRLDAVRTHVLRREASWAEVEVFVGESRYVEVVDVARADPALLTCTSPLPSAAPTYVVRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH49</accession>
    <name>A0A1Q2CH49_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Osmoprotectant transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_11730</name>
        <name evidence="7" type="ORF">SAMN05428934_106129</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11730"/>
    <dbReference type="EnsemblBacteria" id="AQP45385">
        <property type="protein sequence ID" value="AQP45385"/>
        <property type="gene ID" value="RPIT_11730"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93523">
        <property type="protein sequence ID" value="SDY93523"/>
        <property type="gene ID" value="SAMN05428934_106129"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11730"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="59"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="27"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY93523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="230" mass="23267" checksum="10C7918D57103DA3" modified="2017-04-12" version="1">MNLFADAAAWLADPANWTGPSGLPTRLLEHLLITAAAVCIAAAVAIPAGLLVGHTGRGAGVVGAVAGGARAIPSLGLLTLFGLWLGIGLEAPLLTLVVLALPSLLAGTYSGVQAIDSSIPAAARAVGHSPAQVLLTVEVPLALPVILGGLRAATLQVVATATLAAYTADFGLGRYLFAGLKSRDYPQMLGGSLVVIVLALALEILFAVFQRIASRKAWPGRTQTRALATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH63</accession>
    <name>A0A1Q2CH63_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45452">
        <property type="protein sequence ID" value="AQP45452"/>
        <property type="gene ID" value="RPIT_12095"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12095"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="113" mass="11692" checksum="A16D1F754110CD57" modified="2017-04-12" version="1">MFLGVVTYGTLASVRLHGNAIDDMTLMLALMSVALVGVLAAFVLSILSVARRRDARSGIALAASVVLPVAATSLGIAIGIQVLQYNIGHSIEALTSSADVAGRLITRLLELFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHE4</accession>
    <name>A0A1Q2CHE4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Heterodimeric methylmalonyl-CoA mutase large subunit</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">Methylmalonyl-CoA mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_12595</name>
        <name evidence="11" type="ORF">SAMN05428934_104167</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-methylmalonyl-CoA = succinyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:22888"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:57326"/>
            <dbReference type="EC" id="5.4.99.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Metabolic intermediate metabolism; propanoyl-CoA degradation; succinyl-CoA from propanoyl-CoA: step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY79659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12595"/>
    <dbReference type="EnsemblBacteria" id="AQP45539">
        <property type="protein sequence ID" value="AQP45539"/>
        <property type="gene ID" value="RPIT_12595"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY79659">
        <property type="protein sequence ID" value="SDY79659"/>
        <property type="gene ID" value="SAMN05428934_104167"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12595"/>
    <dbReference type="UniPathway" id="UPA00945">
        <property type="reaction ID" value="UER00910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004494">
        <property type="term" value="F:methylmalonyl-CoA mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006159">
        <property type="entry name" value="Acid_CoA_mut_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016176">
        <property type="entry name" value="Cbl-dep_enz_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006099">
        <property type="entry name" value="MeMalonylCoA_mutase_a/b_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006098">
        <property type="entry name" value="MMCoA_mutase_a_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01642">
        <property type="entry name" value="MM_CoA_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51703">
        <property type="entry name" value="SSF51703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00640">
        <property type="entry name" value="acid_CoA_mut_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00641">
        <property type="entry name" value="acid_CoA_mut_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00544">
        <property type="entry name" value="METMALONYL_COA_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="8" id="KW-0170">Cobalt</keyword>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B12-binding" evidence="9">
        <location>
            <begin position="596"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP45539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY79659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="727" mass="79842" checksum="9D91DD88E7BBFDEF" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHI0</accession>
    <name>A0A1Q2CHI0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Beta-glucosidase</fullName>
            <ecNumber evidence="3 11">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_12755</name>
        <name evidence="13" type="ORF">SAMN05428934_104136</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the glycosyl hydrolase 1 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="3 11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY78754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12755"/>
    <dbReference type="EnsemblBacteria" id="AQP45567">
        <property type="protein sequence ID" value="AQP45567"/>
        <property type="gene ID" value="RPIT_12755"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY78754">
        <property type="protein sequence ID" value="SDY78754"/>
        <property type="gene ID" value="SAMN05428934_104136"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12755"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102483">
        <property type="term" value="F:scopolin beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001360">
        <property type="entry name" value="Glyco_hydro_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018120">
        <property type="entry name" value="Glyco_hydro_1_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017736">
        <property type="entry name" value="Glyco_hydro_1_beta-glucosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033132">
        <property type="entry name" value="Glyco_hydro_1_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353">
        <property type="entry name" value="PTHR10353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00232">
        <property type="entry name" value="Glyco_hydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00131">
        <property type="entry name" value="GLHYDRLASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03356">
        <property type="entry name" value="BGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00572">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00653">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="428"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8 10">
        <location>
            <position position="374"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="421"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR617736-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR617736-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP45567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY78754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="470" mass="52059" checksum="5B66CF9B4EC469F9" modified="2017-04-12" version="1">MTTYQFPQGFLWGSATAAYQIEGAAHEDGRRDSIWDVFCREPGTVAGGDDGSVACDHYHRMPTDVAMMAELGLQSYRFSTSWSRVRPDDAEFNPKGLDFYSRLVDELLGHGITPWVTLYHWDLPAALQAKGGWTNRDTAYRFVEYAEAMHGAIGDRVDVWTTLNEPWCSSFLSYACGEHAPGHADRTEGLHAGHHLLLAHGLATARLRELAPSATLGITLNHTVPDPVDPSSETDQEAARRIDGIFNRFFLDPIFRGSYPEDVLRDIAGLGLDEVVKPGDLELIAAPIDVLGVNYYHGSAVTGTPSSDYAPAVLPDGRVRGNPNIGSEWVTFQPRDLPVTDQGWEIQPEGLTRLLVRLHEEYTGPAGVALYVTENGAAMPDLVDENGFVDDQDRVSFVRDHLIAVHDAIEKGVDVRGYFVWSLMDNFEWAWGYDKRFGIVRVDYATQKRTPKASALFFRDAARDNAVEGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHP7</accession>
    <name>A0A1Q2CHP7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_12880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45590">
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        <property type="gene ID" value="RPIT_12880"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MM3350-like_sf"/>
    </dbReference>
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        <property type="entry name" value="Plasmid_pRiA4b_Orf3"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07929">
        <property type="entry name" value="PRiA4_ORF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159941">
        <property type="entry name" value="SSF159941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="474" mass="52296" checksum="A1F7DAA3EFEBD198" modified="2017-04-12" version="1">MREMAQDGDRQRQIDELADQIIAESGGIDGLLVRLGAHPGMALPTQRQPTLLPPRAERVAYVLRIELEYIEPPIWRQVVVPSDLTLDALHDVLQAAMGWTDSHLHAFRMGPGELEHNIAPFVTQFDIEEGDDGTPEVDVRLDEVLGSLGDRLSYEYDFGDGWEHRIILESIQAEPFTEVRCLAGERACPPEDVGGVPGYERLLDVLAGRAHDVDPAWAQTLRDWAPPGFDPECFDVNEANEALDGIEWPTMEGWRSEVLGLIVRLSVEQPTLVRKLAVAVDRREPISDEQVEEVVADLRLLLERVGSDGIKLTQAGYLPPKVVKELFAGLRPEVLQRYPFQPTTEINTPPVLNLREAAMGVGLVRKYKGVLVLTPKGRTAIEAPEKLWRAVVDGIPVGKRQYEVDAGLIELLGVAGGLDVWRDRETLGDMFAAAGWRSDAPMEWAYRDAASGTRRLLSILGGGATVAAAIIRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHS0</accession>
    <name>A0A1Q2CHS0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arsenical resistance operon trans-acting repressor ArsD</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Arsenical resistance operon transcriptional repressor ArsD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_12975</name>
        <name evidence="2" type="ORF">SAMN05428934_10492</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12975"/>
    <dbReference type="EnsemblBacteria" id="AQP45605">
        <property type="protein sequence ID" value="AQP45605"/>
        <property type="gene ID" value="RPIT_12975"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY77557">
        <property type="protein sequence ID" value="SDY77557"/>
        <property type="gene ID" value="SAMN05428934_10492"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12975"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046685">
        <property type="term" value="P:response to arsenic-containing substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010712">
        <property type="entry name" value="Arsenical-R_ArsD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06953">
        <property type="entry name" value="ArsD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY77557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="144" mass="14685" checksum="3C0EE0A4A6B13F07" modified="2017-04-12" version="1">MPAIHVFEPALCCNTGVCGPELDESLVRFTADLDHLRSAGVDITRHNLANDPTAFATNPVVVNFLQVAGSPGLPLVLVDDVTVAAGRYPSRAELLRYAERPELGDLGLASAGSCCGSGPDDTAEVATGCCGGAPESAAARAACC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHS9</accession>
    <name>A0A1Q2CHS9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GntR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13290</name>
        <name evidence="3" type="ORF">SAMN05428934_10429</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY75793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13290"/>
    <dbReference type="EnsemblBacteria" id="AQP45664">
        <property type="protein sequence ID" value="AQP45664"/>
        <property type="gene ID" value="RPIT_13290"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY75793">
        <property type="protein sequence ID" value="SDY75793"/>
        <property type="gene ID" value="SAMN05428934_10429"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13290"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011663">
        <property type="entry name" value="UTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07702">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00866">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="21"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY75793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="287" mass="31160" checksum="1739680FD0392546" modified="2017-04-12" version="1">MRREPAVWSPQHLSFSRDDGLPKYIAIARAIGQAITEEELKPGEYLPSQKELAESFGVTVMTVRQAIQLLIDQGKLSAEQGKGTYVQSRSYRLPMGPLASFAAQMSAAGMSLRTEVLGFGPIEISPLEQKRMGLPTAKAFELVRLRIVDGEPLVLQTSLLPPAVAAGITPSELETRSLYDVLHSELGIRIKRATETVQATQLDAESAGLLRRTVGEAALLSARLTFSEENNAVIDDRALTAGNRVVIAAEREAGDSPLSLQLFTQDTSLHETTPFVRGTGDHRQAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHT5</accession>
    <name>A0A1Q2CHT5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Small conductance mechanosensitive channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_13105</name>
        <name evidence="9" type="ORF">SAMN05428934_10466</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY76837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13105"/>
    <dbReference type="EnsemblBacteria" id="AQP45630">
        <property type="protein sequence ID" value="AQP45630"/>
        <property type="gene ID" value="RPIT_13105"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY76837">
        <property type="protein sequence ID" value="SDY76837"/>
        <property type="gene ID" value="SAMN05428934_10466"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13105"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045276">
        <property type="entry name" value="YbiO_bact"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30460">
        <property type="entry name" value="PTHR30460"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY76837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="293" mass="31109" checksum="5FF8ED7730C498D1" modified="2017-04-12" version="1">MGDLWENLMLAAVVITVALLLRVFLALVIRRTVRVLADRVHDRNDDDLGFRARVLLAKASGVAADRQRQRVETLGSLLRNVVDVALIVVVVLTVLAIFGVPMGPLIASAGVGGVALGFGAQSLVKDYLSGIFMLAEDQFGVGDLIKVGDLTGTVQEVTLRVTKLRDTTGTVWYVRNGEVLTLGNVSQGYSTAIVDVPVANDEDPSRVQEVLRAALAGMDKEPEFSDQLLEEPSVLGVGSVTAGTMTMQVLLKTGPNQQWGPTRAVRERAQRALADAGVRGPILAGPYGPGSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHX3</accession>
    <name>A0A1Q2CHX3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GntR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13545"/>
    <dbReference type="EnsemblBacteria" id="AQP45707">
        <property type="protein sequence ID" value="AQP45707"/>
        <property type="gene ID" value="RPIT_13545"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13545"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="63"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="437" mass="47600" checksum="950DF7EB02016819" modified="2017-04-12" version="1">MTVTDHPRYDTRLDRYVDSYAQRTNGMRVSAVRALFAVANRPEIVSLAGGMPNIKDLPLGDIADSMAEMIRTRGTQVMQYGSGQGEPELREQILDVMALEGIVAHPDDLVITAGSQQGLDLVTRIFCDPGDVVLAESPSYVGALGTFLSYQVEVVHVPSDDQGLDPVALVETIARVKAAGKRIKFLYTIPNYNNPSGVTQSARRRLDIVAACRAAGVLVVEDNPYGLLALDAEPIPAMRSAADDVIYLGSFSKTFAPGFRVGWVLAPHAVREKLVLAQESATLCPPVFSQFAISNYLANHDWKGQVVVFRDMYRGRRDAMLSALEEEMPPGTSWTRPAGGFFVWVTLPEGLDSQAMLPRGVDARVAFVPGSAFYADGQGARNVRLSFCFPPAERIEVGVQRFAEVVRRELDMMDIFGVHSPAPIEPHRPAGPGPDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHZ0</accession>
    <name>A0A1Q2CHZ0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Single-stranded DNA-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">SpoIIIJ-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_13580</name>
        <name evidence="5" type="ORF">SAMN05428934_11183</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ13094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13580"/>
    <dbReference type="EnsemblBacteria" id="AQP45714">
        <property type="protein sequence ID" value="AQP45714"/>
        <property type="gene ID" value="RPIT_13580"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ13094">
        <property type="protein sequence ID" value="SDZ13094"/>
        <property type="gene ID" value="SAMN05428934_11183"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13580"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02414">
        <property type="entry name" value="jag_KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02644">
        <property type="entry name" value="R3H_jag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038008">
        <property type="entry name" value="Jag_KH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039247">
        <property type="entry name" value="KhpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034079">
        <property type="entry name" value="R3H_KhpB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35800">
        <property type="entry name" value="PTHR35800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00393">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="SSF82708"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0133">Cell shape</keyword>
    <keyword evidence="2" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="R3H" evidence="3">
        <location>
            <begin position="92"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ13094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="156" mass="17043" checksum="3861FBA19F47346F" modified="2017-04-12" version="1">MSNNETEAELLAEGDLVADYFEELLDIADLDGDIENSVQDGRAFVAIDTESERLVGKDGEVLEALQELARLVVMTETGNRSRLMVDVAGYRARRRAELVAMAKDAIADVSDSGEPVRMVPLNAYERKIVHDEVAAAGLLSESEGEPPNRRVVVKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHZ5</accession>
    <name>A0A1Q2CHZ5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_13455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45693">
        <property type="protein sequence ID" value="AQP45693"/>
        <property type="gene ID" value="RPIT_13455"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13455"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="82" mass="9038" checksum="5F6AAC9191476AF2" modified="2017-04-12" version="1">MEPGDVLVAKQMNNDFATMLVKAIGVVTEPATDGHRVGVDWVRDFRSAPVTLPSSYRQTLTRVSDTPASRTLIKDHILPLMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI65</accession>
    <name>A0A1Q2CI65_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pilus assembly protein, ATPase of CpaF family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Secretion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_14230</name>
        <name evidence="4" type="ORF">SAMN05428934_11228</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ14722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14230"/>
    <dbReference type="EnsemblBacteria" id="AQP45818">
        <property type="protein sequence ID" value="AQP45818"/>
        <property type="gene ID" value="RPIT_14230"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ14722">
        <property type="protein sequence ID" value="SDZ14722"/>
        <property type="gene ID" value="SAMN05428934_11228"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14230"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="207"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ14722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="485" mass="52688" checksum="D233AB7F2AF6992F" modified="2017-04-12" version="1">MSISELPSLAGALGRLGVAPEPYETPSSAAQVSEPPARRSVVEPVPSSLDIDWQLVVGLRREAAESISRAAAEWLAERGAPMPEADRRVQGRAIIRSVVHARAQSLSEAGEALWPIELETRYADAVESAIFGYGRLQPLFDIADAENIEIHGCDNVMVQYGDGHRERFPAVADTDDELVDAIRFLGETASPPRPFDDLHPTMTLALGNRFRLHAIGFGLSYRPSVVIRQHLLTDVTLDDLADGGMLPRDVARLLRAAVLGRKSIVISGDQGAGKTTLLRALIAAIHPRERFGTLETDYELLTHLLDDRRNVLALQARIGMGETSGDGSVGTYTVADLIPEALRQNLTRLIVGEVRGAEAGAMFEAMQSGAGTLSTTHSHSASSTIDRLAARVAQGRVLSIEDAMRQIAHHIDFIVHVSLQDDAWRGGVRRRYVSEIRQLTGAVEAGRPTTHLVYRAATESSAELFQPEASMAADLAPFDRAESWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI91</accession>
    <name>A0A1Q2CI91_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Fumarate hydratase class I</fullName>
            <ecNumber evidence="10">4.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">RPIT_14090</name>
        <name evidence="14" type="ORF">SAMN05428934_1172</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reversible hydration of fumarate to (S)-malate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(S)-malate = fumarate + H2O</text>
            <dbReference type="Rhea" id="RHEA:12460"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="4.2.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the class-I fumarase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="10"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000017">
        <property type="protein sequence ID" value="SDZ20732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14090"/>
    <dbReference type="EnsemblBacteria" id="AQP45793">
        <property type="protein sequence ID" value="AQP45793"/>
        <property type="gene ID" value="RPIT_14090"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ20732">
        <property type="protein sequence ID" value="SDZ20732"/>
        <property type="gene ID" value="SAMN05428934_1172"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14090"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006091">
        <property type="term" value="P:generation of precursor metabolites and energy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004646">
        <property type="entry name" value="Fe-S_hydro-lyase_TtdA-typ_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004647">
        <property type="entry name" value="Fe-S_hydro-lyase_TtdB-typ_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036660">
        <property type="entry name" value="Fe-S_hydroAse_TtdB_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011167">
        <property type="entry name" value="Fe_dep_fumarate_hydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05681">
        <property type="entry name" value="Fumerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05683">
        <property type="entry name" value="Fumerase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001394">
        <property type="entry name" value="Fe_dep_fumar_hy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117457">
        <property type="entry name" value="SSF117457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00723">
        <property type="entry name" value="ttdB_fumA_fumB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumerase" evidence="11">
        <location>
            <begin position="50"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Fumerase_C" evidence="12">
        <location>
            <begin position="335"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP45793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDZ20732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="566" mass="61368" checksum="502313D8C7DFE756" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CII0</accession>
    <name>A0A1Q2CII0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Na+/H+ antiporter subunit E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_14455</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14455"/>
    <dbReference type="EnsemblBacteria" id="AQP45860">
        <property type="protein sequence ID" value="AQP45860"/>
        <property type="gene ID" value="RPIT_14455"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14455"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002758">
        <property type="entry name" value="Cation_antiport_E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34584">
        <property type="entry name" value="PTHR34584"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01899">
        <property type="entry name" value="MNHE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="197" mass="22498" checksum="FFEAD592236D6ED4" modified="2017-04-12" version="1">MRSATPWRDRLRFRPLSVFGMTLMWMLLWGSASPVIVLSGMLIGYLIDIVFPLPPIFWQGKLRPLGVVVLVFHLLWDLVVSSFRVVALVFHRRVNLNAGIVRVDLHSDNDLYQVQVAEMISLVPGTVVVEVVRSPRRLYLHVIDLVGDEPLARVQRMVFDVESRVLRAFGSDEEIAQFNEALELHPDPRATEMEVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIJ1</accession>
    <name>A0A1Q2CIJ1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00060</name>
        <name evidence="3" type="ORF">SAMN05428934_10933</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00060"/>
    <dbReference type="EnsemblBacteria" id="AQP45931">
        <property type="protein sequence ID" value="AQP45931"/>
        <property type="gene ID" value="RPIT_00060"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05238">
        <property type="protein sequence ID" value="SDZ05238"/>
        <property type="gene ID" value="SAMN05428934_10933"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00060"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ05238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="86" mass="9432" checksum="E6F464F419CBDFEF" modified="2017-04-12" version="1">METNQNEELAAQVAALAEQVATLQARLAALEEKQEIPEADLVAIGAAVAAYFGHKAKIRAVRFGSQSRWAAATRERAHDRRVPHVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIJ7</accession>
    <name>A0A1Q2CIJ7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MOSC domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">MOSC domain-containing protein YiiM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00135</name>
        <name evidence="4" type="ORF">SAMN05428934_10918</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ04866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00135"/>
    <dbReference type="EnsemblBacteria" id="AQP45932">
        <property type="protein sequence ID" value="AQP45932"/>
        <property type="gene ID" value="RPIT_00135"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ04866">
        <property type="protein sequence ID" value="SDZ04866"/>
        <property type="gene ID" value="SAMN05428934_10918"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00135"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MOSC" evidence="2">
        <location>
            <begin position="33"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ04866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="212" mass="22919" checksum="EEA56DCF1DCCDBBD" modified="2017-04-12" version="1">MILSTNVAVSQRDPGGADRVSGIDKRPQPFIDVRAPGPSYGDGSGVDGDTVGDSAHHGGAQKAVYAYAREELDYWQAELGRELPNGSFGENLTTVGLDLAAMLVNQRLHIGTAVLEISIVRQPCRTFAAWLGERGWVKRFSQRGRCGAYLRVIAPGRITAGDVIEVVGRPEHDIDMLTAFRAAQGDKEAARSVVAANCLPPLYHRRLVKLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIR5</accession>
    <name>A0A1Q2CIR5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_00530</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00530"/>
    <dbReference type="EnsemblBacteria" id="AQP45940">
        <property type="protein sequence ID" value="AQP45940"/>
        <property type="gene ID" value="RPIT_00530"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00530"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03220">
        <property type="entry name" value="ABC_KpsT_Wzt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015860">
        <property type="entry name" value="ABC_transpr_TagH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="32"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="65"/>
            <end position="72"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="259" mass="27999" checksum="3905A07AF6116329" modified="2017-04-12" version="1">MTHVDPAIIVDDLHITYKVNLERKNSLKNALVKGMKGEKVNYREVRALRGVTFDVPKGQCTGVIGANGAGKSTLMRAVAGILPPTKGRIEIDGKVSTLLALGVGFNTALTGRENVVLGGLAAGLTRAEVKAKFDEIAAFADLGDFIDMPMRTYSSGMFSRLAFSVSVHMEPDILIIDEALSAGDAKFKERAGQKMSELMGTAGTMLLVSHALGTIQELSDEVIWLHKGRLIKRGEPKEICDAYLEFLKVGDDSIVMEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIT2</accession>
    <name>A0A1Q2CIT2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2-oxoglutarate ferredoxin oxidoreductase subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_02720</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02720"/>
    <dbReference type="EnsemblBacteria" id="AQP45983">
        <property type="protein sequence ID" value="AQP45983"/>
        <property type="gene ID" value="RPIT_02720"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02720"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016903">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022367">
        <property type="entry name" value="2-oxoacid/accept_OxRdtase_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03710">
        <property type="entry name" value="OAFO_sf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POR" evidence="2">
        <location>
            <begin position="23"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="POR_N" evidence="3">
        <location>
            <begin position="255"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="628" mass="67619" checksum="3E9CC900D100CD3D" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIT9</accession>
    <name>A0A1Q2CIT9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_05030</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05030"/>
    <dbReference type="EnsemblBacteria" id="AQP46027">
        <property type="protein sequence ID" value="AQP46027"/>
        <property type="gene ID" value="RPIT_05030"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05030"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="43"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP46027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="248" mass="27536" checksum="490F45FDE626ED7F" modified="2017-04-12" version="1">MLITSLKTRLEVTDIPPVYFPEQPRVENYLEVWETSVSPASALLATAVIAVGATLLVLLVATPAAYYVARFRFPGRLVFLFLVLCTQMLQPTVLAVGLFQQFRDWSGYSIWGALILINGAFNLSFAIWIMQAFFASVPKEVDEAALIDGLGRLQTMFRISLPLVWPGIVTAIVFVFVNSWNEYAAALMLVSNPDLQPLTVAMPRYLSLYIQDWQYLFTVALIAIVPVIVLFALIEKRLIGGLTAGSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIY8</accession>
    <name>A0A1Q2CIY8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_07990</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07990"/>
    <dbReference type="EnsemblBacteria" id="AQP46081">
        <property type="protein sequence ID" value="AQP46081"/>
        <property type="gene ID" value="RPIT_07990"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07990"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012961">
        <property type="entry name" value="Ski2_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08148">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01142">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="20"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="307"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP46081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="911" mass="100452" checksum="2CF22AB97D71A140" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIZ7</accession>
    <name>A0A1Q2CIZ7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chromosome partitioning ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_08050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08050"/>
    <dbReference type="EnsemblBacteria" id="AQP46082">
        <property type="protein sequence ID" value="AQP46082"/>
        <property type="gene ID" value="RPIT_08050"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08050"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="284" mass="30903" checksum="DA01006606F3D6C3" modified="2017-04-12" version="1">MVDTGVIGPTGRPLPEFPEPQPPGPGKRRAVIVSMCNQKGGVGKTTTTINLGAALAETGRKVLLVDFDPQGSLSVGLGVNPHKLDRSIYNLLLSREYTPHDVITESTVDGLDILPSNIDLSAAEVQLVSEVAREQTLHRVLSKLRGDYDFILIDCAPSLGLLTINALTASDYVIMPLECEFFALRGIALLTDTISKVQDRLNPELQVLGILGTMYDARTLHAREVLERVVQAFGDDVFHTVIRRTIKFPETTVAGEPITTYASASPGADAYRQLAREVLLRCQQ</sequence>
</entry>
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    <accession>A0A1Q2CJ00</accession>
    <name>A0A1Q2CJ00_9ACTN</name>
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        <submittedName>
            <fullName evidence="6">Iron transporter permease</fullName>
        </submittedName>
    </protein>
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        <name evidence="6" type="ORF">RPIT_06400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
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        <property type="protein sequence ID" value="AQP46053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06400"/>
    <dbReference type="EnsemblBacteria" id="AQP46053">
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        <property type="gene ID" value="RPIT_06400"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="MetI-like"/>
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        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="4" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
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            <end position="92"/>
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    </feature>
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            <end position="128"/>
        </location>
    </feature>
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            <end position="171"/>
        </location>
    </feature>
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        <location>
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            <end position="214"/>
        </location>
    </feature>
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            <end position="267"/>
        </location>
    </feature>
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    </feature>
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            <end position="376"/>
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        <location>
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            <end position="442"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="4">
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            <end position="513"/>
        </location>
    </feature>
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            <begin position="533"/>
            <end position="554"/>
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            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="350"/>
            <end position="554"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP46053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="572" mass="60706" checksum="441FE910C3FBD8AD" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ38</accession>
    <name>A0A1Q2CJ38_9ACTN</name>
    <protein>
        <submittedName>
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    </protein>
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    </gene>
    <organism evidence="2 3">
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP46093">
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        <property type="gene ID" value="RPIT_08580"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08580"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011138">
        <property type="entry name" value="Cytochrome_b-558"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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            <end position="27"/>
        </location>
    </feature>
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        <location>
            <begin position="64"/>
            <end position="93"/>
        </location>
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            <begin position="114"/>
            <end position="139"/>
        </location>
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            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="228" mass="25336" checksum="6D94161AC50CA789" modified="2017-04-12" version="1">MRTTVVKKVIMAVTGLIMIAFLLMHMYGNLKMFLGPEAFDHYAHWLKGTTDDGGLLYPILPAGWFIWIFRFALVAAVILHIWSAATLSAKTLANRGDKYQVTKRKAQTYSARTMRWGGIIIAAFIIFHLLQFTIVPGSLGTGGSPEGEPHRMVVAGFQQWWMVLIYAICMVLITMHIRHGFWSAFATLGGNMSAKSFRILNVLALIVAVALFVGFMVMPLAVLFGVIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ47</accession>
    <name>A0A1Q2CJ47_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
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    </dbReference>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="5"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="117" mass="13011" checksum="75D379A5895C44F3" modified="2017-04-12" version="1">MVATCPSRTSLAKIANKWTAMIVIALEDGPLRYKAILRAVDGISGKVLAETLRDLQRDGIVTRTAYDVMPPRVDYELTALGQTLHEPLSALGRWAEEHVQEVMKARESYDDRLDSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ58</accession>
    <name>A0A1Q2CJ58_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13845"/>
    <dbReference type="EnsemblBacteria" id="AQP46178">
        <property type="protein sequence ID" value="AQP46178"/>
        <property type="gene ID" value="RPIT_13845"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13845"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="92"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="179" mass="19868" checksum="974B948D8EFFB11B" modified="2017-04-12" version="1">MDEDGARVFFGSRHSVRNFDPDNVPTEGELRSIVELARNTPSVCNRQGFRVHMYRSREDIDAILKIQNGATGFAHVVPAVGVVTARRALFVGPDERNQRWVDGGLFAMTLVWAAHARGFATCMLNWSLPSVSSARLRKVADIPEGEDIVVVIAFGHAKEGARVARSQKRSIDDLAWFHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJC7</accession>
    <name>A0A1Q2CJC7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta-N-acetylhexosaminidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_11825</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11825"/>
    <dbReference type="EnsemblBacteria" id="AQP46145">
        <property type="protein sequence ID" value="AQP46145"/>
        <property type="gene ID" value="RPIT_11825"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11825"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="SSF52279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_3" evidence="4">
        <location>
            <begin position="34"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_3_C" evidence="5">
        <location>
            <begin position="422"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP46145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="585" mass="61231" checksum="E578DC5A9239A628" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBD9</accession>
    <name>A0A1Q2CBD9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized SAM-binding protein YcdF, DUF218 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00095</name>
        <name evidence="4" type="ORF">SAMN05428934_10926</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00095"/>
    <dbReference type="EnsemblBacteria" id="AQP43419">
        <property type="protein sequence ID" value="AQP43419"/>
        <property type="gene ID" value="RPIT_00095"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05053">
        <property type="protein sequence ID" value="SDZ05053"/>
        <property type="gene ID" value="SAMN05428934_10926"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00095"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06259">
        <property type="entry name" value="YdcF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003848">
        <property type="entry name" value="DUF218"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02698">
        <property type="entry name" value="DUF218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544389" evidence="1">
        <location>
            <begin position="33"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="DUF218" evidence="2">
        <location>
            <begin position="46"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ05053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="204" mass="22769" checksum="CBEE3A917A344C45" modified="2017-04-12" version="1">MSRSHRAAVVACLGGAGALALLPDLAHRWASAQSYGDRATEGGTEAILVLGCPSRDDGSLHPLQRWRCGIAARTMNPRVHRVVFTGRTGDREVTEAAVMAGYAQTLGIPDHVIVLEEEARSTWENLQYSAPLVEEFDVVRIVSDPMHGWRARQFLARQRPDLAAKLAPARDHRWLERPVLKTGTFVYEVIARYRERRAPRLPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBL7</accession>
    <name>A0A1Q2CBL7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">L-threonine 3-dehydrogenase</fullName>
            <shortName evidence="6">TDH</shortName>
            <ecNumber evidence="6">1.1.1.103</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tdh</name>
        <name evidence="8" type="ORF">RPIT_00600</name>
        <name evidence="9" type="ORF">SAMN05428934_10573</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-threonine + NAD(+) = (2S)-2-amino-3-oxobutanoate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:13161"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78948"/>
            <dbReference type="EC" id="1.1.1.103"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid degradation; L-threonine degradation via oxydo-reductase pathway; glycine from L-threonine: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.103" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY85362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00600"/>
    <dbReference type="EnsemblBacteria" id="AQP43499">
        <property type="protein sequence ID" value="AQP43499"/>
        <property type="gene ID" value="RPIT_00600"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY85362">
        <property type="protein sequence ID" value="SDY85362"/>
        <property type="gene ID" value="SAMN05428934_10573"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00600"/>
    <dbReference type="UniPathway" id="UPA00046">
        <property type="reaction ID" value="UER00505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008743">
        <property type="term" value="F:L-threonine 3-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019518">
        <property type="term" value="P:L-threonine catabolic process to glycine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00627">
        <property type="entry name" value="Thr_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004627">
        <property type="entry name" value="L-Threonine_3-DHase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="7">
        <location>
            <begin position="10"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="262"/>
            <end position="264"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="286"/>
            <end position="287"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom" evidence="6">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP43499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY85362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="341" mass="36521" checksum="7073B594F5D80484" modified="2017-04-12" version="1">MKALVKTGPGPGLDLIDVPEPVVGPNEVLIKVQRTGICGTDVHIERWDGWAERTVATPRIVGHEFCGTIVELGSSVTDLEVGQFVSGEGHYVCGRCRACLAGKRHLCGNTRGIGYHVDGAFAEYFAMPAGNVWVHQPGLDPDVAAIFDPFGNAVHTALQFPALAEDVLVTGAGPIGIMAALVAQFQGARHVVVSDISDERLELARGLGLQHTVNPGRDSLSELYRRIDMKEGFDIGLEMSGSPAALTSMIDHMVHGGRIALLGTPTREVPLDLAKVIFSMLTLQGVTGRQIFETWYAMSSLLSSGLDISGVITHRFDHTDFAEAFAVAADGRSGKVILNWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBM0</accession>
    <name>A0A1Q2CBM0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nucleotide sugar dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_00605</name>
        <name evidence="7" type="ORF">SAMN05428934_10574</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
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            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY85385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00605"/>
    <dbReference type="EnsemblBacteria" id="AQP43500">
        <property type="protein sequence ID" value="AQP43500"/>
        <property type="gene ID" value="RPIT_00605"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY85385">
        <property type="protein sequence ID" value="SDY85385"/>
        <property type="gene ID" value="SAMN05428934_10574"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR028359">
        <property type="entry name" value="UDP_ManNAc/GlcNAc_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
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    </dbReference>
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        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500136">
        <property type="entry name" value="UDP_ManNAc_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
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    <keyword evidence="4" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544403" evidence="4">
        <location>
            <begin position="23"/>
            <end position="430"/>
        </location>
    </feature>
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        <location>
            <begin position="322"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY85385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="430" mass="46226" checksum="3E0E90026A923E90" modified="2017-04-12" version="1">MKIVVVALGKIGLPLAVQFADAGHDVVGTDVNSALVETINAGKEPFPGEAQLQEKLSRLVPAGKLRASTDTTAAVREADAVVVVVPLMVDSDGAPDFRWMDDATRAIAAGLKPGTLVSYETTLPVGTTRNRWKPMLEEGSGLTEGDDFHLVFSPERVLTGRVFADLRKYPKLIGALTEQGAARATAFYQAVLTFDERRDLVRPNGVWDLGSAEAAEMAKLAETTYRDVNIGLANEFARFASENGIDVYQVIEASNSQPYSHIHRPGIAVGGHCIPVYPKLYLWTDPHASIVRTARASNAAMPAYAVELADQAARGLTGKRVAVLGASYRGGVKETALSGVFPVVAALFERGAHVGVHDPLYTDEELARLGFSPYHLGEEVDVVILHTDHAAYRELSSSDFPGARVVVDGRRSLDPDRFTDVNLVVLGKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBN8</accession>
    <name>A0A1Q2CBN8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoglycolate phosphatase/pyrophosphatase PpaX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00700</name>
        <name evidence="2" type="ORF">SAMN05428934_10593</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY85896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00700"/>
    <dbReference type="EnsemblBacteria" id="AQP43518">
        <property type="protein sequence ID" value="AQP43518"/>
        <property type="gene ID" value="RPIT_00700"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY85896">
        <property type="protein sequence ID" value="SDY85896"/>
        <property type="gene ID" value="SAMN05428934_10593"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00700"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY85896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="221" mass="23374" checksum="F763EC60A3BCFA1D" modified="2017-04-12" version="1">MSVKAALFDLDGTLADTVPLIAEHMSASLNAHGIACVPRDVYPLIGRPILDAMGELHDFADLAHRDTVIDEYRAALHLAVNEVGPGLVLPGVREMLADLRDAGFRIGVVTAKGRLAAEHLLTITELSHLVDVLVTTDDVERGKPHPDSALKALEHLGAEPGETWYVGDASSDVAMAHAAGMPALGITTGAATRDELAEAEYVVDTAEEVTALLLGPSRLHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBR6</accession>
    <name>A0A1Q2CBR6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Patatin-like phospholipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_00860</name>
        <name evidence="6" type="ORF">SAMN05428934_105125</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00860"/>
    <dbReference type="EnsemblBacteria" id="AQP43547">
        <property type="protein sequence ID" value="AQP43547"/>
        <property type="gene ID" value="RPIT_00860"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86747">
        <property type="protein sequence ID" value="SDY86747"/>
        <property type="gene ID" value="SAMN05428934_105125"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00860"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="4">
        <location>
            <begin position="17"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="47"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="348"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY86747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="599" mass="63867" checksum="380734BE56AD8471" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBT1</accession>
    <name>A0A1Q2CBT1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TetR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_00935</name>
        <name evidence="8" type="ORF">SAMN05428934_105139</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43561">
        <property type="protein sequence ID" value="AQP43561"/>
        <property type="gene ID" value="RPIT_00935"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87131">
        <property type="protein sequence ID" value="SDY87131"/>
        <property type="gene ID" value="SAMN05428934_105139"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00935"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003012">
        <property type="entry name" value="Tet_transcr_reg_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00400">
        <property type="entry name" value="TETREPRESSOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="6">
        <location>
            <begin position="14"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="5">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY87131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="224" mass="24697" checksum="2390832FC3236BD3" modified="2017-04-12" version="1">MPARREGQIGSDKGLSKQRVVEAAVRLADREGVHGLSMRRLADALGAGAMSLYHYVANKEELLDAMIDVVFEEIELPPEDTDWQSAMRQRATSARRVLARHRWAIGLMESRTSPGPANLRHREAVTACLRRAGFTVSMATHANWLLDSYVYGHALQEASLPFDTPDEFADMAEDVFLPQLPVDEFPYLNESAAALIAAGYDPADEFSFGLDLVLAALEPLRVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBZ7</accession>
    <name>A0A1Q2CBZ7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01395</name>
        <name evidence="3" type="ORF">SAMN05428934_10827</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01395"/>
    <dbReference type="EnsemblBacteria" id="AQP43634">
        <property type="protein sequence ID" value="AQP43634"/>
        <property type="gene ID" value="RPIT_01395"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01424">
        <property type="protein sequence ID" value="SDZ01424"/>
        <property type="gene ID" value="SAMN05428934_10827"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01395"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="32"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ01424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="247" mass="27546" checksum="E6C9A0C34913BE82" modified="2017-04-12" version="1">MSRNALPAEALDWLTVWHGARMLALVGDTALPRRLSAAGHTVVAITDDAATAAKLSHVDRVTPLLARPEAVPTDPIQFEVVYCHQRLHHYDLDAALPQLARVLRPGGCLSASYLIRDDSVPWVRRLAALLRRFDPMAMKGDYGHESLKALDNSKYFPEVDQRAFRVWQTVTRDDLAALVRAQPLARNLDEKQLAQLLGQVGELYDGAVRPGESLRLPFQLLCWRAWVSHEELTGPVHFPDSGLNIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC13</accession>
    <name>A0A1Q2CC13_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Negative transcriptional regulator, PaiB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_01470</name>
        <name evidence="2" type="ORF">SAMN05428934_10842</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01470"/>
    <dbReference type="EnsemblBacteria" id="AQP43646">
        <property type="protein sequence ID" value="AQP43646"/>
        <property type="gene ID" value="RPIT_01470"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01740">
        <property type="protein sequence ID" value="SDZ01740"/>
        <property type="gene ID" value="SAMN05428934_10842"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01470"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007396">
        <property type="entry name" value="TR_PAI2-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35802">
        <property type="entry name" value="PTHR35802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04299">
        <property type="entry name" value="FMN_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010372">
        <property type="entry name" value="PaiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ01740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="237" mass="26130" checksum="091347850842B00B" modified="2017-04-12" version="1">MEPQGPESYVYLPASQSEADAAACRELLEQVGAGLWITEGPGVPTATLLPTLWSGDRLISHASAANLQFPPGTDRVACRVVVQGPHTYVSPRWYPSVQPGTARGRATGRAVGTWDYEQVQFAGWLRTHTDPRRLREEVRAHAEWFDAQRMADSTVGPSDAQRGPWRLDEAPREFIEAMLRGIVGLELEITDVVGRFKLSQNRTQGDRDGVATGLRERGRDQDLAIADAVDRATPLYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC14</accession>
    <name>A0A1Q2CC14_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Maltooligosyl trehalose hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01440</name>
        <name evidence="4" type="ORF">SAMN05428934_10836</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shaker potassium channel beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01440"/>
    <dbReference type="EnsemblBacteria" id="AQP43642">
        <property type="protein sequence ID" value="AQP43642"/>
        <property type="gene ID" value="RPIT_01440"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01624">
        <property type="protein sequence ID" value="SDZ01624"/>
        <property type="gene ID" value="SAMN05428934_10836"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01440"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005399">
        <property type="entry name" value="K_chnl_volt-dep_bsu_KCNAB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150">
        <property type="entry name" value="PTHR43150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="2">
        <location>
            <begin position="28"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ01624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="349" mass="38311" checksum="8F22C683D3649885" modified="2017-04-12" version="1">MTYIAAEDRYESMPYRRLGTSGLKLPAISLGLWHNFGDDFSIQNQREILRHAFDRGVTHFDLANNYGPPYGSTETNFGRIFADDFRPYRNELVISSKAGWDMWPGPYGFGGSRKYLLSSLDDSLQRMGLDYVDIFYHHRPDPDTPIEETMAALDQAVRSGKALYAGISSYSATLTLQAQKIARDLGTPLVIHQPSYSVLNRWIEDGEPNVLQACEQAGMGIIAFSPLAQGMLTSKYLDGVPENSRAAQGKSLDADLLSDENIAHLRALNDIAGQRGQSLAQMAIAWALRDQGGLSVTSVLLGASSVKQLDDNLGALDNLDFTDDELSRIDEHGGVEGVNLWQGATDSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC16</accession>
    <name>A0A1Q2CC16_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01425</name>
        <name evidence="3" type="ORF">SAMN05428934_10833</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43640">
        <property type="protein sequence ID" value="AQP43640"/>
        <property type="gene ID" value="RPIT_01425"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01557">
        <property type="protein sequence ID" value="SDZ01557"/>
        <property type="gene ID" value="SAMN05428934_10833"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01425"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025338">
        <property type="entry name" value="DUF4244"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14029">
        <property type="entry name" value="DUF4244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ01557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="74" mass="8143" checksum="50A4101E00C76CB8" modified="2017-04-12" version="1">MHHLVPLAHRARAAQLSTRLLAQRGLTTVEYAIGLLGAATAALLLLRIFNDNRLFETLFNNVISIFARMVKGNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC57</accession>
    <name>A0A1Q2CC57_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-directed RNA polymerase specialized sigma subunit, sigma24 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_01730</name>
        <name evidence="5" type="ORF">SAMN05428934_10894</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01730"/>
    <dbReference type="EnsemblBacteria" id="AQP43686">
        <property type="protein sequence ID" value="AQP43686"/>
        <property type="gene ID" value="RPIT_01730"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02716">
        <property type="protein sequence ID" value="SDZ02716"/>
        <property type="gene ID" value="SAMN05428934_10894"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01730"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019606">
        <property type="entry name" value="GerMN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10646">
        <property type="entry name" value="Germane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0564">Palmitate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Germane" evidence="3">
        <location>
            <begin position="257"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ02716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="483" mass="51376" checksum="3CC61B987515A170" modified="2017-04-12" version="1">MAGEEERDWLLQLHEEHGAMLHRLAVLLGAADESERIVRSAFLALYRRGRRVIDPADRVEFLHEHVVHLARAVRGSQGSIELGSVPDSRQDEILRSIGESPDRAAELLVVSHYLGVFGPELAGIMRMSVRSCNQKLEQSLEAVRDRVGDPTPGILPGVIESLSQEVTDALRSAARQVPTPEADTLAKDVAELDSARNGLGPRIIGVLTLGAIAAGLLLAAVTRPTVAAPELPAVSRQALPPSPVATRSLPALVRDVPLYFIGQDGKLYREQRNLPASDNLLSSALDALLTLVPRDPDYASAWSGGQVHSAELAGETLTVDLSADAYEGFTSPALAQQARDQAVYTASELIGNPNLRVVFLSDAGAPPADFAAAEGYTRRGLDPMPAVWITNPRNGEQSAPGAHVFVGTVKADVGEPIVTITEIASGRVIAEVSAQTSLSVNSDGWRVWSVSINLDPGSYDIKAAVTTGTPPVTVSENKSIRIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC61</accession>
    <name>A0A1Q2CC61_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphate-binding protein PstS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_01770</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Part of the ABC transporter complex PstSACB involved in phosphate import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PstS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01770"/>
    <dbReference type="EnsemblBacteria" id="AQP43694">
        <property type="protein sequence ID" value="AQP43694"/>
        <property type="gene ID" value="RPIT_01770"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01770"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042301">
        <property type="term" value="F:phosphate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005673">
        <property type="entry name" value="ABC_phos-bd_PstS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002756">
        <property type="entry name" value="PstS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00975">
        <property type="entry name" value="3a0107s03"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010195396" description="Phosphate-binding protein PstS" evidence="5">
        <location>
            <begin position="25"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="6">
        <location>
            <begin position="49"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="375" mass="38274" checksum="8C9ADF5DFC4A2F7F" modified="2017-04-12" version="1">MTRMKIRLTAALGLSAALMLSACAANESTAPTADTPAATTSAAGASDAPAQEPISGTISGIGASAQEVAQQTWIAGFQTANEAVTVNYAAEGSGAGREAFIGGGADFAGSDRAFKIDELEENSFGKCAADSKAINLPVYISPIAVIFNVEGVEELNLDAATLAGIFKGDITNWNDQAIAATNEGVTLPDLTITAVHRSDTSGTTENFTDYLASAAPDVWDAEKSGDWPYQTGEGAGQTQGVVAAVSGGVGAIGYVDASQAEQFSVAKLGKDGSFHGPTTESAAAIVENSPVEEGRADNDMAIALDREAEGYPIVLVSYLITCQDYEDDAVADLVKSYASYIVSDEGQSAAAERAGSAPLSASLSETVQAAIDSIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC89</accession>
    <name>A0A1Q2CC89_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_01880</name>
        <name evidence="2" type="ORF">SAMN05428934_108124</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ03321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43710">
        <property type="protein sequence ID" value="AQP43710"/>
        <property type="gene ID" value="RPIT_01880"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ03321">
        <property type="protein sequence ID" value="SDZ03321"/>
        <property type="gene ID" value="SAMN05428934_108124"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01880"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ03321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="252" mass="26874" checksum="6EA9D99F04ACE97E" modified="2017-04-12" version="1">MAQKGPLALRLWNFKKAFIEDDTPVDDLSFLSRHRDTLRELVITGDEEMDVAEINQLRALERLNINAPGGANAVLRLAGMPSLRQLSILDRGPEGRRLIVDFGGATEIRQVLLAAPDESEVAAVAALPRLADATLEGAGAFPARFASLELTDLTVTGVTSWPASVTGIERVVSLEVAESRGLADLSLFADASPLRFLTLFDLPGLRSLRGVRFADDAEIDIQGCPDLVDLGELDPGRAVGGAVTGSPRLGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCF9</accession>
    <name>A0A1Q2CCF9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FtsX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_02360</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02360"/>
    <dbReference type="EnsemblBacteria" id="AQP43802">
        <property type="protein sequence ID" value="AQP43802"/>
        <property type="gene ID" value="RPIT_02360"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02360"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="492"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="547"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="590"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="524"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP43802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="628" mass="65060" checksum="AA5D14346AF072C1" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCH6</accession>
    <name>A0A1Q2CCH6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peroxiredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_02450</name>
        <name evidence="4" type="ORF">SAMN05428934_10188</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY24948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02450"/>
    <dbReference type="EnsemblBacteria" id="AQP43819">
        <property type="protein sequence ID" value="AQP43819"/>
        <property type="gene ID" value="RPIT_02450"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY24948">
        <property type="protein sequence ID" value="SDY24948"/>
        <property type="gene ID" value="SAMN05428934_10188"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02450"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Redoxin"/>
    </dbReference>
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        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="52"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY24948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="186" mass="19780" checksum="60F8414EA2A0C564" modified="2017-04-12" version="1">MRDPGGLLRGRLVGVLGLVLLTALVLGAIHLVRGSDATAASDAAEGVPGDGPKVGASAPDFRGLDLDGVPVQLEDYAGKPLWLLFQATWCSICRAELPDVEEASDRIDVVAFYMREDRDLVTDYAERMKLTIRSVPDPIGEISLTYLATSVPTHFFVDADGVIRAVHKGALSPAEIDEKLALVGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCJ7</accession>
    <name>A0A1Q2CCJ7_9ACTN</name>
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        <submittedName>
            <fullName evidence="9">Sodium:proton antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_02475</name>
        <name evidence="10" type="ORF">SAMN05428934_10193</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY25029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43821">
        <property type="protein sequence ID" value="AQP43821"/>
        <property type="gene ID" value="RPIT_02475"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY25029">
        <property type="protein sequence ID" value="SDY25029"/>
        <property type="gene ID" value="SAMN05428934_10193"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02475"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018461">
        <property type="entry name" value="Na/H_Antiport_NhaC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032813">
        <property type="entry name" value="Na_H_antiport_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13726">
        <property type="entry name" value="Na_H_antiport_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03553">
        <property type="entry name" value="Na_H_antiporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
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    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <begin position="150"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="448"/>
        </location>
    </feature>
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        <location>
            <begin position="2"/>
            <end position="87"/>
        </location>
    </feature>
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        <location>
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            <end position="443"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP43821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY25029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="449" mass="46453" checksum="97DF648DBE81531D" modified="2017-04-12" version="1">MNAVVVSVIVMLALSVARVHVVLALFLGALTGGLLAGLGLEATMVAFQDGLAGGAKIALSYALLGAFAMAVAHSGLPQLLANWLITRLDADDMTTSQKVRAWAKWGMIGGILAMAVMSQNLIPVHIAFIPLLIPPLLVIMSRLRLDRRAMACVLTFGLVTTYMFLPIGFGKIFLTDILYGNIISSGLDVSDVPVMSAMGIPALGMLIGLIVALTVTYRRPRDYNPDAAIDTDAPTVIRTKNIVIALIAIVASFTIQTWLTLIDSQADSLLVGALAGLCLFIITGAVKWTDADAVFTGGMRMMALIGLIMIAAQGFAAVMQATGQIAPLVEGVAGAFAGNRAVGALAMLFVGLLVTMGIGSSFSTLPIIAAIYVPLCAALGFSPVATVSIIGTAGALGDAGSPASDSTLGPTAGLNADGQHDHMRDTVIPTFLHFNLPLLAAGWVAAMVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCQ1</accession>
    <name>A0A1Q2CCQ1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Membrane protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Ribonuclease BN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_02710</name>
        <name evidence="6" type="ORF">SAMN05428934_101142</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY26542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02710"/>
    <dbReference type="EnsemblBacteria" id="AQP43860">
        <property type="protein sequence ID" value="AQP43860"/>
        <property type="gene ID" value="RPIT_02710"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY26542">
        <property type="protein sequence ID" value="SDY26542"/>
        <property type="gene ID" value="SAMN05428934_101142"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02710"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017039">
        <property type="entry name" value="Virul_fac_BrkB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30213">
        <property type="entry name" value="PTHR30213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03631">
        <property type="entry name" value="Virul_fac_BrkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035875">
        <property type="entry name" value="RNase_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00765">
        <property type="entry name" value="yihY_not_rbn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="232"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY26542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="356" mass="38458" checksum="55BF875B6CA78A30" modified="2017-04-12" version="1">MSTTSTPHPEHSSKPDSPTDIKPPSWKFVFKNAAREFGDDGLSDAAAGLTYYTVLSLFPAIIALVSILSLFGQSGDLLRNLITDLQDRGAIPVDALDVIMPVMESLLETPAPGIGLILGLLVAMWTASNYVKAFSRAMNRIYEIPEGRGFVKFNASMYALTAGMLALLALVLVLITVSGPLAESIGSLIGLGETALTVFNYAKWPILLVIVILIVSILYWGTPNVKQPKFRWLTIGAGIAIIGTILASLAFAFYVSNFGSYDETYGTLAGVIIFLFWVNIINSVLLFGAEIDAELERGRQLQGGIAAEKEIQLPMRDDKAAIKKQKKAREAVAEARELRLTAGASSDPDEKDESKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCR4</accession>
    <name>A0A1Q2CCR4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucose-1-phosphate thymidylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02555</name>
        <name evidence="3" type="ORF">SAMN05428934_101111</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY25580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02555"/>
    <dbReference type="EnsemblBacteria" id="AQP43835">
        <property type="protein sequence ID" value="AQP43835"/>
        <property type="gene ID" value="RPIT_02555"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY25580">
        <property type="protein sequence ID" value="SDY25580"/>
        <property type="gene ID" value="SAMN05428934_101111"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02555"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="42"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY25580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="272" mass="29259" checksum="3304970D555A708F" modified="2017-04-12" version="1">MTYEAPHKAVILARGLGSRMRKEAEGVALNDEQSKAAEAGVKAMISVGRPFLDHVITALADANFTDVCLVIGPEHDMIRDYYDTVDKQRVTISYAVQEEPLGTANAVLAAEEFAGDDRVLVINSDNYYPAEALESLATVPGSALVGFTREGMLTKSNIAPERLAAFALATADEQGNLAELVEKPDQDAIERLGQDAVISMNCWLCSPAIFDAARAIPKSARGEYEITDAVRRAIDDGDPYFVVKADVGVLDLSNRGDIASVVEALGDREARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCV0</accession>
    <name>A0A1Q2CCV0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplN</name>
        <name evidence="6" type="ORF">RPIT_03140</name>
        <name evidence="7" type="ORF">SAMN05428934_101229</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03140"/>
    <dbReference type="EnsemblBacteria" id="AQP43934">
        <property type="protein sequence ID" value="AQP43934"/>
        <property type="gene ID" value="RPIT_03140"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29165">
        <property type="protein sequence ID" value="SDY29165"/>
        <property type="gene ID" value="SAMN05428934_101229"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03140"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_L14_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_L14P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005745">
        <property type="entry name" value="Ribosomal_L14P_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_L14P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="PTHR11761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="SSF50193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01067">
        <property type="entry name" value="rplN_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY29165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="122" mass="13527" checksum="8460464F6C1D4BF2" modified="2017-04-12" version="1">MIQQESRLKVADNTGAKEILCIRVLGGSKRRYAYLGDTIVATVKDAIPGGNVKKGDVVKAVIVRTKKERRRADGSYIKFDENAAVILKTDGEPRGTRIFGPVARELREKKFMRIVSLAPEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCW0</accession>
    <name>A0A1Q2CCW0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplE</name>
        <name evidence="9" type="ORF">RPIT_03150</name>
        <name evidence="10" type="ORF">SAMN05428934_101231</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03150"/>
    <dbReference type="EnsemblBacteria" id="AQP43936">
        <property type="protein sequence ID" value="AQP43936"/>
        <property type="gene ID" value="RPIT_03150"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29265">
        <property type="protein sequence ID" value="SDY29265"/>
        <property type="gene ID" value="SAMN05428934_101231"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03150"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01333_B">
        <property type="entry name" value="Ribosomal_L5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_L5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020930">
        <property type="entry name" value="Ribosomal_L5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_L5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020929">
        <property type="entry name" value="Ribosomal_L5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_L5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_L5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="PTHR11994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="SSF55282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00358">
        <property type="entry name" value="RIBOSOMAL_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L5" evidence="7">
        <location>
            <begin position="33"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L5_C" evidence="8">
        <location>
            <begin position="93"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP43936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY29265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="208" mass="23428" checksum="BF6DC1CA12DF7B8D" modified="2017-04-12" version="1">MTDTATTTTMPRLKAKYRETIVPALQEEFSYDNVMQIPGLVKIVVNMGVGEAARDSKIIEGAIKDLTAITGQKPAVTKARKSIAQFKLREGMPIGCHVTLRGDRMWEFADRLLTLALPRIRDFRGLNGRQFDGNGNYTFGLSEQVMFLEIDQDKIDRVRGMDITFVTSADNDEEGRALLKHLGFPFKAVDDPKKQKSKRGPAFYKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCY9</accession>
    <name>A0A1Q2CCY9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 7">50S ribosomal protein L3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplC</name>
        <name evidence="8" type="ORF">RPIT_03040</name>
        <name evidence="9" type="ORF">SAMN05428934_101209</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY28534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03040"/>
    <dbReference type="EnsemblBacteria" id="AQP43915">
        <property type="protein sequence ID" value="AQP43915"/>
        <property type="gene ID" value="RPIT_03040"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY28534">
        <property type="protein sequence ID" value="SDY28534"/>
        <property type="gene ID" value="SAMN05428934_101209"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03040"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01325_B">
        <property type="entry name" value="Ribosomal_L3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_L3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_L3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_L3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="PTHR11229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP43915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY28534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="218" mass="22992" checksum="B06A931BFAABA346" modified="2017-04-12" version="1">MSERIVKGILGTKLGMTQLWDENNKVVPVTVIQAGPCVVTQVRTPEVDGYSAVQLGFGAIKAKKVTKPAAGHFAKADVTPRKHLVELRTADASEFTLGQELTAEVFADGEFVDVTGTSKGKGTAGVMKRHGFHGLRASHGVHRKHRSPGSIGGCATPGRVFKGLRMAGRMGNEKITVQNLKIHAVDVERGLLLVRGAIPGNNGSLVVVRSAAKKGVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD44</accession>
    <name>A0A1Q2CD44_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Glutamine synthetase</fullName>
            <ecNumber evidence="5">6.3.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_03540</name>
        <name evidence="8" type="ORF">SAMN05428934_101309</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16169"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glutamine synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.2" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY31604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03540"/>
    <dbReference type="EnsemblBacteria" id="AQP44000">
        <property type="protein sequence ID" value="AQP44000"/>
        <property type="gene ID" value="RPIT_03540"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY31604">
        <property type="protein sequence ID" value="SDY31604"/>
        <property type="gene ID" value="SAMN05428934_101309"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03540"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008147">
        <property type="entry name" value="Gln_synt_b-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004809">
        <property type="entry name" value="Gln_synth_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027302">
        <property type="entry name" value="Gln_synth_N_conserv_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03951">
        <property type="entry name" value="Gln-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="SSF54368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00653">
        <property type="entry name" value="GlnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00180">
        <property type="entry name" value="GLNA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="6">
        <location>
            <begin position="104"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-AMP-tyrosine" evidence="3">
        <location>
            <position position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR604809-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY31604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="473" mass="52752" checksum="E7B106542949FC13" modified="2017-04-12" version="1">MFNSAEELLAYIRDEGIETVDVRFCDLPGVMQHFTVPASFFGPEVFEDGLSFDGSSITGFQKIHESDMALMPDPTTAYVDPFRKSKTINVNFFVHDPLTKEPYSRDPRNIARKAEAYLASTGIGDSAFFAPEAEFYVFDDIRFETTANSSYYHIDSEAGAWNTGRVEDGGNRGYKVKFKGGYFPVAPVDHFGDLRDDIVRHMGNAGLQVERAHHEVGTAGQAEINWRFNSLLKSADDVMKFKYLVKNTAWEAGKTATFMPKPIFGDNGSGMHVHSSIWNNGEPLFYDEGGYAGLSDMARWYIGGILKHAPALLAFTNPSVNSFHRLVPGFEAPVNLVYSQRNRSACIRIPITGSNPKAKRIEFRCPDPSSNPYLAFAAILLAGLDGIQNRIEPMDPIDKDLYELPPDEHAQVPTVPASLGAVLDELEADQEFLLAGDVFTPDLLETWIELKRAEIQAIAMRPHPHEFELYYAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD63</accession>
    <name>A0A1Q2CD63_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44020">
        <property type="protein sequence ID" value="AQP44020"/>
        <property type="gene ID" value="RPIT_03660"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03660"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="104" mass="11515" checksum="574E3423A26B2974" modified="2017-04-12" version="1">MTAHRDFLVSQTLVESSRGEKAPSGAKWLTAMSPAGRLETPRDDVDLRTQLRLPYRSQCSRRLTAGAEEATHSKRTGRSADRARNVTYVPSSLRRLASGLGMRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDC7</accession>
    <name>A0A1Q2CDC7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_04110</name>
        <name evidence="2" type="ORF">SAMN05428934_101425</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY34823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44097">
        <property type="protein sequence ID" value="AQP44097"/>
        <property type="gene ID" value="RPIT_04110"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY34823">
        <property type="protein sequence ID" value="SDY34823"/>
        <property type="gene ID" value="SAMN05428934_101425"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04110"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY34823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="421" mass="46096" checksum="768C526FA0B8F1C6" modified="2017-04-12" version="1">MSVNSIRGRQREEQRLAAVLGHAEATLDALELDTGKHSHEDFFTRTKLAAETSLLLLATHRAQLGPGMDERVRRIGSRLTAAARSIELLTWVQLRPHILPELSVPHLVLSAVGLPDEDFAAALAHAAQTTSVAPTERLPWKQIERCWQHDLGAPACLPPLAARLEATALAARQDALFATREEVYSFTHALIYHTDFGHRQPGLPRPAGDLVEDAGSALARCLDDDDFDLAAEVLFTWPYLRQSWDATSVFGLRLLRDVDDEVGFLPSMTLSQERFRELDGDAARRYFYAESYHTVFVLGLLTAATLSPGIETCPGSVAAPELAHVAEQVLDLMPAAEHHRQWEQVARDLPSVERGALVPMLGDIAVRRAVRQSDFRRVREIVETVLDSGATAGTATIQGAELVLRLGSSPATRAAATTPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDD0</accession>
    <name>A0A1Q2CDD0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_04320</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04320"/>
    <dbReference type="EnsemblBacteria" id="AQP44133">
        <property type="protein sequence ID" value="AQP44133"/>
        <property type="gene ID" value="RPIT_04320"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04320"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016653">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006784">
        <property type="term" value="P:heme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003780">
        <property type="entry name" value="COX15/CtaA_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02628">
        <property type="entry name" value="COX15-CtaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="313" mass="33751" checksum="7F6D493665F6E06C" modified="2017-04-12" version="1">MEGVHVDVLRKLVDGERALRTWLWISLVCNMGIIVTGAVVRLTGSGLGCPTWPRCTEDSYVPHPSYGIHGVIEFGNRLLTFVLIAAAIGAFVAAWRNRGARSKLWWINLGIGLGIPFQAVIGGFTVWSNLNPFVVALHLLLSVALIVLCVWALRVGYRTEPEPVAPGLRWLVHATFWAAMLSIWVGTIVTGSGPHAGDAKSPRTGFDIEFVARLHGLSAWLVVALSVASLVVLLRSGHRRAARAARLLVITVVLQGAIGYLQYFLGVPVGIVILHMVGLTLLTAAAAWLLVSTTRRTHADQSGADDRTSVHAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDE0</accession>
    <name>A0A1Q2CDE0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metal-sulfur cluster biosynthetic enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_04370</name>
        <name evidence="4" type="ORF">SAMN05428934_101479</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY36373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04370"/>
    <dbReference type="EnsemblBacteria" id="AQP44143">
        <property type="protein sequence ID" value="AQP44143"/>
        <property type="gene ID" value="RPIT_04370"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY36373">
        <property type="protein sequence ID" value="SDY36373"/>
        <property type="gene ID" value="SAMN05428934_101479"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04370"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="2">
        <location>
            <begin position="28"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY36373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="126" mass="13984" checksum="FD6DF0161CB324D2" modified="2017-04-12" version="1">MYTPEQRPSDLVKDDLPDVDSPSAVPSEDEVLEALKDVVDPELMVNVVDLGLVYGVQIDDGANATIDMTLTSPTCPLTDKIEYDTKYVLEGLVNSATINWVWLPPWSLEMITEDGREQLRAVGYNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDH4</accession>
    <name>A0A1Q2CDH4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13 14">UvrABC system protein B</fullName>
            <shortName evidence="13">Protein UvrB</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Excinuclease ABC subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">uvrB</name>
        <name evidence="19" type="ORF">RPIT_04155</name>
        <name evidence="20" type="ORF">SAMN05428934_101435</name>
    </gene>
    <organism evidence="19 21">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 21" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 21">RP1T</strain>
        </source>
    </reference>
    <reference evidence="20 22" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 22">RP1</strain>
        </source>
    </reference>
    <reference evidence="19" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 13">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11 13 14">Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="13">The beta-hairpin motif is involved in DNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13 14">Belongs to the UvrB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY35159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04155"/>
    <dbReference type="EnsemblBacteria" id="AQP44105">
        <property type="protein sequence ID" value="AQP44105"/>
        <property type="gene ID" value="RPIT_04155"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY35159">
        <property type="protein sequence ID" value="SDY35159"/>
        <property type="gene ID" value="SAMN05428934_101435"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04155"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00204">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004807">
        <property type="entry name" value="UvrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024759">
        <property type="entry name" value="UvrB_YAD/RRR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24029">
        <property type="entry name" value="PTHR24029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12344">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00631">
        <property type="entry name" value="uvrb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 13 14" id="KW-0228">DNA excision</keyword>
    <keyword evidence="9 13 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 13 14" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 14" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="17">
        <location>
            <begin position="35"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="18">
        <location>
            <begin position="438"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="16">
        <location>
            <begin position="640"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="636"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Beta-hairpin" evidence="13">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="48"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="AQP44105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="SDY35159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="684" mass="77403" checksum="F14419540DC05118" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDI9</accession>
    <name>A0A1Q2CDI9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription termination/antitermination protein NusA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nusA</name>
        <name evidence="9" type="ORF">RPIT_04575</name>
        <name evidence="10" type="ORF">SAMN05428934_101521</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Participates in both transcription termination and antitermination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NusA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04575"/>
    <dbReference type="EnsemblBacteria" id="AQP44178">
        <property type="protein sequence ID" value="AQP44178"/>
        <property type="gene ID" value="RPIT_04575"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37413">
        <property type="protein sequence ID" value="SDY37413"/>
        <property type="gene ID" value="SAMN05428934_101521"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04575"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1480.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00945_B">
        <property type="entry name" value="NusA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025249">
        <property type="entry name" value="KH_dom_NusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030842">
        <property type="entry name" value="NusA_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036555">
        <property type="entry name" value="NusA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013735">
        <property type="entry name" value="TF_NusA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010213">
        <property type="entry name" value="Tscrpt_termination_fac_NusA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22648">
        <property type="entry name" value="PTHR22648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13184">
        <property type="entry name" value="KH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08529">
        <property type="entry name" value="NusA_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69705">
        <property type="entry name" value="SSF69705"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01953">
        <property type="entry name" value="NusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="5 7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 7" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="S1 motif" evidence="8">
        <location>
            <begin position="112"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY37413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="324" mass="35801" checksum="4E65AAE3CDCF6C8B" modified="2017-04-12" version="1">MDVDLAALRAIERDKEISFDYLIKALEDALLNAYKKTPHALRGVKVEVDRKTGKVSVLAPEFDDDDEVIGFYDDTPDDFGRIAAATARQVIFQRLREAEDDQKFGHFAGSEGDILVGTIQQDRDSKAVRVDLGTLEAIMPLAEQVPGEDYSHGRRLRVYVVAVRREMRGPQVVVSRTHPNLVRKLFALEVPEIASGIVEIMEVAREAGHRTKIAVRSNHADVSAKGAFIGPMGQRVRAVTNELGEEKIDIVDYSDDPARFVAAALSPAKVLSVQILDPDARACRAIVPDYQLSLAIGREGQNARLAARLTGWRIDIQPDTAPQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDL9</accession>
    <name>A0A1Q2CDL9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HTH tetR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_04620</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44187">
        <property type="protein sequence ID" value="AQP44187"/>
        <property type="gene ID" value="RPIT_04620"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04620"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025996">
        <property type="entry name" value="TetR_C_WHG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13305">
        <property type="entry name" value="TetR_C_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="5">
        <location>
            <begin position="9"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="4">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="175" mass="19352" checksum="BD7F48C5377A1AA1" modified="2017-04-12" version="1">MARPKVHDERLAEVLLEQSAVIVAKGGPDALSLRKLTDAVGTSTSAVYSLYGSREALLLAVYERALASFERSAQELPVTDRPMSDLFRMGREYRRWALSNPQLYPVMFMGPAGSGPEQRRALAMPTIDRLIAALRRCIEAGELRDAESIEVMACQLWATVHGHVSLELMGLLTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDS3</accession>
    <name>A0A1Q2CDS3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc transport system substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05075</name>
        <name evidence="4" type="ORF">SAMN05428934_101621</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY39938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05075"/>
    <dbReference type="EnsemblBacteria" id="AQP44263">
        <property type="protein sequence ID" value="AQP44263"/>
        <property type="gene ID" value="RPIT_05075"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY39938">
        <property type="protein sequence ID" value="SDY39938"/>
        <property type="gene ID" value="SAMN05428934_101621"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05075"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006127">
        <property type="entry name" value="ZnuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01297">
        <property type="entry name" value="ZnuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544443" evidence="2">
        <location>
            <begin position="33"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY39938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="324" mass="34170" checksum="B8444D78A93821A6" modified="2017-04-12" version="1">MVLMTSLIRLTAVAAATVLALTACGQGEPSPATDSPSTPGTSVIAAFYPLAWAAEQVLGGDSAVTTLTSPGAEAHDLELSPQQIASLPDADLIIYLEGFQPAVDAAIEQSGATNLLEVGDVVDLLPLPEEGHSHDDEDGHSAEAEDDAHDEDEGHAEHGSDDPHFWQDPMRMALLIDALAERLPVDEATVESAKETLTGLDEAYSTQLANCERREFITTHAAFQYLADRYDLVEIGISGVNPDAEPSPARIAEVHDEAERHGITTIFFETLTSDAVASSIAGDLGLKTAVLDPLEGVTDKSPGTDYPSIMTANLESLVAANECN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDV1</accession>
    <name>A0A1Q2CDV1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cation acetate symporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Cation/acetate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_05115</name>
        <name evidence="9" type="ORF">SAMN05428934_101629</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY40175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05115"/>
    <dbReference type="EnsemblBacteria" id="AQP44271">
        <property type="protein sequence ID" value="AQP44271"/>
        <property type="gene ID" value="RPIT_05115"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY40175">
        <property type="protein sequence ID" value="SDY40175"/>
        <property type="gene ID" value="SAMN05428934_101629"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05115"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="334"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="384"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="408"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="443"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="477"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY40175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="531" mass="55522" checksum="A9E064EFE2EE2903" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDW3</accession>
    <name>A0A1Q2CDW3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Precorrin-6A synthase (Deacetylating)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_05220</name>
        <name evidence="7" type="ORF">SAMN05428934_101650</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY40708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05220"/>
    <dbReference type="EnsemblBacteria" id="AQP44287">
        <property type="protein sequence ID" value="AQP44287"/>
        <property type="gene ID" value="RPIT_05220"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY40708">
        <property type="protein sequence ID" value="SDY40708"/>
        <property type="gene ID" value="SAMN05428934_101650"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05220"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043819">
        <property type="term" value="F:precorrin-6A synthase (deacetylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11643">
        <property type="entry name" value="Precorrin-6A-synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012797">
        <property type="entry name" value="CobF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="5">
        <location>
            <begin position="5"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY40708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="241" mass="26261" checksum="69E7A8404737DA83" modified="2017-04-12" version="1">MARRVFVIGMGPGGFGQLTLDAVDAMNEVDVFLVGDHSDDAPDLVWLRSEVIRRHVARAHRVITVLDPGRDHPPPDDLDDARLATYGQILGGLSDDLTVGFLAWGDPVTYDSILRVVDALRSAHPLEVKVIPGVSAPQVLAAAHQIALDGRAVHITTGPRLLSDYDPGLGDVVVLNDPDLTCRGLAEEFPDLEIFWGAFLGTEDQVLANGPLRQVLPDLVDLRDKLQAHHGWLNDTYLLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDW8</accession>
    <name>A0A1Q2CDW8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperone protein DnaJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dnaJ</name>
        <name evidence="10" type="ORF">RPIT_04970</name>
        <name evidence="11" type="ORF">SAMN05428934_101600</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 2 Zn(2+) ions per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DnaJ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY39390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04970"/>
    <dbReference type="EnsemblBacteria" id="AQP44245">
        <property type="protein sequence ID" value="AQP44245"/>
        <property type="gene ID" value="RPIT_04970"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY39390">
        <property type="protein sequence ID" value="SDY39390"/>
        <property type="gene ID" value="SAMN05428934_101600"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04970"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="SSF57938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 6 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 6 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="4"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="9">
        <location>
            <begin position="129"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="142"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="159"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="185"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="199"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="7">
        <location>
            <begin position="129"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY39390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="385" mass="40914" checksum="B0D4EA89D6EFFF64" modified="2017-04-12" version="1">MSKDYYAILGVDRDATPEAIKKAYRRRAMKVHPDVAQDDDAADQFKELGEAYEVLSDPNKRAIFDRGGDPHQGAGFSGFGGGFAGGFDFTNLVDAMFGAAGSRGPRSRVRQGQDALVRINLALHEAVFGTTKPVKVDTAVVCPKCMGQGGEPGSEPVTCSTCDGAGEVSQIQRSFLGDIRTSQACPTCRGYGTIIPRPCGECSGEGRVRASRTLQVRIPAGVSTGIRIHLESQGEVGPGGGPAGDLYVELNVLAHETFRREGDNLEVVVKLPMTAAALGTTIDVATLESEWDKSDVEDRKVAVEVPAGTQSGTRIALKGRGVPRLRGGGRGDLGVTLLVQTPTKLDDRQRELLRQLAEERDESAPEAVAAKGGRGVFGKLSEWFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDY1</accession>
    <name>A0A1Q2CDY1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase_M23 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_05305</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05305"/>
    <dbReference type="EnsemblBacteria" id="AQP44301">
        <property type="protein sequence ID" value="AQP44301"/>
        <property type="gene ID" value="RPIT_05305"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05305"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013338037" description="Peptidase_M23 domain-containing protein" evidence="3">
        <location>
            <begin position="28"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="4">
        <location>
            <begin position="367"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="300"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="27"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="165"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="471" mass="50064" checksum="B06ACDC6171ED80B" modified="2017-04-12" version="1">MNRIVRGIVAAVAAVSMIGATWSPALADELDDRQLELQQELAQQAAAIEDASAELNSAISAHESARAQLASAETALAAAEVEQRAAEELDAQRAAELADAEKKLEQAKADVAAAKAALDSVNNRINEEILVTTQQNHGFLNLVLIFSDVDTSNLNQRAQLAETLFDSSAQELDELEMRRLALEDAELAATEAEKKAEEARVAAAEQLTAKQEAAAQAEALRVEVARLVELRDAAETAAAQQLLAEQEREAQLRAESEAVEARIQARIEAERKAEESRIAAAKAAAEKAAADKAAADKAAREAAARAAGNSAPKPSTTSKAPAKKPAAAAPAPQAKPVPSSILQRPVNGRLSSRYGMRLHPVLGYRKLHDGTDFAAACGTPLRAAADGVVAERYYNAGYGNRLMIDHGKIGGSYVTTGYNHATHYIVSVGQRVQRGQVIGYVGTTGYSTGCHLHLMVWENGKVVNPMAKWFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDZ3</accession>
    <name>A0A1Q2CDZ3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05400</name>
        <name evidence="3" type="ORF">SAMN05428934_10327</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY65761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05400"/>
    <dbReference type="EnsemblBacteria" id="AQP44317">
        <property type="protein sequence ID" value="AQP44317"/>
        <property type="gene ID" value="RPIT_05400"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY65761">
        <property type="protein sequence ID" value="SDY65761"/>
        <property type="gene ID" value="SAMN05428934_10327"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05400"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POLIIIAc" evidence="1">
        <location>
            <begin position="3"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY65761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="283" mass="30696" checksum="50A1C61CF1F46C7D" modified="2017-04-12" version="1">MRIDLHTHSRVSDGTDTPTSLVMKAFEAGLDVIALTDHDTFGGVMEAQEAGKRIGVKVLCGIEMSTEHNHRPVHLLGYGCDPFDRALNAELAKIRFARTDRLPAMVKALSDEGLEITLDDVMAAANGAPTIGRPHVADALVAKGYVADRDQAFAEWLGEDRPGYVYRYASPLEHAIDLIHAAKGVAVLAHPWGRQGKDALSAPYIESLVQSHGLEGLEVDHEDHDVDTRSLLFEMGARLGLVRTGSSDYHGTGKKGHPLGANLTRPSAYRDLVARIRRRGGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDZ4</accession>
    <name>A0A1Q2CDZ4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05540</name>
        <name evidence="3" type="ORF">SAMN05428934_10355</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY66571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05540"/>
    <dbReference type="EnsemblBacteria" id="AQP44344">
        <property type="protein sequence ID" value="AQP44344"/>
        <property type="gene ID" value="RPIT_05540"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY66571">
        <property type="protein sequence ID" value="SDY66571"/>
        <property type="gene ID" value="SAMN05428934_10355"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05540"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025329">
        <property type="entry name" value="DUF4235"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14019">
        <property type="entry name" value="DUF4235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY66571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="97" mass="10652" checksum="7E9E588F6F1CE5C9" modified="2017-04-12" version="1">MAMTEKVLWKIYAGVVGAVTTLVAQKVVTKVWEASTGDNPPDPNDPDVPLTKALIWATASGLGVGMTQLAMNRFVQRRWVSNFEHRAPGKLVSRFNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE09</accession>
    <name>A0A1Q2CE09_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ACP S-malonyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">[acyl-carrier-protein] S-malonyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05210</name>
        <name evidence="4" type="ORF">SAMN05428934_101648</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY40649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05210"/>
    <dbReference type="EnsemblBacteria" id="AQP44285">
        <property type="protein sequence ID" value="AQP44285"/>
        <property type="gene ID" value="RPIT_05210"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY40649">
        <property type="protein sequence ID" value="SDY40649"/>
        <property type="gene ID" value="SAMN05428934_101648"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05210"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_AT" evidence="2">
        <location>
            <begin position="5"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY40649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="312" mass="32482" checksum="22BF05690AEFAD76" modified="2017-04-12" version="1">MLAIVAPGQGAQTPGFLTAWLQDPESAERVAQMSGVTDLDLAHFGTEADAETIRDTAVAQPLLVAASLVAARALSADLASLADVVAGHSVGELAAMALAGVLHDDDAIKLVRERGQAMAEASALRETSMTAVVAGKPDEVLAAIEEAGLTPANNNGAGQIVAAGTVEQLAALADNPPRRARLVPLSVAGAFHTVHMEPAVERLTRVAEGVASAAPRTRLISNRDGAVVTNGDDALLRMINQVANPVRWDLCMETMTQLGVTGILELTPAGTLTGIAKRNLPGVELFNLDSPDQLDDARAFCRTHSTFHNDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE11</accession>
    <name>A0A1Q2CE11_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_05510</name>
        <name evidence="2" type="ORF">SAMN05428934_10349</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY66406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05510"/>
    <dbReference type="EnsemblBacteria" id="AQP44338">
        <property type="protein sequence ID" value="AQP44338"/>
        <property type="gene ID" value="RPIT_05510"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY66406">
        <property type="protein sequence ID" value="SDY66406"/>
        <property type="gene ID" value="SAMN05428934_10349"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05510"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY66406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="371" mass="39489" checksum="C6FE9FD5893527B9" modified="2017-04-12" version="1">MEFVDPRYDDLALANVMPSIAARLEGGQPTLHLPAARRYVLLLVDGLGWHQLHEYADHAETMASLLPRAQRLTCSVPSTTATSLTSLGCGATPGQHGIVGYSFYEPVVHRVVNALTWEGGPDDVEGFAQMPTVFQRLATTGHASGAVTLGRFAGSALTRLAFTGTSLFPVAAEGDAGQFAGLVTEALGAAEVVYCYERMLDADGHSHGVGSWQWLERLAIVDDLVAHLLDTLPDDVCLLVTGDHGMINVPEASRLIVEDESRLGGYQHLGGEPRFRHVYGEDPRALAWAWESVLGERAHVLRREDAIDAGWFGAQVSGMSAARIGDVVAAMTGDFALMSHGTPGEFSLVGMHGSLTAAEMEVPLLIHGGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE21</accession>
    <name>A0A1Q2CE21_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_05415</name>
        <name evidence="2" type="ORF">SAMN05428934_10330</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY65846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05415"/>
    <dbReference type="EnsemblBacteria" id="AQP44320">
        <property type="protein sequence ID" value="AQP44320"/>
        <property type="gene ID" value="RPIT_05415"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY65846">
        <property type="protein sequence ID" value="SDY65846"/>
        <property type="gene ID" value="SAMN05428934_10330"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05415"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021456">
        <property type="entry name" value="DUF3107"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11305">
        <property type="entry name" value="DUF3107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY65846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="74" mass="7888" checksum="A3D1FD9F2977142A" modified="2017-04-12" version="1">MEVKIGITDVPREVVIETAATADEVASSLHDALQSDGFFELVDEKGRRVLVPARKIGYLDLGSPSARTVGFGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE48</accession>
    <name>A0A1Q2CE48_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05870</name>
        <name evidence="3" type="ORF">SAMN05428934_103122</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44399">
        <property type="protein sequence ID" value="AQP44399"/>
        <property type="gene ID" value="RPIT_05870"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68263">
        <property type="protein sequence ID" value="SDY68263"/>
        <property type="gene ID" value="SAMN05428934_103122"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05870"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY68263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="114" mass="12713" checksum="A4B7F3016EA57EC4" modified="2017-04-12" version="1">MRRAHVVTAEGEREMTPLKGSWEYRRAKFSARQPALAVAGVVVAAILLLAALFLEVTQSVQWVTRAEWFDAVSRWEYTAPVDLPLAANVGITLLGILAAAYCAVNLRHRWLYSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE68</accession>
    <name>A0A1Q2CE68_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Carbohydrate ABC transporter membrane protein 2, CUT1 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_05825</name>
        <name evidence="7" type="ORF">SAMN05428934_103112</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05825"/>
    <dbReference type="EnsemblBacteria" id="AQP44391">
        <property type="protein sequence ID" value="AQP44391"/>
        <property type="gene ID" value="RPIT_05825"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68013">
        <property type="protein sequence ID" value="SDY68013"/>
        <property type="gene ID" value="SAMN05428934_103112"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05825"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="77"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY68013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="281" mass="31306" checksum="60BC8023C284E649" modified="2017-04-12" version="1">MADPSARRRSRGPRYPWAHVLLILGALLMTFPFLWQLLMSVSTNAEIQSVPPQPIPDRLHFSNYAEVFERLPFLNQFGVSVLITVARTAGQVVLCSMAGYAFARMRFPLRNVLFIALLLILMIPSQAYIIPQYGLVQAWGLLETPWAIILPGLFSAFGTFLMRQQFMSLPIELEEAARLDGANPFQVFSRVMLPLATPGIFAVAITTVLYSWNDLLWPLIVTTREESMPLSVGIATLQGQHTTDYAVIMAASVMAMAPIFVLFMLMQRRVIEGLATSGLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE88</accession>
    <name>A0A1Q2CE88_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_06115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06115"/>
    <dbReference type="EnsemblBacteria" id="AQP44439">
        <property type="protein sequence ID" value="AQP44439"/>
        <property type="gene ID" value="RPIT_06115"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06115"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="223" mass="24318" checksum="C8FB4ECE5FE895B7" modified="2017-04-12" version="1">MSTLARPKAVLWDFDGTLVDTEPLWAATEQLMMAERGLAFTADQMKSMHGQSAWLTAEMIATAFGEPHLVADVYDELHRRMATHLRTNDLPWLPGARELLSELHAENVPCAVVTASNNVIVDAARDRLPDNVAFIVTSDDVQRTKPHPEPYLTAMERLGVAGADTVVLEDSVPGTTSGLAAGAVVYAVPTLVKLEPQPRMVISPTGLAETSWADLIQVWKDYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEC0</accession>
    <name>A0A1Q2CEC0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">30S ribosomal protein S13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_06165</name>
        <name evidence="2" type="ORF">SAMN05428934_103178</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY69652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06165"/>
    <dbReference type="EnsemblBacteria" id="AQP44448">
        <property type="protein sequence ID" value="AQP44448"/>
        <property type="gene ID" value="RPIT_06165"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY69652">
        <property type="protein sequence ID" value="SDY69652"/>
        <property type="gene ID" value="SAMN05428934_103178"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06165"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY69652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="103" mass="11474" checksum="D062A7C845205ADD" modified="2017-04-12" version="1">MAIPQLSSAQLEAARSAATEARRQRADLKDRVKSGELSFTDALDKAVDDDSLSRIKVVDLLRAIPRVGITRATEIMENLDIAPNRRIRGLGRHQISRLNELLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CED1</accession>
    <name>A0A1Q2CED1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein adenylyltransferase SelO</fullName>
            <ecNumber evidence="9">2.7.7.n1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">selO</name>
        <name evidence="10" type="ORF">RPIT_06060</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-seryl-[protein] = 3-O-(5'-adenylyl)-L-seryl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:58120"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:15073"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:142516"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-threonyl-[protein] = 3-O-(5'-adenylyl)-L-threonyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:54292"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13847"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:138113"/>
            <dbReference type="EC" id="2.7.7.n1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-tyrosyl-[protein] = diphosphate + O-(5'-adenylyl)-L-tyrosyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:54288"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:13846"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:83624"/>
            <dbReference type="EC" id="2.7.7.n1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SELO family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.n1" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06060"/>
    <dbReference type="EnsemblBacteria" id="AQP44430">
        <property type="protein sequence ID" value="AQP44430"/>
        <property type="gene ID" value="RPIT_06060"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06060"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00692">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003846">
        <property type="entry name" value="SelO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32057">
        <property type="entry name" value="PTHR32057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02696">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="92"/>
            <end position="95"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="127"/>
            <end position="128"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="487" mass="52416" checksum="E5A8CC7E1A4F679E" modified="2017-04-12" version="1">MKLVPPSAIALDRSFARDVPEMGVPWEAQPVPDPRLLVLNQALAVELGWDPEGLRSGDGLRLLLGNVVPEGATPVAQAYAGHQFGGYSPLLGDGRALLLGEIVDDAGQRLDVHLKGSGRTPFARGGDGLAAVGPMLREYVISEAMHALGIPTTRSLAVVATGQTVRREALLPGAVLTRIASSHLRVGSFEYARSTGDIDLLQRLADHAIARHYPNTAEADNPYLELFEAVLSAQASLVAQWMLVGFIHGVMNTDNMTISGETIDYGPCAFMEAFDPATVFSSIDGGGRYAYGRQPMVAQWNLARLAEALLPLVHEDEQQAVALVVERLTAFPGRYAAAWLAGMRAKLGLPDELNDAVASPLIDDLLALLQKDQVDYTSFFRHLAAAARGDDGPARGLFDDATAFDAWLGRWRDLRPQADAMDRVNPVYIPRNHLVEEALAAGTEGNLDPLARLLEAVANPFHERAGLERYAAPAPSTFGPYETFCGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEE0</accession>
    <name>A0A1Q2CEE0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Quinol monooxygenase YgiN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06410</name>
        <name evidence="3" type="ORF">SAMN05428934_103227</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06410"/>
    <dbReference type="EnsemblBacteria" id="AQP44489">
        <property type="protein sequence ID" value="AQP44489"/>
        <property type="gene ID" value="RPIT_06410"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70975">
        <property type="protein sequence ID" value="SDY70975"/>
        <property type="gene ID" value="SAMN05428934_103227"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06410"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="2"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY70975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="101" mass="11493" checksum="850AE50121760DE4" modified="2017-04-12" version="1">MKTLFAEFTALPGHEERVSFLIQGLADKVRQEPGNVVFQPFTREDHPRRWFVFEQYADEAAFEAHINADYGAEFNAELAQHIVEEGSELTWLVEPSSPSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEG2</accession>
    <name>A0A1Q2CEG2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Iron ABC transporter substrate-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Iron(III) transport system substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_06395</name>
        <name evidence="4" type="ORF">SAMN05428934_103224</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06395"/>
    <dbReference type="EnsemblBacteria" id="AQP44487">
        <property type="protein sequence ID" value="AQP44487"/>
        <property type="gene ID" value="RPIT_06395"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70901">
        <property type="protein sequence ID" value="SDY70901"/>
        <property type="gene ID" value="SAMN05428934_103224"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06395"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026045">
        <property type="entry name" value="Ferric-bd"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002825">
        <property type="entry name" value="CfbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544449" evidence="2">
        <location>
            <begin position="26"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY70901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="362" mass="38490" checksum="47636146CA2C8051" modified="2017-04-12" version="1">MTRHRIARALAAGAAATALLFTSCAIDEPDTSPAPAGSGSESVAPEAEDSLVVACGNQEDVCQAWVGAFEEETGIATSYVRLASGEAVARLESAKSNPEFDVWHGGPVDGYNVAAAAGLLEQYDSPAAADIDDEYMDPDGYWGGIYVGVLGFCSNQAVLDSLGIEAPETWDDLLQPELKGQVMMAHPATSGTAFTTLWTQVVLRGGEEEGMDWMRQLHSNILQYTKSGSAPAQSAGRGEVATSIVFSHDCVKYEEQGMTDLVTTIPSDGTGWEIGGVALIKGAQHPNAAKLYYDWALSAEAQEIGPQHQSYQLFTNPNGAPDERMVNLDDVTLVDYDFKAAAEAKEELTARFDAEIAAAPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEG8</accession>
    <name>A0A1Q2CEG8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase_S8 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_06470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06470"/>
    <dbReference type="EnsemblBacteria" id="AQP44498">
        <property type="protein sequence ID" value="AQP44498"/>
        <property type="gene ID" value="RPIT_06470"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06470"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S8" evidence="2">
        <location>
            <begin position="239"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="492" mass="52046" checksum="2BA2FC19A95C556E" modified="2017-04-12" version="1">MPRVLDPLTSDPLPGGRPPRPVGYLGDSILVRGRPGRDDRAAVAVLREAAAQLGWSVEPADPKSVVTERLRADERASSVLEGAWVSDYRIRSADGPPPDAWSVLALARRLHPEAATGLQLNHLLSLQPSYQGMPYYVSMPYYVSMPYYVSMPAASEYSSPGSGGRTPVSLVLPDPALRARTLRRRPVVVVPDTALGSHPWFQDPTTATGEVYAYGFRLGIGGDLPSAAPIPPANPLDGRVRSHAGHGTFIAGLIRQLCPEARIEVIALIDDAGTMPEAVLIQVLALLLLRHLDAQAGGNVDELIDVISLSLGYYHEDPDDAAEDAPLRRVLALLAGAGVAVVASAGNQATTDKLFPAAFAEQVSGLDPGRVPLVSVGALNPDGTVAYFSNAGQWVTCHRPGAALVSTVPDDLDGDLQPRARLAAVGEKRATIDPENFTGGFASWSGTSFAAPVLAGQLAARIAQHRLAPLPEAKACLARGWDAVTDELGWVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEI5</accession>
    <name>A0A1Q2CEI5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CBS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_06575</name>
        <name evidence="4" type="ORF">SAMN05428934_103260</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06575"/>
    <dbReference type="EnsemblBacteria" id="AQP44516">
        <property type="protein sequence ID" value="AQP44516"/>
        <property type="gene ID" value="RPIT_06575"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71878">
        <property type="protein sequence ID" value="SDY71878"/>
        <property type="gene ID" value="SAMN05428934_103260"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06575"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="8"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="73"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY71878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="136" mass="13806" checksum="6D652D5A0063A14E" modified="2017-04-12" version="1">MKTARDLMTSPAHTLSPSDTLVEAARQLSAHGVGSMPVVDGGALVGVLTDRDIVVGGIAEGHDPASTPVSVIATTDVVSVSPDDDAQAVATAMSEHQIRRVPVVEDGKVVGVVSQADVALELDNSTAGEVVEGISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEM5</accession>
    <name>A0A1Q2CEM5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamyl-tRNA(Gln) amidotransferase subunit A</fullName>
            <shortName evidence="7">Glu-ADT subunit A</shortName>
            <ecNumber evidence="7">6.3.5.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gatA</name>
        <name evidence="9" type="ORF">RPIT_06510</name>
        <name evidence="10" type="ORF">SAMN05428934_103247</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the amidase family. GatA subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.7" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06510"/>
    <dbReference type="EnsemblBacteria" id="AQP44505">
        <property type="protein sequence ID" value="AQP44505"/>
        <property type="gene ID" value="RPIT_06510"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71532">
        <property type="protein sequence ID" value="SDY71532"/>
        <property type="gene ID" value="SAMN05428934_103247"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06510"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030956">
        <property type="term" value="C:glutamyl-tRNA(Gln) amidotransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00120">
        <property type="entry name" value="GatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004412">
        <property type="entry name" value="GatA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="PTHR11895"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="SSF75304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00132">
        <property type="entry name" value="gatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Amidase" evidence="8">
        <location>
            <begin position="25"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="7">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY71532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="497" mass="52496" checksum="EC0A09DD8A594093" modified="2017-04-12" version="1">MNPLLRLSAADLADMMSRGELTSEDLTRACLERIDAQNPTLNVFLSVDPEGALEAARAVDARRAAAEHLGPLAGIPIAVKDNFCTTDFATTCGSRMLEGWVPPYDATVVTRLRQAGLIIVGKTNMDEFAMGSSTETSAFGPTRNPWDTDRIPGGSGGGSAAAVASFMTPLAVGSDTGGSIRQPGSVTGTVGVKPTYGGVSRYGLVAMASSLDQPGPVARTAYDAALLHQIIGGYDPMDSASIDAPVGELATAARARSLDGVRVGVVKEFAGEGYEPGVLRRFEEAVDVLRAAGAEVVEVSCPHFTYALPTYYLIQPAELSSNLARFDGMRYGLRVGDDGTRSAEEVMNLTREAGFGREAKRRIIIGTYALSAGYYDAYYGSAQRVRTLIQRDFAAAFETVDVLVSPTTPTVAFKIGERVADPLSMYLADLCTIPSNMAGNASASFPAGLSDDGLPVGFQVMAPPLADERLYIIGGVLERALEARWGGPLLRELEAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEN2</accession>
    <name>A0A1Q2CEN2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RecBCD enzyme subunit RecD</fullName>
            <ecNumber evidence="10">3.1.11.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Exonuclease V subunit RecD</fullName>
            <shortName evidence="10">ExoV subunit RecD</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Helicase/nuclease RecBCD subunit RecD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">recD</name>
        <name evidence="13" type="ORF">RPIT_06930</name>
        <name evidence="14" type="ORF">SAMN05428934_11059</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Exonucleolytic cleavage (in the presence of ATP) in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides.</text>
            <dbReference type="EC" id="3.1.11.5"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the RecD family.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.5" evidence="10"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06930"/>
    <dbReference type="EnsemblBacteria" id="AQP44579">
        <property type="protein sequence ID" value="AQP44579"/>
        <property type="gene ID" value="RPIT_06930"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09288">
        <property type="protein sequence ID" value="SDZ09288"/>
        <property type="gene ID" value="SAMN05428934_11059"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06930"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009338">
        <property type="term" value="C:exodeoxyribonuclease V complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008854">
        <property type="term" value="F:exodeoxyribonuclease V activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01487">
        <property type="entry name" value="RecD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006344">
        <property type="entry name" value="RecD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041851">
        <property type="entry name" value="RecD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027785">
        <property type="entry name" value="UvrD-like_helicase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13538">
        <property type="entry name" value="UvrD_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01447">
        <property type="entry name" value="recD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5 10 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="12">
        <location>
            <begin position="175"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="183"/>
            <end position="190"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP44579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDZ09288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="567" mass="60161" checksum="88B8C79C11D29E99" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CES2</accession>
    <name>A0A1Q2CES2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Diaminopimelate epimerase</fullName>
            <shortName evidence="8">DAP epimerase</shortName>
            <ecNumber evidence="4 8">5.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">PLP-independent amino acid racemase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dapF</name>
        <name evidence="10" type="ORF">RPIT_07050</name>
        <name evidence="11" type="ORF">SAMN05428934_11034</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(2S,6S)-2,6-diaminoheptanedioate = meso-2,6-diaminoheptanedioate</text>
            <dbReference type="Rhea" id="RHEA:15393"/>
            <dbReference type="ChEBI" id="CHEBI:57609"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="5.1.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the diaminopimelate epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.7" evidence="4 8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07050"/>
    <dbReference type="EnsemblBacteria" id="AQP44601">
        <property type="protein sequence ID" value="AQP44601"/>
        <property type="gene ID" value="RPIT_07050"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08698">
        <property type="protein sequence ID" value="SDZ08698"/>
        <property type="gene ID" value="SAMN05428934_11034"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07050"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008837">
        <property type="term" value="F:diaminopimelate epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00197">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018510">
        <property type="entry name" value="DAP_epimerase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001653">
        <property type="entry name" value="DAP_epimerase_DapF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31689">
        <property type="entry name" value="PTHR31689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01678">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00652">
        <property type="entry name" value="DapF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01326">
        <property type="entry name" value="DAP_EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="83"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="207"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="217"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Could be important to modulate the pK values of the two catalytic cysteine residues" evidence="8">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <feature type="site" description="Could be important to modulate the pK values of the two catalytic cysteine residues" evidence="8">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDZ08698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="271" mass="29317" checksum="CB23E0BD5E5A09EF" modified="2017-04-12" version="1">MRRFSFHKGHGTQNDFIILDDSYGMHDMHPEFIKTMCDRRSGIGADGVIRVVRASSVREWTGEPSVWFMDYYNADGTTAEMCGNGLRVFARHLINEQLVDTGSFDVATRAGLKHVDVARHGLIRTDVGAATLVDEAVTVGLGEREWPAVKVDVGNPHAVVFVDDGELADLDLTRQPGWAPQDAYPNGVNVEFVHVDGPGKLSMRVHERGVGETKSCGTGVVAAAAAYRARTGFDSTIEVTVPGGELAVDFDGDDACLTGPAVIIGRGEFWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CES8</accession>
    <name>A0A1Q2CES8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_07200</name>
        <name evidence="4" type="ORF">SAMN05428934_1104</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44624">
        <property type="protein sequence ID" value="AQP44624"/>
        <property type="gene ID" value="RPIT_07200"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08051">
        <property type="protein sequence ID" value="SDZ08051"/>
        <property type="gene ID" value="SAMN05428934_1104"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07200"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ08051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="258" mass="27886" checksum="50290BF9B05EF4FE" modified="2017-04-12" version="1">MGTLRENRPVWYAVAWIAVYVIAVNIGDWLSEMVGEPNSATSALLVVLSLGLIVGLARDGWLRYFGVRAVRRRAFQSVLLYIPLALIASMQLTKGFRDDLTPTAVLLIVVLMICVGFLEELIFRGMLFRGIERSSNLTRAVVISGLTFGVGHVVNLARGMTLLEQSVQIGFGVVLGIVLALLFAVTGTIVPLIVFHALLNIIGNLTVADPGSELIMLAATTVVCVGYALYLVSVLRRRGPSPEMSQRPRRVTAPVAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEW9</accession>
    <name>A0A1Q2CEW9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07380</name>
        <name evidence="3" type="ORF">SAMN05428934_11433</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000014">
        <property type="protein sequence ID" value="SDZ18417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44653">
        <property type="protein sequence ID" value="AQP44653"/>
        <property type="gene ID" value="RPIT_07380"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ18417">
        <property type="protein sequence ID" value="SDZ18417"/>
        <property type="gene ID" value="SAMN05428934_11433"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07380"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ18417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="79" mass="8388" checksum="52E542FF1C8BD52E" modified="2017-04-12" version="1">MAGPFEDGLPLHPIADVVMGLSVLFGFSFPFIVLLVASGGWLYSNGDKTVRLVTVLGVRVLQANSSRSRALFNIPGQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEZ2</accession>
    <name>A0A1Q2CEZ2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07465</name>
        <name evidence="3" type="ORF">SAMN05428934_11912</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000019">
        <property type="protein sequence ID" value="SDZ21967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07465"/>
    <dbReference type="EnsemblBacteria" id="AQP44667">
        <property type="protein sequence ID" value="AQP44667"/>
        <property type="gene ID" value="RPIT_07465"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ21967">
        <property type="protein sequence ID" value="SDZ21967"/>
        <property type="gene ID" value="SAMN05428934_11912"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07465"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ21967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="159" mass="16863" checksum="B1EBA95985EFF53D" modified="2017-04-12" version="1">MAADTTTHSHPTTVSEPRDAAEDIRVALHRLSSSAPEEFFNIANDLRALGCDDAAVPFYEKAIEAGVPEATYNLALLHHERGRTEIARSGFVAASEAGDAKGAFMAAQIFEACGDDEAVVRMASTDHAQRVLRPMRSVMSPVSTCASLGETDAAAWSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFB2</accession>
    <name>A0A1Q2CFB2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Undecaprenyl-diphosphatase</fullName>
            <ecNumber evidence="4 14">3.6.1.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Bacitracin resistance protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 14">Undecaprenyl pyrophosphate phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">uppP</name>
        <name evidence="15" type="ORF">RPIT_08330</name>
        <name evidence="16" type="ORF">SAMN05428934_1159</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1T</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1</strain>
        </source>
    </reference>
    <reference evidence="15" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:28094"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="EC" id="3.6.1.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="14">Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the UppP family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.27" evidence="4 14"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08330"/>
    <dbReference type="EnsemblBacteria" id="AQP44804">
        <property type="protein sequence ID" value="AQP44804"/>
        <property type="gene ID" value="RPIT_08330"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19192">
        <property type="protein sequence ID" value="SDZ19192"/>
        <property type="gene ID" value="SAMN05428934_1159"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08330"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050380">
        <property type="term" value="F:undecaprenyl-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01006">
        <property type="entry name" value="Undec_diphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003824">
        <property type="entry name" value="UppP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30622">
        <property type="entry name" value="PTHR30622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02673">
        <property type="entry name" value="BacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00753">
        <property type="entry name" value="undec_PP_bacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="6 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="AQP44804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="SDZ19192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="274" mass="29470" checksum="7AA7BBBBAAFA1E66" modified="2017-04-12" version="1">MDWLQAIVLGIVQGLTEFLPISSSAHVSIVGQLLFDGRDPGAAFTAVTQLGTETAVLVYFRKDIWRIITHWIGSLRGTVEKGDPDARMGWLVIIGSVPIVVLGLLFQDAIDTTLRNLWITVAMLAGVALVLAAADRFGERNTKDLRQLSWRDGILLGLFQAAALIPGVSRSGATISGGLFLGFNREAAARYAFLLAVPAVFGSGLYKLKDIGDDTAATWGPTIVATILAFVIGYAVIAWLLRYISTHSFRIFVVYRLVIAAIVAVLILTGVLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFB7</accession>
    <name>A0A1Q2CFB7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08295</name>
        <name evidence="3" type="ORF">SAMN05428934_11516</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44798">
        <property type="protein sequence ID" value="AQP44798"/>
        <property type="gene ID" value="RPIT_08295"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19328">
        <property type="protein sequence ID" value="SDZ19328"/>
        <property type="gene ID" value="SAMN05428934_11516"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08295"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ19328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="167" mass="18434" checksum="8DF2C5BE20AF1B4C" modified="2017-04-12" version="1">MPAVTEQKVPDRLSYTSAPALMTSVVASAVLLSLALYGWWALGPGIRAQVTIAQAGTLLFFVLVMIGVMLSVGYSRLWAQDGVVTVRNGPFVRRYPVSEIAGFRLRPGDAWSSLLIKDDGDLKRKPVLAVQFLEGERGQRKVRELRRWLVEQGATSQGYDANRVDDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFD4</accession>
    <name>A0A1Q2CFD4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08430</name>
        <name evidence="3" type="ORF">SAMN05428934_12010</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000020">
        <property type="protein sequence ID" value="SDZ22295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44818">
        <property type="protein sequence ID" value="AQP44818"/>
        <property type="gene ID" value="RPIT_08430"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ22295">
        <property type="protein sequence ID" value="SDZ22295"/>
        <property type="gene ID" value="SAMN05428934_12010"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08430"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544465" evidence="1">
        <location>
            <begin position="25"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ22295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="201" mass="20962" checksum="D7A06BFB74E3002F" modified="2017-04-12" version="1">MLRIRLAALATASVLILGPLTACSSGPSPEAGTAVTSGALDAASEGAGLLEAQGLAGKTGREIVEALDQLDAPRPLPVAASVRYDEVVVTDGVTEEVLPIEDQFYLSLAPYETSTHECYFHNLGTCRGELADTDVHVTITTDDGEVLVDEDATTYANGFVGFWVPRDVTGTIQVTKDGKTAESAFSSDPEGATCVTTLQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFE3</accession>
    <name>A0A1Q2CFE3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6 7">50S ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplS</name>
        <name evidence="8" type="ORF">RPIT_08565</name>
        <name evidence="9" type="ORF">SAMN05428934_10724</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6 7">This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 7">Belongs to the bacterial ribosomal protein bL19 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY96677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08565"/>
    <dbReference type="EnsemblBacteria" id="AQP44836">
        <property type="protein sequence ID" value="AQP44836"/>
        <property type="gene ID" value="RPIT_08565"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY96677">
        <property type="protein sequence ID" value="SDY96677"/>
        <property type="gene ID" value="SAMN05428934_10724"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08565"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00402">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038657">
        <property type="entry name" value="L19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001857">
        <property type="entry name" value="Ribosomal_L19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018257">
        <property type="entry name" value="Ribosomal_L19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680">
        <property type="entry name" value="PTHR15680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01245">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002191">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00061">
        <property type="entry name" value="RIBOSOMALL19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01024">
        <property type="entry name" value="rplS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01015">
        <property type="entry name" value="RIBOSOMAL_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 8" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY96677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="116" mass="13103" checksum="536794035B031002" modified="2017-04-12" version="1">MTNPLIQEINKASLRDDIPDFRAGDSVKVHVKVVEGTRSRVQVFAGVVIARNAGDVQEAFTVRKVSFGVGVERTFPLHSPIIEKIEVERRGDVRRAKLYYLRGLRGKAAKIKEKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFG9</accession>
    <name>A0A1Q2CFG9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chromosome partition protein Smc</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">smc</name>
        <name evidence="8" type="ORF">RPIT_08670</name>
        <name evidence="9" type="ORF">SAMN05428934_10744</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for chromosome condensation and partitioning.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SMC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08670"/>
    <dbReference type="EnsemblBacteria" id="AQP44853">
        <property type="protein sequence ID" value="AQP44853"/>
        <property type="gene ID" value="RPIT_08670"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97142">
        <property type="protein sequence ID" value="SDY97142"/>
        <property type="gene ID" value="SAMN05428934_10744"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08670"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01894">
        <property type="entry name" value="Smc_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011890">
        <property type="entry name" value="SMC_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="SSF75553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02168">
        <property type="entry name" value="SMC_prok_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="7">
        <location>
            <begin position="508"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="755"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="860"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="930"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="167"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="255"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="334"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="390"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="647"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="989"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="32"/>
            <end position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY97142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="1176" mass="126916" checksum="205725168DC16DFE" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFM2</accession>
    <name>A0A1Q2CFM2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">6-phosphogluconate dehydrogenase, decarboxylating</fullName>
            <ecNumber evidence="3 7">1.1.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_08955</name>
        <name evidence="10" type="ORF">SAMN05428934_107104</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 7">
            <text>6-phospho-D-gluconate + NADP(+) = CO2 + D-ribulose 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:10116"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="1.1.1.44"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 7">Belongs to the 6-phosphogluconate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.44" evidence="3 7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08955"/>
    <dbReference type="EnsemblBacteria" id="AQP44903">
        <property type="protein sequence ID" value="AQP44903"/>
        <property type="gene ID" value="RPIT_08955"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98332">
        <property type="protein sequence ID" value="SDY98332"/>
        <property type="gene ID" value="SAMN05428934_107104"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08955"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004616">
        <property type="term" value="F:phosphogluconate dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019521">
        <property type="term" value="P:D-gluconate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016054">
        <property type="term" value="P:organic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006114">
        <property type="entry name" value="6PGDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006113">
        <property type="entry name" value="6PGDH_Gnd/GntZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006183">
        <property type="entry name" value="Pgluconate_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11811">
        <property type="entry name" value="PTHR11811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00393">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000109">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00076">
        <property type="entry name" value="6PGDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01350">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00873">
        <property type="entry name" value="gnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="3 7" id="KW-0521">NADP</keyword>
    <keyword evidence="3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 7" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6PGD" evidence="8">
        <location>
            <begin position="182"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="132"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="189"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="13"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="36"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="78"/>
            <end position="80"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="454"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY98332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="482" mass="51438" checksum="4917C7963CF689D0" modified="2017-04-12" version="1">MPAEQLANVGVIGMAVMGSNLARNLARNGHRVALYNRTTAKTDGVMADHGHEGDFVPSIDLPEFVASLERPRRIILMVKAGPATDATIEAMLPLLDEGDIVVDGGNSLFTDTRRREARLRELGLHFVGAGISGGEVGALEGPSIMPGGSKESYLALGPILESISAKVDGEPCCAYIGTDGAGHFVKMVHNGIEYADMQFIGEAYELLKGLGLSHDEMADVFATWNTGDLDSYLIEITSDVLRKTDPSTGVPLLEVIVDAAGMKGTGTWTVQSALDLGTPVNTIAESVFARAISSSPALRSAAQAALSGPDASITVDDRVAFVDEIRQALWASKVIAYAQGLDEIRMAGEEYGWQIDVGEVAKIWRGGCIIRAKLLERIRSEYAAQNLTTLLEAPSVAEGLADAQEAWRNVIAVAVKAGVPVPGFSAALAHYDQARAPRLNAALTQGLRDYFGAHTYRRVDREGSFHINWSTDGAEIEAVDLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFS5</accession>
    <name>A0A1Q2CFS5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44947">
        <property type="protein sequence ID" value="AQP44947"/>
        <property type="gene ID" value="RPIT_09240"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09240"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="222" mass="24272" checksum="4443AA28C2056CF7" modified="2017-04-12" version="1">MNGRDEDVFKQPDGHAARRAARDSDGPVYDELDGPVLRPEPVGLSGLWRRRIAQGLVWVGRAVMVAWPLGFVVTRLTSGIWMSASSEDGLPVHPITDVMMGLSFIFAMGVPVFLLPVASGVWLYPRGDGTVRVPTVLGTRVLEADSVSTRPLFELPGRGWGITVTLVRDRTSRWFLMADSGLWHDEEGSIVLGMLAILAWSAVTVLVWAVLIELTFLGTPSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFT3</accession>
    <name>A0A1Q2CFT3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyltransferase, GT2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09295</name>
        <name evidence="4" type="ORF">SAMN05428934_102450</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY61096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09295"/>
    <dbReference type="EnsemblBacteria" id="AQP44957">
        <property type="protein sequence ID" value="AQP44957"/>
        <property type="gene ID" value="RPIT_09295"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY61096">
        <property type="protein sequence ID" value="SDY61096"/>
        <property type="gene ID" value="SAMN05428934_102450"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09295"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027791">
        <property type="entry name" value="Galactosyl_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02709">
        <property type="entry name" value="Glyco_transf_7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_7C" evidence="2">
        <location>
            <begin position="174"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY61096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="280" mass="30358" checksum="2A774343D7EB9008" modified="2017-04-12" version="1">MSRVAVVTAVAGRHEHLRAQRRGLARSTEPVTHVVVAMGDPSIWEVCLEPPCVPTEYLRVPAAQELPLAAARNAGVACARRMGADVVVFLDVDCIPSETLATDYLEVLGALGRLDGDCGGPAVVTGRTQYLPPAPEGGYDLDALTKVGRDHPARPVPEDGAVVEGDVRLLWTLNCALTVDDFDAVGGFDEGYHGYGGEDTDFGQRLGHAQGKLWFTASARAWHQHHAVSDPPVEHLDAILRNANRFQSLWGWFPMEGWLAGFQNAGLAHQRDGKWQKVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFW7</accession>
    <name>A0A1Q2CFW7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09590</name>
        <name evidence="3" type="ORF">SAMN05428934_102388</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY59457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09590"/>
    <dbReference type="EnsemblBacteria" id="AQP45008">
        <property type="protein sequence ID" value="AQP45008"/>
        <property type="gene ID" value="RPIT_09590"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59457">
        <property type="protein sequence ID" value="SDY59457"/>
        <property type="gene ID" value="SAMN05428934_102388"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09590"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043777">
        <property type="entry name" value="DUF5719"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18986">
        <property type="entry name" value="DUF5719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544473" evidence="1">
        <location>
            <begin position="36"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY59457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="412" mass="40501" checksum="48FCD4892F2B32FB" modified="2017-04-12" version="1">MIRRTALSLAALLAVVAVAALLALLSPARQTPPVAVDLPQTSRVVCLVAGRVLVRDVANVEVRGLSGNAESAEGGELTIDEPVVLRAERRLAAGVLVEQEQRSYAPCQPAVTSGMVVVADPASTELILANADGNEATVDLTLLGADGEVVAVGARGIALAPGSTRRVALSVLAPDGPVGVAFRASQGRVALIGAAVEGRPTRFTPPSDPSTEHVVGGIPAGATAVQLLVSNPHENRVEVSVEALGASASFEPASATGISVAPRSTMAIDLGDALAGEAAALQIAADQAVGVSVVAGVGAGSPATLTGGVASSELSLNAPGGSALVVSNPGDGEATVDVSVGGADQQLTVDAGLTVAVPLPEGGQLEVDLSADSPVVAAAVSATEAGTVVVPAADSVDAAVRGVPARLDPTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFW8</accession>
    <name>A0A1Q2CFW8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyltransferase, GT2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_09595</name>
        <name evidence="5" type="ORF">SAMN05428934_102387</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY59433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09595"/>
    <dbReference type="EnsemblBacteria" id="AQP45009">
        <property type="protein sequence ID" value="AQP45009"/>
        <property type="gene ID" value="RPIT_09595"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59433">
        <property type="protein sequence ID" value="SDY59433"/>
        <property type="gene ID" value="SAMN05428934_102387"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09595"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="487"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="548"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="582"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="641"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="667"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="700"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="727"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="3">
        <location>
            <begin position="37"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY59433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="983" mass="104200" checksum="D138607BAB34C5A7" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFX5</accession>
    <name>A0A1Q2CFX5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">N5-carboxyaminoimidazole ribonucleotide mutase</fullName>
            <shortName evidence="3 4">N5-CAIR mutase</shortName>
            <ecNumber evidence="3 4">5.4.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">5-(carboxyamino)imidazole ribonucleotide mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">purE</name>
        <name evidence="7" type="ORF">RPIT_09635</name>
        <name evidence="8" type="ORF">SAMN05428934_102378</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate</text>
            <dbReference type="Rhea" id="RHEA:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="EC" id="5.4.99.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AIR carboxylase family. Class I subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.18" evidence="3 4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY59168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09635"/>
    <dbReference type="EnsemblBacteria" id="AQP45016">
        <property type="protein sequence ID" value="AQP45016"/>
        <property type="gene ID" value="RPIT_09635"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59168">
        <property type="protein sequence ID" value="SDY59168"/>
        <property type="gene ID" value="SAMN05428934_102378"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09635"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00943"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034023">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01929">
        <property type="entry name" value="PurE_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033747">
        <property type="entry name" value="PurE_ClassI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024694">
        <property type="entry name" value="PurE_prokaryotes"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001338">
        <property type="entry name" value="AIR_carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01162">
        <property type="entry name" value="purE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1 3 4" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRC" evidence="6">
        <location>
            <begin position="4"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001338-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY59168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="166" mass="17229" checksum="40E8C5DE488E8626" modified="2017-04-12" version="1">MPEPLVSIVMGSDSDWPTMSAAGDALAEFGVPFEADVVSAHRMPEDMVTFGRQAHTRGIRVIIAGAGGAAHLPGMLAALTPLPVIGVPVPLKYLDGMDSLLSIVQMPAGVPVATVAIGNARNAGLLAVRMLAAGDERLTQRMLEFQESLRDAAHAKGAVVRDALAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG15</accession>
    <name>A0A1Q2CG15_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_09900</name>
        <name evidence="6" type="ORF">SAMN05428934_102326</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY57628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09900"/>
    <dbReference type="EnsemblBacteria" id="AQP45062">
        <property type="protein sequence ID" value="AQP45062"/>
        <property type="gene ID" value="RPIT_09900"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57628">
        <property type="protein sequence ID" value="SDY57628"/>
        <property type="gene ID" value="SAMN05428934_102326"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09900"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="13"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="154"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY57628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="221" mass="23910" checksum="4C643650B8632C89" modified="2017-04-12" version="1">MNDEAPKRLSDLKVVIVDDHAMFRAGVRHEIGQHVHVTAEADDVASAVDAITRTDPDVVLLDVHLPGGGGAEVIKQTLAIKPNVKFLALSVSDAAQDVIGVIRAGARGYVTKSISSDELLEGMARVAGGDAVFSPRLAGFVLDAFSGAIDVSGIDEELDKLSAREREVLKLIARGYAYKEVARELFISIKTVETHVSSVLRKLQLSNRHQLTKWATDRHLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG30</accession>
    <name>A0A1Q2CG30_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chorismate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09945</name>
        <name evidence="3" type="ORF">SAMN05428934_102317</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY57357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09945"/>
    <dbReference type="EnsemblBacteria" id="AQP45071">
        <property type="protein sequence ID" value="AQP45071"/>
        <property type="gene ID" value="RPIT_09945"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57357">
        <property type="protein sequence ID" value="SDY57357"/>
        <property type="gene ID" value="SAMN05428934_102317"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09945"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046417">
        <property type="term" value="P:chorismate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.59.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036263">
        <property type="entry name" value="Chorismate_II_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010951">
        <property type="entry name" value="CM_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036979">
        <property type="entry name" value="CM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002701">
        <property type="entry name" value="CM_II_prokaryot"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01817">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00830">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48600">
        <property type="entry name" value="SSF48600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01795">
        <property type="entry name" value="CM_mono_cladeE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51168">
        <property type="entry name" value="CHORISMATE_MUT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate mutase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY57357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="97" mass="10918" checksum="21625838DA47CF86" modified="2017-04-12" version="1">MDEAEAELKRLRGSIDNMDSALIHLLAERFKVTQRVGQLKATAGLPPADPQREAHQIARLRALAVEADLDPELAEKFLTFIVREVVRHHEQIAAEQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG43</accession>
    <name>A0A1Q2CG43_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional attenuator, LytR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_09630</name>
        <name evidence="6" type="ORF">SAMN05428934_102379</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LytR/CpsA/Psr (LCP) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY59202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09630"/>
    <dbReference type="EnsemblBacteria" id="AQP45015">
        <property type="protein sequence ID" value="AQP45015"/>
        <property type="gene ID" value="RPIT_09630"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59202">
        <property type="protein sequence ID" value="SDY59202"/>
        <property type="gene ID" value="SAMN05428934_102379"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09630"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004474">
        <property type="entry name" value="LytR_CpsA_psr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03816">
        <property type="entry name" value="LytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00350">
        <property type="entry name" value="lytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="LytR_cpsA_psr" evidence="4">
        <location>
            <begin position="154"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY59202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="391" mass="41792" checksum="2A7AF2E676D8BBB6" modified="2017-04-12" version="1">MPKRDDDLEWLYRQDQPDETAVLRPDEAERLRSQGEYPAHDTRPGSPPPQGRRRGSAAPTPPTPPPAPPARGRRRRRHPMRRFVLTLLALWLVFLIGTPLYAWIAATRVEAAPTGDRPGDQPGSTVLLVGSDGRDDLTAEERNRLGTGSAEGRRTDTMMLVHTPSEGPAVLLSLPRDSYVSIPGYGSNKLNAAYAFGGAPLLVETIESNTGVRIDGYLEIGMLGLVNVVDAVGGIEVCPTFDIDDRDSHLTLAEGCQTVDGVTALGYARMRKSDPDGDLGRVARQREVIASVVRKTATPLSILNPVTYWRLNMAASDSLARGEDTGLVEMAQVGRAFVGVMTGSGLSLTVPVANADASTDAGSAVLWAEDASADLFGAIASGDTTTLESLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG84</accession>
    <name>A0A1Q2CG84_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Globin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09940"/>
    <dbReference type="EnsemblBacteria" id="AQP45070">
        <property type="protein sequence ID" value="AQP45070"/>
        <property type="gene ID" value="RPIT_09940"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09940"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005344">
        <property type="term" value="F:oxygen carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019795">
        <property type="entry name" value="Globin_bac-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001486">
        <property type="entry name" value="Hemoglobin_trunc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01152">
        <property type="entry name" value="Bac_globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01213">
        <property type="entry name" value="GLOBIN_FAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0561">Oxygen transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="133" mass="15266" checksum="129C254E8FCC2259" modified="2017-04-12" version="1">MAPRGARVTQQPFYDRVGGAATFERLVARFYEGVASDPPLRALYPEDDLGPAADRLRMFLEQYWGGPKTYQEQRGHPRLRMRHFDYAVTPAQRDRWVHHMLVAVESLGLDPADAETMREYLVRAADFLVNADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGC3</accession>
    <name>A0A1Q2CGC3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Glutamine--fructose-6-phosphate aminotransferase [isomerizing]</fullName>
            <ecNumber evidence="2 8">2.6.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">GFAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Glucosamine-6-phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Hexosephosphate aminotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">L-glutamine--D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">glmS</name>
        <name evidence="11" type="ORF">RPIT_10085</name>
        <name evidence="12" type="ORF">SAMN05428934_102288</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="2 8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10085"/>
    <dbReference type="EnsemblBacteria" id="AQP45095">
        <property type="protein sequence ID" value="AQP45095"/>
        <property type="gene ID" value="RPIT_10085"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56632">
        <property type="protein sequence ID" value="SDY56632"/>
        <property type="gene ID" value="SAMN05428934_102288"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10085"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
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    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="initiator methionine" description="Removed" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="9">
        <location>
            <begin position="2"/>
            <end position="216"/>
        </location>
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        <location>
            <begin position="284"/>
            <end position="423"/>
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            <position position="2"/>
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            <dbReference type="PROSITE" id="PS51464"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="610" mass="66592" checksum="FE4BA2601C319DB8" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
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        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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            <begin position="24"/>
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    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY52998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="210" mass="23274" checksum="1D3E6B085692E89D" modified="2017-04-12" version="1">MTELERLRGVMAELRVKCPWDAKQTHRSLLNHLIEEACEVVDAVEAGDDTELIEELGDLLLQVYFHARIAEDEGRFTLDDVARGISDKLVRRHPHVFADEDVPHDMWQSWEERKREEKGRTSALEGIAQSLSVIGRAHKVVSRSRTHGVDVGLPGDAITEAEVGQQIIALVARAQAHGIDADAAARHALRDLEGRIAAAEGHPDVARQVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGJ2</accession>
    <name>A0A1Q2CGJ2_9ACTN</name>
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        <submittedName>
            <fullName evidence="4">Assimilatory nitrate reductase (NADH) beta subunit</fullName>
        </submittedName>
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        <name evidence="3" type="ORF">RPIT_10895</name>
        <name evidence="4" type="ORF">SAMN05428934_102125</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10895"/>
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        <property type="protein sequence ID" value="AQP45238"/>
        <property type="gene ID" value="RPIT_10895"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY51798"/>
        <property type="gene ID" value="SAMN05428934_102125"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007419">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041854">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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            <begin position="4"/>
            <end position="284"/>
        </location>
    </feature>
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        <location>
            <begin position="428"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY51798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="493" mass="50826" checksum="A1CC304AD18430FB" modified="2017-04-12" version="1">MSHRIVVVGHGMVGHRFLADLAAHRLEGTRTTVLGDEPHPAYNRILLPDVLLGRSDLAGLTLPETPGVRLLRGRRAATIDRLRGVVVDSTGEEHPFDTLVLALGADPVFPTVDGVVGADGNPLPGVAALRTWDDAHRVRSAAEEGARVVVMGGGVLGVEAAVALAAAGSEVTVVHRGSTPLDRQFDADSGAVVRAGLADLGITTLVDVRVSGVERRRDGTLASVRLTDERHIPADLLLVAIGVRPRTRLAEEADLGVRNGILVNDSCRTDDPAIYAIGDCARTPRGCSGLVGPGWEQARVLAHHLAERISGRSRPRPVLGADGGVFRVKAEGLEAVTMGEFPDDEFTPGAARVLSLTDPAGRRRVRLAVADGLLVGATCVGDPQVAADLTVAFDSRTPVPDDPAALLARPLAGASAPASVVDLPETAVVCRCNAVTKSAITAAVAAGADTAEAVANATRASTGCGSCTSDVCRLVSALGEAGGSRSLDRVTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGL6</accession>
    <name>A0A1Q2CGL6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">Transcription elongation factor GreA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Transcript cleavage factor GreA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">greA</name>
        <name evidence="11" type="ORF">RPIT_10570</name>
        <name evidence="12" type="ORF">SAMN05428934_102191</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7 8">Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the GreA/GreB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY53823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10570"/>
    <dbReference type="EnsemblBacteria" id="AQP45185">
        <property type="protein sequence ID" value="AQP45185"/>
        <property type="gene ID" value="RPIT_10570"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY53823">
        <property type="protein sequence ID" value="SDY53823"/>
        <property type="gene ID" value="SAMN05428934_102191"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10570"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00105">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018151">
        <property type="entry name" value="TF_GreA/GreB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006359">
        <property type="entry name" value="Tscrpt_elong_fac_GreA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028624">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022691">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036805">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03449">
        <property type="entry name" value="GreA_GreB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006092">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46557">
        <property type="entry name" value="SSF46557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01462">
        <property type="entry name" value="greA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00829">
        <property type="entry name" value="GREAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00830">
        <property type="entry name" value="GREAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="GreA_GreB_N" evidence="10">
        <location>
            <begin position="9"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="GreA_GreB" evidence="9">
        <location>
            <begin position="86"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP45185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY53823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="167" mass="18061" checksum="F721147514639217" modified="2017-04-12" version="1">MSETAADVVWLTQEAFEKLEAELNELKTVGREEVSARIASAREEGDLSENGGYHAAREEQGLMEGRIRQLEDLLRRAKVGQSQGAADEVAPGKLITVAYDGDDSDTDTFLLGSREVLGVDDSVDHQVYSPQSPLGSAIVGAKVGDEVRYEAPNGKELMVVVLKVETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGM3</accession>
    <name>A0A1Q2CGM3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L25</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">General stress protein CTC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplY</name>
        <name evidence="6" type="synonym">ctc</name>
        <name evidence="9" type="ORF">RPIT_10730</name>
        <name evidence="10" type="ORF">SAMN05428934_102159</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY52867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10730"/>
    <dbReference type="EnsemblBacteria" id="AQP45210">
        <property type="protein sequence ID" value="AQP45210"/>
        <property type="gene ID" value="RPIT_10730"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY52867">
        <property type="protein sequence ID" value="SDY52867"/>
        <property type="gene ID" value="SAMN05428934_102159"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10730"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00495">
        <property type="entry name" value="Ribosomal_L25_TL5_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01334">
        <property type="entry name" value="Ribosomal_L25_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_L25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029751">
        <property type="entry name" value="Ribosomal_L25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_L25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020057">
        <property type="entry name" value="Ribosomal_L25_b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037121">
        <property type="entry name" value="Ribosomal_L25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001021">
        <property type="entry name" value="Ribosomal_L25_long"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01386">
        <property type="entry name" value="Ribosomal_L25p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14693">
        <property type="entry name" value="Ribosomal_TL5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="SSF50715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00731">
        <property type="entry name" value="bL25_bact_ctc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_TL5_C" evidence="8">
        <location>
            <begin position="100"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="183"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY52867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="210" mass="22494" checksum="F2E9CC4795DDF089" modified="2017-04-12" version="1">MADINITATTRTEFGKGAARRLRRAGQTPAVLYGHGTEPMHLALPAQEAFLALRQPNVLLHLKVEGESKPILALPKQVQRDPILPAIDHIDLLIVRAGEKVTVDVPLHITGEVERGNLVNIDLNNLTVLAPATNIPTEFEVSIEGLTAGDHITVADIKLLEGVEAAVDGEHLVLNVVVAPTQDLESSDEESAEDVEAIHGDEAEGDDADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGM4</accession>
    <name>A0A1Q2CGM4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Pyruvate-ferredoxin/flavodoxin oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="14">Pyruvate:ferredoxin (Flavodoxin) oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">RPIT_11095</name>
        <name evidence="15" type="ORF">SAMN05428934_10285</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1T</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1</strain>
        </source>
    </reference>
    <reference evidence="14" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 3 [4Fe-4S] clusters per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY50570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11095"/>
    <dbReference type="EnsemblBacteria" id="AQP45272">
        <property type="protein sequence ID" value="AQP45272"/>
        <property type="gene ID" value="RPIT_11095"/>
    </dbReference>
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</entry>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">RP1T</strain>
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                <person name="de Groot N.N."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
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    </reference>
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        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <sequence length="223" mass="24514" checksum="C76DDD5252D8DFA1" modified="2017-04-12" version="1">MDILFDTANLDDIERLTPIYPVTGVTTNPSILKAEGKIDFYPHMRRIREIIGPNRTLHVQVLAKTAQGMIDDAHRLLDKIDADVYPKIPTTEAGIAAMRHLKEEGVKVTATAIYSKTQGFLAIATGVDYLAPYYNRMQSLDIDTRGTIEVLAGFIKRFDAPGKIMAASFKNVAQVSHALESGADAVTLSPKLLRAALSAPDIDRAVDDFIKDWKAIYGTTELP</sequence>
</entry>
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    <name>A0A1Q2CGX8_9ACTN</name>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name type="scientific">Tessaracoccus flavus</name>
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            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11655"/>
    <dbReference type="EnsemblBacteria" id="AQP45371">
        <property type="protein sequence ID" value="AQP45371"/>
        <property type="gene ID" value="RPIT_11655"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93820">
        <property type="protein sequence ID" value="SDY93820"/>
        <property type="gene ID" value="SAMN05428934_106144"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11655"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="4">
        <location>
            <begin position="407"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY93820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="495" mass="53159" checksum="9EA5B1252DABADF6" modified="2017-04-12" version="1">MRSIWFDLHSDSARPSGARLDGLKAQVVVAGAGLTGLATAVLLARSGQEVILLEDRRVGAVTTGHTTAKLSLLQGSVYSEILKRNSEEVLAAYLEGNREGQAWLTRYMDDRGIAYQRRDAWTFAMTQDGLKDLGAEFDACHAVGLDLQQPAETELPFPVEGALRLPDQVQIDPVAVLESLRTEFVEHGGRLFEGVRVTDATSSSPVEVTTTRGTVTAGRLVLATGSPILDRGGHFAKLVPQRSYVTTYRVPGAIPQGMYLSVDEPTRSLRTVPTPDGELLMVGGNGHITGRADYESLAVEDLVAWTTRYFPGAELTHSWSAQDYQPHDRLPFAGPLPRGGGAIYAATGFNKWGMANAIAAALNLSQQILGGSMEWADTLNNRPVQPRTMMTGIKETAGVAGELVKEWATAELKALPDEPPEEGDGVVGRDGVQPVGMSTVDGETCKVSGVCTHMGGVLRWNDAERSWDCPLHGSRFAADGTRLEGPAVEDLEKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH62</accession>
    <name>A0A1Q2CH62_9ACTN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12070"/>
    <dbReference type="EnsemblBacteria" id="AQP45447">
        <property type="protein sequence ID" value="AQP45447"/>
        <property type="gene ID" value="RPIT_12070"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12070"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="473"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="778" mass="84329" checksum="1EE176C57E92DDF3" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH71</accession>
    <name>A0A1Q2CH71_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_12145</name>
        <name evidence="10" type="ORF">SAMN05428934_10647</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY91694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12145"/>
    <dbReference type="EnsemblBacteria" id="AQP45462">
        <property type="protein sequence ID" value="AQP45462"/>
        <property type="gene ID" value="RPIT_12145"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY91694">
        <property type="protein sequence ID" value="SDY91694"/>
        <property type="gene ID" value="SAMN05428934_10647"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12145"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="182"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="258"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY91694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="473" mass="49580" checksum="EFBF902C84EEC629" modified="2017-04-12" version="1">MTRSKGTLASQLQPRVVITVAVMTLLVSLATVVAARSILYGQLDAELEATQVLQGLGGQAGGGGAVPGIETPGIQRGTIMALRLPNGTELGSLVGDGAFEPISSAAGQALLEVPADDQKHTVALPGYGGYRVEAHTTPAGQLVVGLPTSDINRSLLWLSLFAVGVSLVAVSATALVTRTVIDRATEPLVALTETADEVSRLELARGTVEVPRMQGPMLPENNEVTRLSEAFDQMLGRVEEALGAREASEAKLRRFVADASHELRNPLAAIRGYAELAGRAPTPQDAAFATRRIGAESERMTKLVQDLLLLARLDSEVTPEPRPVDVVEVVLNAVSDAQAAGRTHRWLLNLPDDAVEVLADADQLQQVMVNLLSNARTHTPAGTTVTTSVWVDGATATVEVADDGAGIPPEILPHVFERFARADDSRAHSAAHSTGLGLAIVKAVVEGFGGTASVHSAPGDTRFRITLPLAGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH76</accession>
    <name>A0A1Q2CH76_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cystathione beta-lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12190</name>
        <name evidence="3" type="ORF">SAMN05428934_10638</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">RP1T</strain>
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    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
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            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="RPIT_12190"/>
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        <location>
            <begin position="60"/>
            <end position="361"/>
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    <evidence type="ECO:0000259" key="1">
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    </evidence>
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            <dbReference type="EMBL" id="AQP45469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY91512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="377" mass="41012" checksum="56A754423AB4E7FF" modified="2017-04-12" version="1">MAIFNVPLTELQQRRTIKWRRFEPDVLPMFVAEMDAHLAAPVRERLERALAMGDTGYPQLPDYQEAFADFAQWMWGWSIEPKQFKLATDVVTGMREAVLGLTAPGDAVVINPPIYPPFRMVSPDRHLVEVPLGDDGRLDLDGLAEAFARPETTAYLLCSPHNPAGTIHTVDELTEVARLASEHGVAVISDEIHAPLAGSAHTPYLQVPGAANALVVTSASKSWNLAAVKAALVIGEHELLRKLAGTMQDGASYFGILAHSEALSEGRAWLAQAQLEIDANKRLFADLLAARLPQLSHEPSEGTYLAWLDCSALGLENPGAHFHEVGRVRFNLGSEFSPAHQQFVRVNLATSPAIIEEAVDRMARSLDGAPLGRSANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH82</accession>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Schumann P."/>
                <person name="Lal R."/>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
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    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    </dbReference>
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            <begin position="15"/>
            <end position="35"/>
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            <begin position="47"/>
            <end position="68"/>
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            <end position="96"/>
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            <end position="121"/>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="AQP45478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY91230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="134" mass="13884" checksum="09653E2B5859CBF8" modified="2017-04-12" version="1">MSTTPERPADRPARVRSTIIVLSVGMGLLLLFAYAAETLFDRAPGGAFFFVVPVIGFLIPMLLSALSVPRERRGLVVGLALASAAVAAATLVVSAIFEWTHWLPWIAGTVASVALGLGAALGAGDAVPRTEVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHE5</accession>
    <name>A0A1Q2CHE5_9ACTN</name>
    <protein>
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        <submittedName>
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    </protein>
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        <name evidence="6" type="ORF">RPIT_12555</name>
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
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    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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        <text evidence="1">Belongs to the type IB topoisomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="AQP45532"/>
        <property type="gene ID" value="RPIT_12555"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY79889"/>
        <property type="gene ID" value="SAMN05428934_104175"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="82"/>
            <end position="288"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00006645"/>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP45532.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY79889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="332" mass="36581" checksum="8E3B236E2A553105" modified="2017-04-12" version="1">MARLRRVSARMPGFTRRKRGKGFSYLDADGDALPTEEVERIRSLAIPPAWTDVWICPYPNGHLQAVGTDDAGRRQYLYHPDWRKRRDRSKFDRVAAAAEMLPTARRRITADLRQDGMPLERAAACAVRLLDVGYFRIGNDAYTDAHGSFGLTTLERSHVRRRGSDLIFSFVGKSGISHTIAVDDADAIAALETMRARRDDSPRLLAFKGADGWQVLSSADVNGYLAELFGGALTAKDFRTWHATVIAAEVLALAEEEGRSKASRNRAIKQAVHEVAGYLGNTPTVARNSYIDPRVIDAYESGSTIGDAATKRYSSAQARQTGLEKAVLDLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHI9</accession>
    <name>A0A1Q2CHI9_9ACTN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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        <name evidence="2" type="ORF">SAMN05428934_104177</name>
    </gene>
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    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY79945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45530">
        <property type="protein sequence ID" value="AQP45530"/>
        <property type="gene ID" value="RPIT_12545"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY79945">
        <property type="protein sequence ID" value="SDY79945"/>
        <property type="gene ID" value="SAMN05428934_104177"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12545"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY79945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="144" mass="15379" checksum="541A65889226265A" modified="2017-04-12" version="1">MSKLGILVKTAGGVIATTATLLTALRENPQIARSIDDAVGKLKASANSENPKLRFDAKLNAINVAADAVDETFPGSPEPEGWRRQAQALRVRGELAWSANTGKHRRTAMKALNAETAELLQQINERLASMQAPTEIPPASDASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHJ7</accession>
    <name>A0A1Q2CHJ7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LacI family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_12850</name>
        <name evidence="6" type="ORF">SAMN05428934_104117</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY78210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12850"/>
    <dbReference type="EnsemblBacteria" id="AQP45584">
        <property type="protein sequence ID" value="AQP45584"/>
        <property type="gene ID" value="RPIT_12850"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY78210">
        <property type="protein sequence ID" value="SDY78210"/>
        <property type="gene ID" value="SAMN05428934_104117"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12850"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="14"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY78210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="348" mass="36982" checksum="0B8DB3E5E1303DBF" modified="2017-04-12" version="1">MNAELARGAGDRPPTMRDVATAAGVGLKTVSRYVNGETNIADPLRVRIAEAIELLGYRRNLAAASIRPGWTSKVIGLITSDLANPYYSTLAHAAESVAWQAGYLLTTFSSEEDGERHDLAVDRLIDQRVDALLIVPPRNPGRAWSQLRPPLPPVVFLDRPAVLDGAPAVLADNAGGAREAAIELARNGARRIAFVGDSQQIYTMAERLRGYLDGLAQVGLTPGPISHAAHSQEEARGVVSGLLAEGAADAIFAANNRAAMGALHAFADSGGRLPMIAFDDFEAAEVVRPRISVVSQDVARMGALATEIAIRILQGTPPVSDRTVLGTRLILRGSEKPDSPTILDRLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHK1</accession>
    <name>A0A1Q2CHK1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase/protein kinase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">LAO/AO transport system kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12675</name>
        <name evidence="3" type="ORF">SAMN05428934_104152</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY79219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12675"/>
    <dbReference type="EnsemblBacteria" id="AQP45553">
        <property type="protein sequence ID" value="AQP45553"/>
        <property type="gene ID" value="RPIT_12675"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY79219">
        <property type="protein sequence ID" value="SDY79219"/>
        <property type="gene ID" value="SAMN05428934_104152"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12675"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005129">
        <property type="entry name" value="GTPase_ArgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23408">
        <property type="entry name" value="PTHR23408"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00750">
        <property type="entry name" value="lao"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY79219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="344" mass="36992" checksum="4D36BD7A93FD31F5" modified="2017-04-12" version="1">MRKVTIEELADKIAEGSRGHIARAITLVESTKPAHREQAHELLQRIAPRTGGAFRVGVSGVPGAGKSTFIDAMGVKLIDERGHKVAVLAVDPSSSRTGGSILGDRTRMSELAQRENAFIRPSPSGGHLGGVARATRESMLVLEAAGYDVVLVETVGVGQSEVAVAGMVDTFLMLQVARTGDMLQGIKRGILELADVIAITKADGDNEQAARVAARELSIAMKLITSDNDKRRAPVLTCSSYTGAGLDELWDTVEKHRAELESSGTLAPRRLAQQRDWLWNMVRDELMESLRTSPGVRQTAADVEARLADESLSALEGSQEILRAFAAAVPTMHWGDQTSLRLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHL4</accession>
    <name>A0A1Q2CHL4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cu+-exporting ATPase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Heavy metal transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_12955</name>
        <name evidence="4" type="ORF">SAMN05428934_10496</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12955"/>
    <dbReference type="EnsemblBacteria" id="AQP45602">
        <property type="protein sequence ID" value="AQP45602"/>
        <property type="gene ID" value="RPIT_12955"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY77657">
        <property type="protein sequence ID" value="SDY77657"/>
        <property type="gene ID" value="SAMN05428934_10496"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12955"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006825">
        <property type="term" value="P:copper ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000428">
        <property type="entry name" value="Cu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00944">
        <property type="entry name" value="CUEXPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMA" evidence="2">
        <location>
            <begin position="2"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY77657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="69" mass="7470" checksum="5C87EF180C649803" modified="2017-04-12" version="1">MITKYTVSGMTCGNCVSHVTEEVSEVEGVKNVNVTLEDGSMLVESDERVPFDSIIEAVREAGDYTVVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHN8</accession>
    <name>A0A1Q2CHN8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Monosaccharide ABC transporter membrane protein, CUT2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_12830</name>
        <name evidence="8" type="ORF">SAMN05428934_104121</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY78315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12830"/>
    <dbReference type="EnsemblBacteria" id="AQP45580">
        <property type="protein sequence ID" value="AQP45580"/>
        <property type="gene ID" value="RPIT_12830"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY78315">
        <property type="protein sequence ID" value="SDY78315"/>
        <property type="gene ID" value="SAMN05428934_104121"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12830"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY78315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="327" mass="33844" checksum="9B748404DDFCAC63" modified="2017-04-12" version="1">MNVGANAVDKPVSGVRSALSWEGTGLLAVLIIVFVLLSIWAPNFLTMANLLNVLQQAAFFGIVAFAMTLVIVSGEIDVSVGSSAALTSSLVGYMVVSMGVPMPLAALIALVVAIALGAFVGWIRHVFNVPTFIGTLALFLALRGAAHLVTNTFPIPIDSSEFFYWGTGRILGVPVAALYLVIAFVVVAFIANFTVFGRSVYAVGGNARTAQISGINVLKIRVIVMAISGFTAGITGLLQTAQLSSGNSNIAQGLEFDAIAAAVIGGTAMSGGKGSVVGTLIGVLFVAILLNGMVLLGLNPYFQQVVRGALVLFAVLINVVRTRRSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHR8</accession>
    <name>A0A1Q2CHR8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Extensin-like_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13315</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="AQP45668"/>
        <property type="gene ID" value="RPIT_13315"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13315"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009683">
        <property type="entry name" value="Extensin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06904">
        <property type="entry name" value="Extensin-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013338032" description="Extensin-like_C domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Extensin-like_C" evidence="2">
        <location>
            <begin position="108"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="252" mass="27716" checksum="82E6815BC8BF36AE" modified="2017-04-12" version="1">MVSRRALLLGAATVPLAGCSRLASTEPGPDWMPDRIGGCRTPDALTSFSTVGGAPLVYEVTGVAQSFRADPRFVELLDAWAADWVSLSGLGPLRRITTYGAFVDKCDSWHAAGRAFDFGVLEHDGGTVSCRYDQFGEDPAQLRRYWQLSASLAKWFTYTLTYRYNEQHHNHIHVDNGISGYDETGFAQRSRVQVMVVQGVVRHVFGLDAPFSGSYDGATRDAVREIQRSLGITDPLRRAPGWQAFLDAAVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHW4</accession>
    <name>A0A1Q2CHW4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Luciferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Probable oxidoreductase, LLM family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13245</name>
        <name evidence="3" type="ORF">SAMN05428934_10438</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY76048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13245"/>
    <dbReference type="EnsemblBacteria" id="AQP45655">
        <property type="protein sequence ID" value="AQP45655"/>
        <property type="gene ID" value="RPIT_13245"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY76048">
        <property type="protein sequence ID" value="SDY76048"/>
        <property type="gene ID" value="SAMN05428934_10438"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13245"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022290">
        <property type="entry name" value="CHP03858_lucif-like_mOase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03858">
        <property type="entry name" value="LLM_2I7G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
            <begin position="26"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY76048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="341" mass="37041" checksum="52CDFE3392A09623" modified="2017-04-12" version="1">MSFEFGIDTFGDVTEGPDGNLLPHDQVVRNVVDEGVLADEVGLDAIGIGEHHRDDFAVSAPDMLLAAIAARTGRIKLASAVTVLSSDDPVRVFERFSTLDAISAGRAEVVVGRGSFTESFPLFGYNLGDYEDLFEEKMAMFAQLRHGGRQSWEGQLTQSLDDVELYPTLANGPLKTWVAVGGSPQSVLRAAHYGLPLMLAIIGGPVDRFAPFADLHRRALDEMGKAPQPIGYHSYGFIGRTDQEARETLYQPWLAQTSRIGAERGWGRIDRAHFNNEADHGAMAVGSPETVARKIAHGLRALGATRFQLKVSTGRLSHEAILDTIGLYGTEVVPLVRDMLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI12</accession>
    <name>A0A1Q2CI12_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plasmid stabilization protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13465"/>
    <dbReference type="EnsemblBacteria" id="AQP45695">
        <property type="protein sequence ID" value="AQP45695"/>
        <property type="gene ID" value="RPIT_13465"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13465"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
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        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="89" mass="9863" checksum="509C116AAEB253C9" modified="2017-04-12" version="1">MYRYLASSASPPVGAEYVEAIVAQCEGLEVFPHRGTMRNDIRPGLRTSSYKKRAVIATFVDDEAEQTTILDVFHGGHDYDTILSGFDHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI25</accession>
    <name>A0A1Q2CI25_9ACTN</name>
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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                <person name="Schumann P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">RP1</strain>
        </source>
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    </reference>
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            <end position="308"/>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDZ12027.1"/>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="317" mass="34432" checksum="6D397DCC0507BA1B" modified="2017-04-12" version="1">MEITELGRSGLQVSRLAFGGCPMGGHGWGAVSRDDVGNAIQAALAHGLNFFDTADTYGLGEGERTLGKALKGRRDRAVIATKFGVRVEGGRTFYDNSPAWITKALEASLRRLQTDYVDLYQIHYRDGVTPLDDVVAALVDLQQQGKVRHIGLSNVGSSHASELAPHRGRFVSFQDEFSLASRSNEPDIQLLASDFGLSPLTWGSLGQGILSGKYGANSTFGPDDRRSRPIYVNFHGERLQRNLRIVEVLRQLSRDFGKSVPSVAIRWILDSLPGSVAIVGIKNVQQLKANLEALSWSLPLGARADLDAVSDYEGALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI78</accession>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Schumann P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ14700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14225"/>
    <dbReference type="EnsemblBacteria" id="AQP45817">
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        <property type="gene ID" value="RPIT_14225"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ14700">
        <property type="protein sequence ID" value="SDZ14700"/>
        <property type="gene ID" value="SAMN05428934_11227"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14225"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ14700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="266" mass="28026" checksum="68C1F774D77A817A" modified="2017-04-12" version="1">MAVVVLASATGSPGVTTTALGLALAWPRRVLVADCDRDPSQAVQAGYLRGMDHGGRGLMSLAHLHREGAPLDPEVWRHGLPLVEGGEIERRFLPGFATAGASRLFEHVWRPLGESFGALDTQGADVIVDAGRISTTGLPLGLLAVADTVILCVRSSLRSLAGARIHLTTLQEQLRSLPVPPPAALAVVGSGRPYSGAEIAAQFSLPVVVEPAWDPRGAEVLSDGGQEPRRFSDSPFMGRFRSDAKALSERIARTRQHTAVIAGVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIC6</accession>
    <name>A0A1Q2CIC6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major Facilitator Superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_14155</name>
        <name evidence="8" type="ORF">SAMN05428934_11212</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ14387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14155"/>
    <dbReference type="EnsemblBacteria" id="AQP45805">
        <property type="protein sequence ID" value="AQP45805"/>
        <property type="gene ID" value="RPIT_14155"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ14387">
        <property type="protein sequence ID" value="SDZ14387"/>
        <property type="gene ID" value="SAMN05428934_11212"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14155"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="318"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="380"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="456"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="23"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ14387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="481" mass="50712" checksum="93FC1734A9B5B173" modified="2017-04-12" version="1">MPTPNRNVITVEGTDRTFSRVRILFVLLMSMGMSLIAVSSVNVALPALEQGLDASSSDLQWVLTGYALAIGVTLIPAGRAGDVLGRGAFFVVGAAIFTIASLACGLAPTPLLLNLARIVQGIGAGLFSPQVTGMIQQYFSGGGRAKAFALLGVVISASVAVGPVLSGAIISALGEETGWRWAFFIYLPVGLAAVVLALLWFPFETERQLRNPGRARSRIDLDPVGTVLVVAIVLAVMYPFMARQPLAWTLLAVAPVLLWIWIRWERGYAESGREPIVDLTLFRYRSYRNGLMVSGAVFLGVTSTFAVLALFLQSGLGVSAIFAGLIGLPNAISSAISATVTARYVLSHGRQLVILAVVLLLTGTLLSLLVAWLIGAFGISFWWLSPTLVLNGLGMGIFGSANQTLSMQDIPPAHGGTASGIKQTIERITTALGNAAITGLFFVVVADVSWVSGIAAAYAAIAVCLVVAFGLGLMDRRQHAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIF8</accession>
    <name>A0A1Q2CIF8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="5 8">5.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_14805</name>
        <name evidence="11" type="ORF">SAMN05428934_10959</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="5 8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14805"/>
    <dbReference type="EnsemblBacteria" id="AQP45918">
        <property type="protein sequence ID" value="AQP45918"/>
        <property type="gene ID" value="RPIT_14805"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05704">
        <property type="protein sequence ID" value="SDZ05704"/>
        <property type="gene ID" value="SAMN05428934_10959"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14805"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05247">
        <property type="entry name" value="UDP_G4E_1_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 8" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="9">
        <location>
            <begin position="4"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP45918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDZ05704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="337" mass="36320" checksum="54DBDAAA77A5FF06" modified="2017-04-12" version="1">MRVLVTGGAGYIGSHTTLALLREGHDVLVVDDLSNSSEESLRRVADLAGREASFVEANVRDEEKLGAAFADFKPDAVIHFAGWKAVGESTEIPLTYYRENLGSTIALLETMAKHDCHRIVFSSSATVYGEMSEPPFTEDAQTGATNPYGRTKHMLEQILEDAAAADPKLAVAVLRYFNPIGADESGRIGEDPKGIPNNLLPFVAQVAAGRREKLMVFGDDYNTADGTGARDYIHVVDLAAGHLAALEYLTGNSGYHVWNLGTGNPSTVLEIVKAFEEASGKEIPYEVVARRPGDVAASYANVDKAHRELGWSAEKTVADACADTYRWQSNNPNGFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIP3</accession>
    <name>A0A1Q2CIP3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">POTRA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_04040</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04040"/>
    <dbReference type="EnsemblBacteria" id="AQP46008">
        <property type="protein sequence ID" value="AQP46008"/>
        <property type="gene ID" value="RPIT_04040"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04040"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005548">
        <property type="entry name" value="Cell_div_FtsQ/DivIB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034746">
        <property type="entry name" value="POTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013685">
        <property type="entry name" value="POTRA_FtsQ_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03799">
        <property type="entry name" value="FtsQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08478">
        <property type="entry name" value="POTRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51779">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="8">
        <location>
            <begin position="48"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP46008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="237" mass="26013" checksum="823456AA589F6D51" modified="2017-04-12" version="1">MTPGRFVQALQSKRRAAKRRTLILWGGVAVLVVGAAVGTWLLFFSPVFAAQQVSTSGLELLTEEQVAQAAAVPVGEPLLRISTQSAEERVRELAPVDEVDVVRRFPDAIEIIVTERRMQYQRERGGQFEWIDEDGVVFHSTAEPSSGALLARSDTEEQRLLADIATVARHVPGEIRPEVEAIQADAVDQISLLLPEGRTVVWGSAEESELKAQVLEALLEIDATVFDVSAPRHPTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIS1</accession>
    <name>A0A1Q2CIS1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_04210</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04210"/>
    <dbReference type="EnsemblBacteria" id="AQP46011">
        <property type="protein sequence ID" value="AQP46011"/>
        <property type="gene ID" value="RPIT_04210"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04210"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004365">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43148">
        <property type="entry name" value="PTHR43148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="9">
        <location>
            <begin position="3"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="152"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="211"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="12"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="6">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP46011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="331" mass="35650" checksum="C5803B4E1D88750A" modified="2017-04-12" version="1">MTVKVAINGFGRIGRNYFRALVASGADLEVVAVNDLTDNKTLAHLLKYDSILGRFDGEITYDDDAIKIDGKEIKAFAEKDPAALPWADLGVDIVVESTGFFTDATKAQAHIDAGAKKVLISAPAKNEDITIVMGVNDDKYDPAAHNIISNASCTTNCLAPMAKALNDGIGIVKGLMTTIHAYTQDQNLQDGPHKDLRRSRAAALNMVPTTTGAAKAVSLVLPELKGKLDGYAMRVPTPTGSATDLTFEASRETSVEEINEIIKNAADGKVLVYTEDEIVSKDIETDPASCIFDAKLTKVIGNQVKVLGWYDNEWGYSNRLVDLTVMVGEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIU4</accession>
    <name>A0A1Q2CIU4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_01850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01850"/>
    <dbReference type="EnsemblBacteria" id="AQP45970">
        <property type="protein sequence ID" value="AQP45970"/>
        <property type="gene ID" value="RPIT_01850"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01850"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014487">
        <property type="entry name" value="DUF3151"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11349">
        <property type="entry name" value="DUF3151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017349">
        <property type="entry name" value="UCP017349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="135" mass="14811" checksum="D8C7D3F300C2E34B" modified="2017-04-12" version="1">MASDVVVHLPEDPALAAISEKGREHFLEVVAAYPESSLCWALLAETCLADDDLGSSLAAYAYARTGYHRGLDTLRRNGWKGSGAVPWEHEPNRGFLRALWALSVAAGRIGESEEQQRCAQFLRDSSETAYQELTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIW2</accession>
    <name>A0A1Q2CIW2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PlsC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_07135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07135"/>
    <dbReference type="EnsemblBacteria" id="AQP46066">
        <property type="protein sequence ID" value="AQP46066"/>
        <property type="gene ID" value="RPIT_07135"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07135"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PlsC" evidence="2">
        <location>
            <begin position="30"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="238" mass="26249" checksum="A56D4B077A2AA2BB" modified="2017-04-12" version="1">MIAHFARLVNPLVSRRRWAGQEHIPKTGGVILVANHTSNYDPLALGEFIIWAGRWPRFLGKSEIWNVPGLGWFARKCEQIPVFRNTDRAINSLVHAEEALLTKHHAVAIYPEGTITADPDVWPMTGRRGAAQLALKTGVPVVPLVAVGPHRVLGQKNLEFGKLLGGRKPVSVMARPALDLSAYEGAEPTKEVLDDITELILDTLTEMVAEIRGEQPPPEGRYDMRLGRRVGDGAVRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ66</accession>
    <name>A0A1Q2CJ66_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cell division protein CrgA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">crgA</name>
        <name evidence="4" type="ORF">RPIT_12725</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in cell division.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CrgA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12725"/>
    <dbReference type="EnsemblBacteria" id="AQP46157">
        <property type="protein sequence ID" value="AQP46157"/>
        <property type="gene ID" value="RPIT_12725"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12725"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00631">
        <property type="entry name" value="CrgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009619">
        <property type="entry name" value="CrgA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06781">
        <property type="entry name" value="CrgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP46157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="94" mass="10602" checksum="3EDB6F202C98C9E0" modified="2017-04-12" version="1">MPESRSRKQAEEKKKLKSKAELAEQRSEYSRLAPANRNWVPAVFIPMGLLGVAWMVTYNLAGDRIGFMQSIGDWNVVIGLGLIVASFAFMTLWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJC3</accession>
    <name>A0A1Q2CJC3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LMWPc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_13980</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the low molecular weight phosphotyrosine protein phosphatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13980"/>
    <dbReference type="EnsemblBacteria" id="AQP46183">
        <property type="protein sequence ID" value="AQP46183"/>
        <property type="gene ID" value="RPIT_13980"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13980"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017867">
        <property type="entry name" value="Tyr_phospatase_low_mol_wt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00719">
        <property type="entry name" value="LMWPTPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LMWPc" evidence="3">
        <location>
            <begin position="2"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP46183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="175" mass="18792" checksum="527197ADC5E6C731" modified="2017-04-12" version="1">MLFVCTANICRSAYAEAAARASATEEIAFMSAGTHALVGEGMDPPMAAELRGIGDAAAHRAQQLALPLAQEADLILTMGAQHRRYILDEWPALAHKTFVIGHAARVLAELPPEVSLEGVADHLWRNRTVQKGDEVADPYRRGPEAASVAARQIDANLAVIVEALSRLSLASRHRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBK7</accession>
    <name>A0A1Q2CBK7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00535"/>
    <dbReference type="EnsemblBacteria" id="AQP43489">
        <property type="protein sequence ID" value="AQP43489"/>
        <property type="gene ID" value="RPIT_00535"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00535"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="373" mass="40434" checksum="D9D8C7922432B7F6" modified="2017-04-12" version="1">MSGTVGIVTTGHDVADARLHRTVAALRRAGCDVWVRGLGDPAKGPAGARISTAPAAGKLRRGLRALVWPLRGKCDVLITIDPDTSLTAWLRPGRWVADVHEDYRELLRDRSWVPAPLLRVLRAAVSALNWMISRADLVLVADDHVPPMAPRRYVMRNEPDVTVLPAMPAHTSERSAPFTAIYIGDNRESRGLKTMVEAVAGTADDEGFWRLDLVGPVAAGDREWFEERMSRPDARHVTFHDRLPPGEAWRIAERADVGLCLLADTPAFRDAMPSKVYEYLAMGLPTLATPLPRVQALLDEVGAGMIVGSATAATDALRRFATDDAERARLVANARAAGQALRDKPSTYDEAARRIAALCTSPSPGSGPSLDPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBP4</accession>
    <name>A0A1Q2CBP4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CubicO group peptidase, beta-lactamase class C family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00790</name>
        <name evidence="4" type="ORF">SAMN05428934_105111</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00790"/>
    <dbReference type="EnsemblBacteria" id="AQP43533">
        <property type="protein sequence ID" value="AQP43533"/>
        <property type="gene ID" value="RPIT_00790"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86371">
        <property type="protein sequence ID" value="SDY86371"/>
        <property type="gene ID" value="SAMN05428934_105111"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00790"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="157"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY86371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="445" mass="47749" checksum="C797CB07FE4CC4E5" modified="2017-04-12" version="1">MRERRRLWPRVLVGVIVVIIIALLGGYWYARPLLLTGTGYAAHNECALRTIGGRSNVEADLPSNPLVPYLRTTDDEASVRASVLGVLAVQRAHAAEGYGCTVGAQAPELPEPTRVLDSNPVLTRALVPPPADLESAINRAFGDDLDHDAKAALGTRAVVVLHEGRLVAERYADGFTEFSPQLGWSMAKSATNLLVGRLVHDGVVDIDEPLEMGWADDASGAITLDDLLRMRSGLAWDETYDLGTPITSMLYLQRDMGAFAAGQPQEHPVGTVQEYSSGSTNIVCKALVQATGQGADLPRSELFAPLGLSRAVWEPDGAGVPVCSSYLWATPREFAVLGQFALDDGVVGGERLLPEGWIAESTTAEPVVEAEDSGYGSSWWVNLRPDGTLSKPNLPADAYWMQGHDGQRTYVVPSADLVVVRMGFSPDAPDLRADQLVIDLVSVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBR7</accession>
    <name>A0A1Q2CBR7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00865</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43548">
        <property type="protein sequence ID" value="AQP43548"/>
        <property type="gene ID" value="RPIT_00865"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00865"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="282" mass="31536" checksum="C8DF01E2A1C21F27" modified="2017-04-12" version="1">MRRVRKPKEPASLSDVKTLDERQAALDFYAAWDGSAKYDGFKAYKNPDVRAALEEAFGGKCAYCETSYAATQPVAIEHYRPKGEVKIGRKRVPPGYYWLASEWTNLLPSCTDCNSPRGQDLPNQPKTVTAGKANAFPLASESTRATTPGSERTEKRLLLHPYLDYPEKHLEFVWGTGTVDDGWVRPLRGSRKGAATIEVCALQRRGLRAARRDRLLDLIAHLESVAEAQSNVVRRPDDPELLTQLERRLAEVSRFVADHAPYSAMCRQVVAAYRQKLFGGPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBU6</accession>
    <name>A0A1Q2CBU6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01040</name>
        <name evidence="4" type="ORF">SAMN05428934_105159</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01040"/>
    <dbReference type="EnsemblBacteria" id="AQP43579">
        <property type="protein sequence ID" value="AQP43579"/>
        <property type="gene ID" value="RPIT_01040"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87675">
        <property type="protein sequence ID" value="SDY87675"/>
        <property type="gene ID" value="SAMN05428934_105159"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01040"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="2">
        <location>
            <begin position="209"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY87675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="413" mass="44218" checksum="5E3EC407A8BC5811" modified="2017-04-12" version="1">MNPGPRPAAASDRIHTHPQRITAALLVGYLLLAGGFAYLSLESSLRTPPAGILVLGTAAIATIVIRHRLPTLAFAAALALLPLTFALGTGAEAVLIVPALFRAGAELIPRRAWGAFSVSAAVGIVAAVVLAFRLRLGPPILGLAPRAAYDEWPTDWISAATVYLVVALITTLIGINVGHRRRHISSLVERAEQMERERDQQASIARALERERIAREMHDVIAHSLAVMIALADGADAATSSSRPDEAHRAIKRVAETGRRTLGEVRLLLGAVRRNQDPGQPSVPTTLGIDDLPALADGFRTAGLPVRLEVSGHLTAHSSLAGLTTYRIVQESLTNVLRHARDVRDVHVQVQLREREAVIVVEDTSAPVSDEIVDGRGLVGIRERAAFYDGDVTAGPRAAGGWRVEVRLPMEEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBV0</accession>
    <name>A0A1Q2CBV0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycerol 3-phosphate dehydrogenase (Quinone) subunit A</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">sn-glycerol-3-phosphate dehydrogenase subunit A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_01120</name>
        <name evidence="6" type="ORF">SAMN05428934_105175</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY88104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01120"/>
    <dbReference type="EnsemblBacteria" id="AQP43593">
        <property type="protein sequence ID" value="AQP43593"/>
        <property type="gene ID" value="RPIT_01120"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY88104">
        <property type="protein sequence ID" value="SDY88104"/>
        <property type="gene ID" value="SAMN05428934_105175"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01120"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004368">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046174">
        <property type="term" value="P:polyol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041854">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000447">
        <property type="entry name" value="G3P_DH_FAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017752">
        <property type="entry name" value="G3P_DH_GlpA_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985">
        <property type="entry name" value="PTHR11985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01001">
        <property type="entry name" value="FADG3PDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03377">
        <property type="entry name" value="glycerol3P_GlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="4">
        <location>
            <begin position="7"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY88104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="525" mass="57553" checksum="BA448DC4AC3A6ECE" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBW4</accession>
    <name>A0A1Q2CBW4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01150</name>
        <name evidence="3" type="ORF">SAMN05428934_105180</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY88226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43599">
        <property type="protein sequence ID" value="AQP43599"/>
        <property type="gene ID" value="RPIT_01150"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY88226">
        <property type="protein sequence ID" value="SDY88226"/>
        <property type="gene ID" value="SAMN05428934_105180"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01150"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY88226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="129" mass="13880" checksum="C11C22753CD12573" modified="2017-04-12" version="1">MPAYSDAPLPVGLDALVGMGMNRVKLAIAVALAEHGCRLSTPELVAALGERVAGTTIARNLNELEDHGYVTGDVPRDDRRRRRTHWTLNHAKLHADLQALIQATTPSVETPTTSDRAGGVHSGPEREPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBX2</accession>
    <name>A0A1Q2CBX2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pyridoxal 5'-phosphate synthase subunit PdxT</fullName>
            <ecNumber evidence="4">4.3.3.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Pdx2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Pyridoxal 5'-phosphate synthase glutaminase subunit</fullName>
            <ecNumber evidence="4">3.5.1.2</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pdxT</name>
        <name evidence="7" type="ORF">RPIT_01230</name>
        <name evidence="8" type="ORF">SAMN05428934_105195</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = H(+) + 3 H2O + L-glutamate + phosphate + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:31507"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="4.3.3.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the glutaminase PdxT/SNO family.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.6" evidence="4"/>
    <dbReference type="EC" id="3.5.1.2" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY88551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01230"/>
    <dbReference type="EnsemblBacteria" id="AQP43608">
        <property type="protein sequence ID" value="AQP43608"/>
        <property type="gene ID" value="RPIT_01230"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY88551">
        <property type="protein sequence ID" value="SDY88551"/>
        <property type="gene ID" value="SAMN05428934_105195"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01230"/>
    <dbReference type="UniPathway" id="UPA00245"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036381">
        <property type="term" value="F:pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006543">
        <property type="term" value="P:glutamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01749">
        <property type="entry name" value="GATase1_PB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01615">
        <property type="entry name" value="PdxT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002161">
        <property type="entry name" value="PdxT/SNO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021196">
        <property type="entry name" value="PdxT/SNO_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31559">
        <property type="entry name" value="PTHR31559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01174">
        <property type="entry name" value="SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005639">
        <property type="entry name" value="Glut_amidoT_SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03800">
        <property type="entry name" value="PLP_synth_Pdx2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01236">
        <property type="entry name" value="PDXT_SNO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51130">
        <property type="entry name" value="PDXT_SNO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="L-glutamine binding" evidence="4 6">
        <location>
            <begin position="47"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-glutamine binding" evidence="4 6">
        <location>
            <begin position="137"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4 5">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4 5">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4 5">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005639-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR005639-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY88551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="193" mass="19894" checksum="1BF0421E25F544F3" modified="2017-04-12" version="1">MVTVGVVALQGAVREHARAVQEVGGRARFVRTPGDLAGLDGLILPGGESTVMARLARGTGLFPAIRAALDRGLPVLGTCAGLILLADDVADPGALEGLETVGGLDVRVRRNAYGSQLASGVVPVTAANRTTFSGVFIRAPRIESVGPGVVVLATRAGEPVAVRQGSVTACAFHPELAEDRRFHEWLLSSTAPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBZ8</accession>
    <name>A0A1Q2CBZ8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase small domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01445</name>
        <name evidence="3" type="ORF">SAMN05428934_10837</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01445"/>
    <dbReference type="EnsemblBacteria" id="AQP43643">
        <property type="protein sequence ID" value="AQP43643"/>
        <property type="gene ID" value="RPIT_01445"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01644">
        <property type="protein sequence ID" value="SDZ01644"/>
        <property type="gene ID" value="SAMN05428934_10837"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01445"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044260">
        <property type="term" value="P:cellular macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043412">
        <property type="term" value="P:macromolecule modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTS" evidence="1">
        <location>
            <begin position="141"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ01644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="489" mass="53126" checksum="38BA5F89B5946310" modified="2017-04-12" version="1">MHVTDVDAIQLRNHLDGAGFTVEGVLERIGEAGQDGLRRNCTVPADVALNGATDPLASLIRLFILQQKVPADQLREVLDLGQLGRAGYLDVGVEVRALVDIRPYGSPDDGATGWVVADPTPGLDHSMEPTRPDYVLGVSPASSTLAQITMRSEVSSALDLGTGCGVQSLHLSRHCGRVVATDVNGRALDLAALTADLNQVDVDLRLGSLYEPVAGERYDLIVSNPPFVMSPPRAEAETLAYREANFEGDSLVERLVRGAGNHLNPGGSLQLLTNWAVLDEPWQERLAAWIPQECDAWVIERERLDVYSYIEMWLTDAGLAGTPGWRTAYDEWLAYFNRLGIRSVGMGWILITRADRPEPFRRFESWPHAVAQPVGGVFERHRAAVDAHLLPVDELLDTRPRLIDVDEETVGRPGAGDPEHIVFRQRVGLLRAIRADTTLAAVLGALDGDLTLGQVTAAVAQVLDEDPAEVAAAVIPEVRAALLDQMLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC35</accession>
    <name>A0A1Q2CC35_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lsr2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01610</name>
        <name evidence="4" type="ORF">SAMN05428934_10870</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01610"/>
    <dbReference type="EnsemblBacteria" id="AQP43666">
        <property type="protein sequence ID" value="AQP43666"/>
        <property type="gene ID" value="RPIT_01610"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02260">
        <property type="protein sequence ID" value="SDZ02260"/>
        <property type="gene ID" value="SAMN05428934_10870"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01610"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024412">
        <property type="entry name" value="Lsr2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042261">
        <property type="entry name" value="Lsr2_dimerization"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11774">
        <property type="entry name" value="Lsr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="54"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ02260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="108" mass="11838" checksum="30C99E104BE26DB5" modified="2017-04-12" version="1">MARQIRVILTDDIDGSEGAQTVEFALAGKNYSIDLNETNRKKLETALAPFIEKADKVSRGRTQRRSSSSSARSGNTSAVRSWARGEGYEVSDRGRVPAHIVEAYEAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC45</accession>
    <name>A0A1Q2CC45_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Iron ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Thiamine transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_01630</name>
        <name evidence="7" type="ORF">SAMN05428934_10874</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01630"/>
    <dbReference type="EnsemblBacteria" id="AQP43670">
        <property type="protein sequence ID" value="AQP43670"/>
        <property type="gene ID" value="RPIT_01630"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02331">
        <property type="protein sequence ID" value="SDZ02331"/>
        <property type="gene ID" value="SAMN05428934_10874"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01630"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="341"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="374"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="411"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="514"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="59"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="337"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ02331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="546" mass="58307" checksum="5012ED207667FF2D" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC80</accession>
    <name>A0A1Q2CC80_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thiol peroxidase</fullName>
            <shortName evidence="2">Tpx</shortName>
            <ecNumber evidence="2">1.11.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peroxiredoxin tpx</fullName>
            <shortName evidence="2">Prx</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Thioredoxin peroxidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Thioredoxin-dependent peroxiredoxin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tpx</name>
        <name evidence="4" type="ORF">RPIT_01815</name>
        <name evidence="5" type="ORF">SAMN05428934_108111</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[thioredoxin]-dithiol + a hydroperoxide = [thioredoxin]-disulfide + an alcohol + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxiredoxin family. Tpx subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ03069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01815"/>
    <dbReference type="EnsemblBacteria" id="AQP43700">
        <property type="protein sequence ID" value="AQP43700"/>
        <property type="gene ID" value="RPIT_01815"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ03069">
        <property type="protein sequence ID" value="SDZ03069"/>
        <property type="gene ID" value="SAMN05428934_108111"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01815"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03014">
        <property type="entry name" value="PRX_Atyp2cys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00269">
        <property type="entry name" value="Tpx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002065">
        <property type="entry name" value="TPX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018219">
        <property type="entry name" value="Tpx_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01265">
        <property type="entry name" value="TPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 4" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="18"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="2">
        <location>
            <begin position="60"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ03069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="165" mass="17417" checksum="1D0A3EF6225A4CA8" modified="2017-04-12" version="1">MADIKFHGNPVHSVGTLPEVGSTAPDFEVTGTDLSPVKLSDFAGQKIVLNIFPSVDTGVCANSVRAFNEKAAGLEGTTVLCISRDLPFALGRFCGAEGIDNVVVASDFRTDLGEKYGVTFTDGPLEGLLSRSVVVIDTDGKVVYTQQVEETTTEPDYDEALAALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC96</accession>
    <name>A0A1Q2CC96_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43732">
        <property type="protein sequence ID" value="AQP43732"/>
        <property type="gene ID" value="RPIT_02000"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02000"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="146" mass="16123" checksum="70A99062DE5AB845" modified="2017-04-12" version="1">MRGGAEVPTTVIPEAINVAMELEAVHFEDEFLTDEKIHAPNAVQHYLHSKSDPGAPQQVTNHGLESRLYGPIRHRDRRPLPRGALGQNVLQFVVGQKPTATDVVRCDHSVNGWMAGEGRRERSGERHHQPPLGPSEPTPAITPVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCA1</accession>
    <name>A0A1Q2CCA1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3-oxoacyl-ACP reductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">3-oxoacyl-[acyl-carrier protein] reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_01930</name>
        <name evidence="2" type="ORF">SAMN05428934_11618</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000016">
        <property type="protein sequence ID" value="SDZ20455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01930"/>
    <dbReference type="EnsemblBacteria" id="AQP43720">
        <property type="protein sequence ID" value="AQP43720"/>
        <property type="gene ID" value="RPIT_01930"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ20455">
        <property type="protein sequence ID" value="SDZ20455"/>
        <property type="gene ID" value="SAMN05428934_11618"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01930"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ20455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="463" mass="48047" checksum="C4B25AB7CD2F04D0" modified="2017-04-12" version="1">MSILEMIYGTPAGKFVAKKAGLSEPPTLRRGRTMPSGPVALAELGGGGLAAECLQLLGVSTVEPLLDVADARTKDDKGRMQPPRYQTRPGAVVVDATGVRRITELEGIRQALRPAMRGLEKSGRIIILATDATGVEGLEAKAVAQGIDGINRTVGKELRDGSTSNLVFVKPGTTAADLASTLSFLLEGRSAFVSGQAWRVGPSKDPHDLTDRPFDGRVVVVTGAARGIGAAIARTFSRDGATVVAVDIPAAGDALAKVANEIGGSALQLDITAADAGQKIAGHVARVHGAQKRIWAIVHNAGITRDKMLANLDEKLWASVLDVNLAAEMRINDFLLSNPDAPGGLDTSARIVGIASTSGVAGNKGQTNYAASKAGVMGLVWAMKDELADRPITVNAVAPGFIETEMTGAIPFVQREIFRRTNSLNQGGKPVDVAETLAYLCGPASGGVDGQVIRVCGQNLVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCC3</accession>
    <name>A0A1Q2CCC3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized membrane protein YkoI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_02080</name>
        <name evidence="5" type="ORF">SAMN05428934_10113</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY22686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02080"/>
    <dbReference type="EnsemblBacteria" id="AQP43747">
        <property type="protein sequence ID" value="AQP43747"/>
        <property type="gene ID" value="RPIT_02080"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY22686">
        <property type="protein sequence ID" value="SDY22686"/>
        <property type="gene ID" value="SAMN05428934_10113"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02080"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025711">
        <property type="entry name" value="PepSY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03413">
        <property type="entry name" value="PepSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544414" evidence="2">
        <location>
            <begin position="23"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="PepSY" evidence="3">
        <location>
            <begin position="157"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY22686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="213" mass="21262" checksum="397DA46E9621543B" modified="2017-04-12" version="1">MNIRRVSLSLIASSALAVVACGASEGPTGDTSPITPGPVVATTSSPDGGVGDGASPTSSSPAAAASEPSSAPVQSTGEGAEEINASALQAVSTAEESAGGAAVKLDDEDFDRAWEIDVLVGNRVVEVKVNREGTEVLETADDDALDDGETAQPGDLIAAAEAALGHSPGVIDDVELETDDGVLYWSVELDGTDGGDDVELRVDTRTGAVTPEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCG7</accession>
    <name>A0A1Q2CCG7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transposase InsO and inactivated derivatives</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02330</name>
        <name evidence="3" type="ORF">SAMN05428934_10166</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY24262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43796">
        <property type="protein sequence ID" value="AQP43796"/>
        <property type="gene ID" value="RPIT_02330"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY24262">
        <property type="protein sequence ID" value="SDY24262"/>
        <property type="gene ID" value="SAMN05428934_10166"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02330"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025948">
        <property type="entry name" value="HTH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13276">
        <property type="entry name" value="HTH_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13333">
        <property type="entry name" value="rve_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="126"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY24262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="296" mass="32683" checksum="382A5AD42980D626" modified="2017-04-12" version="1">MTDMFTLIHAEKATHSVELMTRLLDVSRAGYYSWVKRGDTPGPAATRRAEVTAAVIDSHTASNGVNGHRRVRADLTADGVPASEGMVRSIMRQAGIAGIQPRTKKRTTIPADDAEQRPDLVKRDFTSDTPGTKLVGDITYLRTGKGWLFLATVIDLHSRMVVGWAMAEHMRTELISAALRMAHTHGHLAPGAIFHSDRGSQYTSADYAAVASQLGVQLSVGRTGSCHDNAVAESWFSMLKNEMYHRHRFATRAQARLHVMQYIEVFYNRRRRHSTLDYQTPAAVHAAHQPQTAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCL4</accession>
    <name>A0A1Q2CCL4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Site-specific recombinase XerD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_02275</name>
        <name evidence="7" type="ORF">SAMN05428934_10154</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY23911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43785">
        <property type="protein sequence ID" value="AQP43785"/>
        <property type="gene ID" value="RPIT_02275"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY23911">
        <property type="protein sequence ID" value="SDY23911"/>
        <property type="gene ID" value="SAMN05428934_10154"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02275"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="5">
        <location>
            <begin position="7"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="117"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY23911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="323" mass="35329" checksum="BC64688E9B48AEF2" modified="2017-04-12" version="1">MLLPEDLSLDAAEAAFASASRASSTLRGYRSDWTEFVTWCRDNHHTALPATDIAISRYISVLATAGAKVGTISRRLSTIRFAHKVRNHPDPTQTARVIAVWEGIRRQLGAPPDQARPLMPPLLLDVVDACPAMTKWKTRDDEPSLSGIRDRVLLLVGFVSALRASELAALEVDQIKPHERGLVIELTRSKTNQTGDLELVVLPWGARQDYCPVTALRHWLTVAGITEGLVFRSVSKGNRVSARGLTPDGLSRLITQAVTRAGLDATGFSAHSLRAGFVTYAAKRGATSLQIARQTRHKDLASIGIYTRIEDAWEENAATQLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCM7</accession>
    <name>A0A1Q2CCM7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_02765</name>
        <name evidence="2" type="ORF">SAMN05428934_101153</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY26837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02765"/>
    <dbReference type="EnsemblBacteria" id="AQP43869">
        <property type="protein sequence ID" value="AQP43869"/>
        <property type="gene ID" value="RPIT_02765"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY26837">
        <property type="protein sequence ID" value="SDY26837"/>
        <property type="gene ID" value="SAMN05428934_101153"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02765"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY26837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="293" mass="31209" checksum="B0E9A84A18340100" modified="2017-04-12" version="1">MNVRKTTAKLAERAALGGMKAGFRLGERLAPRLTARAASALWFRVPPAPPPTKRDRGVRPGERLDIAVNGRPIAAYSWGEGPTVLLVHGWSGWWQQLGVYVEPLVAAGHRVVASDAPAHGDSPEGIFGRGRSGMPELKDAIDAVAQSVGEVHGLVAHSGGAMAASLAVAEGLDVARVAFIAPSVLLDDILELLGGRLDWGPRTVGEMLAALERDYGLHAADFDVPAVLGRRDLPFPRALFVHDEDDTETPVAGSDVLAGSWPGARVHRTSGLGHYKVLWAEPVVREVTEFLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD24</accession>
    <name>A0A1Q2CD24_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_03410</name>
        <name evidence="5" type="ORF">SAMN05428934_101282</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03410"/>
    <dbReference type="EnsemblBacteria" id="AQP43980">
        <property type="protein sequence ID" value="AQP43980"/>
        <property type="gene ID" value="RPIT_03410"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30812">
        <property type="protein sequence ID" value="SDY30812"/>
        <property type="gene ID" value="SAMN05428934_101282"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03410"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043968">
        <property type="entry name" value="SGNH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19040">
        <property type="entry name" value="SGNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="375"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl_transf_3" evidence="2">
        <location>
            <begin position="12"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH" evidence="3">
        <location>
            <begin position="399"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY30812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="639" mass="70182" checksum="5825174A651B93EC" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD32</accession>
    <name>A0A1Q2CD32_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_03730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03730"/>
    <dbReference type="EnsemblBacteria" id="AQP44033">
        <property type="protein sequence ID" value="AQP44033"/>
        <property type="gene ID" value="RPIT_03730"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03730"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="138" mass="15020" checksum="9229E6ACACAFA36C" modified="2017-04-12" version="1">MTNMSEAPAKVLVFSDDRNVREQIRLTLGRKVASDLPDIEVFEVATQGALLRALDTDLGYALMIFDGNAQPSGGFGLAHQVKEEYADSPPIMLLISREADAWLATWARAEAVAPFPIDPVTMPQQAANLIRARLAQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD55</accession>
    <name>A0A1Q2CD55_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_03810</name>
        <name evidence="9" type="ORF">SAMN05428934_101364</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY33181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03810"/>
    <dbReference type="EnsemblBacteria" id="AQP44048">
        <property type="protein sequence ID" value="AQP44048"/>
        <property type="gene ID" value="RPIT_03810"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY33181">
        <property type="protein sequence ID" value="SDY33181"/>
        <property type="gene ID" value="SAMN05428934_101364"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03810"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005543">
        <property type="entry name" value="PASTA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03793">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="4"/>
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        <property type="entry name" value="Pkinase"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_ST"/>
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    </dbReference>
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    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="398"/>
            <end position="419"/>
        </location>
    </feature>
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            <begin position="17"/>
            <end position="288"/>
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            <end position="386"/>
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    </feature>
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            <begin position="332"/>
            <end position="350"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
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            <dbReference type="PROSITE" id="PS51178"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP44048.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY33181.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="686" mass="74304" checksum="C44ED817E9BF542C" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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            <authorList>
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                <person name="Singh P."/>
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                <person name="Lal R."/>
            </authorList>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="12 14">RP1T</strain>
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            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
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            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H2O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate</text>
            <dbReference type="Rhea" id="RHEA:23596"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
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            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="1.1.1.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="similarity">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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            <end position="424"/>
        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
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            <position position="35"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
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        </ligand>
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            <position position="87"/>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
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        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
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        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
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        <ligand>
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        <ligand>
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        </ligand>
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        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
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        <ligand>
            <name>substrate</name>
        </ligand>
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        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
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            <dbReference type="ARBA" id="ARBA00000874"/>
        </source>
    </evidence>
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        </source>
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    </evidence>
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            <dbReference type="EMBL" id="SDY33653.1"/>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="protein sequence ID" value="SDY33155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="AQP44047"/>
        <property type="gene ID" value="RPIT_03805"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY33155">
        <property type="protein sequence ID" value="SDY33155"/>
        <property type="gene ID" value="SAMN05428934_101363"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03805"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY33155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="367" mass="41328" checksum="A666BE03F0B7156A" modified="2017-04-12" version="1">MPDFMIIVLIVLAVVAAGFAVWGVLRYRYVKSLRDKGWTFITSPDISIAYGLNRPPFGVGFQRSVDDQIVGAAPDGTPFSAFRYRSSEWSTSGYVVAMPLGRSLPPTEITASGPWRVQVDHAWIVLVEAPKDAESLERAIVELAELRGGVLASSGPDVIGPPPPPGLSFHERPWWRYVPRDDSFLDYVSHTRGGRNHQAHDIVHSENAGLPFVRLRHDWETTRTVRDSEGRTRTEVDHHSEVLCEFRAAFPFRPLSVNWGWLGKTQKFELEAFNDRCKVRAPDARFASHVIHQRQMDYLLSLGRPSFTIEADGRILVGDARGWEPTDIDRADQLLRGFFARVPDYVWKELGAWPRPIPELEPGPAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDE4</accession>
    <name>A0A1Q2CDE4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fe-S cluster assembly protein SufD</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Iron-regulated ABC transporter permease protein SufD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_04345</name>
        <name evidence="2" type="ORF">SAMN05428934_101474</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY36242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04345"/>
    <dbReference type="EnsemblBacteria" id="AQP44138">
        <property type="protein sequence ID" value="AQP44138"/>
        <property type="gene ID" value="RPIT_04345"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY36242">
        <property type="protein sequence ID" value="SDY36242"/>
        <property type="gene ID" value="SAMN05428934_101474"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04345"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011542">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43575">
        <property type="entry name" value="PTHR43575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01981">
        <property type="entry name" value="sufD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY36242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="393" mass="42679" checksum="8590DD054417C00D" modified="2017-04-12" version="1">MTTITTEAPNVAGAIETVESHLHPTPSWDAASHPMPTGREEIWRFTPLKRFKTLLAEGGEVGTLDWSADLPEGVTVENITAEQARALAVEAPSDRISAFAARDAKHRTHINVPANAELGEPVVFTATGRGGEARDQVIITVGAHARATIVLRYTGQAHYAEKTDVIVGDGAQLNIVTLQDWQDGSVHGGQRSVQIGRDAHVKTVTASLGGDIRLQENSRYGGPGGELESYGLYFVDAGQHVQHRLFVDHNAPHTKSNVDYRGALQGKGAHSVWIGDVLIRKVAEGIETYESNKNLVLTDGCQADSVPNLEIETGEIAGAGHSSSTGRFDDQQLFYLMSRGIDEPEARRLVAHGFFIDIIRRIGVPEIEDKLLAEIERELEIVHGSTRTKADEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDH1</accession>
    <name>A0A1Q2CDH1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)</fullName>
            <ecNumber evidence="4">1.17.7.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ispG</name>
        <name evidence="5" type="ORF">RPIT_04545</name>
        <name evidence="6" type="ORF">SAMN05428934_101515</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + H2O + oxidized [flavodoxin] = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + reduced [flavodoxin]</text>
            <dbReference type="Rhea" id="RHEA:43604"/>
            <dbReference type="Rhea" id="RHEA-COMP:10622"/>
            <dbReference type="Rhea" id="RHEA-COMP:10623"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:58483"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="4">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 5/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the IspG family.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.3" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04545"/>
    <dbReference type="EnsemblBacteria" id="AQP44172">
        <property type="protein sequence ID" value="AQP44172"/>
        <property type="gene ID" value="RPIT_04545"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37268">
        <property type="protein sequence ID" value="SDY37268"/>
        <property type="gene ID" value="SAMN05428934_101515"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04545"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00096"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046429">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00159">
        <property type="entry name" value="IspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016425">
        <property type="entry name" value="IspG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004588">
        <property type="entry name" value="IspG_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30454">
        <property type="entry name" value="PTHR30454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04551">
        <property type="entry name" value="GcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004640">
        <property type="entry name" value="IspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00612">
        <property type="entry name" value="ispG_gcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 4" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY37268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="380" mass="40040" checksum="50762CABD3C3B0E5" modified="2017-04-12" version="1">MSVKLGMPAAPAPTLAPRRPTRKIQVGKVAVGGDAPISVQSMTTTKTTDINATLQQIAELTATGCDIVRVAVPSQDDAEVLPIIAMKSQIPVIADIHFQPKYVFAAIDAGCAAVRVNPGNIKQFDDKVAEIAKAAGDAGVSLRIGVNAGSLDKRLLAKYGAPTAEALVESALWEASLFEEVGFYDFKISVKHNDPVVMVRAYELLSEKCQYPLHLGVTEAGPAFQGTIKSSVAFGALLSQGIGDTIRVSLSAPPAEEVKVGLKILESLNLRPRKLDIVSCPSCGRAQVDVYTLAEQVTKGLEGMEAPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPEEEIVETLLFEARRLAAEMGELGQPEVSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDN7</accession>
    <name>A0A1Q2CDN7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">L-proline dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_04635</name>
        <name evidence="10" type="ORF">SAMN05428934_101533</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04635"/>
    <dbReference type="EnsemblBacteria" id="AQP44190">
        <property type="protein sequence ID" value="AQP44190"/>
        <property type="gene ID" value="RPIT_04635"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37704">
        <property type="protein sequence ID" value="SDY37704"/>
        <property type="gene ID" value="SAMN05428934_101533"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04635"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003842">
        <property type="term" value="F:1-pyrroline-5-carboxylate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:proline catabolic process to glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025703">
        <property type="entry name" value="Bifunct_PutA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002872">
        <property type="entry name" value="Proline_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01619">
        <property type="entry name" value="Pro_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000197">
        <property type="entry name" value="Bifunct_PutA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pro_dh" evidence="8">
        <location>
            <begin position="120"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="Aldedh" evidence="7">
        <location>
            <begin position="496"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="438"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="766"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="695"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 4">
        <location>
            <position position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000197-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY37704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="1082" mass="116560" checksum="5B872E8F50D69BAB" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDR1</accession>
    <name>A0A1Q2CDR1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Multiple sugar transport system substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05020</name>
        <name evidence="4" type="ORF">SAMN05428934_101610</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY39653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05020"/>
    <dbReference type="EnsemblBacteria" id="AQP44254">
        <property type="protein sequence ID" value="AQP44254"/>
        <property type="gene ID" value="RPIT_05020"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY39653">
        <property type="protein sequence ID" value="SDY39653"/>
        <property type="gene ID" value="SAMN05428934_101610"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05020"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544438" evidence="2">
        <location>
            <begin position="30"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY39653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="434" mass="45962" checksum="E2A143B9180BED65" modified="2017-04-12" version="1">MKRVLKFGAAAIVGALALSACGGDNTADRTTDPTTAGGETTAAGSEAAVDPGSLETTIKILAPSYSDSSEADWQTIIDKFNEEYPNVDVELQIAGWEGFTQTVQGRIQSNDLPDILNDNAFASAAAEGLLYPIDEVLSQETLDAIEPSLLANGVGTDGVQWAAPDIATARLMAYNKDLFEEAGIEAPPTTWAELEEASAKIVALGDDRYGYGMPLGSEEAQVESSLWLWGAGGDWVDGDTLNADTEAAAEAFAQMKKMHAEGYTQSRLEDNRQDVATLFQNGQLGMMMAHSAIVNDAVDKGIDVGLAPIPSKSGEGVALGVTDFIVAFNNEDADRKAATKAFLDLLYSDEMYEAWYKGTGLLPVTSSMIEKGVSEGDEIEAGFLEALPLVKFLPVGYAEWDALQGALQGEAYKVSTDDPATLLAQIQAMADAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDS6</accession>
    <name>A0A1Q2CDS6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2-isopropylmalate synthase</fullName>
            <ecNumber evidence="3">2.3.3.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Alpha-IPM synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Alpha-isopropylmalate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">leuA</name>
        <name evidence="6" type="ORF">RPIT_05035</name>
        <name evidence="7" type="ORF">SAMN05428934_101613</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>3-methyl-2-oxobutanoate + acetyl-CoA + H2O = (2S)-2-isopropylmalate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21524"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.13" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY39735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05035"/>
    <dbReference type="EnsemblBacteria" id="AQP44256">
        <property type="protein sequence ID" value="AQP44256"/>
        <property type="gene ID" value="RPIT_05035"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY39735">
        <property type="protein sequence ID" value="SDY39735"/>
        <property type="gene ID" value="SAMN05428934_101613"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05035"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07942">
        <property type="entry name" value="DRE_TIM_LeuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00572">
        <property type="entry name" value="LeuA_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005668">
        <property type="entry name" value="IPM_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039371">
        <property type="entry name" value="LeuA_N_DRE-TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="SSF110921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00970">
        <property type="entry name" value="leuA_yeast"/>
        <property type="match status" value="1"/>
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            <begin position="46"/>
            <end position="321"/>
        </location>
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        <location>
            <begin position="1"/>
            <end position="24"/>
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            <dbReference type="ARBA" id="ARBA00022679"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00023304"/>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_00572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
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            <dbReference type="PROSITE" id="PS50991"/>
        </source>
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            <dbReference type="EMBL" id="AQP44256.1"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY39735.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="583" mass="64509" checksum="905E5945996FBF32" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
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    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 6">RP1</strain>
        </source>
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            <authorList>
                <person name="Peterson S.W."/>
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            <end position="414"/>
        </location>
    </feature>
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            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="SDY39757.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
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        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="849" mass="93533" checksum="3F88D041734B1F35" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDT4</accession>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="165" mass="18088" checksum="EB7C6DDC3D9EB0B4" modified="2017-04-12" version="1">MSIFKRSAAPSADLTGLTEVLGARADVLAAGSGDRVSLVGTREHLALRRGDQWRVWRWEEVGSGSWNGEAKVFRWRTVTGERFEAALDEVGRLPDLFRERVQASTLVTSVVDAQRGQVQIVGRRGLGSDPTIHWYAVPSGGADLNDPATKQLVVEETDRLAGEYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDY9</accession>
    <name>A0A1Q2CDY9_9ACTN</name>
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        <recommendedName>
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        </recommendedName>
    </protein>
    <gene>
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        <name evidence="10" type="ORF">SAMN05428934_10328</name>
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        <lineage>
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    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
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    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY65791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05405"/>
    <dbReference type="EnsemblBacteria" id="AQP44318">
        <property type="protein sequence ID" value="AQP44318"/>
        <property type="gene ID" value="RPIT_05405"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY65791">
        <property type="protein sequence ID" value="SDY65791"/>
        <property type="gene ID" value="SAMN05428934_10328"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05405"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
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        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
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    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY65791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="362" mass="39471" checksum="5F49FC22E4090CF1" modified="2017-04-12" version="1">MSDEGMFDTDASLARSTRRSLEIEAELGTDPSRFRILTGDRPTGNLHIGHYFGSLENRVRIARMGVETMVLIADYQVITDRDGVGPIRERVYSLLADYLAAGLDENDVTIFAHSAVPALNQLMLPFLSLVTDAELRRNPTVKAETDDTGDRPMSGLMLTYPVHQAADILFCKANLVPVGKDQLPHLEQARVIARRFDERYGRADESQPVFPAPEALLSKSGTVLGLDGTKMSKSKNNTIEIGMSADQTAKLLKRAVTDSNRTITYDPVNRPEVSNLVNLAALCLDRDPVDVAAQIGDGGGGGLKKLVTEAVNEKFAPIRARRAELVADPGHLERVLADGNARANAIADATLDEVRTAMRMSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDZ9</accession>
    <name>A0A1Q2CDZ9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44275">
        <property type="protein sequence ID" value="AQP44275"/>
        <property type="gene ID" value="RPIT_05145"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05145"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="331" mass="35485" checksum="5F1604A4E47EF1A6" modified="2017-04-12" version="1">MTDGRRGYGDWNNNTDTAGHPDGRTAVVPLDVSTMTWGPIFFTGSEANDVIRKGPDGSLYLPTTDPSGKAATGATRTGRSGYVTDQGGAWRFVDDGTGQIHTFDVALNGSDIHTFNSRRVLTSTDGGKSFAESLTTRPENTTDWTRFYWGVAAGGKVYTSAHHTAGLYQQTEVLSRGSWSSIRESRIGSLFPNRTVEFKDNIVSGSTTISSFSGSKLATYVDGFSRSDPATGFTVNVLDFYVDDQSGHLYVLYSDGLIKRTSDVKSFEVIGNAGPGFHSIAVRDSVIYLGGDRGSVWRSDVAVDQLKPGTVTDAAPTKGNGKGKANGKRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE07</accession>
    <name>A0A1Q2CE07_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EamA family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44362">
        <property type="protein sequence ID" value="AQP44362"/>
        <property type="gene ID" value="RPIT_05670"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05670"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="149"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="292" mass="30354" checksum="6CE2F631A4E9D55F" modified="2017-04-12" version="1">MVVVEAYSSAVARVNPVVLVLIAIASVQFGAAVAKGIFTAAHPATLSFLRVTIATTVFLVIARPRWSGRTLRDWLLVLGYGLCLAGMNLAIYLSFARIPIGVAVTLEFVGPLALAVIGSRRLIDLGWVLLAAMGVGLLGALPIGLDPVGVALALLAGAMWAGYIALAGPMGRRWEGLSGLTTGSLLGFVILAVPGLLLAGDSLGRSSVWATMALVALLSTVIPYGLELHARRSIKASTFGILMSIEPAAAAIFAWLVLGEWLGWVEWLAMALVITASVGAVRGAHVTRRPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEC4</accession>
    <name>A0A1Q2CEC4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription antitermination protein NusB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Antitermination factor NusB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nusB</name>
        <name evidence="8" type="ORF">RPIT_06190</name>
        <name evidence="9" type="ORF">SAMN05428934_103183</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the NusB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY69795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06190"/>
    <dbReference type="EnsemblBacteria" id="AQP44453">
        <property type="protein sequence ID" value="AQP44453"/>
        <property type="gene ID" value="RPIT_06190"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY69795">
        <property type="protein sequence ID" value="SDY69795"/>
        <property type="gene ID" value="SAMN05428934_103183"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06190"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00073">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035926">
        <property type="entry name" value="NusB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011605">
        <property type="entry name" value="NusB_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006027">
        <property type="entry name" value="NusB_RsmB_TIM44"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11078">
        <property type="entry name" value="PTHR11078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01029">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48013">
        <property type="entry name" value="SSF48013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01951">
        <property type="entry name" value="nusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="4 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NusB" evidence="7">
        <location>
            <begin position="12"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY69795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="141" mass="15276" checksum="E03DAC1F7EFB33C1" modified="2017-04-12" version="1">MGVAPHYSAQTKARKAALDILFQAELRGDSLAETFAEQRTLAGGTVRELTSRIVLGVAQHQLAIDQRIAESTSQTWPLERMPAVDRNLARIAVYEMDYTDVPAEAVISEAVRLAGDLSTDDSPSFLNGLLSKALAARPTTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CED0</accession>
    <name>A0A1Q2CED0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lar_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06350</name>
        <name evidence="3" type="ORF">SAMN05428934_103215</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06350"/>
    <dbReference type="EnsemblBacteria" id="AQP44479">
        <property type="protein sequence ID" value="AQP44479"/>
        <property type="gene ID" value="RPIT_06350"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70659">
        <property type="protein sequence ID" value="SDY70659"/>
        <property type="gene ID" value="SAMN05428934_103215"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06350"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050043">
        <property type="term" value="F:lactate racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043166">
        <property type="entry name" value="LarA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018657">
        <property type="entry name" value="LarA-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09861">
        <property type="entry name" value="Lar_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lar_N" evidence="1">
        <location>
            <begin position="34"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY70659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="506" mass="54750" checksum="1E2DAEFE742694A8" modified="2017-04-12" version="1">MSRPGFVLEVDDKTPPLLTFSGAQLRFERFGRGTKVLYPADAVHSANPVALIDSALASPIDCEPLAEQLHRDTRLTIVVVDCDRPLPRPQFDVRQTLVERVLETAARAGVDDVEIVIANGLRQRWSAAHVSQVLGDRVATSFLPDGLVNSHDVTADDLVTLGDVDGRPVKFNRRVAESDVVVAVAVRADTGCHCPFIGGLTDADTINSLRGVGATPERQEAVRALVAERVNTFGVTAVLGQPLLAPNLRFVSRREWEWKLGDRLAFATARQVVAALPRQGAQLLHGNPHADYAVVDVVGGSYQAAFDESRLVWQAANAVEVKGQADVLVTSVWGASVDEGDPIGNPLTAAHHALVASAGSHAETPFARQGGALIAFHPLRPRFSNRRQSAAADFYAKVLPETLDPTEIAATHEARASADSWYLDLYRKQFADHPLRVFHQWYEIAEATSHYSEVIWVGGDRRSAALFGHRAATTYADALEIASNQVGRSPEITVLHGPGLALGDVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEJ0</accession>
    <name>A0A1Q2CEJ0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP synthase subunit c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">ATP synthase F(0) sector subunit c</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">F-type ATPase subunit c</fullName>
            <shortName evidence="13">F-ATPase subunit c</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Lipid-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">atpE</name>
        <name evidence="15" type="ORF">RPIT_06690</name>
        <name evidence="16" type="ORF">SAMN05428934_110109</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1T</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1</strain>
        </source>
    </reference>
    <reference evidence="15" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="13">Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the ATPase C chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ10188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_076058514.1">
        <property type="nucleotide sequence ID" value="NZ_FNPU01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06690"/>
    <dbReference type="EnsemblBacteria" id="AQP44539">
        <property type="protein sequence ID" value="AQP44539"/>
        <property type="gene ID" value="RPIT_06690"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ10188">
        <property type="protein sequence ID" value="SDZ10188"/>
        <property type="gene ID" value="SAMN05428934_110109"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06690"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01396">
        <property type="entry name" value="ATP_synth_c_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005953">
        <property type="entry name" value="ATP_synth_csu_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000454">
        <property type="entry name" value="ATP_synth_F0_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020537">
        <property type="entry name" value="ATP_synth_F0_csu_DDCD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038662">
        <property type="entry name" value="ATP_synth_F0_csu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00124">
        <property type="entry name" value="ATPASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="SSF81333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01260">
        <property type="entry name" value="ATP_synt_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00605">
        <property type="entry name" value="ATPASE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 13" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 13" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_C" evidence="14">
        <location>
            <begin position="16"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="site" description="Reversibly protonated during proton transport" evidence="13">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="AQP44539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="SDZ10188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="72" mass="7410" checksum="F4864A9B44594E87" modified="2017-04-12" version="1">MSLLEITGNLNMIGYAIATIAPALGVAWIFASVINGTARQPEARGAMMSTAFIGFAVVEALAIIAIALAFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEJ7</accession>
    <name>A0A1Q2CEJ7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DEDD_Tnp_IS110 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44528">
        <property type="protein sequence ID" value="AQP44528"/>
        <property type="gene ID" value="RPIT_06635"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06635"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="1">
        <location>
            <begin position="20"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="363" mass="39431" checksum="6E74733DAEDF844D" modified="2017-04-12" version="1">MYKTSHTRRHRNPPSGSVVVGIDTHLDIHRAALVDAATGAPVADQQFPATPAGYLELLDWAVGHGRVSRAGVEQTGTYGAGLSAVLHAAGIEVIEINHTERGDRARHGKTDELDAYRAATAAAAGTQKGLAKHYHPAIAALRPLMVLRAHHRSSRQRAWGRVGGMLVTCPDDLADQVRGLNSAQKLARIAAWRPDLTRLHDPVNSYKLALRDLARACLDHDRAIVEIDAQLLRILTPIAPTLLAQHHVGPVTTAQLLITAGHPGRITSGDAFAKLVGVAPLPVQSGKSSRWRLSRSGDRQANSVIHRVVIGRLGTDPRSKTYIQRRVSEGKTRSEAIRALKRHVTRDLWTALQTDLNNLPHTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEL5</accession>
    <name>A0A1Q2CEL5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptide chain release factor 1</fullName>
            <shortName evidence="5">RF-1</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">prfA</name>
        <name evidence="7" type="ORF">RPIT_06725</name>
        <name evidence="8" type="ORF">SAMN05428934_110102</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">Methylated by PrmC. Methylation increases the termination efficiency of RF1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ10059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06725"/>
    <dbReference type="EnsemblBacteria" id="AQP44546">
        <property type="protein sequence ID" value="AQP44546"/>
        <property type="gene ID" value="RPIT_06725"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ10059">
        <property type="protein sequence ID" value="SDZ10059"/>
        <property type="gene ID" value="SAMN05428934_110102"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06725"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00093">
        <property type="entry name" value="Rel_fac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004373">
        <property type="entry name" value="RF-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00019">
        <property type="entry name" value="prfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0488">Methylation</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RF_PROK_I" evidence="6">
        <location>
            <begin position="225"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="5">
        <location>
            <position position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ10059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="355" mass="38634" checksum="2E6876A036AD3EC4" modified="2017-04-12" version="1">MFENAQPLIEEFRDLELQLADPALHGDMARSRRVGRRYAALRPIVEGIDEFRRLSGDREAAAELATVDPSFADEVTELDAALAVATGKLTKLLAPRDPNDDADALVEIKSGEGGDESALFAADLLKMYTKYAEQAGWKVEILDAQETDLGGYKSITVAVKGGAQQEHAPYGRLKFEGGVHRVQRVPVTESQGRIHTSAAGVLVMPDVEADEVEINDDDLRIDVYRASGPGGQGVNTTDSAVRITHLPSGTVVSCQNERSQLQNRESALRMLRARLIQLAEAEAAAAASDARKSQIRTVDRSERIRTYNFPENRITDHRIGYKAHNLDQVLEGSIAPLLDALAEQDLAERLAGVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEM9</accession>
    <name>A0A1Q2CEM9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_06840</name>
        <name evidence="6" type="ORF">SAMN05428934_11078</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06840"/>
    <dbReference type="EnsemblBacteria" id="AQP44563">
        <property type="protein sequence ID" value="AQP44563"/>
        <property type="gene ID" value="RPIT_06840"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09660">
        <property type="protein sequence ID" value="SDZ09660"/>
        <property type="gene ID" value="SAMN05428934_11078"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06840"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDZ09660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="274" mass="29675" checksum="B28411EE6C802877" modified="2017-04-12" version="1">MSYLEVSDLTVRFGSRPPAVNKISFSVGETDRLGIIGQSGSGKSVTALAILGLLPEHASVTGSIRLDGRELVGLPERAMQDLRGDEISMIFQEPMTALDPTMKVGRQVGEVVALHHGERRGSIRDEVLLWLGRVGLSDPERIADSYPHELSGGQRQRALIAMALANRPGLVLCDEPTTALDVLVQRQILALLAEQLADRAALFVSHDLAVVRQVCPRVAVMLRGEIVEEGLIDDIIARPQHPYTQGLIASARLDRVAPGERLPSVADFYPGVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEN7</accession>
    <name>A0A1Q2CEN7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tyrosine phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06865</name>
        <name evidence="3" type="ORF">SAMN05428934_11073</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06865"/>
    <dbReference type="EnsemblBacteria" id="AQP44568">
        <property type="protein sequence ID" value="AQP44568"/>
        <property type="gene ID" value="RPIT_06865"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09567">
        <property type="protein sequence ID" value="SDZ09567"/>
        <property type="gene ID" value="SAMN05428934_11073"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06865"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026893">
        <property type="entry name" value="Tyr/Ser_Pase_IphP-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13350">
        <property type="entry name" value="Y_phosphatase3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="SSF52799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TYR_PHOSPHATASE_2" evidence="1">
        <location>
            <begin position="104"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ09567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="230" mass="25705" checksum="AAE8DAA7BCE01FD2" modified="2017-04-12" version="1">MGINWDGAVNARRVNDTVVRMARREWVSPRGWDAAIADGFTTVVDLRSPYEWQTVRDGDWPMPPDLQRRLRLISAPTEDPEHPRFQELLAPYLDHPAHYPTYLELFGDKVAKALMALAEAPAGVIVHCSAGRDRTGLVVALGQKLAGWPDDEIVAGYIAAAEGINELHRTNPHPRERYLTGVDWRRWIDGRHSALEGFLARLNAPGLLSDAGLSAADLDLIRLRFRMSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEQ3</accession>
    <name>A0A1Q2CEQ3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative glutamate--cysteine ligase 2</fullName>
            <ecNumber evidence="2">6.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Gamma-glutamylcysteine synthetase 2</fullName>
            <shortName evidence="2">GCS 2</shortName>
            <shortName evidence="2">Gamma-GCS 2</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_06940</name>
        <name evidence="4" type="ORF">SAMN05428934_11057</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>ATP + L-cysteine + L-glutamate = ADP + gamma-L-glutamyl-L-cysteine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13285"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.2" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06940"/>
    <dbReference type="EnsemblBacteria" id="AQP44581">
        <property type="protein sequence ID" value="AQP44581"/>
        <property type="gene ID" value="RPIT_06940"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09229">
        <property type="protein sequence ID" value="SDZ09229"/>
        <property type="gene ID" value="SAMN05428934_11057"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06940"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004357">
        <property type="term" value="F:glutamate-cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042398">
        <property type="term" value="P:cellular modified amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01609">
        <property type="entry name" value="Glu_cys_ligase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006336">
        <property type="entry name" value="GCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011793">
        <property type="entry name" value="YbdK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04107">
        <property type="entry name" value="GCS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02050">
        <property type="entry name" value="gshA_cyan_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ09229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="378" mass="42126" checksum="AD5247F5A541CF71" modified="2017-04-12" version="1">MRIKFAQSKQSTIGIEWELAVVDAQTLEQVPAAETLLSTVEDPVDGPIRSEYLTSMIEIVSSVHDTVPKAVAEMTSHLEHCLDVLEPYGLTLLGAGAHPFGDPKRQLPGSKPQYRRVTERNAWWGTQMAINGLHIHTGIDSRDKALPIVYGLARFAPYFIALSASSPYWEGVDTKFASQRTMMFQQLPTNGLPYDMASWDELERYASQLEGVGMIQNPSEIRWDVRPSEWGTVENRIMDSVPTVMEVGAITAFSQCLVERMSRAISSGEPIDRLPQWFMRENKWRAARYGLSADIITPRKDEYLIHVSDGILRWVDELTPIAEELGCAANLGHVRDLVVGGPSYLRQRRVAAAGGDVTDVARSIVEELRAGAPKFKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CET2</accession>
    <name>A0A1Q2CET2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07225"/>
    <dbReference type="EnsemblBacteria" id="AQP44629">
        <property type="protein sequence ID" value="AQP44629"/>
        <property type="gene ID" value="RPIT_07225"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07225"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005361">
        <property type="entry name" value="UPF0158"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03682">
        <property type="entry name" value="UPF0158"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="232" mass="26717" checksum="234C8249784BC851" modified="2017-04-12" version="1">MRGLLYRADAEAIVDVLNSDRQRPQYSLQMTGDLVLVAVDGHGPAVEDAARRIATELRERDWEGDEELALQIEAAYGWVPVPLLRPQPVDLDAFSSVLEGDPALGGGRLELATGEAWPETVFDEAYTGIPYDEEADAPDRWLRVHCLGSRESYRDMERFIDTVDDERLAERLWRAIQGRGAFRRFKDVLYDWPEHQEHQERWYAFNEDRHRGRARAWLVAEGYAPVPPRRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CET4</accession>
    <name>A0A1Q2CET4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Deaminase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Dihydrofolate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07150</name>
        <name evidence="3" type="ORF">SAMN05428934_11014</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07150"/>
    <dbReference type="EnsemblBacteria" id="AQP44618">
        <property type="protein sequence ID" value="AQP44618"/>
        <property type="gene ID" value="RPIT_07150"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08263">
        <property type="protein sequence ID" value="SDZ08263"/>
        <property type="gene ID" value="SAMN05428934_11014"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07150"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="3"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ08263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="176" mass="19476" checksum="21D24BD5EEA18ED0" modified="2017-04-12" version="1">MATLVFGMNQSLDGYVNHDRFAPGPTLFCHFIEEARTQAASIYGRRVYELMSYWDDDDPAWSDDEREFAIAHRRQPKWVASRTLTSVGPNAQLIGGDLGDAVARLKSELDGEIAVAGPRLAGQLTELGLIDEYRIYLHPVVLGGGDPFFAGPRPPLRLISADEMGDDVLRLRYAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEV1</accession>
    <name>A0A1Q2CEV1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07375</name>
        <name evidence="2" type="ORF">SAMN05428934_11432</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000014">
        <property type="protein sequence ID" value="SDZ18392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44652">
        <property type="protein sequence ID" value="AQP44652"/>
        <property type="gene ID" value="RPIT_07375"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ18392">
        <property type="protein sequence ID" value="SDZ18392"/>
        <property type="gene ID" value="SAMN05428934_11432"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07375"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ18392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="135" mass="15078" checksum="F02807FB6BEA270C" modified="2017-04-12" version="1">MTAVDPHDDSLWRWVLQHYRFDPERNQRRWVVVAAYDNEAEFEAALAAHSRQLRDEIDNRDCDGQEQVGGVLWHPGYHAEQARGRLAGEAARHGVDPRPLLQDGPLPSNVAVFGWDADGQAFSLGGDEPPSLPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEV4</accession>
    <name>A0A1Q2CEV4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Copper-translocating P-type ATPase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">Cu+-exporting ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_07305</name>
        <name evidence="10" type="ORF">SAMN05428934_11418</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000014">
        <property type="protein sequence ID" value="SDZ18101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07305"/>
    <dbReference type="EnsemblBacteria" id="AQP44638">
        <property type="protein sequence ID" value="AQP44638"/>
        <property type="gene ID" value="RPIT_07305"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ18101">
        <property type="protein sequence ID" value="SDZ18101"/>
        <property type="gene ID" value="SAMN05428934_11418"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07305"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028096">
        <property type="entry name" value="EfeO_Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011017">
        <property type="entry name" value="TRASH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007029">
        <property type="entry name" value="YHS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13473">
        <property type="entry name" value="Cupredoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04945">
        <property type="entry name" value="YHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00746">
        <property type="entry name" value="TRASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="449"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="765"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="790"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="domain" description="TRASH" evidence="8">
        <location>
            <begin position="868"/>
            <end position="906"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ18101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="930" mass="97521" checksum="2CDE82348F62C570" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEZ1</accession>
    <name>A0A1Q2CEZ1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS1380 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07575"/>
    <dbReference type="EnsemblBacteria" id="AQP44682">
        <property type="protein sequence ID" value="AQP44682"/>
        <property type="gene ID" value="RPIT_07575"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07575"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="1">
        <location>
            <begin position="10"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="469" mass="51308" checksum="FD9D1F18FF41270F" modified="2017-04-12" version="1">MRSTFEVKTTGSYPRVHVDTAKVTAVGQAGGILLTETIRAAGLDQALSEALTRWRKPLAVHDPGKIILDLAMSLVLGGEALSDVATLRAEPGIYGPVASDPTVSRLIATLAEDADKAIKAIAGARQQARARAWALAGQHAPDYETSAEDPVVIDLDASLITAHSEKQQAAATFKRGFGFHPLMAFADHGPEGTGEALVVHLRPGNAGSNTATDHITVTKAALAQLPEKNPRPGRRVLVRADGAGGTKEFTRWLATHRMAYSVGFTLPLDTSTLYQQIPDWVWVPALNADRQAREGADLADFTGLLTLDGWPPGMRVIVRRERPHPGAQLRFDDVDGYRLTAFATNTTTGTLQQLELRHRRRARCEDRIRIAKDTGLVNLPLHGFDQNRIWCQIVALASELQAWSGMLALAGHEARRWEPKRLRYRLYSIPATLARRARRVVLHLAEQSRWAELILDGIGRLRDLPAPAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF29</accession>
    <name>A0A1Q2CF29_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SnoaL-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07655</name>
        <name evidence="3" type="ORF">SAMN05428934_12112</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000021">
        <property type="protein sequence ID" value="SDZ22801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44697">
        <property type="protein sequence ID" value="AQP44697"/>
        <property type="gene ID" value="RPIT_07655"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ22801">
        <property type="protein sequence ID" value="SDZ22801"/>
        <property type="gene ID" value="SAMN05428934_12112"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07655"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="13"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ22801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="112" mass="12031" checksum="E0A1B17AAF6866E2" modified="2017-04-12" version="1">MGLDTATLLAEQVALLEAGDADGLANRYHPQGVVLHEGGAVDGAEAILELFTQAVFPPRRIVKATTVCRTEDTLLYDVLQDVAGNTVRIVGSFVLRDGFIWRHTSLAVPVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF36</accession>
    <name>A0A1Q2CF36_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44718">
        <property type="protein sequence ID" value="AQP44718"/>
        <property type="gene ID" value="RPIT_07785"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07785"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="186" mass="20654" checksum="AB87834050F91C53" modified="2017-04-12" version="1">MQRLARAVVERGYAWYPVEMTSPGWGDRLYGARTHIGEVRIWSHRLSWGVTLGAPGMPVFVDAGVWEACRTGEVLGMARPPIGEQVAWLEELLASRSLPPYEVECLTRLERERREQPPAYTGLPLAIILITSISLIVAMAWASLALDMVGLRVMAAGAFAALLGWLLRPVAAHRAARRARQRREEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF46</accession>
    <name>A0A1Q2CF46_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_07840</name>
        <name evidence="10" type="ORF">SAMN05428934_1138</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07840"/>
    <dbReference type="EnsemblBacteria" id="AQP44728">
        <property type="protein sequence ID" value="AQP44728"/>
        <property type="gene ID" value="RPIT_07840"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16144">
        <property type="protein sequence ID" value="SDZ16144"/>
        <property type="gene ID" value="SAMN05428934_1138"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07840"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="9"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ16144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="317" mass="34016" checksum="71D3BE4D49C707B1" modified="2017-04-12" version="1">MAELFAGRYLLLEPIGEGGMGTVWRVEDLKRNRVVAAKILRQSHSTSLLRFVREQSLRIHHPHVLMPLGWAGEDDRVLFTMPIVAGGSLATLVGDYGALPPLFVAEILRQIASALIAVHDGRLVHRDVKPANILLDATGAGRPHAYLSDFGIAVELDGPRFTETGLVTGTPGYLAPELAALGDPAPASDAYSLGSVGLHLLTGVRPQDVARGAAPNGVPSSLWDTLVALTEPDPQRRMSLPDALARLEAPELAWHDGAAGEVEVFDHFAPEHTDEAERLHQSESDADGADRRLNSRDLVVFGSFGALMIVGILLLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF56</accession>
    <name>A0A1Q2CF56_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF559 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07925</name>
        <name evidence="3" type="ORF">SAMN05428934_11325</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07925"/>
    <dbReference type="EnsemblBacteria" id="AQP44741">
        <property type="protein sequence ID" value="AQP44741"/>
        <property type="gene ID" value="RPIT_07925"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16465">
        <property type="protein sequence ID" value="SDZ16465"/>
        <property type="gene ID" value="SAMN05428934_11325"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07925"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007569">
        <property type="entry name" value="DUF559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04480">
        <property type="entry name" value="DUF559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF559" evidence="1">
        <location>
            <begin position="184"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ16465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="293" mass="32824" checksum="0125BAD5CE43D686" modified="2017-04-12" version="1">MDPFIHEMTRDGVMAARATRWKARALNSYAHRGQLERLLPGVYGKVGAADTLDGKLQAVRAYGDDLVVTRHHAAALTWWPEVECPSTWRLACPRAVEPGYDLVVEQRLIPPPLLTKHQGCWLTAPALTVLDLIPEFDADVVYLALRRRAVTVEQLQKAMALTPRRRGNRRRREILAETASAPWSHLEREAHRHLREAGLTGWRSNHRVDVGQTHYYIDAAFLEEKVGVELDGFEFPSSRDAFERGRARDADLAAVGWLMVHFTAETASDIGKVLPGLLATRRQQLGLPPLGPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF86</accession>
    <name>A0A1Q2CF86_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyl-gamma-glutamyl-phosphate reductase</fullName>
            <shortName evidence="4">AGPR</shortName>
            <ecNumber evidence="4">1.2.1.38</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">N-acetyl-glutamate semialdehyde dehydrogenase</fullName>
            <shortName evidence="4">NAGSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">argC</name>
        <name evidence="7" type="ORF">RPIT_08220</name>
        <name evidence="8" type="ORF">SAMN05428934_11531</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21588"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29123"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.38"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.38" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08220"/>
    <dbReference type="EnsemblBacteria" id="AQP44784">
        <property type="protein sequence ID" value="AQP44784"/>
        <property type="gene ID" value="RPIT_08220"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19640">
        <property type="protein sequence ID" value="SDZ19640"/>
        <property type="gene ID" value="SAMN05428934_11531"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08220"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00108"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003942">
        <property type="term" value="F:N-acetyl-gamma-glutamyl-phosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="entry name" value="AGPR_AS"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="argC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01224">
        <property type="entry name" value="ARGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0028">Amino-acid biosynthesis</keyword>
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    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="6">
        <location>
            <begin position="4"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ19640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="343" mass="35184" checksum="A593233A7CA44CF2" modified="2017-04-12" version="1">MTYTVAVAGCTGYAGGELLRLLLQHPQVQIGALTGNSSVGDRLGDHQPHLHPLANRTVEATTADVLSGHDVVFLALPHGASAAIAAQLDDEVLVVDAGADFRLRDAEEWEKFYGSPHAGTWPYGLPELPGAREALGTARRIAVPGCYPTAATLALLPAVAGDLVDATQIVIVAASGTSGAGKSLKPHLLGAESMGNMSPYGVGGVHRHTPEIVQNLASVTDQSVRVSFTPLLAPMPRGILATCSAPIRDGVDAAAARAAYVEFYEGEPFVDVLREGVWPQTAAVVGSNRVAVQVTVDAAAGRLIAIAAEDNLTKGTAGGAIQSMNLALGLSETLGLSTVGVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFC6</accession>
    <name>A0A1Q2CFC6_9ACTN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_08395</name>
        <name evidence="2" type="ORF">SAMN05428934_1203</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000020">
        <property type="protein sequence ID" value="SDZ22178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44811">
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        <property type="gene ID" value="RPIT_08395"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ22178"/>
        <property type="gene ID" value="SAMN05428934_1203"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ22178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="84" mass="8721" checksum="46173383A385A548" modified="2017-04-12" version="1">MTKLTDELVGHLQALGDTEMPNDVLSSLDALAEIDEKGTGSCYAGLLSARSSANLDITALTKTLEHTSLMLTVTIDAVTNGQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFF1</accession>
    <name>A0A1Q2CFF1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Succinate dehydrogenase flavoprotein subunit</fullName>
        </submittedName>
        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sdhA</name>
        <name evidence="6" type="ORF">RPIT_08575</name>
        <name evidence="7" type="ORF">SAMN05428934_10726</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY96727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08575"/>
    <dbReference type="EnsemblBacteria" id="AQP44838">
        <property type="protein sequence ID" value="AQP44838"/>
        <property type="gene ID" value="RPIT_08575"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY96727">
        <property type="protein sequence ID" value="SDY96727"/>
        <property type="gene ID" value="SAMN05428934_10726"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08575"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033765">
        <property type="term" value="F:steroid dehydrogenase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011280">
        <property type="entry name" value="Succ_DH/Fum_Rdt_flav_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="PTHR11632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632:SF53">
        <property type="entry name" value="PTHR11632:SF53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01811">
        <property type="entry name" value="sdhA_Bsu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="4">
        <location>
            <begin position="56"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="5">
        <location>
            <begin position="536"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY96727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="671" mass="74920" checksum="6B894002A03501A4" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFG4</accession>
    <name>A0A1Q2CFG4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L32</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmF</name>
        <name evidence="7" type="ORF">RPIT_08690</name>
        <name evidence="8" type="ORF">SAMN05428934_10748</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL32 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08690"/>
    <dbReference type="EnsemblBacteria" id="AQP44856">
        <property type="protein sequence ID" value="AQP44856"/>
        <property type="gene ID" value="RPIT_08690"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97238">
        <property type="protein sequence ID" value="SDY97238"/>
        <property type="gene ID" value="SAMN05428934_10748"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08690"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00340">
        <property type="entry name" value="Ribosomal_L32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002677">
        <property type="entry name" value="Ribosomal_L32p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01783">
        <property type="entry name" value="Ribosomal_L32p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01031">
        <property type="entry name" value="rpmF_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544462" description="50S ribosomal protein L32" evidence="6">
        <location>
            <begin position="32"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY97238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="63" mass="7018" checksum="E071CBE25C5BD7BD" modified="2017-04-12" version="1">MAVPKRKMSRSNTRSRRAQWKTTVVPTVVCANPACREPHLQHTACPSCGQYGPRGARRQVVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFQ8</accession>
    <name>A0A1Q2CFQ8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_09220</name>
        <name evidence="2" type="ORF">SAMN05428934_107156</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY99395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09220"/>
    <dbReference type="EnsemblBacteria" id="AQP44943">
        <property type="protein sequence ID" value="AQP44943"/>
        <property type="gene ID" value="RPIT_09220"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY99395">
        <property type="protein sequence ID" value="SDY99395"/>
        <property type="gene ID" value="SAMN05428934_107156"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09220"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY99395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="148" mass="16705" checksum="BC01C637AEB5F5F9" modified="2017-04-12" version="1">MNRFTVRLPAQCPAHEALGRVLDLRVHNQVIPLTTITPARAFCELRPGSSFVARTAVGRFGFDDPMVVEHIGMVPGRAVARLRKEGCAIRGQIRVDCRDTEDGGSTLTWHQDVHLPWWPRSLHWMATPVLRAGYRRVLRQLLARPHGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFY2</accession>
    <name>A0A1Q2CFY2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Ribonuclease H</fullName>
            <shortName evidence="5">RNase H</shortName>
            <ecNumber evidence="4 5">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rnhA</name>
        <name evidence="7" type="ORF">RPIT_09735</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5">Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the RNase H family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="4 5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09735"/>
    <dbReference type="EnsemblBacteria" id="AQP45032">
        <property type="protein sequence ID" value="AQP45032"/>
        <property type="gene ID" value="RPIT_09735"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09735"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09278">
        <property type="entry name" value="RNase_HI_prokaryote_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00042">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022892">
        <property type="entry name" value="RNaseHI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="6">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="7"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="282" mass="30796" checksum="D665D8F3AEC86674" modified="2017-04-12" version="1">MIVAAADGSSLSNPGPAGWAWYISDDAWAAGGWEHGTNNMGELMAVLDLLRSTAHLDEPLRILCDSQYVINSLTKWMPGWKRKGWKKGDGKPVLNVELMKDLDAAMRGRELEFEWVKGHAGHRMNEAADERARAAATAYQQGREPDHGPGFPEAPRPLGRRDFLVGQSDPEPDLFTFADDAADAPRAVEGSAPPRMKARLVTLTRDSVLNPLETPLHPDYVGHAGGAVTDSGVPWRAGGELELLAIDQLAPGVGLARWRLREALHSAVWVELPSGWCLRFAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG35</accession>
    <name>A0A1Q2CG35_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">7,8-dihydro-8-oxoguanine triphosphatase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">8-oxo-dGTP diphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_10010</name>
        <name evidence="4" type="ORF">SAMN05428934_102304</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY57035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10010"/>
    <dbReference type="EnsemblBacteria" id="AQP45082">
        <property type="protein sequence ID" value="AQP45082"/>
        <property type="gene ID" value="RPIT_10010"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57035">
        <property type="protein sequence ID" value="SDY57035"/>
        <property type="gene ID" value="SAMN05428934_102304"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10010"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY57035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="162" mass="18063" checksum="0819A5D5DB5A2970" modified="2017-04-12" version="1">MSFSPELTTLGYILSEDGLRVLLVHRTARQQDEQLGKFNGLGGKVEPGEDIAAAMVREIREEAGIEVTSMRLRGTVSWPGFNGRDVFGFVFLITGFEGAPFARNVEGELAWHDLNTVMELPMWDGDRHFVPLVFDESVPQFHGVIPYDGGHSVETSWRVTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG64</accession>
    <name>A0A1Q2CG64_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Bifunctional protein FolD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="6">Methylenetetrahydrofolate dehydrogenase</fullName>
                <ecNumber evidence="6">1.5.1.5</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="6">Methenyltetrahydrofolate cyclohydrolase</fullName>
                <ecNumber evidence="6">3.5.4.9</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="6" type="primary">folD</name>
        <name evidence="9" type="ORF">RPIT_09840</name>
        <name evidence="10" type="ORF">SAMN05428934_102338</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22812"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,10-methenyltetrahydrofolate + H2O = (6S)-10-formyltetrahydrofolate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="EC" id="3.5.4.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.5" evidence="6"/>
    <dbReference type="EC" id="3.5.4.9" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY58012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09840"/>
    <dbReference type="EnsemblBacteria" id="AQP45050">
        <property type="protein sequence ID" value="AQP45050"/>
        <property type="gene ID" value="RPIT_09840"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY58012">
        <property type="protein sequence ID" value="SDY58012"/>
        <property type="gene ID" value="SAMN05428934_102338"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09840"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3 6" id="KW-0521">NADP</keyword>
    <keyword evidence="1 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THF_DHG_CYH" evidence="7">
        <location>
            <begin position="6"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="THF_DHG_CYH_C" evidence="8">
        <location>
            <begin position="123"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="165"/>
            <end position="167"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY58012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="284" mass="29961" checksum="51723ABFDDACF8B4" modified="2017-04-12" version="1">MTAQRLDGKATAAAIKTELRARVAALRDRGVVPGLATVLVGADPASQNYVRMKHRDCDEVGISSIRVELPADATADQVRAEIEALNSDPACTGYIVQLPVPRHLDENWVLGLIDPDKDADGLHPINLGRLVLGEPATLPCTPRGIVELLRRHDVPISGAEVVVVGRGITVGRPLGLILTRRSENATVTLCHTGTRDLAAHTRRADVVVAAAGVPGMINAEMIREGAALIDVGVSRVEGKTVGDLAADVWDKAGWVTPNPGGVGPMTRAMLLSNVVDRAEQLHAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG68</accession>
    <name>A0A1Q2CG68_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10130</name>
        <name evidence="3" type="ORF">SAMN05428934_102279</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45103">
        <property type="protein sequence ID" value="AQP45103"/>
        <property type="gene ID" value="RPIT_10130"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56386">
        <property type="protein sequence ID" value="SDY56386"/>
        <property type="gene ID" value="SAMN05428934_102279"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10130"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY56386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="128" mass="13790" checksum="44D211F25E6AB630" modified="2017-04-12" version="1">MTEPRPEDVAELPPAPETRVRWFGVVLLAGHLALLVIGAVALWRISGGGWLGAAVAGAFAVIYAFVWRYLLAPGSRTRLGFRERLTTSLILGPVAVVLGALTDIWLPALMATSIVILSDSLNESSRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG77</accession>
    <name>A0A1Q2CG77_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized conserved protein, Alpha-E superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10200</name>
        <name evidence="3" type="ORF">SAMN05428934_102265</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10200"/>
    <dbReference type="EnsemblBacteria" id="AQP45116">
        <property type="protein sequence ID" value="AQP45116"/>
        <property type="gene ID" value="RPIT_10200"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55981">
        <property type="protein sequence ID" value="SDY55981"/>
        <property type="gene ID" value="SAMN05428934_102265"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10200"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007296">
        <property type="entry name" value="DUF403"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04168">
        <property type="entry name" value="Alpha-E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-E" evidence="1">
        <location>
            <begin position="1"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY55981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="306" mass="34170" checksum="D15CC324B6381B11" modified="2017-04-12" version="1">MLSRIAESLFWIGRYLERAEDTGRIVEVHQHQLLDDPTVDHAQAARDLLLLMGRAVEEEEPDVLTYLCYDEKSPVSFVNAFGQAREAARRARETVSTEVWESINTTWLAIRGGRLQRMRPASMFKFVRERCAVISGLADNTMSHDEGWLFLTLGRSIERIDMTSRLLSTPSLARNSPRAWDHVLSGCGAHHAFVQRYGALASERDAAEFLILDRLFPRSLIYTLGSAVDALTQLGPGNQRIRPDDPAARLLGAARASLEFLPPDEILSELPEQMGKLQVVCSQTTQAVSVRYFEGSAAAEWVGGAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG80</accession>
    <name>A0A1Q2CG80_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Succinyl-diaminopimelate desuccinylase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Succinyldiaminopimelate desuccinylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10190</name>
        <name evidence="3" type="ORF">SAMN05428934_102267</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10190"/>
    <dbReference type="EnsemblBacteria" id="AQP45114">
        <property type="protein sequence ID" value="AQP45114"/>
        <property type="gene ID" value="RPIT_10190"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56033">
        <property type="protein sequence ID" value="SDY56033"/>
        <property type="gene ID" value="SAMN05428934_102267"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10190"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009014">
        <property type="term" value="F:succinyl-diaminopimelate desuccinylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010174">
        <property type="entry name" value="Succinyl-DAP_deSuclase_DapE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01900">
        <property type="entry name" value="dapE-gram_pos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="164"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY56033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="356" mass="38336" checksum="CA7711C2481930B7" modified="2017-04-12" version="1">MSDLIALMQQIMDVESVSGNERALADLVEARLGRLPHLTLHRDGDCVVARTTLGRAERVVIAGHLDTVPVAGNLPSRIVEHEDGPRVWGRGACDMKGGVTVMLALAEELAEPNRDITWIFYDHEEVAATLNGLGRLSRNRPDLIEGAFAVLMEPTSAQIEGGCQGTIRIELTTLGVAAHSARAWMGHNAIHDLAPVLETLAGYESEEIEVEGLVFREGLNAVGITGGMASNVIPPSATVQINYRFAPDKTVDDAVARLRDWFPHQDFEVTDASEAARPGLHLPLAQEFVAAIGEPARPKYGWTDVSRFSALGIPAVNYGPGDSSVAHSDDEFCPASDLDKCAAGLRRWLTHQGEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGA1</accession>
    <name>A0A1Q2CGA1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10375"/>
    <dbReference type="EnsemblBacteria" id="AQP45149">
        <property type="protein sequence ID" value="AQP45149"/>
        <property type="gene ID" value="RPIT_10375"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10375"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038330">
        <property type="entry name" value="TspO/MBR-related_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="263" mass="27078" checksum="30DCA53A4982A212" modified="2017-04-12" version="1">MMNKDRLRQIWVTVAEILCVYGTLVGVGVLGSSVESSSDGALSADATLLAPGGTAFSIWSVIYFGLFAYTVWQWLPGNTTSPRARATGWLAGISMLLNAAWILVTQQGWIWVSVGVIAALVITLGIIMRRLTALPPQGWLDRVIVDGTFGAYLGWVSVATCANIAAAGVASGWSLGDGADDWLAVAVLAAAAGVGVMLAYTIGGRFAVAAAMAWGLSWIAIARLFDEPASSIVGIAAIIAVAVVVVVSGLRGADPGRVAVATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGB3</accession>
    <name>A0A1Q2CGB3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ABC transporter substrate-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Peptide/nickel transport system substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_10030</name>
        <name evidence="5" type="ORF">SAMN05428934_102300</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10030"/>
    <dbReference type="EnsemblBacteria" id="AQP45085">
        <property type="protein sequence ID" value="AQP45085"/>
        <property type="gene ID" value="RPIT_10030"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56932">
        <property type="protein sequence ID" value="SDY56932"/>
        <property type="gene ID" value="SAMN05428934_102300"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10030"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544481" evidence="2">
        <location>
            <begin position="27"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="3">
        <location>
            <begin position="140"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY56932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="632" mass="67605" checksum="B606E25FF028500E" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGD2</accession>
    <name>A0A1Q2CGD2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Isoprenyl transferase</fullName>
            <ecNumber evidence="2">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_10535</name>
        <name evidence="4" type="ORF">SAMN05428934_102198</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY54057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10535"/>
    <dbReference type="EnsemblBacteria" id="AQP45179">
        <property type="protein sequence ID" value="AQP45179"/>
        <property type="gene ID" value="RPIT_10535"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY54057">
        <property type="protein sequence ID" value="SDY54057"/>
        <property type="gene ID" value="SAMN05428934_102198"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10535"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="PTHR10291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="SSF64005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="44"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="90"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="221"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY54057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="266" mass="30024" checksum="092654662839D0BE" modified="2017-04-12" version="1">MSWVNRFVDRTWPPKWLYAWYERRELDRLDKSSLPRHVAVLADGNRRWARMNAPGLPLVAGYQAGAAKLMEFVNWCDEAGIQVVTLWVLSTDNLQRAGAEELDPLLQVIQQLVEDLAASRRWRVRAVGALELLPPEIAHSLVASADATRGSSGMQVNVAVAYGGRQELLDAVRSLLSARAADGATLEEVADTLASDEISSHLYTKGQPDPDLIIRTSGEQRLSGFLLWQSAHSEFYFCEALWPDFRRVDFVRALRAYSQRERRFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGF0</accession>
    <name>A0A1Q2CGF0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10660</name>
        <name evidence="2" type="ORF">SAMN05428934_102173</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY53324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10660"/>
    <dbReference type="EnsemblBacteria" id="AQP45199">
        <property type="protein sequence ID" value="AQP45199"/>
        <property type="gene ID" value="RPIT_10660"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY53324">
        <property type="protein sequence ID" value="SDY53324"/>
        <property type="gene ID" value="SAMN05428934_102173"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10660"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY53324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="83" mass="9457" checksum="2D4C23D5264DD415" modified="2017-04-12" version="1">MPPTIDYRPIIPRTLLRCLVAALGMLLCALAPLLPLLIPALADWMSVPPHRYARRSISPAHSYYRDAVDWGEEWLTSRNGFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGF2</accession>
    <name>A0A1Q2CGF2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Flotillin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_10655</name>
        <name evidence="6" type="ORF">SAMN05428934_102174</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family. Flotillin subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY53349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10655"/>
    <dbReference type="EnsemblBacteria" id="AQP45198">
        <property type="protein sequence ID" value="AQP45198"/>
        <property type="gene ID" value="RPIT_10655"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY53349">
        <property type="protein sequence ID" value="SDY53349"/>
        <property type="gene ID" value="SAMN05428934_102174"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10655"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031905">
        <property type="entry name" value="Flotillin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027705">
        <property type="entry name" value="Flotillin_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13806">
        <property type="entry name" value="PTHR13806"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15975">
        <property type="entry name" value="Flot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="4">
        <location>
            <begin position="26"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY53349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="505" mass="53722" checksum="651F7BA8C62D40A1" modified="2017-04-12" version="1">MPFSPVVTAIIGLVVLLLLVGLLIASRYKVAKPNEAFIITGRKGREVRNPETGLVSTDLSGQKVVMGGGVFVIPFIQRLHVLDLSSRRIMVTIRNAVSGQGIKLNVDGVAIVKVGGNEDSIRAAAQRFLSQQEEIETFTQETLAGSLRSIVGSLTVEQIIRDRAAFAQRVTDESESSLTGQGLVLDTFQIQDITDDGTYLSDLGRPESAKLGRMAAVAEAEARREAEQAQIAAEQEIAISKRELVLKQAEIQSETDAARATAAAAGPLAQADRDQAVLLEQEKVAVAQAALKERQLDTEVRRPADAERYRVETAAEAQRNAAIFEAEARKAASIANAEAEAEKARLTGVGEQSRRSALAEAEAIEGAKRGEAEKARRIAEAEAVRAEGEAKAAAVLAVGQAEAEAMDKRAEAFAHYNDAAVLQMLIEILPQMAEKVSAPLGNIDTLTVVSTEGASALPKTVANNMLQTLQMVKDTTGFDLGAVLDKVANKTAGDPTVIKEAPASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGG3</accession>
    <name>A0A1Q2CGG3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_10615</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45193">
        <property type="protein sequence ID" value="AQP45193"/>
        <property type="gene ID" value="RPIT_10615"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10615"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012975839" evidence="2">
        <location>
            <begin position="32"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="327" mass="34754" checksum="158279AE338618E0" modified="2017-04-12" version="1">MMFRWAAGLVCAALVASCAPGPVEPPQPTTASSRPTLSASASPSAEPSLLPDEDLPLAFVVGPALLPAADRVVARLHRAAGHLPVLRVDLTREQATLTALLPDNAVVSYRWRDDEITRVESDIQYFDQATFDPSDYPLDAAERMFDVADLQGVRGELVLQIVEYRAGQVAITITSRPETNTIFFRPDGSAVATLGVTSVADIAAGLQEVIGEATEAYAVGFDATRGYWADLPDDDAGVVLSRSRVGGVPTFETRRLELPTLEVFDPSSIRAAPLAQAIARAQDDADTSCAVQIDRSLGRSGPVAKIDCDGTVTYADLDGRDMTALIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGP9</accession>
    <name>A0A1Q2CGP9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GMP synthase (glutamine-hydrolyzing)</fullName>
            <ecNumber evidence="3">6.3.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_11195</name>
        <name evidence="12" type="ORF">SAMN05428934_10265</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the synthesis of GMP from XMP.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY49980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11195"/>
    <dbReference type="EnsemblBacteria" id="AQP45291">
        <property type="protein sequence ID" value="AQP45291"/>
        <property type="gene ID" value="RPIT_11195"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY49980">
        <property type="protein sequence ID" value="SDY49980"/>
        <property type="gene ID" value="SAMN05428934_10265"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11195"/>
    <dbReference type="UniPathway" id="UPA00189">
        <property type="reaction ID" value="UER00296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003922">
        <property type="term" value="F:GMP synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00884">
        <property type="entry name" value="guaA_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5 9" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="10">
        <location>
            <begin position="13"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="40"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP45291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY49980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="326" mass="35679" checksum="49D1B1D8A493AD36" modified="2017-04-12" version="1">MERALLAERTGAGSIAEYLDAVVQQVRDQVGDRAVLCALSGGVDSSVCAAIVHKAVGDQLTCIFVDHGLMRAGEPELVAELFGRNFGMRLISVDARDRFLGKLAGVDDPEAKRKIIGEEFIRVFEEEAARLGEVDFLVQGTIYPDIIESDSAKGVVKSHHNVGGLPEDMVFDLVEPVKFLYKDEVRELGEAIGLPRELVWRQPFPGPGLGVRVVGAITPEKVRMVRESDQIFRDEIAAAGLDQSIWQYFTVCPGCRSVGVTDGVRTYGEAIVLRAVHSNDAMSADVAELSPDLLRRVTLRICAEVEGVNRVMYDTTPKPPGTIEWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGQ1</accession>
    <name>A0A1Q2CGQ1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipopolysaccharide kinase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Lipopolysaccharide kinase (Kdo/WaaP) family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_11245</name>
        <name evidence="4" type="ORF">SAMN05428934_10254</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY49711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11245"/>
    <dbReference type="EnsemblBacteria" id="AQP45299">
        <property type="protein sequence ID" value="AQP45299"/>
        <property type="gene ID" value="RPIT_11245"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY49711">
        <property type="protein sequence ID" value="SDY49711"/>
        <property type="gene ID" value="SAMN05428934_10254"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11245"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025111">
        <property type="entry name" value="DUF4032"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13224">
        <property type="entry name" value="DUF4032"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DUF4032" evidence="2">
        <location>
            <begin position="227"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="412"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY49711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="459" mass="52287" checksum="EF198811C1F93FBA" modified="2017-04-12" version="1">MPRFLAAKPDSDLIRLPWHLPLAEWPAQHLVALPRGISRHVVRFLTVGDEIFAAKEILEEVAVQEYRMLTELRRLGVPSVDPVGVVLGRVDRDGEPLDPILLTRHLAFSLPYRSLFYPGVKHETVTRLLDAMVALFARLHLTGFYWGDVSLSNILFRRDAGEFAAYLVDAETGELHDQLTDGQRAHDLQIARTNLYGEFLDLEAGGILDASLDPEWLVGTIEDRYQQLWAELTGVEEFDESELYRLEGRVRRLNALGFDVAEIDVDTSPTDRRIRMKPKVVEAGHHTRRLMRLTGLDAEEHQARRLLNDMDTYRAKWAPNAPESVAAHKWLVEVFEPAVNRIPAELRGKRDAAQFFHEVLDYRWYQSQRENREVPTDEAASGYIHEILTNLPDEQMGDLQPVGGELVNKYDPSQGFVEDDDDKPYDPWEDEANDPDVPVMAGFDINALRAKAAAKQKNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGQ8</accession>
    <name>A0A1Q2CGQ8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11175</name>
        <name evidence="3" type="ORF">SAMN05428934_10269</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
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            <strain evidence="3 5">RP1</strain>
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    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
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    </reference>
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    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="RPIT_11175"/>
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        <property type="gene ID" value="SAMN05428934_10269"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="AQP45287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY50092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="86" mass="8805" checksum="E4E41F797BC67EA5" modified="2017-04-12" version="1">MLLASGLSFIGFLLATAAPFLLVVAGALGLRSTPKARLIGRWALGAGLAFTVVQLLTDTLGGSSLLIQLVSLAVAIGFLVVANRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">RP1</strain>
        </source>
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    </dbReference>
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            <end position="32"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="50"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="AQP45328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY48637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="79" mass="8599" checksum="33819514F253523E" modified="2017-04-12" version="1">MGFGDEVKETVGKAKEGLGDAFDNEDLRRDGQQDRIEANVNDMADDVKDAADRKHADAKGGFADAVEDVKDKFDGNPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGT7</accession>
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    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">RP1</strain>
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        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    </dbReference>
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    <dbReference type="InterPro" id="IPR016195">
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    </dbReference>
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            <dbReference type="EMBL" id="AQP45331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="SDY48549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="446" mass="48285" checksum="3B85337CD8AF5320" modified="2017-04-12" version="1">MRTINEPTRTPGERVAALQDYLAGKPQFPDFVTESNNHVHTIYSFSPYTPAMAALKAREAGLMVVGSVDHDSAAAAGELTAAAALLGMGSVTGFECRVYLYSAEEVEQGTAPLHDRKLNNPDTAGIAYMTVQAIPARSRDAVADFLKPIREARLRRTAAMVDRANAILEPLGAELIDLETHIVGRSQFLAGGTITERHLLAAMAGMLIARFGRGESLVDGLREMGLNPSGALADRLADEDNPHLTFDLLGVMKAEFLDQIYVVPDRTECPTMAEVVAFAREIDAIPAYAYLGDVTASPTGDKKAEKFEDDFLEELFGELQRLGMPAVTYMPPRNTPEQMARIAELAREHGMVEVSGVDINTPRQQFNCPELQRSELAHLNEATWALVAHEKLADLDGSLGLFAPDSPVASLALVDRVGRYAELGRALVRDGLTVVEAAERLRGSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
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    <name>A0A1Q2CGW2_9ACTN</name>
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    </protein>
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        <name evidence="2" type="ORF">RPIT_11165</name>
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    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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    </dbReference>
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        <property type="protein sequence ID" value="SDY50149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11165"/>
    <dbReference type="EnsemblBacteria" id="AQP45285">
        <property type="protein sequence ID" value="AQP45285"/>
        <property type="gene ID" value="RPIT_11165"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY50149">
        <property type="protein sequence ID" value="SDY50149"/>
        <property type="gene ID" value="SAMN05428934_10271"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0003677">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY50149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="127" mass="14005" checksum="68FCAC55F909FDDA" modified="2017-04-12" version="1">MPTGKVRFFDADKGFGFISKDDGGDVYVRSNALPDGVTTLKAGQRVEFGVVEGRRGEQALSLTLLEMPPSLSKASRKNPEQMAVIVEDLIKMLDGLGNDYRHRRHPDSKHAGRIAGLLRRVADELEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH66</accession>
    <name>A0A1Q2CH66_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FAD-dependent oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">NADH dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_12130</name>
        <name evidence="5" type="ORF">SAMN05428934_10650</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY91755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12130"/>
    <dbReference type="EnsemblBacteria" id="AQP45459">
        <property type="protein sequence ID" value="AQP45459"/>
        <property type="gene ID" value="RPIT_12130"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY91755">
        <property type="protein sequence ID" value="SDY91755"/>
        <property type="gene ID" value="SAMN05428934_10650"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12130"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006116">
        <property type="term" value="P:NADH oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="PTHR43706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="377"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="4"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY91755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="454" mass="49084" checksum="1C5B7382DF6E1164" modified="2017-04-12" version="1">MTRHRVVIIGSGFGGLFAAKALKHADVDVTLIARTTHHLFQPLLYQVATGMLSEGDIAPATRELLRRHRNTTVLLGLVEDIDLANRVVKWRFHDDEKETPYDSLIVASGAGQSYFGNQHFSTFAPGMKTIDDALELRARIFNAFEVAEFTTDPDERRRLLTFVVVGAGPTGVEMAGQIRELAAGTLNNEFRSIDPAEARVILIDGADQVLPPFGPKLGAATQETLEDLGVEIILGALVTDLDGTSVTYKTKDGELHTIDSVCKVWAAGVQGSELGQVLADQSEATLDRAGRVVVDEDLSLPGHPEVFVVGDLMSVPGVPGVAQGAIQGARHAVKKIRARVEGAPDPGPFRYRDKGSMATISKFAAVAMIGKLRLTGFIAWVAWLFLHLLYIAGFKQRITTLVSWAITFISGGRAQRVVTNQQMVGRLALERLGARSSGKLFRGSTADEQPPGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH84</accession>
    <name>A0A1Q2CH84_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methylated-DNA--protein-cysteine methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.63</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">6-O-methylguanine-DNA methyltransferase</fullName>
            <shortName evidence="7">MGMT</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">O-6-methylguanine-DNA-alkyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_12300</name>
        <name evidence="11" type="ORF">SAMN05428934_10616</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:53428"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:13555"/>
            <dbReference type="Rhea" id="RHEA-COMP:13556"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:137386"/>
            <dbReference type="ChEBI" id="CHEBI:137387"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 7">
            <text>a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = a 2'-deoxyguanosine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:11367"/>
            <dbReference type="Rhea" id="RHEA-COMP:11368"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:85445"/>
            <dbReference type="ChEBI" id="CHEBI:85448"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MGMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.63" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY91008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12300"/>
    <dbReference type="EnsemblBacteria" id="AQP45486">
        <property type="protein sequence ID" value="AQP45486"/>
        <property type="gene ID" value="RPIT_12300"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY91008">
        <property type="protein sequence ID" value="SDY91008"/>
        <property type="gene ID" value="SAMN05428934_10616"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12300"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003908">
        <property type="term" value="F:methylated-DNA-[protein]-cysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA dealkylation involved in DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00772">
        <property type="entry name" value="OGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001497">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008332">
        <property type="entry name" value="MethylG_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023546">
        <property type="entry name" value="MGMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036631">
        <property type="entry name" value="MGMT_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02870">
        <property type="entry name" value="Methyltransf_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="SSF46767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53155">
        <property type="entry name" value="SSF53155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00589">
        <property type="entry name" value="ogt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00374">
        <property type="entry name" value="MGMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 7 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_1N" evidence="9">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_binding_1" evidence="8">
        <location>
            <begin position="75"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; methyl group acceptor" evidence="7">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP45486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY91008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="162" mass="17405" checksum="763A6055EDAA2F9B" modified="2017-04-12" version="1">MRHSILDSPIGPLTLIERDGGLAALYMAEHAHAPGTAARGERVDDALPEATQQLRQYFAGERSEFDIPLNPAGTEFQRQVWAALTEIPYGETRTYGQLAAGLGRPSSARAVGMAVGRNPISIVVPCHRVVGTNGKLTGYAGGMARKEFLLAHERGQALSRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH87</accession>
    <name>A0A1Q2CH87_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Monosaccharide ABC transporter ATP-binding protein, CUT2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_11985</name>
        <name evidence="6" type="ORF">SAMN05428934_10678</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11985"/>
    <dbReference type="EnsemblBacteria" id="AQP45430">
        <property type="protein sequence ID" value="AQP45430"/>
        <property type="gene ID" value="RPIT_11985"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92368">
        <property type="protein sequence ID" value="SDY92368"/>
        <property type="gene ID" value="SAMN05428934_10678"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11985"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
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    </dbReference>
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        <location>
            <begin position="8"/>
            <end position="245"/>
        </location>
    </feature>
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        <location>
            <begin position="266"/>
            <end position="510"/>
        </location>
    </feature>
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        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP45430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY92368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="520" mass="56619" checksum="CE099A315F8137CD" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHB8</accession>
    <name>A0A1Q2CHB8_9ACTN</name>
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        <submittedName>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="4" type="ORF">SAMN05428934_104205</name>
    </gene>
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP45504">
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    </dbReference>
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        <property type="gene ID" value="SAMN05428934_104205"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY80686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="305" mass="32151" checksum="6AFCB91F3A892DD2" modified="2017-04-12" version="1">MPNFRGIVPPVITPMHTDGSVDFESLDRLVDHLIDGGMHGLFILGSSGQVAYLTDSERDEVTARCVKRAAGRVPVLVGTPDFTARRIAETAKRAEDLGADAVVVTAPLYALNDVAEIERHFRIIAEAVSVPVFAYNVPVRVHSYLGLATLMNLAKDGVIAGVKDSSGDDVGFRRLVAANRAAGHPLELLTGHEVMCDGMFLLGADGAVPGLGNVDPAGYARMWDAAQAGDWVAVRDEQDRIARLFEIAFVPQGRSGDAGGIGAFKQALASLGIIASGAMPAPMEPLTSDDVAGIETILREVGLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHC3</accession>
    <name>A0A1Q2CHC3_9ACTN</name>
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        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_12450</name>
        <name evidence="11" type="ORF">SAMN05428934_104195</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY80412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12450"/>
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        <property type="protein sequence ID" value="AQP45512"/>
        <property type="gene ID" value="RPIT_12450"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY80412"/>
        <property type="gene ID" value="SAMN05428934_104195"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12450"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
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        <property type="entry name" value="HATPase_C"/>
    </dbReference>
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        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
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        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
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        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HATPase_c"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
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        <location>
            <begin position="22"/>
            <end position="368"/>
        </location>
    </feature>
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        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="84"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="144"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP45512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY80412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="368" mass="38987" checksum="675AFEE8D9A0E851" modified="2017-04-12" version="1">MRSLRARLTASHVAVVLVAAAITLLLTRAITPALYDRLDRGPHRGPPTALGFRQQMLDAVDLALLIGAGVGVLTATILGSVVAWRFAGRIRSLQQAAREIAAGGYDTPVPRPPERELAALAADLDGLGASLGDTEARRVRLLGDVAHELRTPLTVVGGYVEGMIDGVVPTTPEQLALISREVERMRRLSDDLTALSKAQEPAGLELRRSRIDVSHVVEEAARRLAPQAADAGVTLSVEASEAWAEVDGERVAQIVTNLVGNALRAVNDGGRVEVLSRPVGDRVEVTVSDDGEGLAADDLERVFERFYRVHRRSGDERGGGSGIGLTIARQIARAHGGDLVARSPGPGLGATFTLLLPALAERGVRLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHF8</accession>
    <name>A0A1Q2CHF8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cell division protein</fullName>
        </submittedName>
        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_12700</name>
        <name evidence="8" type="ORF">SAMN05428934_104147</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY79073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12700"/>
    <dbReference type="EnsemblBacteria" id="AQP45558">
        <property type="protein sequence ID" value="AQP45558"/>
        <property type="gene ID" value="RPIT_12700"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY79073">
        <property type="protein sequence ID" value="SDY79073"/>
        <property type="gene ID" value="SAMN05428934_104147"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12700"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001182">
        <property type="entry name" value="FtsW/RodA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474">
        <property type="entry name" value="PTHR30474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01098">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY79073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="464" mass="50217" checksum="642B9FF150DE390D" modified="2017-04-12" version="1">MSAAVQPAVSAEVIVFRQRRNVELVLIAFAQLFGFVGWVLTHLNLYDVLPENLTTVAAIWFGLGLAAHLVVRFRLPYADPVILPSVFLLNGLGLAMIYRIDQIPEPPRTDASTQLLWTALGLGLFSAVVIVLRDHRRLQRYPYLLFIGGLTLLLLPLIPGLGVTSGGAQIWIRLFGFSFQPAEVAKILLAVAFAAYLYEHREVLALAGRRVLGIELPRARDLGPILVMWLASLAVMVFQNDLGTSLLFFGLFTVMIYIATERPAWPILASILFVGAALAANAFTNHVPRRVNAWLDPFSNYDANLQIISAQFGYAWGGLFGRGWGLGRPGLTPLAKSDMIAAAVGEELGILGLMAVILVYALLVARGFKTALISPDGFGKLLAAGLSFSFALQVFSIIGGVTRLLPLTGLTTPFMSQGGSSLIANWMIIGILLVISHRARVPQAATAAPQSPQQIDDLTVVIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHG1</accession>
    <name>A0A1Q2CHG1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Glucose-1-phosphate thymidylyltransferase</fullName>
            <ecNumber evidence="4 6">2.7.7.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_12640</name>
        <name evidence="9" type="ORF">SAMN05428934_104158</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>alpha-D-glucose 1-phosphate + dTTP + H(+) = diphosphate + dTDP-alpha-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:15225"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37568"/>
            <dbReference type="ChEBI" id="CHEBI:57477"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.7.7.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the glucose-1-phosphate thymidylyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.24" evidence="4 6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY79407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12640"/>
    <dbReference type="EnsemblBacteria" id="AQP45547">
        <property type="protein sequence ID" value="AQP45547"/>
        <property type="gene ID" value="RPIT_12640"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY79407">
        <property type="protein sequence ID" value="SDY79407"/>
        <property type="gene ID" value="SAMN05428934_104158"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12640"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008879">
        <property type="term" value="F:glucose-1-phosphate thymidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045226">
        <property type="term" value="P:extracellular polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02538">
        <property type="entry name" value="G1P_TT_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005907">
        <property type="entry name" value="G1P_thy_trans_s"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43532">
        <property type="entry name" value="PTHR43532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01207">
        <property type="entry name" value="rmlA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="7">
        <location>
            <begin position="3"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY79407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="289" mass="31616" checksum="C6F08E6EE06F2990" modified="2017-04-12" version="1">MRGIILAGGTGSRLHPITLGTSKQLMPVYDKPMIYYPLATLIFAGIRDILIITTPHEAQAFHNLLGTGEQFGVDFTFAVQPEPKGLAQAFTIGADFVEGEKSCLILGDNIFSGPGLGTRLQQRAADVDGALVFGYQVADPTAYGVVEVDSAGRAISIEEKPAEPKSHWAVPGLYFYDEQVAGIAADLKPSSRGELEITDVNRVYMEQGRLHVDLLPRGTAWLDTGTFDSLNDASNFVRTLQSRQGLQVGCPEEAAWRRGFLTDDELVERAQRYEKSGYGTYLRNLLTWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHH2</accession>
    <name>A0A1Q2CHH2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Gluconokinase</fullName>
            <ecNumber evidence="4 9">2.7.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_12510</name>
        <name evidence="11" type="ORF">SAMN05428934_104184</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + D-gluconate = 6-phospho-D-gluconate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19433"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18391"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate acid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the gluconokinase GntK/GntV family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.12" evidence="4 9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY80129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12510"/>
    <dbReference type="EnsemblBacteria" id="AQP45523">
        <property type="protein sequence ID" value="AQP45523"/>
        <property type="gene ID" value="RPIT_12510"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY80129">
        <property type="protein sequence ID" value="SDY80129"/>
        <property type="gene ID" value="SAMN05428934_104184"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12510"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046316">
        <property type="term" value="F:gluconokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02021">
        <property type="entry name" value="GntK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006001">
        <property type="entry name" value="Therm_gnt_kin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43442">
        <property type="entry name" value="PTHR43442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01313">
        <property type="entry name" value="therm_gnt_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP45523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY80129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="183" mass="20313" checksum="4F729EB5B192B001" modified="2017-04-12" version="1">MDVHSDPARQSPVHLIVMGVTGTGKSTVGEGLAEHFGLVFAEGDLFHSQANIDKMAAGHPLTDEDRWPWLRSIRDWMTDKAAEGRSTVVACSALREVYRDVLREADGVVFFVHVVLPEEVNHSRLENRSGHYMKSDMLESQLDTLEHLDDDESGILVLNVGNPDDVVADAVRAVEDRFHIDSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHK7</accession>
    <name>A0A1Q2CHK7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12900</name>
        <name evidence="3" type="ORF">SAMN05428934_104107</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12900"/>
    <dbReference type="EnsemblBacteria" id="AQP45594">
        <property type="protein sequence ID" value="AQP45594"/>
        <property type="gene ID" value="RPIT_12900"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY77960">
        <property type="protein sequence ID" value="SDY77960"/>
        <property type="gene ID" value="SAMN05428934_104107"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12900"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY77960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="402" mass="42027" checksum="9AFE0F2971517B45" modified="2017-04-12" version="1">MANTEVEVGVARQGSLRANNLSLAARFIYRSATPVARVDVANATGMTRSTASRLVDDLVSGGIVSESAPTLTNRRGRPAVPLRPAAGTLVALGLEINVTHMAARLVDLTGDVIDAADEMGDFIGADPAELSARLARMGRQVLDARPEGTRLAAIRVALPGLVDSTTNVLLRAPNLSWHNIAAGELLREAGLTEVGEVDFGVANEADCAAFYVGHDAPGRPSAFNDFLYLSGETGIGSALLRSGRVALGTRGWAGEIGHVCISPDGPLCRCGARGCLERYAGTGALIERAGVDDISDFQALVAAGDHDALISLDEAGRALGIALSNALNLLDETTIVLGGDLALFIDHYRPLIERELETRHLARAFVDVQLSAATPDHAAPALGAAYSGLDRVLAEPSRWCDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHL9</accession>
    <name>A0A1Q2CHL9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Replicative DNA helicase</fullName>
            <ecNumber evidence="3 12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">RPIT_12965</name>
        <name evidence="15" type="ORF">SAMN05428934_10494</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1T</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1</strain>
        </source>
    </reference>
    <reference evidence="14" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the helicase family. DnaB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3 12"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12965"/>
    <dbReference type="EnsemblBacteria" id="AQP45604">
        <property type="protein sequence ID" value="AQP45604"/>
        <property type="gene ID" value="RPIT_12965"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY77609">
        <property type="protein sequence ID" value="SDY77609"/>
        <property type="gene ID" value="SAMN05428934_10494"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12965"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00984">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036185">
        <property type="entry name" value="DNA_heli_DnaB-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007692">
        <property type="entry name" value="DNA_helicase_DnaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007693">
        <property type="entry name" value="DNA_helicase_DnaB-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016136">
        <property type="entry name" value="DNA_helicase_N/primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00772">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48024">
        <property type="entry name" value="SSF48024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00665">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="11 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 12 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 12" id="KW-0639">Primosome</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="13">
        <location>
            <begin position="185"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="AQP45604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="SDY77609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="450" mass="49877" checksum="232EFECEA1BF30FA" modified="2017-04-12" version="1">MTQAAVYDDRDLDRTPPQDLAAEQSVLGAMMMSKDAISDVVEVLRGVDFYRPNHETIFDAIINLYGRGEPADPITVAGELGKSGQLGKVGGAVYLHDLLSSVSIAANAIYYAELVRDKAILRRLVNASIRIAQLGYSGQGEVDKIVDEAQQTLFEVTDRNAAEDYKSLRELIEPTFDEMEAIASSGDALSGVPTGFTELDRITNGLHPGQMVIVAARPGVGKSTFALDVCRSAAIHHNLTTAFFSLEMSRTEIVMKILSAEASVPLGRIRGGKMDESDWQRVTDKSAILGEKNFFIDDSPNLTMMEIRAKARRLKQRHDLQLLAIDYIQLMSSGKKVESRQLEVSEFSRQIKLLAKELEIPVIALSQLSRNTEQRKDGIPQLSDLRESGSLEQDADIVLMLHRPEMYTQNPTDEERGLATFHIPKHRNGETGRIDALFQGHYSRFTNAPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHR4</accession>
    <name>A0A1Q2CHR4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ligand-binding protein SH3</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Quaternary ammonium compound-resistance protein SugE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_13230</name>
        <name evidence="8" type="ORF">SAMN05428934_10441</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY76131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13230"/>
    <dbReference type="EnsemblBacteria" id="AQP45652">
        <property type="protein sequence ID" value="AQP45652"/>
        <property type="gene ID" value="RPIT_13230"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY76131">
        <property type="protein sequence ID" value="SDY76131"/>
        <property type="gene ID" value="SAMN05428934_10441"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13230"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000390">
        <property type="entry name" value="Small_drug/metabolite_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045324">
        <property type="entry name" value="Small_multidrug_res"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30561">
        <property type="entry name" value="PTHR30561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00893">
        <property type="entry name" value="Multi_Drug_Res"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="4 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544502" evidence="6">
        <location>
            <begin position="24"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY76131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="124" mass="12800" checksum="06E49A3A6914BD0B" modified="2017-04-12" version="1">MTSRFAWPLLLVSAVLEAVWANALSASDGFANVVPTVVFLVATVLSVVGLGLAMKHIPTGTAYAVWTSVGTVLTVAYSVAIGAEEISWLKALFLAGIVACVVGLKRLDASTPAGADVTGRRRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHS7</accession>
    <name>A0A1Q2CHS7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipid kinase, YegS/Rv2252/BmrU family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13050</name>
        <name evidence="3" type="ORF">SAMN05428934_10477</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13050"/>
    <dbReference type="EnsemblBacteria" id="AQP45620">
        <property type="protein sequence ID" value="AQP45620"/>
        <property type="gene ID" value="RPIT_13050"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY77138">
        <property type="protein sequence ID" value="SDY77138"/>
        <property type="gene ID" value="SAMN05428934_10477"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13050"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045540">
        <property type="entry name" value="YegS/DAGK_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19279">
        <property type="entry name" value="YegS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="1">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY77138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="323" mass="35313" checksum="7F1105AC76C8D3CA" modified="2017-04-12" version="1">MPRAAVIFNPTKIDRADLAAVVDKAQQNAGWEESLWLETEADDPGTGMARRAVEEGVDVVLGVGGDGTIRAVSEGLRGASVPLALCPQGTGNLLARNLKLTLDNLEESVDAAFNGVSRPVDLAVADFTRPDGSSEERTFVVMAGVGLDAQIMSTTDEKLKKKVGMLAYVKAGIEALRENRRMRIQFKLDDDQPQRARIHTVLIGNCGSIGANVMLLPDAAVDDGLLDVVAVRPQGVWGWPKLAWKVLVDNALFRRFKSDADRRKSDDTRDLNYQQVRQIEIRFASPEEIELDGDHMGEISRVRVSVEHGGLNVMMPEGWEPSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHT1</accession>
    <name>A0A1Q2CHT1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glucose-1-phosphate adenylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_13025</name>
        <name evidence="5" type="ORF">SAMN05428934_10482</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13025"/>
    <dbReference type="EnsemblBacteria" id="AQP45615">
        <property type="protein sequence ID" value="AQP45615"/>
        <property type="gene ID" value="RPIT_13025"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY77277">
        <property type="protein sequence ID" value="SDY77277"/>
        <property type="gene ID" value="SAMN05428934_10482"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13025"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008878">
        <property type="term" value="F:glucose-1-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011831">
        <property type="entry name" value="ADP-Glc_PPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43523">
        <property type="entry name" value="PTHR43523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="3">
        <location>
            <begin position="8"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY77277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="389" mass="42099" checksum="0ACE33F53C182B64" modified="2017-04-12" version="1">MHIPRTYALILAGGEGSRLEGLTDAKPKPVLPVGGTFRLIDISLSNLAQSHLSDIGIVEQYLPHSLNTYLSAGRPWDLDRNHGGLEVLAPFEGGPGEGFAKGNADSIYRQREVIRAFDPEYVLVLSADHLYTMNFLDVLSTHIEKEADLTIVTTLVDEDPSRYGVVQVDDAGTVTRFDYKPDDPEGRLVATEVFVYTASQLLAALEELTADGGELEDYGDQLIPWFVEHRKVVEHRHDDYWLDLGTLQSYWTANLQILDGNGVVLDDPRWRIYSALPQLPPARVMGGAEVHDSLLSSGSVVEGEVRHSVIGSAAIIEAGATVVDSVVLDGARIGPGVSLVNCIVDEGAQVTGGSQRGTGDTVTLIGDDGLIDTRQPLDPEAALPRGFPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHY5</accession>
    <name>A0A1Q2CHY5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha-L-arabinofuranosidase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Alpha-N-arabinofuranosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_13405</name>
        <name evidence="5" type="ORF">SAMN05428934_1047</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 51 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY75164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13405"/>
    <dbReference type="EnsemblBacteria" id="AQP45683">
        <property type="protein sequence ID" value="AQP45683"/>
        <property type="gene ID" value="RPIT_13405"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY75164">
        <property type="protein sequence ID" value="SDY75164"/>
        <property type="gene ID" value="SAMN05428934_1047"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13405"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046373">
        <property type="term" value="P:L-arabinose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010720">
        <property type="entry name" value="Alpha-L-AF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06964">
        <property type="entry name" value="Alpha-L-AF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00813">
        <property type="entry name" value="Alpha-L-AF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-L-AF_C" evidence="3">
        <location>
            <begin position="290"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY75164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="498" mass="55026" checksum="D9D117F5BFB36297" modified="2017-04-12" version="1">MEATLRIDPAFTVGPVRRRTFGSFVEHLGRCVYTGIYEPGHPTADEQGFRGDVLDLVREMGVSTVRYPGGNFVSGYRWEDGIGPVESRPKRLDLAWHSLEPNEVGTDEFMAWAKKAGVEPMMAINLGTRGVLEALDIVEYCNVPAGSDWAERRRTNGADDPYRVKMWCLGNEMDGPWQMGHKTPAEYGRIATEAARAMRMIDPDLELVACGSSGRGMETFGEWERVVLTEAYDQIDMISAHAYYWEKDSGLQEFLVSAEDMDRFIDQVGATIDAVAAARKTDKKIGISFDEWNVWYIDRDPSKPPTGDDWPIAPRLLEDNYSVADAVVVGNLLISLLRHTDRVWSASQAQLVNVIAPIMAEPGGPVWKQTTFHPFALTSANARGDVVRVLVDGPTIETGQFGDVQALDAVATWADDGAAVFVVNRHATEAMQTEIELPAGCSLVQALTLHHEDHTWKASADDDSSVGVEPNETARLDDRILSVTLPPISWTMITLATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHY9</accession>
    <name>A0A1Q2CHY9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase_M23 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13755</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45738">
        <property type="protein sequence ID" value="AQP45738"/>
        <property type="gene ID" value="RPIT_13755"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13755"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000841">
        <property type="entry name" value="Pept_M23A_Blytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00933">
        <property type="entry name" value="BLYTICPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013383675" description="Peptidase_M23 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="52"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="363" mass="39148" checksum="A53081D66520EFA9" modified="2017-04-12" version="1">MVTLLLTALGVVVAPPARAAELPGFPMALPIGWGEVVQAGGTHPHATSVRSSVDLGASGGRSIDVVAAADGIVTVSGAGSWSRCQVVIQHDDGWQTRYYHLKSIPSGLQSGQLVKAGTKLGMTAMPGSETCGRGNFRHVHFTLQRNGVEMPIDGLSLGGYTVRSSGSSYCGYWTRNSDGAIVADARRSCYAVPSVSNTLLHPADLDRDASISRGDERPAISATDTIDPALVYTTEGVHSVGGRAWRTACEPYSQTERCRTEIWANTVVQRYGTNVLQEGWAFNNLTYVESPRSLWADNPLGNNDEWTSDDGRKWRTECDTPATGRNGCRSYTYATIVSATTTSRGTTFERVTDWTFNNIVRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI13</accession>
    <name>A0A1Q2CI13_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D-2-hydroxyacid dehydrogenase (NADP+)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13920</name>
        <name evidence="3" type="ORF">SAMN05428934_11116</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ11868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13920"/>
    <dbReference type="EnsemblBacteria" id="AQP45766">
        <property type="protein sequence ID" value="AQP45766"/>
        <property type="gene ID" value="RPIT_13920"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ11868">
        <property type="protein sequence ID" value="SDZ11868"/>
        <property type="gene ID" value="SAMN05428934_11116"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13920"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh_C" evidence="1">
        <location>
            <begin position="59"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ11868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="259" mass="28452" checksum="323174FF98FD6A2B" modified="2017-04-12" version="1">MCNGLFLHHHHSDFPQLRFVHLTSAGLDRAPVRELEERGVDLRSATGVYSIPVAEWVVTQVLQLYKRSRDFWRHQQEHRWVKNRDLPELAGSTVTIVGFGDIGREVAKRLRGFDVRIVAVNSEDRPSSLADMTFGAADLGAALRIADVVILALPLTPGTRHLIDAAALQLMKPDAVLVDVSRGGIVDQEALLAALDEGRFRGVALDVFEMFALSPLPWQASVAAGPANLAATCYWPCCCSPSSSATSSSRWEWARTGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI24</accession>
    <name>A0A1Q2CI24_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Beta sliding clamp</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">RPIT_13635</name>
        <name evidence="14" type="ORF">SAMN05428934_11172</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a ring-shaped head-to-tail homodimer around DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the beta sliding clamp family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13635"/>
    <dbReference type="EnsemblBacteria" id="AQP45723">
        <property type="protein sequence ID" value="AQP45723"/>
        <property type="gene ID" value="RPIT_13635"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12909">
        <property type="protein sequence ID" value="SDZ12909"/>
        <property type="gene ID" value="SAMN05428934_11172"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13635"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00140">
        <property type="entry name" value="beta_clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001001">
        <property type="entry name" value="DNA_polIII_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022635">
        <property type="entry name" value="DNA_polIII_beta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022637">
        <property type="entry name" value="DNA_polIII_beta_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022634">
        <property type="entry name" value="DNA_polIII_beta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30478">
        <property type="entry name" value="PTHR30478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00712">
        <property type="entry name" value="DNA_pol3_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02767">
        <property type="entry name" value="DNA_pol3_beta_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02768">
        <property type="entry name" value="DNA_pol3_beta_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000804">
        <property type="entry name" value="DNA_pol_III_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00480">
        <property type="entry name" value="POL3Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00663">
        <property type="entry name" value="dnan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 9" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol3_beta" evidence="10">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_2" evidence="11">
        <location>
            <begin position="127"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_3" evidence="12">
        <location>
            <begin position="260"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP45723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDZ12909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="386" mass="41185" checksum="4DECDA6A5A8C69A9" modified="2017-04-12" version="1">MKIRVEKDALADAVAWVARSLPNRPTAPILAGMLLEADANGVTLSSFDSTTSAKVKLPATVTDEGTVLVSGRLLAEIARSLPNKPVDLAADHSKVELTCGQARFTLQTLPVDEYPTLPDMPTQTGTVDAAMFEKAVGQVFVAAGRDELLNVFTGIKMEIDGENLSLLATDRYRMALKELTWRPSSPSVEGAVLVPGKVLSDTAKSMTSGETVTVSLSTTEAEGEGLAGFVGESARGSREATTRLLSQAFPKVRHLMDVDATVSVRVNTGDLLAAVKRVSLVAERNTPLRMRINDDHIALEAATGDQAQASEAIEAEVEISGDEQSITDAGFNPHYLLDALTALDAPFAHFSFTQPGKPCLIMGLASIDGDPLTDYRHVIMLMRLPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI92</accession>
    <name>A0A1Q2CI92_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">N-acylglucosamine 2-epimerase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Sulfoquinovose isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_14390</name>
        <name evidence="2" type="ORF">SAMN05428934_11260</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ15317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14390"/>
    <dbReference type="EnsemblBacteria" id="AQP45848">
        <property type="protein sequence ID" value="AQP45848"/>
        <property type="gene ID" value="RPIT_14390"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ15317">
        <property type="protein sequence ID" value="SDZ15317"/>
        <property type="gene ID" value="SAMN05428934_11260"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14390"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ15317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="411" mass="46469" checksum="21CC4A83E6325EF8" modified="2017-04-12" version="1">MELFGQDDNPFEDCTHLRWLESHRDDLLDFYQPEVCLDSGGYAYLDAEGHALPEQGAQLWLGARMLHCFSIAHALGRPGAADVVRHGLSFYSDGEGRDHVHGGWFATVGGAAPSDRKELYGQAHLLLGASSAVIAGFPEARKLVDEALRVIDEHYWREAEGRCVEAFDRTFTELDPYRGQNANMHLTEALLTAYEATGDEMLLNRAARIARHIAGRAADPTRGAWRLPEHFDGQWRDLLDYNRDEPRHPFRPYGSQPGHWLEWTKLLLQLRGKGIDEPWLVPAARNLFVGALRDAWAPEGGFAYTVDWDGNVVVAEKFFWEVAEGIGAARYLYDLDPMPTYADAYRGFWRYVALHIVDHERGSWFPELDDENRPVQHTWAGKPDLYHAFQATLYAAVPADEGLAAWAARPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CID7</accession>
    <name>A0A1Q2CID7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type II secretion system protein F (GspF)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14240</name>
        <name evidence="3" type="ORF">SAMN05428934_11230</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ14762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14240"/>
    <dbReference type="EnsemblBacteria" id="AQP45820">
        <property type="protein sequence ID" value="AQP45820"/>
        <property type="gene ID" value="RPIT_14240"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ14762">
        <property type="protein sequence ID" value="SDZ14762"/>
        <property type="gene ID" value="SAMN05428934_11230"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14240"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ14762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="289" mass="31026" checksum="793F3CFBDDAB30C7" modified="2017-04-12" version="1">MIGLVVACGMVVGLGSVLVVRGALTAPVRLSDALAALDRRSVVIEAPPAGLEGFGERAQRRLKLPLSAAQQRLLFMQGRSVGDFFIEKLVWTVAGALLPLFWSMGQLILGNPPGLLPLGLGLALAGAGYFVADIRLRAGAEQERRAATDGIHTFFDLVVLERLANSSAAQATANAAAISDAPLFRRITAGLERARMEQTQPWDELHRIADEWNVPELADFADVMRLEEQGAALAEVLQARVKELRDAHLAHQRTAAQEATEGMALWMTLPALILGITFVTPALLTLVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIF2</accession>
    <name>A0A1Q2CIF2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14615</name>
        <name evidence="3" type="ORF">SAMN05428934_10992</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_064846211.1">
        <property type="nucleotide sequence ID" value="NZ_CP019605.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45887">
        <property type="protein sequence ID" value="AQP45887"/>
        <property type="gene ID" value="RPIT_14615"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06352">
        <property type="protein sequence ID" value="SDZ06352"/>
        <property type="gene ID" value="SAMN05428934_10992"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14615"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ06352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="61" mass="6523" checksum="E16014E0BB90A67B" modified="2017-04-12" version="1">MSALQIIYYVGIVVGIAMFVASWLIRRKQITEGPLARAEKPLMLGGAAVTLAFALLGFATI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIN7</accession>
    <name>A0A1Q2CIN7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplW</name>
        <name evidence="6" type="ORF">RPIT_03050</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03050"/>
    <dbReference type="EnsemblBacteria" id="AQP45989">
        <property type="protein sequence ID" value="AQP45989"/>
        <property type="gene ID" value="RPIT_03050"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03050"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_B">
        <property type="entry name" value="Ribosomal_L23_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_L25/23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="PTHR11620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="97" mass="10777" checksum="D4BDB29945637DCA" modified="2017-04-12" version="1">MRDHRDVILRPVVSEKSYNLLDDGKYTFVVAPDANKTEIKIAIEAIFDVKVTSVNTLNRQGKRRRTRYGSGKKADTKRAIITVAEGQSIDIFGGPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIS6</accession>
    <name>A0A1Q2CIS6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH gntR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_01220</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01220"/>
    <dbReference type="EnsemblBacteria" id="AQP45950">
        <property type="protein sequence ID" value="AQP45950"/>
        <property type="gene ID" value="RPIT_01220"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01220"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="3">
        <location>
            <begin position="16"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="82"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="470" mass="49415" checksum="B634A82B0AE0FF4D" modified="2017-04-12" version="1">MESFRSFSADRAPGSAPLPVQIAAEVRRLITTGALRPGDAIPSSRAVAGDLGVSRGSVTAAYDQLTAEGYLVARPRSATRISSDLTLLTQPPRPGPPPSSPRTTLPTISFLPGHEPTGPLADDPTWRASWRDAVRRTPTLDPLGEPALRQAIAQHLRLSRAMVVDPGSIAVTSGARAGLGLLLNVVGSSVPADPRSRLPRVAVESPGFPGLRRLLTQVGVDVVPVPVGADGFHRASLNDAHSARPVDLVLVTPNHQYPLGGALPARARQELIAWARANASLLVEDDYDAEYRHLGPPLPPLWQLDPDVVAHLGTFSSVLSPAVATGYLVVPERLRPAVVAAKAALGATVSPLAQLALARYLDEGGLRKRLGRARRRLAAARAEAAALLPELGEHGQVQDTGHLLVIETPPLVAARWREAAAAKGLLVGDLADGWAGGSPRAGIVVDYGGHEPARVRRALRLLATAAPRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIW4</accession>
    <name>A0A1Q2CIW4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Apolipoprotein N-acyltransferase</fullName>
            <shortName evidence="8">ALP N-acyltransferase</shortName>
            <ecNumber evidence="8">2.3.1.269</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">lnt</name>
        <name evidence="10" type="ORF">RPIT_05990</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a glycerophospholipid + N-terminal S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein] = a 2-acyl-sn-glycero-3-phospholipid + H(+) + N-acyl-S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein]</text>
            <dbReference type="Rhea" id="RHEA:48228"/>
            <dbReference type="Rhea" id="RHEA-COMP:14681"/>
            <dbReference type="Rhea" id="RHEA-COMP:14684"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136912"/>
            <dbReference type="ChEBI" id="CHEBI:140656"/>
            <dbReference type="ChEBI" id="CHEBI:140657"/>
            <dbReference type="ChEBI" id="CHEBI:140660"/>
            <dbReference type="EC" id="2.3.1.269"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Protein modification; lipoprotein biosynthesis (N-acyl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.269" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05990"/>
    <dbReference type="EnsemblBacteria" id="AQP46044">
        <property type="protein sequence ID" value="AQP46044"/>
        <property type="gene ID" value="RPIT_05990"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05990"/>
    <dbReference type="UniPathway" id="UPA00666"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07571">
        <property type="entry name" value="ALP_N-acyl_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01148">
        <property type="entry name" value="Lnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004563">
        <property type="entry name" value="Apolipo_AcylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045378">
        <property type="entry name" value="LNT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20154">
        <property type="entry name" value="LNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00546">
        <property type="entry name" value="lnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="CN hydrolase" evidence="9">
        <location>
            <begin position="200"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP46044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="496" mass="52618" checksum="99939B839FEA15FC" modified="2017-04-12" version="1">MLVSVALAVLTGILIGAGQAPLGVWPATILGVGLFTWLTAGCRPRAAFGLGLLTGLAMNTLTVSWVSVLGVWVGVALVGFLALWWGLLGLAVSRLTLLRPWVLLVPAAWVAMEFVSGKIPFGGFSWTRLAYTTIDQPLAGWLPWLGVTGVGYLVALVAQLGLQAIVSRQARLRAVVTALAAFLIGGLANLAPLAAASGEVSVAVVQPNVNRHEHGTASYARSVTNNALSETVFALAEARATGVELDFVVWPENATDVDPTTDATTRGLVELAVEIADLPIFVGAVMDGPSPDTRQTSSIWWDPATGPGAEYHKRDLVPFGEWIPFRDVLLPRLPILEQIGRQSIPGEGPGVVPAPVADRPGLEVGTIICFELAYDDTSYDVVRHGAQAVVSQSNTNTYGATFQPHQQLVINRVRAKEMGRDIAVATLNSLTGYVDARGNVHDVTDEFVSATRFMTLGLRDNVNASVRLSPWLAWIATIATVAGVAASLRRTGGTER</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIY3</accession>
    <name>A0A1Q2CIY3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_08320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08320"/>
    <dbReference type="EnsemblBacteria" id="AQP46086">
        <property type="protein sequence ID" value="AQP46086"/>
        <property type="gene ID" value="RPIT_08320"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08320"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021441">
        <property type="entry name" value="DUF3090"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11290">
        <property type="entry name" value="DUF3090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03847">
        <property type="entry name" value="TIGR03847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP46086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="175" mass="18782" checksum="D469C66EAED6C050" modified="2017-04-12" version="1">MAGMMLEFNRPDRCIVGTVGSPGNRLFLIQVAEGGQLAAVAIEKQQAQMLGIRIKEVLEQLAELGHDVPDEQPPADLGPLDAPLEVTFRAAAIGLAWDHERQRLLIELMAGPEDESDENALLQVLLTPAMAREFAARAEVVVASGRPPCPACGQPLEGSSHICPRANGYRGPLFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ35</accession>
    <name>A0A1Q2CJ35_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Vitamin K epoxide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">RPIT_09825</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VKOR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09825"/>
    <dbReference type="EnsemblBacteria" id="AQP46114">
        <property type="protein sequence ID" value="AQP46114"/>
        <property type="gene ID" value="RPIT_09825"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09825"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12922">
        <property type="entry name" value="VKOR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012932">
        <property type="entry name" value="VKOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041714">
        <property type="entry name" value="VKOR_Actinobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038354">
        <property type="entry name" value="VKOR_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07884">
        <property type="entry name" value="VKOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00756">
        <property type="entry name" value="VKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0874">Quinone</keyword>
    <keyword evidence="9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013360871" evidence="11">
        <location>
            <begin position="24"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="VKc" evidence="12">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP46114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="184" mass="20122" checksum="AE3016A6F56659B9" modified="2017-04-12" version="1">MLLFAIVSLVASAVLSIDAIKLAADPGADLACSINAILDCAKVGTTWQANVFGFPNAFLGLVSEPVVMTIAVASLVMVRFPRWFMFTANVCYLLGVIFAYWLLFQSSFVIGALCPWCLTVTLSTTFVFSSMTQWNILENNLFLSPSAQEKAVAFVKGGWFTIVLIGWLALVIFIEVLKFGFQII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ61</accession>
    <name>A0A1Q2CJ61_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_12250</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12250"/>
    <dbReference type="EnsemblBacteria" id="AQP46151">
        <property type="protein sequence ID" value="AQP46151"/>
        <property type="gene ID" value="RPIT_12250"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12250"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="145"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP46151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="362" mass="36151" checksum="0A0590B8CD61C4B7" modified="2017-04-12" version="1">MYSLGLLIHVEHAKGNYTAAGMVLAAFSVGMAVAGPIVSRQLSRFGTTFVLLLTLALSCAAFVGVALFPGLPLPAVMAMAAVGGAAMPPVIPTVRTLYPRLSPRNLLTALFSLDAALQEIIWVIGPVLITVLVAVFGSTTALLVVVAIQVAGGLVFALDPLVRQLRIPAATRKFGRVLSSPSVVLMVVVSLLMIGSFAAVEAAVVASFGEGSINAGIVLAISAVGSLLGGLAAGNRPIGRWSLALRLVIIVGGFGIAAVSSGFWGLAVALFVAGLGIAPALAAVSNIIAGSVSFAETAEAYGWIGTGQLLGASIGSATAGIAIDAAGGTGGIYVAAGIAVLAFVTALVFRTAQPDPSAPVID</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ70</accession>
    <name>A0A1Q2CJ70_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP46152">
        <property type="protein sequence ID" value="AQP46152"/>
        <property type="gene ID" value="RPIT_12430"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12430"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010290">
        <property type="entry name" value="TM_effector"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05977">
        <property type="entry name" value="MFS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="387"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="423" mass="44089" checksum="538F58A2C9284700" modified="2017-04-12" version="1">MRRLFADTRPLQTPDFRRLWVANIVTVIGAQLTVVAVPAQIYAITGSSGMVGLTGLFGLVPLIVFGLWGGALADHMDRRRLLAITTLGLIVTSGLFWVQAFLGLNNVWVLLTLFSLQQAFFGVNQPTRTAILPKLLPADQLPAANALNMTVMSAGAIAGPLVGGALIPVLGYSWLYFADTLTLLATLYAVWRLPPLPVDRPRGAPGLKSVVEGLRYLGAHQILLLSFVVDLIAMIFGMPRALFPQMAHVSFGGPAEGGLQFALLYAAMPAGAVLGGVFGGWVSRVSRHGLAVLWAIVVWGAAMAVMGAAVGLAPWATNAMLGLALGMLVIGGAADMASAAFRQSILLGATDDAVRGRLQGVFIVVVAGGPRLADVVHGGAAEVVGPAWATGGGGLLVLTGIAVVAVASPAFRRYRVDLNGRAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBE4</accession>
    <name>A0A1Q2CBE4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Polymorphic outer membrane protein repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_00140</name>
        <name evidence="7" type="ORF">SAMN05428934_10917</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ04842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00140"/>
    <dbReference type="EnsemblBacteria" id="AQP43426">
        <property type="protein sequence ID" value="AQP43426"/>
        <property type="gene ID" value="RPIT_00140"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ04842">
        <property type="protein sequence ID" value="SDZ04842"/>
        <property type="gene ID" value="SAMN05428934_10917"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00140"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007154">
        <property type="term" value="P:cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012332">
        <property type="entry name" value="Autotransporter_pectin_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003644">
        <property type="entry name" value="Calx_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005087">
        <property type="entry name" value="CBM_fam11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="GH16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03160">
        <property type="entry name" value="Calx-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03425">
        <property type="entry name" value="CBM_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00237">
        <property type="entry name" value="Calx_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="SSF141072"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544397" evidence="4">
        <location>
            <begin position="29"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="5">
        <location>
            <begin position="400"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1082"/>
            <end position="1103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ04842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="1272" mass="135586" checksum="B8BDE0AA0674A402" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBF0</accession>
    <name>A0A1Q2CBF0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00165</name>
        <name evidence="4" type="ORF">SAMN05428934_10911</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ04722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43431">
        <property type="protein sequence ID" value="AQP43431"/>
        <property type="gene ID" value="RPIT_00165"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ04722">
        <property type="protein sequence ID" value="SDZ04722"/>
        <property type="gene ID" value="SAMN05428934_10911"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00165"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544392" evidence="2">
        <location>
            <begin position="28"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ04722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="180" mass="18607" checksum="DDF5A9DDCF7B2C49" modified="2017-04-12" version="1">MSPKRIVVAAALSLLTACSPTADPSESVSESAQPTTVSPSASASPASSASASTSDYDWGAMPPRGFDTAPALTGSLPAQVGEWAGEPRVSDFGTVIDYKSGTKSVEADWWEQGQSTYKQAVEEMTDAAYVGENTCGTVDELFSVCIRVLANGAYKAQTLDLTVDELATLTDELIAAAVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBG6</accession>
    <name>A0A1Q2CBG6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00280</name>
        <name evidence="2" type="ORF">SAMN05428934_10510</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY83650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43447">
        <property type="protein sequence ID" value="AQP43447"/>
        <property type="gene ID" value="RPIT_00280"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY83650">
        <property type="protein sequence ID" value="SDY83650"/>
        <property type="gene ID" value="SAMN05428934_10510"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00280"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY83650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="111" mass="12207" checksum="55F0CDAA659377A6" modified="2017-04-12" version="1">MTNDQDVQARTASFLAHAREVEAILQEAGEVKWLQWISRAIADVEASRVAGFELVLAGFRGGMGSFNDFVIHPLNGHTVTRDAVEQVNDRLRREASAAVADARFVTRALGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBL5</accession>
    <name>A0A1Q2CBL5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aminotransferase DegT</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">dTDP-4-amino-4,6-dideoxygalactose transaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_00585</name>
        <name evidence="5" type="ORF">SAMN05428934_10570</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY85277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00585"/>
    <dbReference type="EnsemblBacteria" id="AQP43498">
        <property type="protein sequence ID" value="AQP43498"/>
        <property type="gene ID" value="RPIT_00585"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY85277">
        <property type="protein sequence ID" value="SDY85277"/>
        <property type="gene ID" value="SAMN05428934_10570"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00585"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY85277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="362" mass="38674" checksum="122A2D1FFE1DEEEF" modified="2017-04-12" version="1">MTEFIPPAKPIIGDEEREAVDRVLRSGMIAQGPEVAAFEQEFSEHFGLGRACVAVNSGTSGLHLGLLSSGIGAGDEVIVPSFTFAATANSVALTGATPVFADIALDDFTLDPESVEASITERTKAIMPVHLYGHPAKMDALQAIAEKHGLMLFEDAAQAHGAALNGTPVGAFGTFAMFSLYPTKNMTSGEGGMVSAANDEVERNLRLYRNQGMLQQYHNEVVGLNNRMTDIHAAIGRVQLTKVGAWTKQRQDNAAFLTANLDGVVPPSVADGAVHVYHQYTVRVEGDRDGMAKALKEEYNVGSGMFYPVPNHRLKPFMADVQLDNTEQAARECLSLPVHPSLSQGDLERIVEAVNAVAKAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBM2</accession>
    <name>A0A1Q2CBM2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)H-quinone oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Putative NAD(P)H quinone oxidoreductase, PIG3 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00615</name>
        <name evidence="3" type="ORF">SAMN05428934_10576</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY85442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00615"/>
    <dbReference type="EnsemblBacteria" id="AQP43502">
        <property type="protein sequence ID" value="AQP43502"/>
        <property type="gene ID" value="RPIT_00615"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY85442">
        <property type="protein sequence ID" value="SDY85442"/>
        <property type="gene ID" value="SAMN05428934_10576"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00615"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05276">
        <property type="entry name" value="p53_inducible_oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014189">
        <property type="entry name" value="Quinone_OxRdtase_PIG3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02824">
        <property type="entry name" value="quinone_pig3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY85442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="321" mass="33273" checksum="2E41D62DE747E99D" modified="2017-04-12" version="1">MRAVVVENPGDVDALTIQDVPTPEPGPGEVLVKTVASGVNRADVLQRQGHYPPPPGITDVIGLEASGVVEEVGQGVTRWRKGDEVVALLSGGGYAEFFVAPEGQLIPPPPGVDLVSAAGVLEVAATVVSNLKVGQLSPGETFLVHGGAGGIGTFATQYAKALGATVVATAGSDAKLQHCLAHGADHALDYHGDWVEALKAATGGADVILDIIGAKYLELNLKALKKRGRIVVIGLQGGVKGTLNLGALLSKQASIAATSLRFRPTDEKAEICAAVEAEVWPMLADGRIRLSPETRIPFDEVRRAHEQLTGGDNVGKIVLVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBN0</accession>
    <name>A0A1Q2CBN0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F5/8 type C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00690"/>
    <dbReference type="EnsemblBacteria" id="AQP43516">
        <property type="protein sequence ID" value="AQP43516"/>
        <property type="gene ID" value="RPIT_00690"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00690"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012704387" description="F5/8 type C domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="2">
        <location>
            <begin position="49"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="297" mass="31765" checksum="F9F4B71F86B57899" modified="2017-04-12" version="1">MAVSAAAALAVAGLAFPQTVANAAYEYTPISQDQMSVVEVDSVELTGEGTNGPGELALDGNIDTYWHTKWQGGIDPLPHHITVKLADEAVSLGRVHLTPRQSSNGSGRVHEYELHTAVGDCETATYAKVAEGSFPGEVATYSEVRTITLDEPVDATCAKVVYLSSWGGAKGSDPISPVEQVATLAEFNADTATDSGVDPTDPVGWAFNNLTYLPFMTRAQWANNPLGYTGTWTATDGSRWRTECDTALTGKNTCRTFRWTTVYNASPKPGGWLHVRPGEQVGVQQHGDAPTQLIGHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBN6</accession>
    <name>A0A1Q2CBN6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PemK-like, MazF-like toxin of type II toxin-antitoxin system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00730</name>
        <name evidence="3" type="ORF">SAMN05428934_10599</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00730"/>
    <dbReference type="EnsemblBacteria" id="AQP43524">
        <property type="protein sequence ID" value="AQP43524"/>
        <property type="gene ID" value="RPIT_00730"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86070">
        <property type="protein sequence ID" value="SDY86070"/>
        <property type="gene ID" value="SAMN05428934_10599"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00730"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY86070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="190" mass="22084" checksum="CC0A94FCF0F29D95" modified="2017-04-12" version="1">MARHPLVNGLTRILRDVATRAVDRAIQNNRRSARRTDAGDAPGRRPQPRRDARRQTTGYPGDYEQRPSIVYNPHKDGEPDPGEIVWTWVPYEEDYSQGKDRPVLLIGRDGDWLLGLQVTSQDKDDHREREARAGRYWINIGTGAWDHERRESEVRVNRIIRIDPDAVRRIGAILDEQRFNTVASEVERHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBR9</accession>
    <name>A0A1Q2CBR9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_00895</name>
        <name evidence="6" type="ORF">SAMN05428934_105131</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00895"/>
    <dbReference type="EnsemblBacteria" id="AQP43554">
        <property type="protein sequence ID" value="AQP43554"/>
        <property type="gene ID" value="RPIT_00895"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86914">
        <property type="protein sequence ID" value="SDY86914"/>
        <property type="gene ID" value="SAMN05428934_105131"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00895"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="10"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY86914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="332" mass="34767" checksum="48E45812BE3F2C06" modified="2017-04-12" version="1">MTPAANSARPTIYDVAREAGVSKSLVSLVLNDSPLVAPAKHAAVMAAIDKLGYRKSRAAANLASRRTKTVGLIIDDFQNPSFVDVLRGLRSALGPHGFHVAIREQQADDSSAVEGFLDSQVDALVIAAEPGRDLPDLGVPTVLEGTRLHDVDGADHVSSDQALGVRLLMQHLRSLGHIRIGHVTGLGGAAAERREAYAKFMASIGEAPRIAGEGNPTNEDGGYDGAVELLRSHPDVSAVFAANDAMALGVRAALREVGREVPADAALIGYDNSQFARSRFLDLTTVDNRGVDVGLACGEAILRRLSDPAAPPTSVTIPSRLVVRSSSASAPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBT8</accession>
    <name>A0A1Q2CBT8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00970"/>
    <dbReference type="EnsemblBacteria" id="AQP43567">
        <property type="protein sequence ID" value="AQP43567"/>
        <property type="gene ID" value="RPIT_00970"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00970"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025831">
        <property type="entry name" value="RecG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038475">
        <property type="entry name" value="RecG_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13749">
        <property type="entry name" value="HATPase_c_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HATPase_c_4" evidence="2">
        <location>
            <begin position="4"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="70"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="135" mass="14839" checksum="665048B6B1926246" modified="2017-04-12" version="1">MPLYARNPRIARVCADLGITRELGEGIRRLFSEMRERGLADPIYEQTSSSVKLTLIAVDALPAEVTARLTSSARAILTVLRLHQRPKGTGELADLSGVTRMTATRALAALEEEGIVTWRGNSKRDPRATWVLGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBV8</accession>
    <name>A0A1Q2CBV8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01090</name>
        <name evidence="4" type="ORF">SAMN05428934_105169</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43587">
        <property type="protein sequence ID" value="AQP43587"/>
        <property type="gene ID" value="RPIT_01090"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY87964"/>
        <property type="gene ID" value="SAMN05428934_105169"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01090"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544396" evidence="2">
        <location>
            <begin position="25"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY87964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="382" mass="39647" checksum="FD68AF99BF5EE279" modified="2017-04-12" version="1">MFKPILVLIGVTGLLVACATPGIEAPSVSPSATSSSDVATTSPTVPSAASTATSAAPTTPTIPGHATVDFTAGEPVALTAPSEMTGWGETLALPYGEFPGQVGVSPGGDGLEWGPSYGTQLPDGTWWILDTAHLRLAHYAEDGRYLDDALIPEEHLALGSYVQYQSPQALADGSVVLQSTTIDNPGLLRFSADAGFTRLDLPVHVGVRATDGRRLFGFNEAGAQVRVDPLNGDVAPVETFAGQAGAPYRLDVQPGLLHVQRGDLKLRIPLQSADEPAATVHPAVEAVTGSDGVLHILVTGIIEHADGEASDVSGLLSIDEEGRGTVQSVRPLTSSADPGDGAHLGIRLGNDRPWLMTVDDDALRVYGPLPELVESLPELVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBW6</accession>
    <name>A0A1Q2CBW6_9ACTN</name>
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        <submittedName>
            <fullName evidence="5">Uncharacterized lipoprotein YddW, UPF0748 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_00800</name>
        <name evidence="5" type="ORF">SAMN05428934_105113</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
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    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00800"/>
    <dbReference type="EnsemblBacteria" id="AQP43535">
        <property type="protein sequence ID" value="AQP43535"/>
        <property type="gene ID" value="RPIT_00800"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86427">
        <property type="protein sequence ID" value="SDY86427"/>
        <property type="gene ID" value="SAMN05428934_105113"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00800"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003790">
        <property type="entry name" value="GHL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02638">
        <property type="entry name" value="GHL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544412" evidence="2">
        <location>
            <begin position="26"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="GHL10" evidence="3">
        <location>
            <begin position="42"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY86427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="561" mass="61741" checksum="85B8FC02AC2D615B" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC27</accession>
    <name>A0A1Q2CC27_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43664">
        <property type="protein sequence ID" value="AQP43664"/>
        <property type="gene ID" value="RPIT_01600"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01600"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="93"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="202" mass="22255" checksum="8868285B688EF20E" modified="2017-04-12" version="1">MAGRHASPKSSERTLALTILVVGTVVSLASLVGGVWVVRAGVVVALIMAYAAVWAAWRELAAEKVRHNEELRHEMGMRAQQAQRFHEESVAMIGRFNARSENLQAVIAKLRRQLGAAKAELSSMRGNNAWLRAEVAERQARVEALETRIAELEAEDTGNIVALPRHVRPSIDDVWGEDEHPTMVDLAKLNLDGLPVHYAKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC69</accession>
    <name>A0A1Q2CC69_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_01825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01825"/>
    <dbReference type="EnsemblBacteria" id="AQP43702">
        <property type="protein sequence ID" value="AQP43702"/>
        <property type="gene ID" value="RPIT_01825"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01825"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032580">
        <property type="entry name" value="SatD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16264">
        <property type="entry name" value="SatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="211" mass="22208" checksum="8187E675A265D49A" modified="2017-04-12" version="1">MSRMKDLSAALLVDVVESRSADRGALHTAVLAAVEATNVAVAGTHPLHPTVGDELQGVYPTLGAALAASYSLRLELAPRWDVRFGIGGGEVLIVDAARGIQDGSAWWNAREAIDWVKEHSQRKGHESARTAIRDGRPTATPSADALARLVDAHLARLRDGAVGTLRGMLKGLDNAAIAAAEGISESANSQRVLNNDLRPLLDAMEALGSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC91</accession>
    <name>A0A1Q2CC91_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01955</name>
        <name evidence="4" type="ORF">SAMN05428934_11613</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000016">
        <property type="protein sequence ID" value="SDZ20352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43724">
        <property type="protein sequence ID" value="AQP43724"/>
        <property type="gene ID" value="RPIT_01955"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ20352">
        <property type="protein sequence ID" value="SDZ20352"/>
        <property type="gene ID" value="SAMN05428934_11613"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01955"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544417" evidence="2">
        <location>
            <begin position="26"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ20352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="211" mass="22554" checksum="D22B629A9E2BF3CF" modified="2017-04-12" version="1">MRRIALSLMCVGLLVACTPEEPVQTSLPPTSTVSTVSTPSPSPTTSAPSAVATPSPSPSPTAVESFPPPPATESPEQAAVRAAWTEYYTQFAKYAADPGLGDLTELTMLVTDEELPETLGQVQRLRGANEVLTEGFRFRDVVVTIPHPDSGAVDSALVAYCFDRSGLQVQDSESGEVIPRSLSNMEEQATLERGSDGRWRIASIRNRESSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCE4</accession>
    <name>A0A1Q2CCE4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Resolvase, N terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_02290</name>
        <name evidence="5" type="ORF">SAMN05428934_10157</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the site-specific recombinase resolvase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY23999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02290"/>
    <dbReference type="EnsemblBacteria" id="AQP43788">
        <property type="protein sequence ID" value="AQP43788"/>
        <property type="gene ID" value="RPIT_02290"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY23999">
        <property type="protein sequence ID" value="SDY23999"/>
        <property type="gene ID" value="SAMN05428934_10157"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02290"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Homeobox-like_sf"/>
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        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RECOMBINASES_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="80"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY23999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="109" mass="11938" checksum="D062CCE20C145F41" modified="2017-04-12" version="1">MARLMLQVLGAFAEFERNLIKERQAEGIRLAKAAGRYKGRAPKLTAEQLNTAQEKIAAGVSKARVARDLAVDRSTLYRALQRSQASHKSDASVSRNLAAKEEQGEAGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCE6</accession>
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        <submittedName>
            <fullName evidence="3">Type IV secretion system protein VirD4</fullName>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY23599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02220"/>
    <dbReference type="EnsemblBacteria" id="AQP43774">
        <property type="protein sequence ID" value="AQP43774"/>
        <property type="gene ID" value="RPIT_02220"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY23599">
        <property type="protein sequence ID" value="SDY23599"/>
        <property type="gene ID" value="SAMN05428934_10143"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02220"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
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        <property type="entry name" value="TraG-D_C"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TraG-D_C" evidence="1">
        <location>
            <begin position="291"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY23599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="479" mass="51108" checksum="DC5F8CB92DD87925" modified="2017-04-12" version="1">MRGRFEPTAVGWRIGTSKVPVGVALWQPWDRTAGVIGPQGSGKTLDILTPALLQAPGAALVTLTKPDDLLLTLATRQARGPVAVLDPFGAAPGLPELIWDPIDGCVDATVAEKRAKAFCAGTLGSGGDGADSAARFYAAEAAKVIQCYLHAAALAGYTLNDVLEWSANPRTATLPSEILRSHPMAEPNWSGLLTGAVSNTDERTAGNTKSTVDQALALFATRARRERCVPSDGRPAVDIADLIRRNGTIYLLGREDPYVSASPLMTAVAEHVLDTALQLANESGFGRLCPPMLACLDELPSTAPLPTLATRMANERALGISFIWASQTWAQLTRIFGEQQARAIKDLTNSLIIFGGSKDAGFNREISDLLGTRRITRRNHQHGGHGSISTHGEDTPVIRPEQLRELPARTALVVAENGKPILATLHRAIDGKPGKHLLDQQRQARRLLTTSEGAAPHPMTAGEKTALAHSYSRQLGLTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCH5</accession>
    <name>A0A1Q2CCH5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">C-type cytochrome biogenesis protein CcsB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Cytochrome c-type biogenesis protein CcsB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_02445</name>
        <name evidence="9" type="ORF">SAMN05428934_10187</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY24918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02445"/>
    <dbReference type="EnsemblBacteria" id="AQP43818">
        <property type="protein sequence ID" value="AQP43818"/>
        <property type="gene ID" value="RPIT_02445"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY24918">
        <property type="protein sequence ID" value="SDY24918"/>
        <property type="gene ID" value="SAMN05428934_10187"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02445"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002541">
        <property type="entry name" value="Cyt_c_assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017562">
        <property type="entry name" value="Cyt_c_biogenesis_CcsA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045062">
        <property type="entry name" value="Cyt_c_biogenesis_CcsA/CcmC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30071">
        <property type="entry name" value="PTHR30071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01578">
        <property type="entry name" value="Cytochrom_C_asm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03144">
        <property type="entry name" value="cytochr_II_ccsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_C_asm" evidence="7">
        <location>
            <begin position="106"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP43818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY24918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="302" mass="33352" checksum="A47CCD11DCF58BEB" modified="2017-04-12" version="1">MLEWAEYLVTAAAVFVLLGLISDIVLVTSRKRRPVARQAQSRATVSVGGGPLEATEPPPAVTVKEKRSSLSWYATAFEVIAIVLLTVYMAVRAGVTGHGPFANQHEFAVAFTWGILVVNLFFELKYRVRMLSLIVLPVAAVMLVYALSLDTGVRPLIPALQNNLLLSLHVGFAIIAYGAACVSFGAAVLYLVKPMMRRLPLPREEVLDDVGYRAAVVTFPLLTIMIVLGSVWAETAWGRYWGWDPKETAALVTWLVYGAFLHARVVRDWRGRRAAWLLVLGFLTVLFAYFGNHFFGGLHSYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCJ5</accession>
    <name>A0A1Q2CCJ5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">o-succinylbenzoate synthase</fullName>
            <shortName evidence="4">OSB synthase</shortName>
            <shortName evidence="4">OSBS</shortName>
            <ecNumber evidence="4">4.2.1.113</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">4-(2'-carboxyphenyl)-4-oxybutyric acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">o-succinylbenzoic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">menC</name>
        <name evidence="6" type="ORF">RPIT_02580</name>
        <name evidence="7" type="ORF">SAMN05428934_101116</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
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    <reference evidence="6" key="3">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
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            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(1R,6R)-6-hydroxy-2-succinyl-cyclohexa-2,4-diene-1-carboxylate = 2-succinylbenzoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:10196"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18325"/>
            <dbReference type="ChEBI" id="CHEBI:58689"/>
            <dbReference type="EC" id="4.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 4/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.</text>
    </comment>
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        <property type="protein sequence ID" value="AQP43839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="1610493.RPIT_02580"/>
    <dbReference type="EnsemblBacteria" id="AQP43839">
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        <property type="gene ID" value="RPIT_02580"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY25749">
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        <property type="gene ID" value="SAMN05428934_101116"/>
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        <property type="reaction ID" value="UER00165"/>
    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
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    </dbReference>
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    <feature type="domain" description="MR_MLE" evidence="5">
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            <begin position="79"/>
            <end position="175"/>
        </location>
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            <position position="97"/>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP43839.1"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY25749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="315" mass="33297" checksum="A5A87258080157B9" modified="2017-04-12" version="1">MTPFVYDIALSVPFRGLSRRSGVLFEGPAGWAEWSPFPEYGDQEAAEWLRSALETATHGHPATVRDRVEVNGIVPALSPADAAARAVTSGCRTIKIKVAAPGDPVADDVARVAAVREALPSARLRVDANGGWTLAQAAEALRLLEPMGLEYAEQPCATFGELASLRAMETGVLIAADESIRRADDPYRVRDAGAADVAVLKVQPLGGARACLRLADELGLPVVVSSAVETSVGLASGLALAGALPDLPFACGLETGRLLAGDVATEPLVPDDGWLVVRDVTPDPALLRVHRAGPDLTSFWLDRWERVSRIVEDQG</sequence>
</entry>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11 13">RP1</strain>
        </source>
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        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="SDY27189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP43880">
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    </dbReference>
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        <property type="protein sequence ID" value="SDY27189"/>
        <property type="gene ID" value="SAMN05428934_101167"/>
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        </location>
    </feature>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="596" mass="64131" checksum="CC2D0051E6EB670C" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY32097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03620"/>
    <dbReference type="EnsemblBacteria" id="AQP44014">
        <property type="protein sequence ID" value="AQP44014"/>
        <property type="gene ID" value="RPIT_03620"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY32097">
        <property type="protein sequence ID" value="SDY32097"/>
        <property type="gene ID" value="SAMN05428934_101325"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03620"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY32097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="111" mass="12364" checksum="06EB0CDFCA3FB7B0" modified="2017-04-12" version="1">MIVRIMGQGQWVLEPEHLLELNELDRALEERVEAGDQEGMIAALERLGEGVRRLGVEVPEDVLAESDLVLPDVDVSVEEVRALLQSTSEYYGLIPDADDELYEGDPESTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD35</accession>
    <name>A0A1Q2CD35_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Dihydrolipoamide dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="12">Dihydrolipoyl dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_03585</name>
        <name evidence="13" type="ORF">SAMN05428934_101318</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="7">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY31886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03585"/>
    <dbReference type="EnsemblBacteria" id="AQP44007">
        <property type="protein sequence ID" value="AQP44007"/>
        <property type="gene ID" value="RPIT_03585"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY31886">
        <property type="protein sequence ID" value="SDY31886"/>
        <property type="gene ID" value="SAMN05428934_101318"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03585"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016668">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 9" id="KW-0274">FAD</keyword>
    <keyword evidence="2 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="11">
        <location>
            <begin position="5"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="10">
        <location>
            <begin position="345"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="443"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="177"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="8">
        <location>
            <begin position="42"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP44007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY31886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="466" mass="47837" checksum="E7A0F2527991A63D" modified="2017-04-12" version="1">MSDAYDLAILGAGSAGYACALRAATLGLSVVMIDEAEVGGTCLHRGCIPTKAWLHAAKVRRTVSKAPSFGIGAELGDTDAEAIRAYADGVVSGLHRGLTGLLKSRGVTVVAARGSLEVSDAGPAIRTPDALHRASAVLVATGAAPATLGFDIDGERILTSNHALRLSTLPETAIVLGGGVIGVEFASLWADLGVSVTLLEATDRLLPGEEPGHVRVLRRELERRGVDIRLGAPATSAEATDGGVRVSAGSDSVSAELLLIAAGRRPVTSGIGLEEAGVTLSPSGHVVVDGNLQTAARNVYAAGDLVPGPQLAHRGYAHGIFVAERIAHNLGRHPRKPTPVRDVDIPRVVYSSPQLASVGVTLEAAGAGADSVDYHLTGNGRAQILRAPGERESGVVRMVRAADGRIVGLHAVGEDVSELIAEGALLVGWHATPEDVAGIIHPHPTLSEALAEANWALAGQPLHIHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD36</accession>
    <name>A0A1Q2CD36_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">IMP dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Inosine 5-monophosphate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_03700</name>
        <name evidence="9" type="ORF">SAMN05428934_101342</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IMPDH/GMPR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY32585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03700"/>
    <dbReference type="EnsemblBacteria" id="AQP44028">
        <property type="protein sequence ID" value="AQP44028"/>
        <property type="gene ID" value="RPIT_03700"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY32585">
        <property type="protein sequence ID" value="SDY32585"/>
        <property type="gene ID" value="SAMN05428934_101342"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03700"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00381">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005990">
        <property type="entry name" value="IMP_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005991">
        <property type="entry name" value="IMP_DH-rel1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000130">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01303">
        <property type="entry name" value="IMP_DH_rel_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0630">Potassium</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="7">
        <location>
            <begin position="91"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="7">
        <location>
            <begin position="153"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="245"/>
            <end position="247"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="303"/>
            <end position="305"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY32585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="486" mass="51217" checksum="90A8F6276DA68EA9" modified="2017-04-12" version="1">MRFLHGDPGYDLTYSDVFMVPSRSAVSSRLDVDLTSTDGLATPIPLVAANMTAVSGRRMAETMARRGGLAIFPQDIPSDVVAKSISKVKRAHPIFDAAVTVALDTTVGETLSLIGKRAHGVAVVIDEDRRVLGLVSPQDAAGSDRFAQARDVMTTDVTRVSVSSSPAEVFDVLSEQHQKVAVAVDDGGALVGLMTPKGALRSAIYSPALDHEGRLRAGVAVGINGDIPSKVRAALDAGADVLVMDTAHGHQDKMIGALEAARVERDRFAGETGRTVLIVAGNVVTAEGVNDLINAGADILKVGVGPGAMCTTRMQTGVGRPQFSAVLECAAAAKERGKSIWADGGVRHPRDVALALAAGAGSVMIGSWFAGTHESTGDQLTDSQGRAYKESFGMASARAVRNRTREYSAFDRARAAMFEEGISSSRMYLDPRRPGVEDLLDWITSGVRSSCTYAGARSLEEFAERAVVGVQSGSGYEEGRPLDQSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD42</accession>
    <name>A0A1Q2CD42_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">1-acyl-sn-glycerol-3-phosphate acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_03780</name>
        <name evidence="4" type="ORF">SAMN05428934_101358</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY33023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03780"/>
    <dbReference type="EnsemblBacteria" id="AQP44043">
        <property type="protein sequence ID" value="AQP44043"/>
        <property type="gene ID" value="RPIT_03780"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY33023">
        <property type="protein sequence ID" value="SDY33023"/>
        <property type="gene ID" value="SAMN05428934_101358"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03780"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="2">
        <location>
            <begin position="35"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY33023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="252" mass="26990" checksum="97A7DBBB6A338A2D" modified="2017-04-12" version="1">MWYRLFKFAIFRPLVKYGYGARLIGAENFPRQGGAILASNHIGALDSLVIPAMVPRPLRFPAKAELFSGDGGLGAKIIAWFLKRIDMVPIDRTGGRASADALGAISDTLAEGNVVAIYPEGTRSPDGRLYKGKTGMARIALQNRVPVIPVGVVGTKSRKGPLGIPWVTRPLVIIGEPLDFSAYAGTPGNTRVLRWVTDETLAAIQQLTGQEYADVYAARVKQGDLAERGSDDFVIPRPGGGEPPQPAVENVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD45</accession>
    <name>A0A1Q2CD45_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methylamine utilisation protein MauE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03755</name>
        <name evidence="3" type="ORF">SAMN05428934_101353</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY32878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03755"/>
    <dbReference type="EnsemblBacteria" id="AQP44038">
        <property type="protein sequence ID" value="AQP44038"/>
        <property type="gene ID" value="RPIT_03755"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY32878">
        <property type="protein sequence ID" value="SDY32878"/>
        <property type="gene ID" value="SAMN05428934_101353"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03755"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY32878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="459" mass="47453" checksum="AA4A99E0EC319708" modified="2017-04-12" version="1">MTFLTLASLTLAFLLAVSGIAKLRSPAATREAFTALRLPEVLRRSPAPAALPWLELLLAVVLAAGVGWLLIGGAVAALALFVAYTVVIGRALGFDEPVRCACFGTLGTHDVSTRTLVRNVVLVLLAVAAVVAAVLDQSVYTLGASGWGWVAVAALASAAVALSLGGAPGPVAGDGPGWLGGAVVTHVASGESIGIRSLAARHDGVVLLFVLAGCGSCERVIADLPEWRQRHPGREVVVLRAPGQMSDGWADLDLYEDPGFNLARALSGGYTPTAVELGRDGAPVGKVAVGYEPVTALLNATATPAPPEDESEAKQQEVEADYVRRPIPDVVLLRSDGEPATARALASQQAQLLVGIDCLCTPAREAIDRLSEWQERLPILQVSLVVPFTMGGSELTERQGVIALYDHEGIASRALGLSGNVSAVLLGADGGLAGGPVSGLDEVEAFVSEIEEQIRLAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD74</accession>
    <name>A0A1Q2CD74_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="3">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_03795</name>
        <name evidence="5" type="ORF">SAMN05428934_101361</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the class-II DAHP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY33104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03795"/>
    <dbReference type="EnsemblBacteria" id="AQP44046">
        <property type="protein sequence ID" value="AQP44046"/>
        <property type="gene ID" value="RPIT_03795"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY33104">
        <property type="protein sequence ID" value="SDY33104"/>
        <property type="gene ID" value="SAMN05428934_101361"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03795"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00084"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002480">
        <property type="entry name" value="DAHP_synth_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21337">
        <property type="entry name" value="PTHR21337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01474">
        <property type="entry name" value="DAHP_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01358">
        <property type="entry name" value="DAHP_synth_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY33104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="461" mass="50522" checksum="1D57BB4946FAE479" modified="2017-04-12" version="1">MSSIMSREELRALPLVQQPTYSDPESLDRTITALESLPPLVFAGECDDLRLKMADVAEGKAFLLQGGDCAETFAAVTAGDIKGKLLVQLSMAVVMTYAAQVPVVKVGRIAGQYAKPRSKDTETRGDVTLPAYRGDAINGFEFTEESRAHDPGRLLQVYNSSAATLNLVRAFVKGGFADLRGVHSWNAQFVRDSAVEAAYEELASEIDHALAFMVACGVQDDSLSTVDFYASHEALLLEYERALTRVDSRSEQLYGCSGHMLWIGERTRQLDGAHVELLRRVQNPLGVKLGPTTTPEQALALADRLDPDRVPGRLTFITRMGARKVRDVLPGIIEGVEASGRKVAWVCDPMHGNTFEAANGYKTRSFADVVDEVHGFFDVHEQLGTWPGGLHVELTGDDVTECVGGVHNLGEADLSSRYETVCDPRLNRNQSLELAFTVAQRLRSGRLNRVNPVQEFKAKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD75</accession>
    <name>A0A1Q2CD75_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Colanic acid biosynthesis glycosyltransferase WcaL</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Glycosyltransferase involved in cell wall bisynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_03920</name>
        <name evidence="7" type="ORF">SAMN05428934_101388</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY33766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03920"/>
    <dbReference type="EnsemblBacteria" id="AQP44068">
        <property type="protein sequence ID" value="AQP44068"/>
        <property type="gene ID" value="RPIT_03920"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY33766">
        <property type="protein sequence ID" value="SDY33766"/>
        <property type="gene ID" value="SAMN05428934_101388"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03920"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="5">
        <location>
            <begin position="27"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="4">
        <location>
            <begin position="221"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="398"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="398"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="426"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY33766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="440" mass="46652" checksum="C13FEFFA09733DD3" modified="2017-04-12" version="1">MSRIGYVLKVYPRFSETFIVTEILAREAHGDDISIYALRPTTDARFHPEIARVKGGVTWISRYPKGADLWARIADAVTDEAMRERFAAILPELATLPGDEVAQGVELAQAVAADGITHLHAHFATLAGRMAWIASKLTGVPYTMTTHAKDIYHESVDAAWLRRLCADADRVIAISRFNDAYLAGVLEGTDSRVSLQYNALELDRFPYREPASAGEVLRVSAVGRLVPKKGFGDLISAAALLRDAGVPVDVTIAGDGDLTAQLNAQIASLDLSDNVRLIGPQTQSEIRVLIAGSDVFAAPCVPGEDGNIDGLPTVVLESMAIGTPVIGTAVTGLPEVILDGETGVLLEPGDVDGLAAALKAFADGSVPAQAMAANARALIEDQFDSRRQAATLSAWQTGASPRSLSVAGEERTSSHGSFVAARSATASDDEGRRELQEVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD78</accession>
    <name>A0A1Q2CD78_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 28</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Predicted glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03925</name>
        <name evidence="3" type="ORF">SAMN05428934_101389</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY33791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03925"/>
    <dbReference type="EnsemblBacteria" id="AQP44069">
        <property type="protein sequence ID" value="AQP44069"/>
        <property type="gene ID" value="RPIT_03925"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY33791">
        <property type="protein sequence ID" value="SDY33791"/>
        <property type="gene ID" value="SAMN05428934_101389"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03925"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_tran_28_C" evidence="1">
        <location>
            <begin position="232"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY33791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="400" mass="43549" checksum="D492E3C30BF82735" modified="2017-04-12" version="1">MDETTPIRVLLYSHDSQGLGHVRRNLAIAHHLARVIPEETGRPVSGLLVSGLPRASRFPLPQGFDWLTIPGIAKGEDGYHARFLGTATKDLINLRSSVLEATLLGFMPDLVIIDRHIYGVRKELRRPLRRLREAKPEARVVLGLREVLDEPEVVAAEWKRLKNPMKLRELVDEVWIYGDRAVHDPIATGEAPPALIDRLRFTGYLASGRADAPAGEEGLAENPPFILTTTGGGSDGMDLLRAAVAIDVPEGHQHLVVTGPQLGEDEVAEIQALAGERTVVHAALPGLVEHIENASAVIAMGGYNTVCEILATDTPGLIVPREVPRLEQLIRARAMERAGAMELMRADDVTTDALSAWVADAVNRRADRSHVERDGLDVTAHYAAELLQRASVRELVGASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDB0</accession>
    <name>A0A1Q2CDB0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleotide-binding protein RPIT_04195</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04195</name>
        <name evidence="3" type="ORF">SAMN05428934_101443</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Displays ATPase and GTPase activities.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RapZ-like family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY35425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04195"/>
    <dbReference type="EnsemblBacteria" id="AQP44112">
        <property type="protein sequence ID" value="AQP44112"/>
        <property type="gene ID" value="RPIT_04195"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY35425">
        <property type="protein sequence ID" value="SDY35425"/>
        <property type="gene ID" value="SAMN05428934_101443"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04195"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00636">
        <property type="entry name" value="RapZ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005337">
        <property type="entry name" value="RapZ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30448">
        <property type="entry name" value="PTHR30448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03668">
        <property type="entry name" value="ATP_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005052">
        <property type="entry name" value="P-loopkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="14"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="63"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY35425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="288" mass="31966" checksum="411BD7B6679430B2" modified="2017-04-12" version="1">MTDAAPLEFALITGLSGAGRRTAAHTMEDLGWYVVDNLPPEMLPSLAEILRGFGVRRLAVVADVRSREQFERLPAAIEQLKSDGAVVTSLFLEATDDVIVQRQESNRRPLPLQGGDRLIEGIERERRLLADLRADADIVVDTSYISARQLAQRVANHFGDEATDKLKVAIISFGFKNGVPIDADMVFDVRFLPNPFWIPELRPKSGLSKDVAQYVLKHDAAKRFQDHMVELIETVSPGYLKEGKRHVTVAIGCTGGKHRSTSMGEELSERLRAKGFPTTVLHRDLGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDK7</accession>
    <name>A0A1Q2CDK7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribonuclease J</fullName>
            <shortName evidence="9">RNase J</shortName>
            <ecNumber evidence="9">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rnj</name>
        <name evidence="12" type="ORF">RPIT_04660</name>
        <name evidence="13" type="ORF">SAMN05428934_101539</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer, may be a subunit of the RNA degradosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04660"/>
    <dbReference type="EnsemblBacteria" id="AQP44194">
        <property type="protein sequence ID" value="AQP44194"/>
        <property type="gene ID" value="RPIT_04660"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37818">
        <property type="protein sequence ID" value="SDY37818"/>
        <property type="gene ID" value="SAMN05428934_101539"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04660"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01491">
        <property type="entry name" value="RNase_J_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004613">
        <property type="entry name" value="RNase_J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042173">
        <property type="entry name" value="RNase_J_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030854">
        <property type="entry name" value="RNase_J_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041636">
        <property type="entry name" value="RNase_J_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17770">
        <property type="entry name" value="RNase_J_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004803">
        <property type="entry name" value="RnjA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00649">
        <property type="entry name" value="MG423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="4 9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="11">
        <location>
            <begin position="27"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9 10">
        <location>
            <begin position="371"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR004803-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP44194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY37818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="558" mass="60779" checksum="50FF922A27E856C1" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDP3</accession>
    <name>A0A1Q2CDP3_9ACTN</name>
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        <submittedName>
            <fullName evidence="3">Glyoxylase, beta-lactamase superfamily II</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">RPIT_04960</name>
        <name evidence="3" type="ORF">SAMN05428934_101598</name>
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        <name type="scientific">Tessaracoccus flavus</name>
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            <taxon>Bacteria</taxon>
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    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="21"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
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            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY39338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="262" mass="27506" checksum="323DB67B49EFBF64" modified="2017-04-12" version="1">MTLNWTPVTARVLVAAVEPHRVNVGLIVGENEAMLIDSGNDAAQGAAILESAGAVAGVPVTRVALTHHHDDHVGGLAGMPGLEAIAHEHLDSDAITRRFSMALAVDLGGQRVELLHFGDAHTRSDVVVFVPGENVVFAGDLLEEGADPQVDESSSLSNWPTVLDGVLGATNDRTLFVPGHGAAMDRDVAFVQRAEIAMLYSQTEMLIQQGVSVEDAASATEWPFGAETLATALPKAYDELAARGITPKRQLPISALAPRSGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDR0</accession>
    <name>A0A1Q2CDR0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Zinc transport system ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_05070</name>
        <name evidence="6" type="ORF">SAMN05428934_101620</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY39907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05070"/>
    <dbReference type="EnsemblBacteria" id="AQP44262">
        <property type="protein sequence ID" value="AQP44262"/>
        <property type="gene ID" value="RPIT_05070"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY39907">
        <property type="protein sequence ID" value="SDY39907"/>
        <property type="gene ID" value="SAMN05428934_101620"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05070"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="7"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY39907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="250" mass="26333" checksum="54D4E84E5A0D1111" modified="2017-04-12" version="1">MNATDPLRADGLYVSLGGLPILRDVSLRVGAGEAVALLGGNGSGKTTLIRTLLGLVPHQEGTVELFGEAVPGFTDWSRVGYVPQHSAVAVANATVREVAASGRLAHRRPFQWLTRADRMALDDALAHVGLADRKGWPFGALSGGQKQRVLIARALASQPDLLVMDEPMAGVDLHSQAGLARLLTSFARDGLALLVVLHEQGPLAGMLDRTITLCDGRVVDPEHPTAHDCAPATPWESPVGLSDPFAGAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDT7</accession>
    <name>A0A1Q2CDT7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_04945</name>
        <name evidence="2" type="ORF">SAMN05428934_101595</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY39259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04945"/>
    <dbReference type="EnsemblBacteria" id="AQP44240">
        <property type="protein sequence ID" value="AQP44240"/>
        <property type="gene ID" value="RPIT_04945"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY39259">
        <property type="protein sequence ID" value="SDY39259"/>
        <property type="gene ID" value="SAMN05428934_101595"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04945"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009784">
        <property type="entry name" value="DUF1349"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35332">
        <property type="entry name" value="PTHR35332"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07081">
        <property type="entry name" value="DUF1349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY39259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="192" mass="20561" checksum="2E524C3A24E9AE5E" modified="2017-04-12" version="1">MTNAAWSAGTWSHPPTAVVERGSDLLVTAAEGSDAWRITSYGFVHDSEHALLAPFAVDSAVEVEFTADFTSQFDQAGVFVRVSAEHWVKAGVEFSDGAPQLGAVVTSPRSDWSLAPVPHWAGTRVLVRVSRSDGALTIRARSGDGDLQLVRVVPFEDGMEASAGPFVCAPTRAGLTVTLHAWRIEKPDHSLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDV4</accession>
    <name>A0A1Q2CDV4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endoribonuclease YbeY</fullName>
            <ecNumber evidence="7">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ybeY</name>
        <name evidence="8" type="ORF">RPIT_05000</name>
        <name evidence="9" type="ORF">SAMN05428934_101606</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the endoribonuclease YbeY family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY39552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05000"/>
    <dbReference type="EnsemblBacteria" id="AQP44250">
        <property type="protein sequence ID" value="AQP44250"/>
        <property type="gene ID" value="RPIT_05000"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY39552">
        <property type="protein sequence ID" value="SDY39552"/>
        <property type="gene ID" value="SAMN05428934_101606"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05000"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00009">
        <property type="entry name" value="Endoribonucl_YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023091">
        <property type="entry name" value="MetalPrtase_cat_dom_sf_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002036">
        <property type="entry name" value="YbeY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020549">
        <property type="entry name" value="YbeY_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02130">
        <property type="entry name" value="YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00043">
        <property type="entry name" value="TIGR00043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01306">
        <property type="entry name" value="UPF0054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 7" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY39552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="153" mass="17003" checksum="ED6F4800F5A0A0CE" modified="2017-04-12" version="1">MIDLNNESGVEADELGLVALARFALEKLRIHPQAELSILLVDEATMADYHERFMDLPGPTDVMSFPMDELRAPNDDEEPPLGLLGDIVLCPQVTERQAADNGRAPDAEAEYLLIHGLLHLLGHDHAEPEEKAVMFGLNDRIIAAWELAKQERT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDV5</accession>
    <name>A0A1Q2CDV5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide chain release factor 2</fullName>
            <shortName evidence="4">RF-2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">prfB</name>
        <name evidence="7" type="ORF">RPIT_05290</name>
        <name evidence="8" type="ORF">SAMN05428934_1035</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="4">Methylated by PrmC. Methylation increases the termination efficiency of RF2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY65128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05290"/>
    <dbReference type="EnsemblBacteria" id="AQP44299">
        <property type="protein sequence ID" value="AQP44299"/>
        <property type="gene ID" value="RPIT_05290"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY65128">
        <property type="protein sequence ID" value="SDY65128"/>
        <property type="gene ID" value="SAMN05428934_1035"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05290"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00094">
        <property type="entry name" value="Rel_fac_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004374">
        <property type="entry name" value="PrfB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
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    <proteinExistence type="inferred from homology"/>
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            <begin position="244"/>
            <end position="260"/>
        </location>
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        <location>
            <begin position="69"/>
            <end position="115"/>
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        <location>
            <position position="251"/>
        </location>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP44299.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY65128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="370" mass="40896" checksum="4B0115CD81A1FC74" modified="2017-04-12" version="1">MASDDLSTRISDLGRSLDSIEAVADLPKLRSEIGELEQQVAAPDLWDDQENAQRITSQLSAKQGEVDRLVSLRSRLDDAELMLGMAEDEGDAETRQEVAGELERLARDIATLEVRTLLSGDYDPRDALITIRAEAGGVDAADFAEMLMRMYLRWADRHGYATEVYDTSYAEEAGLKSATFAVKAPFAYGTLSVEQGTHRLVRISPFDNQGRRQTSFAGVEVLPVTEETDHIDIPEAELRIDVFRSSGPGGQSVNTTDSAVRITHLPTGIVVSCQNEKSQLQNKAAALRVLQSRLLERARSEREKELNALKGDGGNSWGAQMRSYVTHPYQMVKDLRTEHEVGNPDAVFDGDIDGFIDAGIRWRKKTEAQA</sequence>
</entry>
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        <name type="scientific">Tessaracoccus flavus</name>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">RP1</strain>
        </source>
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                <person name="Peterson S.W."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05475"/>
    <dbReference type="EnsemblBacteria" id="AQP44331">
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR004017">
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        <location>
            <begin position="7"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="CCG" evidence="1">
        <location>
            <begin position="138"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="AQP44331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY66212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
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            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="250" mass="26886" checksum="7352B087590F0726" modified="2017-04-12" version="1">MSSSPHVALFATCITDTMKPSIPIATVTLLERLGCRVSYPEKQTCCGQIMTNTGYFDEAMPTVRNYVASFSEFDYIVAPSGSCVGSVREQHPMLATRSGDAGLAREASSVASRTYELTEFIVDVLGVTDVGAYFPHRVTYHPTCHSLRVAKVGDRPLRLLSEVRGLELVDLPDAEQCCGFGGTFSLKNSDVSIAMATDKADHVAGTGAEYLVAADHACLMNIGGVLHRKKAPVTTIHLAEILAATEEDPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE54</accession>
    <name>A0A1Q2CE54_9ACTN</name>
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    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="protein sequence ID" value="SDY67883"/>
        <property type="gene ID" value="SAMN05428934_103107"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR007438">
        <property type="entry name" value="DUF488"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF04343">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF024492">
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY67883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="170" mass="18762" checksum="E1F3209B096E91BF" modified="2017-04-12" version="1">MLFTIGHSTHTLEEFVALLRQHAVDLLVDIRTVPRSRTNPQYNLDSLPGSLAAQGIGHEYLASLGGLRKGVPDSPNGAWRNKSFKAYADHMLSAEFAEGIEELTARTQQHTVAIMCAEAVWWRCHRSLVAEAMLVRGHEVSHIMPDGRATPATLRDFAVVDGTTITYPET</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE77</accession>
    <name>A0A1Q2CE77_9ACTN</name>
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    <organism evidence="3 5">
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    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY69219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06070"/>
    <dbReference type="EnsemblBacteria" id="AQP44432">
        <property type="protein sequence ID" value="AQP44432"/>
        <property type="gene ID" value="RPIT_06070"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY69219">
        <property type="protein sequence ID" value="SDY69219"/>
        <property type="gene ID" value="SAMN05428934_103160"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0005576">
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
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        <property type="entry name" value="Esterase_phb"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544445" evidence="2">
        <location>
            <begin position="26"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY69219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="536" mass="57105" checksum="EB8DDF0D9FBD31A9" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE91</accession>
    <name>A0A1Q2CE91_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pimeloyl-ACP methyl ester carboxylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05935</name>
        <name evidence="3" type="ORF">SAMN05428934_103133</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44411">
        <property type="protein sequence ID" value="AQP44411"/>
        <property type="gene ID" value="RPIT_05935"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68550">
        <property type="protein sequence ID" value="SDY68550"/>
        <property type="gene ID" value="SAMN05428934_103133"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05935"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="40"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY68550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="261" mass="28189" checksum="84C61A526309B4FE" modified="2017-04-12" version="1">MPDSDAPEITHQSAEHWFICDDYELRILEFDGPGGTVPTFVLVHGIGVSSLYMAPLAEKLAAHGRVLLMDLPGFGGVPQPEDDLDVEGFARVIRSGLEALKASRVVMIGHSMGAQFVVELALLAPEFGGRVVLVAPVVPPGSRDTRTVLADFIRSSFSERLPAAMLSVQGYLQTAPSWVAAVFPAMLEYRIERRIEGLKGRLAILRGDEDVLCTDEWVDELARAARGCEVTTTLVEGASHQVVVDHADWVVAAALDVCETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEA7</accession>
    <name>A0A1Q2CEA7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AAA family ATPase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Recombination protein MgsA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_06250</name>
        <name evidence="6" type="ORF">SAMN05428934_103195</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06250"/>
    <dbReference type="EnsemblBacteria" id="AQP44462">
        <property type="protein sequence ID" value="AQP44462"/>
        <property type="gene ID" value="RPIT_06250"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70123">
        <property type="protein sequence ID" value="SDY70123"/>
        <property type="gene ID" value="SAMN05428934_103195"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06250"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032423">
        <property type="entry name" value="AAA_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021886">
        <property type="entry name" value="MgsA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16193">
        <property type="entry name" value="AAA_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12002">
        <property type="entry name" value="MgsA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="62"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY70123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="472" mass="50458" checksum="D6FA825A28E10D39" modified="2017-04-12" version="1">MSYDLFGTPDPAPPTRGGSLSDATNPQAPLAVRLRPRTLDEIVGQQHLLAPGSPLRRLADGQPMSVFLWGPPGVGKTTIASVVSQATQRRFVELSAVTAGVKEVRAELEEARRELARGQATVLFVDEVHRFSKAQQDVLLPAVENRLVTLIAATTENPSFSVISPLLSRSLLLRLVPLTDEDLGGLLDRALTDDRGLINADGQRFTLDAQARDLIVRLAGGDARRALTYLEESAAAAESLGATAIDQAAVESSADRAAVRYDKDGDQHYDVISAFIKSIRGSDVDAALHYLARMLEAGEDPRFIARRLMISASEDIGMAASGVLQTCVAAAQAVQLLGMPEARLTLAHATVAAATAPKSNAAYLAITDAVADVRRGKGGLVPAHLRDAHYSGAQALGHGEGYKYAHDYPHGVAQQTYLPDDLTDARYYRPTDHGQEAAIADRVAVLRRLLGREPSARVAPSKSTEGPTHDPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEF6</accession>
    <name>A0A1Q2CEF6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Imidazole glycerol phosphate synthase subunit HisH</fullName>
            <ecNumber evidence="8">4.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">IGP synthase glutaminase subunit</fullName>
            <ecNumber evidence="8">3.5.1.2</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">IGP synthase subunit HisH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">ImGP synthase subunit HisH</fullName>
            <shortName evidence="8">IGPS subunit HisH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hisH</name>
        <name evidence="11" type="ORF">RPIT_06365</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer of HisH and HisF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="8"/>
    <dbReference type="EC" id="3.5.1.2" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06365"/>
    <dbReference type="EnsemblBacteria" id="AQP44481">
        <property type="protein sequence ID" value="AQP44481"/>
        <property type="gene ID" value="RPIT_06365"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06365"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01748">
        <property type="entry name" value="GATase1_IGP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00278">
        <property type="entry name" value="HisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010139">
        <property type="entry name" value="Imidazole-glycPsynth_HisH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42701">
        <property type="entry name" value="PTHR42701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000495">
        <property type="entry name" value="Amidotransf_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01855">
        <property type="entry name" value="IMP_synth_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6 8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GATase" evidence="10">
        <location>
            <begin position="6"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8 9">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 9">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 9">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000495-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="202" mass="21232" checksum="1F393415AF14EEF6" modified="2017-04-12" version="1">MRRVGLLDYGSGNLHSAARALSVAGADVTVSSDLAELRTLDGLVVPGVGAFAACMDSLSRSGGADLIREWAAAERPLLGICVGHQVLFDQGHEHGLVTPGIGLYEGAVVALEARRLPHMGWNTVDPGDTEILFEGLHGERFYFVHSYAAPGPVTAVRAATAEHEGSRFVAAAQRGTVSSTQFHPEKSGAAGARLIANWLRGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEH9</accession>
    <name>A0A1Q2CEH9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">tRNA/rRNA methyltransferase/putative endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06640</name>
        <name evidence="3" type="ORF">SAMN05428934_110119</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ10398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06640"/>
    <dbReference type="EnsemblBacteria" id="AQP44529">
        <property type="protein sequence ID" value="AQP44529"/>
        <property type="gene ID" value="RPIT_06640"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ10398">
        <property type="protein sequence ID" value="SDZ10398"/>
        <property type="gene ID" value="SAMN05428934_110119"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06640"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ10398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="94" mass="11097" checksum="4A8F2FD285AD8553" modified="2017-04-12" version="1">MPHMYILECADGSYYVGSTFDLGARIEQHWNGSAHSYTQRRRPFRLVYAEEFDSVVEAFDAEMKVKRWSRAKKLALIEGRWEDLRQLSKKPKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEP9</accession>
    <name>A0A1Q2CEP9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06950</name>
        <name evidence="3" type="ORF">SAMN05428934_11055</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44583">
        <property type="protein sequence ID" value="AQP44583"/>
        <property type="gene ID" value="RPIT_06950"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09183">
        <property type="protein sequence ID" value="SDZ09183"/>
        <property type="gene ID" value="SAMN05428934_11055"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06950"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012332">
        <property type="entry name" value="Autotransporter_pectin_lyase_C"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544453" evidence="1">
        <location>
            <begin position="28"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ09183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="333" mass="34763" checksum="10990BF34A666E24" modified="2017-04-12" version="1">MKRILTAAACAALAVSGLALGAPTAAADVTCRGTLTGYVGDTVEVPSGATCTLNNATVDGDVKVYRDASVTITGGRIEGNVQAESARSVVVSGTRVDGDIQPKYTTSTVNVTGTTVGGNIQVEEGRATVTLANNSVTGDVQLFKNPAGAKSVTANQIGGNLQCKENVPAPTGSGNTVRGSAEDQCRGLTGSGGGGGVDIYGTPGTHYVNGRVWNTTCEPYSQTERCRTNIQATVVEYRDGRFVKTNGWAFNNLTYLASPRALWSDNPLGAYGRVGGTARWTGSDGRAWRTECDTALTGQGGCRSFAAARVVEQTRTGYRFVTKEIFNNMVRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEX6</accession>
    <name>A0A1Q2CEX6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-oxoacyl-[acyl-carrier protein] reductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07160</name>
        <name evidence="2" type="ORF">SAMN05428934_11012</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07160"/>
    <dbReference type="EnsemblBacteria" id="AQP44620">
        <property type="protein sequence ID" value="AQP44620"/>
        <property type="gene ID" value="RPIT_07160"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08218">
        <property type="protein sequence ID" value="SDZ08218"/>
        <property type="gene ID" value="SAMN05428934_11012"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07160"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ08218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="259" mass="27256" checksum="7901871FE161E3E1" modified="2017-04-12" version="1">METDTTVARTVLVTGVGRKRGIGAGIALHLAQEGWDLALSFLPEYDDRVGLERGPRDPEDVAELCRGEGARVDLLPANLADPQVPAQLVAAANTRGDLAALVLCHTESVDSSILTTSVESWDRHYSVNARASWLLIKAFAELIPPHVREAQAGRVVALTSDHTAHNLPYGSSKGALDRIVVAAAIELAGHGISANALNPGPIDTGWMDDDVRASLTGQTPARRLGTPQDTADLVGFLLSPAGGWITGQVLHSNGGFAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEX7</accession>
    <name>A0A1Q2CEX7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribonuclease Y</fullName>
            <shortName evidence="5">RNase Y</shortName>
            <ecNumber evidence="5">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rny</name>
        <name evidence="8" type="ORF">RPIT_07075</name>
        <name evidence="9" type="ORF">SAMN05428934_11029</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Endoribonuclease that initiates mRNA decay.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RNase Y family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08588.1"/>
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        <property type="gene ID" value="RPIT_07075"/>
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        <property type="gene ID" value="SAMN05428934_11029"/>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <location>
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            <dbReference type="EMBL" id="AQP44605.1"/>
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            <dbReference type="EMBL" id="SDZ08588.1"/>
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    <sequence length="535" mass="59422" checksum="A3DE2B8BB47D364F" modified="2017-04-12" version="1"> </sequence>
</entry>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="72" mass="7901" checksum="F0EFAA3B7E5818E0" modified="2017-04-12" version="1">MVGFEDFVATGLMGGGTSEWDLAEIVEITSPEEFERDNSEMPGKEIADTWNDWVASSSVLYLTDLAEPLSRG</sequence>
</entry>
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            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="486" mass="52950" checksum="332EC07AA76D1D6C" modified="2017-04-12" version="1">MRDAAALAKSNQEQAVAAWVNHLNQLRLDNLLSAFGRQDLNLHDALASIDEAIKKIDFEVVAANRGGVKGMHGFIAEVAEVGVGNARSQILGEDAVYQWVNDNGPVDLIRGGVEIQQKFVLAGGRLGLGAIAEHLERYPDFVKNGGTYQIPRDHFEVIQKLHAMPPEEARKFLTRSGDGPSLRGWERVQDFFGQGSMGIDSLEPSHLDYNQVQKGTYNSTLEAEKESLRTTDQSRRNDAYQESRPTLQEAAKATVVAAAIEGGTAFVMAVVEKRRQGKKLKEFTSEDWTDIAGETGFGFAKGGVRGLSIYTLTNFTATSAAVASSIVTAGFGIAEQANKLRRGEIDELEFIDNAELVALEAAVSALSSFVGQALIPVPVLGAVIGNTVGTIMYKTVSTSLSQREAELIERYLDEQRVLDERLASEYQELIEMLDASMADFLDLLDRAFSPDVEIALRGSVELASELGVATEEILDSDEKTLAYFLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF12</accession>
    <name>A0A1Q2CF12_9ACTN</name>
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    </protein>
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        <name evidence="2" type="ORF">SAMN05428934_11815</name>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000018">
        <property type="protein sequence ID" value="SDZ21490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44712">
        <property type="protein sequence ID" value="AQP44712"/>
        <property type="gene ID" value="RPIT_07750"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ21490">
        <property type="protein sequence ID" value="SDZ21490"/>
        <property type="gene ID" value="SAMN05428934_11815"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07750"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ21490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="94" mass="10575" checksum="C541CE15E4E45FF8" modified="2017-04-12" version="1">MVEEPQAMASVLAELEALLRPTEPRWAHAMARYRARLEGGEPVSDVARDVVTLYSAGMGGWNDVVLQDARGVLTEQREFHRLRTELFHVARDAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF53</accession>
    <name>A0A1Q2CF53_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Acetolactate synthase</fullName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_07970</name>
        <name evidence="13" type="ORF">SAMN05428934_11334</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25249"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="2.2.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="8">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the TPP enzyme family.</text>
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    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="AQP44749">
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        <property type="gene ID" value="RPIT_07970"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16643">
        <property type="protein sequence ID" value="SDZ16643"/>
        <property type="gene ID" value="SAMN05428934_11334"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07970"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
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        <property type="entry name" value="TPP_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012846">
        <property type="entry name" value="Acetolactate_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039368">
        <property type="entry name" value="AHAS_TPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000399">
        <property type="entry name" value="TPP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00118">
        <property type="entry name" value="acolac_lg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00187">
        <property type="entry name" value="TPP_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="11">
        <location>
            <begin position="9"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="9">
        <location>
            <begin position="198"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="10">
        <location>
            <begin position="393"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP44749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDZ16643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="580" mass="62547" checksum="8478CF68D9936D9C" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF64</accession>
    <name>A0A1Q2CF64_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_08025</name>
        <name evidence="9" type="ORF">SAMN05428934_11346</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08025"/>
    <dbReference type="EnsemblBacteria" id="AQP44759">
        <property type="protein sequence ID" value="AQP44759"/>
        <property type="gene ID" value="RPIT_08025"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16888">
        <property type="protein sequence ID" value="SDZ16888"/>
        <property type="gene ID" value="SAMN05428934_11346"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08025"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0697">Rotamase</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544451" description="Peptidylprolyl isomerase" evidence="6">
        <location>
            <begin position="28"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="130"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="272"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="38"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="40"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ16888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="363" mass="37112" checksum="64CE4B5A3FEF6BDB" modified="2017-04-12" version="1">MRAVGQVGYHARVTFSLSRVALATAAAALITLTACGGGDNEATPETTTPTATASASVSGSPSASASPSESVSPSAEASPTVSVTPSDDLSAIEVSEGDVPEITVPAPWAISETTTEVLTPGTSEQTLTDTSTVTINYLGVNGRTGEVFDGSYEGGQPAVFPLDQVIPGFQKGLSGQQVGSRVLIGMPAEDGYPDGTGDGRIEPGDSLLFVVDIISANFEEATGEEVPPVEGLPTVTMADDGPSIQIPAGVAAPTELQAQPLIKGTGAAVTAESTIQVRYRSWVYDGGELLEDAWRPQAGQLSQLIQGWQQGLVGQTAGSRVLLVVPPALAFPDGRPEATPALEAGQTLVYVIDLLDVQNPPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFA1</accession>
    <name>A0A1Q2CFA1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Arginine biosynthesis bifunctional protein ArgJ</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="7">Glutamate N-acetyltransferase</fullName>
                <ecNumber evidence="7">2.3.1.35</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="7">Ornithine acetyltransferase</fullName>
                <shortName evidence="7">OATase</shortName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="7">Ornithine transacetylase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="7">Amino-acid acetyltransferase</fullName>
                <ecNumber evidence="7">2.3.1.1</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="7">N-acetylglutamate synthase</fullName>
                <shortName evidence="7">AGSase</shortName>
            </alternativeName>
        </domain>
        <component>
            <recommendedName>
                <fullName evidence="7">Arginine biosynthesis bifunctional protein ArgJ alpha chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="7">Arginine biosynthesis bifunctional protein ArgJ beta chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="7" type="primary">argJ</name>
        <name evidence="8" type="ORF">RPIT_08215</name>
        <name evidence="9" type="ORF">SAMN05428934_11532</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate + N(2)-acetyl-L-ornithine = L-ornithine + N-acetyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:15349"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
            <dbReference type="EC" id="2.3.1.35"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N(2)-acetyl-L-ornithine (cyclic): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Heterotetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ArgJ family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.35" evidence="7"/>
    <dbReference type="EC" id="2.3.1.1" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08215"/>
    <dbReference type="EnsemblBacteria" id="AQP44783">
        <property type="protein sequence ID" value="AQP44783"/>
        <property type="gene ID" value="RPIT_08215"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19659">
        <property type="protein sequence ID" value="SDZ19659"/>
        <property type="gene ID" value="SAMN05428934_11532"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08215"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00106"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004042">
        <property type="term" value="F:acetyl-CoA:L-glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004358">
        <property type="term" value="F:glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103045">
        <property type="term" value="F:methione N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02152">
        <property type="entry name" value="OAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01106">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002813">
        <property type="entry name" value="Arg_biosynth_ArgJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016117">
        <property type="entry name" value="ArgJ-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042195">
        <property type="entry name" value="ArgJ_beta_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23100">
        <property type="entry name" value="PTHR23100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01960">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56266">
        <property type="entry name" value="SSF56266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00120">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_5034869845" description="Arginine biosynthesis bifunctional protein ArgJ alpha chain" evidence="7">
        <location>
            <begin position="1"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5034869846" description="Arginine biosynthesis bifunctional protein ArgJ beta chain" evidence="7">
        <location>
            <begin position="183"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="382"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="387"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="7">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="7">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="7">
        <location>
            <begin position="182"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ19659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="387" mass="39458" checksum="9779FDEFB31225EA" modified="2017-04-12" version="1">MTERSGVTLPAGFVASGVTAGLKSSGKPDVALVVNEGPRMAAAAVFTSNRVFAAPVKWSRQAVADGQLQAVVLNSGGANACTGPEGFADSAATASRVADNLGLITDNVAVCSTGLIGIRLPMDRLLGGVDAASNALSPDGGALAAEAIMTTDSVPKQAGSSGDGWAIGGMAKGAGMLAPGLATMLVVLTTDADLAAEELDTALREATRVSFDRADADGCMSTNDTVILMASGASGQSPTPDEFTQSLTLVCQDLARQLIADAEGAHHEIAIDVVGAASERDAEVVGREIARSNLFKCAIFGGDPNWGRVLSAIGVTDAKFDPDALDVSFNSVMVCRGGQIGEDRSLVDLSGRSVTVTVDLHAGDSTATILTNDLTYDYVRENAEYST</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFA7</accession>
    <name>A0A1Q2CFA7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07975</name>
        <name evidence="3" type="ORF">SAMN05428934_11335</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07975"/>
    <dbReference type="EnsemblBacteria" id="AQP44750">
        <property type="protein sequence ID" value="AQP44750"/>
        <property type="gene ID" value="RPIT_07975"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16665">
        <property type="protein sequence ID" value="SDZ16665"/>
        <property type="gene ID" value="SAMN05428934_11335"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07975"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ16665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="165" mass="17081" checksum="E6ABF1A37522CF23" modified="2017-04-12" version="1">MKATKIVGIVSIIAGLIMIVAGAITWGVVTSQLKAENITVPGDSEFMGGAYAGEKVGGPLSAYAQADIINVHALEGSGGETYATLGTLANEAREAGDEAKAEEYQAQRATMMNASFLRSSLFSSVIAYGVSALVMGLGLILGLIGWALTTIRNREYVADGAAVRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFD9</accession>
    <name>A0A1Q2CFD9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Arginine repressor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">argR</name>
        <name evidence="12" type="ORF">RPIT_08200</name>
        <name evidence="13" type="ORF">SAMN05428934_11535</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Regulates arginine biosynthesis genes.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid biosynthesis; L-arginine biosynthesis [regulation].</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the ArgR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08200"/>
    <dbReference type="EnsemblBacteria" id="AQP44780">
        <property type="protein sequence ID" value="AQP44780"/>
        <property type="gene ID" value="RPIT_08200"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19731">
        <property type="protein sequence ID" value="SDZ19731"/>
        <property type="gene ID" value="SAMN05428934_11535"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08200"/>
    <dbReference type="UniPathway" id="UPA00068"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034618">
        <property type="term" value="F:arginine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051259">
        <property type="term" value="P:protein complex oligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00173">
        <property type="entry name" value="Arg_repressor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001669">
        <property type="entry name" value="Arg_repress"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020899">
        <property type="entry name" value="Arg_repress_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036251">
        <property type="entry name" value="Arg_repress_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020900">
        <property type="entry name" value="Arg_repress_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34471">
        <property type="entry name" value="PTHR34471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01316">
        <property type="entry name" value="Arg_repressor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02863">
        <property type="entry name" value="Arg_repressor_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01467">
        <property type="entry name" value="ARGREPRESSOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55252">
        <property type="entry name" value="SSF55252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="5 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0678">Repressor</keyword>
    <keyword evidence="8 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Arg_repressor" evidence="10">
        <location>
            <begin position="7"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="Arg_repressor_C" evidence="11">
        <location>
            <begin position="87"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP44780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDZ19731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="165" mass="17310" checksum="EF47DA116F87ED32" modified="2017-04-12" version="1">MHMSEVSRAGRHATLRRLLVEARFASQAELIEALAGEGITVSQPTLSKDLLELGAVRERSADGVLVYAAPQGDAGGAALDKLARLCSELLQSIRHAGTQILVRTPPGAAQYFASYLDLASLRGVLGTIAGDDTVLVIAIDEQSAESLVGAISEMTKTGRPAKELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFP2</accession>
    <name>A0A1Q2CFP2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09180"/>
    <dbReference type="EnsemblBacteria" id="AQP44936">
        <property type="protein sequence ID" value="AQP44936"/>
        <property type="gene ID" value="RPIT_09180"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09180"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="194" mass="21489" checksum="C1F94FC6BC903CF0" modified="2017-04-12" version="1">MRFLDETTLQDAFVRLEPLDHAHADELSRAAATLTPAWYTSVPTADEVPAEIDRRLALREAGAMNPFAVRRLHTGEVVGMTTFCTIDQPNRRVEIGYTWIGAPAQGTEVNPAMKRLLLGHAFDACDAIAVALMTHFHNRQSRAAIERLGAKLDGILRSHRIMPDGSLRDTAAYSILPHEWPAVRSGLDARLAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFU7</accession>
    <name>A0A1Q2CFU7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Glutamate racemase</fullName>
            <ecNumber evidence="2 7">5.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">murI</name>
        <name evidence="8" type="ORF">RPIT_09505</name>
        <name evidence="9" type="ORF">SAMN05428934_102405</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Provides the (R)-glutamate required for cell wall biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate = D-glutamate</text>
            <dbReference type="Rhea" id="RHEA:12813"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29986"/>
            <dbReference type="EC" id="5.1.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the aspartate/glutamate racemases family.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.3" evidence="2 7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY59882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09505"/>
    <dbReference type="EnsemblBacteria" id="AQP44991">
        <property type="protein sequence ID" value="AQP44991"/>
        <property type="gene ID" value="RPIT_09505"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59882">
        <property type="protein sequence ID" value="SDY59882"/>
        <property type="gene ID" value="SAMN05428934_102405"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09505"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008881">
        <property type="term" value="F:glutamate racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00258">
        <property type="entry name" value="Glu_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001920">
        <property type="entry name" value="Asp/Glu_race"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018187">
        <property type="entry name" value="Asp/Glu_racemase_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033134">
        <property type="entry name" value="Asp/Glu_racemase_AS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004391">
        <property type="entry name" value="Glu_race"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21198:SF2">
        <property type="entry name" value="PTHR21198:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53681">
        <property type="entry name" value="SSF53681"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00067">
        <property type="entry name" value="glut_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00923">
        <property type="entry name" value="ASP_GLU_RACEMASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00924">
        <property type="entry name" value="ASP_GLU_RACEMASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="14"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="46"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="78"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="188"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY59882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="279" mass="29704" checksum="13E95D98398BA88D" modified="2017-04-12" version="1">MTVSDIDRPIGVFDSGFGGLTVLRSLVEQLPNEDFIYLGDTARAPYGPRAIAEVRRFALQGLDYLVAQGVKALVIACNSASAAVLRDARERYEVPITEVVLPAASRAVAATRNRRVGVVATQSTVNSAAYEDAFAIAPHITLTSKACPRFVEFVEAGITGGDELLAVAEEYLEPVKRAQADTLILGCTHYPLLSGVIGYVLGNGVTLVSSAEACAQATYTTLTQAGLLRHQPREAKREFLTTGDARDFQGIGRRLLGGFVSNATTVVIDKEAGHGPDHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG03</accession>
    <name>A0A1Q2CG03_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Phosphomannomutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_09710</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
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    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="A-D-PHexomutase_C"/>
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    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
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        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
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        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="8">
        <location>
            <begin position="56"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="9">
        <location>
            <begin position="216"/>
            <end position="314"/>
        </location>
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        <location>
            <begin position="325"/>
            <end position="435"/>
        </location>
    </feature>
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        <location>
            <begin position="447"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP45027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="553" mass="58165" checksum="1B5C0370BFF7B0B7" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG05</accession>
    <name>A0A1Q2CG05_9ACTN</name>
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        <submittedName>
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        </submittedName>
        <submittedName>
            <fullName evidence="9">Cation/acetate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_09815</name>
        <name evidence="9" type="ORF">SAMN05428934_102343</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    </organism>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY58172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09815"/>
    <dbReference type="EnsemblBacteria" id="AQP45046">
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        <property type="gene ID" value="RPIT_09815"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY58172">
        <property type="protein sequence ID" value="SDY58172"/>
        <property type="gene ID" value="SAMN05428934_102343"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09815"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="486"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY58172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="535" mass="55773" checksum="36732816497C7476" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG24</accession>
    <name>A0A1Q2CG24_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phage shock protein C (PspC) family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_09920</name>
        <name evidence="9" type="ORF">SAMN05428934_102322</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY57503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45066">
        <property type="protein sequence ID" value="AQP45066"/>
        <property type="gene ID" value="RPIT_09920"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57503">
        <property type="protein sequence ID" value="SDY57503"/>
        <property type="gene ID" value="SAMN05428934_102322"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09920"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007168">
        <property type="entry name" value="Phageshock_PspC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04024">
        <property type="entry name" value="PspC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="PspC" evidence="7">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY57503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="90" mass="9573" checksum="AFA059FBC70A4AB6" modified="2017-04-12" version="1">MKLTRSNDGMIGGVAAGLAKAFNIDATIVRLAFVLVTVLGGSGVLIYVALWVILPREDTGGTIAEEQFRKARSWYDGRRGGPGGSNDYTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG73</accession>
    <name>A0A1Q2CG73_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09890"/>
    <dbReference type="EnsemblBacteria" id="AQP45060">
        <property type="protein sequence ID" value="AQP45060"/>
        <property type="gene ID" value="RPIT_09890"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09890"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="116" mass="12636" checksum="2023A638DD4918D6" modified="2017-04-12" version="1">MEFLFNLALLFHFIGFAALFGGAFVQAKGPRRIINPAMFHGALTMLVTGLLLVGVWEMGSFRDGDPNHLKIGIKFLVLVGVFVFVLVNRKKDNVPAGQFWAIAGLTALNAAIAVFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG93</accession>
    <name>A0A1Q2CG93_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09915</name>
        <name evidence="3" type="ORF">SAMN05428934_102323</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY57530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45065">
        <property type="protein sequence ID" value="AQP45065"/>
        <property type="gene ID" value="RPIT_09915"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57530">
        <property type="protein sequence ID" value="SDY57530"/>
        <property type="gene ID" value="SAMN05428934_102323"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09915"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY57530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="60" mass="6143" checksum="66C0C0DE77EE4564" modified="2017-04-12" version="1">MRRHDVAAIAVGLAAVGFALVLLLVDRLSPSAVQPALAIALAVAGAVALLFSFIRHSPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGE1</accession>
    <name>A0A1Q2CGE1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Iron complex transport system substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_10470</name>
        <name evidence="4" type="ORF">SAMN05428934_102211</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY54476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10470"/>
    <dbReference type="EnsemblBacteria" id="AQP45167">
        <property type="protein sequence ID" value="AQP45167"/>
        <property type="gene ID" value="RPIT_10470"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY54476">
        <property type="protein sequence ID" value="SDY54476"/>
        <property type="gene ID" value="SAMN05428934_102211"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10470"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01140">
        <property type="entry name" value="FatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033870">
        <property type="entry name" value="FatB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544476" evidence="1">
        <location>
            <begin position="23"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="2">
        <location>
            <begin position="56"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY54476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="315" mass="33180" checksum="D2764BC4458B0187" modified="2017-04-12" version="1">MNISKRLMAAAAASLLALTACGADSTDNTPADAPSAESITIEHTQGTTTLDGPAQTIVALDLGALDTLNALGVADRVVGIPEVAAMPEALADFSDVETVGTMQEPNLEKIAELNPDLVIAGFRSAKLTPELAKNFNVIDVTYGSDESFYDGVAYASTLIGQAVGLEDETDEQLAELRETIDDAKAKVNPEHKALIVMTTGGKAGAHGAESRYGVVHKDLGIKPALDNIKTESHGDPISFEAIQQANPDLLIVVDRDAAVGQEGAAAEQVLDNELVASTNAWKNDQVVYLDGGRWYLMIHGLDNSVEMINEIAEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGE7</accession>
    <name>A0A1Q2CGE7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10575</name>
        <name evidence="3" type="ORF">SAMN05428934_102190</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY53796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45186">
        <property type="protein sequence ID" value="AQP45186"/>
        <property type="gene ID" value="RPIT_10575"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY53796">
        <property type="protein sequence ID" value="SDY53796"/>
        <property type="gene ID" value="SAMN05428934_102190"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10575"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018658">
        <property type="entry name" value="DUF2089"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09862">
        <property type="entry name" value="DUF2089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY53796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="138" mass="14992" checksum="456517C055D91D2E" modified="2017-04-12" version="1">MVKHLYHAPADCPVCGDELITTRKGCLKCGSELAGEFASCEFCALSEPDLQILRVFLGSRGNLREVEKHLQVSYPTARARLDAVLVKLGFDQAGERNAPEHAEQDGRDSDSATPESQILERVARGELSPEVAAQLLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGH3</accession>
    <name>A0A1Q2CGH3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitronate monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10685</name>
        <name evidence="3" type="ORF">SAMN05428934_102168</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="gene ID" value="SAMN05428934_102168"/>
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    </dbReference>
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    </dbReference>
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        <location>
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            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="AQP45203.1"/>
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        <source>
            <dbReference type="EMBL" id="SDY53169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="335" mass="35393" checksum="3ECD9A1A15AA35DA" modified="2017-04-12" version="1">MSLPILQAPMAGVQGVALALAVGRAGGIGSLPAAMMSSEPLVASLRQLDAAKAAYNVNFFAHTPREPDERLQRWADSLAAYREEFGVREVASMGSERRPFGEEALAAVTTASPTIVSFHFGLPAKPLLAELKRRLPDTFIASTATTVDEARWLEENGAQMVVAQGWEAGGHRGHFLSDDLSLHLPTRELVAAIRAAVRLPVIAAGGITTPAQVRAALAAGASAVQCGTAFLLADEAATPDLHRTAIEQPHETVVTTVMTGRPARGIPNRLIRDLGETPDDLPGYPHTAGPLAPLRAAAEARGRTDFTPLWCGANTDSVRRGAAEDIVARLMGEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGL0</accession>
    <name>A0A1Q2CGL0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Assimilatory sulfite reductase (ferredoxin)</fullName>
            <ecNumber evidence="5">1.8.7.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
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        <name evidence="19" type="ORF">SAMN05428934_102126</name>
    </gene>
    <organism evidence="18 20">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="18 20" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">RP1T</strain>
        </source>
    </reference>
    <reference evidence="19 21" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 21">RP1</strain>
        </source>
    </reference>
    <reference evidence="18" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3 H2O + hydrogen sulfide + 6 oxidized [2Fe-2S]-[ferredoxin] = 7 H(+) + 6 reduced [2Fe-2S]-[ferredoxin] + sulfite</text>
            <dbReference type="Rhea" id="RHEA:23132"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="EC" id="1.8.7.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Nitrogen metabolism; nitrate reduction (assimilation).</text>
    </comment>
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    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY51828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10890"/>
    <dbReference type="EnsemblBacteria" id="AQP45237">
        <property type="protein sequence ID" value="AQP45237"/>
        <property type="gene ID" value="RPIT_10890"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY51828">
        <property type="protein sequence ID" value="SDY51828"/>
        <property type="gene ID" value="SAMN05428934_102126"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10890"/>
    <dbReference type="UniPathway" id="UPA00653"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="UniProtKB-EC"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
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    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Nitri_red_NirB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017121">
        <property type="entry name" value="Nitrite_Rdtase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041575">
        <property type="entry name" value="Rubredoxin_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04324">
        <property type="entry name" value="Fer2_BFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18267">
        <property type="entry name" value="Rubredoxin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037149">
        <property type="entry name" value="NirB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00397">
        <property type="entry name" value="SIROHAEM"/>
    </dbReference>
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        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02374">
        <property type="entry name" value="nitri_red_nirB"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 12" id="KW-0274">FAD</keyword>
    <keyword evidence="7 12" id="KW-0285">Flavoprotein</keyword>
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    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 12" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0883">Thioether bond</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="16">
        <location>
            <begin position="5"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Rubredoxin_C" evidence="17">
        <location>
            <begin position="325"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Fer2_BFD" evidence="15">
        <location>
            <begin position="424"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR_ferr" evidence="14">
        <location>
            <begin position="561"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="13">
        <location>
            <begin position="633"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRNR" id="PIRNR037149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03460"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF04324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF18267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="AQP45237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="SDY51828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="866" mass="92122" checksum="F2E2B292BF0C23DE" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGN0</accession>
    <name>A0A1Q2CGN0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphoserine transaminase</fullName>
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        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Phosphohydroxythreonine aminotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_11125</name>
        <name evidence="11" type="ORF">SAMN05428934_10279</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16573"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58452"/>
            <dbReference type="ChEBI" id="CHEBI:58538"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:14329"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57524"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.52" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY50388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11125"/>
    <dbReference type="EnsemblBacteria" id="AQP45278">
        <property type="protein sequence ID" value="AQP45278"/>
        <property type="gene ID" value="RPIT_11125"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY50388">
        <property type="protein sequence ID" value="SDY50388"/>
        <property type="gene ID" value="SAMN05428934_10279"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11125"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00197"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004648">
        <property type="term" value="F:O-phospho-L-serine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022278">
        <property type="entry name" value="Pser_aminoTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006272">
        <property type="entry name" value="Pser_aminoTfrase_mycobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000525">
        <property type="entry name" value="SerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01366">
        <property type="entry name" value="serC_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0718">Serine biosynthesis</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="9">
        <location>
            <begin position="135"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP45278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY50388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="366" mass="39075" checksum="15F1F0E398E2862E" modified="2017-04-12" version="1">MIQLPEDLLPVDGRFGSGPAKVRPEALEYLSLRGDIMGTSHRQAPVRNLVASVQESLAELYSIPDGYEVVLGNGGSTVFWDVAVSSLIERRSAHGVFGEFSRKFYAAAARAPHLENPAISEAPAGSVALPEPTDADVYAWAQNETSTGAAAPVRRIGDGLVLVDATSAAGGMPADISATDVYYFAPQKNFSSDGGLWLAFLSPAAVERAESIKASGRWIPESLDLTVAIRNSRQHQTLNTPALATLLLLEDQLGWMLELGGLSVVADRCAESTTILYDWAEGSEFATPFVANPAERSPVVATIDLADEVDGKQLIAELRANGIVDVDPYRALGRNQLRVGCYASVDPEDVVALTECVDYLVARMIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGS0</accession>
    <name>A0A1Q2CGS0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Methylmalonyl-CoA carboxyltransferase 1.3S subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_11355</name>
        <name evidence="4" type="ORF">SAMN05428934_10232</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY48976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11355"/>
    <dbReference type="EnsemblBacteria" id="AQP45318">
        <property type="protein sequence ID" value="AQP45318"/>
        <property type="gene ID" value="RPIT_11355"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY48976">
        <property type="protein sequence ID" value="SDY48976"/>
        <property type="gene ID" value="SAMN05428934_10232"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11355"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0092">Biotin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="2">
        <location>
            <begin position="45"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY48976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="119" mass="12094" checksum="A369AD04C0E54B05" modified="2017-04-12" version="1">MKLKVTVNQTEYEIDVEVEEEQPQGLGPIVIGVNAGSNPIPTKASVSAVSSNAVVAPLAGSVARILVSEGDEIEAGQVLLVLEAMKMETEITAPAAGTVAAILVGPGEAVQGGQALIEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGV9</accession>
    <name>A0A1Q2CGV9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyltransferase (GNAT) domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11190</name>
        <name evidence="3" type="ORF">SAMN05428934_10266</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY50008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11190"/>
    <dbReference type="EnsemblBacteria" id="AQP45290">
        <property type="protein sequence ID" value="AQP45290"/>
        <property type="gene ID" value="RPIT_11190"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY50008">
        <property type="protein sequence ID" value="SDY50008"/>
        <property type="gene ID" value="SAMN05428934_10266"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11190"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="27"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY50008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="175" mass="19513" checksum="4E16159F9BCF3191" modified="2017-04-12" version="1">MQKPLIAAPEPADAGAWFDFLIEQQTVTYQGIVRPDFAEVQSQYRDEWVPDLARQFADPGTAKFAVAKDGEKIVGLASAVDGPQQWEVQYGLTPSPADRELARLYVSPEFQGTGLALDLFRAVDDGQDLYLWLISGNARAERFYVRRGFVSLDESFRSGPSWGGAPMHRMVRRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGZ3</accession>
    <name>A0A1Q2CGZ3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Carbohydrate ABC transporter membrane protein 2, CUT1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_11670</name>
        <name evidence="7" type="ORF">SAMN05428934_106141</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11670"/>
    <dbReference type="EnsemblBacteria" id="AQP45374">
        <property type="protein sequence ID" value="AQP45374"/>
        <property type="gene ID" value="RPIT_11670"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93764">
        <property type="protein sequence ID" value="SDY93764"/>
        <property type="gene ID" value="SAMN05428934_106141"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11670"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="231"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="65"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY93764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="270" mass="29669" checksum="BFF3AB245715260C" modified="2017-04-12" version="1">MQLARKLILIVLGIIWLIPIYLMVINAAKLSSDYGNATVWIPTDLSGLLQNFADALDRGRIARGLTSTFIYSIVSPLIAVIVGAMAGFAIVALKVKRAFMWFVLIFSATVFPIQMVLMPLFIGYVEVGIFDSRLGMILIYTVISVPFSAFVLRNFFSGIAHQVYEAAALDGASAFQTFFRIYLPMSKSALFAVFILQATFIWNDLLLGLSLSQDQDVRPVMTTLAAMQTTYGGSTMPVVLAGGLLVSLPTIVLFLFTQRYFTQGLALGQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH40</accession>
    <name>A0A1Q2CH40_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aamy domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_11940</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11940"/>
    <dbReference type="EnsemblBacteria" id="AQP45421">
        <property type="protein sequence ID" value="AQP45421"/>
        <property type="gene ID" value="RPIT_11940"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11940"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051060">
        <property type="term" value="F:pullulanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011839">
        <property type="entry name" value="Pullul_strch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024561">
        <property type="entry name" value="Pullul_strch_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040671">
        <property type="entry name" value="Pullulanase_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045041">
        <property type="entry name" value="Pullulanase_PULA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43631">
        <property type="entry name" value="PTHR43631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11852">
        <property type="entry name" value="DUF3372"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17967">
        <property type="entry name" value="Pullulanase_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02103">
        <property type="entry name" value="pullul_strch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="3">
        <location>
            <begin position="100"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1272"/>
            <end position="1291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="2074" mass="222723" checksum="2F7DA43FE97A6F55" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH43</accession>
    <name>A0A1Q2CH43_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent dehydratase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Putative NADH-flavin reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_11830</name>
        <name evidence="3" type="ORF">SAMN05428934_106109</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11830"/>
    <dbReference type="EnsemblBacteria" id="AQP45403">
        <property type="protein sequence ID" value="AQP45403"/>
        <property type="gene ID" value="RPIT_11830"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93066">
        <property type="protein sequence ID" value="SDY93066"/>
        <property type="gene ID" value="SAMN05428934_106109"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11830"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="7"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY93066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="235" mass="24841" checksum="A31E6FBDFACED004" modified="2017-04-12" version="1">MKITIIGGHGKIALLTAAMLSESGHQVRSVVRNEDHRSDVEETGAHCVVADVETLDTDALGEVLDGSEAVVWSAGAGGGNPERTYAVDRDAAIRSIDAAAARGIPRFIMVSYVGSGRDEVPQDNPFHHYAVAKAAADDHLRSSPLQWTILAPGQLTEEEATRKFDVGDHVTHGATSRANVAHLIAAVLPRMSTAGLTLRFRDGAVALEDVLVSLERVAAGSPVAPLREGRTDLVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH61</accession>
    <name>A0A1Q2CH61_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proton-translocating NAD(P)(+) transhydrogenase</fullName>
            <ecNumber evidence="3">7.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">RPIT_11895</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+)(in) + NAD(+) + NADPH = H(+)(out) + NADH + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:47992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="7.1.1.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="7.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11895"/>
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        <property type="gene ID" value="RPIT_11895"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11895"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:NAD(P)+ transhydrogenase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="AlaDH/PNT_N"/>
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    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="NADP_transhyd_a"/>
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        <property type="entry name" value="NADP_transhyd_a_C"/>
    </dbReference>
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        <property type="entry name" value="AlaDh_PNT_C"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PNTB_4TM"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="pntA"/>
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    </dbReference>
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    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="448"/>
            <end position="468"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
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            <end position="504"/>
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    <feature type="domain" description="AlaDh_PNT_N" evidence="12">
        <location>
            <begin position="4"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="AlaDh_PNT_C" evidence="11">
        <location>
            <begin position="144"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00003943"/>
        </source>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023027"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
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        <source>
            <dbReference type="EMBL" id="AQP45413.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="510" mass="52775" checksum="8D6B0FE26FAE7ABF" modified="2017-04-12" version="1">MEIGVPKEAADTRVAATPKTIEGLLKLGYEVLVEAGAGALAAFDDQQYADAGARVVDTAEAWGADIVLTVNAPTADQLALVRRGAILFSFLFPRQNPDVADQYAARGITALSMDMVPRTSRAQSLDALSAFANISGYRAVVEAAHAFGRFFTGQVTAAGKVPPARVLVAGTGVAGLAAIGAANSMGAVVSATDVRPETAEQVESMGATFLHVAQADQGVSSDGYAKEVGADYAARAAELYAEQAPVTDIIITTAAIPGRPSPKLITADMVDSMKNGSVIVDLAALGGGNCELTRPGEAYTTANGVTIIGWTDLASRLPGQSSQLYGTNLVNALGLMTPEKDGRAVVDFDDEVIRTMTVAHEGAVTFPPPAVQVAAVPAPAAKEVAPLPAAPPKPPRPWWHQVLAVGIGSLAMIGALTFAPPGLVGLFGIFVVAVVVGYYVVWNVTHALHTPLMSVTNAISGIIIVGAMTQLASDSWTVKILAFIAVLIASINVFGGFTVTARMLNMFRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH68</accession>
    <name>A0A1Q2CH68_9ACTN</name>
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        <submittedName>
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        </submittedName>
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        <name evidence="3" type="ORF">RPIT_11865</name>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
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            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="37"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY92905.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="154" mass="16628" checksum="D7A9C0820A2DF679" modified="2017-04-12" version="1">MARLLFLAVAVALALTGCGVPRDPDGTLERARQRGHLIVGASHSEPVLMVDGDDVSGPEAELIEQFAESQGLSVRWVPGGEEKLVGMIEHGDVDLIVGGLTAKSPWSDKVGLTRPWTEDVDDYGKPSKRVVAAPLGENALISEVERFFDARRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH86</accession>
    <name>A0A1Q2CH86_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase</fullName>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12200</name>
        <name evidence="3" type="ORF">SAMN05428934_10636</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP45471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="AQP45471"/>
        <property type="gene ID" value="RPIT_12200"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY91469"/>
        <property type="gene ID" value="SAMN05428934_10636"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0000166">
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF01408">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="4"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY91469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="332" mass="35607" checksum="B8A97A4FE209C6E8" modified="2017-04-12" version="1">MNTVRWGIVGTGAIAHGVVGDFQFVPGAELAAVASRTESKAKDFADQYGIPGAFGSYRAMLESDDVDVVYIATPHPQHRDIALAAIDNGKAVLVEKAFTATLKGTQQVVDAARAKGVFAMEAMWTRFLPVVAAAREVVAWGRIGDVVGVQGDLYAYREYQADHRLFAPELGGGAILDLGVYVVNFAQAFLGDVKEIDSRARLYPTGVDKAVTMNLVHAAGGLSSLTCGFDGHGPGRMIVVGTKGWIEVEPRFHHPSMITVHRNGVLPRIIEALPTGRGYSHEFAEVTARIAAGETESPTMPLRDTLEVMKVLDKCLHQAGITQREADVDLGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH88</accession>
    <name>A0A1Q2CH88_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbohydrate ABC transporter substrate-binding protein, CUT1 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_12220</name>
        <name evidence="4" type="ORF">SAMN05428934_10632</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY91378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12220"/>
    <dbReference type="EnsemblBacteria" id="AQP45474">
        <property type="protein sequence ID" value="AQP45474"/>
        <property type="gene ID" value="RPIT_12220"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY91378">
        <property type="protein sequence ID" value="SDY91378"/>
        <property type="gene ID" value="SAMN05428934_10632"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12220"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022386">
        <property type="entry name" value="Chitin_NgcE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03851">
        <property type="entry name" value="chitin_NgcE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544486" evidence="2">
        <location>
            <begin position="30"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY91378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="461" mass="48760" checksum="2E5F446E50F3BDBF" modified="2017-04-12" version="1">MKISRRHVLATLAASSVAAVACQPDPPEAPSGPSSPAASPSASPSALPFGLETPSRVEAVVFDGGFGTGYVRAAAGLLSDLYDGVTVLVTPTTDISGTVADLFADGATPPDLIDNSGVGKLSVASMADDFASLDDVVESENLEGIPIAETLYHGVLDAGTFNGRLIAINYALSVYGLWHSATAFAAAGWAVPATWDTLLELGEEARREGRYLFVWGEGAESYYQELAITSAIKEGGHDVRRALDNLEEGCWFHPAVSGVLDQLELCVAEGFLLDGGPYLEAQERWSRDGEALLYPSGAWIAHEMAGTASADFAFTVAPVPTLTAAPTLPATAIHSAPTEQFLVPERANNPAGGKELLRIMLSQQAAADFSRTNLIPTVVRGSVPADVESTALASQTRLLADAGEDVFTWRFDSHYGLGQETNNAWRGFLRAEYGAAVLAERLQSLTDAVRNDPDIERYTVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH95</accession>
    <name>A0A1Q2CH95_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized membrane protein YcfT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_12320</name>
        <name evidence="4" type="ORF">SAMN05428934_10612</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY90918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12320"/>
    <dbReference type="EnsemblBacteria" id="AQP45489">
        <property type="protein sequence ID" value="AQP45489"/>
        <property type="gene ID" value="RPIT_12320"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY90918">
        <property type="protein sequence ID" value="SDY90918"/>
        <property type="gene ID" value="SAMN05428934_10612"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12320"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="350"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl_transf_3" evidence="2">
        <location>
            <begin position="63"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY90918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="408" mass="45270" checksum="0CD1810F4ACA6AB4" modified="2017-04-12" version="1">MVLAAAAVVVSQFLVEPLLRLNGWTALGSLAGFLAVAVAIVAAARHLNGRQGSIPEVDARRLAWADLAKAIAVVLVVAYHVSPTTMGHLMVGTNRAAGLYASFTTWLLPVRMPLFFLISGMLSVRALHRPWRAVWRPRVADILWPFVLWTALLAVPFALAYVATDPFGYLPRQAGWLVNFAGNYWYLPLLVAFFLTARMLRGAPLFAVALGVLLYFWSGPMPRDIGGVFLNDAMLTLIRFCIFWIWFAVGAFARPLVVRWARAPWWLGLIAFVAYWPLAWLRYERGMDDLTPTATVVGITAILVFARLLARWAPAARLGSYLAARTLPIYLYHPLLLALLVLTLPKYDGVGSVVVIPLVPILVISAVAIACLAYDATRHRLPWLYRWPVRAAQREPSPAESAVPQRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHA2</accession>
    <name>A0A1Q2CHA2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_12100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45453">
        <property type="protein sequence ID" value="AQP45453"/>
        <property type="gene ID" value="RPIT_12100"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12100"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="175" mass="19288" checksum="DFB85ECFBCE8E27E" modified="2017-04-12" version="1">MQFTLHTTSASGRQEAATAGWWVARQDGLVRVDVAGGSGGQQVAAEEALEAYRRLGLADLRYDERWVLVLSAKYPGSSDPLQTAANGSNTFYFSDILTFHEDLVQRLYDVNVKMLRTADWGKQGGRDLWFTVADPGGLTSAAEAEAWCAARFPELSGEVLQNQCLPRRMRAPHHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHC1</accession>
    <name>A0A1Q2CHC1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Peptide/nickel transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_12415</name>
        <name evidence="8" type="ORF">SAMN05428934_104202</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY80606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_068752174.1">
        <property type="nucleotide sequence ID" value="NZ_CP019605.1"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12415"/>
    <dbReference type="EnsemblBacteria" id="AQP45507">
        <property type="protein sequence ID" value="AQP45507"/>
        <property type="gene ID" value="RPIT_12415"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY80606">
        <property type="protein sequence ID" value="SDY80606"/>
        <property type="gene ID" value="SAMN05428934_104202"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12415"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="97"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY80606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="321" mass="35165" checksum="AB42AD0431A52ACC" modified="2017-04-12" version="1">MSNFIRLLLRRVLAMPIMVLGATLLVFLVMSLSTADPARLALGESATPEALENYRERFNLNDPLLVKYVRYLGGLVQGDLGESFTGVPIGEMVARSFPITLQLTFIGLFLGVIIALVLGIIAALFRDKWPDQVIRFVSIASLATPSFWLALLFIQWFANIPGGLGWFPAVITNWINFSDDPAGYINQVTLPAVGMAIPLSGSLTRVVRTAMVEELDRDYVRTAIGAGIPKHIVVARNVLRNALITPLTVLGLRVGYMMGGAVVIEMIFNIQGMGNLIFQGIMRNDVNIVQGVTITIALAFIIINLVVDLLYVLVNPRIRSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHI7</accession>
    <name>A0A1Q2CHI7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nicotinate-nucleotide diphosphorylase (carboxylating)</fullName>
            <ecNumber evidence="4">2.4.2.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Quinolinate phosphoribosyltransferase [decarboxylating]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">RPIT_12795</name>
        <name evidence="14" type="ORF">SAMN05428934_104128</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the catabolism of quinolinic acid (QA).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from quinolinate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the NadC/ModD family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.19" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY78518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12795"/>
    <dbReference type="EnsemblBacteria" id="AQP45574">
        <property type="protein sequence ID" value="AQP45574"/>
        <property type="gene ID" value="RPIT_12795"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY78518">
        <property type="protein sequence ID" value="SDY78518"/>
        <property type="gene ID" value="SAMN05428934_104128"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12795"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00331"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01572">
        <property type="entry name" value="QPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004393">
        <property type="entry name" value="NadC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027277">
        <property type="entry name" value="NadC/ModD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037128">
        <property type="entry name" value="Quinolinate_PRibosylTase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022412">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179">
        <property type="entry name" value="PTHR32179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02749">
        <property type="entry name" value="QRPTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006250">
        <property type="entry name" value="NadC_ModD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00078">
        <property type="entry name" value="nadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="QRPTase_N" evidence="12">
        <location>
            <begin position="19"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="QRPTase_C" evidence="11">
        <location>
            <begin position="111"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="132"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="240"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="261"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR006250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006250-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP45574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY78518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="287" mass="29127" checksum="5DD4288597F73355" modified="2017-04-12" version="1">MSVERLIDTALDEDLALGPDVTTLSTVPPDAVGTADVVARQAGVVAGVNVAVAVARQAGRRLGVELEAAVVRNDGDRVAPGDVVLTVSGPVRGILTAERTLLNFLGQLSGVATATRQWADALAGTTARVRDTRKTVPGMRALQKAAVVAGGGVNHRMALGDAALIKDNHVAAAGSVGAAFRAVRAASPAIPIEVECDTVGQVREAVAAGADLILLDNMTLDELRESVAICRDAGVRTEASGGLTLADAAQVAATGVDFIAVGALTHSAPVLDLGLDLITGSPERFPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHM4</accession>
    <name>A0A1Q2CHM4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_13080</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyltransferase 87 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13080"/>
    <dbReference type="EnsemblBacteria" id="AQP45626">
        <property type="protein sequence ID" value="AQP45626"/>
        <property type="gene ID" value="RPIT_13080"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13080"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018584">
        <property type="entry name" value="GT87"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09594">
        <property type="entry name" value="GT87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="275"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="381"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="421" mass="46129" checksum="6F0829EC5DEB5719" modified="2017-04-12" version="1">MTHPARDAAATAMDRYLGSRALRGVAVVVFAWLVFVLVTAFPSTDPWATYRIDFDVYRMGGEAFLGGEDLYGQLFRTRSGAELFFTYPPIGAILFSLFSFVSFGAGAAILTGLSIASLVLSLWLVIRALGADGRDAFWLAVLAGILAVWTIPVRETVEHGQINLILMALVLGDVLGRRQRWWRGSLVGLALSIKLTPAVFLAYFLIRRDWRALAMGIGSALFYTGLGFLLAPDDSWRYWTSALISPERIGANAFATNQSLSGAIHRLGFDGAETVLWFVVCAIVGLACLALLRRLFNEGDAVMAAMVMGHYALLASPVSWGHHWVWSAPAVVVVLVWAWRCLPHWTGWALAGFAVAGAAVYLLAPHLWFPRPPQQNPNWSWWQQLVGSAYLWWAFGLLLVAWFAAPRAAAGGRSAPSETRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHS2</accession>
    <name>A0A1Q2CHS2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Menaquinone-dependent protoporphyrinogen oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13320</name>
        <name evidence="3" type="ORF">SAMN05428934_10423</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY75618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13320"/>
    <dbReference type="EnsemblBacteria" id="AQP45669">
        <property type="protein sequence ID" value="AQP45669"/>
        <property type="gene ID" value="RPIT_13320"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY75618">
        <property type="protein sequence ID" value="SDY75618"/>
        <property type="gene ID" value="SAMN05428934_10423"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13320"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026816">
        <property type="entry name" value="Flavodoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12724">
        <property type="entry name" value="Flavodoxin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin_5" evidence="1">
        <location>
            <begin position="5"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY75618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="161" mass="17458" checksum="23FA27A5516E517C" modified="2017-04-12" version="1">MATVLVAYATRGGTAHDIAEAVADVARDAGHDVTVADLRDKPHARADLVVVGSGVNAGSWYPEAVAWLARHTDTLRGTKVALFNACLNAADPAKREDSLAYNKVGVDRVGAVSSEAFAGRYVPHRVGWFRRVFLKTMQQQPQDHLDLDRVRAWAQGLLAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHW8</accession>
    <name>A0A1Q2CHW8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13510</name>
        <name evidence="3" type="ORF">SAMN05428934_11197</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ13328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13510"/>
    <dbReference type="EnsemblBacteria" id="AQP45701">
        <property type="protein sequence ID" value="AQP45701"/>
        <property type="gene ID" value="RPIT_13510"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ13328">
        <property type="protein sequence ID" value="SDZ13328"/>
        <property type="gene ID" value="SAMN05428934_11197"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13510"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041289">
        <property type="entry name" value="Bact_RF_family3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18845">
        <property type="entry name" value="baeRF_family3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ13328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="373" mass="41076" checksum="D8F4327E897D6B44" modified="2017-04-12" version="1">MTMKTIPNTDVLDSSFVEEALNHEGPWVSIFLPTHRTGRETMAALPQYQNLLKLAERALGEAGHGDRADELLEPARALLVDNRDFWRNQSDGLAVYAAPGLLRVFRLPIELPDEVAVGDAPRLRPLAMLLAQTNSFYVLALSPNAVRLFEATQSTIGELDLGEDTPASAEEVFTDRDHQTHLQHSPQSRGGDQANFHGHGGDDNAEEINVERFFRRVADAVGKVIDRTVVHPIVLATAEGNQSLYRSVSKHKHLLEDFVQGNPERLSPEELHAQAWPLAEKVLTADETELIERFGALKGTGKASDDLTLVGRAAAEGRVESLLLRARVSRPDGQADVVQDETDPVIADTLRNGGTVRVVEDDQAPEVRAIFRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHX0</accession>
    <name>A0A1Q2CHX0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Core-2/I-Branching enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_13615</name>
        <name evidence="7" type="ORF">SAMN05428934_11176</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13615"/>
    <dbReference type="EnsemblBacteria" id="AQP45719">
        <property type="protein sequence ID" value="AQP45719"/>
        <property type="gene ID" value="RPIT_13615"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12978">
        <property type="protein sequence ID" value="SDZ12978"/>
        <property type="gene ID" value="SAMN05428934_11176"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13615"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003406">
        <property type="entry name" value="Glyco_trans_14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02485">
        <property type="entry name" value="Branch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ12978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="309" mass="34717" checksum="A0C3E98818954C0F" modified="2017-04-12" version="1">MHGVVITAYRDFPQLASLLRALPDARVHVHLDRNAAFTQAQRRFLESLAHVVVASTYRVSWGGISHLRAIIDGVESLTQEPAIETIHILSGQDYPCRPLSTYSDIRDPQRAYLSLTAVTDQPVLLRRFRTRFEFPDQDLRDPAVRAGDALSIERQERSGNVRTTLGSMQRLYKGMVWGSLPADMARYCVKVARTDRAFMDDLVHSRIPEEFFFQTVLMNSPLAPRVSPNATTFMLWTPGRAVNSGPAVLNIGDLDQILASDKVFVRKVDSTDSAELVAALADRIGASPWSPPVERRFALWRFDAGRARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHX2</accession>
    <name>A0A1Q2CHX2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">CopG family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_13460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13460"/>
    <dbReference type="EnsemblBacteria" id="AQP45694">
        <property type="protein sequence ID" value="AQP45694"/>
        <property type="gene ID" value="RPIT_13460"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13460"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.10.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038296">
        <property type="entry name" value="ParD_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="73" mass="7855" checksum="57214B8B93C416ED" modified="2017-04-12" version="1">MADMVRAKVVSGECASESEVIRDGLRALAARDRAVDAWLLEQVAPAYDRMLADPDGALSVGEVRARLVSLRGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI20</accession>
    <name>A0A1Q2CI20_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_13560</name>
        <name evidence="10" type="ORF">SAMN05428934_11187</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ13156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13560"/>
    <dbReference type="EnsemblBacteria" id="AQP45710">
        <property type="protein sequence ID" value="AQP45710"/>
        <property type="gene ID" value="RPIT_13560"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ13156">
        <property type="protein sequence ID" value="SDZ13156"/>
        <property type="gene ID" value="SAMN05428934_11187"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13560"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023845">
        <property type="entry name" value="DUF3817_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12823">
        <property type="entry name" value="DUF3817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03954">
        <property type="entry name" value="integ_memb_HG"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
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        <location>
            <begin position="24"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ13156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="122" mass="13745" checksum="F8FFAB162F8D2EA9" modified="2017-04-12" version="1">MNEYESRSDIVDPEDIPGIRGALLRYRVMAWVVGILLVILMCVGLPLKYIWGDGRVVTWTGVPHGWLYAVLLITAYDLGRRVGWPIKWFLGIMAAGTVPFLSFVAEHFATKHVRSVIERSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI53</accession>
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        <submittedName>
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        <name evidence="3" type="ORF">SAMN05428934_11152</name>
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        <name type="scientific">Tessaracoccus flavus</name>
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        <lineage>
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    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ12557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="186" mass="20188" checksum="E2EE9655B35A8020" modified="2017-04-12" version="1">MKRAVHPQTIPGEHQAVRWVTETNLPVGRVTHAPGTVGPMLEYGVLTKMLVERGGVWTWLAADHSWTEHGPRIRDAVAASLDLEGWEIEESPELLGLIAREVLEGELAGYVSSHGGHITVSTATATTLVLDFGGACEDCPAAGSTLHDRIEKTVRERYPSLVEVKRVGGEHHSRGWLGLPIPGRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI76</accession>
    <name>A0A1Q2CI76_9ACTN</name>
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            <fullName evidence="2">Uncharacterized protein</fullName>
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    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">RP1</strain>
        </source>
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    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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    </dbReference>
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        <location>
            <begin position="44"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="AQP45829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ14943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="78" mass="8498" checksum="55546A876F51B705" modified="2017-04-12" version="1">MGERKAVLLRLDPAVHDALARWAADDLRSVNAQIEVVLRDALKKAGRAPKDAAPLPKRGRPPAQPRSPSGKGHHRLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI85</accession>
    <name>A0A1Q2CI85_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">RPIT_13915</name>
        <name evidence="3" type="ORF">SAMN05428934_11117</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
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        <lineage>
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    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP45765.1"/>
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    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13915"/>
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        <property type="gene ID" value="RPIT_13915"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ11892"/>
        <property type="gene ID" value="SAMN05428934_11117"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="entry name" value="Glycos_transf_2"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="7"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ11892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="117" mass="12276" checksum="F4AF24274ECD9CF2" modified="2017-04-12" version="1">MNTPAISVIVPVYNVAPYLTQCLDSVLAQTFGDFELLLVDDGSTDGSSALCDAYAARDDRVRVVHQPNAGLSAARNAGLKLALGEFITFLDGDDWFDAATLAVARQTALASGADVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIC2</accession>
    <name>A0A1Q2CIC2_9ACTN</name>
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        <recommendedName>
            <fullName evidence="9">Branched-chain-amino-acid transaminase</fullName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">RPIT_14255</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14255"/>
    <dbReference type="EnsemblBacteria" id="AQP45823">
        <property type="protein sequence ID" value="AQP45823"/>
        <property type="gene ID" value="RPIT_14255"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14255"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00058"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00073"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00062"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052656">
        <property type="term" value="F:L-isoleucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052654">
        <property type="term" value="F:L-leucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052655">
        <property type="term" value="F:L-valine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825">
        <property type="entry name" value="PTHR11825"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01123">
        <property type="entry name" value="ilvE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="12" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 14" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="13">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00005072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00013053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR006468-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="AQP45823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="357" mass="39147" checksum="8A62629286A9EED9" modified="2017-04-12" version="1">MPMFQVTRTATSTSDAARQAALADPGFGRYYVDHMAVVDYVAGDGWQEPRIVPMTEWALHPAAAVMHYGQEIFEGLKAYRRDDDSIWLFRPERNAARFVTSAQRMGMAVLPEELFLASVTELVDMEREWVPTSENEQSLYIRPFMIASEPYLGVREANTYRYAVIATPAGPYYSEPMKLWITPNYTRAAPGGTGTAKCGGNYAASLIATQEAYANGCGQVLWTDGAEHKWIEECGTMNVMFVTADGELVTPALGSILAGVTRESILMLAADHGLTAVERPISVDELLDGLESGQITEVFACGTAAVVTPIVGFNSPQRGEQVVADGQPGPKTREIRQHLVDIQYGRAEDKHGWTVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIG8</accession>
    <name>A0A1Q2CIG8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein N-acetyltransferase, RimJ/RimL family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14810</name>
        <name evidence="3" type="ORF">SAMN05428934_10958</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14810"/>
    <dbReference type="EnsemblBacteria" id="AQP45919">
        <property type="protein sequence ID" value="AQP45919"/>
        <property type="gene ID" value="RPIT_14810"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05688">
        <property type="protein sequence ID" value="SDZ05688"/>
        <property type="gene ID" value="SAMN05428934_10958"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14810"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ05688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="170" mass="18941" checksum="5F2652CBE960B338" modified="2017-04-12" version="1">MRPEPFPFGPLSSDRLRLDPLRVDDADEMVGVLADPGLYRYTGFETPPSLDELRERYRRLTAGPPPPWADLWLNWIVRAEGVAVGYVQATVKGESADVAWVIGTRHQGLGYATEASRMMLRALDDGGVRTFRAYIHPRNAPSQAVAAHLGMRKLPGQPFDGEDLWETHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIH2</accession>
    <name>A0A1Q2CIH2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Biotin-lipoyl like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_14770</name>
        <name evidence="4" type="ORF">SAMN05428934_10966</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14770"/>
    <dbReference type="EnsemblBacteria" id="AQP45911">
        <property type="protein sequence ID" value="AQP45911"/>
        <property type="gene ID" value="RPIT_14770"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05839">
        <property type="protein sequence ID" value="SDZ05839"/>
        <property type="gene ID" value="SAMN05428934_10966"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14770"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="2">
        <location>
            <begin position="46"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ05839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="245" mass="25893" checksum="B69844EB67A1071A" modified="2017-04-12" version="1">MSWIARLKLLLGILVVVVIVAALTLLFNYRQNQVASIEASVEAPTSAIASSYGGVVVEQLVNPGDEVKAGQDLFVVNSPALQEAVARGVTPASTPAFTLDTDAGTVTYHAVSDGYLTDFVGFEGTFLNNGDRLASVVSQGNKAVRALFELNPFDYGRIEPGANVTIHLPDGSRADGEVAGVDVRREGSSTVTTVTVQSESLQDPEVELLTRRGTPVHAVMSLRDDGVLAGPSQALKDFLLKIGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIL0</accession>
    <name>A0A1Q2CIL0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_01305</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="AQP45951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP45951">
        <property type="protein sequence ID" value="AQP45951"/>
        <property type="gene ID" value="RPIT_01305"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01305"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
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        <location>
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            <end position="76"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="143"/>
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            <end position="225"/>
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            <end position="258"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="285"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
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            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="328" mass="33722" checksum="0CCBEEC54F1BC8FE" modified="2017-04-12" version="1">MALVALLVANTIYRPSFLAVTIRDGHLFGSPIDILRNSSPLLLVALGMTLVIATRGIDLSVGAVVAISGALSLSYIQSSANPDSPFTVLVAVAVALGVCLALGAWNGFMVAVLGIQPIIATLILMMAGRGIAMLITGGFITTVNSGPYKWLGSGWVLGLPVPFWIAAAMFTIVMLLCRKGALGMLIEAVGINPAAARLAGVRARVITWTVYIVAGLFAGIAGLLLSANVMAADANNAGLFIELDAILAVVIGGTSLAGGKFSLSGTAVGVFIITTLTLTVTMLGISPLITPLFKAVVVILVTLLQSPVAREKLESMGRRRAAQGKAAE</sequence>
</entry>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">RP1T</strain>
        </source>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="118" mass="12955" checksum="590EFBA7985D37BC" modified="2017-04-12" version="1">MLGNPLIRLLLRRIDRSAEPDDVEQARANLGLVQAQKELPGGRWVGILERLAVYACIVASFPAGIAMVLAVKGLGRYADLVTESDRSRKGELFIIGTFASMLWAALWGGIAYWGVRAW</sequence>
</entry>
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    <accession>A0A1Q2CIM9</accession>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_14735</name>
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    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14735"/>
    <dbReference type="EnsemblBacteria" id="AQP45905">
        <property type="protein sequence ID" value="AQP45905"/>
        <property type="gene ID" value="RPIT_14735"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05977">
        <property type="protein sequence ID" value="SDZ05977"/>
        <property type="gene ID" value="SAMN05428934_10973"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14735"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Peptide/Ni-bd"/>
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        <property type="entry name" value="SBP_5"/>
    </dbReference>
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        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        </location>
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            <end position="556"/>
        </location>
    </feature>
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        <location>
            <begin position="103"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ05977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="556" mass="59810" checksum="167647275ACBECDF" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIP2</accession>
    <name>A0A1Q2CIP2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LacI family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_02075</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
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    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP45974">
        <property type="protein sequence ID" value="AQP45974"/>
        <property type="gene ID" value="RPIT_02075"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02075"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
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        <property type="entry name" value="LacI/GalR-like_sensor"/>
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        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Peripla_BP_I"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="5"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="328" mass="34163" checksum="6FAB183464D787AF" modified="2017-04-12" version="1">MPSRARLADLATAAGVSTATVSRVLNGKPGVAKTTRAQVISTIEALGYQLEDETPAHEGFVAVILPELANPSFAAFATELSLQLSAADRHMILCTSGPGATSEVSYLDALLSVNVAGIISVSGTLADSLASPEHYRRVAGDVPAVFINGYDETVPGAFFSSSDAGAVAMSVAHLRSFGHERIGLAVGQERYLPTQRKVAAFRALGFPRTSIASTIFSVEGGQAAAARLYESGHTAIICGSDVMALGAIREARARGLDVPGDISVVGYDDSALMAFTSPALTTVRQPLPAMCQAAVSALLAAMRGLPLEHTEMMFHPDLIIRQSTGPHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIP6</accession>
    <name>A0A1Q2CIP6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphoserine phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">O-phosphoserine phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">RPIT_00765</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + O-phospho-D-serine = D-serine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24873"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35247"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58680"/>
            <dbReference type="EC" id="3.1.3.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + O-phospho-L-serine = L-serine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21208"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57524"/>
            <dbReference type="EC" id="3.1.3.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the HAD-like hydrolase superfamily. SerB family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.3" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00765"/>
    <dbReference type="EnsemblBacteria" id="AQP45943">
        <property type="protein sequence ID" value="AQP45943"/>
        <property type="gene ID" value="RPIT_00765"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00765"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00198"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036424">
        <property type="term" value="F:L-phosphoserine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004469">
        <property type="entry name" value="PSP"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00029">
        <property type="entry name" value="phosphoserine_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00338">
        <property type="entry name" value="serB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0718">Serine biosynthesis</keyword>
    <feature type="active site" description="Nucleophile" evidence="13">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="13">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR604469-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="AQP45943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="282" mass="29349" checksum="CFD1DDE0FD058A4E" modified="2017-04-12" version="1">MASQGPIPTSLVSLVPTPEYVISDQTPYGHRTSILTSHDDPDALRTALRAFAGNVAVAVITGPLALQRAKLLLMDVDSTLTTTEAIDLLADHAGVGEKVAEITGRAMRGELDFTSSLTERVATLDGLPTSVFDEVAAAMTLSDGAEELIRTAQSAGAKVGVTSGGFTQLVAPLAQRLGLDFYNANDLETVTADGVERLTGRCVGSVVDRDQKARDLLRFAHDNSIDPALTVAVGDGANDLAMFAAAGLSVAYCAKPVTAAKADVSLNFPRLDAVAPFAFAGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIU3</accession>
    <name>A0A1Q2CIU3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Meth_synt_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06525"/>
    <dbReference type="EnsemblBacteria" id="AQP46058">
        <property type="protein sequence ID" value="AQP46058"/>
        <property type="gene ID" value="RPIT_06525"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06525"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003871">
        <property type="term" value="F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002629">
        <property type="entry name" value="Met_Synth_C/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01717">
        <property type="entry name" value="Meth_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="SSF51726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Meth_synt_2" evidence="1">
        <location>
            <begin position="95"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="298" mass="31842" checksum="7214B338C47A06CE" modified="2017-04-12" version="1">MTDLLPEVLPLPELPARGPGSDLVGRALGLIDGLGFDVQPAGWRLAHHAGSEHRRARAQWRRDLDDAEELLQGFGGTLKVAVGGPWTLAASVERPTGDRLLADHGARRELAEALAEGTTLLRADLGRRLPEATVLIQIDEPALLAVRDGEIPTASGFSRHRRVDPPELVGALRPMATGALLHCCAPGRWAELARRAGFDSIGVDSRLSHLDDLGEWLDGGGTLVLGVVETASAVPQSVDQLVDETLRVVRRLQIADPGERLLLGTACGLAGWDPRDIAPQLRALRRAAELSAEALLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIV5</accession>
    <name>A0A1Q2CIV5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">Protein translocase subunit SecA</fullName>
            <ecNumber evidence="14">7.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">secA</name>
        <name evidence="20" type="ORF">RPIT_05355</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="14">Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Peripheral membrane protein</topology>
            <orientation evidence="14">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="14">Distribution is 50-50.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14 15">Belongs to the SecA family.</text>
    </comment>
    <dbReference type="EC" id="7.4.2.8" evidence="14"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05355"/>
    <dbReference type="EnsemblBacteria" id="AQP46034">
        <property type="protein sequence ID" value="AQP46034"/>
        <property type="gene ID" value="RPIT_05355"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05355"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017038">
        <property type="term" value="P:protein import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18803">
        <property type="entry name" value="SF2_C_secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01382">
        <property type="entry name" value="SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004027">
        <property type="entry name" value="SEC_C_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000185">
        <property type="entry name" value="SecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020937">
        <property type="entry name" value="SecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011115">
        <property type="entry name" value="SecA_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014018">
        <property type="entry name" value="SecA_motor_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011130">
        <property type="entry name" value="SecA_preprotein_X-link_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044722">
        <property type="entry name" value="SecA_SF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011116">
        <property type="entry name" value="SecA_Wing/Scaffold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036266">
        <property type="entry name" value="SecA_Wing/Scaffold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036670">
        <property type="entry name" value="SecA_X-link_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30612">
        <property type="entry name" value="PTHR30612"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02810">
        <property type="entry name" value="SEC-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07517">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01043">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07516">
        <property type="entry name" value="SecA_SW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00906">
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    </dbReference>
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            <end position="242"/>
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            <end position="616"/>
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        <location>
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        </location>
    </feature>
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        <location>
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            <end position="881"/>
        </location>
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        <location>
            <begin position="884"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="82"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        <location>
            <begin position="100"/>
            <end position="104"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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    <feature type="binding site" evidence="14">
        <location>
            <position position="489"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00007650"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022723"/>
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        <source>
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        <source>
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        <source>
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        <source>
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        <source>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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        </source>
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        </source>
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            <dbReference type="EMBL" id="AQP46034.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="929" mass="104288" checksum="3BDC9564734217A3" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ17</accession>
    <name>A0A1Q2CJ17_9ACTN</name>
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        <submittedName>
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        </submittedName>
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    </gene>
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        <name type="scientific">Tessaracoccus flavus</name>
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        <lineage>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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    </comment>
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    </dbReference>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP46138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="318" mass="35141" checksum="E2656BA6CD9AF66B" modified="2017-04-12" version="1">MTASARAGRPRVGRADWLKRGEIILLAGPAIVMFSGFVIFPVFMAAYYGFFRWKGFGPPTDFIGLQNYVTILTDQLFLSAMQHNAFIVVLSLVMQGPIAIAFALLLNQQIKGRSLIRVLIFVPYVIAEVIVGTGWGLMLQTTGAVNDFLGKIGLESLQADWIADPKIAIWTLMVIISWKYIGFAVILMLAGMQGIPDELYEAAAVDGASYWQIQRSITLPLLGPTIRIWAFLSIIGSLQLFDLVYIIWGQYVADTAGTSTMATYMVREGRLTGNYGYGNAVAVVIFLISLVIALTYQRFVLRRDTEGALTEKPGKDKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
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    <protein>
        <submittedName>
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            <taxon>Bacteria</taxon>
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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                <person name="Singh P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
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        <property type="gene ID" value="RPIT_07095"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DeoR_C"/>
    </dbReference>
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        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP46065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="253" mass="26736" checksum="A622B28F65E5C275" modified="2017-04-12" version="1">MVALLALLSEQGQLPLSQLADALGASAATIRRDVALLAAQGLLERTHGGARPVKGNRELPVRLRDGRNQDAKRRIARMVASLIPTGKHAIGLTGGTTTAEVLRALRHRDDLTIITNSLSIGLEAAEQGQARVLIAGGVLRPNSLELVGSLAESTMKLVNVGTAVIGVDGISAEGGLTTHDEIEARTNYAMIERAQRVIVAVDSTKVGNTTLAKMADFSEIQILVTDSGAPDTQLDRFRDAGVEVHVVEGPKHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ89</accession>
    <name>A0A1Q2CJ89_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase_M23 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13660"/>
    <dbReference type="EnsemblBacteria" id="AQP46172">
        <property type="protein sequence ID" value="AQP46172"/>
        <property type="gene ID" value="RPIT_13660"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13660"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="42"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="342" mass="34126" checksum="7D9C68D993CE700E" modified="2017-04-12" version="1">MAPGVDTLGKPAPGTLLSTPVNGRESSRFGMRFHPTLRVWKLHTGLDWAAPCGTPVGAAADGKVVRVGWAGGNGFQVKIDHGTIAGYRLTTTYNHLQSSAVRVGQQVKALSAIAEVGNNGNSTGCHLHFEVIANGRFTDPKLWLSGSAAVIDLDAASEFEPASSLPVSQRPSTTASATPSASPSASIGPSVRPSPSPSPSPSPSVSPSPSPSPSPSASAVPSPQPSASPEPSPSVAPSASPSASPNPSASPEPEPSAPSSPEPPASVTPSPTETAVPSPTPSEPAEPPAPPSTQPTTSRTATATTPPPPADEPTPPAPPAPEPEPEPSAPAEPAPTPSSTEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJE9</accession>
    <name>A0A1Q2CJE9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13130"/>
    <dbReference type="EnsemblBacteria" id="AQP46165">
        <property type="protein sequence ID" value="AQP46165"/>
        <property type="gene ID" value="RPIT_13130"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13130"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009937">
        <property type="entry name" value="Phage_holin_3_6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07332">
        <property type="entry name" value="Phage_holin_3_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="146" mass="15468" checksum="0698F3F1C389E418" modified="2017-04-12" version="1">MNEEEASYLRYREEDRSLGEIASDLLDNATTLIRQEVELAKVEAKESATKAGKGVGMLAGAGVAGLLALIALTLTAWWGMAVLIGSSDDPALGWGGLIVTIIWLVIAGILAAVGKGELNKVRGLKQTQETVKKIPNAATGHEEKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBE6</accession>
    <name>A0A1Q2CBE6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA_LIGASE_A3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00160"/>
    <dbReference type="EnsemblBacteria" id="AQP43430">
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        <property type="gene ID" value="RPIT_00160"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_LIGASE_A3" evidence="2">
        <location>
            <begin position="19"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="207" mass="21495" checksum="B9E3751DEF801958" modified="2017-04-12" version="1">MGNIQEAADPVGDAVDFACEFPELVEAIIENFPDHSAIDGEIIMIDPESGDRLNFDALQQRIHPAESRIKKLSAAMPASFVAFDLLALGQTNYVNAAKTVASNNGSLASNGSEYYRRTCAAARVISMSLQAVVADLGGRVAGDAANALSQQLDQARSSSTVLSPGSWPTGTQGGAAGPDNMNTVSNPQNVDTSSATTGPTDTTGVNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBG0</accession>
    <name>A0A1Q2CBG0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00235</name>
        <name evidence="3" type="ORF">SAMN05428934_1053</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY83454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43442">
        <property type="protein sequence ID" value="AQP43442"/>
        <property type="gene ID" value="RPIT_00235"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY83454">
        <property type="protein sequence ID" value="SDY83454"/>
        <property type="gene ID" value="SAMN05428934_1053"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00235"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544391" evidence="1">
        <location>
            <begin position="28"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY83454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="104" mass="11665" checksum="890EDA3815FAA672" modified="2017-04-12" version="1">MAKNKIRIAFTALLVSLLALTALPAQAWSWMDYQENFSLKSNCQARGQWLVKNVVDLGAFECRYNSKSRTYRLWVLRDDEFGCRTALSATRKSITAPQGCGGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBI0</accession>
    <name>A0A1Q2CBI0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00405</name>
        <name evidence="3" type="ORF">SAMN05428934_10535</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY84361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43464">
        <property type="protein sequence ID" value="AQP43464"/>
        <property type="gene ID" value="RPIT_00405"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY84361">
        <property type="protein sequence ID" value="SDY84361"/>
        <property type="gene ID" value="SAMN05428934_10535"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00405"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY84361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="92" mass="9874" checksum="7F4A01AE8D892C54" modified="2017-04-12" version="1">MNVDISHGRPGQPVRRASIPTDDGLAEGLARLTAAQDALASLLADLQSELNGTSALWGERARQAYVEAQRSWEASTARQRQIVADIPAHARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBJ6</accession>
    <name>A0A1Q2CBJ6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00470</name>
        <name evidence="3" type="ORF">SAMN05428934_10548</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY84711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43477">
        <property type="protein sequence ID" value="AQP43477"/>
        <property type="gene ID" value="RPIT_00470"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY84711">
        <property type="protein sequence ID" value="SDY84711"/>
        <property type="gene ID" value="SAMN05428934_10548"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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        <location>
            <begin position="9"/>
            <end position="30"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="AQP43477.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY84711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="143" mass="15221" checksum="A471849BF1E1A359" modified="2017-04-12" version="1">MWRMNRTRLAYSAVTVVGAIAALAAAGLAIGGLGNWALACLAVAVLGLQAAGHLRNRMRIASDRKALLAALNRIGRVERMVSEMVDRAAPPADWGQQLEATELRSRTELAAIRSTLTSLSASFADVQRAAIEARAVANQQRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBK4</accession>
    <name>A0A1Q2CBK4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00130</name>
        <name evidence="3" type="ORF">SAMN05428934_10919</name>
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    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ04893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="AQP43425"/>
        <property type="gene ID" value="RPIT_00130"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ04893"/>
        <property type="gene ID" value="SAMN05428934_10919"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="17"/>
            <end position="99"/>
        </location>
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    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13601"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP43425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ04893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="111" mass="11880" checksum="808386E7478ED3AC" modified="2017-04-12" version="1">MTQVEARFDELIHFPARLRVCGLLRNVDALAFRVLEEALQLPAPQVSRHLKALSEAGYVTVSKTASSERSDARRVAWVCLTPAGRQALDGHMAALEQIVGGSAAAHDGSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBK6</accession>
    <name>A0A1Q2CBK6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00560</name>
        <name evidence="3" type="ORF">SAMN05428934_10566</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY85172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00560"/>
    <dbReference type="EnsemblBacteria" id="AQP43494">
        <property type="protein sequence ID" value="AQP43494"/>
        <property type="gene ID" value="RPIT_00560"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY85172">
        <property type="protein sequence ID" value="SDY85172"/>
        <property type="gene ID" value="SAMN05428934_10566"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00560"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="17"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY85172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="78" mass="8460" checksum="25B7AFBD39950CC0" modified="2017-04-12" version="1">MVPGKRAGEAQEINLRMRGARAAKGLTQADLAKLVGASRQTISLIEAGAHNPTLRLCIDIARALDTDLNTLFWEESEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBM9</accession>
    <name>A0A1Q2CBM9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Polyphosphate glucokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00655</name>
        <name evidence="2" type="ORF">SAMN05428934_10584</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY85668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00655"/>
    <dbReference type="EnsemblBacteria" id="AQP43510">
        <property type="protein sequence ID" value="AQP43510"/>
        <property type="gene ID" value="RPIT_00655"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY85668">
        <property type="protein sequence ID" value="SDY85668"/>
        <property type="gene ID" value="SAMN05428934_10584"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00655"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY85668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="256" mass="27217" checksum="4F70AD5E1B0EE45E" modified="2017-04-12" version="1">MSIFLGIDVGGSGIKGAPVDLTQGDFAADRLRIPTPAKSTPKNVAQVIGEIIEAFSDEIGDNPVGLTIPAPVVHGRVPFIANLDQKWAGLQADEYFEDALGRPITLVNDADAAGLAEVHFGAAKGHEGLVILTTLGTGIGSAIIYRGVLIPNAELGHVELAGYDAERRAASSIKDKEGLSYEEWATERLQPYYAHLEMLFSPDLFVVGGGVSKDWNQFGDLLNLKTEIIPAKLRNRAGIIGAALAAQDAQEHPDLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBN9</accession>
    <name>A0A1Q2CBN9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA ligase (ATP)</fullName>
            <ecNumber evidence="1">6.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_00740</name>
        <name evidence="5" type="ORF">SAMN05428934_105101</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.5.1.1" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00740"/>
    <dbReference type="EnsemblBacteria" id="AQP43526">
        <property type="protein sequence ID" value="AQP43526"/>
        <property type="gene ID" value="RPIT_00740"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86120">
        <property type="protein sequence ID" value="SDY86120"/>
        <property type="gene ID" value="SAMN05428934_105101"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00740"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014146">
        <property type="entry name" value="LigD_ligase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02779">
        <property type="entry name" value="NHEJ_ligase_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_LIGASE_A3" evidence="3">
        <location>
            <begin position="102"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY86120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="322" mass="35225" checksum="FD01AB2F441EA681" modified="2017-04-12" version="1">MRPMLATPTSTPGQPPTGPGWVHEVKWDGIRAIATIRDGQVRLTNRNEGDISVAYPEVVRGGAGLPDCTIDGELIALDDQGRPSFHVIAHRMHARNPTRIVRHAAERPVTFVAFDLLELGGRRLTSLPLTERRSLLETLDLNRPAWQLSDLFDDGDALAAHTREAGLEGILSKRADSPYLEGVRSPHWVKTPHRSEMIAVIGGWIPETDSPGKLGALWVGHPSDEDTFEANPVLYPVGRVGSGLGHAQRDVLLQVLKDTERPTPPFDPAPTGPDARRSRWVEPMLCVHVRYLNVTPDGVLRQPVLLALRPDISPVAAATTVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBS7</accession>
    <name>A0A1Q2CBS7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycosyltransferase involved in cell wall bisynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_00920</name>
        <name evidence="6" type="ORF">SAMN05428934_105136</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00920"/>
    <dbReference type="EnsemblBacteria" id="AQP43558">
        <property type="protein sequence ID" value="AQP43558"/>
        <property type="gene ID" value="RPIT_00920"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87050">
        <property type="protein sequence ID" value="SDY87050"/>
        <property type="gene ID" value="SAMN05428934_105136"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00920"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="4">
        <location>
            <begin position="181"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="3">
        <location>
            <begin position="518"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY87050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="629" mass="65566" checksum="E76867451B1090B3" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBV2</accession>
    <name>A0A1Q2CBV2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate ABC transporter substrate-binding protein, CUT1 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Sugar ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01060</name>
        <name evidence="3" type="ORF">SAMN05428934_105163</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01060"/>
    <dbReference type="EnsemblBacteria" id="AQP43582">
        <property type="protein sequence ID" value="AQP43582"/>
        <property type="gene ID" value="RPIT_01060"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87788">
        <property type="protein sequence ID" value="SDY87788"/>
        <property type="gene ID" value="SAMN05428934_105163"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01060"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544410" evidence="1">
        <location>
            <begin position="27"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY87788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="424" mass="46454" checksum="E0D2FDF8EDF54AB6" modified="2017-04-12" version="1">MSSPFRLSRRQLLVAGGLTLGTSALAACGGGSSSTGETSSIVKVGSYQSDEIPKQAFADMMAAFEGGDVEINTIQHETFKEGINNYLQGNPDDVFTWFAGYRARYFAERGLVGDLSDVWANIDGMPESMKVASTSGDGKQVFIPSTYYPWAVFYRPSLFQERGYTEPTTIDEWITLNERMLADGLTPIGFADKDGWEAMGTFDMLNLRVNGYDYHVSLMAGEEAWDGDKVKNVFKLWSDLMPYHEADSLGRTWQEAAQGLIQNRTGVYVMGMFVQQQFAAAGLEDDLDFFIFPEADPAIGAKVVEAPVDGFMMAADPKNPELAKELLAYLATPEAVAHTVKADPSVIAANSKADQSSYNALQKKAVKVIEEAEAISQFLDRDSRPDFANTVVGPALQSFIQDPSQIDSILSNVEEQKKSIFASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBX0</accession>
    <name>A0A1Q2CBX0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Recombination protein RecR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">recR</name>
        <name evidence="9" type="ORF">RPIT_01210</name>
        <name evidence="10" type="ORF">SAMN05428934_105191</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the RecR family.</text>
    </comment>
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        <property type="protein sequence ID" value="AQP43606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY88453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01210"/>
    <dbReference type="EnsemblBacteria" id="AQP43606">
        <property type="protein sequence ID" value="AQP43606"/>
        <property type="gene ID" value="RPIT_01210"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY88453">
        <property type="protein sequence ID" value="SDY88453"/>
        <property type="gene ID" value="SAMN05428934_105191"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01210"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="entry name" value="TOPRIM_recR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000093">
        <property type="entry name" value="DNA_Rcmb_RecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023627">
        <property type="entry name" value="Rcmb_RecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023628">
        <property type="entry name" value="Rcmb_RecR_C4-type_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015967">
        <property type="entry name" value="Rcmb_RecR_CS"/>
    </dbReference>
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        <property type="entry name" value="TOPRIM_domain"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR30446">
        <property type="entry name" value="PTHR30446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02132">
        <property type="entry name" value="RecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13662">
        <property type="entry name" value="Toprim_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111304">
        <property type="entry name" value="SSF111304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00615">
        <property type="entry name" value="recR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01300">
        <property type="entry name" value="RECR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="8">
        <location>
            <begin position="79"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="7">
        <location>
            <begin position="56"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP43606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY88453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="204" mass="22839" checksum="AA4E200E26448205" modified="2017-04-12" version="1">MYEGPIQDLIDELSRLPGIGPRGAQRIAFYLLDAPEEDVYTLADTLRRVKETSRFCEVCFNISQEARCRVCRDPRRDRTQLCVVEESKDVVAIERTNEFRGLYHVLGGSISPIDGRGPSDLHTRELFQRLADGEIVEVILATDPDTQGEATASYLSRMLRDFGVRVTRPASGLPVGGDLEYADQVTLGRAFEGRRSMFEPEPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC05</accession>
    <name>A0A1Q2CC05_9ACTN</name>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_01020</name>
        <name evidence="6" type="ORF">SAMN05428934_105155</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01020"/>
    <dbReference type="EnsemblBacteria" id="AQP43575">
        <property type="protein sequence ID" value="AQP43575"/>
        <property type="gene ID" value="RPIT_01020"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87569">
        <property type="protein sequence ID" value="SDY87569"/>
        <property type="gene ID" value="SAMN05428934_105155"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01020"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="14"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY87569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="227" mass="25080" checksum="86F2C9CF2BD56688" modified="2017-04-12" version="1">MSASGPRQLVDSVPSLVDVALDYIRTRIATGEYAPGHRLKERELSDETGISRIPIREAIRALASEGFVTLVPRRGAIVTELRPDLLDEIFEVREALEVQECVLAAQRATRDEVATMRASVEAAEEAARVGNAEGVNDANARFHEILVDASHNDTLAQVLRPLKNRLNWILRQNDDVTLVCREHRDILEAIASGDVERAREVATSHVRTSKQIALAVLFEDRELSASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC41</accession>
    <name>A0A1Q2CC41_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HEAT repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_01645</name>
        <name evidence="2" type="ORF">SAMN05428934_10878</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01645"/>
    <dbReference type="EnsemblBacteria" id="AQP43672">
        <property type="protein sequence ID" value="AQP43672"/>
        <property type="gene ID" value="RPIT_01645"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02392">
        <property type="protein sequence ID" value="SDZ02392"/>
        <property type="gene ID" value="SAMN05428934_10878"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01645"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03130">
        <property type="entry name" value="HEAT_PBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ02392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="257" mass="27330" checksum="30B7714A7CA63A51" modified="2017-04-12" version="1">MKYDVTTLINQLDSSVGTDRRHAALALGALQGPEIVPALLAHLKSETDGRVKEDLTWAIVQHADDANDEILALLASESEHERFTGAHVVSKVANPDHFEHVRPLVADTHADVAIKAYRAAANTGGPRAADALAERLGDGDDWQRDALSDAFRRLGEHGVDALVKRLADADAVVRHHAADALGYVGGPEADAAATALETATTDDDPEVRLAAVSALGQLAFAADEPLQRIAEGDDAVLSAIAKRFLEERPAQDPSARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC44</accession>
    <name>A0A1Q2CC44_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01670"/>
    <dbReference type="EnsemblBacteria" id="AQP43676">
        <property type="protein sequence ID" value="AQP43676"/>
        <property type="gene ID" value="RPIT_01670"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01670"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="295" mass="32212" checksum="538B86364D2C1B56" modified="2017-04-12" version="1">MRRFIRSERLREAALASGVAEEFAKLYVAGDDASGAAEVARRLRSHGLLISLAYLPRSDDEAETPEKLGEALGALGDAADGAELSVKPSSLGIRTDAASAAARLADLCQAAAERGSVVTLEMQGIDHYQATIDLWQAAVSSHASLGLTLPADIRRAERDVARLAPDGARLRLCVGSYPVPPSLGYRTEREKFRALVRTLRLTMENGGYAMLASHHPTVIAIAQDLARRNGVGRDGFEFQMFHGVRPLEQRRLTDVGYRSRTYLPFGPAWFEYLTTKVAARPRSAFSYLRAVADKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC72</accession>
    <name>A0A1Q2CC72_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 8">Adenylosuccinate synthetase</fullName>
            <shortName evidence="7">AMPSase</shortName>
            <shortName evidence="7">AdSS</shortName>
            <ecNumber evidence="7 8">6.3.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">IMP--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">purA</name>
        <name evidence="9" type="ORF">RPIT_01875</name>
        <name evidence="10" type="ORF">SAMN05428934_108123</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.3.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 8">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the adenylosuccinate synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.4" evidence="7 8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ03302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01875"/>
    <dbReference type="EnsemblBacteria" id="AQP43709">
        <property type="protein sequence ID" value="AQP43709"/>
        <property type="gene ID" value="RPIT_01875"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ03302">
        <property type="protein sequence ID" value="SDZ03302"/>
        <property type="gene ID" value="SAMN05428934_108123"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01875"/>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004019">
        <property type="term" value="F:adenylosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03108">
        <property type="entry name" value="AdSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00011">
        <property type="entry name" value="Adenylosucc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018220">
        <property type="entry name" value="Adenylosuccin_syn_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042109">
        <property type="entry name" value="Adenylosuccinate_synth_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042110">
        <property type="entry name" value="Adenylosuccinate_synth_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042111">
        <property type="entry name" value="Adenylosuccinate_synth_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001114">
        <property type="entry name" value="Adenylosuccinate_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846">
        <property type="entry name" value="PTHR11846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00709">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00788">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00184">
        <property type="entry name" value="purA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01266">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 7 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 7 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="IMP binding" evidence="7">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7">
        <location>
            <begin position="38"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="298"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="12"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="40"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="330"/>
            <end position="332"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="412"/>
            <end position="414"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP43709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ03302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="427" mass="46560" checksum="4ABF513E318A347A" modified="2017-04-12" version="1">MPSVVVVGAQWGDEGKGKATDQLGDRVDVCVRYSGGNNAGHTLVVGGEKFVLHLLPSGILNRNTTTVIGNGVVVDLDVLAEELKVLSDRGVDVPHPLISANAHIITEYHKVIDKVTERFLGKRKIGTTGRGVGPCYSDKVNRLGIRIQDILDESILRQKVEAALDQKNQLLVKVYNRREIDAEGVVQSLLKHADVIRPHIVDSGRYVNDALDEGKVVLFEGAQAHHLDVDQGTYPYVTSSNPTAAGATTGGGVGPTRIDRTIGIAKAYTTRVGEGPFPTELFDEDGEKLRRIGAEFGATTGRPRRCGWFDALLVEQAVKINGFTDIFLTKLDILSGWEKIPVCVAYEVDGVRHDVMPMTQSDFHHAKPVYEYLDGWAEDISGCRVFDELPPTCQAYVHRLEELIGCRISGIGVGPGREQSVAIHDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC85</accession>
    <name>A0A1Q2CC85_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Adenylosuccinate lyase</fullName>
            <shortName evidence="10">ASL</shortName>
            <ecNumber evidence="4 10">4.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">Adenylosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_01945</name>
        <name evidence="13" type="ORF">SAMN05428934_11615</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate</text>
            <dbReference type="Rhea" id="RHEA:23920"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:23921"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(6)-(1,2-dicarboxyethyl)-AMP = AMP + fumarate</text>
            <dbReference type="Rhea" id="RHEA:16853"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:16854"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.2" evidence="4 10"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000016">
        <property type="protein sequence ID" value="SDZ20396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01945"/>
    <dbReference type="EnsemblBacteria" id="AQP43722">
        <property type="protein sequence ID" value="AQP43722"/>
        <property type="gene ID" value="RPIT_01945"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ20396">
        <property type="protein sequence ID" value="SDZ20396"/>
        <property type="gene ID" value="SAMN05428934_11615"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01945"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00132"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00336"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070626">
        <property type="term" value="F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004018">
        <property type="term" value="F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019468">
        <property type="entry name" value="AdenyloSucc_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004769">
        <property type="entry name" value="Pur_lyase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10397">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00998">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00928">
        <property type="entry name" value="purB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADSL_C" evidence="11">
        <location>
            <begin position="369"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP43722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDZ20396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="476" mass="51229" checksum="B729AE52E3B03A76" modified="2017-04-12" version="1">MSVPNVLANRYASTQMRDIWAPEAKIVSERKLWLAVLRAQRDLGVDFGGADPDAVIAAYEAVVEQVDLASIDARERVTRHDVKARIEEFNDLAGHEHIHKGMTSRDLTENIEQLQVLQSLRLVRVRVVAALAQLARLATQYADQPLTGRSHNVAAQLTTLGKRFATAADELLVALGRLDDLIGRYPARGIKGPVGTAQDMLDLLGGDAGRLAELEGRIAAELGFADVLTSTGQVYPRSLDYDAVTALAQIAAAPSNVATTIRLMAGLELVTEGFKEGQVGSSAMPHKMNTRSCERVNGLAVILRGYVSMVGELAGDQWNEGDVSCSVVRRVALPDAFFALDGLFETFLTVLADFGAFPAVIEAELDRYLPFLTTTKVLMAAVRRGVGREVAHEAIKEHAVAVALDLRKGARTNDLLDRLAADERLGLSREELEALVGSPLELAGTAQAQVARIAERVADVVAADPEAASYRPGSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC95</accession>
    <name>A0A1Q2CC95_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Winged helix DNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_02030</name>
        <name evidence="2" type="ORF">SAMN05428934_1013</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY22393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02030"/>
    <dbReference type="EnsemblBacteria" id="AQP43738">
        <property type="protein sequence ID" value="AQP43738"/>
        <property type="gene ID" value="RPIT_02030"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY22393">
        <property type="protein sequence ID" value="SDY22393"/>
        <property type="gene ID" value="SAMN05428934_1013"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02030"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY22393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="194" mass="20716" checksum="8C99FD3C8E4AD0A7" modified="2017-04-12" version="1">MKQAPPTLAPLLRSDLQGELLASLFLHPDDEHTLSDLARLLKAPLTTVHSEVERLAAGGLLEERRVGRARLVRASGTHPLAPPLTELLTLTYGPVAVLPALLRDLPGLERAYVYGSWAARRLGEPGPQPEDVDVLLVGKVSRRAAAKAQGAATAALRQEVNLTILDPGEWERPSSGFASTVKAGPLVPIDLGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC97</accession>
    <name>A0A1Q2CC97_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01965</name>
        <name evidence="3" type="ORF">SAMN05428934_11611</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000016">
        <property type="protein sequence ID" value="SDZ20315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01965"/>
    <dbReference type="EnsemblBacteria" id="AQP43726">
        <property type="protein sequence ID" value="AQP43726"/>
        <property type="gene ID" value="RPIT_01965"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ20315">
        <property type="protein sequence ID" value="SDZ20315"/>
        <property type="gene ID" value="SAMN05428934_11611"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01965"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ20315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="136" mass="13740" checksum="C4EFC33F060AAF79" modified="2017-04-12" version="1">MRLDERGLALSVWTAMALPAFIVAVGIGVDFSGHATAAQEARAIAAEAARAATHEIVIGPAGPVLDVPRARSAALNFANVSGYSAAVTVSGGSTATVRISSTYDTVFLGLIGIHEIGFDVSGSARAVRTLNGTESG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCC1</accession>
    <name>A0A1Q2CCC1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">GTP 3',8-cyclase</fullName>
            <ecNumber evidence="3 12">4.1.99.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Molybdenum cofactor biosynthesis protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">moaA</name>
        <name evidence="14" type="ORF">RPIT_02115</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>AH2 + GTP + S-adenosyl-L-methionine = (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + A + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:49576"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.1.99.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer and homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the radical SAM superfamily. MoaA family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.22" evidence="3 12"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02115"/>
    <dbReference type="EnsemblBacteria" id="AQP43754">
        <property type="protein sequence ID" value="AQP43754"/>
        <property type="gene ID" value="RPIT_02115"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02115"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019008">
        <property type="term" value="C:molybdopterin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061798">
        <property type="term" value="F:GTP 3',8'-cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01225_B">
        <property type="entry name" value="MoaA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013483">
        <property type="entry name" value="MoaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000385">
        <property type="entry name" value="MoaA_NifB_PqqE_Fe-S-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010505">
        <property type="entry name" value="Mob_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06463">
        <property type="entry name" value="Mob_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02666">
        <property type="entry name" value="moaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01305">
        <property type="entry name" value="MOAA_NIFB_PQQE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7 12" id="KW-0408">Iron</keyword>
    <keyword evidence="8 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="13">
        <location>
            <begin position="8"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="267"/>
            <end position="269"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="AQP43754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="335" mass="36576" checksum="9CED4DAE9555025F" modified="2017-04-12" version="1">MVIGLADAHGRVARDLRVSLTDRCNLRCTYCMPAEGLQWLPTEETLSDDEVIRLIRVAVERLGVNRVRFTGGEPLLRPGLERIIAATVALQGSPETALTTNGLGLDKRIDRLKDAGLNRVNISLDSLDPARYAQLTRRDRLGDVLTSIEAVDRAGLRPLKVNSVVMRGTNESDVVPLAEYCLSRGYQLRFIEQMPLGPKHEWSRADMVRAAEILELLGQRFTLTPASEPRGTAPAELWDVAADDGQPGGRVGVIASVTNPFCAACDRTRLTSDGQVRSCLFSRAETDLRALLRGGASDDDIVEAWVGTHLAKPRAHGIDDESFVQPERTMSAIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCG0</accession>
    <name>A0A1Q2CCG0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02200</name>
        <name evidence="3" type="ORF">SAMN05428934_10139</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY23482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02200"/>
    <dbReference type="EnsemblBacteria" id="AQP43770">
        <property type="protein sequence ID" value="AQP43770"/>
        <property type="gene ID" value="RPIT_02200"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY23482">
        <property type="protein sequence ID" value="SDY23482"/>
        <property type="gene ID" value="SAMN05428934_10139"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02200"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY23482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="494" mass="54170" checksum="F98E16233264B266" modified="2017-04-12" version="1">MARSINRLLADFGHTLPTKPSPEQPKLPREFTSAPPWRGKPARGAGWVASRPAVKRYQMTSDQAGVFWPFLTASPLPPTGAPMGTDMSNGATFYVDPHGWVLNDSIPVTNPNIFVFGKPGRGKSAWVKAFLNRMFAFGYQALILGDPKDEYELMCLHFGVEPFAIGPGMPTRLNPLDPGPLASNWGQLNRDEQERRSAVIFGRWLVLLRSLIGSQSIGDRKVAVGPTEEQVLKAVLVELTHTNSDSRELRPIVIPQVWQQLHSPSDALIAELRYPDRHTFLDDTRLLRDAVAQLISGVFAGIFDAPTTVTIDWNAPIQSLSLSRLMPLGDDAVGMALMCLNSWGTAMRQVSGRRRINVRDEVWRQLRLGTGAVSSFDADLRLSRSHGDIEIANAHKPSDYLGAGHAGSQAQQIAKDLLHLGDIKVLFGQDAEVADDLEQLLDLGPVARDIVTGWAMGGKGRALIAVGPRLHKVALTLHPDLELPLTDTNQKLQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCI7</accession>
    <name>A0A1Q2CCI7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_02405</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02405"/>
    <dbReference type="EnsemblBacteria" id="AQP43811">
        <property type="protein sequence ID" value="AQP43811"/>
        <property type="gene ID" value="RPIT_02405"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02405"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010290">
        <property type="entry name" value="TM_effector"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05977">
        <property type="entry name" value="MFS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="340"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="369"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="418" mass="44004" checksum="E6532981C60A6840" modified="2017-04-12" version="1">MASFSVRNYRYFFLGALVSNVGTWVQRIGQDWLVLTELTDGSSAALGIVTALQFLAIPLLAPYAGAVADRVSKRKLLMVTQILLAATAFGLWALVALDVVQLWHVFVFAFLQGVISAFDNPARQSFVSEMVPPGLLSNAVGLNSTSFNGARLVGPGVAGLTIAAFGVGPALLFNALSFLPMIVAIASMNAAELQPAPPVKARGATLDGLKYLTGRADLMIVMVIVFMLGTFGMNFQIYNATMATQVFQKGATEYGMLGTVMAVGTLAGALLAARRAKPSFRTLLLSLAGFAVSSALLTVVPNYTGYSLLLIPAGFFALTVMTTANASVQLATAPEYRGRVMAIYVAIFVGGTPLGAPIIGWIGEVWGPRASIAVGAVATGLTVVGVLAYLVLHDGLRLAVERGWPLRLRVWTAAREAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCN3</accession>
    <name>A0A1Q2CCN3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplK</name>
        <name evidence="12" type="ORF">RPIT_02860</name>
        <name evidence="13" type="ORF">SAMN05428934_101172</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="PTM">
        <text evidence="6 8">One or more lysine residues are methylated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY27330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02860"/>
    <dbReference type="EnsemblBacteria" id="AQP43883">
        <property type="protein sequence ID" value="AQP43883"/>
        <property type="gene ID" value="RPIT_02860"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY27330">
        <property type="protein sequence ID" value="SDY27330"/>
        <property type="gene ID" value="SAMN05428934_101172"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02860"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_L11/L12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_L11/L12_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006519">
        <property type="entry name" value="Ribosomal_L11_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_L11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_L11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_L11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_L11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="PTHR11661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="SSF46906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="SSF54747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01632">
        <property type="entry name" value="L11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0488">Methylation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544424" description="50S ribosomal protein L11" evidence="9">
        <location>
            <begin position="23"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L11_N" evidence="11">
        <location>
            <begin position="11"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L11" evidence="10">
        <location>
            <begin position="73"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP43883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY27330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="142" mass="14980" checksum="635EE6AA7A409A88" modified="2017-04-12" version="1">MPPKKKVAALVKVALQAGSATPAPPVGTALGPHGVNIMEFVKAYNAQTESQRGNVIPVEITIYEDRTFTFITKTPPAAELIKKAAGLKSGSANPLKDKVGKLTKDQVREIATTKLPDLNANDVEAAMKIVEGTARSMGVTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCU2</accession>
    <name>A0A1Q2CCU2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5 7">50S ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplO</name>
        <name evidence="10" type="ORF">RPIT_03185</name>
        <name evidence="11" type="ORF">SAMN05428934_101238</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03185"/>
    <dbReference type="EnsemblBacteria" id="AQP43943">
        <property type="protein sequence ID" value="AQP43943"/>
        <property type="gene ID" value="RPIT_03185"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29465">
        <property type="protein sequence ID" value="SDY29465"/>
        <property type="gene ID" value="SAMN05428934_101238"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03185"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="L18e/L15P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_L15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_L15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_L15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_L18e/L15P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="PTHR12934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="SSF52080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L18e/L15P" evidence="9">
        <location>
            <begin position="28"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP43943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY29465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="146" mass="14976" checksum="3854E2E7989CDEB7" modified="2017-04-12" version="1">MSLKLHHLRPAPGAKTAKTRVGRGEGSKGKTAGRGTKGTGARKNVPQNFEGGQMPIHMRLPKLKGFKNPFRVEYQVVNVGRLAELFPQGGSVSVADLVDAGAVRSGSLVKVLGNGDVDVALDVTADAFSGSAKAKIEGAGGSATLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCU8</accession>
    <name>A0A1Q2CCU8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplF</name>
        <name evidence="7" type="ORF">RPIT_03165</name>
        <name evidence="8" type="ORF">SAMN05428934_101234</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03165"/>
    <dbReference type="EnsemblBacteria" id="AQP43939">
        <property type="protein sequence ID" value="AQP43939"/>
        <property type="gene ID" value="RPIT_03165"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29352">
        <property type="protein sequence ID" value="SDY29352"/>
        <property type="gene ID" value="SAMN05428934_101234"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03165"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01365_B">
        <property type="entry name" value="Ribosomal_L6_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_L6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_L6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_L6_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019906">
        <property type="entry name" value="Ribosomal_L6_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002358">
        <property type="entry name" value="Ribosomal_L6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="PTHR11655"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF14">
        <property type="entry name" value="PTHR11655:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00059">
        <property type="entry name" value="RIBOSOMALL6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="SSF56053"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03654">
        <property type="entry name" value="L6_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00525">
        <property type="entry name" value="RIBOSOMAL_L6_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L6" evidence="6">
        <location>
            <begin position="11"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L6" evidence="6">
        <location>
            <begin position="91"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY29352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="180" mass="19573" checksum="EE8EF3E6A58F84EF" modified="2017-04-12" version="1">MSRIGRLPIAIPSGVDVKLDGRKVDVKGPKGSLSLTVAEPLTIEKNDEGQLEVSRPNDERLSRSLHGLTRTLVNNMITGVTEGYEKKLEIVGVGYRVISKGPQQLEFALGFSHPVVINAPEGITFNVETPTRFSVSGIDKQLVGETAANIRKLRKPEPYKGKGVRYAGEQVRRKAGKAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD08</accession>
    <name>A0A1Q2CD08_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">50S ribosomal protein L24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplX</name>
        <name evidence="6" type="ORF">RPIT_03145</name>
        <name evidence="7" type="ORF">SAMN05428934_101230</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="3">One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03145"/>
    <dbReference type="EnsemblBacteria" id="AQP43935">
        <property type="protein sequence ID" value="AQP43935"/>
        <property type="gene ID" value="RPIT_03145"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29192">
        <property type="protein sequence ID" value="SDY29192"/>
        <property type="gene ID" value="SAMN05428934_101230"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03145"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01326_B">
        <property type="entry name" value="Ribosomal_L24_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="KOW_RPL26/RPL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003256">
        <property type="entry name" value="Ribosomal_L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_L24/26_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12903">
        <property type="entry name" value="PTHR12903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17136">
        <property type="entry name" value="ribosomal_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01079">
        <property type="entry name" value="rplX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KOW" evidence="5">
        <location>
            <begin position="5"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY29192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="123" mass="13659" checksum="DBE457EF15804B56" modified="2017-04-12" version="1">MATLHVKKGDRVKVISGKDRGVVAEVIAVHPETQRVTVQGVNLVKKHRRESQTAQGRRVEGGIINVEAPIHVSNVQPVVKVDGKEVVTRVGYKRVDVTKRRPDGSEYTAQRSVRIARKTGEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD85</accession>
    <name>A0A1Q2CD85_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA polymerase-3 subunit epsilon</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03765</name>
        <name evidence="3" type="ORF">SAMN05428934_101355</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY32935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03765"/>
    <dbReference type="EnsemblBacteria" id="AQP44040">
        <property type="protein sequence ID" value="AQP44040"/>
        <property type="gene ID" value="RPIT_03765"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY32935">
        <property type="protein sequence ID" value="SDY32935"/>
        <property type="gene ID" value="SAMN05428934_101355"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03765"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006054">
        <property type="entry name" value="DnaQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00573">
        <property type="entry name" value="dnaq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="220"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY32935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="602" mass="65435" checksum="97FD473486B8FF63" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDA3</accession>
    <name>A0A1Q2CDA3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">30S ribosomal protein S1</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">SSU ribosomal protein S1P</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_04120</name>
        <name evidence="4" type="ORF">SAMN05428934_101427</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY34894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04120"/>
    <dbReference type="EnsemblBacteria" id="AQP44098">
        <property type="protein sequence ID" value="AQP44098"/>
        <property type="gene ID" value="RPIT_04120"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY34894">
        <property type="protein sequence ID" value="SDY34894"/>
        <property type="gene ID" value="SAMN05428934_101427"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04120"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035104">
        <property type="entry name" value="Ribosomal_protein_S1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724:SF7">
        <property type="entry name" value="PTHR10724:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00681">
        <property type="entry name" value="RIBOSOMALS1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="35"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="122"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="208"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="293"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY34894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="478" mass="52880" checksum="9274CE38AC479BF7" modified="2017-04-12" version="1">MTSSTEASAVAVDDIGTRDDFLAAIDATIISFNDGDIVSGTVVKVDRDEVLLDIGYKTEGVIPSKELSIKHDVDPFDVVQVGDVIEALVQQKEDKEGRLILSKKRAQYERAWGTIEKIKEEDGVVTGSVIEVVKGGLIVDIGLRGFLPASLVEMRRVRDLQPYVGMELEAKIIELDKNRNNVVLSRRAYLEQTQSEVRQTFLTQLQKGQIRKGVVSSIVNFGAFVDLGGVDGLVHVSELSWKHIDHPNEVVEVGTPVTVEVLEVDMDRERVSLSLKATQEDPWQTFARLHQIGQIVPGKVTKLVPFGAFVRVGEGIEGLVHVSELAERHVEIPEQVVAVGDDRMVKVIDIDLERRRVSLSLKQANEGIDVAADDFDPLLYGMQASYDDQGNYIYPEGFDPETNDWKEGFEEQRAAWEAQYAQAHALWEQHKKQVESAESADREAAVEAGTGYVTETSTEGSLATDESLQALRERLAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDB8</accession>
    <name>A0A1Q2CDB8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Biotin transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_04180</name>
        <name evidence="5" type="ORF">SAMN05428934_101440</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the BioY family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY35311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04180"/>
    <dbReference type="EnsemblBacteria" id="AQP44109">
        <property type="protein sequence ID" value="AQP44109"/>
        <property type="gene ID" value="RPIT_04180"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY35311">
        <property type="protein sequence ID" value="SDY35311"/>
        <property type="gene ID" value="SAMN05428934_101440"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04180"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015225">
        <property type="term" value="F:biotin transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003784">
        <property type="entry name" value="BioY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34295">
        <property type="entry name" value="PTHR34295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02632">
        <property type="entry name" value="BioY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016661">
        <property type="entry name" value="BioY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="125"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR016661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY35311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="194" mass="19608" checksum="090608C0D5E60838" modified="2017-04-12" version="1">MSVDTAAPARTLAPADLAYVAVFAALIAALALVPSFLLAGVPFSFAVIGVALAGLALGPWRGAAAVGLYVAAGAAGLPIFSGGRAGLGTLFGPTGGYILSFTLAALVIGAFARLAVRRGITSRSLVWMLAGCVVARLALILPLGVAGLHLWGGMGIREALLVDLPFIPLDLIKFVVAALLAVSVHKAFPRLLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
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    <name>A0A1Q2CDF5_9ACTN</name>
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        </submittedName>
        <submittedName>
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        </submittedName>
    </protein>
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        <name type="scientific">Tessaracoccus flavus</name>
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        <lineage>
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            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY35341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04185"/>
    <dbReference type="EnsemblBacteria" id="AQP44110">
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        <property type="gene ID" value="RPIT_04185"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY35341"/>
        <property type="gene ID" value="SAMN05428934_101441"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04185"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY35341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="231" mass="24719" checksum="8A45870FE093ADD7" modified="2017-04-12" version="1">MISLRAVSVVVPAGGRGERDRALLTDVTLDLPEHRIAVIGANGSGKSTLLRLLNGLRAPTSGTVSVDGLSTVEQASLVRRRVGFVFTDPLAQLLMSTPIEDIELSLRGTVRNRAERARRAQALLDERGLGHLAHQSIYDLSGGERQLVALTSVLAVDPAVLVADEPTTLLDLRNKRALRQVFAGLAQQIIYSTHDLDVAADADRVLVVHDGRIVADGAPDEAIAQYESVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDJ2</accession>
    <name>A0A1Q2CDJ2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 10">Phosphoglycerate kinase</fullName>
            <ecNumber evidence="2 7 10">2.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pgk</name>
        <name evidence="12" type="ORF">RPIT_04215</name>
        <name evidence="13" type="ORF">SAMN05428934_101447</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7 10">
            <text>(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7 11">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 10">Belongs to the phosphoglycerate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.3" evidence="2 7 10"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY35550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04215"/>
    <dbReference type="EnsemblBacteria" id="AQP44115">
        <property type="protein sequence ID" value="AQP44115"/>
        <property type="gene ID" value="RPIT_04215"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY35550">
        <property type="protein sequence ID" value="SDY35550"/>
        <property type="gene ID" value="SAMN05428934_101447"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04215"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004618">
        <property type="term" value="F:phosphoglycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00318">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1260">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00145">
        <property type="entry name" value="Phosphoglyc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001576">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015911">
        <property type="entry name" value="Phosphoglycerate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015824">
        <property type="entry name" value="Phosphoglycerate_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036043">
        <property type="entry name" value="Phosphoglycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406">
        <property type="entry name" value="PTHR11406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00162">
        <property type="entry name" value="PGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000724">
        <property type="entry name" value="Pgk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00477">
        <property type="entry name" value="PHGLYCKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53748">
        <property type="entry name" value="SSF53748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00111">
        <property type="entry name" value="PGLYCERATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7 8">
        <location>
            <begin position="20"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7 8">
        <location>
            <begin position="59"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="332"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <begin position="358"/>
            <end position="361"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP44115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY35550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="405" mass="42323" checksum="4139CE02F3CF2C5D" modified="2017-04-12" version="1">MKALEDLGDLSGKRVLIRCDFNVPLDSDKNITDDGRIKAALPTLNALRDAGARVVVMAHLGRPKGEVNPKYSLAPVAARLGELLGAEVKLADDVVGDSAKAVVESLSDGDVALLENVRYEPAEESKDEAARQELADKYAAFGDIFISDGFGVVHRKQASVYDVAKKLPNAAGKLVAKEVGILKQLTESPERPYVVVLGGAKVADKLAVIDNLLKVADTLIIGGGMAFTFLKAQGHEIGASLLDETNLQTCLDYVEQAKAAGKKLLLPVDVRVAEGMDFDARTVTGDVDVVAASDIPAGKQGLDIGPETEKLYAEAIKGAKTVFWNGPMGVFEIEELSHGTAAVAQALTEVDGLSVVGGGDSAAAVRALGHADDAFGHISTGGGASLEFLEGKELPGLSALEENNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDM0</accession>
    <name>A0A1Q2CDM0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_04385</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44145">
        <property type="protein sequence ID" value="AQP44145"/>
        <property type="gene ID" value="RPIT_04385"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04385"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="140"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="209" mass="22100" checksum="908F66D5CF9A593D" modified="2017-04-12" version="1">MIRVMLVEDDPLAQQAIKTYLSRSADIELVGVAGDGVEALELAPTVNPDVAIVDIHMPRMGGIELTERLTTPPSSIRVVCFTALGDDRVMLQALNAGASGFLLKSDSPGLILHGVRSAFSGDALVSPKLVAAALANRRGQSSPPPDLSATDKELLGLIGRGLSNAEIAQELYLATSTVKTYVSRLLGRLERPNRASLAALAHEWGLVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDQ0</accession>
    <name>A0A1Q2CDQ0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TIGR03083 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04940</name>
        <name evidence="3" type="ORF">SAMN05428934_101594</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY39227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04940"/>
    <dbReference type="EnsemblBacteria" id="AQP44239">
        <property type="protein sequence ID" value="AQP44239"/>
        <property type="gene ID" value="RPIT_04940"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY39227">
        <property type="protein sequence ID" value="SDY39227"/>
        <property type="gene ID" value="SAMN05428934_101594"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04940"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017517">
        <property type="entry name" value="CHP03083_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024344">
        <property type="entry name" value="MDMPI_metal-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11716">
        <property type="entry name" value="MDMPI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03083">
        <property type="entry name" value="TIGR03083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MDMPI_N" evidence="1">
        <location>
            <begin position="11"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY39227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="208" mass="22813" checksum="4AC63BF6A6138BA8" modified="2017-04-12" version="1">MTAEVWAMTHRARQQLADDLATISDDAWRRSSLCQGWNVEHVVAHLTAVASVGSTAWVRSIVLAGFRPSVHNERRLREHLGSTPAETLSRFREVISWTVAPSKDLPAYLGEVLVHSEDIRYPLGIPNPQDVPTATVVADFYATRNFTVQSKTVASRLSLRAEDGAFHSGQGPEVTGPTLALVMTMAGRRSHLDQLSGPGLPRLIERLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDZ0</accession>
    <name>A0A1Q2CDZ0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycosyltransferase involved in cell wall bisynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_05515</name>
        <name evidence="6" type="ORF">SAMN05428934_10350</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY66435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44339">
        <property type="protein sequence ID" value="AQP44339"/>
        <property type="gene ID" value="RPIT_05515"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY66435">
        <property type="protein sequence ID" value="SDY66435"/>
        <property type="gene ID" value="SAMN05428934_10350"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05515"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="4">
        <location>
            <begin position="17"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="3">
        <location>
            <begin position="242"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY66435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="417" mass="45933" checksum="0B14B6E6BD6D56C6" modified="2017-04-12" version="1">MSLRVAILIDDFFPASGGISRSVQTQAEELSHRGVDVTLIVPDRHLEKPRTCRVIECPTLHHDSLPSHLSVLHWSERRAERISRLAQFDVVHSQTDRGAVVLGARVARLQGIPHVHTFHANIAGTHAVLPFASFWGTLAHEVLTTRALAKATRRAPRFHASLPPFSPEIDSHNLFSRMDWRSYGWIAAHVDLVTSPAQYMLDNIERAVGKAIGGVAIPNAYNRTMRDAIGATRRQRGSEGVRFLSIGRLSAEKRLPVLIRAFKEADLPDAELVIVGDGDQRRRLQAEAGSHPRIDFRGHLSDRHALASEFANADALVLSSYRFDVQPMVIVEAALAGLPTVYCDDRLTTGLTAQSALLTEPDHRSLAQGLITMADQQTRARYSAATAELVEKLSPDVMAAAYLDAYAEAIQRKATRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDZ8</accession>
    <name>A0A1Q2CDZ8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integrase core domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05585</name>
        <name evidence="3" type="ORF">SAMN05428934_10364</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY66800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05585"/>
    <dbReference type="EnsemblBacteria" id="AQP44349">
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        <property type="gene ID" value="RPIT_05585"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY66800">
        <property type="protein sequence ID" value="SDY66800"/>
        <property type="gene ID" value="SAMN05428934_10364"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="24"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY66800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="185" mass="21090" checksum="62FF5A6804B9960D" modified="2017-04-12" version="1">MADSVLLSRMFSRVEATMLRATASAMMTSHRRWEGDLIIGSDLRFALVTLDERHTKYTMMRRVCVHDTVTVTDILTSMARELPASLWRSLTWDQGVEMAAHHRFTDETSCTVYFCDPHSPWQRPTNENSNGLKRQYFPKGTDFTRVTDAEVAAAEYELNTRPRKGLDYQTPAERLAKLVGAAPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE40</accession>
    <name>A0A1Q2CE40_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphatidylinositol alpha-mannosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_05705</name>
        <name evidence="5" type="ORF">SAMN05428934_10388</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05705"/>
    <dbReference type="EnsemblBacteria" id="AQP44368">
        <property type="protein sequence ID" value="AQP44368"/>
        <property type="gene ID" value="RPIT_05705"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67342">
        <property type="protein sequence ID" value="SDY67342"/>
        <property type="gene ID" value="SAMN05428934_10388"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05705"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="3">
        <location>
            <begin position="19"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY67342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="342" mass="36001" checksum="2E956971804CAB52" modified="2017-04-12" version="1">MSSDLTVALVCPYSLDTPGGVATHVLGLARWLLREGHRPTVIAPGTREVDAGVPLTLLGRATGFRFNGSVAELAVRPAQARMAARAVRGADIVHVHEPLTPGIGYAASRAAERLVVTHHASFPAGPLNPLARLRSRRLNPRVRIAVSDAAAATARSVTGIDPVIIPNAIELPGMPVERSGRPRVVFLGRLDDPRKGFQVFARVAGLVQEAEFVAMGPGAARSPDVHHLGRVSDAVRLEVLGSADILLAPNLHGESFGLILAEALGCGAAVVASDLPAFRAVADDHRVASFFPVGDARAAATAVRRRLSDPIDPILAWRSAQRFGWDQVGPRVLSAYRAAGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE43</accession>
    <name>A0A1Q2CE43_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glyco_hydro81C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05845</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05845"/>
    <dbReference type="EnsemblBacteria" id="AQP44394">
        <property type="protein sequence ID" value="AQP44394"/>
        <property type="gene ID" value="RPIT_05845"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052861">
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005200">
        <property type="entry name" value="Endo-beta-glucanase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040720">
        <property type="entry name" value="GH81_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31983">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro81C" evidence="2">
        <location>
            <begin position="375"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="755"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="926"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="930"/>
            <end position="972"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="1121" mass="118850" checksum="A386DF1091C0712E" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE46</accession>
    <name>A0A1Q2CE46_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MerR family regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05735</name>
        <name evidence="4" type="ORF">SAMN05428934_10394</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05735"/>
    <dbReference type="EnsemblBacteria" id="AQP44373">
        <property type="protein sequence ID" value="AQP44373"/>
        <property type="gene ID" value="RPIT_05735"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67521">
        <property type="protein sequence ID" value="SDY67521"/>
        <property type="gene ID" value="SAMN05428934_10394"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05735"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
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        <property type="entry name" value="MerR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="2">
        <location>
            <begin position="21"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY67521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="225" mass="25256" checksum="4BD176A0B65ABDED" modified="2017-04-12" version="1">MSGPARTIGRVLEMIRPEFPDISVSKLRYLEAEGLISPDRQQPSGYRRFSQRDVDRLLYVLRAQRDRYLPLKVIREELEALDRGEQPATLVSEPDDAPAKEPRPQPRAASTQGLMTRRQVLTESGLGEAALIQLERLKIIQPRRGSQLYGREAVALADAAKKLAGYGVDLRQFRVLHQAAATEAALVEQALEPYRRRSGPPPEVMADLYRIVLQAHAALLHGQIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CED9</accession>
    <name>A0A1Q2CED9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA repair protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06285</name>
        <name evidence="3" type="ORF">SAMN05428934_103202</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06285"/>
    <dbReference type="EnsemblBacteria" id="AQP44468">
        <property type="protein sequence ID" value="AQP44468"/>
        <property type="gene ID" value="RPIT_06285"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70303">
        <property type="protein sequence ID" value="SDY70303"/>
        <property type="gene ID" value="SAMN05428934_103202"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06285"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007139">
        <property type="entry name" value="DUF349"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03993">
        <property type="entry name" value="DUF349"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="325"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY70303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="414" mass="46435" checksum="A5D916BD8EEE4040" modified="2017-04-12" version="1">MSEQQAPADFGRVDPDGTVYVRVGDTERSVGQIPDSTPEDAMAFYVRRFENLAAEVTLLESRVKAQAMSPEEAKAAIATARTNVDEANAVGDLAALTARLDAIAELLPAQIEARKAQRAEQNAATVAAKEAMVQEAEQLAQGDDWRGGVDRFRTLLDEWKALPRIDRTTDNELWHRFSSARTQYTRRRKAHFSDLNQRRDEAKALKEAIIAEAEPLADSTEWGPTSGAFRDLMQRWKAAGSARRQDDDALWTRFRAIQDKFFDARTAAQSAVDGEQSENLAAKQKLVEQVEADLQGVTDVETAKATHRDFLAKFNEVGHVPRNAMRDLDARVRSISDKVAEMEAAEWRRTDPEARRRAEETVQLFEGQIGRLREDLATAQERGDAKRVKDAEQSIATYESWLEQARETLADFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEG4</accession>
    <name>A0A1Q2CEG4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoribosyl-AMP cyclohydrolase</fullName>
            <shortName evidence="7">PRA-CH</shortName>
            <ecNumber evidence="7">3.5.4.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hisI</name>
        <name evidence="9" type="ORF">RPIT_06460</name>
        <name evidence="10" type="ORF">SAMN05428934_103237</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:20049"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="EC" id="3.5.4.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PRA-CH family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.19" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06460"/>
    <dbReference type="EnsemblBacteria" id="AQP44496">
        <property type="protein sequence ID" value="AQP44496"/>
        <property type="gene ID" value="RPIT_06460"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71256">
        <property type="protein sequence ID" value="SDY71256"/>
        <property type="gene ID" value="SAMN05428934_103237"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06460"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00008"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004635">
        <property type="term" value="F:phosphoribosyl-AMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01021">
        <property type="entry name" value="HisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026660">
        <property type="entry name" value="PRA-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002496">
        <property type="entry name" value="PRib_AMP_CycHydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038019">
        <property type="entry name" value="PRib_AMP_CycHydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01502">
        <property type="entry name" value="PRA-CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141734">
        <property type="entry name" value="SSF141734"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PRA-CH" evidence="8">
        <location>
            <begin position="24"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY71256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="104" mass="11369" checksum="B5235A195A888524" modified="2017-04-12" version="1">MPVYNADGLVPAIAQDADSGEVLMLAWMDEEALRRTLATGRATYWSRSRGEYWVKGETSGNTQEVVSVHEDCDGDTLLVQVRQTGAACHTGNRTCFFTALEPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEI4</accession>
    <name>A0A1Q2CEI4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, CarD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06265</name>
        <name evidence="3" type="ORF">SAMN05428934_103198</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06265"/>
    <dbReference type="EnsemblBacteria" id="AQP44465">
        <property type="protein sequence ID" value="AQP44465"/>
        <property type="gene ID" value="RPIT_06265"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70203">
        <property type="protein sequence ID" value="SDY70203"/>
        <property type="gene ID" value="SAMN05428934_103198"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06265"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036101">
        <property type="entry name" value="CarD-like/TRCF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003711">
        <property type="entry name" value="CarD-like/TRCF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042215">
        <property type="entry name" value="CarD-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02559">
        <property type="entry name" value="CarD_CdnL_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01058">
        <property type="entry name" value="CarD_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141259">
        <property type="entry name" value="SSF141259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CarD_TRCF" evidence="1">
        <location>
            <begin position="2"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY70203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="177" mass="18858" checksum="09771CFCA877D813" modified="2017-04-12" version="1">MQFNQGQTVIHPHHGPATVTGLLSRTIKGKVIEYLELTVCDTGLTVSIPLTKCETVGIRAVAGSSMLADICAVLTAPTGQIENQWARRYKAQRMEAATGDPLRIAAVVRDLIRRREEKGMSLAERDLLKEASAPLLAEIALATGASEEKATVVLHSLVLEGSAEVLAHIDDLGVPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEL6</accession>
    <name>A0A1Q2CEL6_9ACTN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">RPIT_06700</name>
        <name evidence="3" type="ORF">SAMN05428934_110107</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ10152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06700"/>
    <dbReference type="EnsemblBacteria" id="AQP44541">
        <property type="protein sequence ID" value="AQP44541"/>
        <property type="gene ID" value="RPIT_06700"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ10152">
        <property type="protein sequence ID" value="SDZ10152"/>
        <property type="gene ID" value="SAMN05428934_110107"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06700"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ10152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="74" mass="7836" checksum="E0F51494EB166082" modified="2017-04-12" version="1">MGSTPGNESEESGTSRSEDGMVVLSYLLSGIILYGGLGWAGDHFLKTSWLLPVGLILGLVTSIYLIIKRYGSGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEM0</accession>
    <name>A0A1Q2CEM0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptide ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Peptide/nickel transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_06845</name>
        <name evidence="7" type="ORF">SAMN05428934_11077</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06845"/>
    <dbReference type="EnsemblBacteria" id="AQP44564">
        <property type="protein sequence ID" value="AQP44564"/>
        <property type="gene ID" value="RPIT_06845"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09640">
        <property type="protein sequence ID" value="SDZ09640"/>
        <property type="gene ID" value="SAMN05428934_11077"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06845"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="67"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="65"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ09640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="269" mass="28051" checksum="76F11A8E63D7004A" modified="2017-04-12" version="1">MRRATLYFGLVLIGIVVLLAGVGLVWTPFDPAAVTSSRLLPPGWPHVLGTDGFGADILSRLMSGAKIILLVGVASVAGAALIGVPLGIFAGMARGWAGEIPARLSDILYGFPALLLAILLAAALGGSTWTAMLAIAISTIPAFVRIARAATLQVMSQGYVEAARLSGTPRLAIARRHVLPNIAPVLGVQASVSFGIAILAEAGLSYLGLGSGPQQPTWGRMLREAQDHLFSDPLLALWPGLAIAIATMGFNLLGDGLRDLLDPRLREIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEZ4</accession>
    <name>A0A1Q2CEZ4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">RPIT_07585</name>
        <name evidence="2" type="ORF">SAMN05428934_1223</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
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    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000022">
        <property type="protein sequence ID" value="SDZ23080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44684">
        <property type="protein sequence ID" value="AQP44684"/>
        <property type="gene ID" value="RPIT_07585"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ23080">
        <property type="protein sequence ID" value="SDZ23080"/>
        <property type="gene ID" value="SAMN05428934_1223"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07585"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ23080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="385" mass="42081" checksum="A71D0B7188312BE9" modified="2017-04-12" version="1">MTKWQCPFCGGLGKPTDEHVWAKWLRQTQGARKLLQDQNGQRMPLEWSSMQINEEGRYESSSERQRDWATLLPHVTVKVCKDCNNGWMSELERRAQSIIGPLVLEGRRIWLGADEQMALAQWAIKVFMAYALTLGPLDNPFPESAYGNLIEGRLPAGCRIWLAHFDSRFAQVGLAIKATALLKSFDPIRDQNNAALGYLAAGGLVFLLVLVPEALEELGAAMSPPMAAENGTAFLISQPTGLIALTHPALDEGDMALVMSWLESMRLVRMPAAEGLTPADFELLQGLFEGGADPAAIRTLVPEGLDPAFLEQAANHEHDTMAEASRYREAGDLIGAGLLLTHQGRQHFQGGDFEGASRLLIAAIESPGSGLDRDAEAAYRVGQCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF52</accession>
    <name>A0A1Q2CF52_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07875</name>
        <name evidence="2" type="ORF">SAMN05428934_11315</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07875"/>
    <dbReference type="EnsemblBacteria" id="AQP44733">
        <property type="protein sequence ID" value="AQP44733"/>
        <property type="gene ID" value="RPIT_07875"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16298">
        <property type="protein sequence ID" value="SDZ16298"/>
        <property type="gene ID" value="SAMN05428934_11315"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07875"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ16298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="154" mass="16143" checksum="90E49B28E01E129B" modified="2017-04-12" version="1">MNATSPAAETPDNINRQTQRELYGEPIADIVGRITSALGLTQGRLAEVIGLSAPMLSQLVSARRVKIGNPAVLARLQSLADLAVGPALSLEEREARLAAIHDEQPTMSTMRDAGAVHALRAAAPSEELQRLAQQTTAPELAALLRLAAGPSSHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF55</accession>
    <name>A0A1Q2CF55_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">3-isopropylmalate dehydratase small subunit</fullName>
            <ecNumber evidence="10">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Alpha-IPM isomerase</fullName>
            <shortName evidence="10">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">leuD</name>
        <name evidence="12" type="ORF">RPIT_07900</name>
        <name evidence="13" type="ORF">SAMN05428934_11320</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 10">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the LeuD family. LeuD type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="10"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07900"/>
    <dbReference type="EnsemblBacteria" id="AQP44738">
        <property type="protein sequence ID" value="AQP44738"/>
        <property type="gene ID" value="RPIT_07900"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16395">
        <property type="protein sequence ID" value="SDZ16395"/>
        <property type="gene ID" value="SAMN05428934_11320"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07900"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009316">
        <property type="term" value="C:3-isopropylmalate dehydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01577">
        <property type="entry name" value="IPMI_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01031">
        <property type="entry name" value="LeuD_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004431">
        <property type="entry name" value="3-IsopropMal_deHydase_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033940">
        <property type="entry name" value="IPMI_Swivel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00171">
        <property type="entry name" value="leuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase_C" evidence="11">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP44738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDZ16395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="201" mass="22284" checksum="9E56253135787058" modified="2017-04-12" version="1">MEPFVRHTGIAVPLERSNVDTDQIIPAVYLKRITRTGFEDGLFAAWRNDPEFVLNREPFTQGTILIPGPDFGTGSSREHAVWALQNYGFKAVIGTRFGDIFRSNSGKAGLLVALVSEADRDLLWQAIEADPNVETTVDLESQTITRGDLQVSFDIDDYTKHRLLNGLDDISLTLQQDEAISTYEASRPSFKPKTLPAKTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF66</accession>
    <name>A0A1Q2CF66_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_08065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08065"/>
    <dbReference type="EnsemblBacteria" id="AQP44764">
        <property type="protein sequence ID" value="AQP44764"/>
        <property type="gene ID" value="RPIT_08065"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08065"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="150" mass="17075" checksum="26B7185108932027" modified="2017-04-12" version="1">MTELPRRDPESGLPFAEVTRRIEWSDTDASGHHHNSVVWRFVESCEAQLFRELGYLESYFNGAPRVHQTVDYENKLYFGQNTTTKVGLTKVGNSSLSFWFELWGEEQGDRPRRRAASGRFVTVHVAQGTETAIPWPDDLRQALLGTATSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF73</accession>
    <name>A0A1Q2CF73_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CTP synthase</fullName>
            <ecNumber evidence="9">6.3.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cytidine 5'-triphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Cytidine triphosphate synthetase</fullName>
            <shortName evidence="9">CTP synthetase</shortName>
            <shortName evidence="9">CTPS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">UTP--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pyrG</name>
        <name evidence="12" type="ORF">RPIT_08080</name>
        <name evidence="13" type="ORF">SAMN05428934_11356</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + H2O + L-glutamine + UTP = ADP + CTP + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + NH4(+) + UTP = ADP + CTP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16597"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="9">CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the CTP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ17076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08080"/>
    <dbReference type="EnsemblBacteria" id="AQP44766">
        <property type="protein sequence ID" value="AQP44766"/>
        <property type="gene ID" value="RPIT_08080"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ17076">
        <property type="protein sequence ID" value="SDZ17076"/>
        <property type="gene ID" value="SAMN05428934_11356"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08080"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
    </reference>
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            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
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            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
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            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 13">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="13"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08260"/>
    <dbReference type="EnsemblBacteria" id="AQP44792">
        <property type="protein sequence ID" value="AQP44792"/>
        <property type="gene ID" value="RPIT_08260"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19470">
        <property type="protein sequence ID" value="SDZ19470"/>
        <property type="gene ID" value="SAMN05428934_11523"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08260"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00281">
        <property type="entry name" value="Phe_tRNA_synth_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004529">
        <property type="entry name" value="Phe-tRNA-synth_IIc_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004530">
        <property type="entry name" value="Phe-tRNA-synth_IIc_mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004188">
        <property type="entry name" value="Phe-tRNA_ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022911">
        <property type="entry name" value="Phe_tRNA_ligase_alpha1_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF41">
        <property type="entry name" value="PTHR11538:SF41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02912">
        <property type="entry name" value="Phe_tRNA-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00468">
        <property type="entry name" value="pheS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 13 16" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="10 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="14">
        <location>
            <begin position="135"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="AQP44792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="SDZ19470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="369" mass="40175" checksum="867178EFDA20009B" modified="2017-04-12" version="1">MSGPNDNFDPKQVAALDASAIERYVHDALEAIAAATSTAELKRARHDHAGDTSPLALANREIGALPPQARKEAGRRVGEARGTVSRALSERQDEVAAAELEASLVVERVDMTLPVTLRPQGALHPVTTLIDEMIDVFVAMGWEVADGPELEAEWYNFDALNLGPDHPARALQDTLWVDPPSGGKLMRTQTSPVQARALLEYGVPLYVISPGKVFRADEYDATHLPVFHQLEGLVVDRGISMADLRGTLDHLARAMFGDVRTRMRPHYFPFTEPSAEVDLECFVCHGASVGNPDAPCRTCKSEGWIEWGGCGVVNPRVLRACGVDPDVYSGFAFGMGVDRTVMFRTGAPDLRDFVEGDIRFSRSILGGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFB3</accession>
    <name>A0A1Q2CFB3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_08375</name>
        <name evidence="2" type="ORF">SAMN05428934_1331</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000033">
        <property type="protein sequence ID" value="SDZ24555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44809">
        <property type="protein sequence ID" value="AQP44809"/>
        <property type="gene ID" value="RPIT_08375"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ24555">
        <property type="protein sequence ID" value="SDZ24555"/>
        <property type="gene ID" value="SAMN05428934_1331"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08375"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ24555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="105" mass="11353" checksum="847F7652A85D50D4" modified="2017-04-12" version="1">MGRPPVIPVEKKTRIVLSILAGEMTIAEAARREKVSEQSIGRWKADFLEAGKAGLAAGRSGPSTREQQLEAEVTELTQALGEAAVEIRVWKKSAKGRLGPSRTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFF9</accession>
    <name>A0A1Q2CFF9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08225</name>
        <name evidence="3" type="ORF">SAMN05428934_11530</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44785">
        <property type="protein sequence ID" value="AQP44785"/>
        <property type="gene ID" value="RPIT_08225"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19618">
        <property type="protein sequence ID" value="SDZ19618"/>
        <property type="gene ID" value="SAMN05428934_11530"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08225"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ19618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="295" mass="30689" checksum="2C9AFCBA6FDCAA5D" modified="2017-04-12" version="1">MSVARSILSLIVLLAAMSLSLLGLGSHWVDRVARTPGPLADIVGPLEPDGQIARAIKAELRSAVLAQLPDLSAAPELGAQVDGLITRALDDALTSDEAQRAWRSSLDLTRAGLVGSLDAVRRDGADAPTVWFELSPFIALAQQRAEAAATEPVRAQLALVGVPDTVAVPLGRPDAGEAQVAADALGLAGNWRIYYAGALVLAVLGLVIGSRRGRWWAWLMATAAGPAALFLAARALEFVRVPVADSIASSLQARIITGSTASISAWISTAYYVGFAAFALGVIGLIVASARRDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFG8</accession>
    <name>A0A1Q2CFG8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Dihydrofolate synthase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Dihydrofolate synthase / folylpolyglutamate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_08775</name>
        <name evidence="8" type="ORF">SAMN05428934_10765</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08775"/>
    <dbReference type="EnsemblBacteria" id="AQP44872">
        <property type="protein sequence ID" value="AQP44872"/>
        <property type="gene ID" value="RPIT_08775"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97632">
        <property type="protein sequence ID" value="SDY97632"/>
        <property type="gene ID" value="SAMN05428934_10765"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08775"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="PTHR11136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001563">
        <property type="entry name" value="Folylpolyglu_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01011">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="6">
        <location>
            <begin position="136"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="5">
        <location>
            <begin position="301"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY97632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="443" mass="46628" checksum="736093705E1CA819" modified="2017-04-12" version="1">MTTSPHAELTAALTSRWPEHRVAPSLSRISALMELLGDPQRSFPVIQVAGTNGKGSTAIMIETLLRAAGLRTGRFASPHLSDVRERITIDGEPVSEERFDEVWRDVEPYVAMVDEQLHDGVAMTFFEVITGMAYAAFADAPVDVAVMEVGLGGRWDATSVADAQVAVVAPIGLDHTHILGDTIEQIAGEKAGIIKPGSVAVLAGQDPAAAKVLLERAVGVGAKVRAEGPDFALLERRVAVGGQLLRIDTAGGPVGDVFLPLFGEHMARNASLAVAAVEAFLGSQPLNPEIIVEAMASVEAPARLEIVRTSPTVVVDTAHNAQAARATVDAVAESFDFQPTIGVVAMMQDKDAEEVLGIFSEQMDQVVVTQVRNSPRARPVAELAELAESVWSPGNVHRADTMAEALELATMLADTASAHAGVLVAGSVIAAGEARDLLKRDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFH4</accession>
    <name>A0A1Q2CFH4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0371 protein RPIT_08745</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0371 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44866">
        <property type="protein sequence ID" value="AQP44866"/>
        <property type="gene ID" value="RPIT_08745"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08745"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01567">
        <property type="entry name" value="UPF0371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014999">
        <property type="entry name" value="UPF0371"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08903">
        <property type="entry name" value="DUF1846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033132">
        <property type="entry name" value="DUF1846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="499" mass="55792" checksum="EF3F35E51A08ADD9" modified="2017-04-12" version="1">MGEQRKIGFDRDKYLALQSQHIDERRKRFGGKLYLEFGGKLFDDHHAARVLPGFTPDNKIQMLRTIADEVEVVIAISAHDLASNKVRADLGIPYDSDVLRLIDEFRSYGLYVGSVVITQMTDEHRQARAFKRKLERLGLKVYRHYPIKGYPNDVALIVSDQGYGRNDYIETSRDLVVVTAPGPGSGKMATCLSQLYHDHRRGIPSGYAKYETFPIWNLPLDHPVNLAYEAATADLDDVNMIDPYHLAAYGEQVVNYNRDVEIFPVLNLLFERLFGSSPYRSPTDMGVNMAGVCISDDEVCREASKQEVIRRYYKALVEERRDELEPTQSSRMALTMSQLGITKEDRPVVGPALAVEGKTKAPAAAIQLADGRIVTGKTSPLLGASSAMLLDALKSLAGIDDAVRLLDPETIEPIQTLKTTHLGSANPRLHTDEVLIALSVSARFDENARRALAELRHLRGCDVHTTVILGPVDEAIFRNLGVQVTSEPVYQTKKLYRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFI1</accession>
    <name>A0A1Q2CFI1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08770"/>
    <dbReference type="EnsemblBacteria" id="AQP44871">
        <property type="protein sequence ID" value="AQP44871"/>
        <property type="gene ID" value="RPIT_08770"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08770"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025327">
        <property type="entry name" value="DUF4233"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14017">
        <property type="entry name" value="DUF4233"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="132" mass="13988" checksum="966D3757F8BE843C" modified="2017-04-12" version="1">MSHRRGGGPGPAQEGRRVTLNPTNPMRAAAASVLLFEIIIVWLAYIGMIQVSGTNLALAAGACAAVTLGCIAALAGLRRRWGYIVGWGVQIGCIALGLLTAWMFAMGIIFALIWVTCIVLGRRIETHQGEAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFM7</accession>
    <name>A0A1Q2CFM7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09010</name>
        <name evidence="4" type="ORF">SAMN05428934_107115</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44914">
        <property type="protein sequence ID" value="AQP44914"/>
        <property type="gene ID" value="RPIT_09010"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98537">
        <property type="protein sequence ID" value="SDY98537"/>
        <property type="gene ID" value="SAMN05428934_107115"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09010"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY98537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="291" mass="31632" checksum="54BC2E99C998B8D0" modified="2017-04-12" version="1">MPDRIPQLDHLADQAKEVPMLPPSEIRRRGNRRRLIRHTAVGAVIAVFLGAAGFTVWQSSLLDSVREQPQWATTMSASPTPTPSPSASPSEEPQQPTMTPSPQPTAAPPVLPDPPTWDNVPDAQIMYPYDPSVIAETRDYEGLRDTPTGLCDPGSYGDPSTVLVREFLSVDQMGAVAIVFGYPDEASAQAGYALLEDAARYCPTAIGDPYYVSFEDGEGSSAYISSIHPADDPDEGLFNDTHLIQDGERVLWRVNTYLGQDQNCSVLPNDDAMQCESVKSADAALERLRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFN1</accession>
    <name>A0A1Q2CFN1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09095"/>
    <dbReference type="EnsemblBacteria" id="AQP44926">
        <property type="protein sequence ID" value="AQP44926"/>
        <property type="gene ID" value="RPIT_09095"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09095"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="452" mass="47618" checksum="4BE7DAFD628781B3" modified="2017-04-12" version="1">MAAVDDDTIAYWQHADADRWQSETPTLVSEAATRIAARSDRAFFTNPADARASWALSVGAAAAARAIAYSNKPLVHDGPATIPAGHADPDLTRLVIRDAVGCRVRTVEGRVLFDLSSGLYNTPLGHRHPAPAVGFLTQATSVAATNPFVATTPVAEHVADRLRRALCLNEWSVVFAGSGSEAMETAMRFAVAAAGRIVNVRPGEFHGITAAAAALSSHHTVHYPLRPIMDVRYTPISDWKERGVGVIEPAGVMSGQPPITEADRSQLSSFRRRGGVVVVDEVLSGLGRTMWPSLTTALRIPADIVVLGKGLANGIVPISAVLIAPEVLARVTGTGGLDHGHTHSNHAASLGAALGCLESLEAHKHDPDRLRAALDAAGVANTTIGWLASVKLTESSRATTTAALLDAGLMCHLPTMVDPVERLIVAPPLTTSDEDLADMAQRLADVQRVLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFP5</accession>
    <name>A0A1Q2CFP5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GTP-binding protein EngB required for normal cell division</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_09025</name>
        <name evidence="6" type="ORF">SAMN05428934_107118</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09025"/>
    <dbReference type="EnsemblBacteria" id="AQP44917">
        <property type="protein sequence ID" value="AQP44917"/>
        <property type="gene ID" value="RPIT_09025"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98605">
        <property type="protein sequence ID" value="SDY98605"/>
        <property type="gene ID" value="SAMN05428934_107118"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09025"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005662">
        <property type="entry name" value="GTP-bd_Era"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698">
        <property type="entry name" value="PTHR42698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="419"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="463"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="G" evidence="4">
        <location>
            <begin position="49"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="324"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="489"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY98605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="533" mass="56736" checksum="1CD7040D0D86E15B" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFR7</accession>
    <name>A0A1Q2CFR7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09325</name>
        <name evidence="3" type="ORF">SAMN05428934_102444</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY60953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44961">
        <property type="protein sequence ID" value="AQP44961"/>
        <property type="gene ID" value="RPIT_09325"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY60953">
        <property type="protein sequence ID" value="SDY60953"/>
        <property type="gene ID" value="SAMN05428934_102444"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09325"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY60953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="96" mass="10756" checksum="2F0E88BDDC84E8E5" modified="2017-04-12" version="1">MAVKEYRDGRERRTAAMLPEVFDQVRKIAHYENRSLAYQLGMFVADGVAQWVEKNGPVRTAPSPEKRNAPISWRRPGALQGSMKGATSCQHLAGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFT7</accession>
    <name>A0A1Q2CFT7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09445</name>
        <name evidence="3" type="ORF">SAMN05428934_102417</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY60190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44981">
        <property type="protein sequence ID" value="AQP44981"/>
        <property type="gene ID" value="RPIT_09445"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY60190">
        <property type="protein sequence ID" value="SDY60190"/>
        <property type="gene ID" value="SAMN05428934_102417"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09445"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY60190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="179" mass="20010" checksum="C45F77B083008630" modified="2017-04-12" version="1">MTGDDTPCREDLHKHLDFIQAVVTRMSAASTSTKSWLLPVVTATYGYGMTQNAWSVIALGLGAVLLFMFLDAHYLDREKAYRALYDAVARNKGIPLFSLDPREVQRCGQVPENQHDITADEVDDQATGAVDTPEKGPRFQFLNDWKPDTSVWKSWAITPFYGSLLLVGLILLVRVCLMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG01</accession>
    <name>A0A1Q2CG01_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09830"/>
    <dbReference type="EnsemblBacteria" id="AQP45048">
        <property type="protein sequence ID" value="AQP45048"/>
        <property type="gene ID" value="RPIT_09830"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09830"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026898">
        <property type="entry name" value="PrsW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36844">
        <property type="entry name" value="PTHR36844"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13367">
        <property type="entry name" value="PrsW-protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="397" mass="42967" checksum="07C0F1E4508F4334" modified="2017-04-12" version="1">MTDAPPTRPHPTLDAAVQHKRQALVLPLLFIAVGAIGTALGMLVVLHRPLPNTLAAVVPFTVILLIGVWFLNWLDRWEPEPPRFAIGAFLWGAGVSALISGVVNSLYLGITQDLSATAMYSAPLIEESTKALFLYVVLLSTRRGRAEFNSLTDALVYGGLVGLGFAWIEHIGYALSVETLEESTPIIIGRIVLTSYLHPVLTMIVAVGIWAGVTSRGAGRRLRPFMAWLVAVGLHFLHNGSYELFGPWGIAIAAVAEFVAFVTLIVLGVRSRRAERAEIVRQLPAMVHFGWITPLEAGWLADAPARKRMLGSAGAQRRTLHDFIQNTTELALLRGRLDAMPPGSHPIELLQLHGELADLVAHQRPVVQGILARSNGWHTLEARPGPSWGAPTGDGGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG39</accession>
    <name>A0A1Q2CG39_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thump_like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10005"/>
    <dbReference type="EnsemblBacteria" id="AQP45081">
        <property type="protein sequence ID" value="AQP45081"/>
        <property type="gene ID" value="RPIT_10005"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10005"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041497">
        <property type="entry name" value="Thump-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18096">
        <property type="entry name" value="Thump_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thump_like" evidence="1">
        <location>
            <begin position="315"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="387" mass="41629" checksum="3C4B7907C6F595C3" modified="2017-04-12" version="1">MTNAGPGWATLGPEHGRALVAAMAEPDPSSLAAAQHLRASFGPELSAWALGQAALRKRAKAKFHRAESMLFTPTGLEQASRERVSRWRAERFRAAGVSAVWDLGCGIGADAMAFAEQRLRVSAVDADPATVAVASHNLRLVGAEPARLGRAEDAPVAPDAAVFLDPARRTARGRTWNVEDFTPPWPLVLDHLASDRFVSVKLGPGLPKELIPANVQACWVSDAGDVVEVSLWNRHPAGSCAVLLREGHPPLTLSRVKDPEAAEVGPLGRFLYEPDGAVIRAGLVADVADANGMWFLDPHVAYLSSDDPVDTAYATRFEVEAVVDYSLRAMRSYVREHGIGTLEIKKRALDVDPAALRRQLKPRGSASATVILARTTEGARAVFARRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG44</accession>
    <name>A0A1Q2CG44_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_10050</name>
        <name evidence="9" type="ORF">SAMN05428934_102296</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TsaE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10050"/>
    <dbReference type="EnsemblBacteria" id="AQP45089">
        <property type="protein sequence ID" value="AQP45089"/>
        <property type="gene ID" value="RPIT_10050"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56843">
        <property type="protein sequence ID" value="SDY56843"/>
        <property type="gene ID" value="SAMN05428934_102296"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10050"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003442">
        <property type="entry name" value="T6A_TsaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02367">
        <property type="entry name" value="TsaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00150">
        <property type="entry name" value="T6A_YjeE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="7">
        <location>
            <begin position="4"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY56843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="304" mass="32136" checksum="156A269DE34FDA4D" modified="2017-04-12" version="1">MEEPTLRVADRSDAPELLRVIRAAFSARRRVDPPAEALADDLPDIERALDAGVGVVAELGGVIVAGLLIDISGAVATLRRVSVVPEVSGHGVARALVGGALTLAADLGARRAELFAREEFPELIEWWRDHGFVVLGPAPHGVRMGRDLPVIRDVPTADDMLDLGRRLSRILRKGDLIVATGDLGAGKTTLTQGIGEGLGVAGPVTSPTFVLSRVHASLGGGPDLVHVDAYRLGDASELADIDLDETLAQSVTIVEWGSGLAEWLADDRLEIDIVRGQAGDTRTVYLTGIGPRWAGALDNLREQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG56</accession>
    <name>A0A1Q2CG56_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">BMP family ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_09785</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BMP lipoprotein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09785"/>
    <dbReference type="EnsemblBacteria" id="AQP45040">
        <property type="protein sequence ID" value="AQP45040"/>
        <property type="gene ID" value="RPIT_09785"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09785"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003760">
        <property type="entry name" value="PnrA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02608">
        <property type="entry name" value="Bmp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Bmp" evidence="3">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Bmp" evidence="3">
        <location>
            <begin position="176"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="316" mass="32961" checksum="AD1CA1C6BDE3289A" modified="2017-04-12" version="1">MVSDAGGFDDKSFNETAHNGMMRAKDELGIQTNQIESNAEGEYAGNVQAMIDANCNIVITVGFALATATEAAAKQNPDVDFAIVDFGSFEGVDNAKGLLFNAAEPSFLAGYLAAGMSETGTVGTFGGAKYPTVTIFMDGFHQGVQYYNEQKGASVQLIGWDEAAQDGQFIGGNNPFGDIPGGKNTASTLIAQGADIILPVAGPAGLGALQAAQESGGKVKGIWVDSDGFESTEYGEHIITSVEKGMDVAVFEAIQASLDGNFDSEPYVGTLENGGVSLSEFHDFDAEVPEELKSELEQIKADIVAGTIEITSPSQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG74</accession>
    <name>A0A1Q2CG74_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA uridine(34) hydroxylase</fullName>
            <ecNumber evidence="1">1.14.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA hydroxylation protein O</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trhO</name>
        <name evidence="3" type="ORF">RPIT_10210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AH2 + O2 + uridine(34) in tRNA = 5-hydroxyuridine(34) in tRNA + A + H2O</text>
            <dbReference type="Rhea" id="RHEA:64224"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="Rhea" id="RHEA-COMP:13381"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:136877"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TrhO family.</text>
    </comment>
    <dbReference type="EC" id="1.14.-.-" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10210"/>
    <dbReference type="EnsemblBacteria" id="AQP45118">
        <property type="protein sequence ID" value="AQP45118"/>
        <property type="gene ID" value="RPIT_10210"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10210"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00469">
        <property type="entry name" value="TrhO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022111">
        <property type="entry name" value="Rhodanese_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020936">
        <property type="entry name" value="TrhO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040503">
        <property type="entry name" value="TRHO_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268">
        <property type="entry name" value="PTHR43268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12368">
        <property type="entry name" value="Rhodanese_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17773">
        <property type="entry name" value="UPF0176_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="136"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="300" mass="32761" checksum="D1901DE8998E5624" modified="2017-04-12" version="1">MSVAKILLFYRFVPLADPEAVKLWQLELCTRLKLRGRVIVAPHGINATLGGELDACKAYLRATKQYGPFRELDEKWSEGTSLDDEGRSLDFPRLSVKTRPELVAFGTPGDVVVGPEGVVGGGERLTPEQVDDLASSNAEVVFFDGRNRVEAEVGRFDGAVVPDVDNTHDFLAELDSGKYDHLKDRPIVTYCTGGVRCEVLSKLMKDRGFAEVYQLHGGVARYLERFGSSSLWKGDLAVFDGREVMQVPGSTPIGTCHACGAPTSRLQNCADLSCRSRLVTCDRCGERPVDCNAHGPAPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGA6</accession>
    <name>A0A1Q2CGA6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HNH endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_10395</name>
        <name evidence="4" type="ORF">SAMN05428934_102226</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY54930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45152">
        <property type="protein sequence ID" value="AQP45152"/>
        <property type="gene ID" value="RPIT_10395"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY54930">
        <property type="protein sequence ID" value="SDY54930"/>
        <property type="gene ID" value="SAMN05428934_102226"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10395"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003870">
        <property type="entry name" value="DUF222"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02720">
        <property type="entry name" value="DUF222"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="2">
        <location>
            <begin position="329"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY54930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="470" mass="50990" checksum="DEF15BA29F795A2A" modified="2017-04-12" version="1">MSEIRELGQRYIAALWDAAHTVGSDPTAGHRLAGLVDAVTEAESQLAGFRLHLLREARLTGADIVVDQVRGSVRTTPAQATATIKLATDLADRFPIIAAALTDGAISLAQADAIVTGLRKLPGGLTRADLARCQTTILEYADTLGPTELRVLASRLVEVIDPDRADADDAARLAADERAARRNRWLRLTPDHHGSTRITGQLPVADAAVLSAQLEALMPPASAYSDAALTPTPDMRRADALIALTHTAATTGGLPAHGGDRPRVHFTLDYHTLLTGLGKADLLTTTTHDRLTAGEARRLACDAGIIPIVLGGRSQPIDVGREQRTFPRAVRAALIERDRGCVFPGCTATPAQCEAHHIIPWWNQGPTSVHNGVLLCPYHHRLVEPDPLQSEQSQWQVHLDPVTDMPWFTPPRHIDPRRRPRQHTRHRLHHITPAETAPARAPDPPGSPDPDGPDLDDLINRTAHVWHPDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGA8</accession>
    <name>A0A1Q2CGA8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-2 type transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10350</name>
        <name evidence="3" type="ORF">SAMN05428934_102235</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10350"/>
    <dbReference type="EnsemblBacteria" id="AQP45144">
        <property type="protein sequence ID" value="AQP45144"/>
        <property type="gene ID" value="RPIT_10350"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55183">
        <property type="protein sequence ID" value="SDY55183"/>
        <property type="gene ID" value="SAMN05428934_102235"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10350"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY55183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="243" mass="25363" checksum="7AE4CA207D25BCB2" modified="2017-04-12" version="1">MNRIFIATELARLRRDPVLLLIVVVLPVFFFLGASVAIPDTLDENTRTSVRDGVMIGLACYGAATAASTITGQTALERVHGWARQVGLTPLATWRFLAVKATVALVAVVATVGVMFTVAAISGILASPLAWLAAGAVVLVGSVTWALYGLVVGLAFRSQSALAASAAGLVLLALGGGVFVPLPEHLVWIARWTPMYGQVELARLALAGGDASAALWPLANWLGWTGVLAGLAAWLVGRSRRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGB9</accession>
    <name>A0A1Q2CGB9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Addiction module antidote protein, HigA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10440"/>
    <dbReference type="EnsemblBacteria" id="AQP45161">
        <property type="protein sequence ID" value="AQP45161"/>
        <property type="gene ID" value="RPIT_10440"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10440"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013430">
        <property type="entry name" value="Toxin_antidote_HigA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36924">
        <property type="entry name" value="PTHR36924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02607">
        <property type="entry name" value="antidote_HigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="25"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="100" mass="10973" checksum="BF0D3BB1F1E8723E" modified="2017-04-12" version="1">MTTTEKIAPIHPGEVLMEDFIEGFGITQNKLAVSIGVPPRRINEIVHGKRGITADTALRLGKLFGTTAQFWLNLQTLYDLDLAEDRAAEQIDAIVPLQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGG2</accession>
    <name>A0A1Q2CGG2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10675</name>
        <name evidence="3" type="ORF">SAMN05428934_102170</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY53233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10675"/>
    <dbReference type="EnsemblBacteria" id="AQP45201">
        <property type="protein sequence ID" value="AQP45201"/>
        <property type="gene ID" value="RPIT_10675"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY53233">
        <property type="protein sequence ID" value="SDY53233"/>
        <property type="gene ID" value="SAMN05428934_102170"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10675"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY53233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="160" mass="17054" checksum="FD855C4CF5C7A1CD" modified="2017-04-12" version="1">MAHAGRGDAGDTAGLPLFLILIAGIGRAFLLQGIHEEWWFRGFAFRGYRERPVLVLAATTVFFTLLHLVSSGGQQSASELFLYLALPLGMGFWAGVERLRTDTVWGAVGIHGGIHVGLVGAQLLGWEMGPAAWITIGLALCAAAMVRLVTAPKNQRQSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGG5</accession>
    <name>A0A1Q2CGG5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Type-5 uracil-DNA glycosylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_10380</name>
        <name evidence="13" type="ORF">SAMN05428934_102229</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10380"/>
    <dbReference type="EnsemblBacteria" id="AQP45150">
        <property type="protein sequence ID" value="AQP45150"/>
        <property type="gene ID" value="RPIT_10380"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55014">
        <property type="protein sequence ID" value="SDY55014"/>
        <property type="gene ID" value="SAMN05428934_102229"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10380"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033958">
        <property type="term" value="F:DNA-deoxyinosine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10031">
        <property type="entry name" value="UDG-F5_TTUDGB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044147">
        <property type="entry name" value="UdgB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="11">
        <location>
            <begin position="93"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP45150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY55014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="278" mass="29722" checksum="4D5F119C81531A83" modified="2017-04-12" version="1">MSALLPHPATGARFPSPVPPGRGWPGDPAEPSTSAADTPGEVRNLADGATLPQLDARVSVCRACPRLVEWREQVALTKRLAFADEPYWGRPAPGWGDPDARALIVGLAPAAHGANRTGRIFTGDRSGDWLYAALHRAEFANQPTSVHAADGLRLTGVRITAPVHCAPPDNKPSTDEKATCSPWLDRELAILAPQLSSILALGGIAWTETLKAARRLGWAVPRPAPRFGHGAESILTTSHGPIRLIGCYHVSQQNTFTGKLTEEMLDDVIGRLHSTWSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGH8</accession>
    <name>A0A1Q2CGH8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Anaerobic dimethyl sulfoxide reductase subunit C (DMSO reductase anchor subunit)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10840</name>
        <name evidence="3" type="ORF">SAMN05428934_102136</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY52110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10840"/>
    <dbReference type="EnsemblBacteria" id="AQP45229">
        <property type="protein sequence ID" value="AQP45229"/>
        <property type="gene ID" value="RPIT_10840"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY52110">
        <property type="protein sequence ID" value="SDY52110"/>
        <property type="gene ID" value="SAMN05428934_102136"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10840"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019645">
        <property type="term" value="P:anaerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007059">
        <property type="entry name" value="DmsC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38095">
        <property type="entry name" value="PTHR38095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04976">
        <property type="entry name" value="DmsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY52110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="304" mass="33019" checksum="6DE98D5054AF3F76" modified="2017-04-12" version="1">MLHELPLVIFTIFAQMSVGSFVALGVIQLLGARVPAGTMEKVTRPALYAIGPLLVLGLAASTMHLGSPLRAPNAILHWQESWLSREILLGIAFLVLGAAFAITEWFKLFHFRLRQALAAATAVVGLLLVYAISQVYSLRTVPAWATSFTAIRFFTTTLLLGGLAVAAALVLTAFFRVRKGDVDESAMRLLTNSVRGIAFASLLLMAVKAIVWPFYTSWLANHPEPAAQESLRVLYEQYGVWSGVQAAAVLLGLALLGFLLYRLSGGHAGRRLLPTIALVTFAIVFIGEFVGRMLFYVSMVRTGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGK2</accession>
    <name>A0A1Q2CGK2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10910</name>
        <name evidence="3" type="ORF">SAMN05428934_102122</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY51714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45241">
        <property type="protein sequence ID" value="AQP45241"/>
        <property type="gene ID" value="RPIT_10910"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY51714">
        <property type="protein sequence ID" value="SDY51714"/>
        <property type="gene ID" value="SAMN05428934_102122"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10910"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY51714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="470" mass="51311" checksum="5F15A85B0D1A1CB6" modified="2017-04-12" version="1">MDQEARQTAEQLRTVDELRRFAEAHTITLMCDLAEQYQVHYSDVVEVLAERRVVVGGIGSPAVSEFIGLELAGLLRCPPIVAASKLAEALNLRHRHPRLFAAMQQLKVEAARACKAADLCSDLPVDVAELVTDEWVGKQEALGWTAALNLLKRLIVEADPARAADKERRRRAERGVYVWGLHEGAMNLTGCLDVLDARYLDAAVDRVADILAAHQPGQSKSALRAKALGVLANPAYALALLQQAAQPGLTDPDPDQAPSAPGAQRHDPHCLGALCGTITTPLANLRPRLELAVHVHTDAVGRLTGSARIDKAGHITTALLAQLLPDVAVTVQPVIDLAEVPAEDRYVPSVRLRKALMLTLDHEVFPYSHKRAAGLDLDHTQPFTPGQRHQTRIGNLAPLTRRTHRAKTAQAWRVRQPSPGKLNWTSPLGFAYEVTTSGTRMLRPLYPPSRASYDTGSRQPTHGTPQARDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGN8</accession>
    <name>A0A1Q2CGN8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pyruvate carboxylase</fullName>
            <ecNumber evidence="7">6.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">RPIT_11140</name>
        <name evidence="16" type="ORF">SAMN05428934_10276</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1T</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1</strain>
        </source>
    </reference>
    <reference evidence="15" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + hydrogencarbonate + pyruvate = ADP + H(+) + oxaloacetate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20844"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <dbReference type="EC" id="6.4.1.1" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY50302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11140"/>
    <dbReference type="EnsemblBacteria" id="AQP45281">
        <property type="protein sequence ID" value="AQP45281"/>
        <property type="gene ID" value="RPIT_11140"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY50302">
        <property type="protein sequence ID" value="SDY50302"/>
        <property type="gene ID" value="SAMN05428934_10276"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11140"/>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004736">
        <property type="term" value="F:pyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006090">
        <property type="term" value="P:pyruvate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003379">
        <property type="entry name" value="Carboxylase_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005930">
        <property type="entry name" value="Pyruv_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02436">
        <property type="entry name" value="PYC_OADA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001594">
        <property type="entry name" value="Pyruv_carbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01235">
        <property type="entry name" value="pyruv_carbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7 9" id="KW-0067">ATP-binding</keyword>
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    <keyword evidence="15" id="KW-0670">Pyruvate</keyword>
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        <location>
            <begin position="1"/>
            <end position="454"/>
        </location>
    </feature>
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            <begin position="121"/>
            <end position="321"/>
        </location>
    </feature>
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            <begin position="529"/>
            <end position="797"/>
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    </feature>
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            <begin position="1056"/>
            <end position="1132"/>
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            <position position="117"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        <ligand>
            <name>ATP</name>
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            <position position="235"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <location>
            <position position="538"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
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        <location>
            <position position="610"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="10">
        <location>
            <position position="707"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
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        <location>
            <position position="736"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
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        <location>
            <position position="738"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
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            <position position="871"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
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    </evidence>
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            <dbReference type="PROSITE" id="PS50968"/>
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        <source>
            <dbReference type="PROSITE" id="PS50975"/>
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        <source>
            <dbReference type="PROSITE" id="PS50991"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP45281.1"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY50302.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
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    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="1134" mass="122809" checksum="8144FE9CFBCFEBC4" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGW3</accession>
    <name>A0A1Q2CGW3_9ACTN</name>
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        <recommendedName>
            <fullName evidence="7">L-fucose isomerase</fullName>
            <shortName evidence="7">FucIase</shortName>
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        <name evidence="12" type="ORF">SAMN05428934_1025</name>
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    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Converts the aldose L-fucose into the corresponding ketose L-fuculose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-fucose = L-fuculose</text>
            <dbReference type="Rhea" id="RHEA:17233"/>
            <dbReference type="ChEBI" id="CHEBI:2181"/>
            <dbReference type="ChEBI" id="CHEBI:17617"/>
            <dbReference type="EC" id="5.3.1.25"/>
        </reaction>
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        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate degradation; L-fucose degradation; L-lactaldehyde and glycerone phosphate from L-fucose: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
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        <property type="gene ID" value="SAMN05428934_1025"/>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Fuc/Ara_isomerase_C"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Fucose_isomerase_N/cen_sf"/>
    </dbReference>
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        <property type="entry name" value="Fucose_isomerase_N2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02952">
        <property type="entry name" value="Fucose_iso_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="fucI"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="4 7 11" id="KW-0413">Isomerase</keyword>
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    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fucose_iso_N1" evidence="9">
        <location>
            <begin position="4"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Fucose_iso_N2" evidence="10">
        <location>
            <begin position="173"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Fucose_iso_C" evidence="8">
        <location>
            <begin position="389"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="335"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="359"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
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        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
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        <location>
            <position position="526"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
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        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07881"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF07882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP45344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY48091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="589" mass="65499" checksum="B77C1E025F9C2957" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGZ7</accession>
    <name>A0A1Q2CGZ7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4185 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_11685</name>
        <name evidence="4" type="ORF">SAMN05428934_106138</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11685"/>
    <dbReference type="EnsemblBacteria" id="AQP45377">
        <property type="protein sequence ID" value="AQP45377"/>
        <property type="gene ID" value="RPIT_11685"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93705">
        <property type="protein sequence ID" value="SDY93705"/>
        <property type="gene ID" value="SAMN05428934_106138"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11685"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025442">
        <property type="entry name" value="DUF4185"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13810">
        <property type="entry name" value="DUF4185"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544493" description="DUF4185 domain-containing protein" evidence="1">
        <location>
            <begin position="34"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4185" evidence="2">
        <location>
            <begin position="173"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY93705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="392" mass="43049" checksum="16F7E40D688BC349" modified="2017-04-12" version="1">MKYRPLTTKAAAGLAALALTSTGVMVFGQTATAAPATTQRECSLVQEELVVTSAEPNDRTEQFANYGDTSGRWVGADSTYSVQLKDGSTAWLFSDTVLGTVVDGALDMDTLGFINNSIVLERGGELGPTVTGGTEADPQAIFGPPAADSWYWLGAGYAAPNGDLQIGINRYDKFGPGQWDWAWDHTAIGTVDPKTWEVTDVTTVDVDSNVQWTSWYERTQGKTYIYGVDDQGALKQAHVARVAGHDISRVDKWEYWTGSEWSRDAADSAPILDHVANEFSVTEFRDGYLLVTHDTSELFSSKVVAYTSCDPTGPFVNKTHLFSTPETGLWGSYGDPNVFTYNSHVHPQFSDDDTLLVSYNVNTFDNEHIFDDVTIYRPRFWTVTVADSETTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH07</accession>
    <name>A0A1Q2CH07_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycine betaine ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_11740</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11740"/>
    <dbReference type="EnsemblBacteria" id="AQP45387">
        <property type="protein sequence ID" value="AQP45387"/>
        <property type="gene ID" value="RPIT_11740"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11740"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031460">
        <property type="term" value="P:glycine betaine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005892">
        <property type="entry name" value="Gly-betaine_transp_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01186">
        <property type="entry name" value="proV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="20"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="75"/>
            <end position="82"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="429" mass="46913" checksum="9D12E1C477699EF8" modified="2017-04-12" version="1">MISAGHVNPFPAPRSDVSAIQASHVYKIFGRRPESGVTRLNEGATRDDLRKQGLTAAVIDASFEVEPGEIFVVMGLSGSGKSTLIRMVNGLLPMTAGEMIIHGNDLGKLSKPALRKVRRENISMVFQHFALLPHRTVGENVAYGLKIQGLNRIDREAKADEALKMADLDGWGGYKPGELSGGMQQRVGLARALASETDILLMDEAFSALDPLIRRGMQDQLIELQRKLDKTILFITHDLNEAMRLGDRIAMMRDGRIEQIGTAEDILNDPASNYVARFVADVDRTRVLTAGSIAEPPYAVLGSDQGPQAAHKLLREHQPSWLLVVGRDRTPKGFVWEEDVARAVRTGQRELPFSDVHEMHTVQEDTAINELFELSAQHRAPLVVLDGHERVVGVIPRVTLLAAAGQAATSDVEDDPVLNDQADLEGIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH50</accession>
    <name>A0A1Q2CH50_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycine betaine/proline transport system substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_11755</name>
        <name evidence="5" type="ORF">SAMN05428934_106124</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11755"/>
    <dbReference type="EnsemblBacteria" id="AQP45390">
        <property type="protein sequence ID" value="AQP45390"/>
        <property type="gene ID" value="RPIT_11755"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93429">
        <property type="protein sequence ID" value="SDY93429"/>
        <property type="gene ID" value="SAMN05428934_106124"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11755"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007210">
        <property type="entry name" value="ABC_Gly_betaine_transp_sub-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04069">
        <property type="entry name" value="OpuAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544483" evidence="2">
        <location>
            <begin position="26"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="OpuAC" evidence="3">
        <location>
            <begin position="33"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY93429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="291" mass="31777" checksum="44EB9503E0D85027" modified="2017-04-12" version="1">MTTNAVRRIGGALLAGTMALGLAACAETEAGDKEISIGYIPPWSDTRVAAALMTYKAEELGYEVEWEDVGEPPLLFAGVAEGDIDVYASAWAERNHAAFMNEFGDQLEDLGPYYEGAGNFLAVPEYSAITSIDEIPDHAEALDGRIIGIEAGAGLTKQVQEDVLPAYGLDQSMEFVTSSTTAMLAELKGAIDSQEEIVVTLWAPYWAATEFNVRPLEDPQGAFGETEGMHYVATVGFSEEHPEIAQWVSDFLVDEEEFASLENMILNEYEEGEELEAVEAWLEDHPDVFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH57</accession>
    <name>A0A1Q2CH57_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_12055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45444">
        <property type="protein sequence ID" value="AQP45444"/>
        <property type="gene ID" value="RPIT_12055"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12055"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="313" mass="33123" checksum="20F489CA56FA2E4A" modified="2017-04-12" version="1">MIGTGFDVTLNHVTDRARLLIASALGAPTSYEVGRTIYVEPDVDGVTLQVESTTGQDMSPSAKAFITLAPVGGRERILLTDLDVGGHRVVEVASLRAVGDGKSELSTIGGANVETPPLVRQAQLSAAGALGLRGNKLRSRQSIDIAIVIDGTASMRTWLREGALTAVAQCISGVDLVVGHDEKLDLRVAGSRDPWRSVAAMEVSQEIERQFASIGQISRVELYEPIPSGGQAWCVVTDHAPDVIPETVALIIVLCGPGADRVISAVSGDPRVFCLEVDPFRPASVPALDEASVHRLVSATLMAYRLETEGEQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHA4</accession>
    <name>A0A1Q2CHA4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="12">Peptide/nickel transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_12410</name>
        <name evidence="12" type="ORF">SAMN05428934_104203</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY80632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12410"/>
    <dbReference type="EnsemblBacteria" id="AQP45506">
        <property type="protein sequence ID" value="AQP45506"/>
        <property type="gene ID" value="RPIT_12410"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY80632">
        <property type="protein sequence ID" value="SDY80632"/>
        <property type="gene ID" value="SAMN05428934_104203"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="112"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="232"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="108"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="376"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="412"/>
            <end position="419"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP45506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY80632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="693" mass="74516" checksum="5F8FFB6746BC5EFE" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHN9</accession>
    <name>A0A1Q2CHN9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Transaldolase</fullName>
            <ecNumber evidence="6 7">2.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tal</name>
        <name evidence="8" type="ORF">RPIT_12800</name>
        <name evidence="9" type="ORF">SAMN05428934_104127</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate</text>
            <dbReference type="Rhea" id="RHEA:17053"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 7">Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 7">Belongs to the transaldolase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.2" evidence="6 7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY78482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12800"/>
    <dbReference type="EnsemblBacteria" id="AQP45575">
        <property type="protein sequence ID" value="AQP45575"/>
        <property type="gene ID" value="RPIT_12800"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY78482"/>
        <property type="gene ID" value="SAMN05428934_104127"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12800"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00955">
        <property type="entry name" value="Transaldolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00493">
        <property type="entry name" value="Transaldolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004732">
        <property type="entry name" value="Transaldolase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018225">
        <property type="entry name" value="Transaldolase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="PTHR10683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036915">
        <property type="entry name" value="Trnald_Bac_Plnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00876">
        <property type="entry name" value="tal_mycobact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01054">
        <property type="entry name" value="TRANSALDOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0704">Schiff base</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="7">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY78482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="358" mass="38496" checksum="6C129F2E9EEFF741" modified="2017-04-12" version="1">MNDRLKQLSQAGVSIWLDDLSRDRLTSGNLAELIAEKSVVGVTTNPSIFAAALSDGDAYAEQLAGMSDVADAITQATTTDVRDACDLFADIYAATDGYDGRVSIEVEPSLAHDTEQTVAQAAQLHDLVDRENVLIKIPATKAGLPAITQTIARGISVNVTLIFAVERYHEVMEAYLDGLEQADAAGLDLSTIHSVASIFISRIDAEVDKRLDDLGRADLKGKAAIANAQVALADFQEVFSSDRFKALKAKGANYQRPLWASTSTKDPALPDTLYVSELIADGVVNTMPEKTLEAFADHGEVGKSMERTAQEGVRTLAEIAEAGVDFDDVFRVLEEEGVQKFADSWTELQATVRTALDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHP8</accession>
    <name>A0A1Q2CHP8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13205"/>
    <dbReference type="EnsemblBacteria" id="AQP45648">
        <property type="protein sequence ID" value="AQP45648"/>
        <property type="gene ID" value="RPIT_13205"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13205"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003759">
        <property type="entry name" value="Cbl-bd_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036594">
        <property type="entry name" value="Meth_synthase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02607">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="32"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding" evidence="2">
        <location>
            <begin position="196"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="316" mass="33577" checksum="CAB908D7746D014E" modified="2017-04-12" version="1">MARAYPGYCHAARVCLRFVEDGQRGRREADDIYTVKQASQLTGIPEATLRMWERRYRIVFPHRSASGFRLYDDGQLDRLREMAAQVNGGVPASRAAQAILDAAASWPRPEAGGHTGDDLVAAAATLDPLTLDNVIGRAFARADFDEVATGWLQPQITALGDAWADGRLTVAQEHFASAGLMRAIGAVFDAAPPASGAAVLVGLPPRERHELALYAFAACLRRRGVNVIYLGADVPATDWVSAAVESHARAAVIGVSARRAGPKAQEVADQLGALTPPVSVWAGGSHRDLVEGVHQLPDPVSEAAAVLHLSLTTGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHT2</accession>
    <name>A0A1Q2CHT2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized conserved protein, DUF885 familyt</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_13310</name>
        <name evidence="2" type="ORF">SAMN05428934_10425</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY75675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13310"/>
    <dbReference type="EnsemblBacteria" id="AQP45667">
        <property type="protein sequence ID" value="AQP45667"/>
        <property type="gene ID" value="RPIT_13310"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY75675">
        <property type="protein sequence ID" value="SDY75675"/>
        <property type="gene ID" value="SAMN05428934_10425"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13310"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY75675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="551" mass="60795" checksum="17A4362188F6518C" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHT3</accession>
    <name>A0A1Q2CHT3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13125"/>
    <dbReference type="EnsemblBacteria" id="AQP45633">
        <property type="protein sequence ID" value="AQP45633"/>
        <property type="gene ID" value="RPIT_13125"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13125"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="251" mass="26536" checksum="D8603D76006E8945" modified="2017-04-12" version="1">MASHTGDRAKDVAGTAAAEAGAVKDTATAAGAQVAETAKQQAGNVAAEAKFQTRRLVDESVAELKTQAGTGQHHLAELIRSLSGELQSMANGTNESGPMVDLVSRAERFGNDAASWLDSKQPDDVMAEVRRYAARNPWKFLAISAGVGFVGARLARGLQGAKADENDSRSNRDLTYVAPEHRPYDPTGASYPAGGQPTSTGAYPTTPVVGDQYAENSPTAHPGVGAEYPGTERPFDETPRREDPWDQQGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHT6</accession>
    <name>A0A1Q2CHT6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Na+/H+-dicarboxylate symporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Sodium:proton antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_13330</name>
        <name evidence="8" type="ORF">SAMN05428934_10421</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY75555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13330"/>
    <dbReference type="EnsemblBacteria" id="AQP45671">
        <property type="protein sequence ID" value="AQP45671"/>
        <property type="gene ID" value="RPIT_13330"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY75555">
        <property type="protein sequence ID" value="SDY75555"/>
        <property type="gene ID" value="SAMN05428934_10421"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13330"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PTHR42865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY75555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="407" mass="42458" checksum="278AD846DD13EBEA" modified="2017-04-12" version="1">MSEQSTTKFQFGLLPRIIVAILLGIAFGLVLPDAVVRIFVTFNHVFGQLLNFVIPLIIVGLIAPAIADLGRGAGKWLAVTAGIAYGSTLTAGLIAFGASMLVLPRVLDGQAAESLTNPEDALLAPFFELQITPLFGVMSALVLAFIVGIGITAVPGDVMRRGFDEFREIIGLVISKMIIPLLPIYIFGIFLNMTRAGQVFTVITTFLGVIVFVFILTVVVLLLQFSVAGAVAGKNPLRMLVTMLPAYMTALGTSSSAATIPVTLRQAIKLGVTPAVASFTVPLCATIHLAGSTLKITSFSIAVMLLFGIPIDPATMIGFVLMLGIMMVAAPGVPGGAIMTAAGLLTSMLGFTDPQVGLMIATYIAIDSFGTATNVTGDGAIATVVDRLISRTSRRDAGRAQTAEVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHY6</accession>
    <name>A0A1Q2CHY6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cadmium resistance protein CadD, predicted permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Cadmium transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13360</name>
        <name evidence="3" type="ORF">SAMN05428934_10415</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY75363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_016997609.1">
        <property type="nucleotide sequence ID" value="NZ_FNPU01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13360"/>
    <dbReference type="EnsemblBacteria" id="AQP45675">
        <property type="protein sequence ID" value="AQP45675"/>
        <property type="gene ID" value="RPIT_13360"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY75363">
        <property type="protein sequence ID" value="SDY75363"/>
        <property type="gene ID" value="SAMN05428934_10415"/>
    </dbReference>
    <dbReference type="GeneID" id="44527687"/>
    <dbReference type="KEGG" id="tfl:RPIT_13360"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004676">
        <property type="entry name" value="Cd-R_transporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03596">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY75363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="200" mass="20765" checksum="D22F8B926A1FD952" modified="2017-04-12" version="1">MILTSVLQAMGLFAATNIDDIIVLSLFFARGAGQRGTTARILAGQYLGFAGILGAAVLVTIGAGAFLPSAAIPYFGLIPLGLGLWAAWQAWRGDDDDDDDEAKVAGKKVGVWTVAGVTLANGGDNIGVYTPVFLSVEPLAVVAYCIVFLALVAVLVALAKFVATRPPIAEVLERWEHILFPIVLIGLGIVILVSGGAFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI11</accession>
    <name>A0A1Q2CI11_9ACTN</name>
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        <submittedName>
            <fullName evidence="3">Polysaccharide pyruvyl transferase</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">SAMN05428934_11134</name>
    </gene>
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP45752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ12218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13830"/>
    <dbReference type="EnsemblBacteria" id="AQP45752">
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        <property type="gene ID" value="RPIT_13830"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ12218"/>
        <property type="gene ID" value="SAMN05428934_11134"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PS_pyruv_trans" evidence="1">
        <location>
            <begin position="14"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ12218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="370" mass="40553" checksum="BE6E3D991DE88746" modified="2017-04-12" version="1">MSAVGIVTLGGYTNFGNRLQNYALQEVLKSLGVERVEAIDGLPRAESRLVRAKRLALTPPQELFERVRQRGAGIRPDTYSSPPERQAAIRAFSEEFIQVAPAGFQDMSTEELALYSHFVVGSDQVWNPAYTHANPEWFLSFAPEGRRIAYAASFGVPSIPKYAAGRYRNGLRGLTTVSVREERASELVRELAGLDAQVVLDPTMVLEPSRWHELARRPHRLSGGGYVAKFMLAAGDGTPASGADLSGVEGFARRKDLEIVDLHDPIDPELLAMGPLEFIGAIQGSELVVTDSFHTAVFAVLFHRPFLLVGRGGMNSRFETLLSHTGLTDRFLAQADNLDGATEIDWSAVDDRLATARSKSLGFLRTSLQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI27</accession>
    <name>A0A1Q2CI27_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14020</name>
        <name evidence="3" type="ORF">SAMN05428934_11715</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000017">
        <property type="protein sequence ID" value="SDZ20953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14020"/>
    <dbReference type="EnsemblBacteria" id="AQP45779">
        <property type="protein sequence ID" value="AQP45779"/>
        <property type="gene ID" value="RPIT_14020"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ20953">
        <property type="protein sequence ID" value="SDZ20953"/>
        <property type="gene ID" value="SAMN05428934_11715"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14020"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ20953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="279" mass="31153" checksum="9240F088CC923F3D" modified="2017-04-12" version="1">MTAQVGIVIPCFNDLADHVREAVESALGQDVPVDVVVVDDGSTRAETLTMLEDLPPSVKVIHTRNSGPAAARNRGVEILATEFVLPLDADDRISPNFARAASSGLARDEDVFIAYADVIFFGDATGHDKKASEVRLADILTANRLPSCSMFRRSDWERIGGYDESLRVGHEDYEFWVRLLAEGGRAVKAANAVFYHRIRAGSRQSQQGLEEAAVRATRAAIARNNPDHREALLTETGVALHLLNRENRRLRAQLAWYHRRYGWTWRLARRLRDQGRGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI31</accession>
    <name>A0A1Q2CI31_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CoA-disulfide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13620"/>
    <dbReference type="EnsemblBacteria" id="AQP45720">
        <property type="protein sequence ID" value="AQP45720"/>
        <property type="gene ID" value="RPIT_13620"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13620"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="463"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="548" mass="58123" checksum="00824684341293BD" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI61</accession>
    <name>A0A1Q2CI61_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">CRP/FNR family transcriptional regulator, anaerobic regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_14135</name>
        <name evidence="5" type="ORF">SAMN05428934_1128</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ14319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14135"/>
    <dbReference type="EnsemblBacteria" id="AQP45802">
        <property type="protein sequence ID" value="AQP45802"/>
        <property type="gene ID" value="RPIT_14135"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ14319">
        <property type="protein sequence ID" value="SDZ14319"/>
        <property type="gene ID" value="SAMN05428934_1128"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14135"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00034">
        <property type="entry name" value="HTHCRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="12"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="3">
        <location>
            <begin position="146"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ14319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="225" mass="24760" checksum="985731183A2B5C5A" modified="2017-04-12" version="1">MSEDTCVAKVPIFRGLTPEEQREVADFARPVMASPNEQVMTAGSSRRRLLVVHSGRVRVVHLLPNGREHVVRVLGEGDVVGEDAFVLGRRPTHYAYADTDAQLCTFDHDDLARLVARYPGIALRMLQIQSERLANAERMLASMGGAEVGTRLAAYLLDLPSRQSDEGVLVELPMAKKDVASYLGTSPETLSRRLREFVDAGSIELRGRRGVLIRDVDALLTQAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIG1</accession>
    <name>A0A1Q2CIG1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Predicted N-acetyltransferase YhbS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14675</name>
        <name evidence="3" type="ORF">SAMN05428934_10983</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_000376623.1">
        <property type="nucleotide sequence ID" value="NZ_FNPU01000009.1"/>
    </dbReference>
    <dbReference type="SMR" id="A0A1Q2CIG1"/>
    <dbReference type="EnsemblBacteria" id="AQP45897">
        <property type="protein sequence ID" value="AQP45897"/>
        <property type="gene ID" value="RPIT_14675"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06176">
        <property type="protein sequence ID" value="SDZ06176"/>
        <property type="gene ID" value="SAMN05428934_10983"/>
    </dbReference>
    <dbReference type="GeneID" id="29371629"/>
    <dbReference type="KEGG" id="tfl:RPIT_14675"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ06176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="166" mass="18311" checksum="3EF06FD62AE25C9C" modified="2017-04-12" version="1">MDSEEPPNVRVACSGDIDEVVRLMHDAAAWMSAKGTPAWDVARIDRTFAETFVLRSELLVASCSDGIVGCCTLSAEDPEFWPDALKGEAAYLHKLAVRRTHAGRGVSSALIEACRHAARTQGCAKLRLDCHPNLRGLYERLGFTHVDTFNPGWDPTFIAERLELEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIH9</accession>
    <name>A0A1Q2CIH9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 11">Phosphate acetyltransferase</fullName>
            <ecNumber evidence="5 11">2.3.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Phosphotransacetylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">RPIT_14425</name>
        <name evidence="15" type="ORF">SAMN05428934_109131</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1T</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1</strain>
        </source>
    </reference>
    <reference evidence="14" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Involved in acetate metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>acetyl-CoA + phosphate = acetyl phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:19521"/>
            <dbReference type="ChEBI" id="CHEBI:22191"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">In the N-terminal section; belongs to the CobB/CobQ family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.8" evidence="5 11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ07105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14425"/>
    <dbReference type="EnsemblBacteria" id="AQP45855">
        <property type="protein sequence ID" value="AQP45855"/>
        <property type="gene ID" value="RPIT_14425"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ07105">
        <property type="protein sequence ID" value="SDZ07105"/>
        <property type="gene ID" value="SAMN05428934_109131"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14425"/>
    <dbReference type="UniPathway" id="UPA00340">
        <property type="reaction ID" value="UER00459"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008959">
        <property type="term" value="F:phosphate acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010766">
        <property type="entry name" value="DRTGG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016475">
        <property type="entry name" value="P-Actrans_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004614">
        <property type="entry name" value="P_AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042113">
        <property type="entry name" value="P_AcTrfase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042112">
        <property type="entry name" value="P_AcTrfase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002505">
        <property type="entry name" value="PTA_PTB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028979">
        <property type="entry name" value="Ser_kin/Pase_Hpr-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07085">
        <property type="entry name" value="DRTGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01515">
        <property type="entry name" value="PTA_PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006107">
        <property type="entry name" value="PhpActrans_proteobac"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="216"/>
            <end position="317"/>
        </location>
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        <location>
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            <end position="679"/>
        </location>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022679"/>
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            <dbReference type="ARBA" id="ARBA00031108"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF07085"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="AQP45855.1"/>
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    </evidence>
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            <dbReference type="EMBL" id="SDZ07105.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
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    </evidence>
    <sequence length="685" mass="73218" checksum="256871FF9998421C" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIJ8</accession>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Schumann P."/>
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            <dbReference type="PubMed" id="26869509"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">RP1</strain>
        </source>
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            </authorList>
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        </source>
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        </source>
    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="321" mass="32943" checksum="F7D93CEA3D8762D1" modified="2017-04-12" version="1">MSSDPVLAEVWRGEFLEGLHHGALAVTGPSGETRFSFGDVGSPMLPRSAVKPFQAIAMLRHGLDLEGAELALAAASHSGEPFHLEAVLRILDGAGLDVRALGNTAGLPIDGRAESDWLAAGRHEERLAHNCSGKHAAMLLTCVRAGWPTEGYLDPDHPLQRAAREAIAEFTGEAPAAPLVDGCGAPAFVASLAGLARAFGTLASASDGPARLVADAYRAHPEYASGSRRYEAVLHREVPGLVCKQGAEGVLAIGLADGTGIAIKVNDGHDRAAVAAAVAALGSLGRATQNVCALDPYPVLGHGRAVGRVVASAHLVGSLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    </dbReference>
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            <end position="255"/>
        </location>
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        </source>
    </evidence>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="277" mass="29422" checksum="F76A025E585F6AE7" modified="2017-04-12" version="1">MPTLSTPDGVTLHYTDSGGAGRPVVFVHGWPLSGAAFSRNVPAFVDAGYRIVTYDRRGFGASSAPTGDINYDILADDLGTVLEDLDLNDVVLVGFSMGGGEVARYLGRGEADRVSAAVFSGSITPALCITDDNPDGAMPFDGFQSMSDACREDRDGFLEQFVGWFYSTEAGGLQVDEETRAAALDIARQSDPDTAADAILLWATDLRDDCRSISVPTLVIHGDGDINVPAVKSSTRMPEYVEGAEVVLLEGGPHGVNDSQPEQWEGAILDFLSRHGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIZ3</accession>
    <name>A0A1Q2CIZ3_9ACTN</name>
    <protein>
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    </gene>
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
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    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP46089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY96246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="128" mass="14228" checksum="606C6314439A7D4B" modified="2017-04-12" version="1">MGKLRLTARGPADVGEVWARYTQPRRWAGWAPHLREVQYPEGVIEPDTTGVVRGVGLAARFRIDSLDEEARTWAWTVRLGPLQVTFDHGVEEEPDGSCAWVVIHAPWPVVVVYAPIARYALGRLVAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ15</accession>
    <name>A0A1Q2CJ15_9ACTN</name>
    <protein>
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    </protein>
    <gene>
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    <organism evidence="3 4">
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        <lineage>
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    <reference evidence="3 4" key="1">
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                <person name="Singh P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="AQP46107"/>
        <property type="gene ID" value="RPIT_09450"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09450"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01277">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039384">
        <property type="entry name" value="HINT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46648">
        <property type="entry name" value="PTHR46648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="7"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="1">
        <location>
            <begin position="100"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="145" mass="16199" checksum="42F49C5DFF6F54E6" modified="2017-04-12" version="1">MNKDGCPFCEIVLRDDPDAREVYRDEYVVAFFPTEPAVLGHTMVVPRKHVADIWKLDEETAGHLARATVRLAGAIREALHPEGLNVIQSNGEAATQTVFHLHVHLVPRWDGDAMGPIWPEGTDYSEAGKDDTLVRVREACRSMKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ46</accession>
    <name>A0A1Q2CJ46_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rhomboid family intramembrane serine protease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Rhomboid family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_10555</name>
        <name evidence="8" type="ORF">SAMN05428934_102194</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY53929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10555"/>
    <dbReference type="EnsemblBacteria" id="AQP46124">
        <property type="protein sequence ID" value="AQP46124"/>
        <property type="gene ID" value="RPIT_10555"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY53929">
        <property type="protein sequence ID" value="SDY53929"/>
        <property type="gene ID" value="SAMN05428934_102194"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10555"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="51"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP46124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY53929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="196" mass="20694" checksum="061DB630A8D8292B" modified="2017-04-12" version="1">MTEPTARRATLRSALLVVGSLLALMWALEILDTVTLNALDAYGIEPRQASDLPNILWSPLLHFGWAHLISNSVPFLVLGVLVYVSGFGRWLVATLSSVIASGLAAWALAPIGSITAGASGVIFGWLTFLLVRGFFTKKPGQIGLAVLVFLLYGGVLLGVLPGAPGVSWQAHLGGAVGGVLAAWWMSRRGHRYGVGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ69</accession>
    <name>A0A1Q2CJ69_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FeoA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13725</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP46176">
        <property type="protein sequence ID" value="AQP46176"/>
        <property type="gene ID" value="RPIT_13725"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13725"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007167">
        <property type="entry name" value="Fe-transptr_FeoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038157">
        <property type="entry name" value="FeoA_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04023">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00899">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeoA" evidence="2">
        <location>
            <begin position="7"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="79" mass="8672" checksum="0BA74F998B26A3CE" modified="2017-04-12" version="1">MVEQSTRTLDALPIGESASIVCFDADDAVCRRLFDLGFTPGEDVVRLRQAPLGDPLMFRVGGIELVLRRAEAKRILVQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBD8</accession>
    <name>A0A1Q2CBD8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00125</name>
        <name evidence="3" type="ORF">SAMN05428934_10920</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ04915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43424">
        <property type="protein sequence ID" value="AQP43424"/>
        <property type="gene ID" value="RPIT_00125"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ04915">
        <property type="protein sequence ID" value="SDZ04915"/>
        <property type="gene ID" value="SAMN05428934_10920"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00125"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ04915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="144" mass="15282" checksum="F7B1742E97E5B8B0" modified="2017-04-12" version="1">MEPHSPEHASAMLDQLRDDRVRLNAMTETPWWVPIALGLITGVWVASPAVGDRTVGYTMALVSVAVLVLLARRQMGVKLRISGASVWVLAVIWLAITLTAYSVALGLISLQLTAWVAVPALAAAAVTVGMARSIDRRARAAAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBE3</accession>
    <name>A0A1Q2CBE3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00180</name>
        <name evidence="4" type="ORF">SAMN05428934_1098</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
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    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ04667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43433">
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        <property type="protein sequence ID" value="SDZ04667"/>
        <property type="gene ID" value="SAMN05428934_1098"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00180"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
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            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
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        <location>
            <begin position="40"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
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            <dbReference type="EMBL" id="SDZ04667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="246" mass="25413" checksum="037E11F72BA157ED" modified="2017-04-12" version="1">MEERRLDERRSNANVWIIVGVIAVLGAIGLYVLLTQPGDGPTASPTPTVTVTSTAVSTETAPAEPTQATTEATVTETATESASAPATSEAPSPSPVEETSEAAAEPPDEDWGEFPPQNYATAPTLGTNIPDTVGEWTADPATSDHHSDGSAVAYGKGDQVLSVRYYNDSFWQWGATVANFENPAYVGDFVCGTLPAADGLRLSASCLAVTKTGMLQFTQPAAEGGEAPIEALAANATEILGLLAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBN2</accession>
    <name>A0A1Q2CBN2_9ACTN</name>
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            <fullName evidence="2">bPH_2 domain-containing protein</fullName>
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    </protein>
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        <name evidence="4" type="ORF">SAMN05428934_10586</name>
    </gene>
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        <name type="scientific">Tessaracoccus flavus</name>
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        <lineage>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
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    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY85722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00665"/>
    <dbReference type="EnsemblBacteria" id="AQP43512">
        <property type="protein sequence ID" value="AQP43512"/>
        <property type="gene ID" value="RPIT_00665"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY85722">
        <property type="protein sequence ID" value="SDY85722"/>
        <property type="gene ID" value="SAMN05428934_10586"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005182">
        <property type="entry name" value="DUF304"/>
    </dbReference>
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        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
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        <location>
            <begin position="74"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY85722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="162" mass="17800" checksum="4FE987AC13C652CA" modified="2017-04-12" version="1">MDDLFAPPGTPWQRLSPNYLKMKLILIPVVWLLLAAPALLVAFLWGPSWAGWAAVAVVAGWIAWRMLRAPLVFKRWGYAERDEDVYLTKGLVFRQLACVPYGRMQLVQVSSGPLQRAFGLASVEMITASSQGGIAIPGLPADDAAALRDRLIRRGETQQAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBR0</accession>
    <name>A0A1Q2CBR0_9ACTN</name>
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        <name evidence="2" type="ORF">RPIT_00835</name>
        <name evidence="3" type="ORF">SAMN05428934_105120</name>
    </gene>
    <organism evidence="2 4">
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
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    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43542">
        <property type="protein sequence ID" value="AQP43542"/>
        <property type="gene ID" value="RPIT_00835"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86605">
        <property type="protein sequence ID" value="SDY86605"/>
        <property type="gene ID" value="SAMN05428934_105120"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00835"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="126"/>
        </location>
    </feature>
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            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="AQP43542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY86605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="135" mass="13892" checksum="A1B4B6990AADE1A5" modified="2017-04-12" version="1">MTQQQTLGHIDVPASGPAFWRAAWSRRHTVTFAVAAVAMFLMLTSARPATSFLDGALLGLAAAVGALTLATYVPPAGVRLREHLVGGSCGAVPAIVTLGAPVLLSQSANAIPPLLLLLTCYAFAAAKRITDHASC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBS3</accession>
    <name>A0A1Q2CBS3_9ACTN</name>
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    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
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        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43550">
        <property type="protein sequence ID" value="AQP43550"/>
        <property type="gene ID" value="RPIT_00875"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00875"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012636931" evidence="1">
        <location>
            <begin position="32"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="64" mass="6582" checksum="20E1BCAFE8C153DC" modified="2017-04-12" version="1">MKRNAWWWRALAAVVAVIIGVVLAGCSASNEASDMPAGAPEPAVGRDAGECPSRVAMRRATATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBS6</accession>
    <name>A0A1Q2CBS6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Nucleobase:cation symporter-2, NCS2 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_00910</name>
        <name evidence="9" type="ORF">SAMN05428934_105134</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00910"/>
    <dbReference type="EnsemblBacteria" id="AQP43557">
        <property type="protein sequence ID" value="AQP43557"/>
        <property type="gene ID" value="RPIT_00910"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87000">
        <property type="protein sequence ID" value="SDY87000"/>
        <property type="gene ID" value="SAMN05428934_105134"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00910"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006042">
        <property type="entry name" value="Xan_ur_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00801">
        <property type="entry name" value="ncs2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01116">
        <property type="entry name" value="XANTH_URACIL_PERMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="428"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="457"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP43557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY87000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="496" mass="50933" checksum="C890FD634AB85BC6" modified="2017-04-12" version="1">MTATTAVHPVDEVPAAPKLLALGLQHVLVMYAGAIAVPLIVGRALQLSPNDVAFLISADLFACGIVTILQAFGATQWFGIRLPVMMGVTFAAVGPMVAIAMANPGSEGARQLFGSVMAAGVVAMLIAPLVSRLLRFFPPVVTGTIILVIGVSLMRIGINWIFGNPVGPTAPTVVDPSHSEWLTTVDDLASAPGGTVPPIPPGLSPAPSLPNPLYATLGDLAISAAVLVAIVLVARFGKGFVANISVLLGIVVGSIIAAFAGKVTFDSVVEADWFAFVTPFHFGLPLFDPVMVVTMSLVMVVVLIESTGMFLALGDLTGRKVTRPMLSAGLRTDGLGTLIGGIFNTFPYTSFSQNVGLVGVTGVRSRFVCVAGGGILIVLGLVPKMGALVEALPTSVLGGAGIAMFGMVAATGIRILSNVDFAGNRNSLLVVAISLGIGMIPLVAPDFSQWMPAEIHPLIESGILLATFSAVVLNAFLNGTTPDADAARKAAAMADH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBT6</accession>
    <name>A0A1Q2CBT6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aspartate/tyrosine/aromatic aminotransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">DinB superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00975</name>
        <name evidence="3" type="ORF">SAMN05428934_105146</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00975"/>
    <dbReference type="EnsemblBacteria" id="AQP43568">
        <property type="protein sequence ID" value="AQP43568"/>
        <property type="gene ID" value="RPIT_00975"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87319">
        <property type="protein sequence ID" value="SDY87319"/>
        <property type="gene ID" value="SAMN05428934_105146"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00975"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="16"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY87319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="174" mass="18654" checksum="2BC7ED87DC544B97" modified="2017-04-12" version="1">MDALDILRDTASRPLESLRAIADRITPANLNLHPAGHDNSIAWLLWHTGREIDVQLAHLTGGDELWHAQGFRDRSGLGRAGDAIGYGHSPDEARAIAVDDASVLVDYVAGCVDALLAYLDTLSEADLDDVVDDNWDPPVTRGVRLVSIIDDAAQHIAQAAYVTGMPTDTSPPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBV7</accession>
    <name>A0A1Q2CBV7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phage integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_01125</name>
        <name evidence="5" type="ORF">SAMN05428934_105176</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY88130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01125"/>
    <dbReference type="EnsemblBacteria" id="AQP43594">
        <property type="protein sequence ID" value="AQP43594"/>
        <property type="gene ID" value="RPIT_01125"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY88130">
        <property type="protein sequence ID" value="SDY88130"/>
        <property type="gene ID" value="SAMN05428934_105176"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01125"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="212"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY88130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="453" mass="50699" checksum="0445690E6F3BFD56" modified="2017-04-12" version="1">MAEGRRAWGKVRQLPSGRYQASYVLRSVRGGDQGTRYTALQTFDAKGDAWGWLDREHRLIDRGDWTPPIERFREAEEERQRKEVARQAAAAVPTIAAYGSRYLERADLAATSRDRYRQLFRFYILAEPATITRRGMVKDKPVAKHGIGGVRVTELTRADVRLWWQGLPVSTRESSCRQAYDLLRAIMNAAVEAELIEVNPVQVKAATQAQASRERNLDPLPIDVLYAVAEQMPDPWRLGVLLGGVLGLRSGEVRALQRRDFSLNVEVPTVKVHQSVKEAEGKVEIGPLKTARKGIAFRTLPIPAALVGDVRTHLREHTQLGRTGLLFWRTRDGGPVKSADWLRAFKKACKTVADHLEEDAARRLEQSGEQESEESQRIRELLTGQGGYVFHGTRVTGLTWAYRLSGGNLRAVQAIAGHTSPKMALRYQRAEMDYLAAVAGNVSSMIEASTRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC09</accession>
    <name>A0A1Q2CC09_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_01480</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01480"/>
    <dbReference type="EnsemblBacteria" id="AQP43648">
        <property type="protein sequence ID" value="AQP43648"/>
        <property type="gene ID" value="RPIT_01480"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01480"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="DoxX"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="392"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="464"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="498"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="169"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="254"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="534" mass="55850" checksum="36F1E9121F8479F7" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC19</accession>
    <name>A0A1Q2CC19_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_01590</name>
        <name evidence="3" type="ORF">SAMN05428934_10866</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43663">
        <property type="protein sequence ID" value="AQP43663"/>
        <property type="gene ID" value="RPIT_01590"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02182">
        <property type="protein sequence ID" value="SDZ02182"/>
        <property type="gene ID" value="SAMN05428934_10866"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01590"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021517">
        <property type="entry name" value="DUF3180"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11377">
        <property type="entry name" value="DUF3180"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ02182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="162" mass="16717" checksum="4E18ACA62EA61D58" modified="2017-04-12" version="1">MSEQPKLGLTTGRQALVAVLAGALVCALILAAFELAGDFPPVVPWSVPILFVVLSAAVAIYARLLPKRLEERRVSSQEAVAALGIGKSSIMTGALFAGAHVVYVMRYLQLFDAPLPSARVIQGAATIATALLLAVAGAFLERACVVSDDDDDDDAGGAAEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC31</accession>
    <name>A0A1Q2CC31_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Hypoxanthine phosphoribosyltransferase</fullName>
            <ecNumber evidence="1 2">2.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_01560</name>
        <name evidence="5" type="ORF">SAMN05428934_10860</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>diphosphate + IMP = 5-phospho-alpha-D-ribose 1-diphosphate + hypoxanthine</text>
            <dbReference type="Rhea" id="RHEA:17973"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="2.4.2.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from hypoxanthine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.8" evidence="1 2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ02073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01560"/>
    <dbReference type="EnsemblBacteria" id="AQP43661">
        <property type="protein sequence ID" value="AQP43661"/>
        <property type="gene ID" value="RPIT_01560"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ02073">
        <property type="protein sequence ID" value="SDZ02073"/>
        <property type="gene ID" value="SAMN05428934_10860"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01560"/>
    <dbReference type="UniPathway" id="UPA00591">
        <property type="reaction ID" value="UER00648"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052657">
        <property type="term" value="F:guanine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004422">
        <property type="term" value="F:hypoxanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005904">
        <property type="entry name" value="Hxn_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01203">
        <property type="entry name" value="HGPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="3">
        <location>
            <begin position="18"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ02073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="183" mass="20049" checksum="9A508F0EF72989F0" modified="2017-04-12" version="1">MDAADVSQDLAKVLFTSDEIQARVAEVAAQIDEDYAGRDVLMVGVLNGAVMVMSDLQRAMRSHVEMDWMAVSSYGSGTQSSGVVRILKDLNTDLEGRDVIVVEDIIDTGLTLSYLMSNLASRGPASLEIMTMFRKPDAAQMEVPVKYVGFEIPNEFVVGYGLDYAGRYRNLRDVGTLAPHVYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC62</accession>
    <name>A0A1Q2CC62_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thymidylate kinase</fullName>
            <ecNumber evidence="3">2.7.4.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">dTMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tmk</name>
        <name evidence="5" type="ORF">RPIT_01465</name>
        <name evidence="6" type="ORF">SAMN05428934_10841</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>ATP + dTMP = ADP + dTDP</text>
            <dbReference type="Rhea" id="RHEA:13517"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58369"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the thymidylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000008">
        <property type="protein sequence ID" value="SDZ01721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01465"/>
    <dbReference type="EnsemblBacteria" id="AQP43645">
        <property type="protein sequence ID" value="AQP43645"/>
        <property type="gene ID" value="RPIT_01465"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ01721">
        <property type="protein sequence ID" value="SDZ01721"/>
        <property type="gene ID" value="SAMN05428934_10841"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01465"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:thymidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="4">
        <location>
            <begin position="8"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDZ01721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="205" mass="22361" checksum="084DA0CCC871F06E" modified="2017-04-12" version="1">MTGIFIAFEGGDSVGKSTQVERLAGWLSSRGIAHVVTRQPGGTPVGAELRRLVLDHSSGDVSARAEALMYAADKAQHVYELIGPALERGEVVISDRYVDSMIAYQGAGRALDIDEVSTIAWWAVGQLRPHLTILLDADPTDAVETIAEKDRLEDAGIDLHRRARHFFLDLAAADPHRYLVLDARLTREELAATIATRVAEQLAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCC2</accession>
    <name>A0A1Q2CCC2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted alpha-1,6-mannanase, GH76 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_02040</name>
        <name evidence="2" type="ORF">SAMN05428934_1015</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY22449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02040"/>
    <dbReference type="EnsemblBacteria" id="AQP43740">
        <property type="protein sequence ID" value="AQP43740"/>
        <property type="gene ID" value="RPIT_02040"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY22449">
        <property type="protein sequence ID" value="SDY22449"/>
        <property type="gene ID" value="SAMN05428934_1015"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02040"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY22449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="357" mass="38846" checksum="50D8E629A7807175" modified="2017-04-12" version="1">MSLPAADAAVRRADEAARSVVEVFGQRVFGWVPGTHLGAVARPGSDGGEWHYWWQAHFLDCLLDAAERDSPSVSTGLIGRQHRGIWLRNGMRFRNSYFDDMAWLALACQRAGLSTGRLHADLRSAVTDEWGGGAFWHRARDFKNTAATGPIALYLARSGDHGTARTLVGWLQTHLRDPGTGLVRDGLRLEGGPSPVLVPHVFTYNQGPILGAMLALGDRASLTAAAELVDDVARHLVRPGTSVLITHGSGDGGLFTGILTRYLALAACDARLPSSAREQASVLVRDTAEELWRGRETRGWRGRPVTVFPSDTGDPRVPHRVELSTQLQAWMALEAAVRLRCLADGLDVEPALDQMRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCC7</accession>
    <name>A0A1Q2CCC7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell wall-associated hydrolase, NlpC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_02100</name>
        <name evidence="5" type="ORF">SAMN05428934_10117</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY22800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02100"/>
    <dbReference type="EnsemblBacteria" id="AQP43751">
        <property type="protein sequence ID" value="AQP43751"/>
        <property type="gene ID" value="RPIT_02100"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY22800">
        <property type="protein sequence ID" value="SDY22800"/>
        <property type="gene ID" value="SAMN05428934_10117"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02100"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544405" evidence="2">
        <location>
            <begin position="29"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="NlpC/P60" evidence="3">
        <location>
            <begin position="190"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP43751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY22800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="306" mass="32890" checksum="E72CD116FA66AFEC" modified="2017-04-12" version="1">MLKKTLHLALATVTGAVLALAPSGPAQAADTDVYTVPGHHLVNGRYWQTECEKYSSTVVRCSTEIWAKKVVQHNGRYVSHEGWVFNNLTYLPSNRGDWTGNPLATPGTWKGDDGRSWRTECDTDATGRNGCRTYVVTTALSQTYDGIVSSKTWAVNNIVQFATSTKPAVTTIPAAAPALSGVPVEQPIRSSIGQQVVDYALSKVGSRYVYATAGPSTFDCSGLTSWAYRQVGIDLPRSSRTQYSAGTRISKSQLQPGDLVFYYSPISHVGIYVGNGKIVDAANPRTGVRTASLDSMPYAGAVRVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCG9</accession>
    <name>A0A1Q2CCG9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Isocitrate dehydrogenase [NADP]</fullName>
            <ecNumber evidence="1">1.1.1.42</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Oxalosuccinate decarboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_02410</name>
        <name evidence="7" type="ORF">SAMN05428934_10181</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19629"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="4">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="4">Binds 1 Mg(2+) or Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the monomeric-type IDH family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.42" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY24718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02410"/>
    <dbReference type="EnsemblBacteria" id="AQP43812">
        <property type="protein sequence ID" value="AQP43812"/>
        <property type="gene ID" value="RPIT_02410"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY24718">
        <property type="protein sequence ID" value="SDY24718"/>
        <property type="gene ID" value="SAMN05428934_10181"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02410"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004450">
        <property type="term" value="F:isocitrate dehydrogenase (NADP+) activity"/>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Isocitrate_DH_NADP_mono"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="IDH"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="monomer_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 5" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="130"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="80"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
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        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
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        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
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    <feature type="binding site" evidence="3">
        <location>
            <position position="543"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
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        <location>
            <begin position="580"/>
            <end position="581"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
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        <location>
            <position position="585"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
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        <location>
            <begin position="596"/>
            <end position="598"/>
        </location>
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            <name>NADP(+)</name>
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        </ligand>
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        <location>
            <position position="645"/>
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        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
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            <position position="253"/>
        </location>
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        <location>
            <position position="416"/>
        </location>
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        <source>
            <dbReference type="EMBL" id="AQP43812.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY24718.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="737" mass="79266" checksum="2CE2C5B605DEB4B2" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCQ4</accession>
    <name>A0A1Q2CCQ4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_02500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
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        <property type="entry name" value="Integrase_recombinase_N"/>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
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        <location>
            <begin position="81"/>
            <end position="286"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="295" mass="31261" checksum="28856170058E2D99" modified="2017-04-12" version="1">MSPLQLIGDRRARELTPSDIEAALRKLATVGGIKGKPLSHRSRTYALGALRQAFKFAQREGWLQGNPAALAKVQGKPAKTRQSQRWTVAQLQGFRAYVDSAYATPARLAAEPWVPAAMRLALCGLRRSEVLGLGWGSVDIEQGTVDIHVSRTASGPGRSTAIGAPKTANSVRRVAVETLHPGTHAVLRALWLAQGQPAEGLVIRDSLGDPVHPDTLSWRFKTLCSEAGVPFPGAIHATRHTLATALEEAGVPSNQGAALLGHDVQTYQRFYLVTDQDAAGAAATVAGSIFATASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCQ7</accession>
    <name>A0A1Q2CCQ7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Formate acetyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.54</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Pyruvate formate-lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_02965</name>
        <name evidence="12" type="ORF">SAMN05428934_101194</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>acetyl-CoA + formate = CoA + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:11844"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Fermentation; pyruvate fermentation; formate from pyruvate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.54" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY28049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02965"/>
    <dbReference type="EnsemblBacteria" id="AQP43902">
        <property type="protein sequence ID" value="AQP43902"/>
        <property type="gene ID" value="RPIT_02965"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY28049">
        <property type="protein sequence ID" value="SDY28049"/>
        <property type="gene ID" value="SAMN05428934_101194"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02965"/>
    <dbReference type="UniPathway" id="UPA00920">
        <property type="reaction ID" value="UER00891"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008861">
        <property type="term" value="F:formate C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01678">
        <property type="entry name" value="PFL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005949">
        <property type="entry name" value="Form_AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019777">
        <property type="entry name" value="Form_AcTrfase_GR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001150">
        <property type="entry name" value="Gly_radical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004184">
        <property type="entry name" value="PFL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01228">
        <property type="entry name" value="Gly_radical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02901">
        <property type="entry name" value="PFL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01255">
        <property type="entry name" value="pyr_form_ly_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00850">
        <property type="entry name" value="GLY_RADICAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51149">
        <property type="entry name" value="GLY_RADICAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51554">
        <property type="entry name" value="PFL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="5 7 8" id="KW-0556">Organic radical</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFL" evidence="10">
        <location>
            <begin position="9"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine radical" evidence="9">
        <location>
            <begin position="629"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="modified residue" description="Glycine radical" evidence="7">
        <location>
            <position position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP43902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY28049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="752" mass="84107" checksum="112B6A9D128337AF" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCR0</accession>
    <name>A0A1Q2CCR0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Broad specificity phosphatase PhoE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_02880</name>
        <name evidence="2" type="ORF">SAMN05428934_101176</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY27464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02880"/>
    <dbReference type="EnsemblBacteria" id="AQP43887">
        <property type="protein sequence ID" value="AQP43887"/>
        <property type="gene ID" value="RPIT_02880"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY27464">
        <property type="protein sequence ID" value="SDY27464"/>
        <property type="gene ID" value="SAMN05428934_101176"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02880"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY27464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="251" mass="27997" checksum="BCD3F905BC215DC9" modified="2017-04-12" version="1">MSTVATEGSTRGPAEIVLVRHGESLGNVADRAAIAAKAHRLDLPANDEMIDLSEEGQRQADALGRHLGRLPAEERPTVVISSPYQRARSTAERALAGLDLEVLLDERLRERELGIFDGVTWYGIKADHPEESDRRDRVGKFYYRPPGGESWADVVLRIRSLLVELQARYPGERVWLFSHEAVILAFRYVLEGLEVSRVLALQKEEPIANCSMTRYADRDGALELQARDDVSAIEDESAVTREPSHAEEGDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCT5</accession>
    <name>A0A1Q2CCT5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD-dependent epimerase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Uronate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_03130</name>
        <name evidence="4" type="ORF">SAMN05428934_101227</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03130"/>
    <dbReference type="EnsemblBacteria" id="AQP43932">
        <property type="protein sequence ID" value="AQP43932"/>
        <property type="gene ID" value="RPIT_03130"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29082">
        <property type="protein sequence ID" value="SDY29082"/>
        <property type="gene ID" value="SAMN05428934_101227"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03130"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="2">
        <location>
            <begin position="6"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY29082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="255" mass="28640" checksum="C1C8086FE0D22A25" modified="2017-04-12" version="1">MTKRRILITGANGGVGTLLSERLRDEYELIRHAHRPDENDPDLLAADLVDYPAVLALMDGVDTVVHMAGAASPESSWDAVLNANIIGVRNALEAAREAGVRRFVFASSNHVMGMYDRDEEWPVYPHMLPRPDSLYGVSKAFGETIGRYYHDEFGLEFIALRIGWISDDPDAGADVDLLRAMWLSYDDTVDVVRSAIEADVTFGLYYAVSDNPHRRWSTTNTRLELGYRPAHDVTRHSSRPENPDEPTPDDWPRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCX0</accession>
    <name>A0A1Q2CCX0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">DNA-directed RNA polymerase subunit alpha</fullName>
            <shortName evidence="11">RNAP subunit alpha</shortName>
            <ecNumber evidence="2 11">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">RNA polymerase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">Transcriptase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rpoA</name>
        <name evidence="13" type="ORF">RPIT_03370</name>
        <name evidence="14" type="ORF">SAMN05428934_101274</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 11">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="domain">
        <text evidence="11">The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the RNA polymerase alpha chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2 11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY30552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03370"/>
    <dbReference type="EnsemblBacteria" id="AQP43973">
        <property type="protein sequence ID" value="AQP43973"/>
        <property type="gene ID" value="RPIT_03370"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30552">
        <property type="protein sequence ID" value="SDY30552"/>
        <property type="gene ID" value="SAMN05428934_101274"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03370"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00059">
        <property type="entry name" value="RNApol_bact_RpoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011773">
        <property type="entry name" value="DNA-dir_RpoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011260">
        <property type="entry name" value="RNAP_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32108">
        <property type="entry name" value="PTHR32108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03118">
        <property type="entry name" value="RNA_pol_A_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="SSF55257"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="SSF56553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02027">
        <property type="entry name" value="rpoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RPOLD" evidence="12">
        <location>
            <begin position="18"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha N-terminal domain (alpha-NTD)" evidence="11">
        <location>
            <begin position="1"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha C-terminal domain (alpha-CTD)" evidence="11">
        <location>
            <begin position="247"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP43973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY30552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="340" mass="37337" checksum="189EF9A1C28B60F5" modified="2017-04-12" version="1">MLIAQRPTLSEEVVSDHRSRFIIEPLEPGFGYTLGNSLRRTLLSSIPGASVTSIKIEGNQHEFSTLEGVVEDVTEIIMNIKGLVLSSEEDEPVVMYLRKAGAGTVTAGDIQPPAGVEIHNPEMHIATLNDSGKLEMELVVERGRGYVSSVLNKDPDAEIGRIPVDSIYSPVLKVTYKVEATRVAQRTDFDRLIIDVETKPSMAPRDAVASAGHTLVELFGLARELNVDAEGIEIGPSPVDEQIAESLNLPVEDLELSVRSYNCLKREGIHTVGELVARSEEDLLDIRNFGSKSIDEVKETLVGLGLSLRDSHPGFDPLQAIERYDEDNDDDVDFAETEQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCX3</accession>
    <name>A0A1Q2CCX3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diaminopimelate decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03120</name>
        <name evidence="3" type="ORF">SAMN05428934_101225</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03120"/>
    <dbReference type="EnsemblBacteria" id="AQP43930">
        <property type="protein sequence ID" value="AQP43930"/>
        <property type="gene ID" value="RPIT_03120"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29019">
        <property type="protein sequence ID" value="SDY29019"/>
        <property type="gene ID" value="SAMN05428934_101225"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03120"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038732">
        <property type="entry name" value="HpyO_NAD-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13454">
        <property type="entry name" value="NAD_binding_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_binding_9" evidence="1">
        <location>
            <begin position="4"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY29019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="498" mass="52476" checksum="BC1DF9965E112A32" modified="2017-04-12" version="1">MRVAIVGAGPRGLFAVERLWAHAAPGTCLDVVLFDPRDPGVGAAYDPTQPEYLRLNVNSAVVSAAWPGEDTIPSFNAWRLSTGEREPLEPFPPRALVGRYLGWFWGWLNQQTPSGSLLAHRSLNVAELAASGAGWVVDGEIFDEVLLATGHEGSWPGQLHGDGVIPAVFPVQRWLGEDDVPPGCRVAFRGAALTFIDAALALTEGRGGRFIGDWATGLAYERSGREPRTLWPVGRSGRWMDPKPQPGTLLAEADPEILRVGRAAVLSAETPTASLGAVHTTAVALGADPDRLASLLDPGRGDATEALRQRLTAVAGSSDPGTSWALGHAWRGLYDALRYRFEGTVEGFAPFARLASTLERVAFGPPPVNAAKILALIEAGLIDPTSLERAHFDGASPIGLPAAPDVIVDAVLPPPGVVPGSLVGRLVDDGVIVSPAGRRGVAVAPDANCLDRDGVPVPGLACIGRATEDVVIGNDTLNRALHPAVDLWARRITQKGSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD15</accession>
    <name>A0A1Q2CD15_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_03590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03590"/>
    <dbReference type="EnsemblBacteria" id="AQP44008">
        <property type="protein sequence ID" value="AQP44008"/>
        <property type="gene ID" value="RPIT_03590"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03590"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="114" mass="12876" checksum="3E041C78362B83B9" modified="2017-04-12" version="1">MHNVDVGWFSRRKREVSLAREAKQVPDALRDHLSEFVATRRGVEAWVEQPTSFNKPSILLVAADGESTRRGLPSADYGYDFAAAHGVPCYDAGVVPYPRRMREYGLRAKKQGQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD38</accession>
    <name>A0A1Q2CD38_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_03605</name>
        <name evidence="2" type="ORF">SAMN05428934_101322</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY32007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03605"/>
    <dbReference type="EnsemblBacteria" id="AQP44011">
        <property type="protein sequence ID" value="AQP44011"/>
        <property type="gene ID" value="RPIT_03605"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY32007">
        <property type="protein sequence ID" value="SDY32007"/>
        <property type="gene ID" value="SAMN05428934_101322"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03605"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY32007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="68" mass="7616" checksum="513C93BEBE34A6B8" modified="2017-04-12" version="1">MSYRWEPVSGAYSADELEAAGLKKSFEDQTAAEEWLALFFGELLTHGVAEVSLYEEDRLVYGPMSLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD76</accession>
    <name>A0A1Q2CD76_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03575</name>
        <name evidence="3" type="ORF">SAMN05428934_101316</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY31805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03575"/>
    <dbReference type="EnsemblBacteria" id="AQP44005">
        <property type="protein sequence ID" value="AQP44005"/>
        <property type="gene ID" value="RPIT_03575"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY31805">
        <property type="protein sequence ID" value="SDY31805"/>
        <property type="gene ID" value="SAMN05428934_101316"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03575"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007563">
        <property type="entry name" value="DUF554"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36111">
        <property type="entry name" value="PTHR36111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04474">
        <property type="entry name" value="DUF554"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY31805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="244" mass="24563" checksum="05A50A9F4885EC60" modified="2017-04-12" version="1">MFIGIGTVVNVATVVVGALLGLALGNRIPDRTKETITSVLGLFTVVIGGMSVVSMTSADLTGAVGSFAMIIVLASLLVGALVGSWLQVEYRLEQGATWLRGRFTASGDAARFVDGLVTSTLVFCVGPLAILGSLSDGLGRGAEQLLVKSVLDGFAAMAFASTLGWGVLASAGTVALIQGSLTALGYFAGDVLTVAQVDALTATGGVILLGLALRLLDLKQVPVGDLLPALLLAPPLVSVAAAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD81</accession>
    <name>A0A1Q2CD81_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">APH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_03900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03900"/>
    <dbReference type="EnsemblBacteria" id="AQP44064">
        <property type="protein sequence ID" value="AQP44064"/>
        <property type="gene ID" value="RPIT_03900"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03900"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="APH" evidence="2">
        <location>
            <begin position="127"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="315" mass="33449" checksum="7A50BD5A8C2B48F1" modified="2017-04-12" version="1">MDKDRKLPALGAGLPLVVHRLHKRAVALTPDRAIKILRPGRAPRVAAASTAVAVACAAAGFGAAEVLSSTDDVVEFSLLPGTTLYDLGRAGAQGESSDGLGSPFPSTSSLVPRERSGRRVVAGSSLAGDAQGAMEGWRALADGWPDFARTTLELPAHTSGDEIEVLRTWYGHALRFGSLDRLDELGAAVDEACEALAETPDPAVTLHRDLHDKQALWDGTQIHLLDLDTAARGEAALDLANLLVHVELRAMQGVLDRADDIAAILMGAVDKLEISAQRLAAYAQASRLRLAFLYSFRPASAPWLGAWTDQALTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDA5</accession>
    <name>A0A1Q2CDA5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">UDP-N-acetylmuramate--L-alanine ligase</fullName>
            <ecNumber evidence="4 11">6.3.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">UDP-N-acetylmuramoyl-L-alanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">murC</name>
        <name evidence="15" type="ORF">RPIT_04035</name>
        <name evidence="16" type="ORF">SAMN05428934_101410</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1T</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1</strain>
        </source>
    </reference>
    <reference evidence="15" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-alanine + UDP-N-acetyl-alpha-D-muramate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine</text>
            <dbReference type="Rhea" id="RHEA:23372"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the MurCDEF family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.8" evidence="4 11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY34366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04035"/>
    <dbReference type="EnsemblBacteria" id="AQP44084">
        <property type="protein sequence ID" value="AQP44084"/>
        <property type="gene ID" value="RPIT_04035"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY34366">
        <property type="protein sequence ID" value="SDY34366"/>
        <property type="gene ID" value="SAMN05428934_101410"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04035"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008763">
        <property type="term" value="F:UDP-N-acetylmuramate-L-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00046">
        <property type="entry name" value="MurC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005758">
        <property type="entry name" value="UDP-N-AcMur_Ala_ligase_MurC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01082">
        <property type="entry name" value="murC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 11" id="KW-0133">Cell shape</keyword>
    <keyword evidence="10 11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 11" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="12">
        <location>
            <begin position="17"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="14">
        <location>
            <begin position="119"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="13">
        <location>
            <begin position="321"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="121"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="AQP44084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="SDY34366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="482" mass="50556" checksum="77DB65FD797C3CB2" modified="2017-04-12" version="1">MLLNPIDVIPADQVGPVHFIAAGGSGMSGVARLYAQLGVKTSGSDQSDSTALQGLARAGVTTYVGHAPEQLGDAQTVVISSAIRSDNVELVEAKRRGLRIWHRSAALAALMLGKRGVSVAGTHGKTTTTAMTAVMLAEAGAQPSYVIGGPLSTTGVSSELGTGPAFVVEADESDASFLQYPTEIAVITNVEADHLVNWGTPQAYADGFRAFATRPTVQHVIINVDDPGSRQLAEDLVGEARHIVRYGEAPDADVRITDVRPEGNGVSATISYGDDSGRIVLQVPGNHNLANASAAYAAGRLLGLTHEAAVDALGRFEGTLRRFQLITDTAGIRVFDDYAHHPTEIRAALTAARRATEAGNEATGLSGRLIACFQPHLYSRTVDFADEFGEVMTLADIAVINDVCGAREDPIPGVTGELVVDAAKKHGAEEVVYVQEKYDLPAALNDIAQPGDLIITLGCGDVTIVGPLLADILKERPDAEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDB5</accession>
    <name>A0A1Q2CDB5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">4HBT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04095"/>
    <dbReference type="EnsemblBacteria" id="AQP44094">
        <property type="protein sequence ID" value="AQP44094"/>
        <property type="gene ID" value="RPIT_04095"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04095"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003736">
        <property type="entry name" value="PAAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00369">
        <property type="entry name" value="unchar_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="1">
        <location>
            <begin position="61"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="156" mass="16156" checksum="D3E115F38DF1373B" modified="2017-04-12" version="1">MGGQVSRLWVCLWQSAAMNSIPDWALAVASPLDTKMGLDLTELSAERVVGSIPVEGNQQPFGLLHGGASGVLVETLGSMGALAYGYPDRAGVGVDLNVTHVRGVRSGRVTGTATAVHLGRTIVVYAVEIVDDEGRTTATGRLTCHMTALPGTTPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDC9</accession>
    <name>A0A1Q2CDC9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Amino acid ABC transporter membrane protein 1, PAAT family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Amino acid ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_04235</name>
        <name evidence="9" type="ORF">SAMN05428934_101451</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY35663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04235"/>
    <dbReference type="EnsemblBacteria" id="AQP44119">
        <property type="protein sequence ID" value="AQP44119"/>
        <property type="gene ID" value="RPIT_04235"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY35663">
        <property type="protein sequence ID" value="SDY35663"/>
        <property type="gene ID" value="SAMN05428934_101451"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04235"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="15"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY35663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="215" mass="22927" checksum="3801DD0A27F3BAF1" modified="2017-04-12" version="1">MQVIIDNWPALMRAFGVTLQLLGMGALGSIVLGNLVALLRISPVASLRWIATLYTEIVRNTPLTLVFFFFAIVLPTLQIRFDYLLGAGIALSIYTSPFIAEALRSGINGVPIGQAEAARSLGLSFGQTVTSIVFPQAIRMVVAPLINVIIALTKNTSVAAGFYVVELVAESKVLANAHGDQVINILVAVACLYLVITIPLGQLAGVVERKVAVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDF3</accession>
    <name>A0A1Q2CDF3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Phosphoglucomutase, alpha-D-glucose phosphate-specific</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">Phosphonomutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_04400</name>
        <name evidence="12" type="ORF">SAMN05428934_101486</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY36554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04400"/>
    <dbReference type="EnsemblBacteria" id="AQP44148">
        <property type="protein sequence ID" value="AQP44148"/>
        <property type="gene ID" value="RPIT_04400"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY36554">
        <property type="protein sequence ID" value="SDY36554"/>
        <property type="gene ID" value="SAMN05428934_101486"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04400"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016868">
        <property type="term" value="F:intramolecular transferase activity, phosphotransferases"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="8">
        <location>
            <begin position="4"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="9">
        <location>
            <begin position="168"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="10">
        <location>
            <begin position="273"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="7">
        <location>
            <begin position="425"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY36554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="475" mass="52881" checksum="AF2394EF51E767F4" modified="2017-04-12" version="1">MARIKFGTGGWRAIIGDEFTRANVRLLCGALAQRIKEEGHAERGIVIGYDRRFLSDVSAHWAAEVFAGEGIACQIIKIAQAPTPLIMWTVKDRKLPYGMAITASHNPALYNGIKVFTAGGKDADEDVTHDVERRMETLEGDGEERIGLIDYDKAVKSGKVREINPFNGYIDSIINQVDMEAIRKADLKIALDPMFGVSRTSLQTILMTARCEVEVIHDRHDTLFGGRIPSPTSATLDTLKRYVVDNDCALGIATDGDADRLGVIDDKGNFLHPNQLLVILYYYLLKYKGWRGPVVRNVATTSLLDHVAEMFGEKCYEVPVGFKWISGKMLETDAIIGGESSGGLTVRGHISGKDGIYAAALLVEMIAVVGKSLSQIYDEITGQFPPHYMAEMDFKFDSERKPEILDTLMVRKEIPEFSATVVDTSYRDGAKIYFDNGWIIARFSGTEPLLRIFCEMPTREEAERACIEFREFLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDH7</accession>
    <name>A0A1Q2CDH7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">23S rRNA m(1)G-748 methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_04415</name>
        <name evidence="5" type="ORF">SAMN05428934_101489</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY36634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04415"/>
    <dbReference type="EnsemblBacteria" id="AQP44151">
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        <property type="gene ID" value="RPIT_04415"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY36634">
        <property type="protein sequence ID" value="SDY36634"/>
        <property type="gene ID" value="SAMN05428934_101489"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04415"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="3">
        <location>
            <begin position="89"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="2">
        <location>
            <begin position="94"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
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        <location>
            <position position="27"/>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:29105"/>
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            <position position="31"/>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
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        <location>
            <position position="70"/>
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        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
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        <location>
            <position position="182"/>
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        <ligand>
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        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44151.1"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY36634.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDI7</accession>
    <name>A0A1Q2CDI7_9ACTN</name>
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        </alternativeName>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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                <person name="Peterson S.W."/>
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        </citation>
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        <text evidence="3">Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.</text>
    </comment>
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        <subcellularLocation>
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        </subcellularLocation>
    </comment>
    <comment type="similarity">
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    </comment>
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    </dbReference>
    <dbReference type="GO" id="GO:0005737">
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        <property type="project" value="UniProtKB-SubCell"/>
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    </dbReference>
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            <begin position="21"/>
            <end position="182"/>
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    </feature>
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            <dbReference type="ARBA" id="ARBA00005912"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
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    </evidence>
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            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44166.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY37099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="185" mass="20835" checksum="5AC6EA98A894C697" modified="2017-04-12" version="1">MIAEIQKEASNKMSYAVDHAREDLATIRTGRAHPAMFNKIQADYYGAPTPLQQLATFTSTDPRSMMITPFDRSAIGAIEKAIREADLGVNPSNDGNAVRIVMPQLTEERRKEYIKMAKAKAEDARIAVRNVRRHSHDQLKKLQKDGEISEDDLSRAEKALDASTKKFVESIDEILKHKEAELNEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDJ7</accession>
    <name>A0A1Q2CDJ7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Melibiose permease/lactose/raffinose/galactose permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Sugar transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_04410</name>
        <name evidence="4" type="ORF">SAMN05428934_101488</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
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    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY36605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04410"/>
    <dbReference type="EnsemblBacteria" id="AQP44150">
        <property type="protein sequence ID" value="AQP44150"/>
        <property type="gene ID" value="RPIT_04410"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY36605">
        <property type="protein sequence ID" value="SDY36605"/>
        <property type="gene ID" value="SAMN05428934_101488"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04410"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039672">
        <property type="entry name" value="MFS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001927">
        <property type="entry name" value="Na/Gal_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11328">
        <property type="entry name" value="PTHR11328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00792">
        <property type="entry name" value="gph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="325"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="374"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="411"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY36605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="463" mass="50585" checksum="FB1A4B9CE435ED61" modified="2017-04-12" version="1">MESQPGRVTPGTRWGFGLGTLGRDMVAALVSMYLLFYLTDVLDISGTRLAVITAILVAMRIFDAVNDPFMGVLVDNTHTRWGKFKPWIFWGAILWGVATLLLFFDFGADGWGYVIAFTIVYLVYEIGYTINDISYWSMLPSLTRDQPERERIGVVARICANVGLFAVVVGIVPITSALGAALGSAEAAWFALAAALVAIMVVFQTLTLVFAREQVTARQEATPLREFLGVIVRNDQLLWVTVSMVAFMAGYITTTSFGLYYFKYIFGDEGAYAVFAAILGVTQITALALFPLASARFSREHIHLAATASCVTGYLVFLVSGDSLIVVGLAGVLLFAGQGAIQLLLVMFIADSVEYGEWKLGRRNESVTFSLQPFIYKLGNAIASAVVGATVIWSGIDRAESAADVTDEGAALVRLAMLVVPALLILVSYLVIRWRYRLNATFYAQIVDDLRERTRHGTQAPHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDL1</accession>
    <name>A0A1Q2CDL1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">RPIT_04765</name>
        <name evidence="3" type="ORF">SAMN05428934_101562</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY38417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04765"/>
    <dbReference type="EnsemblBacteria" id="AQP44212">
        <property type="protein sequence ID" value="AQP44212"/>
        <property type="gene ID" value="RPIT_04765"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY38417">
        <property type="protein sequence ID" value="SDY38417"/>
        <property type="gene ID" value="SAMN05428934_101562"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04765"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021660">
        <property type="entry name" value="DUF3253"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11625">
        <property type="entry name" value="DUF3253"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY38417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="162" mass="17688" checksum="E799C73524123601" modified="2017-04-12" version="1">MGAEIETTEDGHHIVVGGRRWRATDPAIPETLKAQLVGALMDARRAVKADGDAARHRVQDAKVALGERGDPWWEEATTEGLTTRIDSTIRALLRRRPDGTICPSEVSRVVGGDGWRDLMDAVRDRAWALRDRGEVDVLQAGAPVEPGARGPIRIGRGPQFPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDL6</accession>
    <name>A0A1Q2CDL6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmA</name>
        <name evidence="7" type="ORF">RPIT_04670</name>
        <name evidence="8" type="ORF">SAMN05428934_101541</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04670"/>
    <dbReference type="EnsemblBacteria" id="AQP44196">
        <property type="protein sequence ID" value="AQP44196"/>
        <property type="gene ID" value="RPIT_04670"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37875">
        <property type="protein sequence ID" value="SDY37875"/>
        <property type="gene ID" value="SAMN05428934_101541"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04670"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00539">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_L27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018261">
        <property type="entry name" value="Ribosomal_L27_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="PTHR15893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00062">
        <property type="entry name" value="L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00831">
        <property type="entry name" value="RIBOSOMAL_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY37875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="83" mass="8823" checksum="3CC0965591C8810F" modified="2017-04-12" version="1">MAHKKGASSTRNGRDSNAQRLGVKRYGGQVVGAGEILVRQRGTHFHPGDGVGRGGDDTLFALVQGEVQFGVKRGRRVINVLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDN6</accession>
    <name>A0A1Q2CDN6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_04790</name>
        <name evidence="2" type="ORF">SAMN05428934_101567</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY38552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04790"/>
    <dbReference type="EnsemblBacteria" id="AQP44216">
        <property type="protein sequence ID" value="AQP44216"/>
        <property type="gene ID" value="RPIT_04790"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY38552">
        <property type="protein sequence ID" value="SDY38552"/>
        <property type="gene ID" value="SAMN05428934_101567"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04790"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY38552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="295" mass="33108" checksum="C8C54E0DA16B4A99" modified="2017-04-12" version="1">MTTLEAQVWRAAAETHRVEVEGELADVVYRRDRGQRHPVDDFLFHYYNLRPSQLAQWHPGAGVALDDAAEYADRPFYSSVDGVARLDVGAFLAKRGATVVTARDLLAATASAAPRFGCFGMHEWAMVYRLEPDETRHPYLQLRFPPDALAKIVEDVGCRCSHFDAFRFFTPAAKPLNLVAPSRDRQAELDQPGCLHVNMDLYKWASKLSPAVPSTVLLDTFRLARRIRRVDMAASAYDLSDWGIEPIRVETPAGRADYVERQKGFAAEAAPLRTALLEIAEDLLNREPSLVRRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDV7</accession>
    <name>A0A1Q2CDV7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05360</name>
        <name evidence="3" type="ORF">SAMN05428934_10319</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY65523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44309">
        <property type="protein sequence ID" value="AQP44309"/>
        <property type="gene ID" value="RPIT_05360"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY65523">
        <property type="protein sequence ID" value="SDY65523"/>
        <property type="gene ID" value="SAMN05428934_10319"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05360"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY65523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="208" mass="20896" checksum="E6B82ABD200C21E5" modified="2017-04-12" version="1">MTTHTTTAGRQPSETPTAVRGISALRHPVVSGGLIGVIGGTAFLFAGLLGVSSPTQGPLRGLAAALATFTLAVILFRRRVLPELRPPAPGAARVYGVAVVVMLLLMPVTRLVAQALHAPTAQSALVAAVVGAHFLPFARVFHAPVFWWIGGSMVALGLGGALLAVLGMHVAGPAGAAAAGAAMLVIVAVQAFRQHAPGTTAATEQSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDX7</accession>
    <name>A0A1Q2CDX7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_05025</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05025"/>
    <dbReference type="EnsemblBacteria" id="AQP44255">
        <property type="protein sequence ID" value="AQP44255"/>
        <property type="gene ID" value="RPIT_05025"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05025"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="84"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="308" mass="34130" checksum="973DA3B88CBF93D3" modified="2017-04-12" version="1">MEIAKKRRGASRVREGVRALPWLVPTLILIFGVVLFPAGLMVYTSFFRFNARGIQRGDEPIGFDNYTGTAGALTFPGVPIQQIIINTLLWVVVVVVVTVLLSLALAQFLNKEFRGRKLIRLFIILPWACSVVMTATVFRYGLDERVGLFNRLLVDTGILDTMQAWTKDPIPAFWVSVFVAIYVSLPFTTYTVLAGLQSVPVDVLEAAHVDGAHSAQRYWFIVLPLLRPAIAVAALINIINVFNSLPILRVLQATPGYHDGHITTTLMYEYQVRLGPGVSSALSVLNFLFCLVIIAIYLAVVRPTKEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE04</accession>
    <name>A0A1Q2CE04_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aconitate hydratase A</fullName>
            <ecNumber evidence="6">4.2.1.3</ecNumber>
            <ecNumber evidence="7">4.2.1.99</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">(2R,3S)-2-methylisocitrate dehydratase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Iron-responsive protein-like</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Probable 2-methyl-cis-aconitate hydratase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">RNA-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="primary">acnA</name>
        <name evidence="21" type="ORF">RPIT_05610</name>
        <name evidence="22" type="ORF">SAMN05428934_10369</name>
    </gene>
    <organism evidence="21 23">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="21 23" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 23">RP1T</strain>
        </source>
    </reference>
    <reference evidence="22 24" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 24">RP1</strain>
        </source>
    </reference>
    <reference evidence="21" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = 2-methyl-cis-aconitate + H2O</text>
            <dbReference type="Rhea" id="RHEA:17941"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="ChEBI" id="CHEBI:57872"/>
            <dbReference type="EC" id="4.2.1.99"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Organic acid metabolism; propanoate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.3" evidence="6"/>
    <dbReference type="EC" id="4.2.1.99" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY66929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05610"/>
    <dbReference type="EnsemblBacteria" id="AQP44354">
        <property type="protein sequence ID" value="AQP44354"/>
        <property type="gene ID" value="RPIT_05610"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY66929">
        <property type="protein sequence ID" value="SDY66929"/>
        <property type="gene ID" value="SAMN05428934_10369"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05610"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00718"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00946"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047456">
        <property type="term" value="F:2-methylisocitrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047780">
        <property type="term" value="F:citrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01580">
        <property type="entry name" value="AcnA_IRP_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044137">
        <property type="entry name" value="AcnA_IRP_Swivel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006249">
        <property type="entry name" value="Aconitase/IRP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11670">
        <property type="entry name" value="PTHR11670"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="19">
        <location>
            <begin position="64"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase_C" evidence="20">
        <location>
            <begin position="731"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="414"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00019378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00031613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00031977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00033025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="AQP44354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="SDY66929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="937" mass="101461" checksum="B58B9CB9456A9F92" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE67</accession>
    <name>A0A1Q2CE67_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06015</name>
        <name evidence="3" type="ORF">SAMN05428934_103149</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44422">
        <property type="protein sequence ID" value="AQP44422"/>
        <property type="gene ID" value="RPIT_06015"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68944">
        <property type="protein sequence ID" value="SDY68944"/>
        <property type="gene ID" value="SAMN05428934_103149"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06015"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY68944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="77" mass="8349" checksum="0805C5F9BA073C2E" modified="2017-04-12" version="1">MTDDGYDANSPHDAVPGPNEETYIDEPVEDSGQAPDSSEEFAHGSDGAVPEDKIEAHRQHEANSPRQRVSNEATDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE85</accession>
    <name>A0A1Q2CE85_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="3 13">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">RPIT_05955</name>
        <name evidence="17" type="ORF">SAMN05428934_103137</name>
    </gene>
    <organism evidence="16 18">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 18" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">RP1T</strain>
        </source>
    </reference>
    <reference evidence="17 19" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">RP1</strain>
        </source>
    </reference>
    <reference evidence="16" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NAD(+) = (R)-N(6)-lipoyl-L-lysyl-[protein] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11 13">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="13">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="3 13"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05955"/>
    <dbReference type="EnsemblBacteria" id="AQP44413">
        <property type="protein sequence ID" value="AQP44413"/>
        <property type="gene ID" value="RPIT_05955"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68652">
        <property type="protein sequence ID" value="SDY68652"/>
        <property type="gene ID" value="SAMN05428934_103137"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05955"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11 13" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 13" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="15">
        <location>
            <begin position="5"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="14">
        <location>
            <begin position="347"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="445"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="179"/>
            <end position="186"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="318"/>
            <end position="321"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="42"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="AQP44413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="SDY68652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="466" mass="50103" checksum="6EC3552036B4AA18" modified="2017-04-12" version="1">MSSEYDVVVLGAGPGGYVAAIRASQLGLKVAVIEKRYWGGVCLNIGCIPTKSLLRNAELAHIFNHEADTFGIEGEVSFNYAKAYKRSRQVSDRMTKGIHYLMKKNKITEIDGWGTFLDAHTIEVELNGGEKEKVTFKNAIIAVGATTRMLPGTERSANVVTYEEQILADEVPGSVIVGGSGAIGTEFAFVMSQFGTDVTIVEYLDRMVPTEDAEISAELAKAYKKLGIKVLTSTKVESIEDTGSGVKVTVSPADGGEQKVLEADRFLSAIGFAPRIDGFGLENTGVEVTERKAIAIDDFMRTNVEHIFAIGDCTGKLMLAHTAEAQGVVAAETIGGAETQPINYDMIPRATYCQPQVASFGYTEQQAKDKGYDVKVSKFPFAANGKAWGLGDGSGFVKIVADARYNEILGAHMIGPDVTELLPELTLAQAYDLTAEEIGRNIHAHPTLSEALKEAAEGIAGHMINY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEA4</accession>
    <name>A0A1Q2CEA4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44433">
        <property type="protein sequence ID" value="AQP44433"/>
        <property type="gene ID" value="RPIT_06075"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06075"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="66" mass="7029" checksum="098D9AAEB7E43D27" modified="2017-04-12" version="1">MSVKARGREIILALASISLGLLALALSTTFTCSEVSCGPTLDPFALFFAVVAFIVAGLLLFGRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CED2</accession>
    <name>A0A1Q2CED2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 9">Chorismate synthase</fullName>
            <shortName evidence="8">CS</shortName>
            <ecNumber evidence="4 8 9">4.2.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">5-enolpyruvylshikimate-3-phosphate phospholyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">aroC</name>
        <name evidence="10" type="ORF">RPIT_06215</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21020"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="EC" id="4.2.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 9">
            <name>FMNH2</name>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
        </cofactor>
        <text evidence="8 9">Reduced FMN (FMNH(2)).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8 9">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 9">Belongs to the chorismate synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.5" evidence="4 8 9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06215"/>
    <dbReference type="EnsemblBacteria" id="AQP44457">
        <property type="protein sequence ID" value="AQP44457"/>
        <property type="gene ID" value="RPIT_06215"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06215"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004107">
        <property type="term" value="F:chorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07304">
        <property type="entry name" value="Chorismate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00300">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000453">
        <property type="entry name" value="Chorismate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035904">
        <property type="entry name" value="Chorismate_synth_AroC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020541">
        <property type="entry name" value="Chorismate_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085">
        <property type="entry name" value="PTHR21085"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01264">
        <property type="entry name" value="Chorismate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001456">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103263">
        <property type="entry name" value="SSF103263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00033">
        <property type="entry name" value="aroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00787">
        <property type="entry name" value="CHORISMATE_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00788">
        <property type="entry name" value="CHORISMATE_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00789">
        <property type="entry name" value="CHORISMATE_SYNTHASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8 9" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="7 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="135"/>
            <end position="137"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="256"/>
            <end position="257"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="315"/>
            <end position="319"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="398" mass="41761" checksum="2AB9B5AAE8557F8D" modified="2017-04-12" version="1">MLRYLTAGESHGQALIATMEGIPAHVRVGVPEISTNLARRRLGVGRGARMKFEADEVTLLGGFRHGETLGSPIAIMIGNTEWPKWEQVMAPGEVDAEEVGKLARNAPLTRPRPGHADLAGMQKYDFDEARPILERASARETAARVALGTVAQAFLRQAFGITVLSHVVELGQIRADRAELPTIEDLDAIDADPARCFDPGASAAMQAEVDACRRDGDTLGGVVEVVAWGLPPGLGSHSQGDRRLDGRLAGALMGIQAIKGVEIGDGFDLARSRGSAAHDEIVPGDAGIARASHRSGGTEGGMSTGEVLRVRAAMKPIATVPRALRTVDTATGDAATAHHQRSDVCAVPAAGVVAEAMVALVLAEAALEKFGGDSVAESRRNHAAYLADVEARGLRIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEF2</accession>
    <name>A0A1Q2CEF2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyltransferase (GNAT) family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06340</name>
        <name evidence="3" type="ORF">SAMN05428934_103213</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44477">
        <property type="protein sequence ID" value="AQP44477"/>
        <property type="gene ID" value="RPIT_06340"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70607">
        <property type="protein sequence ID" value="SDY70607"/>
        <property type="gene ID" value="SAMN05428934_103213"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06340"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="174"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY70607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="316" mass="34429" checksum="3756C9A88E8D4454" modified="2017-04-12" version="1">MASPHIDAYVEPHLSWRTLGPDDADELDHFRTQLEALDNSVLAGIAEGMTGGAPAIVPGQAVGGWDHYDSLSAYGLNYISANPDPRAYLMGGVHPTHRHLGIGTSLFRWQIAQAISWRDEHHPGRPLWLGSYAELGRPGLDRVARHYDFTPERYYYDLHRDLTVPIPLWVPEGVRLAPFVPQASEAVRRLHNICSQPLGGAEVTEDVWADRLCAADFRPDWSFLATVEGRVVGYAMSGIEEGGGGWTERFGVDPAHRGRGISLALLASCLRAMRDSGCTEAGIGIDTPDGVGVQRLAAELGYTTRDAVALLSKVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEG0</accession>
    <name>A0A1Q2CEG0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_06240</name>
        <name evidence="2" type="ORF">SAMN05428934_103193</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06240"/>
    <dbReference type="EnsemblBacteria" id="AQP44460">
        <property type="protein sequence ID" value="AQP44460"/>
        <property type="gene ID" value="RPIT_06240"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70067">
        <property type="protein sequence ID" value="SDY70067"/>
        <property type="gene ID" value="SAMN05428934_103193"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06240"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046165">
        <property type="entry name" value="DUF6167"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19664">
        <property type="entry name" value="DUF6167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY70067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="78" mass="8642" checksum="C4209EA8B2F38AA1" modified="2017-04-12" version="1">MRRLFWMMVGAGLAVYLVLRGRDLLHRLTPRGVQEQVAAKGHQAAAGFGDFAATFRAAMAEREAELRRELNIPATTTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEG7</accession>
    <name>A0A1Q2CEG7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methylmalonyl-CoA epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_06605</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methylmalonyl-CoA epimerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06605"/>
    <dbReference type="EnsemblBacteria" id="AQP44522">
        <property type="protein sequence ID" value="AQP44522"/>
        <property type="gene ID" value="RPIT_06605"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06605"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07249">
        <property type="entry name" value="MMCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017515">
        <property type="entry name" value="MeMalonyl-CoA_epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03081">
        <property type="entry name" value="metmalonyl_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="2">
        <location>
            <begin position="11"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="151" mass="16703" checksum="6FD346A044AFD187" modified="2017-04-12" version="1">MPMENSDLFICIDHVGLAVPDLDEAVKFHTETFGWRELHREVNEEQGVAEAMMGTGSQGEENAKIQLLAPLNENSTIAKFIDRNGPGMQQLAYRVADLDHVSSVLKERGMRLLFPEAKRGTGGSRINFVHPKDARGVLLELVELPKDAAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEP2</accession>
    <name>A0A1Q2CEP2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_06980</name>
        <name evidence="2" type="ORF">SAMN05428934_11049</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06980"/>
    <dbReference type="EnsemblBacteria" id="AQP44589">
        <property type="protein sequence ID" value="AQP44589"/>
        <property type="gene ID" value="RPIT_06980"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09045">
        <property type="protein sequence ID" value="SDZ09045"/>
        <property type="gene ID" value="SAMN05428934_11049"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06980"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024747">
        <property type="entry name" value="Pyridox_Oxase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12900">
        <property type="entry name" value="Pyridox_ox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ09045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="133" mass="13716" checksum="5E75B35AD93BE274" modified="2017-04-12" version="1">MSDPDQVSYFSRLDVEECWALLSEAEVGRIAWRGPAGIVIVPVNFQLVGRTIVFHTVEGSGLAALADGAEVSFQVDEIDGESAIGWSVLVQGRSGPAGGEASSVSWLGDGVTVGVSVSPAAIDGRVVSGNKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CER9</accession>
    <name>A0A1Q2CER9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MT0933-like antitoxin protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07060</name>
        <name evidence="3" type="ORF">SAMN05428934_11032</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44603">
        <property type="protein sequence ID" value="AQP44603"/>
        <property type="gene ID" value="RPIT_07060"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08655">
        <property type="protein sequence ID" value="SDZ08655"/>
        <property type="gene ID" value="SAMN05428934_11032"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07060"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028037">
        <property type="entry name" value="Antitoxin_Rv0909/MT0933"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14013">
        <property type="entry name" value="MT0933_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ08655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="70" mass="7459" checksum="AF3B0410CE73A2E2" modified="2017-04-12" version="1">MGLFDKARDLAAQHEDKIEDGIERGGDFVDDKTGGKYAGQVDQAQDFANNHLDEISGSDNVPPTTPVPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEU9</accession>
    <name>A0A1Q2CEU9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF305 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Uncharacterized conserved protein, DUF305 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_07275</name>
        <name evidence="5" type="ORF">SAMN05428934_11412</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000014">
        <property type="protein sequence ID" value="SDZ17985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07275"/>
    <dbReference type="EnsemblBacteria" id="AQP44633">
        <property type="protein sequence ID" value="AQP44633"/>
        <property type="gene ID" value="RPIT_07275"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ17985">
        <property type="protein sequence ID" value="SDZ17985"/>
        <property type="gene ID" value="SAMN05428934_11412"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07275"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005183">
        <property type="entry name" value="DUF305"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03713">
        <property type="entry name" value="DUF305"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544456" evidence="2">
        <location>
            <begin position="25"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="DUF305" evidence="3">
        <location>
            <begin position="67"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ17985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="217" mass="22647" checksum="AE266066EC5633B9" modified="2017-04-12" version="1">MSRTKQITATLAGLVLTATLAACADQSTTPPAATTTPTSSTSATATESASASASASTDVAADHSDQDTTFAQMMIIHHEGAIEMSELAIERAESPEVVALAERISAAQGPEIDEMTAWLSAWGEDVSPDDHGGMDMGGMDMNGMSQEEMMTQLDGLTGAEFDQAFLEAMIAHHEGAIGMSEQQLAEGQNPDAVALAEKIIADQQAEITEMQEILTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEV3</accession>
    <name>A0A1Q2CEV3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_07295</name>
        <name evidence="4" type="ORF">SAMN05428934_11416</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000014">
        <property type="protein sequence ID" value="SDZ18066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07295"/>
    <dbReference type="EnsemblBacteria" id="AQP44636">
        <property type="protein sequence ID" value="AQP44636"/>
        <property type="gene ID" value="RPIT_07295"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ18066">
        <property type="protein sequence ID" value="SDZ18066"/>
        <property type="gene ID" value="SAMN05428934_11416"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07295"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ18066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="179" mass="19157" checksum="F3985B8EC705B44B" modified="2017-04-12" version="1">MLAVEASAVSQTATVTYDPNQTSVAQLVGWVNDCGYHCTGLDLVTAAAWHLLMGAAGLMVFAAAVEGLPVIAWTPRFVLSLAFLALVGTAATTVAWFAEARRSQARHVDGVDVPDSGPWYRVGLRRIGRVAGRMDRRRAPRRVGGHVDHPSTTAPGPHTPDGCRPRRLVSHTAGHMNNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEV5</accession>
    <name>A0A1Q2CEV5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP-dependent DNA helicase DinG</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">ATP-dependent helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_07040</name>
        <name evidence="6" type="ORF">SAMN05428934_11036</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07040"/>
    <dbReference type="EnsemblBacteria" id="AQP44600">
        <property type="protein sequence ID" value="AQP44600"/>
        <property type="gene ID" value="RPIT_07040"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08742">
        <property type="protein sequence ID" value="SDZ08742"/>
        <property type="gene ID" value="SAMN05428934_11036"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07040"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="PTHR11472"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="23"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDZ08742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="675" mass="71201" checksum="B453CC2EF7C8206A" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEY6</accession>
    <name>A0A1Q2CEY6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">D-alanine--D-alanine ligase</fullName>
            <ecNumber evidence="7">6.3.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">D-Ala-D-Ala ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">D-alanylalanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ddl</name>
        <name evidence="11" type="ORF">RPIT_07130</name>
        <name evidence="12" type="ORF">SAMN05428934_11018</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + 2 D-alanine = ADP + D-alanyl-D-alanine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11224"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the D-alanine--D-alanine ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.4" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ08349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07130"/>
    <dbReference type="EnsemblBacteria" id="AQP44615">
        <property type="protein sequence ID" value="AQP44615"/>
        <property type="gene ID" value="RPIT_07130"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08349">
        <property type="protein sequence ID" value="SDZ08349"/>
        <property type="gene ID" value="SAMN05428934_11018"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07130"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008716">
        <property type="term" value="F:D-alanine-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00047">
        <property type="entry name" value="Dala_Dala_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000291">
        <property type="entry name" value="D-Ala_lig_Van_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005905">
        <property type="entry name" value="D_ala_D_ala"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011095">
        <property type="entry name" value="Dala_Dala_lig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011127">
        <property type="entry name" value="Dala_Dala_lig_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07478">
        <property type="entry name" value="Dala_Dala_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01820">
        <property type="entry name" value="Dala_Dala_lig_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039102">
        <property type="entry name" value="Ddl/VanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01205">
        <property type="entry name" value="D_ala_D_alaTIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00843">
        <property type="entry name" value="DALA_DALA_LIGASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00844">
        <property type="entry name" value="DALA_DALA_LIGASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 7 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="10">
        <location>
            <begin position="149"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR039102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDZ08349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="370" mass="39681" checksum="BFB754B7C0500744" modified="2017-04-12" version="1">MSDRTRVALIFGGQSSEHGISCLTAASVLKAIDRDRFDVVGVGISKTGRWTQVPLDVVAAYAIVDGVPPEVDEPVHDAVWMVGEHGCEVASRSGETLVDINAVDVAFALLHGPYGEDGTIQGMFEMMGIRYVGSGVTASAVGMDKHFMKVAFEAAGLPVGPYVAASAHRLTHDREAVLAEVEALEYPLFVKPARGGSSIGIVRVTEPGQLDAAIEEAQRFDPKIVIEQGFTGARELEVAVLGNPDAPDGCDASVLGEIRVNAKDGFYDYEAKYFDEDGAALDAPADVTPELAARIQELAKQAFHAVDAEGLVRADFFVADDDVWINEVNTMPGFTRISMYPTLWQASGLTYTDLVARLIELALQRPVGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF03</accession>
    <name>A0A1Q2CF03_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_07595</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07595"/>
    <dbReference type="EnsemblBacteria" id="AQP44686">
        <property type="protein sequence ID" value="AQP44686"/>
        <property type="gene ID" value="RPIT_07595"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07595"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="120"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="424"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="873"/>
            <end position="900"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="944" mass="105210" checksum="007C47C46A6FE3F8" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF77</accession>
    <name>A0A1Q2CF77_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ketol-acid reductoisomerase (NADP(+))</fullName>
            <shortName evidence="8">KARI</shortName>
            <ecNumber evidence="8">1.1.1.86</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Acetohydroxy-acid isomeroreductase</fullName>
            <shortName evidence="8">AHIR</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Alpha-keto-beta-hydroxylacyl reductoisomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ilvC</name>
        <name evidence="12" type="ORF">RPIT_07960</name>
        <name evidence="13" type="ORF">SAMN05428934_11332</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22068"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2-hydroxy-3-oxobutanoate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:13493"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49256"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 9">Belongs to the ketol-acid reductoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.86" evidence="8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07960"/>
    <dbReference type="EnsemblBacteria" id="AQP44747">
        <property type="protein sequence ID" value="AQP44747"/>
        <property type="gene ID" value="RPIT_07960"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16604">
        <property type="protein sequence ID" value="SDZ16604"/>
        <property type="gene ID" value="SAMN05428934_11332"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07960"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00056"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004455">
        <property type="term" value="F:ketol-acid reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00435">
        <property type="entry name" value="IlvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013023">
        <property type="entry name" value="KARI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000506">
        <property type="entry name" value="KARI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013116">
        <property type="entry name" value="KARI_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014359">
        <property type="entry name" value="KARI_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371">
        <property type="entry name" value="PTHR21371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01450">
        <property type="entry name" value="IlvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07991">
        <property type="entry name" value="IlvN"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="8" id="KW-0521">NADP</keyword>
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    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="2"/>
            <end position="182"/>
        </location>
    </feature>
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        <location>
            <begin position="183"/>
            <end position="328"/>
        </location>
    </feature>
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        <location>
            <position position="108"/>
        </location>
    </feature>
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        <location>
            <begin position="25"/>
            <end position="28"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
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        <location>
            <position position="48"/>
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        <ligand>
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        </ligand>
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        <location>
            <position position="51"/>
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        <ligand>
            <name>NADP(+)</name>
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        </ligand>
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        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
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        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
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        <location>
            <position position="191"/>
        </location>
    </feature>
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        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
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        <location>
            <position position="227"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
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        <location>
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        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:18420"/>
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        </location>
        <ligand>
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        </ligand>
    </feature>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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        </source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
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        <source>
            <dbReference type="PROSITE" id="PS51851"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP44747.1"/>
        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="342" mass="37111" checksum="B27764991FF427A9" modified="2017-04-12" version="1">MAEMFYDNDADLSIIQGRSVAVIGYGSQGHAHALNLRDSGVDVRVGLRPGSSSAAKAEAEGLRVLPVAEAVEEADLIMILAPDQVQRKVYAEEIEPHLTKGDALFFAHGFNIRFGYITPPEGVDVCMVAPKGPGHLVRREYANGRGVPAIIAVEKDETGNAWPLALSYAKAIGALRAGGIKTTFTEETETDLFGEQAVLCGGASALVQAGFETLVEAGYQPEVAYFECLHELKLIVDLMYEGGIAKQRWSVSDTAEYGDYVSGPRVIDERVKENMKAVLTDVQNGAFAKRFIDDQDAGAPEFKELRAKGEAHPIEETGRELRKLMSWVKTDDTDYVEGSAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF82</accession>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
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    </dbReference>
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    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="120" mass="12976" checksum="556C7636569D2ACF" modified="2017-04-12" version="1">MNKRATLPGASELFRPTKGAPDPVAPQPAEPPPPKSEPKRAEAETPAGGATGRVKHDHKITVYFSEDELNALEDANLELRRTHGIRVDRGRIVRMAVARAIADLAANGADSHLVSELRQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
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    <name>A0A1Q2CFC4_9ACTN</name>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="6" type="ORF">SAMN05428934_12011</name>
    </gene>
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        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    </organism>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ22312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08435"/>
    <dbReference type="EnsemblBacteria" id="AQP44819">
        <property type="protein sequence ID" value="AQP44819"/>
        <property type="gene ID" value="RPIT_08435"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ22312">
        <property type="protein sequence ID" value="SDZ22312"/>
        <property type="gene ID" value="SAMN05428934_12011"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08435"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
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        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="8"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="134"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="134"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDZ22312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="234" mass="25687" checksum="55AE8BDB6934414C" modified="2017-04-12" version="1">MDNVREARVLVVDDERALAGVVASYLKKEGFTPTLAHTGPESVAAAEELDPDVVILDLGLPGMDGVEVCRRIRSFSDCYVLMLTARADEVDKINGFAAGADDYLTKPFSPRELVARVNAVLRRPRESSLAEAPTAPRQFGPLRVLADGREVWVGNAQISLTRTEFDILDVLSARPQLAMSRRQIIEAVWGPGWVGDDHIVDVHVANLRKKLDDPPTQPRYVLTVRGVGYRMGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFC9</accession>
    <name>A0A1Q2CFC9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08530"/>
    <dbReference type="EnsemblBacteria" id="AQP44832">
        <property type="protein sequence ID" value="AQP44832"/>
        <property type="gene ID" value="RPIT_08530"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08530"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012569089" evidence="1">
        <location>
            <begin position="21"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="495" mass="51867" checksum="5FAFA5011577F552" modified="2017-04-12" version="1">MALPLLAGLAFSLVPPTASADQSDAARASSAISWLSDNSGDSGMLESYPGTGDPGLTLDAVIAAVAAGAPSAIIADWLEAVEPVFKERAIYDAGQGLTRHTGLIAKALFALTAAGDDPATYAGLDLRELTEDSLNHGAEPGWAGAPFGRDSVNAFGQAFVMLGLAATGDLPSSTVAFVSSKQCTDGGFPLYFTAGQSCAQAGSKSDPDGTALLIMALRAAQADGIGSSQAPLTKAVDWLAGMQRPNGSYYGAVPFTAVENTNSSGLAAAALAGLKPTHVARVGDWVAGLQLSSGPDAGAIAYSQADFDGHDATTPLGISRGTWLRATTQGLSAFVPRSFHDLLASEPEPEDDFVRTAPYTLPGEHIVNGRRWLTTCEPYSQTERCRTNIWASVVELRSGKYQVVQGWAFNNLTYLPSARSLWVNNPLGYKNLEGWTGDDGRRWKTDCDSAATGSNGCRSYAEVTVVSATPRPAGGYTFSKSNTFVFNNIVLFRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFD6</accession>
    <name>A0A1Q2CFD6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Copper-translocating P-type ATPase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">Cu2+-exporting ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_08445</name>
        <name evidence="10" type="ORF">SAMN05428934_12013</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000020">
        <property type="protein sequence ID" value="SDZ22351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08445"/>
    <dbReference type="EnsemblBacteria" id="AQP44821">
        <property type="protein sequence ID" value="AQP44821"/>
        <property type="gene ID" value="RPIT_08445"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ22351">
        <property type="protein sequence ID" value="SDZ22351"/>
        <property type="gene ID" value="SAMN05428934_12013"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08445"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="151"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="330"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="647"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="671"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDZ22351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="711" mass="74528" checksum="8627BAA9D890E89E" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFF0</accession>
    <name>A0A1Q2CFF0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_08155</name>
        <name evidence="4" type="ORF">RPIT_11515</name>
        <name evidence="5" type="ORF">SAMN05428934_1281</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000028">
        <property type="protein sequence ID" value="SDZ23924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44775">
        <property type="protein sequence ID" value="AQP44775"/>
        <property type="gene ID" value="RPIT_08155"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45347">
        <property type="protein sequence ID" value="AQP45347"/>
        <property type="gene ID" value="RPIT_11515"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ23924">
        <property type="protein sequence ID" value="SDZ23924"/>
        <property type="gene ID" value="SAMN05428934_1281"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08155"/>
    <dbReference type="KEGG" id="tfl:RPIT_11515"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ23924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="386" mass="40480" checksum="F990E1D3812B5712" modified="2017-04-12" version="1">MNDKLSDAFKSVIPEPPPTTGWVAGARRKRRNTRLAISGVAAAAVVALAIPVALNLPSVREPLVASPAPTPSATASSEPTQTPSVAPTQTSSPEPTIALTDIPSPDPVESPGAPSEPGPTLEPAGSDVPGSWACYNEDGRAPLLNANTGEDLPTGVGRAFLCGDGHEGFGVVGPLDPLVIEPDRIIELFEAQPEYVEVPDCGYEASDPYRIVLEYLNGDKWIISGYGEECQPLTDGTTQKAGEGFRDKVVALWQEQRAAVSPPAPPAATDALNCAPAQYPMIPMTLGDATAGIFCSQLDQEDPVEKVVLAPELVDRLVQAATSEAVAGYPEAAPGEASGTLILTNGWGDIFPVMRHGDQYAYVGDSEMMVWTPQDELAQALDNAFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFG5</accession>
    <name>A0A1Q2CFG5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative flippase GtrA (Transmembrane translocase of bactoprenol-linked glucose)</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Sugar translocase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_08675</name>
        <name evidence="9" type="ORF">SAMN05428934_10745</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GtrA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08675"/>
    <dbReference type="EnsemblBacteria" id="AQP44854">
        <property type="protein sequence ID" value="AQP44854"/>
        <property type="gene ID" value="RPIT_08675"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97166">
        <property type="protein sequence ID" value="SDY97166"/>
        <property type="gene ID" value="SAMN05428934_10745"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08675"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007267">
        <property type="entry name" value="GtrA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04138">
        <property type="entry name" value="GtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="GtrA" evidence="7">
        <location>
            <begin position="17"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY97166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="186" mass="21127" checksum="9BCBB43FCB2413AA" modified="2017-04-12" version="1">MRALFDRYGKTLGQFIKFAFVGGSGVLVNMLVLVIMNKLNGGSQNAQNIIWSIPNTPYNVRFTAIGWIVPFLVANLWNFQLNRWWTFKSSKHAGWWREFWPFLAVGSVAAAVGLALKLLMTNPTSPLYLPEPYFNEARGLQSREYWSQLIAIMLTLPINFLVNKFWTFRAIRGRRLTASVPPGVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFM1</accession>
    <name>A0A1Q2CFM1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Energy-dependent translational throttle protein EttA</fullName>
            <ecNumber evidence="7">3.6.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Translational regulatory factor EttA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ettA</name>
        <name evidence="12" type="ORF">RPIT_09020</name>
        <name evidence="13" type="ORF">SAMN05428934_107117</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="7">Associates with ribosomes and polysomes.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09020"/>
    <dbReference type="EnsemblBacteria" id="AQP44916">
        <property type="protein sequence ID" value="AQP44916"/>
        <property type="gene ID" value="RPIT_09020"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98577">
        <property type="protein sequence ID" value="SDY98577"/>
        <property type="gene ID" value="SAMN05428934_107117"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09020"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045900">
        <property type="term" value="P:negative regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00847">
        <property type="entry name" value="EttA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022374">
        <property type="entry name" value="EttA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43858">
        <property type="entry name" value="PTHR43858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03719">
        <property type="entry name" value="ABC_ABC_ChvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="2 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="6"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="324"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Arm" evidence="7">
        <location>
            <begin position="94"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="540"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="283"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <begin position="356"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP44916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY98577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="559" mass="62350" checksum="0236C32B8FB622C8" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFN0</accession>
    <name>A0A1Q2CFN0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase sigma-70 factor, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_09005</name>
        <name evidence="8" type="ORF">SAMN05428934_107114</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09005"/>
    <dbReference type="EnsemblBacteria" id="AQP44913">
        <property type="protein sequence ID" value="AQP44913"/>
        <property type="gene ID" value="RPIT_09005"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98518">
        <property type="protein sequence ID" value="SDY98518"/>
        <property type="gene ID" value="SAMN05428934_107114"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09005"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="16"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="97"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY98518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="163" mass="18370" checksum="74A6083317D6EEF1" modified="2017-04-12" version="1">MDEAQFDHLYTTRFNAIVGQIYAMCGNLTEAQDCVQEAFIRAWDHRSKLDPTGHPEAWVRTTAYRLAVSRWRRATKALRPPDRALQHPVPSEPTPDRVAIADALRQLPEKQRRAIVLHHLCDMTVAEVAAETGSPTGTIKAQLVRGRETLARLLNSDLEARHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFR9</accession>
    <name>A0A1Q2CFR9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09300</name>
        <name evidence="3" type="ORF">SAMN05428934_102449</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY61069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09300"/>
    <dbReference type="EnsemblBacteria" id="AQP44958">
        <property type="protein sequence ID" value="AQP44958"/>
        <property type="gene ID" value="RPIT_09300"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY61069">
        <property type="protein sequence ID" value="SDY61069"/>
        <property type="gene ID" value="SAMN05428934_102449"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09300"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_tran_28_C" evidence="1">
        <location>
            <begin position="225"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY61069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="328" mass="35906" checksum="E2720897F2BD4097" modified="2017-04-12" version="1">MIGYYVHHHGSGHVTRALTIARRLSSPVTGFSSLARPDGWPGEWIQLPDDRTDRPRDADAGGVLHWAPLGHPGYSRRMGALASWLSAERPRVMVVDVSVEVSLLARLLGVPVVVVAMRGDRTDRAHKAAYDAASALLAPWTEEHREPTWPVRWLDKTVHVGALSRFDGWEAPPGTRTRPDQVLVLWGAGGSEMGEEQIAAAQAATPDYRWTLRTPQHPSPDVWREMNEAAIVVTHGGQNAVAEVAAARRPAVVVAQERPHQEQLATAAALARRGVCTAVPRWPEPHHWPQLLATARERGGEGWASWNPGNGADVAARFLDRFTPEAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFS7</accession>
    <name>A0A1Q2CFS7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Abi-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_09390</name>
        <name evidence="2" type="ORF">SAMN05428934_102429</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY60527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09390"/>
    <dbReference type="EnsemblBacteria" id="AQP44971">
        <property type="protein sequence ID" value="AQP44971"/>
        <property type="gene ID" value="RPIT_09390"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY60527">
        <property type="protein sequence ID" value="SDY60527"/>
        <property type="gene ID" value="SAMN05428934_102429"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09390"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011664">
        <property type="entry name" value="Abi_system_AbiD/AbiF-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07751">
        <property type="entry name" value="Abi_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY60527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="330" mass="37697" checksum="D053C5AB9B4570E6" modified="2017-04-12" version="1">MHTAGVLFFLGPHVQIPPFLTVDQRVDYLYERGYFEPGSVTDEHAERLSRLNFHYFLGYARNYRALVGRRQVQVPRKTPDDVFRVIDLDAKVSALVHEGLRTAEWRLRAAAVERYCAKFAPANSYLQTTQYRATDAESPSRLVEGILLHIYRHDEPYVDECLREAATSKSMTKPRRYEAGCHGTCLVLAADLPLWAVVDSFSLGLLGQFVINCDKDTESPVWKAVAKDLEISAQVFETQVKSLAYLRNSVAHHARLWMRPTSDSAKKPRLFSNRLKNVHPKSMHWAFMNLATFLPKEQRFDFAQRVDTLTGSDAIYRHGITNVHETPKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFW6</accession>
    <name>A0A1Q2CFW6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09605</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09605"/>
    <dbReference type="EnsemblBacteria" id="AQP45011">
        <property type="protein sequence ID" value="AQP45011"/>
        <property type="gene ID" value="RPIT_09605"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09605"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="2">
        <location>
            <begin position="3"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="339" mass="36631" checksum="202D4D6A08FE03EF" modified="2017-04-12" version="1">MTGATGYVGSRLVPLLVERGHTVRTTASSPDREQPWWGDRVDTVVMDVLDADQVLAACEGVDAVYYLIHGMGKDDFEETDRQAATNVADAVRARGVQRVVYLSGIVPPVDDDELSEHIRSRREVERILIDSPATVVALRAAVILGSGSTSFEIIRQVSERMPVHTIPTWMDSMVQPIAVVDVLEALVGALDYEGQSRHFDVGGPDQLRYAQLLDAYTSEAGLERPQVDVPLLPTALVGTLVGSLTDVPRPTVEALVESLQHDMVSADNDFREALLPPGHRLVTLEEALRRSLAARSGSPQEADPMGPLPQDPVWASGGDDRPVAAKVVDAVTDLLPDAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG09</accession>
    <name>A0A1Q2CG09_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Formyltetrahydrofolate deformylase</fullName>
            <ecNumber evidence="3">3.5.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Formyl-FH(4) hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">purU</name>
        <name evidence="5" type="ORF">RPIT_09805</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(6S)-10-formyltetrahydrofolate + H2O = (6S)-5,6,7,8-tetrahydrofolate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19833"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="EC" id="3.5.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; IMP biosynthesis via de novo pathway; formate from 10-formyl-5,6,7,8-tetrahydrofolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PurU family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.10" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09805"/>
    <dbReference type="EnsemblBacteria" id="AQP45044">
        <property type="protein sequence ID" value="AQP45044"/>
        <property type="gene ID" value="RPIT_09805"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09805"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008864">
        <property type="term" value="F:formyltetrahydrofolate deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016742">
        <property type="term" value="F:hydroxymethyl-, formyl- and related transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04875">
        <property type="entry name" value="ACT_F4HF-DF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01927">
        <property type="entry name" value="PurU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004810">
        <property type="entry name" value="PurU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044074">
        <property type="entry name" value="PurU_ACT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42706">
        <property type="entry name" value="PTHR42706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01575">
        <property type="entry name" value="FFH4HYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00655">
        <property type="entry name" value="PurU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="3" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="4">
        <location>
            <begin position="5"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="279" mass="30752" checksum="25F2865E9C8B54DB" modified="2017-04-12" version="1">MPQLVVTFDCPDRPGIVHAITGGIVAAGGNIAELQQFSSPDTGHFFTRIEVDGADRVRLTDAIARATEEFSARFRVDDAGRPTRTLILASKAGHCLNDLLFRWRGGDLPIDVVGIMANHAVLAPMAAFYDVPFKHRFVTAETKAAFEAEIQKFVVDNDIELVVLARYMQILSPELCEFLAGRAINIHHSFLPGFKGANPYRQAHTRGVKLIGATAHFVTSDLDEGPIIEQNVVRVDHSMDVAKLVRKGQAQESQTLAEAVRLFAEHRVIVDGDRTIVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG76</accession>
    <name>A0A1Q2CG76_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.117</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Tetrahydrodipicolinate N-succinyltransferase</fullName>
            <shortName evidence="4">THDP succinyltransferase</shortName>
            <shortName evidence="4">THP succinyltransferase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Tetrahydropicolinate succinylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dapD</name>
        <name evidence="6" type="ORF">RPIT_10215</name>
        <name evidence="7" type="ORF">SAMN05428934_102262</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + succinyl-CoA = (S)-2-succinylamino-6-oxoheptanedioate + CoA</text>
            <dbReference type="Rhea" id="RHEA:17325"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15685"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="EC" id="2.3.1.117"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (succinylase route): step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.117" evidence="4"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10215"/>
    <dbReference type="EnsemblBacteria" id="AQP45119">
        <property type="protein sequence ID" value="AQP45119"/>
        <property type="gene ID" value="RPIT_10215"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55895">
        <property type="protein sequence ID" value="SDY55895"/>
        <property type="gene ID" value="SAMN05428934_102262"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10215"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00019"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008666">
        <property type="term" value="F:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02122">
        <property type="entry name" value="DapD_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019875">
        <property type="entry name" value="DapD_actinobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032784">
        <property type="entry name" value="THDPS_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038361">
        <property type="entry name" value="THDPS_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026586">
        <property type="entry name" value="Type2_DapD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14789">
        <property type="entry name" value="THDPS_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03535">
        <property type="entry name" value="DapD_actino"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="4" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="THDPS_M" evidence="5">
        <location>
            <begin position="101"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Succinyl-CoA binding" evidence="4">
        <location>
            <begin position="248"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-anhydride intermediate" evidence="4">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>ligand shared between trimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>ligand shared between trimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>succinyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>succinyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>succinyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>succinyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>succinyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>succinyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY55895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="308" mass="32759" checksum="24DEDD0AF9914428" modified="2017-04-12" version="1">MTTRTAWAWGLATVHTTGSVLDAWFPEPQLGSDVTDEPNSLLTEAQFVDEIRQVETKVVRVEIELDEAPATVEDAYLRLHLLSARLVEPHGLNLTGIFGILPNNAWTTAGPVRIGDIPRVRLLLGARGQQLTVYGIDKFPRMVDYIAPSGVRIADADRVRLGAHLAEGTTVMHEGFVNFNAGTLGTSMVEGRISAGVVVADGTDVGGGASIMGTLSGGGQEVIRLGERCLLGANSGVGISLGDDCVVEAGLYVTAGTKVELSDGRVVKARELSGQNDLLFLRDSQTGKVVARHRRGSKVELNSELHAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGF8</accession>
    <name>A0A1Q2CGF8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10580</name>
        <name evidence="3" type="ORF">SAMN05428934_102189</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY53767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10580"/>
    <dbReference type="EnsemblBacteria" id="AQP45187">
        <property type="protein sequence ID" value="AQP45187"/>
        <property type="gene ID" value="RPIT_10580"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY53767">
        <property type="protein sequence ID" value="SDY53767"/>
        <property type="gene ID" value="SAMN05428934_102189"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10580"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY53767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="264" mass="27383" checksum="5DB4BBF3A7A16EBE" modified="2017-04-12" version="1">MTNVDLGPILDDLAAGRIDAKEASRRIEAAKKAAQPAGSGPAPEADTTHHGGPKAGGLARVSVTAVGRRVRIEGDPSVSTVIIDGPHVLRRVGTVLEVSSTGEFGPSFQGFSLIRPPRSLDDLRDIGLGKELAIRVNPALIVDVEVTTGGLRTVGVPRLGRIRVTAGGSTLQDVQEVEDLLSQAGGVTVEGPISIGRSRIRTESGSLTVHLTEGANVTIRGESRLGRISWPGGGENVDEFVVGNGSARLDVNVVMGMATIKTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGH5</accession>
    <name>A0A1Q2CGH5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">UDP:flavonoid glycosyltransferase YjiC, YdhE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_10355</name>
        <name evidence="4" type="ORF">SAMN05428934_102234</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45145">
        <property type="protein sequence ID" value="AQP45145"/>
        <property type="gene ID" value="RPIT_10355"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55152">
        <property type="protein sequence ID" value="SDY55152"/>
        <property type="gene ID" value="SAMN05428934_102234"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10355"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030259">
        <property type="term" value="P:lipid glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033072">
        <property type="term" value="P:vancomycin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_28" evidence="2">
        <location>
            <begin position="3"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY55152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="444" mass="46040" checksum="4AADDFD7E60265E7" modified="2017-04-12" version="1">MRVALSALGSAGDVAPVVAIGSTLRMRGHDVRVVALEEYAPLVERAGLHLEAVPGGASTLWPDISWLRGLALAQPGVMYATMMTSFHSLAPHTNEALRRAADGVDVIVSGLVTRGAAAALAQATCADHLTVLFAPLLPASTTSSTALGLARGGRHVLRATSSAMWGLTRGLSAAHTADMTRRVGHRPESRSTLLLATSPVVSPPARQWPDGVEQVGWIPSVHGPAELPDEVREFLAGDGPTAVMTFGSCPVVSAQRDRRLFVEAARLAGVRLILTDGGAPVPGDDVLVTGPVSYEALLPQVSAVVHHGGAGTTYAALASGTPSVVVPHLGDQAYYARRVAELGAGPRGVPRWRVTAPILARRVLAALEMREGAQATARRLGPGTGARRIADLVEEGGSQPRRRERPTSQAARPASTPVQPSQLANGQRAADASPPASASRASST</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGL1</accession>
    <name>A0A1Q2CGL1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glucosidase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Glycosyl hydrolase family 63 C-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_11010</name>
        <name evidence="4" type="ORF">SAMN05428934_102101</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 63 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY51042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11010"/>
    <dbReference type="EnsemblBacteria" id="AQP45258">
        <property type="protein sequence ID" value="AQP45258"/>
        <property type="gene ID" value="RPIT_11010"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY51042">
        <property type="protein sequence ID" value="SDY51042"/>
        <property type="gene ID" value="SAMN05428934_102101"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11010"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004573">
        <property type="term" value="F:Glc3Man9GlcNAc2 oligosaccharide glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009311">
        <property type="term" value="P:oligosaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031335">
        <property type="entry name" value="Glyco_hydro_63_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004888">
        <property type="entry name" value="Glycoside_hydrolase_63"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10412">
        <property type="entry name" value="PTHR10412"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03200">
        <property type="entry name" value="Glyco_hydro_63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_63" evidence="2">
        <location>
            <begin position="573"/>
            <end position="882"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY51042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="899" mass="101503" checksum="09D231C17FEE7668" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGL7</accession>
    <name>A0A1Q2CGL7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycine/D-amino acid oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10995</name>
        <name evidence="3" type="ORF">SAMN05428934_102104</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY51147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45256">
        <property type="protein sequence ID" value="AQP45256"/>
        <property type="gene ID" value="RPIT_10995"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY51147">
        <property type="protein sequence ID" value="SDY51147"/>
        <property type="gene ID" value="SAMN05428934_102104"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10995"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="4"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY51147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="364" mass="38244" checksum="D8DE1DA1F837CCA0" modified="2017-04-12" version="1">MAHDVVVLGATVAGLTASRRLAAEGYDVVVLDPNLELRSAAIGHGVAAIGHASTVANMAHAYGLEAAREHVRRNIAALQEIRTTLPDHDTHTLRDQSLPGGDERETQEIAALYRSQGTQASVAGGPRDATLITEATCVDPAEYASALRTAAVGEGVQVVHGVTVTHLKRKEGVTRVGFRNNLAWARELGSITGAAVIDTLGVSPWGRVARVGPAQWVPVVRCVPGVPVTDVRLHATGPAWMVRPTTEGALVLGQKTSLSAIDESTIELEQWAAEALGAEWMETGRLAIDPSDHGRPVVGASAIPGGFYARGNGRGELMNGTASGYYLATLLLGDDAAPGNALPPLSRMRAYGSRLRRASHRPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH31</accession>
    <name>A0A1Q2CH31_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative multiple sugar transport system permease protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_11980</name>
        <name evidence="9" type="ORF">SAMN05428934_10679</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11980"/>
    <dbReference type="EnsemblBacteria" id="AQP45429">
        <property type="protein sequence ID" value="AQP45429"/>
        <property type="gene ID" value="RPIT_11980"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92387">
        <property type="protein sequence ID" value="SDY92387"/>
        <property type="gene ID" value="SAMN05428934_10679"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11980"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="323"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="404"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY92387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="439" mass="46202" checksum="8DEF0BBAFC5D39A7" modified="2017-04-12" version="1">MRALKQVFGGNLQQYTMALALIALVAVFDIISEGRMLTSSNFQNLISGNAYVLILAIGMVMVIVIGQIDLSVGSVAGFVGMSVAISIAQYGFPWWAGLLLGLLVGVVVGMWHGFWLAKMGIPGFITTLAGMMIFRGLVIWMSSSISVPVPSEFSFLGAGYLPEWGPAWTGLNNSTLLLGLLALAWFVYSELKRRGHAKARGAEIPMWVTITRLALIALVIGYVTWLFGSGRPGTSFPVPGLILVLLVIVYHVITQRTRFGRHIYAVGGNKAAAALSGVNTQRTYFLVMTNMSFLAAIAGILFIGRSTAAGPSDGTMWELDAIAAVFIGGAAVSGGIGTVVGSMIGGLVMAVLNSGLMLMGVGADQTQVIKGLVLLAAVAFDVYNKNQGKPSLIGTLMRNFGKKPDPAVQAPTRSAVVADSTTDVPVEGPAVDSRDTVPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH34</accession>
    <name>A0A1Q2CH34_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Multiple sugar transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_11955</name>
        <name evidence="7" type="ORF">SAMN05428934_10684</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11955"/>
    <dbReference type="EnsemblBacteria" id="AQP45424">
        <property type="protein sequence ID" value="AQP45424"/>
        <property type="gene ID" value="RPIT_11955"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92524">
        <property type="protein sequence ID" value="SDY92524"/>
        <property type="gene ID" value="SAMN05428934_10684"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11955"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="73"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="273"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="73"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY92524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="305" mass="34034" checksum="D430BBEE82102943" modified="2017-04-12" version="1">MLKRLRGRQGRNLWFLAFVAPFFLGLAAFVYVPIAWSAYLSFFDARNTVTPTKFVGLGNYAYLLQDKLFLNSLLVFAIFAIFIVPLTYVCSLGLALLLNNLKYGQAFFRSVFFIPTAVSYVIAAIIWRFVFFNGARFGMINSFIRSAGGDPVNWLGGGNNLYWVALVSVRLWLQVGFYMILFIAGLNQIPRETYEAAALDGASGWRLLRWITLPQLRAASVAVLMLLFINAFQAFDEFFNMLSSIGQYPPYGRPPLVHLYLIAFGGGQQDLGVGGAGTIILTAIIVVFGLGQNWVLGRNERRGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH36</accession>
    <name>A0A1Q2CH36_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12015</name>
        <name evidence="3" type="ORF">SAMN05428934_10672</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45436">
        <property type="protein sequence ID" value="AQP45436"/>
        <property type="gene ID" value="RPIT_12015"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92240">
        <property type="protein sequence ID" value="SDY92240"/>
        <property type="gene ID" value="SAMN05428934_10672"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12015"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY92240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="79" mass="7912" checksum="B478F1A23B5A1E83" modified="2017-04-12" version="1">MTDKRHLSDDEILTSDRNNPAGTVPDAHAGGELESTSDRNNPAGNVGHDGGDADGTDGDSTDVVDGDSTDGGDADATDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH46</accession>
    <name>A0A1Q2CH46_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_11700</name>
        <name evidence="2" type="ORF">SAMN05428934_106135</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11700"/>
    <dbReference type="EnsemblBacteria" id="AQP45380">
        <property type="protein sequence ID" value="AQP45380"/>
        <property type="gene ID" value="RPIT_11700"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93643">
        <property type="protein sequence ID" value="SDY93643"/>
        <property type="gene ID" value="SAMN05428934_106135"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11700"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY93643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="294" mass="30878" checksum="840A698AFFBDDFC1" modified="2017-04-12" version="1">MYPVLEVGGTHVTAALVDLAPPHVAHAERVEIDSSADAETLLKSFTAAVAGLGDEARAKPLVVAIPGPFDYDRGIGDFEGVAKFGSLRGVRVGDELARRLGSGSVTFLNDVTAYGIGQYELLGRPRRMVALTLGTGVGSVFLQDGSPVTAGPGVPPNGWVYLLEHDGRPIEETFSRRAIIAAHAAASGQELDVHEIADQARSGDPTAVHTLSAAYASLAETLAPYLIAFETDLLVVGGSIARSWDLILRWFEPSVMSHFHHLDVQAPRILPGAVGETAALIGAARYGAGAATRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH70</accession>
    <name>A0A1Q2CH70_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC transporter substrate-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Multiple sugar transport system substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_11950</name>
        <name evidence="4" type="ORF">SAMN05428934_10685</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11950"/>
    <dbReference type="EnsemblBacteria" id="AQP45423">
        <property type="protein sequence ID" value="AQP45423"/>
        <property type="gene ID" value="RPIT_11950"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92546">
        <property type="protein sequence ID" value="SDY92546"/>
        <property type="gene ID" value="SAMN05428934_10685"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11950"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544485" evidence="2">
        <location>
            <begin position="23"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY92546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="434" mass="45914" checksum="BE4A02314BB9B4EE" modified="2017-04-12" version="1">MNLNRRTLLLAGGGLSAAAVLAACGNNNPLSSESPTGTAPSGSPSGSAPASDVTLTQWYHEYGEAGVKEAVERYAAEYTGAKVEVKWTPGEYAKILAAQLLTDDVPDVFEVEQGGSLDMIRSGQLEPLNDIIDPVKDQFNPAVIKRFTFEDKIYGVPQTIDMQLLYYRPSLLEAKNIAVPTTFEELVAAANAVKTSDIGGFFAGNDGGVGVLGTILLWASGHEQLNEERTEAAFLTDDFYNALVAYRDFSKSGGVLQAASAEWYDPGAFVNGEAAFQWGGLWSLPAIKEAHGDDVGVIAFPAIGAKGRPVVPFGAFGACVAAKGKNVQAAKDFVKWLWIDQEDKQVDFSNAYGTHVPAKVALVPKADKLADGAGADAAKYVAENGFTNDIMWSGALGDAFNAAVSNVIKNDADPEAEFAGFAEKAKTELAKLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH92</accession>
    <name>A0A1Q2CH92_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DO-GTPase2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12050</name>
        <name evidence="3" type="ORF">SAMN05428934_10665</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12050"/>
    <dbReference type="EnsemblBacteria" id="AQP45443">
        <property type="protein sequence ID" value="AQP45443"/>
        <property type="gene ID" value="RPIT_12050"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92077">
        <property type="protein sequence ID" value="SDY92077"/>
        <property type="gene ID" value="SAMN05428934_10665"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12050"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045528">
        <property type="entry name" value="DO-GTPase2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19993">
        <property type="entry name" value="DO-GTPase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DO-GTPase2" evidence="1">
        <location>
            <begin position="98"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY92077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="398" mass="44089" checksum="34F74439AC532A85" modified="2017-04-12" version="1">MSQCPQCFTPIGATPALYVCKGSCPEIIDTQYTAWFGRERRSRPLTVVTAPDDPKLAKRWRAEEKISCRKCKQSAVRVCPTCHFVLPSGWMDARVVCVALAGPRSTGKSVYIAVMVQKLERLVESLRSKLTPVGSTRHTYDENYHKTLIVARQMMEPTGSATTGNYQQEPLIYSLGRIGRMEQESYLVLRDVAGEDLERNHRESYLQFFRNASMVLFHFDPTQIAEVRNELKGHLTDLNDVGIRPGAVLDNLLDILGAARPRLAVVLSKFDTLQLIGEGGATGDQGSAGSWTKRLANVGAAFNREAPEDMRYDEADGQVLHEEARSLLTMLGAVGIVNQLERPAKGGPMIHRFFVSSALGEPPLNRRTNPRGIAPFRVLDPIKWVLAAEGVIERVGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH97</accession>
    <name>A0A1Q2CH97_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized conserved protein, contains PQ loop repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_12370</name>
        <name evidence="4" type="ORF">SAMN05428934_1062</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY90697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12370"/>
    <dbReference type="EnsemblBacteria" id="AQP45498">
        <property type="protein sequence ID" value="AQP45498"/>
        <property type="gene ID" value="RPIT_12370"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY90697"/>
        <property type="gene ID" value="SAMN05428934_1062"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12370"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
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        <property type="entry name" value="Uncharacterised_HI1736/YgjV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10688">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="67"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY90697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="201" mass="21783" checksum="4DA832AF0A475DF6" modified="2017-04-12" version="1">MDWVELVGYIASAFVVLSFAMSSIVKIRSISLVGSAFYVAYGILIGSIPIILANGTIVVFHLVALSKEFSRKTELGATPIAPDAPFLADFLHSHTADIAKTQPEYEQAPSDTAFVLMREGMPAGAVMGNRDGDTLHLNLDYVLPAYRDSQLGKWIYGSRSSALRAHGIRKVTASPTTEVHRSYLGHMGFEPDGDRLVKALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH99</accession>
    <name>A0A1Q2CH99_9ACTN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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        <name evidence="2" type="ORF">SAMN05428934_10668</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
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    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP45440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY92141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12035"/>
    <dbReference type="EnsemblBacteria" id="AQP45440">
        <property type="protein sequence ID" value="AQP45440"/>
        <property type="gene ID" value="RPIT_12035"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92141">
        <property type="protein sequence ID" value="SDY92141"/>
        <property type="gene ID" value="SAMN05428934_10668"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12035"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012548">
        <property type="entry name" value="DUF1704"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY92141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="389" mass="42915" checksum="B4203261671F5DA8" modified="2017-04-12" version="1">MTPNPLAKLDQAIDLQLSQLSTSFRFILDVTPIDAEDVKEAFLAGDVVEPTFTYREYIIDPEVLQTVLHSIDVGRVQDTTVASLLRNKHRELDLQLSMLRCRNSADFRNLSIELFGGVHNDLLTAAESILERVEPAPWAGERLTAEQFLALANEELDYYRELEPDVDIHAEVRHDSTGVMVSDNLLIIGPETLVAANRANALVQHEVGTHLVTQVNGSHQPLQVMGTGLAGYDETQEGVAVLSEIAAGELTASRLRQLAGRVVTVHRMLVGHTFRECWEGLVDDGFSRGGGFTTVMRVFRSGGLTKDACYLRGLLDLLDHLRHGGEIDAFFLGKFSLQDLPLIEELNARGVLHEPVILPRWFDSSAGRDRLDAAAHLTDPVDLIQGEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHA8</accession>
    <name>A0A1Q2CHA8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC transporter substrate-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Peptide/nickel transport system substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_12420</name>
        <name evidence="4" type="ORF">SAMN05428934_104201</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY80575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12420"/>
    <dbReference type="EnsemblBacteria" id="AQP45508">
        <property type="protein sequence ID" value="AQP45508"/>
        <property type="gene ID" value="RPIT_12420"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY80575">
        <property type="protein sequence ID" value="SDY80575"/>
        <property type="gene ID" value="SAMN05428934_104201"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12420"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544489" evidence="1">
        <location>
            <begin position="31"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="118"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY80575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="554" mass="59074" checksum="E1034B2B28AEE415" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHB5</accession>
    <name>A0A1Q2CHB5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_12425</name>
        <name evidence="6" type="ORF">SAMN05428934_104200</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY80542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12425"/>
    <dbReference type="EnsemblBacteria" id="AQP45509">
        <property type="protein sequence ID" value="AQP45509"/>
        <property type="gene ID" value="RPIT_12425"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY80542">
        <property type="protein sequence ID" value="SDY80542"/>
        <property type="gene ID" value="SAMN05428934_104200"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12425"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="7"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY80542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="253" mass="27180" checksum="E8211B73CFCE3213" modified="2017-04-12" version="1">MSGSREPQRLRQTIQAVKEHILTQGLKPGDPMPTEVQLVEELGVSRSNLREAVRTLVALDILEVRHGTGTFVGQMSMRPLVEGLTFKGVVLPGDDFKTLRQIVEVRQALDLALAPEIVAHWAGRDGAALYALCDAMAAQKARNDTFAAEDRAFHLTLTDVLDNTLYGQLVAAFWDVHTVVAPRLGVPTPRDIADTVAAHQAMCDAAIAGELETYQEAVLSHYAPLMRVLTGGAVSSDDAAGDGYGLEEVASPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHF2</accession>
    <name>A0A1Q2CHF2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glucokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_12395</name>
        <name evidence="2" type="ORF">SAMN05428934_104206</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY80717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12395"/>
    <dbReference type="EnsemblBacteria" id="AQP45503">
        <property type="protein sequence ID" value="AQP45503"/>
        <property type="gene ID" value="RPIT_12395"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY80717">
        <property type="protein sequence ID" value="SDY80717"/>
        <property type="gene ID" value="SAMN05428934_104206"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12395"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY80717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="309" mass="31051" checksum="90B5D4DB1DC4B213" modified="2017-04-12" version="1">MSHVVGVDLGGTKTAAARVAPDGTLGEIVSAPTPALRGGQAVLDVVADLVRRVGGDDTVGLGVGTAGVVDATVGRIISATDTFSDWVGTDVAGGLRQRLSWSDRPIEVINDVDAHALGEQWLGAARDHGSVLMVAVGTGVGGAVVLDGRLWTGAHHVAGEIGHVPTPGAEGLYCACGRPGHLEAVAAGPAIERMYGVDGVDGRAIMARAEAGEEKALAVVERAASSLGRAIAGLVTVLDPACVVIGGGVALAGDVWWGPLRRTIRDELVPILADIPVLPAAAGPSAAILGAAKRALDSVAAHPHQRSLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHF7</accession>
    <name>A0A1Q2CHF7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12355</name>
        <name evidence="3" type="ORF">SAMN05428934_1065</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KHG/KDPG aldolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY90762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12355"/>
    <dbReference type="EnsemblBacteria" id="AQP45495">
        <property type="protein sequence ID" value="AQP45495"/>
        <property type="gene ID" value="RPIT_12355"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY90762">
        <property type="protein sequence ID" value="SDY90762"/>
        <property type="gene ID" value="SAMN05428934_1065"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12355"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000887">
        <property type="entry name" value="Aldlse_KDPG_KHG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30246">
        <property type="entry name" value="PTHR30246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01081">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY90762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="207" mass="21097" checksum="6DA841307450DF85" modified="2017-04-12" version="1">MDQPLRGLIVCLPDASLDDYIGAVEVLVQEGFSALALPASAEAFGDVAAIFGARITVGASRVALPQQIHAAADAGARFILADDTGSAIADAAAERGLPCYLPAMTPTEVRAVLEMPVAGALIFPADVVGHAMAARFQQLGLSDRVVPLGGIGAYAAGEWSKAGAPAVCVDTALLGDALTGGSLSSLRDRCGSFRSVEQRMLESKSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHW7</accession>
    <name>A0A1Q2CHW7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fructosamine-3-kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13340</name>
        <name evidence="3" type="ORF">SAMN05428934_10419</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the fructosamine kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY75480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13340"/>
    <dbReference type="EnsemblBacteria" id="AQP45673">
        <property type="protein sequence ID" value="AQP45673"/>
        <property type="gene ID" value="RPIT_13340"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY75480">
        <property type="protein sequence ID" value="SDY75480"/>
        <property type="gene ID" value="SAMN05428934_10419"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13340"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="PTHR12149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006221">
        <property type="entry name" value="Ketosamine-3-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY75480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="255" mass="26980" checksum="A017F2F94A312CCD" modified="2017-04-12" version="1">MRTFRKTGSRRAIATEAASLLWLADAGGAAVATLAEVGDTWLETLLLTPGTPSHESAADFGRRLAATHAAGADWWGQAPPGLDPDDLATANLPTPAAAEPTWRTFGEYYAEGRLRPYIDMAQGLGRGEAKALHAACDAVATGKFDSPQPALCGEVARIHGDLWSGNVVWADGRVGTLIDPCANGGHAETDLAELALFGSPHLADTIAGYEEVSPLADGWRERVPLHQLHMLLVHVVLFGGGYLTQALDVARELSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHY0</accession>
    <name>A0A1Q2CHY0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-oxoacid dehydrogenases acyltransferase (Catalytic domain)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13690</name>
        <name evidence="3" type="ORF">SAMN05428934_11161</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13690"/>
    <dbReference type="EnsemblBacteria" id="AQP45729">
        <property type="protein sequence ID" value="AQP45729"/>
        <property type="gene ID" value="RPIT_13690"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12739">
        <property type="protein sequence ID" value="SDZ12739"/>
        <property type="gene ID" value="SAMN05428934_11161"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13690"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="2-oxoacid_dh" evidence="1">
        <location>
            <begin position="226"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ12739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="288" mass="32862" checksum="95AD2998873D3EFE" modified="2017-04-12" version="1">MVSIGARAFRGRRDGRLIDDLPSTRRVVPHLMPTRLDAIVYYPQHLEVDVVMDWLDEVNRDRPAEERIRFFHVMLAALARLFHQRPELNRFISGRRTYEHRDISFAFTVKKALTDEADEVQARITFSGVDTVDEVRLMVDAALERARNHTRNESDILVSRLVKLPGPLLAAVAQTVWALDSVNRLPKMLQDAIPTYASAYLVNMGSLNAEAPFHHLYRRGTAGVFVSIGTIRPEPVVDADGEIVARRRVDVVYTVDERVTDGFYLVRSSHILQQMLNEPALLNQPTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI23</accession>
    <name>A0A1Q2CI23_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Deoxycytidylate deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13890"/>
    <dbReference type="EnsemblBacteria" id="AQP45762">
        <property type="protein sequence ID" value="AQP45762"/>
        <property type="gene ID" value="RPIT_13890"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13890"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015517">
        <property type="entry name" value="dCMP_deaminase-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11086">
        <property type="entry name" value="PTHR11086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="124" mass="13171" checksum="011FDF00E2F01C1E" modified="2017-04-12" version="1">MSLPSFDDLALDTARLWASRSADPKVQVGACLLDRWNRVVGVGYNGRAAGEPNERESLDQGHSGFIHAEVNALLAANWNGEGHTLFVTHERSYTETARADAGLPSGAQILRDAGLTVELGLAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI43</accession>
    <name>A0A1Q2CI43_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GDP-mannose 4,6-dehydratase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">UDP-glucose 4-epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_13780</name>
        <name evidence="3" type="ORF">SAMN05428934_11144</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ12411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13780"/>
    <dbReference type="EnsemblBacteria" id="AQP45743">
        <property type="protein sequence ID" value="AQP45743"/>
        <property type="gene ID" value="RPIT_13780"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ12411">
        <property type="protein sequence ID" value="SDZ12411"/>
        <property type="gene ID" value="SAMN05428934_11144"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13780"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ12411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="317" mass="33413" checksum="89A91A76075BBB18" modified="2017-04-12" version="1">MKVLVTGGAGFIGSNLARAMLAAGSFEEVRVLDDLSTGYAENLTGLDVAFTEGSILDMAALERVADGVDSIVHLAAIPSVPRSVANPRASHDANATGTLNVLEAARATGVEQVIVASSSSVYGSNPTLPKNEDDWTRPLSPYAVSKLATEGYAIAYQASYGLKTLPFRFFNVYGPGQAAGHAYAAVVPKFIDAALSGQALEIHGDGRQSRDFTFVADVCRVIMSAVSRRLSHPGPVNLAFNTNTTLLELISELEAQLGETVAKEFTDPRVGDVRASQADSLLLRELFPDVTPLPLADGLSATLAWYRGRIGLDTGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI58</accession>
    <name>A0A1Q2CI58_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_14110</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14110"/>
    <dbReference type="EnsemblBacteria" id="AQP45797">
        <property type="protein sequence ID" value="AQP45797"/>
        <property type="gene ID" value="RPIT_14110"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14110"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="204"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="264"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="477" mass="52363" checksum="EA6D6481977E28D4" modified="2017-04-12" version="1">MTAPATAFAPTATIRARIMWTMVLLAVASLITSGVVVAVLQDRNIHANVYAQLSRSKDELQVLASRGVDPATGAAFTGPSQLLQTYLQRTVIGPAEGELAFVDGRVAWVTEDAALRPENDEQLLAMVTPLATGNQIVIERMRTDQAHYYVLVAPVIFPNESGALVHVHDLDAAEAELRRTMTSYAVVALITIVVVVLLAWFAVGRLLKPIEQLREAAESIDERDLTSRVPVHGRDDLTALSVTINHMLDRVQRSVESQRRLLDDVGHELRTPITVVRGHMELIDPADPADVVQTRDLVIDEVDRMSVLVNDLLMLAKAGESDFVTPQWFDLATLTDQTFEKARTLGNRRWRLERVASAEAWFDPGRITQAWLQLAANAVKYSDEGTAITLGSALHRGEVFLWVKDEGIGIAPDQLETVRERFGRTREGASHAQGAGLGLSIVESIVRSHGGRLDIESREGEGSTFIIVFPLGPKEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI87</accession>
    <name>A0A1Q2CI87_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Coenzyme PQQ synthesis protein D (PqqD)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_13960</name>
        <name evidence="2" type="ORF">SAMN05428934_1116</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ11619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45770">
        <property type="protein sequence ID" value="AQP45770"/>
        <property type="gene ID" value="RPIT_13960"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ11619">
        <property type="protein sequence ID" value="SDZ11619"/>
        <property type="gene ID" value="SAMN05428934_1116"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13960"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008792">
        <property type="entry name" value="PQQD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041881">
        <property type="entry name" value="PqqD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05402">
        <property type="entry name" value="PqqD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ11619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="90" mass="9084" checksum="82A00C4A153C7934" modified="2017-04-12" version="1">MTTLYAQSTPIDALEVGGESLVLLPPDRLVRLSPIGTAIFAAAASPCSAETIAALVGEQFGPPEDGDTVAAVRQFCADLVEAGVLGVVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI90</accession>
    <name>A0A1Q2CI90_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14210</name>
        <name evidence="3" type="ORF">SAMN05428934_11224</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ14642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45814">
        <property type="protein sequence ID" value="AQP45814"/>
        <property type="gene ID" value="RPIT_14210"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ14642">
        <property type="protein sequence ID" value="SDZ14642"/>
        <property type="gene ID" value="SAMN05428934_11224"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14210"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544526" evidence="1">
        <location>
            <begin position="28"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ14642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="277" mass="30213" checksum="8400C2F088450619" modified="2017-04-12" version="1">MRKWLATLTATIAVAAGSIVASTSASALPLAPEPVLPVTGIPVPCATTHEYPADSSIEEIQAQLTANYGFKLAGSQWTDERRPSIKILWETLDAMECTTYRTDLLAKQGGNVGINAASISGYAWGDWSLTRTSYVTLDFSKFQRALDSGDEGRLTRLVAHELAHVRNSDRFENPEYWQVFKELYAREGRFSNYAGSKITETFADVVGYYVGRCALDNPYDTGEHDAYYDYAKTYIFGGKEFGPAPGATPDCALPAEGAEEPLPGEDAPLWLEGLAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI98</accession>
    <name>A0A1Q2CI98_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative pyruvate, phosphate dikinase regulatory protein</fullName>
            <shortName evidence="5">PPDK regulatory protein</shortName>
            <ecNumber evidence="5">2.7.11.32</ecNumber>
            <ecNumber evidence="5">2.7.4.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_14325</name>
        <name evidence="7" type="ORF">SAMN05428934_11247</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ADP + N(tele)-phospho-L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] = AMP + H(+) + N(tele)-phospho-L-histidyl/O-phospho-L-threonyl-[pyruvate, phosphate dikinase]</text>
            <dbReference type="Rhea" id="RHEA:43692"/>
            <dbReference type="Rhea" id="RHEA-COMP:10650"/>
            <dbReference type="Rhea" id="RHEA-COMP:10651"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:83586"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.32"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H(+) + N(tele)-phospho-L-histidyl/O-phospho-L-threonyl-[pyruvate, phosphate dikinase] + phosphate = diphosphate + N(tele)-phospho-L-histidyl/L-threonyl-[pyruvate, phosphate dikinase]</text>
            <dbReference type="Rhea" id="RHEA:43696"/>
            <dbReference type="Rhea" id="RHEA-COMP:10650"/>
            <dbReference type="Rhea" id="RHEA-COMP:10651"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:83586"/>
            <dbReference type="EC" id="2.7.4.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.32" evidence="5"/>
    <dbReference type="EC" id="2.7.4.27" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ15091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14325"/>
    <dbReference type="EnsemblBacteria" id="AQP45837">
        <property type="protein sequence ID" value="AQP45837"/>
        <property type="gene ID" value="RPIT_14325"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ15091">
        <property type="protein sequence ID" value="SDZ15091"/>
        <property type="gene ID" value="SAMN05428934_11247"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14325"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016776">
        <property type="term" value="F:phosphotransferase activity, phosphate group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00921">
        <property type="entry name" value="PDRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005177">
        <property type="entry name" value="Kinase-pyrophosphorylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026565">
        <property type="entry name" value="PPDK_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31756">
        <property type="entry name" value="PTHR31756"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03618">
        <property type="entry name" value="Kinase-PPPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="153"/>
            <end position="160"/>
        </location>
        <ligand>
            <name>ADP</name>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ15091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="295" mass="32438" checksum="E9476D55C60F114A" modified="2017-04-12" version="1">MSAEPLEIHIIADSTGESAARVARAAITQFPTREFSIVRHRKMNSTAALLGALESVKSTGRPTAVFFTLVNEELSLLVRNFCTDADIPYADLMTDAMHALERITGIEADQVAMRPPGVEAEYFVRMSAIDFAVRNDDGSLPEALRECDICLVGPSRSGKTPLSIYLAYMGYKAVNVPLVPGIKPPKELDELDRWRIVGLTMDAERLLKIRGERVRGMGGFGTKDGYADLAKIYDELDEIAKVHRRLGCPIIDTTGVAIEEAASRIVDIVDDRARRVGSRLRRPPGIVRPGSDFKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIE7</accession>
    <name>A0A1Q2CIE7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Xylulose kinase</fullName>
            <shortName evidence="1 2">Xylulokinase</shortName>
            <ecNumber evidence="1 2">2.7.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">xylB</name>
        <name evidence="5" type="ORF">RPIT_14740</name>
        <name evidence="6" type="ORF">SAMN05428934_10972</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + D-xylulose = ADP + D-xylulose 5-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10964"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17140"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.17"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the FGGY kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.17" evidence="1 2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14740"/>
    <dbReference type="EnsemblBacteria" id="AQP45906">
        <property type="protein sequence ID" value="AQP45906"/>
        <property type="gene ID" value="RPIT_14740"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05959">
        <property type="protein sequence ID" value="SDZ05959"/>
        <property type="gene ID" value="SAMN05428934_10972"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14740"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004856">
        <property type="term" value="F:xylulokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005998">
        <property type="term" value="P:xylulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02220">
        <property type="entry name" value="XylB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006000">
        <property type="entry name" value="Xylulokinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01312">
        <property type="entry name" value="XylB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 2 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 2" id="KW-0859">Xylose metabolism</keyword>
    <feature type="domain" description="FGGY_N" evidence="3">
        <location>
            <begin position="4"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="4">
        <location>
            <begin position="240"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="71"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <feature type="site" description="Important for activity" evidence="1">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDZ05959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="464" mass="48300" checksum="A03D679EBEC887E6" modified="2017-04-12" version="1">MALVAGVDSSTQSCKVLVVDADSGEIVRQGSASHPAGTEVHPDAWWSAFQEAAAAAEGLDDVEALSVGGQQHGMVVLDADGEVIRPALLWNDTRSADAAAALRLEFDQWAEVTGSLPLASFTNTKLRWLADAEPEGAARVAAVALPHDWLTWKIRGHRDLGELVTDRSDASGTGYFDSYRNEYRPDLLSLALRRPADDVVLPRVLGPWESVEGPGFVVGPGCGDNAGAALGLGMSAGEVSVSLGTSGVVAAVSANPVVDPSGQVNVFADATGQWLPLTATLNAARILDAAREMLGVDHEELSRLALQAEPGAGGLTLVPWFEGERTPNLPGAKASLLGATLGNFTRENLARAAVEGLLALMATGVDGIAQLGVEVTRVKLIGGASKSRAVREIAPSVLGVPIDVPASAEYVALGAARQAASALHGGHVDWAPRGVESYEADPRPEVLARYRDLSDRLISGMGWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIL5</accession>
    <name>A0A1Q2CIL5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hydrolase_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02420"/>
    <dbReference type="EnsemblBacteria" id="AQP45976">
        <property type="protein sequence ID" value="AQP45976"/>
        <property type="gene ID" value="RPIT_02420"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02420"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="45"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="318" mass="35147" checksum="C933A3D447531757" modified="2017-04-12" version="1">MGWAADVELSGYQAREFALPDEPTYAQEPEGSLVATLVRRNPPTRRQAVLYVHGWSDYFFQTHLADAMDDLGFDFYALELRRYGRSLRPQQLAGYIADLTDYYTELDLAVQELRDAGHEKIVLMGHSTGGLVTSLYASERPGTFAALVLNAPWLELQGNAVVRPATQPVVAAARAVAPTTALKLPDSGFYRRSISKADGGEWEYNLNLKGDPAFAVRVGWLAAILEGHAKVAAGLDIDCPVLVVIADRSDFRRTWDDALKLADIVLDVERIAVRAPKLGRHVTIAKFVDGMHDLVLSGPQVRAKVLDEYARFLRCYAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIU9</accession>
    <name>A0A1Q2CIU9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphoenolpyruvate--protein phosphotransferase</fullName>
            <ecNumber evidence="5">2.7.3.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">RPIT_05575</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl-[protein] + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:23880"/>
            <dbReference type="Rhea" id="RHEA-COMP:9745"/>
            <dbReference type="Rhea" id="RHEA-COMP:9746"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:64837"/>
            <dbReference type="EC" id="2.7.3.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.7.3.9" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05575"/>
    <dbReference type="EnsemblBacteria" id="AQP46037">
        <property type="protein sequence ID" value="AQP46037"/>
        <property type="gene ID" value="RPIT_05575"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05575"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008965">
        <property type="term" value="F:phosphoenolpyruvate-protein phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00367">
        <property type="entry name" value="PTS-HPr_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000032">
        <property type="entry name" value="HPr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035895">
        <property type="entry name" value="HPr-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006318">
        <property type="entry name" value="PTS_EI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001127">
        <property type="entry name" value="PTS_EIIA_1_perm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008731">
        <property type="entry name" value="PTS_EIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001020">
        <property type="entry name" value="PTS_HPr_His_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036618">
        <property type="entry name" value="PtsI_HPr-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05524">
        <property type="entry name" value="PEP-utilisers_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00381">
        <property type="entry name" value="PTS-HPr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00358">
        <property type="entry name" value="PTS_EIIA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00107">
        <property type="entry name" value="PHOSPHOCPHPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47831">
        <property type="entry name" value="SSF47831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55594">
        <property type="entry name" value="SSF55594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00830">
        <property type="entry name" value="PTBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01003">
        <property type="entry name" value="PTS_HPr_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01417">
        <property type="entry name" value="PTS_I_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51093">
        <property type="entry name" value="PTS_EIIA_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00371">
        <property type="entry name" value="PTS_EIIA_TYPE_1_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51350">
        <property type="entry name" value="PTS_HPR_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00369">
        <property type="entry name" value="PTS_HPR_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="9 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PTS EIIA type-1" evidence="12">
        <location>
            <begin position="25"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="HPr" evidence="13">
        <location>
            <begin position="171"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="AQP46037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="852" mass="89408" checksum="ED230C6CEFE1BCC2" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIX4</accession>
    <name>A0A1Q2CIX4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_03825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03825"/>
    <dbReference type="EnsemblBacteria" id="AQP46000">
        <property type="protein sequence ID" value="AQP46000"/>
        <property type="gene ID" value="RPIT_03825"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03825"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="348" mass="37354" checksum="65E38BA9DD13F531" modified="2017-04-12" version="1">MSAISETLDTFLTDQEALLDDVGALPMLEVAREATAGGKRLRPAYCYWSYVAAAGEPADDAALLAVASSLDLLHVSALVHDDLIDDSDTRRGVPAAHKRFEELHERQAGRGSREDFGRSSAILLGDLLLMWSIELADASGHPGLDLARPLLSVMRTEVTAGQFLDVAAQYRVAPATSYADELTVARRVLEYKSARYSIRRPAQIGAALAAADAAVQDALGEFGSVIGRAFQLRDDVLGVFGDPAVTGKPYGGDIREGKRTVLVLTALDDANQAQAAELSDLLGRHDLTDAEVDRAAAIIDESGARRHVESIIERSTDQALRVLEEASLTSEGRTALTELALRSVRRAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIX9</accession>
    <name>A0A1Q2CIX9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09075"/>
    <dbReference type="EnsemblBacteria" id="AQP46098">
        <property type="protein sequence ID" value="AQP46098"/>
        <property type="gene ID" value="RPIT_09075"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09075"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="114"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="348" mass="38073" checksum="D2006B48ADD5467C" modified="2017-04-12" version="1">MRAVEHDGNDDLIVLDRTDQTAAHGIYNLWFEHDRWAQLSAEITDRRPTRVARRITGTTSGFTPKAGDRASWSGIYYATPADAGLHTHDITITTPAGRFPAWRIDGDPSTWAIHIHGLGSTRAGTLRGVRVATELGYTSLVVSYRNTAEGPRVGTGRTTLGHTETTDVDEAIGYAVRRGAQQVVIFGWSMGAAIALQLADYPRHQGMIAALVLDSPVLNLTEVITTNCVPSGLPAAAGHLAIPCLTLHPLARALGLPGRIPLRSFDWTARAADLTTPTLNLHGTRDDSVPIRLSQALRDQRPDLVTLEAFDAHHTNPWNSHANHWHRCVRTWLTARVETPRCRQPATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIY1</accession>
    <name>A0A1Q2CIY1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Oxidored_molyb domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_07230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07230"/>
    <dbReference type="EnsemblBacteria" id="AQP46071">
        <property type="protein sequence ID" value="AQP46071"/>
        <property type="gene ID" value="RPIT_07230"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07230"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Oxidored_molyb" evidence="2">
        <location>
            <begin position="246"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="519" mass="54001" checksum="AA38C4EE239EDA7D" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIY4</accession>
    <name>A0A1Q2CIY4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">UvrABC system protein A</fullName>
            <shortName evidence="14">UvrA protein</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Excinuclease ABC subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">uvrA</name>
        <name evidence="17" type="ORF">RPIT_04165</name>
        <name evidence="18" type="ORF">SAMN05428934_101437</name>
    </gene>
    <organism evidence="17 19">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 19" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">RP1T</strain>
        </source>
    </reference>
    <reference evidence="18 20" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">RP1</strain>
        </source>
    </reference>
    <reference evidence="17" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Forms a heterotetramer with UvrB during the search for lesions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the ABC transporter superfamily. UvrA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY35223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04165"/>
    <dbReference type="EnsemblBacteria" id="AQP46010">
        <property type="protein sequence ID" value="AQP46010"/>
        <property type="gene ID" value="RPIT_04165"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY35223">
        <property type="protein sequence ID" value="SDY35223"/>
        <property type="gene ID" value="SAMN05428934_101437"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04165"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00205">
        <property type="entry name" value="UvrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004602">
        <property type="entry name" value="UvrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041552">
        <property type="entry name" value="UvrA_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041102">
        <property type="entry name" value="UvrA_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17755">
        <property type="entry name" value="UvrA_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17760">
        <property type="entry name" value="UvrA_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00630">
        <property type="entry name" value="uvra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 14" id="KW-0228">DNA excision</keyword>
    <keyword evidence="12 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11 14" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 14" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="2 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0677">Repeat</keyword>
    <keyword evidence="13 14" id="KW-0742">SOS response</keyword>
    <keyword evidence="8 14" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ABC transporter" evidence="16">
        <location>
            <begin position="603"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="14">
        <location>
            <begin position="738"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="26"/>
            <end position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14 15">
        <location>
            <begin position="639"/>
            <end position="646"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="AQP46010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="SDY35223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="938" mass="102220" checksum="8BF686D3FCE7E6E9" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIY7</accession>
    <name>A0A1Q2CIY7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LytR_cpsA_psr domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_09625</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LytR/CpsA/Psr (LCP) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09625"/>
    <dbReference type="EnsemblBacteria" id="AQP46108">
        <property type="protein sequence ID" value="AQP46108"/>
        <property type="gene ID" value="RPIT_09625"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09625"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004474">
        <property type="entry name" value="LytR_CpsA_psr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03816">
        <property type="entry name" value="LytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="116"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="LytR_cpsA_psr" evidence="4">
        <location>
            <begin position="181"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="429"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="440"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP46108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="499" mass="53008" checksum="93C38EC567E7DEC0" modified="2017-04-12" version="1">MTVPSPTPSAQQLHKRRAFGFVLMSALLPGSVQSFAGNRGVGRLAGRVYGAAAALVVLVGLGLWLVRGFTVGLLLTPSVTFALRIALWALFVGWLLLLMDSWRLARPLTMPRRPRLWLTITTILLVLAVGAFSSAVANALVAVENLGTVLPGGGERDQKAGRYNVLLLGADSAEHREGLRPDSINVASIDARTGRTVLFGLPRNLERVRFPKDSPLRDLYPEGYVCDGGACMLNGIYTLGQDQGDLYDARDPGLAALKEAIEETLGIELNYYAMVDMAGFTELIDAMGGIRLDIGKPVPIGGVSTRISGYIEPGENRLLDGYHALWFARSRAESSDYERMVRQKCVMAAMVNQLNPTTVAMKFVELSEAGANLVRTDVGTGHVMELAELALKAKDLKLASVNFTPPLIVAADPDFDLIRSTVAAKIAESERLDDRRSAPSASASPATVPTTSTVAASERPAATASSAVSQSDAPAAAQPSASGEPFTETADLAEVCSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJB0</accession>
    <name>A0A1Q2CJB0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14550"/>
    <dbReference type="EnsemblBacteria" id="AQP46192">
        <property type="protein sequence ID" value="AQP46192"/>
        <property type="gene ID" value="RPIT_14550"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14550"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="136" mass="15289" checksum="9B9DF7973AC80E0D" modified="2017-04-12" version="1">MQISPVRPDEREAVVALWNDTGLTRPWNDPHADLERALHGPNSTVFAAREGDRLVGTAMVGHDGHRAWVYYVAAAPERRGQGIGQALMAAAEGWARERDIPKLQFMVRDDNQDVLDFYAHLGYERQSVVVLGRRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJD8</accession>
    <name>A0A1Q2CJD8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HisKA_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_12610</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12610"/>
    <dbReference type="EnsemblBacteria" id="AQP46155">
        <property type="protein sequence ID" value="AQP46155"/>
        <property type="gene ID" value="RPIT_12610"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12610"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012817634" description="HisKA_3 domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="3">
        <location>
            <begin position="162"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP46155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="363" mass="38230" checksum="716A37466A9EE0A1" modified="2017-04-12" version="1">MISLAVTAVPLAGWHVAIVATAAAAQSAALLRRRRAPVAVLAIGTALLVLTTVFAGDPVATELPVSFMMYAVAAHRPARTTWASVAAVVGAVGATYVFTLRPLPTSAAPGWATATLTVSLLVAVALGLTMRAHRQQLEAEKERAQQLALERDQRAQLEVLTERERIAREMHDLVAHSVAVMVTLAHGASSAMDRNPDLAREALGELTRTGSEALRDMRRVLGLLRDGSQPDGAASQTPGALPDLLATFAKVGLPVRLDVTGEPPPSEPLLHHTVYRIVQECLTNVLRHAPGSDAVAVRIGWGEADVTIEVTNTGPVVSRVAGEQSGHGLRGLRERAAAFGGSVEAGPVEGGWRVRATLNHGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBH5</accession>
    <name>A0A1Q2CBH5_9ACTN</name>
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        <submittedName>
            <fullName evidence="2">EcsC protein family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00375</name>
        <name evidence="2" type="ORF">SAMN05428934_10529</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY84184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00375"/>
    <dbReference type="EnsemblBacteria" id="AQP43459">
        <property type="protein sequence ID" value="AQP43459"/>
        <property type="gene ID" value="RPIT_00375"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY84184">
        <property type="protein sequence ID" value="SDY84184"/>
        <property type="gene ID" value="SAMN05428934_10529"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00375"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024787">
        <property type="entry name" value="EcsC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12787">
        <property type="entry name" value="EcsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY84184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="230" mass="24114" checksum="E14F2AB8E10B394E" modified="2017-04-12" version="1">MSEQNVIAVAEGLTANVFHEILDIAIEGKGKLPGAKHAAKQLLTQRNDPEAAISRMVAQHIAMAGGQGFATNWGGFLLSLVTIPANLAAATFVQARLVAGIAHLRGYELSDPRVRTAILMVMLGPSANADLVSRGVLPSSPLVVATAPVFDARLDGQVSRALFDRAMNQMSGKRMGVWAAKRIPLVGGGVGAAVDGWSTSTIARHAMAEFPSRRPRLSQGSVEMGDAPNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBI4</accession>
    <name>A0A1Q2CBI4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LLM class F420-dependent oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Probable non-F420 flavinoid oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00450</name>
        <name evidence="3" type="ORF">SAMN05428934_10544</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY84603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00450"/>
    <dbReference type="EnsemblBacteria" id="AQP43473">
        <property type="protein sequence ID" value="AQP43473"/>
        <property type="gene ID" value="RPIT_00450"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY84603">
        <property type="protein sequence ID" value="SDY84603"/>
        <property type="gene ID" value="SAMN05428934_10544"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00450"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019945">
        <property type="entry name" value="F420_G6P_DH-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023907">
        <property type="entry name" value="Non-F420_Flavin_OxRdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03557">
        <property type="entry name" value="F420_G6P_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03885">
        <property type="entry name" value="flavin_revert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY84603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="319" mass="35470" checksum="CDFB5FBF68DBD60B" modified="2017-04-12" version="1">MTRIGFHASHEQIAPGQLLSDVQHAERMGFDMAMCSDHFAPWSERQGHSGYAWAWLGAALATTGLEFGCVSAPGQRYHPAVAAQKIATLAAMFPGRFWTALGSGEAMNESITGERWPAKHERVARLEECVDIIRRLLAGEEVSHQGLVTVDRARVWDRPDEQPLLITPAVSPESAERSARWADGLITVNQDPDTLREVIASYRGAGGRGRVALQLHLSWAPTLEEAEAIAFEQWRSNVFGAPLSWDIDSVTGFDAAAEHVTMESVQRSVRISERPEQHLEWIREYAEMGFDDVYLHFVGQEQGAFLDTFGSDVLPKCDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBR5</accession>
    <name>A0A1Q2CBR5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TIGR02646 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00870</name>
        <name evidence="3" type="ORF">SAMN05428934_105127</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00870"/>
    <dbReference type="EnsemblBacteria" id="AQP43549">
        <property type="protein sequence ID" value="AQP43549"/>
        <property type="gene ID" value="RPIT_00870"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86806">
        <property type="protein sequence ID" value="SDY86806"/>
        <property type="gene ID" value="SAMN05428934_105127"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00870"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="275"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP43549.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY86806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="658" mass="73140" checksum="FB1B3796CAD52AA6" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
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        <name type="scientific">Tessaracoccus flavus</name>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="gene ID" value="RPIT_01145"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01145"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="81" mass="9085" checksum="D77381FA9C6E8041" modified="2017-04-12" version="1">MGHRLVQCDAADTSAAGLASYRAALEDRFLMNDLKTLRRFPRLMEVPPPGVRDLPRAARDFMRGLFLLEGRGRASGRTKCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBY9</accession>
    <name>A0A1Q2CBY9_9ACTN</name>
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        <submittedName>
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        <name evidence="4" type="ORF">SAMN05428934_1085</name>
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        <name type="scientific">Tessaracoccus flavus</name>
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        <lineage>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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            <strain evidence="3 5">RP1T</strain>
        </source>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP43617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01280"/>
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    </dbReference>
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        <property type="gene ID" value="SAMN05428934_1085"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
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        <location>
            <begin position="65"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
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            <dbReference type="EMBL" id="AQP43617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ00980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="139" mass="15472" checksum="49920F4509883F84" modified="2017-04-12" version="1">MQRYLWLVVLVAGGLLAWSLRQEPLSALLAVLLTAAAAWWLSPLAHGTSRKHRDVIDLPDGERRVIVYWRPGCIFCERLRGGLGEDAKRVHWVNIWQDAEAAEFVRSVNDGNEVVPTVVIDGVAHTNPDPRAVRDALSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBZ9</accession>
    <name>A0A1Q2CBZ9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    <organism evidence="1 2">
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        <lineage>
            <taxon>Bacteria</taxon>
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    </organism>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="AQP43627"/>
        <property type="gene ID" value="RPIT_01345"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01345"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="119" mass="12113" checksum="1536D6C714B1E163" modified="2017-04-12" version="1">MPSGWRSFDADLLSAGDVGGIEGAPSGFADYVVARFADEDSAGCLLSAMTVTSVHPAGYVYGSENGSCGGSATLYAEVGGVWGVALAMQAMPECSALREAGIPEGLGIRCGHETGDREY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC23</accession>
    <name>A0A1Q2CC23_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Putative fluoride ion transporter CrcB</fullName>
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    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_01530</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tessaracoccus flavus</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10 11">RP1T</strain>
        </source>
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    <comment type="function">
        <text evidence="1 9">Important for reducing fluoride concentration in the cell, thus reducing its toxicity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
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    </comment>
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    </comment>
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        <location>
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            <end position="51"/>
        </location>
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        <location>
            <begin position="58"/>
            <end position="80"/>
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    <feature type="transmembrane region" description="Helical" evidence="9">
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            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
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            <dbReference type="ARBA" id="ARBA00004023"/>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007610"/>
        </source>
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            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP43656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="117" mass="11842" checksum="BC00F60AA03921B3" modified="2017-04-12" version="1">MVARAAVIFAGGFIGTAARVAVTEAIGHEAIALATVNLTGCLVIGLISGYFGPRVTLLRIFLAVGGVASFTSWSSLALQGVASPGAMILVVAETMVGIIVAGLGHLYAMKRLRRGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCE5</accession>
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        <submittedName>
            <fullName evidence="4">Peptidase family M23</fullName>
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        <name evidence="4" type="ORF">SAMN05428934_10140</name>
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    <organism evidence="3 5">
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    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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                <person name="Schumann P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
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                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY23513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02205"/>
    <dbReference type="EnsemblBacteria" id="AQP43771">
        <property type="protein sequence ID" value="AQP43771"/>
        <property type="gene ID" value="RPIT_02205"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY23513">
        <property type="protein sequence ID" value="SDY23513"/>
        <property type="gene ID" value="SAMN05428934_10140"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02205"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544416" evidence="1">
        <location>
            <begin position="24"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="382"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY23513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="487" mass="50908" checksum="6813B5654B8B7C41" modified="2017-04-12" version="1">MWKALAAIGAALTVPLAPILVFAGALTGPQVQTQTISATCAGWAGDTPVGIELDAGQMNRAALVYAAALETGVGAAGAVVGIATAMQESFLGAHPAAATPNEDGDVGLFQQRSLVGWYADGTTQQENLQILADDAYQARTFYLGHTTLSGWHIPGLTDIDGWQHMTVAQAAQAVQVSAYPDAYAKHEGIARSLVALFAGQPAGLANCGPVDPSLDCAPTGMASEQGQTPDALRVMRCIHSRWPQIRSLLGVRPGDPKDHGTGRAVDVMIPNYFSPAGITLGTEIAEWARANAAALGVTYIIWREHLWSTARADEGWRRCGQTASCYTGPDPSAAHLDHVHISVHGTQGTGTTSAAVGSVVLPVDQYRLTSRFGDTGPRWKKAHTGLDFAAPTGTPIKAVTDGTITRAGPAGAYGNLTTLTTADGTVIYYAHQSTTMVRVGQRVTAGTVIGRVGATGNVTGPHLHLEVRVGGIPTDPDRWFRSRGITP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCL3</accession>
    <name>A0A1Q2CCL3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_02610</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02610"/>
    <dbReference type="EnsemblBacteria" id="AQP43844">
        <property type="protein sequence ID" value="AQP43844"/>
        <property type="gene ID" value="RPIT_02610"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02610"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="8"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP43844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="211" mass="22750" checksum="380D146343501EA9" modified="2017-04-12" version="1">MAKKDVVLQVENLKKAYGPVTIVEGFSMKVHAGEAVALTGRNGAGKSTVLRCLVGADRPDEGTVTVNGIKVSETNARIRRDVATVIDDLDFFPDLSVVEHLDLLARAHGLEDPDDLVDEVLEEVQLVPQAGQLPSTLSSGQRRRLALATAFVRPRQLLVLDEPEQRLDVEGVQWLGERLKSDLAGGLAIVLASHEPALLEAIGARTIRLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCM8</accession>
    <name>A0A1Q2CCM8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Purine-nucleoside phosphorylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02785"/>
    <dbReference type="EnsemblBacteria" id="AQP43872">
        <property type="protein sequence ID" value="AQP43872"/>
        <property type="gene ID" value="RPIT_02785"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02785"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004731">
        <property type="term" value="F:purine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09006">
        <property type="entry name" value="PNP_EcPNPI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004402">
        <property type="entry name" value="DeoD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43691:SF2">
        <property type="entry name" value="PTHR43691:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00107">
        <property type="entry name" value="deoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="1">
        <location>
            <begin position="16"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="236" mass="24679" checksum="2A0FCCB4992A450B" modified="2017-04-12" version="1">MATPHIACEPGDIAPLVIMPGDPKRAERIAKTRMENVRLVSDVRGIGAWTGTLDGVEMTAMASGMGIPSISIYATELFSQFGVRRIVRVGTCGGISDDVKVRDVIVAASAHTNSAVSTIDLPGVTLSLAASFDMLRAAVDAARAGDRAVHVGSVYSSDFFYSSRSDIIPALDQLGTLGVEMEAAGLYACAMKHRAEALTVLTVSDHLKDGSGDLSPEERETLFQGALDAAIAGLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCN7</accession>
    <name>A0A1Q2CCN7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_02830</name>
        <name evidence="2" type="ORF">SAMN05428934_101166</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY27164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43879">
        <property type="protein sequence ID" value="AQP43879"/>
        <property type="gene ID" value="RPIT_02830"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY27164">
        <property type="protein sequence ID" value="SDY27164"/>
        <property type="gene ID" value="SAMN05428934_101166"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02830"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY27164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="101" mass="11710" checksum="21BBEC2BDAE211EB" modified="2017-04-12" version="1">MKRSGTSYSIERGWAFNNLTYLPFMTRAQWSANPLGYANSWKASDESLWRTECDTEVTGSNACRSYGWTTVYHALPKPGGGYTFGQDNQWVFNNMVMFRRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCQ8</accession>
    <name>A0A1Q2CCQ8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Enoyl-CoA hydratase/carnithine racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_02875</name>
        <name evidence="4" type="ORF">SAMN05428934_101175</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY27429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02875"/>
    <dbReference type="EnsemblBacteria" id="AQP43886">
        <property type="protein sequence ID" value="AQP43886"/>
        <property type="gene ID" value="RPIT_02875"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY27429">
        <property type="protein sequence ID" value="SDY27429"/>
        <property type="gene ID" value="SAMN05428934_101175"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02875"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY27429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="251" mass="26375" checksum="5CA1A6A2B2C41F0E" modified="2017-04-12" version="1">MGTVDVSRHGSIAVVTLNQPGKRNAMTDDMWRAVPTVMADLDRDVDVTAIVLTGAGESFCAGSDISSLDELGHAESPVNAELAIARSPKPVVAAIEGPCFGGGLELAVACDLRIASESATFSVPPARLGIVYPVSATQRMIDLMGPAVTKEMLLTAVQLDAARALRVGLVNRVVDHGNALPIALQLTEHMSGLSQLTIRASKEIVDGLVARDLSAETAIAWVSRAATGPDLAEGKRAFTERRAPVFSWRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCS8</accession>
    <name>A0A1Q2CCS8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsG</name>
        <name evidence="10" type="ORF">RPIT_02955</name>
        <name evidence="11" type="ORF">SAMN05428934_101192</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY27983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02955"/>
    <dbReference type="EnsemblBacteria" id="AQP43901">
        <property type="protein sequence ID" value="AQP43901"/>
        <property type="gene ID" value="RPIT_02955"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY27983">
        <property type="protein sequence ID" value="SDY27983"/>
        <property type="gene ID" value="SAMN05428934_101192"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02955"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00480_B">
        <property type="entry name" value="Ribosomal_S7_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_S5/S7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005717">
        <property type="entry name" value="Ribosomal_S7_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_S7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_S7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_S7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="PTHR11205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="SSF47973"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01029">
        <property type="entry name" value="rpsG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S7" evidence="9">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP43901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY27983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="156" mass="17395" checksum="D8BC46580C4DCBFC" modified="2017-04-12" version="1">MPRKGPAPKRPVAIDPVYGSPLVSQLVSKILLDGKKTVAQSIVYDALEGTRAKTGVDPVQTLKRALDNVKPSIEVKSRRVGGATYQVPIEVKPGRQNTLAMRWLVSFSRARREKTMTERLMNEILDASNGLGASVKRREDTHKMAEANRAFAHYRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCT0</accession>
    <name>A0A1Q2CCT0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutamine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_02990</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln)</text>
            <dbReference type="Rhea" id="RHEA:20121"/>
            <dbReference type="Rhea" id="RHEA-COMP:9662"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.18" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02990"/>
    <dbReference type="EnsemblBacteria" id="AQP43906">
        <property type="protein sequence ID" value="AQP43906"/>
        <property type="gene ID" value="RPIT_02990"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02990"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004819">
        <property type="term" value="F:glutamine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006425">
        <property type="term" value="P:glutaminyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004514">
        <property type="entry name" value="Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_L25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_L25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="SSF50715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00440">
        <property type="entry name" value="glnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="9">
        <location>
            <begin position="27"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1c_C" evidence="10">
        <location>
            <begin position="338"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP43906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="558" mass="63266" checksum="2608E87C6DE950AE" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCV6</accession>
    <name>A0A1Q2CCV6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_03255</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03255"/>
    <dbReference type="EnsemblBacteria" id="AQP43952">
        <property type="protein sequence ID" value="AQP43952"/>
        <property type="gene ID" value="RPIT_03255"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03255"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="77"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="165"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="212"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="78"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="303" mass="32832" checksum="4EAA5C712B38DBF8" modified="2017-04-12" version="1">MAARTRRARRPSAVVEGRLTPYLYILPAFLVYGMFLLYPLIRAGQFSLYDWPGFGASRFVGLGNYVDLMSDDRFLDAITHALTLIFFYSIMPLVVGLVLAAILRRGQVRGLSFFRVVIFMPQVIALVVVAVAWHQIYSPNGLLNDALDVVGLGHLARGWLGDPNLALPAVGMIGFWLSTGLVMLLLLAGMGRIPNDLYEAARLDGAGPVREFLAISLPSVKAEITTALVLTIIAALKTFDLVYVTTSGGPGTATTVPSYEVYNRAFNLKEVGSASAVAIVLTILVFGINVVISRIGEEKVVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD01</accession>
    <name>A0A1Q2CD01_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RDD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_03550</name>
        <name evidence="8" type="ORF">SAMN05428934_101311</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY31653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03550"/>
    <dbReference type="EnsemblBacteria" id="AQP44002">
        <property type="protein sequence ID" value="AQP44002"/>
        <property type="gene ID" value="RPIT_03550"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY31653">
        <property type="protein sequence ID" value="SDY31653"/>
        <property type="gene ID" value="SAMN05428934_101311"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03550"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010432">
        <property type="entry name" value="RDD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016795">
        <property type="entry name" value="UCP021697"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06271">
        <property type="entry name" value="RDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF021697">
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="RDD" evidence="6">
        <location>
            <begin position="22"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY31653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="142" mass="15084" checksum="6F31C5F09EDEDC95" modified="2017-04-12" version="1">MTDTPLSPGESIGLPAVGPGSLASWRSRVAAMIGDWAASMIVATLIFGSEVLVGNDWRSFMILTVYFVEASVLTALTGASFGQLIARIGIIRLDGQPLGWWRPVVRTALKCLVIPAIVIGAERRGLNDLLLGTVVVNRRPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD11</accession>
    <name>A0A1Q2CD11_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 7">30S ribosomal protein S9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsI</name>
        <name evidence="8" type="ORF">RPIT_03450</name>
        <name evidence="9" type="ORF">SAMN05428934_101290</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY31060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03450"/>
    <dbReference type="EnsemblBacteria" id="AQP43986">
        <property type="protein sequence ID" value="AQP43986"/>
        <property type="gene ID" value="RPIT_03450"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY31060">
        <property type="protein sequence ID" value="SDY31060"/>
        <property type="gene ID" value="SAMN05428934_101290"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03450"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00532_B">
        <property type="entry name" value="Ribosomal_S9_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023035">
        <property type="entry name" value="Ribosomal_S9_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_S9_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="PTHR21569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP43986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY31060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="176" mass="18895" checksum="61BDDFA27695436C" modified="2017-04-12" version="1">MTENVNEIEETGAEEITSFVDDENREIAYRSDANAAAAAGIEVRPAVVAPGAATGRRKEAVARVRIVPGSGQWTINGRTLEDYFPNKVHQQLVTDPFTVAGVEGSYDVIVRIHGGGITGQAGALRLGVARALNAVDTEASRPALKKAGMLTRDSRIIERKKAGLKKARKAPQYSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD26</accession>
    <name>A0A1Q2CD26_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome c oxidase polypeptide 4</fullName>
            <ecNumber evidence="10">7.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cytochrome aa3 subunit 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Cytochrome c oxidase polypeptide IV</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_03645</name>
        <name evidence="13" type="ORF">SAMN05428934_101330</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Part of cytochrome c oxidase, its function is unknown.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 = 4 Fe(III)-[cytochrome c] + 4 H(+)(out) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11436"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="7.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Associates with subunits I, II and III to form cytochrome c oxidase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the cytochrome c oxidase bacterial subunit CtaF family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.9" evidence="10"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY32255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03645"/>
    <dbReference type="EnsemblBacteria" id="AQP44018">
        <property type="protein sequence ID" value="AQP44018"/>
        <property type="gene ID" value="RPIT_03645"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY32255">
        <property type="protein sequence ID" value="SDY32255"/>
        <property type="gene ID" value="SAMN05428934_101330"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03645"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021050">
        <property type="entry name" value="Cyt_c_oxidase_su4_actinobac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12270">
        <property type="entry name" value="Cyt_c_ox_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017385">
        <property type="entry name" value="CtaF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR017385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP44018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY32255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="132" mass="14633" checksum="213B177E63D14F33" modified="2017-04-12" version="1">MKSERWIFGFLGIYFGVVAPVYWLMSGEIAGTLALAFSGLLGALIAGYLHIQARNFDPRPEDRKDGEVYEAAGELGFFAPKSIWPFWAAVVVAVIFLGPALQQAWITLLGLGMGIWATSGWVLEFYRGDYKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDA1</accession>
    <name>A0A1Q2CDA1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_04145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44103">
        <property type="protein sequence ID" value="AQP44103"/>
        <property type="gene ID" value="RPIT_04145"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04145"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="89" mass="8595" checksum="EDF827C81D2D3FC4" modified="2017-04-12" version="1">MQPRNTRSVLALVLSNVLGGVGVASGIAVGALLVASMSSEAFAGVGQALGVLGAGLLAVPLAALATRRGRRAALSLGYAIAVLGAAGQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDA7</accession>
    <name>A0A1Q2CDA7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_03975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03975"/>
    <dbReference type="EnsemblBacteria" id="AQP44077">
        <property type="protein sequence ID" value="AQP44077"/>
        <property type="gene ID" value="RPIT_03975"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03975"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="239" mass="25087" checksum="D8764F9A1A6D3232" modified="2017-04-12" version="1">MVRNGTRLTGRGVALVLLGALASAAAAYIGELDLLWLTVALVALPLLSVVYLVLARPRVRYERSVDPSQIPVGTTTRVVLRVANQSPAQSSALRFADAAPEPLGGGASFLIARGFGRWRQAVGYTVEATRRGRFHLGPLRGTATDPFALAARTFTAKGDESVLRVTPKVWPLGKLSGAAGMGSAGDATPSGWGRPVRTTSWSANTDTATTCAGSTGSCPPSRTTSWSGWRSIRGTRPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDB9</accession>
    <name>A0A1Q2CDB9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_04075</name>
        <name evidence="6" type="ORF">SAMN05428934_101418</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY34622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04075"/>
    <dbReference type="EnsemblBacteria" id="AQP44091">
        <property type="protein sequence ID" value="AQP44091"/>
        <property type="gene ID" value="RPIT_04075"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY34622">
        <property type="protein sequence ID" value="SDY34622"/>
        <property type="gene ID" value="SAMN05428934_101418"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04075"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="4">
        <location>
            <begin position="88"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY34622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="306" mass="32670" checksum="F67E2D677C5643F3" modified="2017-04-12" version="1">MSVFLIPEALAGERVDAAAARVTGHSRSRIESLIDGGNLLLAGAVITKGSQRVRGGELLELTEALTPSPVRLDPRLADGVLIVHEDADIVVVDKPVGVVAHPSLGFEGPSVVEHLAAAGVAVSTSGAPERQGIVQRLDVGTSGLMVVAKSEAAYSVLKQAFRDRTVDKTYHALVQGHPDPFEGTIEAPIARHPGADWKMAIVEGGRHSVTHYETIEAHRAATLLRIHLETGRTHQIRVHMAALGHPCVGDPLYGADPTLSARLGLDRQWLHAVELGFTHPGTGEYVSFRSQYPDDLDRALQIVRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDC8</accession>
    <name>A0A1Q2CDC8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycine cleavage system H protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gcvH</name>
        <name evidence="6" type="ORF">RPIT_04135</name>
        <name evidence="7" type="ORF">SAMN05428934_101431</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="3">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GcvH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY35025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04135"/>
    <dbReference type="EnsemblBacteria" id="AQP44101">
        <property type="protein sequence ID" value="AQP44101"/>
        <property type="gene ID" value="RPIT_04135"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY35025">
        <property type="protein sequence ID" value="SDY35025"/>
        <property type="gene ID" value="SAMN05428934_101431"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04135"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06848">
        <property type="entry name" value="GCS_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00272">
        <property type="entry name" value="GcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002930">
        <property type="entry name" value="GCV_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033753">
        <property type="entry name" value="GCV_H/Fam206"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017453">
        <property type="entry name" value="GCV_H_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715">
        <property type="entry name" value="PTHR11715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01597">
        <property type="entry name" value="GCV_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00527">
        <property type="entry name" value="gcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="5">
        <location>
            <begin position="17"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-lipoyllysine" evidence="3 4">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR617453-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY35025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="119" mass="12547" checksum="E5FBE0E2F0A40EED" modified="2017-04-12" version="1">MIRYTADHEWLDDSGDDVAVGITAHATEELGDIVFIELPEVGAELTTGDEAAVIESTKAASGIAAPFDGVVTAVNDELAESPEKVNEDPTGSWFFRIRPADPGALDSLLDEAAYQALIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDD8</accession>
    <name>A0A1Q2CDD8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Biotin transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_04190</name>
        <name evidence="7" type="ORF">SAMN05428934_101442</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY35401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04190"/>
    <dbReference type="EnsemblBacteria" id="AQP44111">
        <property type="protein sequence ID" value="AQP44111"/>
        <property type="gene ID" value="RPIT_04190"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY35401">
        <property type="protein sequence ID" value="SDY35401"/>
        <property type="gene ID" value="SAMN05428934_101442"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04190"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003339">
        <property type="entry name" value="ABC/ECF_trnsptr_transmembrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02361">
        <property type="entry name" value="CbiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP44111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY35401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="209" mass="22131" checksum="DF7E63472B7955A0" modified="2017-04-12" version="1">MNVHDSLLGLYEPGPGWLFRLRVGWKYLVVLALTLPPLIAGTPWVSLSAVLVTLALLWSSGITPPRAVRVGLPIWLMLAALVAYHLVSFDPSAAATHPVNILNAVLAARILTLTTSTPALMDALASGLRPLSWVRVDPQQVALAVALMIRSIPFLVGSVGDARDAARARGLDRNPALLLTPVVLGAVSYAQRTGEALHARGLPAGDEAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDG2</accession>
    <name>A0A1Q2CDG2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">30S ribosomal protein S2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsB</name>
        <name evidence="5" type="ORF">RPIT_04495</name>
        <name evidence="6" type="ORF">SAMN05428934_101505</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04495"/>
    <dbReference type="EnsemblBacteria" id="AQP44163">
        <property type="protein sequence ID" value="AQP44163"/>
        <property type="gene ID" value="RPIT_04495"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37027">
        <property type="protein sequence ID" value="SDY37027"/>
        <property type="gene ID" value="SAMN05428934_101505"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04495"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_S2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_S2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_S2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_S2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="PTHR12534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="SSF52313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01011">
        <property type="entry name" value="rpsB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="281"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="289"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY37027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="316" mass="34899" checksum="A89AB5173019848B" modified="2017-04-12" version="1">MAVVTTRQLLESGVHFGHQTRRWNPKMKRFIFTERNGIYIIDLQLSLSYIDKAYHFVKSTVARGGQVLFVGTKKQAQEAIAEQATRVGMPYVNQRWLGGMLTNFHTVTKRIQRLKELEGMDLTESSTSGLTKKELLQLEREKTKLDRTLGGIRDMARTPQAVWIVDTKKEHLAVDEARKLNIPIVGILDTNCDPDEVDYAVPGNDDAIRSVGLLTRIIADAVAEGLIERSSGRTGEEAVAEPMPDWERELLGADQAEQVEAAGDNPVVERDDANAIEAEATAEVDEAAAEDAVAERAEEVSETEAETVAADETPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDI3</accession>
    <name>A0A1Q2CDI3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">Translation initiation factor IF-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">infB</name>
        <name evidence="11" type="ORF">RPIT_04600</name>
        <name evidence="12" type="ORF">SAMN05428934_101526</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04600"/>
    <dbReference type="EnsemblBacteria" id="AQP44183">
        <property type="protein sequence ID" value="AQP44183"/>
        <property type="gene ID" value="RPIT_04600"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37522">
        <property type="protein sequence ID" value="SDY37522"/>
        <property type="gene ID" value="SAMN05428934_101526"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04600"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03702">
        <property type="entry name" value="IF2_mtIF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00100_B">
        <property type="entry name" value="IF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044145">
        <property type="entry name" value="IF2_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006847">
        <property type="entry name" value="IF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000178">
        <property type="entry name" value="TF_IF2_bacterial-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="PTHR43381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04760">
        <property type="entry name" value="IF2_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="SSF52156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00487">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01176">
        <property type="entry name" value="IF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="452"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="46"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="65"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="110"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="193"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="461"/>
            <end position="468"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="511"/>
            <end position="515"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="565"/>
            <end position="568"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY37522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="958" mass="99441" checksum="40D51E78481846D7" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDJ8</accession>
    <name>A0A1Q2CDJ8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome-binding factor A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rbfA</name>
        <name evidence="3" type="ORF">RPIT_04605</name>
        <name evidence="4" type="ORF">SAMN05428934_101527</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RbfA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY37547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04605"/>
    <dbReference type="EnsemblBacteria" id="AQP44184">
        <property type="protein sequence ID" value="AQP44184"/>
        <property type="gene ID" value="RPIT_04605"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY37547">
        <property type="protein sequence ID" value="SDY37547"/>
        <property type="gene ID" value="SAMN05428934_101527"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04605"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00003">
        <property type="entry name" value="RbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000238">
        <property type="entry name" value="RbfA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023799">
        <property type="entry name" value="RbfA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020053">
        <property type="entry name" value="Ribosome-bd_factorA_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33515">
        <property type="entry name" value="PTHR33515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02033">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89919">
        <property type="entry name" value="SSF89919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00082">
        <property type="entry name" value="rbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01319">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY37547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="146" mass="15738" checksum="231A5084131EF4C4" modified="2017-04-12" version="1">MANPRNAKLADQIQVILASTIERRVKDPRLGFVTITEVRLTGDNREATAFYTVLGDEEARAGTAAALESAKGMLRSTVGSQLGMKFTPSLSFVLDATPETARHIEDLLAQVQADDARAAAAAAGRTFAGDADPYRKPREESEDDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDT3</accession>
    <name>A0A1Q2CDT3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05245</name>
        <name evidence="3" type="ORF">SAMN05428934_101655</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY40862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44292">
        <property type="protein sequence ID" value="AQP44292"/>
        <property type="gene ID" value="RPIT_05245"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY40862">
        <property type="protein sequence ID" value="SDY40862"/>
        <property type="gene ID" value="SAMN05428934_101655"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05245"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY40862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="78" mass="8854" checksum="CD38F6B6FD57B9F3" modified="2017-04-12" version="1">MVDESTDQPLGEPLREVSDERMDDGYRRDEFGFRIDDQGHRVDEEGNRINADGEKIDIYGDGEGGDMPVPPIPPRLHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDV9</accession>
    <name>A0A1Q2CDV9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">DNA repair protein RecO</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">Recombination protein O</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">recO</name>
        <name evidence="10" type="ORF">RPIT_05055</name>
        <name evidence="11" type="ORF">SAMN05428934_101617</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Involved in DNA repair and RecF pathway recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the RecO family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY39835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05055"/>
    <dbReference type="EnsemblBacteria" id="AQP44260">
        <property type="protein sequence ID" value="AQP44260"/>
        <property type="gene ID" value="RPIT_05055"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY39835">
        <property type="protein sequence ID" value="SDY39835"/>
        <property type="gene ID" value="SAMN05428934_101617"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05055"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00201">
        <property type="entry name" value="RecO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022572">
        <property type="entry name" value="DNA_rep/recomb_RecO_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003717">
        <property type="entry name" value="RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042242">
        <property type="entry name" value="RecO_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33991">
        <property type="entry name" value="PTHR33991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02565">
        <property type="entry name" value="RecO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11967">
        <property type="entry name" value="RecO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="SSF57863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00613">
        <property type="entry name" value="reco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_rep/recomb_RecO_N" evidence="9">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY39835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="240" mass="25881" checksum="A917A0BE56917F6C" modified="2017-04-12" version="1">MPTYRDQAVVLRTHQLGEADRIITLLTRTHGKVRAVAKGVRRTSSKFGGRLEPFQHVDIQFAEGRGSLEVITQVESVHVSKLAADYSRFTAAEVLVETADRLVAEEWSPAVQQYRLLLGALRALETSGMPAPLIVDSYLLRALAIAGYAVATLNCAGCGDSDVRWFSPQGGGAVCTACRTSGSGALEAEASTHLGALVAGDWEAATAADLLTQQRVDGMVIAYATWHLDRALRSLPYFEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE35</accession>
    <name>A0A1Q2CE35_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Branched-chain-amino-acid transaminase</fullName>
            <ecNumber evidence="9">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">RPIT_05675</name>
        <name evidence="15" type="ORF">SAMN05428934_10382</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1T</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1</strain>
        </source>
    </reference>
    <reference evidence="14" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY67178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05675"/>
    <dbReference type="EnsemblBacteria" id="AQP44363">
        <property type="protein sequence ID" value="AQP44363"/>
        <property type="gene ID" value="RPIT_05675"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY67178">
        <property type="protein sequence ID" value="SDY67178"/>
        <property type="gene ID" value="SAMN05428934_10382"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05675"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00058"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00073"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00062"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052656">
        <property type="term" value="F:L-isoleucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052654">
        <property type="term" value="F:L-leucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052655">
        <property type="term" value="F:L-valine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825">
        <property type="entry name" value="PTHR11825"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01123">
        <property type="entry name" value="ilvE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="12" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 14" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="13">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00005072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00013053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR006468-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="AQP44363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="SDY67178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="360" mass="38920" checksum="7E2C36455F8ACE1A" modified="2017-04-12" version="1">MSSFVVQHNPHVLPAADRERLMADPGFGKVFSDHMAWAAWTPERGWHDRSIRPYGPLQLDPASAIFHYGQEVFEGLKAYRHADSSVWAFRPEMNAARMAASATRLALPPLSEGDFLDSIQALVETDRDWVPGGEEQSFYLRPFMIGVTPAMAVKPSRHVLYAVIGSPSSPYFEAGVRPVSIWLTRTYARAGAGGTGAAKCGGNYASSMAAQLEAESQGCDQVAFVDAGSPASVEELGGMNIMAVTRDGELHTPQLTGTILPGVTRASILDIAADHGLRVVERRIPVSSLLDDIDAGTVAELFACGTAAVITPISQLKDDSGVHRVGDGQAGPMTLELRQHLTDLQYGRRPDDRGWLRRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEE3</accession>
    <name>A0A1Q2CEE3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable transcriptional regulatory protein RPIT_06335</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_06335</name>
        <name evidence="6" type="ORF">SAMN05428934_103212</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the TACO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY70580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06335"/>
    <dbReference type="EnsemblBacteria" id="AQP44476">
        <property type="protein sequence ID" value="AQP44476"/>
        <property type="gene ID" value="RPIT_06335"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY70580">
        <property type="protein sequence ID" value="SDY70580"/>
        <property type="gene ID" value="SAMN05428934_103212"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06335"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00693">
        <property type="entry name" value="Transcrip_reg_TACO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017856">
        <property type="entry name" value="Integrase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002876">
        <property type="entry name" value="Transcrip_reg_TACO1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026564">
        <property type="entry name" value="Transcrip_reg_TACO1-like_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029072">
        <property type="entry name" value="YebC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12532">
        <property type="entry name" value="PTHR12532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01709">
        <property type="entry name" value="Transcrip_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75625">
        <property type="entry name" value="SSF75625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01033">
        <property type="entry name" value="TIGR01033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 4" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY70580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="257" mass="27362" checksum="7C82DBF59B579C0C" modified="2017-04-12" version="1">MSGHSKWATTKHKKAAIDAKRGKLFAKLIKNVEVAARLGGGDPAGNPTLYDAIQKAKKSSVPNDNIDRAVKRGSGAESGGHDYETIMYEAYGPAGVAILIECLTDNRNRSASDVRVAVTRNGGTMADVGSVQRLFARKGVVTVPKTQGDVEVHEDAVLEAALEAGLEEVSDAGDSWEAISDPNDVVDVRKAIEAAGLDYDSSEVQFVASFDQAVDEVDVAAKVFRIIDALEDSDDVQNVYTNVDLTPEVAEALDAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEI8</accession>
    <name>A0A1Q2CEI8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06705</name>
        <name evidence="3" type="ORF">SAMN05428934_110106</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ10135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44542">
        <property type="protein sequence ID" value="AQP44542"/>
        <property type="gene ID" value="RPIT_06705"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ10135">
        <property type="protein sequence ID" value="SDZ10135"/>
        <property type="gene ID" value="SAMN05428934_110106"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06705"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ10135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="147" mass="15062" checksum="F1220B64EEE6314C" modified="2017-04-12" version="1">MTPATRRATQMMVGGLVAGHVVGLTILGLALALGGPSAAVTAALGFAAVVIFYAIGQALEVVASELEVYQGLGLVMVSYAVRVVGIAAGLWFALSHPAVAPHVRDGWLVLSVAGTVIAWVTGVVLVASRQHVPVYDSEYRPPSADVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CES1</accession>
    <name>A0A1Q2CES1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TIGR02453 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07155</name>
        <name evidence="2" type="ORF">SAMN05428934_11013</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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            <strain evidence="1 3">RP1T</strain>
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            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP44619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44619">
        <property type="protein sequence ID" value="AQP44619"/>
        <property type="gene ID" value="RPIT_07155"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08241">
        <property type="protein sequence ID" value="SDZ08241"/>
        <property type="gene ID" value="SAMN05428934_11013"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR012808">
        <property type="entry name" value="CHP02453"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015996">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR36452">
        <property type="entry name" value="PTHR36452"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF2461"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ08241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="212" mass="23919" checksum="BF8229E5634E4F75" modified="2017-04-12" version="1">MSEVQGIPFEAIDFYEELEVNNSREWWASQRERYSSVVRAPMEALGAALEGEFGDTKVFRPNRDVRFSQDKSPYKTHQGVVASTASRMGWYVQISAEGLMTAAGWYASTAGQVARYRAALDDEDTGAELRRIVDELTAAGYAIDGDRLKTRPRGVEPDHPLLDLLRHRTLTASQQYGAPDWLPTPDVAERVRADWRAYRPLMAWLDRHVGDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEV9</accession>
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        <name evidence="3" type="ORF">SAMN05428934_11423</name>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
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    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
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    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="protein sequence ID" value="SDZ18201"/>
        <property type="gene ID" value="SAMN05428934_11423"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
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    </dbReference>
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        <location>
            <begin position="77"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ18201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="115" mass="12161" checksum="425B9289D54669D2" modified="2017-04-12" version="1">MTDKFTLIHAEKATHPVGLMTRLLHVSRAGYYSWVKRGDTPGPAATRRAEVTAAVIHSHTASNGVNGHRRVRADLSADGVPASEGMVRPRASAVGPSGRSVRARASPSGNQLTQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEX0</accession>
    <name>A0A1Q2CEX0_9ACTN</name>
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    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ18367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44651">
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        <property type="gene ID" value="RPIT_07370"/>
    </dbReference>
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        <property type="gene ID" value="SAMN05428934_11431"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
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            <begin position="37"/>
            <end position="181"/>
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        <location>
            <begin position="23"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ18367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="181" mass="18276" checksum="99DDE0DEDAD2F268" modified="2017-04-12" version="1">MNRRIVSPVLAVLAALAMTACSGTPTDTTPASPADAATTAAPVETTADAVPSSEPAPAPATSTDAAVGGEQSVAQACMSMAGPIAEASEKMSEIASVATTDPQSAVDTWSALVEAYESVAGTVTNAEVKAAASAVRDDLASLRDAMQKVYVELDMSAMSEFTDATAEWQDSQTNLQTICAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEX5</accession>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="83" mass="8790" checksum="768D5CBBC5DD254D" modified="2017-04-12" version="1">MDSDAIFQGQVRESAGLEVMAKLMLYDTFGPALGFGLKAGVDLDAKMEADGLMARVKIYLSGSVLVQVSLKIPVINVDVAETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF07</accession>
    <name>A0A1Q2CF07_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cation transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Cobalt-zinc-cadmium efflux system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_07665</name>
        <name evidence="8" type="ORF">SAMN05428934_12114</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="AQP44699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000021">
        <property type="protein sequence ID" value="SDZ22840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07665"/>
    <dbReference type="EnsemblBacteria" id="AQP44699">
        <property type="protein sequence ID" value="AQP44699"/>
        <property type="gene ID" value="RPIT_07665"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ22840">
        <property type="protein sequence ID" value="SDZ22840"/>
        <property type="gene ID" value="SAMN05428934_12114"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07665"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="SSF160240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ22840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="305" mass="32396" checksum="323D4C8C22B4A9CE" modified="2017-04-12" version="1">MSGNHGHDHTAGLADHRGRLAVVLGITVTVLIVEVVGAVISGSLALLADAGHMLTDVAGLSMALVAATLSRRPATPFRTWGFLRAEILGAAAQALLLLAVGVFILIEAIQRLRQPPEVTSTAMVVFGLIGLLGNVVGMFILARARAANLNMRAAFLEVVNDALGSVAVLVAAVVIATTGFDRADAIASLVIVVLIVPRTIRLLRDAVHVLMESTPPGLDLAAVRKSILQLSHVHDVHDLHATQVATGIPVLTAHVVIDDECFRDKHALHLLDAVQERLRHDFDIEHSTIQLEGPNHAAHEHPVHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF30</accession>
    <name>A0A1Q2CF30_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44724">
        <property type="protein sequence ID" value="AQP44724"/>
        <property type="gene ID" value="RPIT_07820"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07820"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="177" mass="18279" checksum="5FAA6C4AD5442DC9" modified="2017-04-12" version="1">MGRSVRASLRRRARTVAVAGTVAVFAYAVFAAFQILVLNPLAAAPGADLAQIYADVEAAGESMGVPSVVTILTVGPIVASALLARTWARPEPEPRMVLVLYLALLALGELGHTVASFGPGMALADTYLISGGDHSPWAVPLQAVSGIAFMVAVILAPGAWAAAGDRRAGVPLRWHNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF43</accession>
    <name>A0A1Q2CF43_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_07930</name>
        <name evidence="3" type="ORF">SAMN05428934_11326</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07930"/>
    <dbReference type="EnsemblBacteria" id="AQP44742">
        <property type="protein sequence ID" value="AQP44742"/>
        <property type="gene ID" value="RPIT_07930"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16483">
        <property type="protein sequence ID" value="SDZ16483"/>
        <property type="gene ID" value="SAMN05428934_11326"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07930"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ16483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="308" mass="32517" checksum="BAA2194F520C5BA6" modified="2017-04-12" version="1">MSQEPQLIATGAPSDPPSGLTYPLALRLRGSSPFQAVFGILVAFSAFALLVPLFSELVLRVAHLVRGGGDYAAYRQQAGAYELAEGPAAGHLALALLIPVSILIVRYIHGVRPRWLFSVQPGLRWRYLAIMLVVAALALNGVLWLSFLAKGAPVFHGGQDGWLTFLLVVAVTSPLQTAAEEVFFRGYLLQAIGSASGRTWVGVVGSAVLFALLHGVQNPALFAHRLAFGLIAGALVVVTGGLEAGIAAHVVNNIAAYAYAMFTTSVAELRAITALSWADAGWDILGFLTVALLAILLARRLRMAAATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF57</accession>
    <name>A0A1Q2CF57_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sec-independent protein translocase protein TatC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tatC</name>
        <name evidence="7" type="ORF">RPIT_08000</name>
        <name evidence="8" type="ORF">SAMN05428934_11340</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TatC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08000"/>
    <dbReference type="EnsemblBacteria" id="AQP44754">
        <property type="protein sequence ID" value="AQP44754"/>
        <property type="gene ID" value="RPIT_08000"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16766">
        <property type="protein sequence ID" value="SDZ16766"/>
        <property type="gene ID" value="SAMN05428934_11340"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08000"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002033">
        <property type="entry name" value="TatC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30371">
        <property type="entry name" value="PTHR30371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01840">
        <property type="entry name" value="TATCFAMILY"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00945">
        <property type="entry name" value="tatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="226"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP44754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDZ16766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="290" mass="31927" checksum="85851892BE14D948" modified="2017-04-12" version="1">MTTASTEPTTKRRRLEWLRPPQGGPGGTMSLYDHLRELRYRVTIAAGAIFLSAIFSILFYRQLVSIIMAPWMRARTALEAARPDANLMVVNNGVTSSFTFAVVLCLVAGVMLSVPVWLYQLWAFVAPGLVAKEKKYALAFIGAATPLFLAGCALGYYVWPKGIEVLLSFTPQDMGITNMQDMAEFLSMEIKIILVFGLSFILPVIVVALNMAGVVRGYMLKRWRKGVIFGSVVLAAVATPTTDPFSMLALAVPVSGMFLIAEVICRVWDKKRGIDEQFVAEFAIDLDDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF85</accession>
    <name>A0A1Q2CF85_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Argininosuccinate lyase</fullName>
            <shortName evidence="5">ASAL</shortName>
            <ecNumber evidence="3 5">4.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Arginosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">argH</name>
        <name evidence="8" type="ORF">RPIT_08195</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>2-(N(omega)-L-arginino)succinate = fumarate + L-arginine</text>
            <dbReference type="Rhea" id="RHEA:24020"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="EC" id="4.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.1" evidence="3 5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08195"/>
    <dbReference type="EnsemblBacteria" id="AQP44779">
        <property type="protein sequence ID" value="AQP44779"/>
        <property type="gene ID" value="RPIT_08195"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08195"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00114"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004056">
        <property type="term" value="F:argininosuccinate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01359">
        <property type="entry name" value="Argininosuccinate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00006">
        <property type="entry name" value="Arg_succ_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029419">
        <property type="entry name" value="Arg_succ_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009049">
        <property type="entry name" value="Argininosuccinate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814">
        <property type="entry name" value="PTHR43814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14698">
        <property type="entry name" value="ASL_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00838">
        <property type="entry name" value="argH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="6">
        <location>
            <begin position="11"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="ASL_C2" evidence="7">
        <location>
            <begin position="369"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="474" mass="50841" checksum="D7DD86FF30F88BB8" modified="2017-04-12" version="1">MVNDSGRLWGGRFEGGPSEAMFALSKSTQFDWRLALHDIRGSRAHAKALLQAGLLTAEQATAMDDGLAELARRVQEGEFLPAESDEDVHGALERGLKEIVGPVLGGRIRAGRSRNDQIATLIRSYLREEIRNVASDLVGVIDALASQAERHPGAVMPGRTHLQSAQPILLGHHLLAHAWPLVRDIERLRDLDKRLAVSPYGSAALAGTSLGLDPELVAAELGFESSVPNSIDGTAARDLIAEAAFVLAQIGVDLSRLSEDVIIWCTAEFGFATLDDAWSTGSSIMPQKKNPDVAELARGKAGRLIGNLAGLLATLKGLPLAYNRDLQEDKEPIFDGIDQLRVLVPAVAGMVGTLTFHEERMAEVAPRGFSLATDVADYLVRSNVPFSVAHEVAGETVRYCEARGITLQELTVDDVTSISDHLDEGVLEVLTVEGSVASRDGRGGTAPVRVAEQIQELRAARGDLASWAQNSLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF87</accession>
    <name>A0A1Q2CF87_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Proteasome accessory factor B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08015</name>
        <name evidence="3" type="ORF">SAMN05428934_11344</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08015"/>
    <dbReference type="EnsemblBacteria" id="AQP44757">
        <property type="protein sequence ID" value="AQP44757"/>
        <property type="gene ID" value="RPIT_08015"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16851">
        <property type="protein sequence ID" value="SDZ16851"/>
        <property type="gene ID" value="SAMN05428934_11344"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08015"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0647">Proteasome</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WYL" evidence="1">
        <location>
            <begin position="148"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ16851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="311" mass="34665" checksum="32CA11C4AEF33921" modified="2017-04-12" version="1">MSARKSERLVNLLIALLSTRRYLTRQELRELVEGYRMAPSDAAFERQFERDKEELRASGIVIETGSNDPDSDEDDGYRVNRSEFELPPIEFTTAELGALGLAGQAWQSSVAAEHTAQAFEALRAAGASPDPALIPSVRPQVEVREPDFDVVYEAVLNRTQIQFGYAGQRRRLQPWTMVQRRGRWYVIGFDVDRGEDRRFKLARFTAPAETIGRAGAYSIPPEAKSLTVTRDEPTHAVVTVALHDDVAAEWRQATPVAWPHSLPDQFRAYEVPALSLEAAIDEVAGAGPDAILLAPSEARDVLIERLRRAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF90</accession>
    <name>A0A1Q2CF90_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">S9 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_07765</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44715">
        <property type="protein sequence ID" value="AQP44715"/>
        <property type="gene ID" value="RPIT_07765"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07765"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9" evidence="3">
        <location>
            <begin position="480"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="186"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="706" mass="75226" checksum="8DF594B5B1620DC8" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFA5</accession>
    <name>A0A1Q2CFA5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SseB protein N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_08285</name>
        <name evidence="4" type="ORF">SAMN05428934_11518</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08285"/>
    <dbReference type="EnsemblBacteria" id="AQP44796">
        <property type="protein sequence ID" value="AQP44796"/>
        <property type="gene ID" value="RPIT_08285"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19366">
        <property type="protein sequence ID" value="SDZ19366"/>
        <property type="gene ID" value="SAMN05428934_11518"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08285"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009839">
        <property type="entry name" value="SseB_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07179">
        <property type="entry name" value="SseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SseB" evidence="2">
        <location>
            <begin position="28"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ19366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="164" mass="17435" checksum="CBCA1CC9EFE0A4EB" modified="2017-04-12" version="1">MTELRSLAQPSARFAGDDGAPDPLTRAAIARADDRTGYTRAIVALCSSRLLLPIVASGDDTDHPDPDRHAEMAAVTLADEGSDYLLAFTGYDSLRAWQPDARPVPCHLDELCATVEPAGASKLLLDVAGPVPFVIEGDLLAMLAQGHSLVEFDDGEFAWVTTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFA8</accession>
    <name>A0A1Q2CFA8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_08240</name>
        <name evidence="3" type="ORF">SAMN05428934_11527</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000015">
        <property type="protein sequence ID" value="SDZ19552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08240"/>
    <dbReference type="EnsemblBacteria" id="AQP44788">
        <property type="protein sequence ID" value="AQP44788"/>
        <property type="gene ID" value="RPIT_08240"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ19552">
        <property type="protein sequence ID" value="SDZ19552"/>
        <property type="gene ID" value="SAMN05428934_11527"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08240"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ19552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="355" mass="39165" checksum="93D9C552ABF29310" modified="2017-04-12" version="1">MTAHRIDGQLRVTGHAEVLKVVEDPATYSSKVSRFLQVPNNLDGADHERFREILDPYFSEHRMAELEPQVRSVARRLVGELPRGESIDAVRGLGISFSVDAMLAWLGWSQDFEGELIDWVIDNARATRSGELDRTREVAERFDAIIRRVAAPRLDRLDEAPRDVTDELLRETVDGRALTHEEIVSILRNWTGGDLTSLALCVGVVVHQIATDPAIEADVRDRVGDPARLDAAIDELLRIDDPFVSNRRRATRDATVGGCPVRAGEKLTVEWTDANRDPAVFGDPDRYAPERNAAANLVYGAGPHVCPGRPLATLELRVLLEELLAGTTDLAPSEEPGVRAERPLGGWLSAPFVAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFD7</accession>
    <name>A0A1Q2CFD7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsP</name>
        <name evidence="5" type="ORF">RPIT_08600</name>
        <name evidence="6" type="ORF">SAMN05428934_10731</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial ribosomal protein bS16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY96850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08600"/>
    <dbReference type="EnsemblBacteria" id="AQP44842">
        <property type="protein sequence ID" value="AQP44842"/>
        <property type="gene ID" value="RPIT_08600"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY96850">
        <property type="protein sequence ID" value="SDY96850"/>
        <property type="gene ID" value="SAMN05428934_10731"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08600"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00385">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000307">
        <property type="entry name" value="Ribosomal_S16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020592">
        <property type="entry name" value="Ribosomal_S16_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023803">
        <property type="entry name" value="Ribosomal_S16_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919">
        <property type="entry name" value="PTHR12919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00886">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54565">
        <property type="entry name" value="SSF54565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00002">
        <property type="entry name" value="S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00732">
        <property type="entry name" value="RIBOSOMAL_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="81"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY96850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="161" mass="17440" checksum="E4A7A935E8B24D55" modified="2017-04-12" version="1">MATKIRLKRLGKIRSPHYRIIVIDSRSKREGKAIEEIGLYHPKNDPSFIRVDSERAQYWLSVGAQPTEAVVAIFKRTGDWQKFTGDTTPSGVDPQPEPRDREAEFAKALAEDGGTTAPAISKAKKKADEAAAKAKDEAPAADEAAPADDAQAEAEAPAEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFE6</accession>
    <name>A0A1Q2CFE6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_08525</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44831">
        <property type="protein sequence ID" value="AQP44831"/>
        <property type="gene ID" value="RPIT_08525"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08525"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="71"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="474"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="484"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="641" mass="67736" checksum="F31DB612EC5C3E76" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFG0</accession>
    <name>A0A1Q2CFG0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_08495</name>
        <name evidence="2" type="ORF">SAMN05428934_10710</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY96349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08495"/>
    <dbReference type="EnsemblBacteria" id="AQP44827">
        <property type="protein sequence ID" value="AQP44827"/>
        <property type="gene ID" value="RPIT_08495"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY96349">
        <property type="protein sequence ID" value="SDY96349"/>
        <property type="gene ID" value="SAMN05428934_10710"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08495"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY96349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="220" mass="23428" checksum="DADA2AC7F481CD37" modified="2017-04-12" version="1">MKPEAIVFDMDGTLTDTEAVWDVVRRGLAAEHDLPWPDGTTQAMMGMSTGEWSRHLVEAVGLPYSPDEAARRTIDGMADHYREGITVLPGAVEAVRRMAEHYPIAIASSSPRQLIDAAVEVLGLGELLSATVSTEEVAAGKPAPDGYLKAAELLGVDPTRCIAVEDATNGILSALNAGMTVVAVPPHFHPPAEDLLARTTVLDNLDELTVDLVESLLPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFH7</accession>
    <name>A0A1Q2CFH7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmB</name>
        <name evidence="5" type="ORF">RPIT_08725</name>
        <name evidence="6" type="ORF">SAMN05428934_10755</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08725"/>
    <dbReference type="EnsemblBacteria" id="AQP44863">
        <property type="protein sequence ID" value="AQP44863"/>
        <property type="gene ID" value="RPIT_08725"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97398">
        <property type="protein sequence ID" value="SDY97398"/>
        <property type="gene ID" value="SAMN05428934_10755"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08725"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00373">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribo_L28/L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribo_L28/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001383">
        <property type="entry name" value="Ribosomal_L28"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00009">
        <property type="entry name" value="L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY97398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="61" mass="6708" checksum="C1C8D6EC34F54FA0" modified="2017-04-12" version="1">MAAKCDVCAKGPGFGHNVPWSKKKTNRRWNPNIQRVRATINGAPQRVNVCTSCLKAGKVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFI0</accession>
    <name>A0A1Q2CFI0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_08640</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08640"/>
    <dbReference type="EnsemblBacteria" id="AQP44847">
        <property type="protein sequence ID" value="AQP44847"/>
        <property type="gene ID" value="RPIT_08640"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08640"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="147"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="225" mass="24519" checksum="10F4D9245BB7EF3D" modified="2017-04-12" version="1">MTRRILVADDDPMVREAYRMFFSRHDTLEVVGEARDGNEAVSLHRELKPDITLMDLQMPDKSGVEAIGEICQADPTACIVALTTFGTRDYIVAALRAGAAGYLLKDAGGPALLAAVEQALDGEMPLSSAVRRELVRDVVDSAVRERPALPDPGLAPRERELLTWLAQGLTNQQIGQKMFVSEGSVKQYLSHIGDKLGLKSRTQILMRAVQLGIVDPTELDPITGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFL5</accession>
    <name>A0A1Q2CFL5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA thioester hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_08985</name>
        <name evidence="2" type="ORF">SAMN05428934_107110</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08985"/>
    <dbReference type="EnsemblBacteria" id="AQP44909">
        <property type="protein sequence ID" value="AQP44909"/>
        <property type="gene ID" value="RPIT_08985"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98441">
        <property type="protein sequence ID" value="SDY98441"/>
        <property type="gene ID" value="SAMN05428934_107110"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08985"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY98441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="288" mass="31988" checksum="827AD9503EB968BC" modified="2017-04-12" version="1">MFDVTLPLRWSDLDAQGHVNNAIIVDYLQEARVAFLRSGPASQLLDEGVVVVSHQVEYRRPIDYSDDGVHVALGVSALGGSRLELAYELRQDGELAVRARTTLCAFDFEAQRPIRLKPEYRTFLGGFVTEAEPLRPLAAPHLEGRGTAIDLPVRWTDLDSYGHVNNAKVYDYLQQARITATTTWDPSMARAGSEGSEYLWLVARQDVDYLAQLEHRMEPYAVRVAPAHLGASSITLVAELVDPADERVFVRARTILVCADRRGFKIELPGAIRDALSAHLIDPDQPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFL6</accession>
    <name>A0A1Q2CFL6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP dependent helicase, Lhr family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">DEAD/DEAH box helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_08960</name>
        <name evidence="5" type="ORF">SAMN05428934_107105</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08960"/>
    <dbReference type="EnsemblBacteria" id="AQP44904">
        <property type="protein sequence ID" value="AQP44904"/>
        <property type="gene ID" value="RPIT_08960"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98351">
        <property type="protein sequence ID" value="SDY98351"/>
        <property type="gene ID" value="SAMN05428934_107105"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08960"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013701">
        <property type="entry name" value="DEAD/DEAH_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08494">
        <property type="entry name" value="DEAD_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="31"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="270"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1232"/>
            <end position="1264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP44904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY98351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="1496" mass="158917" checksum="262F279DBF55B2EE" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFP0</accession>
    <name>A0A1Q2CFP0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">AI-2E family transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Predicted PurR-regulated permease PerM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_08815</name>
        <name evidence="9" type="ORF">SAMN05428934_10773</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08815"/>
    <dbReference type="EnsemblBacteria" id="AQP44880">
        <property type="protein sequence ID" value="AQP44880"/>
        <property type="gene ID" value="RPIT_08815"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97788">
        <property type="protein sequence ID" value="SDY97788"/>
        <property type="gene ID" value="SAMN05428934_10773"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08815"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="321"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP44880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY97788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="382" mass="40348" checksum="3CCFC0345CDCB56B" modified="2017-04-12" version="1">MSPEARTPVEDTDPPQDVGPGDTARPGLPMLVAVAISLAAIGLSLALLQSISGIIAPIFLAVNLMVVAYPLFVWLVASRVPRGIAAVITGVAVFTVILLGAAMLVWSITAMIGALSEYSERFVELFDRGVSLLGSFGIDNVSFTESLDSISPESLLGLAGGLISNASGAAGIILIILVAMVFMIVDLTMLTKRTTLTHRLHPEFTDAISSFVAGIRRYWVVTTVFGLVVAVLDGIVLVALGVSLPLVWAVLSFVTNYIPNVGFFLGLVPPALLAYFEQGPVTATFVIAAYGVINVVFQAFIQPKVAGDAVGVTGTISFISLLLWAWVFGPLGALIALPSTLAVKALLIDPDPRLRWVNAFISNDPIGDVDVHPEETRSEHSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFU2</accession>
    <name>A0A1Q2CFU2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sulfate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09125</name>
        <name evidence="4" type="ORF">SAMN05428934_107138</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY98991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44930">
        <property type="protein sequence ID" value="AQP44930"/>
        <property type="gene ID" value="RPIT_09125"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY98991">
        <property type="protein sequence ID" value="SDY98991"/>
        <property type="gene ID" value="SAMN05428934_107138"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09125"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY98991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="124" mass="14248" checksum="984EA3C156467891" modified="2017-04-12" version="1">MIRLLWTASAEVRYFLRRYMPSNIVLDLIRTRKGLKWGIPAMLLAGPYLAIAFWCTTLIESGGPGWLHLVVLLCIWNALKMLAIGPVSLSLLVRTRVRERHARMHINQETRDEPQLPELTRSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFU6</accession>
    <name>A0A1Q2CFU6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA 2',3'-cyclic phosphodiesterase</fullName>
            <shortName evidence="1">RNA 2',3'-CPDase</shortName>
            <ecNumber evidence="1">3.1.4.58</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_09470</name>
        <name evidence="3" type="ORF">SAMN05428934_102412</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + H2O = a 3'-end 2'-phospho-ribonucleotide-RNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11828"/>
            <dbReference type="Rhea" id="RHEA-COMP:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:17353"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:83064"/>
            <dbReference type="ChEBI" id="CHEBI:173113"/>
            <dbReference type="EC" id="3.1.4.58"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 2H phosphoesterase superfamily. ThpR family.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.58" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY60065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09470"/>
    <dbReference type="EnsemblBacteria" id="AQP44984">
        <property type="protein sequence ID" value="AQP44984"/>
        <property type="gene ID" value="RPIT_09470"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY60065">
        <property type="protein sequence ID" value="SDY60065"/>
        <property type="gene ID" value="SAMN05428934_102412"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09470"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004113">
        <property type="term" value="F:2',3'-cyclic-nucleotide 3'-phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008664">
        <property type="term" value="F:2'-5'-RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01940">
        <property type="entry name" value="RNA_CPDase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004175">
        <property type="entry name" value="RNA_CPDase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35561">
        <property type="entry name" value="PTHR35561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="SSF55144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02258">
        <property type="entry name" value="2_5_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="short sequence motif" description="HXTX 1" evidence="1">
        <location>
            <begin position="42"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXTX 2" evidence="1">
        <location>
            <begin position="129"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="42"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY60065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="182" mass="19944" checksum="C08539B48FAC8E17" modified="2017-04-12" version="1">MGKRMFTAVLPPEDVVQQIDTLVEPRREAAPDLRWRRPDGWHLTTSFMGSVPDSHLERLVEELGAAAARTPRFVVRLSGGIAFPHAGKAKILALAAHGAEGGLDALARRCRSAANNAGVAVDGATFVGHLTLARHNRGIEATRWLGILDSFPGWSWTADELVLIESHQVGRHYEVVERFALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFZ5</accession>
    <name>A0A1Q2CFZ5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 11">Cytidine deaminase</fullName>
            <ecNumber evidence="6 11">3.5.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Cytidine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">RPIT_09765</name>
        <name evidence="14" type="ORF">SAMN05428934_102352</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1T</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 11">This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 11">
            <text>2'-deoxycytidine + H(+) + H2O = 2'-deoxyuridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13433"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15698"/>
            <dbReference type="ChEBI" id="CHEBI:16450"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>cytidine + H(+) + H2O = NH4(+) + uridine</text>
            <dbReference type="Rhea" id="RHEA:16069"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5 11">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.5" evidence="6 11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY58447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09765"/>
    <dbReference type="EnsemblBacteria" id="AQP45036">
        <property type="protein sequence ID" value="AQP45036"/>
        <property type="gene ID" value="RPIT_09765"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY58447">
        <property type="protein sequence ID" value="SDY58447"/>
        <property type="gene ID" value="SAMN05428934_102352"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09765"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004126">
        <property type="term" value="F:cytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006262">
        <property type="entry name" value="Cyt_deam_tetra"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01354">
        <property type="entry name" value="cyt_deam_tetra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="12">
        <location>
            <begin position="3"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AQP45036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY58447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="131" mass="13559" checksum="E591894B80A66849" modified="2017-04-12" version="1">MNVDWDSLRAAANDMAARAYAPYSGYPVGAAALVDDGRVVAGCNVENAAYGVTLCAECGLISSLVAGGGGRLVAFTCVNGEGTVITPCGRCRQLLFEHGGRELVLETPAGFRTLDEMLPQGFGPADLNAFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
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            <authorList>
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                <person name="Schumann P."/>
                <person name="Lal R."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="AQP45034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY58524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="150" mass="16052" checksum="4B5CFFA421C434D8" modified="2017-04-12" version="1">MLDRLFNAAALWTALGLLSGFYWREITKFSGFEDRSETMLATAHTHALSLGTLVLLAVLALAKTFGIAEKSGRLFVTLWHVGLGLTFGAMVVKGTLQVLGVPLAESAMWAGIGGLGHMVITGTLVYFFVILRRALKTTDATATLPATVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG07</accession>
    <name>A0A1Q2CG07_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative hemolysin</fullName>
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    </protein>
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        <name evidence="13" type="ORF">SAMN05428934_102346</name>
    </gene>
    <organism evidence="12 14">
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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            <authorList>
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                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
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            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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        </source>
    </reference>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP45043">
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        <property type="gene ID" value="RPIT_09800"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY58256"/>
        <property type="gene ID" value="SAMN05428934_102346"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
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        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
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        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
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            <end position="76"/>
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            <end position="120"/>
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            <end position="154"/>
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            <end position="277"/>
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        </location>
    </feature>
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        </source>
    </evidence>
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    </evidence>
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            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY58256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="439" mass="47588" checksum="7C79C7C705B2AD2A" modified="2017-04-12" version="1">MWSDVALIALFILIGGLFAAAEMALVTLRDSQIKQLSTKGKRGRAIERLTSNPNLFLSSVQIGVTLSGFLSAAFGGATLAEAMAPALMRWGVPESVAFTGSLVFVTVVISYFSIVVGELTAKRLAMQRAESFSLALAPMVSGIAKLARPLIWFLDLSTNALVRLLGGDPGQARDEVSDEELRAMVVGSSTLGQEERRIVDEVFDAGERTLREVMVPRTEVDFLPGDMPIVRAYREVRGAPHSRYPVTDGSPDRIVGFVHVRDLMDVEGSAREGNVASLARQVLSLPETVRILRAMTSMRGARSHLAIVRDEYGGTAGIVTLEDLMEELIGDITDEYDEAVERREIDEVDGLTTIEEFAELTGFVIPEGPYDTVAGFFMAETGRLPEVGSEATVSLEARAEDDDEPGVFTLTVTALDGRRASWFALKRLSDPDPAEEGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG54</accession>
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        <submittedName>
            <fullName evidence="4">Uncharacterized membrane protein</fullName>
        </submittedName>
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        <name evidence="4" type="ORF">SAMN05428934_102280</name>
    </gene>
    <organism evidence="3 5">
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
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    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY56412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10125"/>
    <dbReference type="EnsemblBacteria" id="AQP45102">
        <property type="protein sequence ID" value="AQP45102"/>
        <property type="gene ID" value="RPIT_10125"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56412">
        <property type="protein sequence ID" value="SDY56412"/>
        <property type="gene ID" value="SAMN05428934_102280"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
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        <location>
            <begin position="114"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY56412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="168" mass="19174" checksum="0CFF44A352954603" modified="2017-04-12" version="1">MARYERETLSEPGRRRPLLPKVQLDSEAFGAFAEAAARFMGTGKFIVYMTVFVVVWITLNVVGLLGLKWDPYPFILLNLFFSTQASYAAPLILLAQNRQEVRDKMSLDDDRRIAAQARADMDFLAREIAAIRMNLGELATRDFVRGELRTELRELAERLERTGEDVTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG78</accession>
    <name>A0A1Q2CG78_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase sigma factor SigE</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">RNA polymerase sigma-70 factor, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_10150</name>
        <name evidence="8" type="ORF">SAMN05428934_102275</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10150"/>
    <dbReference type="EnsemblBacteria" id="AQP45107">
        <property type="protein sequence ID" value="AQP45107"/>
        <property type="gene ID" value="RPIT_10150"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56275">
        <property type="protein sequence ID" value="SDY56275"/>
        <property type="gene ID" value="SAMN05428934_102275"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10150"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="23"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="122"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY56275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="192" mass="21560" checksum="0EDDB318DADB0BBD" modified="2017-04-12" version="1">MFRGRGAKKVTDSSWTAPTWQELVRDHSTQVYRLAYRLTGNQHDAEDLTQDVFVRVFKSIHTFQPGTLEGWLHRITTNLFLDQARRRQRIRMDALSTAPDHVWGSSTGPAELHNDAELDADVAAALKALNPEQRVAVVLCDIEGLSYEEIAEVLDVKLGTVRSRIARGRAALRDSLAHRAPTEGRSRYLGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGB5</accession>
    <name>A0A1Q2CGB5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Plasmid maintenance system killer</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Proteic killer suppression protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10425</name>
        <name evidence="2" type="ORF">SAMN05428934_102220</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY54782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10425"/>
    <dbReference type="EnsemblBacteria" id="AQP45158">
        <property type="protein sequence ID" value="AQP45158"/>
        <property type="gene ID" value="RPIT_10425"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY54782">
        <property type="protein sequence ID" value="SDY54782"/>
        <property type="gene ID" value="SAMN05428934_102220"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10425"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007711">
        <property type="entry name" value="HigB-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40266">
        <property type="entry name" value="PTHR40266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05015">
        <property type="entry name" value="HigB-like_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY54782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="93" mass="10918" checksum="42584CB289D8C029" modified="2017-04-12" version="1">MIRSFGDKETERLWRRERMRSIGPRIHRVALRKLRQVGSAESIEDLRVPPGNRLEALKGDRAGQHSIRINDQWRICFVWTAAGPEEVQIVDYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGC5</accession>
    <name>A0A1Q2CGC5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucose-1-phosphate adenylyltransferase</fullName>
            <ecNumber evidence="9">2.7.7.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ADP-glucose pyrophosphorylase</fullName>
            <shortName evidence="9">ADPGlc PPase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">ADP-glucose synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">glgC</name>
        <name evidence="12" type="ORF">RPIT_10165</name>
        <name evidence="13" type="ORF">SAMN05428934_102272</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>alpha-D-glucose 1-phosphate + ATP + H(+) = ADP-alpha-D-glucose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:12120"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.7.7.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9 10">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.27" evidence="9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10165"/>
    <dbReference type="EnsemblBacteria" id="AQP45110">
        <property type="protein sequence ID" value="AQP45110"/>
        <property type="gene ID" value="RPIT_10165"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56180">
        <property type="protein sequence ID" value="SDY56180"/>
        <property type="gene ID" value="SAMN05428934_102272"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10165"/>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008878">
        <property type="term" value="F:glucose-1-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00624">
        <property type="entry name" value="GlgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011831">
        <property type="entry name" value="ADP-Glc_PPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005836">
        <property type="entry name" value="ADP_Glu_pyroP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023049">
        <property type="entry name" value="GlgC_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43523">
        <property type="entry name" value="PTHR43523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02091">
        <property type="entry name" value="glgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00808">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00809">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00810">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 9 10" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0321">Glycogen metabolism</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 9 12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="11">
        <location>
            <begin position="9"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha-D-glucose 1-phosphate binding" evidence="9">
        <location>
            <begin position="179"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>alpha-D-glucose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>alpha-D-glucose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>alpha-D-glucose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
        </ligand>
    </feature>
    <feature type="site" description="Could play a key role in the communication between the regulatory and the substrate sites" evidence="9">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="site" description="Could play a key role in the communication between the regulatory and the substrate sites" evidence="9">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP45110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY56180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="408" mass="44895" checksum="4D59EF691EC0F728" modified="2017-04-12" version="1">MVARPKVLSIVLAGGEGKRLMPLTADRAKPAVPFGGTYRLIDFVLSNLANSNLRQIAVLTQYKSHSLDRHIAKTWRFSTMLGNYVAPVPAQQRLGPRWYQGSADAIHQSLNLIRDANPDYVVVFGADNIYRMDVEQMIDAHVDSGLGATVAGIRVPRRDATEFGIIDAAPDRKIKSFLEKPSDPPGLPDSPDESFASMGNYVFSRHALVDALRADAENPTARHDMGGDIIPWFTGQGEAQVYDFRDNQVPGATEKDVNYWRDVGTIDAFHEAHMDLVSIEPEFNLYNSEWPIWTDQVQLPGAKFVIRGRAEDSIVSAGCIISGGEVDRTVLSPNVHVDKWAQVSDSVLMDSVRIGRDAVVRRAILDKHVVVPDGVQIGVDHEHDRARGFAVSDTGIVVVGKDVVVPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGF6</accession>
    <name>A0A1Q2CGF6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-methyladenine DNA glycosylase AlkD</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">DNA alkylation repair protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10680</name>
        <name evidence="2" type="ORF">SAMN05428934_102169</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY53203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45202">
        <property type="protein sequence ID" value="AQP45202"/>
        <property type="gene ID" value="RPIT_10680"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY53203">
        <property type="protein sequence ID" value="SDY53203"/>
        <property type="gene ID" value="SAMN05428934_102169"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10680"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014825">
        <property type="entry name" value="DNA_alkylation"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08713">
        <property type="entry name" value="DNA_alkylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY53203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="220" mass="24837" checksum="16641B4109439409" modified="2017-04-12" version="1">MSTTDDILAELASLEDPKMRAVNERHGDDHGVNLTKMRAIAKRLKTDPELAVELWATDDTAARLLAILISRPRQYSADDLDSMLREARAPKVHGWLVNYIVKKSPHAEELRQRWFTDADPVVASAGWALTTERVVKKPGGLDLVALLDQIEAEMKGAPDRLQWAMNETLANIGIHHPEHRERALAIGERLEVLKDYPTPPNCTSPFAPIWINEMVRRRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGI1</accession>
    <name>A0A1Q2CGI1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10785</name>
        <name evidence="3" type="ORF">SAMN05428934_102148</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY52513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45221">
        <property type="protein sequence ID" value="AQP45221"/>
        <property type="gene ID" value="RPIT_10785"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY52513">
        <property type="protein sequence ID" value="SDY52513"/>
        <property type="gene ID" value="SAMN05428934_102148"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10785"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY52513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="231" mass="24368" checksum="4BB3BB98E11931FC" modified="2017-04-12" version="1">MSTNESPSPLTDPALSGLLRVGAWAAFGSVALIVVQVVVFALWPPVHSVAEVFALMTGNPVLGLVSLDLLYVANNLLVWLFYLGLGAALWPVSRSAVIVAVGLGTLQMAAYLASNPAVEMLAVARAHADADPSMRAVLESAGEALLAAWKGTAFLTYYFMGAFVLLILVWALRRSALFAPSTAWWALAAGLLMLVPSTFGTVGMLFALASLIPWSVLCLLAGRRLLRLSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGJ4</accession>
    <name>A0A1Q2CGJ4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_10460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45165">
        <property type="protein sequence ID" value="AQP45165"/>
        <property type="gene ID" value="RPIT_10460"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10460"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="201" mass="22961" checksum="21E71C29ADA7789F" modified="2017-04-12" version="1">MWLCMPCHYRIDADEEAFPTEVLVAWKLDHEKRVSELVGLDLEQSLLRLAGVRLHHDLARDLLQWLDGHRFMYFEDEREFPDQVWNAVQDLRWKISNLRGRVTDSGSPFGAVLAAIDDAVYQFMVALSDIRVSEITVTSGYPEFERFSEALSILRSGILEVSAPLARQEGFQFEKIPEYLMPKSDGDVVEIRSGLTSGGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGN7</accession>
    <name>A0A1Q2CGN7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Dihydrofolate reductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">Iron (Metal) dependent repressor, DtxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_11115</name>
        <name evidence="10" type="ORF">SAMN05428934_10281</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DtxR/MntR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY50447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11115"/>
    <dbReference type="EnsemblBacteria" id="AQP45276">
        <property type="protein sequence ID" value="AQP45276"/>
        <property type="gene ID" value="RPIT_11115"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY50447">
        <property type="protein sequence ID" value="SDY50447"/>
        <property type="gene ID" value="SAMN05428934_10281"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11115"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001367">
        <property type="entry name" value="Fe_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036421">
        <property type="entry name" value="Fe_dep_repressor_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038157">
        <property type="entry name" value="FeoA_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022687">
        <property type="entry name" value="HTH_DTXR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022689">
        <property type="entry name" value="Iron_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02742">
        <property type="entry name" value="Fe_dep_repr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01325">
        <property type="entry name" value="Fe_dep_repress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00529">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47979">
        <property type="entry name" value="SSF47979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50944">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH dtxR-type" evidence="8">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP45276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY50447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="229" mass="25561" checksum="C51644143293AAFF" modified="2017-04-12" version="1">MSDLIDTTEMYLRTVYELLEEGVVPLRARIAERLHQSGPTVSQTVARMERDGLLVVDADRTIKLTREGARLARDVMRKHRLAECLLTEVIGLEWEKVHDEACRWEHVISVDVEKRLLAILDQPTRSPYGNPIPGLRALGVEVPLTPFREGADPLIDELTDQPQRFVLVRMSENIQADASMLADLAHIGLRPGGIFEASRADGDVHLTVDGRDATIGLFAAELLFVSRHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGV2</accession>
    <name>A0A1Q2CGV2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_11530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11530"/>
    <dbReference type="EnsemblBacteria" id="AQP45349">
        <property type="protein sequence ID" value="AQP45349"/>
        <property type="gene ID" value="RPIT_11530"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11530"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="100" mass="10875" checksum="344F79244D58835B" modified="2017-04-12" version="1">MPALRATCATPSSGKSLQTRPVFHRKREPIEAHLTIVFAALAVARHLQDQTGVSIKRLVQTLRPLQSVTITIAGQPIQAQPRLTAEAEAILAKIPRRAGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGZ4</accession>
    <name>A0A1Q2CGZ4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycine/betaine ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_11735</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11735"/>
    <dbReference type="EnsemblBacteria" id="AQP45386">
        <property type="protein sequence ID" value="AQP45386"/>
        <property type="gene ID" value="RPIT_11735"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11735"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007210">
        <property type="entry name" value="ABC_Gly_betaine_transp_sub-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04069">
        <property type="entry name" value="OpuAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012523916" evidence="2">
        <location>
            <begin position="22"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="OpuAC" evidence="3">
        <location>
            <begin position="42"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="306" mass="32879" checksum="B7EB6FBFCE69F6E4" modified="2017-04-12" version="1">MRSMSRRFTLPVALVSVLALASCGGGDPLSTSEPDGSQPSQTIVVGSQDYYSNEIIAEAYAQALEAEGYTVDRQFRIGQREAYLPEIESGAIDLFPEYTGPLLQYWSPEPEERLSDEVYEALEGVVPDGLRVLDQSEATDQDSYTVTRAFADEWDLEQVSDLANVDTPLTLGANSEAESRPNGPQGLKDVYGVDAAFTPIEDGGGPLTVKALNDGDIQLAIIYTADPTIQENDLVSLEDDKGLFLASHVVPLASDDVDDAAASVINEVSDAMSAEDLVSLNARSVQEQLPAADIARDWLADEGLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH20</accession>
    <name>A0A1Q2CH20_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperone protein DnaK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">HSP70</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Heat shock 70 kDa protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Heat shock protein 70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dnaK</name>
        <name evidence="10" type="ORF">RPIT_11930</name>
        <name evidence="11" type="ORF">SAMN05428934_10689</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Acts as a chaperone.</text>
    </comment>
    <comment type="induction">
        <text evidence="6">By stress conditions e.g. heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11930"/>
    <dbReference type="EnsemblBacteria" id="AQP45419">
        <property type="protein sequence ID" value="AQP45419"/>
        <property type="gene ID" value="RPIT_11930"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92640">
        <property type="protein sequence ID" value="SDY92640"/>
        <property type="gene ID" value="SAMN05428934_10689"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11930"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="SSF100934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4 6 7" id="KW-0067">ATP-binding</keyword>
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    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
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        <location>
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            <end position="620"/>
        </location>
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            <end position="251"/>
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        <location>
            <begin position="594"/>
            <end position="612"/>
        </location>
    </feature>
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            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP45419.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY92640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="620" mass="66470" checksum="88224812C9A877EC" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH26</accession>
    <name>A0A1Q2CH26_9ACTN</name>
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
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        <source>
            <strain evidence="2 4">RP1T</strain>
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
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            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
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        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
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            <dbReference type="Pfam" id="PF03070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="AQP45407.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY92973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="229" mass="24970" checksum="7DFB35602602BDEC" modified="2017-04-12" version="1">MDWPTGTFSERAWAATAQIRERIDRLPLLLELADGTLEPARFVEYLAQDDVYLRGYTRAVAMLAARAPHSAAAQFWATSASGAVAAEVAMHASLLSDERLRDLPRSTTASGTTRAYVNSLLAATAFEPYAVGVAAVLPCFWVYADVGHRLASSAAHVADHPYGAWVAAYNDPAFQADTRRAISLLDEAADSADDATREAMLTAFINATHYEELFWGRSYAGERWSPVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH38</accession>
    <name>A0A1Q2CH38_9ACTN</name>
    <protein>
        <submittedName>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
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        <name evidence="13" type="ORF">SAMN05428934_10669</name>
    </gene>
    <organism evidence="12 14">
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1T</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">RP1</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY92162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12030"/>
    <dbReference type="EnsemblBacteria" id="AQP45439">
        <property type="protein sequence ID" value="AQP45439"/>
        <property type="gene ID" value="RPIT_12030"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92162">
        <property type="protein sequence ID" value="SDY92162"/>
        <property type="gene ID" value="SAMN05428934_10669"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12030"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004363">
        <property type="term" value="F:glutathione synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="GSHS_ATP-bd"/>
    </dbReference>
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        <property type="entry name" value="GSHS_N"/>
    </dbReference>
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        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21621:SF4">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0317">Glutathione biosynthesis</keyword>
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    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
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        <location>
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            <end position="330"/>
        </location>
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        <source>
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        </source>
    </evidence>
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        </source>
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        </source>
    </evidence>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP45439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDY92162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="347" mass="38037" checksum="E13439BDE6BAB036" modified="2017-04-12" version="1">MKIGFVVNDVMTEKAVYTTTRLAMQATNMGHDTWLLGMGDFAYEPDGSLSAKARGAKGSNYRSLERFLEDVQKPDMEEYITLSEFDVVMQRADPADDANQAPWANNAGVAFGQLIASTGTLVVNDPGSLANALSKAYFQHFPEVVRPRTLISRDESQITKFIKSLGGKAVLKPLQGSGGSGVFLVNTDESPNMSQIIEAIGRDGYIVAQEYLEEAKNGDVRMFVMNGKPLRVNGKYAAFRRRSSGSDLRSNMSAGGKAESVKVTDEMLRMVEVVRPKLVADGMFLVGLDIVGDKLMEVNVFSPGGLGSCQSLYEENFAAPIIEDLERKLEIRRHYNGQLRNIDLASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH48</accession>
    <name>A0A1Q2CH48_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12065</name>
        <name evidence="3" type="ORF">SAMN05428934_10662</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY92008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12065"/>
    <dbReference type="EnsemblBacteria" id="AQP45446">
        <property type="protein sequence ID" value="AQP45446"/>
        <property type="gene ID" value="RPIT_12065"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92008">
        <property type="protein sequence ID" value="SDY92008"/>
        <property type="gene ID" value="SAMN05428934_10662"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12065"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY92008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="682" mass="74866" checksum="7FDA94E21B60B4B7" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH51</accession>
    <name>A0A1Q2CH51_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein L16 Arg81 hydroxylase, contains JmjC domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_12020</name>
        <name evidence="4" type="ORF">SAMN05428934_10671</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12020"/>
    <dbReference type="EnsemblBacteria" id="AQP45437">
        <property type="protein sequence ID" value="AQP45437"/>
        <property type="gene ID" value="RPIT_12020"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92211">
        <property type="protein sequence ID" value="SDY92211"/>
        <property type="gene ID" value="SAMN05428934_10671"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12020"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039994">
        <property type="entry name" value="JmjC_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13096">
        <property type="entry name" value="PTHR13096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08007">
        <property type="entry name" value="Cupin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="13"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY92211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="374" mass="41136" checksum="03FBBB54B87340F0" modified="2017-04-12" version="1">MSQLDLLTGDAHAFLEEAWGRRIHVHTIPATELAGIFDIEQADHLITQTAIRTPQIRMAQDGSVLAESRYTRQATIAGKPMTGLIDSRKVLDLFADGATIVFQGLQRYWEPLRQLVRGLEQQLGHPCQANAYLTPPGSQGFALHSDSHDVIVFQTYGAKEWEVHDDNGARQVLMVPGTSMYLPTGTPHMARTQNTASLHVTLGINRYLWRDLVKKIVDPIVNSMDDPLPGNVFGDSASIAATLREKLDEVARQLAWSDTEQAVQQFEQTFLSGRQSVLGGGLMDRLSLPDVGLTSAIRRRAGSTCQLREDGDRLGLYLGDRVVTVPADLRDTVELVLAQEGAFTPALLGDQLDDGSAVVLVKRLIREGLLEVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH78</accession>
    <name>A0A1Q2CH78_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12155</name>
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    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45464">
        <property type="protein sequence ID" value="AQP45464"/>
        <property type="gene ID" value="RPIT_12155"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12155"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019719">
        <property type="entry name" value="DUF2599"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10783">
        <property type="entry name" value="DUF2599"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="408" mass="44182" checksum="BE3A096D47821805" modified="2017-04-12" version="1">MILVETRSLGSEAFVAEGDVAHVEVPVDPRSGVSVSDQDEGISISLPKNAVFSDGVPTDDGSVVFESVDGRTEGVVVEALDDGSVQLQTVLGGPEADHDLEYQLGVPAEARVELSENGTVLVFGADDSLLGGLATPWAVDATGADVKTYFSLEGAKVTQHVITGDSTAYPVTTDPWLGIALISSVTRKYDSVNGGSRFYVYPTWWGRGGAGAAARWSAWSEARSKGVWDNSSLRNQFYCHYDTRPVTTFKSSWNLENWRSDKGYWGFSCVVQLGRWANDSRKKRRSVGSHWSSRARSSDPWCGGGLRCRRGIGVRRGRRESRPHPGCGAVGSRRTFGTPAAGRGVRHVCPRSRTTRPGKGRRSDAVGCGRGSRNATFRAPWVADHRGIRLADRTGPFHAIDEAARLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHB0</accession>
    <name>A0A1Q2CHB0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_12060</name>
        <name evidence="4" type="ORF">SAMN05428934_10663</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY92034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45445">
        <property type="protein sequence ID" value="AQP45445"/>
        <property type="gene ID" value="RPIT_12060"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY92034">
        <property type="protein sequence ID" value="SDY92034"/>
        <property type="gene ID" value="SAMN05428934_10663"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12060"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045401">
        <property type="entry name" value="GAP1-M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045402">
        <property type="entry name" value="GAP1-N2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20014">
        <property type="entry name" value="GAP1-M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20013">
        <property type="entry name" value="GAP1-N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAP1-N2" evidence="1">
        <location>
            <begin position="8"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="GAP1-M" evidence="2">
        <location>
            <begin position="164"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY92034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="864" mass="93839" checksum="849FFA1062A467D2" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHD4</accession>
    <name>A0A1Q2CHD4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GntR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12540</name>
        <name evidence="3" type="ORF">SAMN05428934_104178</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY79959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12540"/>
    <dbReference type="EnsemblBacteria" id="AQP45529">
        <property type="protein sequence ID" value="AQP45529"/>
        <property type="gene ID" value="RPIT_12540"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY79959">
        <property type="protein sequence ID" value="SDY79959"/>
        <property type="gene ID" value="SAMN05428934_104178"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12540"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011663">
        <property type="entry name" value="UTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07702">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00866">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="25"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY79959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="254" mass="27927" checksum="E8F8F18513748CBA" modified="2017-04-12" version="1">MTSEPPMPQSKPYILQIEVDRDSTIPLHAQIAEPLAAAIESGEITPGTRIEDEVSMAERLKVSRPTARRAMETLTNRGLIVRRRGAGTQVTPTRIHRPMALSSLNDDLEKSGVEPRTSVLTWEVESATPGVAAALNLAVGADVVHMRRLRMLRDEPLAILTNWLPSEIAPSLAELESGGLYARLRERGIRVSIGVQQIGARLATQDEARLLNEPAGAALLTMQRTAYDESHKPVEFGMHVYRASMYSYDQTVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHG3</accession>
    <name>A0A1Q2CHG3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cell division protein FtsI</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Cell elongation-specific peptidoglycan D,D-transpeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_12705</name>
        <name evidence="5" type="ORF">SAMN05428934_104146</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY79037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12705"/>
    <dbReference type="EnsemblBacteria" id="AQP45559">
        <property type="protein sequence ID" value="AQP45559"/>
        <property type="gene ID" value="RPIT_12705"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY79037">
        <property type="protein sequence ID" value="SDY79037"/>
        <property type="gene ID" value="SAMN05428934_104146"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12705"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544499" evidence="2">
        <location>
            <begin position="32"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="3">
        <location>
            <begin position="155"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY79037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="475" mass="50671" checksum="97892493EA99AA64" modified="2017-04-12" version="1">MNGPIRKVTVFVSLLMAALLLNLTWIAVVRADSLNEDTSNRRVRDAEFSRNRGAILVGNQPIAQSVPRGGRFPYIRSYPQPEIWSSVTGWYSYDYARSGLEHTYNQELAGTSSGQSVGRAVDLLTGRRSRGANISTTLNPAAQAAAVRALGDQRGAVVAMNYETGEILALVSTPTYDPNRLATVDLTAEREAWVELLDRPDEPLKNRAVREIYPPGSTFKLVTAAAALEDGMVPSTEVDSPDSLPLPNSNRSMGNSTNCGGTRVSLEQALKTSCNTAFGNLGLQLGADKLLEQAEKFGFNQEPTIDMTAAESVFPTELDEAQTALTAIGQFDVAASPLQIVQVAAAIANDGVLMRPHVVSSVTNSDLTVLSSNPSERLSAPLSPSSAEHLQQMMIATVEDGTGRPAQIDGAVVGGKTGTAQTAPDRPPYAWFVGFAEEPKVAVVAFVEDADVERNDISGGRLAAPIFKAVVEALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHH0</accession>
    <name>A0A1Q2CHH0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH lacI-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_12760</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12760"/>
    <dbReference type="EnsemblBacteria" id="AQP45568">
        <property type="protein sequence ID" value="AQP45568"/>
        <property type="gene ID" value="RPIT_12760"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12760"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="13"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="344" mass="36238" checksum="F7084A1394199BCE" modified="2017-04-12" version="1">MRSRGADISMIRPTLEDVARYAGVSRATVSRVVRRDPNVASETVTKVDAAVAELGYVPNGAARSLATGRSNTLAMVVPEPDTRVFSDPFFGLAVAGINAGLAGTDMQLVMVFASRTDRAGAVVDFLLEGRVAGAIIVSHHRSDGLVAASLALPIPTVFLGAPLLPPGYDKTPYYVDTDNYGGARLAAERMVEMGVRRPATVAGPRDMAAALDRLHGWCETLEQAGLEVAVAHGDYTRASGARAAAQLLDADPTIDGIFAASDLMAQGVLDTLRERGIRIGDEVKVIGFDDFEAASQTVPPLTTVVNPAVELGRQATVMVLNLVKGRETPSPVMLPVELHIRASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHM5</accession>
    <name>A0A1Q2CHM5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pentapeptide repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_13010</name>
        <name evidence="2" type="ORF">SAMN05428934_10485</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45612">
        <property type="protein sequence ID" value="AQP45612"/>
        <property type="gene ID" value="RPIT_13010"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY77366">
        <property type="protein sequence ID" value="SDY77366"/>
        <property type="gene ID" value="SAMN05428934_10485"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13010"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13599">
        <property type="entry name" value="Pentapeptide_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY77366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="202" mass="21979" checksum="A357376A0CD36DF3" modified="2017-04-12" version="1">MNISDIRDDGTDYLAGETITGRLEPRDELRGVVFEGCTFTGCVLDEAVLRNCDFIDCRFDSCSLSQTKLPGTSFADCVLKGCRALSVAWTSVIAGTLSVAPLTFEGCKLTYSSFVGSTLRRWSFIDCDLSEADFSDAVLAATSFEHCNLAKARFVGADLRGVSLISSYNYYFDPREAKVAGLRVTPDGGAQLLRAFGIEVRE</sequence>
</entry>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        </source>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY76015.1"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
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    </evidence>
    <sequence length="68" mass="7413" checksum="D9AC52409A663DB3" modified="2017-04-12" version="1">MPIVVNLDIMLAKRKMSVTELSERVGVALPNISILKNGRAKAVRFTTLEAICAALDCQPGDLLEYVPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
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    </dbReference>
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        <property type="gene ID" value="SAMN05428934_10435"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
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        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="12"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY75955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="335" mass="34514" checksum="6313EEDEE1DF460F" modified="2017-04-12" version="1">MAEAGERSSRGVTRDDVARLAGVSVAVVSYVVNNGPRPVAEATRARVLDAIDRLGYRPNAAARSLTTGRSDLVGLIVPDVGNPYFAALAQAVETEARARGVNLVLVQGRAGQLAPLVESLSGHLVAGIITAAVPEAAAEEILRRDGIAMVRLSLAPSETGDGAVLPDFYSGALDATRHLIEVHGHRRVALVLGGEGPVGGLTDDRFRGWRDALAAAGLPTDAVIRAPWSLAGGRDAATRLVTDFPDCTAVFAGSDQQAIGLISGLHGLGRSIPADMAIASFDGSPEAKFTVPPLTTAGVPMAVLARAAVEGLFAPGRPAEAFRPDLVLRSSCGCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHR0</accession>
    <name>A0A1Q2CHR0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Catechol 2,3-dioxygenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Glyoxalase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_12905</name>
        <name evidence="9" type="ORF">SAMN05428934_104106</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the extradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY77930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12905"/>
    <dbReference type="EnsemblBacteria" id="AQP45595">
        <property type="protein sequence ID" value="AQP45595"/>
        <property type="gene ID" value="RPIT_12905"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY77930">
        <property type="protein sequence ID" value="SDY77930"/>
        <property type="gene ID" value="SAMN05428934_104106"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12905"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004462">
        <property type="term" value="F:lactoylglutathione lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019439">
        <property type="term" value="P:aromatic compound catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018146">
        <property type="entry name" value="Glyoxalase_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000486">
        <property type="entry name" value="Xdiol_ring_cleave_dOase_1/2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00082">
        <property type="entry name" value="EXTRADIOL_DIOXYGENAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00934">
        <property type="entry name" value="GLYOXALASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0058">Aromatic hydrocarbons catabolism</keyword>
    <keyword evidence="4 6 9" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="7">
        <location>
            <begin position="8"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="7">
        <location>
            <begin position="169"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY77930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="283" mass="30795" checksum="DA7936A97C77FC68" modified="2017-04-12" version="1">MTLASSTHMGRLELRVRDLGKQLTFYTEGVGLTPLADDAGAVTLGLGSTPVVRLTEAPDLRPARRNEAGLFHTAVVFDQLPALASSLVSMYQRYPETYAGTGDHLVSQAFYFTDPEGNGVELYHDRPREEWIWRGGQVQMATLYIDPNEFVATHLGEADPVDLSTASGTLGHVHLQVGDVPTAKSFYVDALGFEQTFELAGSALFVAAGGYHHHMAMNVWNSQGAGPRQNTLGMGVVDIVVPTAEEIAKADERLRFAGHTPTFDGRTLTVLDPWRNELRLSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI16</accession>
    <name>A0A1Q2CI16_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_13950</name>
        <name evidence="2" type="ORF">SAMN05428934_1118</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ11664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13950"/>
    <dbReference type="EnsemblBacteria" id="AQP45769">
        <property type="protein sequence ID" value="AQP45769"/>
        <property type="gene ID" value="RPIT_13950"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ11664">
        <property type="protein sequence ID" value="SDZ11664"/>
        <property type="gene ID" value="SAMN05428934_1118"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13950"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ11664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="238" mass="23885" checksum="C55AF8E9B7FAAD96" modified="2017-04-12" version="1">MDETIETAKDFGRIPVDRRTIARGIGWGVPAVMVLGATPAFAASGDTVTFGSVVVNDSPEGAPSNYYINESNLASTVTVSGTATPGATVTISATGGFSVGVVAAGGSWSYEIPAASLPQGTIACTAAVAGPPKVSVAGPNTVVKDTVAPTIASTTYQGTGSPKKLTFSGALVETTAVSGTVSITTDDGKTYSDQNVSYTAAPWTVTFEGISNNVNYTVTAVLRDAAGNSVTVEETGTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI51</accession>
    <name>A0A1Q2CI51_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_13985</name>
        <name evidence="2" type="ORF">SAMN05428934_1111</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000011">
        <property type="protein sequence ID" value="SDZ11487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13985"/>
    <dbReference type="EnsemblBacteria" id="AQP45774">
        <property type="protein sequence ID" value="AQP45774"/>
        <property type="gene ID" value="RPIT_13985"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ11487">
        <property type="protein sequence ID" value="SDZ11487"/>
        <property type="gene ID" value="SAMN05428934_1111"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13985"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ11487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="61" mass="6425" checksum="1A63B3C1D9B6C61F" modified="2017-04-12" version="1">MAPFLRALQQLDVPEPAITARLVAGVIESAMRLMESGGDPDAVTRTTLALVRAAVQPASHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIB2</accession>
    <name>A0A1Q2CIB2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hydroxyacid dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Uncharacterized zinc-type alcohol dehydrogenase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_14205</name>
        <name evidence="5" type="ORF">SAMN05428934_11223</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ14623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14205"/>
    <dbReference type="EnsemblBacteria" id="AQP45813">
        <property type="protein sequence ID" value="AQP45813"/>
        <property type="gene ID" value="RPIT_14205"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ14623">
        <property type="protein sequence ID" value="SDZ14623"/>
        <property type="gene ID" value="SAMN05428934_11223"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14205"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="3">
        <location>
            <begin position="14"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDZ14623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="350" mass="37270" checksum="CB800CBA21AFCD2A" modified="2017-04-12" version="1">MPDVAAYAIDSPTGRYERTTITRREPGPTEVYLDIAYAGICHSDIHTARGEWGKVNYPFVGGHEIAGVVSKVGSDVTKFKVGDRVGVGCFVDSCGECEMCLADEEQFCTSRPGTIATYASIGRDGEPTHGGYSQGITVEEDYLMRVPDETSLEHAAPLMCAGITLYSPLKRFGAGPGKRVGILGMGGLGHMGVQISAALGAETIVLSRTLAKRDDGLKLGADDYVSTEDRDAMKKLRGTFDLIISTISDGVDLDATLRLIKPHGTLVNLGLPEHPSTINLGSLIGGGKVLAGSQIGGIKETQEMLEFCAEHGINPVIEIIDADEINEAYDNVVASKVRYRYVIDAATIGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIB3</accession>
    <name>A0A1Q2CIB3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14405</name>
        <name evidence="3" type="ORF">SAMN05428934_11263</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ15367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14405"/>
    <dbReference type="EnsemblBacteria" id="AQP45851">
        <property type="protein sequence ID" value="AQP45851"/>
        <property type="gene ID" value="RPIT_14405"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ15367">
        <property type="protein sequence ID" value="SDZ15367"/>
        <property type="gene ID" value="SAMN05428934_11263"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14405"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ15367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="258" mass="28037" checksum="2E27CD64DFCBF42C" modified="2017-04-12" version="1">MASALITGGTSGIGHAFAREFASRGTDLILVARDEARLNAVAEELRQLHGVEVEVLPADLAVRDDVARVAARLEDQSRPVDWLVNNAGFGLHSTVLDPDDIDIHARALDVMCLAVLILGGAAARAMKERGHGRIVTVASSSSAIYTGNYSAIKAWARSYSNGLALELTGTGVTATALLPGWVRTEFHDRAGINASKIPDFIWIDPDKLVRECLDDAEKGKIESVPDWKWKLALKVGDHGPRTLTRWFTRVLTASRKRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIB4</accession>
    <name>A0A1Q2CIB4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_14505</name>
        <name evidence="7" type="ORF">SAMN05428934_109115</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ06794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14505"/>
    <dbReference type="EnsemblBacteria" id="AQP45869">
        <property type="protein sequence ID" value="AQP45869"/>
        <property type="gene ID" value="RPIT_14505"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ06794">
        <property type="protein sequence ID" value="SDZ06794"/>
        <property type="gene ID" value="SAMN05428934_109115"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14505"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="117"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ06794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="177" mass="18637" checksum="BCAC786F96812847" modified="2017-04-12" version="1">MAGETPITLIGNLTADPELRFTPNGAAVANFTVASTPRTFDRQTNEWKDGDAMFLNCSVWRQYAENVAESLQKGTRVIVSGRLKSRSYETREGEKRTVFEVDVDEVGPALRYATAKVTRTQGGGGGGGGSWQGNQGGGQPGGGQGGQSDPWGGTGTSGGNRGGNDPWAQSQPEEPPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIC9</accession>
    <name>A0A1Q2CIC9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetate kinase</fullName>
            <ecNumber evidence="6">2.7.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Acetokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ackA</name>
        <name evidence="8" type="ORF">RPIT_14420</name>
        <name evidence="9" type="ORF">SAMN05428934_109132</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>acetate + ATP = acetyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:11352"/>
            <dbReference type="ChEBI" id="CHEBI:22191"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Mg(2+). Can also accept Mn(2+).</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the acetokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.1" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ07126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14420"/>
    <dbReference type="EnsemblBacteria" id="AQP45854">
        <property type="protein sequence ID" value="AQP45854"/>
        <property type="gene ID" value="RPIT_14420"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ07126">
        <property type="protein sequence ID" value="SDZ07126"/>
        <property type="gene ID" value="SAMN05428934_109132"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14420"/>
    <dbReference type="UniPathway" id="UPA00340">
        <property type="reaction ID" value="UER00458"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008776">
        <property type="term" value="F:acetate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00020">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004372">
        <property type="entry name" value="Ac/propionate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000890">
        <property type="entry name" value="Aliphatic_acid_kin_short-chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023865">
        <property type="entry name" value="Aliphatic_acid_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21060">
        <property type="entry name" value="PTHR21060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00871">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000722">
        <property type="entry name" value="Acetate_prop_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00471">
        <property type="entry name" value="ACETATEKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00016">
        <property type="entry name" value="ackA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01075">
        <property type="entry name" value="ACETATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01076">
        <property type="entry name" value="ACETATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="204"/>
            <end position="208"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="277"/>
            <end position="279"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="325"/>
            <end position="329"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="379"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDZ07126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="393" mass="42163" checksum="26106697D74DB832" modified="2017-04-12" version="1">MSQILLLNCGSSSIKYQLLDPAQGSPQAVGIVQRIGQPMSTIDHEAGDAEYHDEEPFADHTEAVARVVRMFDEHGPSLDTVVAVGHRTVHGGSTFVESTLIDDEVIAHLEELSELAPLHNPPALAGIRAAQKVLPDVPHVAIFDTAFFSTLPAEAYTYAIDRQVTERLGVRKYGFHGTSHSYVSKEAAKFLDRPIEDLKIIVCHLGNGASISAVDGGVAVETSMGLTPLQGLVMGTRSGDVDPGLHKYLVRKGMTIDDVDTLLNKQSGMAGLCGYTDMRDVATQIHAGNEEAKLALDVYVHRLISYIGSYIAVLGGVDALVFTAGIGENAAHVRGPAVRRLAGLGFELDEEANKVRSKQAREISTPESKVRVLVIPTNEELAMAQETLQVIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIE2</accession>
    <name>A0A1Q2CIE2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14355</name>
        <name evidence="3" type="ORF">SAMN05428934_11253</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000012">
        <property type="protein sequence ID" value="SDZ15190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45843">
        <property type="protein sequence ID" value="AQP45843"/>
        <property type="gene ID" value="RPIT_14355"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ15190">
        <property type="protein sequence ID" value="SDZ15190"/>
        <property type="gene ID" value="SAMN05428934_11253"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14355"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ15190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="202" mass="19848" checksum="DDC963833EAC1FB7" modified="2017-04-12" version="1">MARHNRGQSPELAEGADDALAGDGADAGLTGLGADGALAGDIGESGLSGEAGLLADSGDTADLADAADFADAADRADAAVLALAALGATETVTCGAAAEAVAAGSLAAGVEADLADHGVSADWVVAGAALTVTLGASWVPRLSAIATAPAVAAPSPSVPEIAHVAMVRLEMFMVCSSRTRTGGRFLMSTTKHRRDEGRPRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIF1</accession>
    <name>A0A1Q2CIF1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DEDD_Tnp_IS110 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45853">
        <property type="protein sequence ID" value="AQP45853"/>
        <property type="gene ID" value="RPIT_14415"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14415"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="1">
        <location>
            <begin position="20"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="363" mass="39499" checksum="10F97B83C432F46E" modified="2017-04-12" version="1">MYKTSHTRRHRNPPSGSVVVGIDTHLDIHHAALVDAATGAPVADQQFPATPAGYLELLDWAADHGRVSRAGVEQTGTYGAGLTAVLHAAGIEVIEINHTERGDRARHGKTDELDAYRAATAAAAGTQKGLAKHYHPAIAALRPLMVLRAHHRSSRQRAWGRVGGMLVTCPDDLADQVRGLNSAQKRARIAAWRPDLTRLHDPVNSYKLALRDLARACLDHDRAIVEIDAQLLRILTPIAPTLLAQHHVGPVTTAQLLITAGHPGRITSGDAFAKLVGVAPLPVQSGKSSRWRLSRSGDRQANSVIHRVVIGRLGTDPRSKTYIQRRVSEGKTRSEAIRALKRHVTRDLWTALQTDLNNLPHTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIL1</accession>
    <name>A0A1Q2CIL1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH lacI-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_01080</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01080"/>
    <dbReference type="EnsemblBacteria" id="AQP45947">
        <property type="protein sequence ID" value="AQP45947"/>
        <property type="gene ID" value="RPIT_01080"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01080"/>
    <dbReference type="Proteomes" id="UP000188324">
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF53822"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="11"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="343" mass="36648" checksum="90A270935551E00C" modified="2017-04-12" version="1">MHPRIGPVSCTIEDVAKLAGVSKSTVSRVLTGSPKVSPAARQAVERAIAETGFRLNAHARSLASGRSDAIAVLLTQPTEELFDDPTIRGLSRGVNEGLGDREEALLVLLAGSPREQRRAVRFLDKQRIDGVVHLTPHHADPILPVVMAAKLPMVVCGTLPGVNLGPQIRTVTITDREGAASAVRYLRECGAKRIAAITGPKDAPGSSERLMGYRDALDDAYDPALVVHGDYTLPSGRDAMRSLLDSSVEFDAVFCASDRMAAGVYQVAQERGLSIPGDLQVVGFDGHPLGEQLVPTLTTVAQPIEYIGRQTVEMLNEMITGGDPGHRVFPTELVVRGSTRNPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIM5</accession>
    <name>A0A1Q2CIM5_9ACTN</name>
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        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">SAMN05428934_10953</name>
    </gene>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP45923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14835"/>
    <dbReference type="EnsemblBacteria" id="AQP45923">
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        <property type="gene ID" value="RPIT_14835"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05601">
        <property type="protein sequence ID" value="SDZ05601"/>
        <property type="gene ID" value="SAMN05428934_10953"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ05601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="170" mass="18057" checksum="BE19E8F1A8FFF289" modified="2017-04-12" version="1">MRRHLNLSLQALRSWSARRWAGAAVATLVVGLALGVVTVLIPNPIFGREIPPTAWSYPAWIVTSVLSGMLIATYLRSGPKATADAEDEKLSVWGTVGAFGAWFAIGCPVCNKIALLALGYTGALTYFGPLQPWLAALSLILLAVGLVFRLSGSIACAVPQRRRVSVAQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIP4</accession>
    <name>A0A1Q2CIP4_9ACTN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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        <name evidence="2" type="ORF">SAMN05428934_10957</name>
    </gene>
    <organism evidence="1 3">
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDZ05669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45920">
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        <property type="gene ID" value="RPIT_14815"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05669">
        <property type="protein sequence ID" value="SDZ05669"/>
        <property type="gene ID" value="SAMN05428934_10957"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14815"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ05669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="123" mass="14140" checksum="83877D7504196A11" modified="2017-04-12" version="1">MNDSHTTSWYWPPAFNDAKQLVEYYESVAIPDEALFRFAHAYTRRAVAEGATGIDTRIPPHLMQTVLRAAMMRGLAKYFPLPEQQKVDKYELHYVGGDQRTVKWIALHFKTDDLGFDALYGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIS7</accession>
    <name>A0A1Q2CIS7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="AQP46012"/>
        <property type="gene ID" value="RPIT_04275"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04275"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="113" mass="12160" checksum="7C74D58DB5994ABC" modified="2017-04-12" version="1">MRGMLGVDATAPRKAEGAHRAFRASVAVSGVRCLITYLLVPVLVPMASLAGWVAAPIGIALCVYAVINGIVSLKRFWSADHPHRWLYTFFMAVVFVILTAALISDFSRLGGLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIV0</accession>
    <name>A0A1Q2CIV0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45975">
        <property type="protein sequence ID" value="AQP45975"/>
        <property type="gene ID" value="RPIT_02180"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02180"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="88" mass="9012" checksum="1E8B98B242912B1E" modified="2017-04-12" version="1">MVCPVAPAGAQVLVDEFLGWFSWALVWVAFPAGILAAVAAVILGKVFSMPHVSKGGLIGVFVVLGAALLYLVIPGILSGFLGDGCVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ03</accession>
    <name>A0A1Q2CJ03_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0029 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IMPACT family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09415"/>
    <dbReference type="EnsemblBacteria" id="AQP46106">
        <property type="protein sequence ID" value="AQP46106"/>
        <property type="gene ID" value="RPIT_09415"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09415"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020569">
        <property type="entry name" value="UPF0029_Impact_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="PTHR16301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="UPF0029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00910">
        <property type="entry name" value="UPF0029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF0029" evidence="2">
        <location>
            <begin position="16"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="210" mass="22597" checksum="5440E22457D9639C" modified="2017-04-12" version="1">MDARPLEGTDVEIEIKRSRFLCRVRRVTTEAEAREVIEERRSVHFDARHHCSAFVLGPDGRTARSSDDGEPAGTAGVPMLQVLQKHGVSDVVAVVTRYFGGVKLGAGGLVRAYSEAVAAALEKAGTRRVELHRLLRVDVGYAEAGFIEEQLRGLTLPGGAEVTVDGVDWTDLAHIRLAIPDGSEGEFAQTLAAVSTGRLSAEPIGERWVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ24</accession>
    <name>A0A1Q2CJ24_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein translocase subunit SecD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secD</name>
        <name evidence="11" type="ORF">RPIT_06310</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06310"/>
    <dbReference type="EnsemblBacteria" id="AQP46050">
        <property type="protein sequence ID" value="AQP46050"/>
        <property type="gene ID" value="RPIT_06310"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06310"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01463_B">
        <property type="entry name" value="SecD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005791">
        <property type="entry name" value="SecD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00916">
        <property type="entry name" value="2A0604s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01129">
        <property type="entry name" value="secD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="413"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="442"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="94"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP46050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="513" mass="53420" checksum="16E381D111319B47" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ88</accession>
    <name>A0A1Q2CJ88_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_13740</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_13740"/>
    <dbReference type="EnsemblBacteria" id="AQP46177">
        <property type="protein sequence ID" value="AQP46177"/>
        <property type="gene ID" value="RPIT_13740"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_13740"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012507">
        <property type="entry name" value="YibE_F"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41771">
        <property type="entry name" value="PTHR41771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07907">
        <property type="entry name" value="YibE_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010319154" evidence="3">
        <location>
            <begin position="27"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="344"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP46177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="388" mass="39995" checksum="92A9499A04D38C5B" modified="2017-04-12" version="1">MVGFLAVVGVLAVAGLIWLWPTGAEVDGALNRIGDPPGVTYEDATITAIAAGCTSVEAPGGDLTCETATVELDSGSEAGQAADIELIGPQVHHGLRAGDSIEVMRLPTPDGVHYSFSGINRLPVLLTMLALFVVAVVAVARWRGLMALVGLAVAGYVLLGFMLPAIIVGKPGMAVALAGSTAIMFIVLYVAHGISLRTSAALAGTLLGLAVTTALGAIAVGAARLSGFAEENEYDLAQLAPGIDFQELLMVGIIIGGLGVLNDVTITQASAVWELRAAAPEWTRRRVFMSGMRIGRDHIASTIYTIVFAYAGSALAVLLLLYFTNREAIDLFGLELFAGESVRTLASAIGLILSVPITTGIAAITVGPGRPVPETPRHADPVAPDPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJA2</accession>
    <name>A0A1Q2CJA2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6457 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_10845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10845"/>
    <dbReference type="EnsemblBacteria" id="AQP46130">
        <property type="protein sequence ID" value="AQP46130"/>
        <property type="gene ID" value="RPIT_10845"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10845"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045598">
        <property type="entry name" value="DUF6457"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20058">
        <property type="entry name" value="DUF6457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6457" evidence="1">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="87" mass="8850" checksum="D831BDF899DDD61C" modified="2017-04-12" version="1">MELWHAWLANATDEVGGSVAEIPIDALLDLAAAVANDVARPMAPVSAFVAGLAAGRGADAEAVASALTRLAKAWPEKGTGRNLPSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CB76</accession>
    <name>A0A1Q2CB76_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sirohydrochlorin ferrochelatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00025</name>
        <name evidence="4" type="ORF">SAMN05428934_10940</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00025"/>
    <dbReference type="EnsemblBacteria" id="AQP43407">
        <property type="protein sequence ID" value="AQP43407"/>
        <property type="gene ID" value="RPIT_00025"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05365">
        <property type="protein sequence ID" value="SDZ05365"/>
        <property type="gene ID" value="SAMN05428934_10940"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002762">
        <property type="entry name" value="CbiX-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01903">
        <property type="entry name" value="CbiX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDZ05365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="226" mass="23332" checksum="FEA57BD0193AD648" modified="2017-04-12" version="1">MSGPATLIIALHGTRHRPGTEFAEQLRAAVSAELPGVPVELGWVDIHDELLAETVQRFERSVIVPAFLAAGYHVEHDVRDAVAASGGRAVATDHVGPDLVRAIGDRLLAAGPLGDAVVLAAIGSKRPGATAEVHAAARRLSQLVGRPVEPGFIYASEPTLEAAAEKLRAQGHLTLSVATHALAPGLYQRHTAALGVPTVADPIGTHPLLVSAIVGRYATAALAQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBF3</accession>
    <name>A0A1Q2CBF3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00255</name>
        <name evidence="2" type="ORF">SAMN05428934_1056</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY83538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_061613716.1">
        <property type="nucleotide sequence ID" value="NZ_FNPU01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43443">
        <property type="protein sequence ID" value="AQP43443"/>
        <property type="gene ID" value="RPIT_00255"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY83538">
        <property type="protein sequence ID" value="SDY83538"/>
        <property type="gene ID" value="SAMN05428934_1056"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00255"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY83538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="76" mass="8348" checksum="D5E68FC957BF0528" modified="2017-04-12" version="1">MIDDCIDVEDGGCAGPVELRQTMSGSGASFPRCELHYEIYAERMAAVIAEISARYPVTPPADWSPLDAGEAWDEQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBH7</accession>
    <name>A0A1Q2CBH7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alanine racemase</fullName>
            <ecNumber evidence="3">5.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_00370</name>
        <name evidence="8" type="ORF">SAMN05428934_10528</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-alanine = D-alanine</text>
            <dbReference type="Rhea" id="RHEA:20249"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="5.1.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the alanine racemase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY84152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00370"/>
    <dbReference type="EnsemblBacteria" id="AQP43458">
        <property type="protein sequence ID" value="AQP43458"/>
        <property type="gene ID" value="RPIT_00370"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY84152">
        <property type="protein sequence ID" value="SDY84152"/>
        <property type="gene ID" value="SAMN05428934_10528"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00370"/>
    <dbReference type="UniPathway" id="UPA00042">
        <property type="reaction ID" value="UER00497"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030632">
        <property type="term" value="P:D-alanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01201">
        <property type="entry name" value="Ala_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000821">
        <property type="entry name" value="Ala_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011079">
        <property type="entry name" value="Ala_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020622">
        <property type="entry name" value="Ala_racemase_pyridoxalP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00842">
        <property type="entry name" value="Ala_racemase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00992">
        <property type="entry name" value="ALARACEMASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01005">
        <property type="entry name" value="Ala_racemase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00492">
        <property type="entry name" value="alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00395">
        <property type="entry name" value="ALANINE_RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_C" evidence="6">
        <location>
            <begin position="243"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for D-alanine" evidence="3">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for L-alanine" evidence="3">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3 4">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600821-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600821-52"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY84152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="371" mass="39500" checksum="F0F81942C54943C0" modified="2017-04-12" version="1">MPTPTQLRVDLEAIHANLALARDRANGRSVLAAVKANAYGHGLVPVARSIQERGSADWLGVALTSEAEELRAAGITLPILKFTPTLADDLDDAITAELTLSVGDAGAIRAAQLAAAARGRIVEVHLKIDTGMRRVGAEPGDAALLGAQLADSPNLRVGGIFTHLPVSDVPEGGEFTRAQFRLFDDVVADVERVVGTVPLVHCANSGAVLGHDLGRSTMVRPGIMIYGSYPDPHTPRDHPLSDVARWTSRITFVKRVQAGQTVGYGRTWTAPVDTWVATVAVGYGDGYSRLLSSRGRMLVDGHSYPVIGRVCMDQTMIDLGPDLPTVGVGDEVVLLGTSGKERIGVEEIAELMGTITYEVTCLITDRVPRVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBI1</accession>
    <name>A0A1Q2CBI1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH tetR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_00395</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43462">
        <property type="protein sequence ID" value="AQP43462"/>
        <property type="gene ID" value="RPIT_00395"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00395"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="15"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP43462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="204" mass="21955" checksum="582FEE143367FB67" modified="2017-04-12" version="1">MARTDRTPRTRMAADARRDDILAGAAAAFRARPYADVRVADVAEGVGASPALVYRYFTSKAGLYAAVVQAADDALASQQRSAVASLPTGSPPRDKVRALLEAYLDHVAADPTSWTNPFLAGDEPPEALAVREEGRLRHVADLRASLGLTPDAWARHEMSLHGYLGFVDQACLRWANSECSPDLRWAVIEASLGALEGALGDWRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBP9</accession>
    <name>A0A1Q2CBP9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10 14">Catalase</fullName>
            <ecNumber evidence="3 10 14">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">RPIT_00805</name>
        <name evidence="18" type="ORF">SAMN05428934_105114</name>
    </gene>
    <organism evidence="17 19">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 19" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">RP1T</strain>
        </source>
    </reference>
    <reference evidence="18 20" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">RP1</strain>
        </source>
    </reference>
    <reference evidence="17" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Serves to protect cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 14">
            <text>2 H2O2 = 2 H2O + O2</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10 12">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the catalase family. HPII subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="3 10 14"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00805"/>
    <dbReference type="EnsemblBacteria" id="AQP43536">
        <property type="protein sequence ID" value="AQP43536"/>
        <property type="gene ID" value="RPIT_00805"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86448">
        <property type="protein sequence ID" value="SDY86448"/>
        <property type="gene ID" value="SAMN05428934_105114"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00805"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03132">
        <property type="entry name" value="GATase1_catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1370.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024712">
        <property type="entry name" value="Catalase_clade2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043156">
        <property type="entry name" value="Catalase_clade2_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041399">
        <property type="entry name" value="Catalase_large_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42821">
        <property type="entry name" value="PTHR42821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18011">
        <property type="entry name" value="Catalase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038927">
        <property type="entry name" value="Catalase_clade2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="SSF56634"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 13" id="KW-0349">Heme</keyword>
    <keyword evidence="9 10 14" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="8 10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="6 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 10 14" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase" evidence="16">
        <location>
            <begin position="82"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="15">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="412"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="416"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="423"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR038927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="AQP43536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="SDY86448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="756" mass="81531" checksum="B2394F445A551837" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBR1</accession>
    <name>A0A1Q2CBR1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Uncharacterized conserved protein, DUF302 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_00830</name>
        <name evidence="3" type="ORF">SAMN05428934_105119</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY86582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_00830"/>
    <dbReference type="EnsemblBacteria" id="AQP43541">
        <property type="protein sequence ID" value="AQP43541"/>
        <property type="gene ID" value="RPIT_00830"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY86582">
        <property type="protein sequence ID" value="SDY86582"/>
        <property type="gene ID" value="SAMN05428934_105119"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00830"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005180">
        <property type="entry name" value="DUF302"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035923">
        <property type="entry name" value="TT1751-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016796">
        <property type="entry name" value="UCP021774"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03625">
        <property type="entry name" value="DUF302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF021774">
        <property type="entry name" value="UCP021774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103247">
        <property type="entry name" value="SSF103247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF302" evidence="1">
        <location>
            <begin position="35"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY86582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="130" mass="13927" checksum="EBABF969B647337F" modified="2017-04-12" version="1">MNYALRIDLERPFDEVVGLTKESLAESGFGILTEINLKQTLKNKLDVDIDDQVILGACNPGFAHKGLQTEPSLGLLLPCNVVVRHSAGVTVVEAIDPETMVTLTGNSQMEPLADEVRAALKAALDRVAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CBU2</accession>
    <name>A0A1Q2CBU2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_00995</name>
        <name evidence="2" type="ORF">SAMN05428934_105150</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000005">
        <property type="protein sequence ID" value="SDY87435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43571">
        <property type="protein sequence ID" value="AQP43571"/>
        <property type="gene ID" value="RPIT_00995"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY87435">
        <property type="protein sequence ID" value="SDY87435"/>
        <property type="gene ID" value="SAMN05428934_105150"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_00995"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY87435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="289" mass="31637" checksum="BB2D40820A581FED" modified="2017-04-12" version="1">MPHPTQQMVGDIVAMTDPVVRNVAITTCYRDLALAVADVVGRRDVNWLAFGAWASGTAGRAIRGEGLPIDWGTSRAVAEGNRTIIADVAPRFVRWLDEVARAGGPSRTALEVALGDAIFETTPELADALVAYQTAVELRELTGDAPADEEADQALAELMLLGNVKVAAHEQHIADDLIDDAMPLGGLFGRITTRFVEVITPDGPLDVCRDVPLPSYLGGLKYPSVLAHLTRDDLCELAERFDHAPDGEVIESRATTWECYDERMGYIFCFFRAFARDARYFDVPAEFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CC28</accession>
    <name>A0A1Q2CC28_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Phosphatidylinositol phosphate synthase</fullName>
            <shortName evidence="10">PIP synthase</shortName>
            <ecNumber evidence="10">2.7.8.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">CDP-diacylglycerol--D-myo-inositol-3-phosphate 3-phosphatidyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_01620</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 10">
            <text>1,2-di-(9Z-octadecenoyl)-sn-glycero-3-cytidine-5'-diphosphate + 1D-myo-inositol 3-phosphate = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:61216"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:85356"/>
            <dbReference type="ChEBI" id="CHEBI:144472"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 10">
            <text>1D-myo-inositol 3-phosphate + a CDP-1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60504"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58088"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Contains a di-nuclear catalytic Mg(2+) center.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Phospholipid metabolism; phosphatidylinositol phosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10 11">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.-" evidence="10"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01620"/>
    <dbReference type="EnsemblBacteria" id="AQP43668">
        <property type="protein sequence ID" value="AQP43668"/>
        <property type="gene ID" value="RPIT_01620"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01620"/>
    <dbReference type="UniPathway" id="UPA00220"/>
    <dbReference type="UniPathway" id="UPA00575"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02241">
        <property type="entry name" value="PIP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044268">
        <property type="entry name" value="PIP_synthase_PgsA1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="151"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>a CDP-1,2-diacyl-sn-glycerol</name>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>a CDP-1,2-diacyl-sn-glycerol</name>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>a CDP-1,2-diacyl-sn-glycerol</name>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP43668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="204" mass="21129" checksum="E69D8610DDE3871A" modified="2017-04-12" version="1">MLSFLRGAYGRALTPLAGLLLRVGLTPTAVTVVGTLGVAVASLWLLPQGRWALAFFIIGAFLLADGLDGTMARLGGRESRFGAFLDSTLDRVADGAVFAGFAIWAALHDTATMWLALGALVMGFVVSYARARAEVEGWDASTGLFERTDRLVIAGAGALAVDLGAPLWVLTAALSLVALGSAITAGQRIAAAWRQSKGPDAPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCC0</accession>
    <name>A0A1Q2CCC0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">MFS transporter, NNP family, nitrate/nitrite transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_02155</name>
        <name evidence="8" type="ORF">SAMN05428934_10129</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY23168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02155"/>
    <dbReference type="EnsemblBacteria" id="AQP43762">
        <property type="protein sequence ID" value="AQP43762"/>
        <property type="gene ID" value="RPIT_02155"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY23168">
        <property type="protein sequence ID" value="SDY23168"/>
        <property type="gene ID" value="SAMN05428934_10129"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02155"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
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        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="PTHR23515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="404"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="432"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP43762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY23168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="462" mass="50010" checksum="1E1DD6EB3883D654" modified="2017-04-12" version="1">MSTKLETKGDWLQSWDPEDPEKWDQKLAWNTLTVTTFTLTLAFVAWFLPSAIVPKLNALGFTFTKAQLYWMAAMPGLSGGLLRLVWMVLPPKIGTRKMVTLTTLLLILPVLGWGFEVTNPDVPYWRLMGLAILSGIGGGAFSGFMPSTSYFFPKRLQGTALGLQAGIGNFGVSLVQLLTPWLISFGMFGFLGSQTMTTAGASDVVVWYQNSALVYLPFIVAGAIWAYIVLRSVPVKANIKQQFDIFSNQDTWWMTILYIMTFGTFSGLSAQFGLLMLNLYGSGNSAIVEGAGSTATILIEGYTLPDPVKFVFLGPLVGAGARVVFSPLTDKMGGAIWTLISGIGVLASILFTIPALTPDLSSAEALQGDFNQFLWGMLAIFLFSGIGNASTFKQMPMIFEKRQAGGVIGWTAAIAAFGPFLFGVGLTIMSPTLFYIIGAVWAVGCIAITWFRYARPGAPKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCD3</accession>
    <name>A0A1Q2CCD3_9ACTN</name>
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        <submittedName>
            <fullName evidence="7">Carbohydrate ABC transporter membrane protein 2, CUT1 family</fullName>
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        <submittedName>
            <fullName evidence="6">Sugar ABC transporter permease</fullName>
        </submittedName>
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    <gene>
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        <name evidence="7" type="ORF">SAMN05428934_10116</name>
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    <organism evidence="6 8">
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY22772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02095"/>
    <dbReference type="EnsemblBacteria" id="AQP43750">
        <property type="protein sequence ID" value="AQP43750"/>
        <property type="gene ID" value="RPIT_02095"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY22772">
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        <property type="gene ID" value="SAMN05428934_10116"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02095"/>
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        <property type="component" value="Chromosome"/>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="MetI-like"/>
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    </dbReference>
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        <property type="entry name" value="SSF161098"/>
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    </dbReference>
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        <property type="entry name" value="ABC_TM1"/>
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    </dbReference>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="4" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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            <end position="109"/>
        </location>
    </feature>
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        <location>
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            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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            <end position="181"/>
        </location>
    </feature>
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        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
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        <location>
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            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="84"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY22772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="297" mass="32546" checksum="4F2A331B426C4AD8" modified="2017-04-12" version="1">MAKKRVVLENENDTRLRGGRWWAQVGWKHVLAVAMIVYCIFPILYVLSASLNEGGTLTGSNQLFRSFSLVNYQELMDSDFVRWMLHSFYVSSVTAIGTVVMGAAAAYAFSRFRFTGRRGGLTALLIIQMFPQMLAFVAIFLLALLIGDIFPALGVGSHLQLILIYLGGALGSNTFLMYGFFNTIPHELNEAAKIDGATHAQIFWGIIMRLVTPILAVVGLLSFVGSYGEFILARIVLARPENYTLAVGLYVWGSDERNAPWGLFAAGAVLAAIPIILLFMYLQKYIVSGLTAGGVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCD4</accession>
    <name>A0A1Q2CCD4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_02175</name>
        <name evidence="2" type="ORF">SAMN05428934_10134</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY23325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43766">
        <property type="protein sequence ID" value="AQP43766"/>
        <property type="gene ID" value="RPIT_02175"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY23325">
        <property type="protein sequence ID" value="SDY23325"/>
        <property type="gene ID" value="SAMN05428934_10134"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02175"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY23325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="245" mass="24631" checksum="C4E88AE14C2F01CB" modified="2017-04-12" version="1">MTTATFSLAELRAAYTALHAGAFTTDPTPQPETATAAVAELPAAAADAVVGVVGVSGGVGTTTVALAIAEALAAGRLVELSVPHTSGLAAASSAELGTQHGWSIGSRDGLRLERRTDPDATILPDTAAGVTVLDLGAWAEPLPAVSVLVVVASCSVPSVRRLNARLEVLHGLRVVPVITGVPGRALPKPVGSVCGPRLRAAAADGLLLLVPECASLRVGGVTADPLPRRLQSAVDVIKSCVEEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCE8</accession>
    <name>A0A1Q2CCE8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_02310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP43792">
        <property type="protein sequence ID" value="AQP43792"/>
        <property type="gene ID" value="RPIT_02310"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02310"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP43792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="74" mass="8170" checksum="FCD21CF04F21E402" modified="2017-04-12" version="1">MLIELYTPVQYLCQMIVPFASAFLSVHDREVNPVLTADIEPVQLPSAWARSGVRAIQVARAPAAAIFLSLERNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCN6</accession>
    <name>A0A1Q2CCN6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-oxoacid:ferredoxin oxidoreductase subunit beta</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">2-oxoglutarate ferredoxin oxidoreductase subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_02715</name>
        <name evidence="3" type="ORF">SAMN05428934_101143</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY26563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_02715"/>
    <dbReference type="EnsemblBacteria" id="AQP43861">
        <property type="protein sequence ID" value="AQP43861"/>
        <property type="gene ID" value="RPIT_02715"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY26563">
        <property type="protein sequence ID" value="SDY26563"/>
        <property type="gene ID" value="SAMN05428934_101143"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02715"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPP_enzyme_C" evidence="1">
        <location>
            <begin position="61"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY26563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="347" mass="37495" checksum="41572AF2A9929052" modified="2017-04-12" version="1">MTQGLAGVPLSLEPLTKKDYTSDQEVRWCPGCGDYAVLATFQSMMATLGIKRENTVIISGIGCSSRFPYYVDTYGMHSIHGRAPSIATGVAISRPDLNVWVVTGDGDALSIGGNHLMHTLRRNVNVTIMLFNNRIYGLTKGQYSPTSELGKVTKSTPYGSLDTPFNPVSLALGAEATFVARTIDSDRKHLAEVLTAAAEHRGASLVEIYQNCPIFNDDAFATLKGPDGVLISLRHGEPIVFGGGEYCVIRDAQGEIRVAPTADVDPSHIVVHDETRTDPSQAFALSRLTEPGVLRQAPIGIFRRVERPTYDDLVRDQIAAVKADDTEAALKSVIAGSATWEAHERPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCT7</accession>
    <name>A0A1Q2CCT7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03020"/>
    <dbReference type="EnsemblBacteria" id="AQP43911">
        <property type="protein sequence ID" value="AQP43911"/>
        <property type="gene ID" value="RPIT_03020"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03020"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="1">
        <location>
            <begin position="8"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="191" mass="20342" checksum="87217C27104AC14C" modified="2017-04-12" version="1">MNPSRRSPLLAVDFETTGLTPGVDHVISVGMVDVDGFRIPLGTATNFLVDPGVGVGQSAIIHQLTDDELLAKGATPEEALDRVFGRLAGRILLAHHAAIEVGFLAAAVKRLYGITIEIPVVDTLGLGHRALGFGEDHPRDALRLWKLRVRAGLPSYKGHDAVVDALACAELYLALAQELDLTTLGQAIRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCV3</accession>
    <name>A0A1Q2CCV3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_03100</name>
        <name evidence="7" type="ORF">SAMN05428934_101221</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY28908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03100"/>
    <dbReference type="EnsemblBacteria" id="AQP43926">
        <property type="protein sequence ID" value="AQP43926"/>
        <property type="gene ID" value="RPIT_03100"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY28908">
        <property type="protein sequence ID" value="SDY28908"/>
        <property type="gene ID" value="SAMN05428934_101221"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03100"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY28908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="252" mass="25173" checksum="C4EAD7E872601BA2" modified="2017-04-12" version="1">MAWPWAIPLGLLIGAVLGAIGGGGAILTVPALIYIFGQGAGAATTGALIIVGLTSLVGVIPHQRDGNVRWREGLTFALLGIAGAAAGSIASVRVPDTVLTAAFSVLMLVVAAVMLRRLRGTRPDPQRKGWLAVIATATAVGLLTGFFGVGGGFAIVPALTLVLGFSMPAAVGTSLLVISINAATALGTRLLGGTGGLDWPLLLAFSVTAAAGSLLGARVGKRLGPRVLTISFVVLMIAVGLLMAAGSIPELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCW4</accession>
    <name>A0A1Q2CCW4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">30S ribosomal protein S14 type Z</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">rpsN</name>
        <name evidence="5" type="synonym">rpsZ</name>
        <name evidence="6" type="ORF">RPIT_03155</name>
        <name evidence="7" type="ORF">SAMN05428934_101232</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03155"/>
    <dbReference type="EnsemblBacteria" id="AQP43937">
        <property type="protein sequence ID" value="AQP43937"/>
        <property type="gene ID" value="RPIT_03155"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29290">
        <property type="protein sequence ID" value="SDY29290"/>
        <property type="gene ID" value="SAMN05428934_101232"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03155"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01364_B">
        <property type="entry name" value="Ribosomal_S14_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_S14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043140">
        <property type="entry name" value="Ribosomal_S14/S29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_S14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023053">
        <property type="entry name" value="Ribosomal_S14_Z"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836">
        <property type="entry name" value="PTHR19836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2 5" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP43937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY29290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="61" mass="6963" checksum="FBA0EC547DB2AC3A" modified="2017-04-12" version="1">MAKTALKVKQSRKPKFGVRAYTRCQRCGRPHSVYRKFGLCRICLRELAHAGELPGVTKSSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCZ4</accession>
    <name>A0A1Q2CCZ4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sugar kinase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Sugar or nucleoside kinase, ribokinase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03245</name>
        <name evidence="3" type="ORF">SAMN05428934_101250</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY29811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03245"/>
    <dbReference type="EnsemblBacteria" id="AQP43950">
        <property type="protein sequence ID" value="AQP43950"/>
        <property type="gene ID" value="RPIT_03245"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY29811">
        <property type="protein sequence ID" value="SDY29811"/>
        <property type="gene ID" value="SAMN05428934_101250"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03245"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="1">
        <location>
            <begin position="62"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY29811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="379" mass="40822" checksum="9F41586E50CFA5AD" modified="2017-04-12" version="1">MTNDHDHADDGGICEFCWAWDPLADTRREGDPPLDVLTTGPLFFDIIFTGLPRLPEPGEELHSAGMGSCPGGIANFATAAARLGLRTGLVAGFGDDAYGDWMWETLEGQEKINLSASRRFENFHSAITVSMAFHGDRGMVTHSHPLPEDLDDNYLAAPAARAATVDLASNSSWWHSMRDRGTLLFADLGFDETGKWDQSVLARLSECHAFTPNAVEAMNYTRTDRPTDAVRKLAELVPLAVVTDGPSGSYAIDQSTGEEAFCPSVTVDAIDPTGAGDVFAASIVLGTLAGWPLEHRLRFASLSSSLAVRQFGGSLAAPGWGDIADWWRQGSRRAADGDLKAAFVLRDYAFLADLIPEHQVQGVRRAQGTFASASDAGRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CCZ5</accession>
    <name>A0A1Q2CCZ5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03460</name>
        <name evidence="3" type="ORF">SAMN05428934_101292</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP43988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY31124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03460"/>
    <dbReference type="EnsemblBacteria" id="AQP43988">
        <property type="protein sequence ID" value="AQP43988"/>
        <property type="gene ID" value="RPIT_03460"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY31124">
        <property type="protein sequence ID" value="SDY31124"/>
        <property type="gene ID" value="SAMN05428934_101292"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03460"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="97"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP43988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY31124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="246" mass="26865" checksum="B03C230488AE95D2" modified="2017-04-12" version="1">MLADPVDQRTLLTLADLDSEVARVQHAARSLPQHKVIADLMAARQRVTDELVASVTAVDDLGVAVRKAESDLVPVRARLERDQQRVSDGSISDGKVLRSLTEEVEHLKRRINSLEDDELELMGRLEDATAHRDKVAAQKAEIESRLRDEVAARDAAVKKLSQEAKDLAATRAPIAAKMPADLLALYEKLRASSGMGAALLRAGRCGGCQLQLTLSDLDSYRRAPADQVIRCAECDRILVRTAESGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CD89</accession>
    <name>A0A1Q2CD89_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_03885</name>
        <name evidence="3" type="ORF">SAMN05428934_101381</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
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    </reference>
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    </dbReference>
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            <begin position="1"/>
            <end position="22"/>
        </location>
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            <begin position="23"/>
            <end position="211"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="AQP44061.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY33607.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="211" mass="22489" checksum="7CCEFAD62EA24EC1" modified="2017-04-12" version="1">MRYLRPVAAAILALFVASCATVRETPGDPSVAPSPTETLTILVDLPHYESVEDLASAADAIVKARVISSRSDLDLPDYTSDDPRVNPYIGASEAPSPEEIKAMGIPITVYTVEITESLAGKLSERSTIEVVEMGGLVDGVDHRVANLQPLATSKPDLLFLEEVRDGRYATVGMAQGRFTALSDGSYVSLSDTPLKIGTSADLQRLEQVVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
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    <name>A0A1Q2CDA6_9ACTN</name>
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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            <strain evidence="2 4">RP1T</strain>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="SAMN05428934_101350"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
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        <location>
            <begin position="42"/>
            <end position="69"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <end position="107"/>
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            <end position="131"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="160"/>
            <end position="181"/>
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            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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            <dbReference type="EMBL" id="AQP44035.1"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="SDY32790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="210" mass="21791" checksum="C96862ACF191DD01" modified="2017-04-12" version="1">MWEPAVGAALLAVAVLAWVVPRVRVADPEAPDFASLSTPWSWIAIAATTLLAGLVAGVEPLHWMLWLPYLGLGAPLVYVDLRTTWLPKRLHWLAAAGMAAGWIAVALTDWRTAVAAAAGAAAAGLFLYTAWRVTAALGFGDVRLAFLVGAVAGLGGASGWAASLLAGTVLGAVHGIAHALWARRDRARPAHFPYGPALWLGPIVAQAIAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDD3</accession>
    <name>A0A1Q2CDD3_9ACTN</name>
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        <submittedName>
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        </submittedName>
    </protein>
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        <lineage>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase M3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY36105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP44132">
        <property type="protein sequence ID" value="AQP44132"/>
        <property type="gene ID" value="RPIT_04315"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY36105"/>
        <property type="gene ID" value="SAMN05428934_101468"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04315"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
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        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
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        <property type="entry name" value="PTHR43660"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
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            <begin position="226"/>
            <end position="656"/>
        </location>
    </feature>
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        <location>
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            <end position="322"/>
        </location>
    </feature>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP44132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY36105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="663" mass="73443" checksum="BBC35DFECE3125A1" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDD4</accession>
    <name>A0A1Q2CDD4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nitric oxide reductase subunit B</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Nitric-oxide reductase large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_04295</name>
        <name evidence="4" type="ORF">SAMN05428934_101464</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
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            <taxon>Bacteria</taxon>
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    </organism>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY36002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_04295"/>
    <dbReference type="EnsemblBacteria" id="AQP44128">
        <property type="protein sequence ID" value="AQP44128"/>
        <property type="gene ID" value="RPIT_04295"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY36002">
        <property type="protein sequence ID" value="SDY36002"/>
        <property type="gene ID" value="SAMN05428934_101464"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_04295"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
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</entry>
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</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDT9</accession>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
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            <authorList>
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                <person name="Schumann P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 7">RP1T</strain>
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    <reference evidence="6 8" key="2">
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                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
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    <reference evidence="5" key="3">
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
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    </dbReference>
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        <property type="protein sequence ID" value="SDY40486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="RPIT_05180"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY40486"/>
        <property type="gene ID" value="SAMN05428934_101642"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PLP_homeostasis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PTHR10146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004848">
        <property type="entry name" value="YBL036c_PLPDEIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00044">
        <property type="entry name" value="TIGR00044"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_N" evidence="4">
        <location>
            <begin position="8"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1 2">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR004848-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY40486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="227" mass="23988" checksum="2452DDF53BEC1327" modified="2017-04-12" version="1">MTVTENLRSVRTRIDDACRAAGRDPSSVTLLPVSKYHGIDQIREAHRAGYALFGENRVQEMAEKSEALAGEGIGFAVIGRVQTNKAKQVAELAAELHSLDSLRLATALQRRLQGLGRRLPVLVQVNTSGEPQKGGIEPSEAPEFAKQLAGLDALVPMGLMTMAVNSPDRAVVAACFATLAAVQAALRDTTGGGWDELSMGMSGDFPIAIEHGATTVRLGTAIFGPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CDU2</accession>
    <name>A0A1Q2CDU2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_05155</name>
        <name evidence="4" type="ORF">SAMN05428934_101637</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000001">
        <property type="protein sequence ID" value="SDY40354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05155"/>
    <dbReference type="EnsemblBacteria" id="AQP44276">
        <property type="protein sequence ID" value="AQP44276"/>
        <property type="gene ID" value="RPIT_05155"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY40354">
        <property type="protein sequence ID" value="SDY40354"/>
        <property type="gene ID" value="SAMN05428934_101637"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05155"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY40354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="298" mass="31047" checksum="06432466B937ECC5" modified="2017-04-12" version="1">MTQQENPQPGPDGHAAVPAPLAAHFPLREADPLKVGDFWLDSRLTAGPAGVTFSAHEDGGDSVMLMLLSEGAAADPAARARFSGEINAMHIDTVVARGGEGQQDGRMGVRYRDSAAAPQLGQHSAQAPWAALAFDGSLAAVQEADRVLQAIDLSRTPPLSEPSGPDYRLHWIDKTAPGPSRQWPLAWPTRKDRAGWITVLTSFLLMVLLTFLALLLAILVFQNQPPVNAPQPIPSPASGEGSGSGEPQSGEPSQSGEGSGSPEPSPGQDGGPYSDSPSMNQPSGDQTGPGAPSPNPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CE70</accession>
    <name>A0A1Q2CE70_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methionine biosynthesis protein MetW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_06000</name>
        <name evidence="2" type="ORF">SAMN05428934_103146</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY68874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06000"/>
    <dbReference type="EnsemblBacteria" id="AQP44419">
        <property type="protein sequence ID" value="AQP44419"/>
        <property type="gene ID" value="RPIT_06000"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY68874">
        <property type="protein sequence ID" value="SDY68874"/>
        <property type="gene ID" value="SAMN05428934_103146"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06000"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010743">
        <property type="entry name" value="Methionine_synth_MetW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07021">
        <property type="entry name" value="MetW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02081">
        <property type="entry name" value="metW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY68874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="196" mass="21816" checksum="78A393CBBD1977C1" modified="2017-04-12" version="1">MRRDLELISTLIPEGSRVLDLGCGDGTLLAMLRDRGCSGTGVDVNPDDVIAALRAGVDVIELDLDSQLGEFADDSYDFVVLSRTLQTVHRPRAVLAEMGRIAVHSVVSMPNFAHWRNRLRLLRGRMPMSRDLPFDWYDTPNLHHASLPDLEPLFASVRMKIDRRIPLDAEGRPHRLGNVAANLAASSSLYVLHAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CED8</accession>
    <name>A0A1Q2CED8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 10">Histidinol dehydrogenase</fullName>
            <shortName evidence="10">HDH</shortName>
            <ecNumber evidence="5 10">1.1.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">hisD</name>
        <name evidence="17" type="ORF">RPIT_06380</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>H2O + L-histidinol + 2 NAD(+) = 3 H(+) + L-histidine + 2 NADH</text>
            <dbReference type="Rhea" id="RHEA:20641"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10 15">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10 11 16">Belongs to the histidinol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.23" evidence="5 10"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06380"/>
    <dbReference type="EnsemblBacteria" id="AQP44484">
        <property type="protein sequence ID" value="AQP44484"/>
        <property type="gene ID" value="RPIT_06380"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06380"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00014"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004399">
        <property type="term" value="F:histidinol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06572">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01024">
        <property type="entry name" value="HisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001692">
        <property type="entry name" value="Histidinol_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022695">
        <property type="entry name" value="Histidinol_DH_monofunct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="PTHR21256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000099">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00083">
        <property type="entry name" value="HOLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00069">
        <property type="entry name" value="hisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00611">
        <property type="entry name" value="HISOL_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7 10 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13" id="KW-0520">NAD</keyword>
    <keyword evidence="9 10 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 15" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="10 12">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10 12">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 14">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 14 15">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 14 15">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 14">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 14 15">
        <location>
            <position position="364"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 14">
        <location>
            <position position="418"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 14 15">
        <location>
            <position position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR000099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="AQP44484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="432" mass="45298" checksum="B176520C3729E296" modified="2017-04-12" version="1">MLRTLDFTDADGAYRSRLPRPNFDVEAAVDVVRPIVEGVARHGEQALSEFSQRFDHVVPDQFRVPADALVRAADDLDPQLAEAFTEAIRRRRQVAKALELEPEMPAVTLADGARVGLRNIPVDRVGLYVPGGLAPLASSVIMNVIPAQVAGVRSIAVASPPQRDFGGLPHPNILALCHLLGVDEVYAVGGAQAVAMFAHGVEGLCEPVSLITGPGNIYVVAAKRLVRGLVGIDSEAGPTEIAIVADDTANPAYVAADLISQAEHDPMAASVLITPSVDLADAVQGELATQVAKTRHRDRVTTALTGQQSAIVLVRDIDQAVAVADAYAAEHLEIQTADASAVAARIGNAGAIFVGDFSPVSLGDYSAGSTHVLPTAGCACHSSGLTVRSFVRTVHVIDYSRGALLEVADGVERFALAEDLPGHAAAISVRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CEF8</accession>
    <name>A0A1Q2CEF8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Prolyl oligopeptidase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">S9 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_06535</name>
        <name evidence="4" type="ORF">SAMN05428934_103252</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000003">
        <property type="protein sequence ID" value="SDY71658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44509">
        <property type="protein sequence ID" value="AQP44509"/>
        <property type="gene ID" value="RPIT_06535"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY71658">
        <property type="protein sequence ID" value="SDY71658"/>
        <property type="gene ID" value="SAMN05428934_103252"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06535"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023302">
        <property type="entry name" value="Pept_S9A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02897">
        <property type="entry name" value="Peptidase_S9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9_N" evidence="2">
        <location>
            <begin position="13"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="1">
        <location>
            <begin position="479"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY71658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="684" mass="76022" checksum="609C6693969FFF5F" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CER1</accession>
    <name>A0A1Q2CER1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histidinol-phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Histidinol-phosphate phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">RPIT_06825</name>
        <name evidence="12" type="ORF">SAMN05428934_11081</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L-histidinol phosphate = L-histidinol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14465"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="3.1.3.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 8/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.15" evidence="5"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000010">
        <property type="protein sequence ID" value="SDZ09709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_06825"/>
    <dbReference type="EnsemblBacteria" id="AQP44560">
        <property type="protein sequence ID" value="AQP44560"/>
        <property type="gene ID" value="RPIT_06825"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ09709">
        <property type="protein sequence ID" value="SDZ09709"/>
        <property type="gene ID" value="SAMN05428934_11081"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06825"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00013"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004401">
        <property type="term" value="F:histidinol-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011809">
        <property type="entry name" value="His_9_proposed"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02067">
        <property type="entry name" value="his_9_HisN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP44560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDZ09709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="263" mass="28843" checksum="F2742AC2ADF68791" modified="2017-04-12" version="1">MAVAKDLNDDLRLAHLMADDADSLSMNRFRALDLQFSAKPDATPVTEADTAVEQSIRRTLARTRPRDAVHGEEFDDTGESARRWIIDPIDGTKNYLRGVPVWATLIALEVEGRVVASVVSAPALNRRWWATEGGGAFTGRSIMSASELRVSRVEELADSSLSYSDIAEWVDAGNGQGFVNLMRDCWRTRAYGDFWSYMLVAEGSVDIACEPELELYDMAALDVIVREAGGRFTNLSGEDGVRGPGALATNGLLHDKVLGYLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CET1</accession>
    <name>A0A1Q2CET1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">RPIT_07110</name>
        <name evidence="15" type="ORF">SAMN05428934_11022</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1T</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1</strain>
        </source>
    </reference>
    <reference evidence="14" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RP1T</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Phospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07110"/>
    <dbReference type="EnsemblBacteria" id="AQP44611">
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        <property type="gene ID" value="RPIT_07110"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ08439">
        <property type="protein sequence ID" value="SDZ08439"/>
        <property type="gene ID" value="SAMN05428934_11022"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07110"/>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008444">
        <property type="term" value="F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004570">
        <property type="entry name" value="Phosphatidylglycerol_P_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Phos_ph_gly_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
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        <location>
            <begin position="85"/>
            <end position="110"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="138"/>
            <end position="155"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00005074"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP44611.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDZ08439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="197" mass="22199" checksum="3C2B9EBD5F64DB64" modified="2017-04-12" version="1">MTEKPRRVKPSNWNVPNVLTVLRIVLVPVFVVLLFMEPENQFWRLMATLVFIVAMLTDLADGHIARKYNLITDFGKLWDPVADKALTGAAFVSLSILGELPWFFTIIILLREWGITWVRAAIAKYGIMAANKGGKLKTLTQTFALILFSLWLPGLPGAVQVLAWLLMWAALILTVVTGIDYLKHAWAIRRKGKAEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
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    <name>A0A1Q2CEW0_9ACTN</name>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
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            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="RPIT_07320"/>
    </dbReference>
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        <property type="gene ID" value="SAMN05428934_11421"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ18158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="221" mass="25143" checksum="412DBCB6C7032DE7" modified="2017-04-12" version="1">MTALFGELLVTRWRTQQHDRWTRTQLDDHRQRMLARLRDHAAPQSPYYADQHRGMQRAALSQLPPLTKTQLMAQWDRLVTSPELRLDSVTRRLQDLESGGGDPGQPWQGRWWTAATAGSAGQRGVFVWNRREWIRILSSYARVNDWAQVKVGPRRPVPTAIVSTRNPTHQSAVVGASLRNPLVPTLTTAWGVTLLVDSRYQEGTTRRDVIDTQEVHPGVQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF14</accession>
    <name>A0A1Q2CF14_9ACTN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">SAMN05428934_1218</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000021">
        <property type="protein sequence ID" value="SDZ22723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44693">
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        <property type="gene ID" value="RPIT_07635"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ22723">
        <property type="protein sequence ID" value="SDZ22723"/>
        <property type="gene ID" value="SAMN05428934_1218"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07635"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP44693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDZ22723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="332" mass="36398" checksum="FE6E53210D27910F" modified="2017-04-12" version="1">MFSTWQQVPLKASWGRVEPGAVLLFTDDEAVVVDARRSPQERSKVRLRIQRPNGERFERDVKSGETLRAQARALLPHGEYRAMALPAVIWHEDALFSPRNVAALLASAVVTTTFVVIVSRGSNAFAFVYLAFLIAGATAMAVRKRWKGGKLTLMAPERLGLTMATVHDYALTREAGKLWVPPTPGSDRRGLAVRRVAAIRDSYLALREDIAYRIECSALFDPKVPATAVFEEALVAFEDVTDLTPTDEVDALATEVELAFNVAQANAERIGLSHLPEDKRADARRAGKAAHLAAGAATEGERQASLAQVKRILDSLALYYLPTIREKPALEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF25</accession>
    <name>A0A1Q2CF25_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YD repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_07790</name>
        <name evidence="2" type="ORF">SAMN05428934_11823</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000018">
        <property type="protein sequence ID" value="SDZ21622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44719">
        <property type="protein sequence ID" value="AQP44719"/>
        <property type="gene ID" value="RPIT_07790"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ21622">
        <property type="protein sequence ID" value="SDZ21622"/>
        <property type="gene ID" value="SAMN05428934_11823"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07790"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDZ21622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="270" mass="27298" checksum="D4466905C926B5AA" modified="2017-04-12" version="1">MTNTAETTGVHTIAALLTGVGVSGGYAVGVVALVPLPEPLPDEPASTDTAGDLARVGDALETVATKLDATAASLSGDAAEMVGAAGRMAWVEADGAGRLEFSRDAAGRVLAATGSAGTQQWAYTGNLVVSHTGTATGAEVGTTVERDEDGRVAAVVRDGVRTEGTHDAAGQLVAARSGDVVHTWSWDAAGRLVAETAAGRTTTHTYGPSGQLATRETDGVAAHYTYDRAGRRTSEVGPDGRIEFTWGDLGWLTSVTGPQGRLLVPAGSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CF60</accession>
    <name>A0A1Q2CF60_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ca-activated chloride channel family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_07835</name>
        <name evidence="6" type="ORF">SAMN05428934_1137</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000013">
        <property type="protein sequence ID" value="SDZ16123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_07835"/>
    <dbReference type="EnsemblBacteria" id="AQP44727">
        <property type="protein sequence ID" value="AQP44727"/>
        <property type="gene ID" value="RPIT_07835"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ16123">
        <property type="protein sequence ID" value="SDZ16123"/>
        <property type="gene ID" value="SAMN05428934_1137"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07835"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5014544460" evidence="3">
        <location>
            <begin position="26"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="641"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="4">
        <location>
            <begin position="35"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP44727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDZ16123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="666" mass="69336" checksum="73A894D5B268CD72" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFE5</accession>
    <name>A0A1Q2CFE5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0102 protein RPIT_08545</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_08545</name>
        <name evidence="4" type="ORF">SAMN05428934_10720</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
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    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0102 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY96577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08545"/>
    <dbReference type="EnsemblBacteria" id="AQP44834">
        <property type="protein sequence ID" value="AQP44834"/>
        <property type="gene ID" value="RPIT_08545"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY96577">
        <property type="protein sequence ID" value="SDY96577"/>
        <property type="gene ID" value="SAMN05428934_10720"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08545"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00048">
        <property type="entry name" value="UPF0102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003509">
        <property type="entry name" value="UPF0102"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34039">
        <property type="entry name" value="PTHR34039"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP44834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY96577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="122" mass="13948" checksum="A2FB6242AE5B37A2" modified="2017-04-12" version="1">MESQRQSLGREGERRAAEHLERLGWTILERNWRCGDGEIDIVAYDPEASAIVVVEVKTRAGTGYGTPLETITYAKARRLRGLAAVYMRRSRRRAPRLRVDGVGVLLTRGEWTISHAQRIDEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFI2</accession>
    <name>A0A1Q2CFI2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_08795</name>
        <name evidence="2" type="ORF">SAMN05428934_10769</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY97713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44876">
        <property type="protein sequence ID" value="AQP44876"/>
        <property type="gene ID" value="RPIT_08795"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY97713">
        <property type="protein sequence ID" value="SDY97713"/>
        <property type="gene ID" value="SAMN05428934_10769"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08795"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY97713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="119" mass="12457" checksum="CE163580C4C61623" modified="2017-04-12" version="1">MVEGLVEVQHQVASPGCAVDDGEVQARRSLETIGELRATSANSASSVTIRAAGAMSKRPSPPVQVWSEGMMSGAVFGWAVADGANDVGPAARAAAIPIAAQTPQWRLWHRFHGSSKVLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFP1</accession>
    <name>A0A1Q2CFP1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">RPIT_09215</name>
        <name evidence="10" type="ORF">SAMN05428934_107155</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1T</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPF0702 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000007">
        <property type="protein sequence ID" value="SDY99369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09215"/>
    <dbReference type="EnsemblBacteria" id="AQP44942">
        <property type="protein sequence ID" value="AQP44942"/>
        <property type="gene ID" value="RPIT_09215"/>
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        <property type="gene ID" value="SAMN05428934_107155"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DUF421"/>
        <property type="match status" value="1"/>
    </dbReference>
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            <end position="31"/>
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        <location>
            <begin position="38"/>
            <end position="57"/>
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    </feature>
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        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
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            <dbReference type="ARBA" id="ARBA00006448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AQP44942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDY99369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="177" mass="18296" checksum="2BD5CFEABE0476A2" modified="2017-04-12" version="1">MWYSSLDPILRVLMVGPVAYLLAVVAIRISGKRALSKLNAFDLVVTVALGSMLATILTSSDLALATGLTGIALLLGLQVVVSLITSRFVKGQTAVRAEPTLLVRRGELLEEAVVSARLTEAEVLQAIRAAGFGGLDQLAAVCLESDGSLSVVGSDSLGDGTALSTVGSWDSDPESGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
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    <name>A0A1Q2CFU5_9ACTN</name>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
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                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="SAMN05428934_107116"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="69"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="100"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="146"/>
        </location>
    </feature>
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            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP44915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY98558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="172" mass="18913" checksum="62F2FC49B38A6468" modified="2017-04-12" version="1">MTATPIPRNSLGEWGYRLLWLGIGALPAVILLIRRISTEQGLVWFLFMVLGVPAMVIAQALAAMMAWVYRQRQWRHWLGSRTAVASYVYYGLWALLALSMPDGERGEVYLSPLQRLLGAGAGEVLSTMFLWATGAAYVATLVGIVWEGERAVATDPSGLTVKAIIASAFDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
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        <dbReference type="NCBI Taxonomy" id="1610493"/>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP44983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY60102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP44983">
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        <property type="gene ID" value="RPIT_09460"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY60102">
        <property type="protein sequence ID" value="SDY60102"/>
        <property type="gene ID" value="SAMN05428934_102414"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="43"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="AQP44983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY60102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="88" mass="9619" checksum="CB54EFE1353ED9C4" modified="2017-04-12" version="1">MAKGSIKVLGKNKIALALAFFVDAVNTRLIFHMPTDFFERWTGAPDPYLPDPDDPAWTDPDHQPPDTRAGPEEAILATSPATTEPITT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFV4</accession>
    <name>A0A1Q2CFV4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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        <name evidence="1" type="ORF">RPIT_09090</name>
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            <taxon>Bacteria</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <property type="term" value="F:oxidoreductase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP44925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="217" mass="22979" checksum="1C7727278A9DEFC1" modified="2017-04-12" version="1">MGASSGLGAALGLKHRERGDGVVALGRRGTRLAQLGDISNAYPGTWESVAADLTDPQGFTSCVERASTCDRVYLCAASNGDVEETMNLNFIVQARLAVALDRPGLRLVVISSLAAKVVFKEMPHYCASKAALEHWIAGHRQGASASIIVVRPGQFDSEFHTGPRDLRIERLPHERASEVARVADGRSEGTVTLGGLRDRVAAAVAGAIGPVNARRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CFX9</accession>
    <name>A0A1Q2CFX9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methylmalonyl-CoA carboxyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Propionyl-CoA carboxylase carboxyltransferase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_09655</name>
        <name evidence="4" type="ORF">SAMN05428934_102374</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY59055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09655"/>
    <dbReference type="EnsemblBacteria" id="AQP45019">
        <property type="protein sequence ID" value="AQP45019"/>
        <property type="gene ID" value="RPIT_09655"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY59055">
        <property type="protein sequence ID" value="SDY59055"/>
        <property type="gene ID" value="SAMN05428934_102374"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09655"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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</entry>
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</entry>
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    <accession>A0A1Q2CFZ6</accession>
    <name>A0A1Q2CFZ6_9ACTN</name>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
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    </evidence>
    <sequence length="516" mass="55620" checksum="F163B4934B70087C" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG16</accession>
    <name>A0A1Q2CG16_9ACTN</name>
    <protein>
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        <submittedName>
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    <gene>
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    <reference evidence="3 5" key="2">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY57723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09885"/>
    <dbReference type="EnsemblBacteria" id="AQP45059">
        <property type="protein sequence ID" value="AQP45059"/>
        <property type="gene ID" value="RPIT_09885"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY57723">
        <property type="protein sequence ID" value="SDY57723"/>
        <property type="gene ID" value="SAMN05428934_102329"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09885"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="322"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY57723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="409" mass="47134" checksum="2E77C180812EC79C" modified="2017-04-12" version="1">MRHMSSARRVIGRVTTTVLLLQIVAMLALTLVESMRKKKRKLRKFPITEPSPIDVGPDEVSVYTYGEHLYEDMVKAIDCAEEYVFFETYIWKGDEVGQQFRSALIRAANRGVRVYAIWDEFANLVVPRSFYKEIPDNVRVMPHPAIPIPWSPRSWGRDHRKLLTVDGKVGFIGGYNIGHLYARGWRDTHARVVGPGVAELDNAYIDFWNLHAGRSRERIDHNPPRSWEPGVRVHRNTPRIQVYPIRNMYLEAIDRATSHIWLTHAYLIPDDDLVASLRDAASRGVDVRIIVPERSNHVVADWLSRGYYTELLRSGIRLFLYQGAMVHSKTATIDGHWSTIGTANLDRLSLWGNYEINLEVTDTDVAAHMERVFATDQANTYELTEERWQQRSPVAKATELFLSPWRPLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG50</accession>
    <name>A0A1Q2CG50_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Peptide/nickel transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">RPIT_10020</name>
        <name evidence="9" type="ORF">SAMN05428934_102302</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1T</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">RP1</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10020"/>
    <dbReference type="EnsemblBacteria" id="AQP45083">
        <property type="protein sequence ID" value="AQP45083"/>
        <property type="gene ID" value="RPIT_10020"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56985">
        <property type="protein sequence ID" value="SDY56985"/>
        <property type="gene ID" value="SAMN05428934_102302"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10020"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="243"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="122"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AQP45083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY56985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="325" mass="35702" checksum="2BE023A4B328AAF7" modified="2017-04-12" version="1">MTQDPNNTLAEREEHEQYSIEDDVETTNTKSYSQGQLVRRRFIRHKGAMVSLAVLLFILLLAFTSIGVGPLPGWWDKNYLDTYAPVNGGKPTLQLWPFQIGEHPMGQNTIGKDYFALVMKGAQQSLFIAFMVGLLATFIGTAIGSIAGFYRGFAEAFLMRMTDLFIIIPTLVLAAVLGRMAGSSIFLLALVLGLVSWTGLARLVRGEVLSLREREFVAAARAVGTPAPRIIVRHILPNALGTIVVNATLLISAAILLETALSFLGFGVKPPNTSLGLLVSEFQNALTTRPWLFWWPGMFILAIALCVNFIGDGLRDAFDPRQQMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG63</accession>
    <name>A0A1Q2CG63_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">4-hydroxy-tetrahydrodipicolinate synthase</fullName>
            <shortName evidence="9">HTPA synthase</shortName>
            <ecNumber evidence="4 9">4.3.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dapA</name>
        <name evidence="11" type="ORF">RPIT_10155</name>
        <name evidence="12" type="ORF">SAMN05428934_102274</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:34171"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="4.3.3.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the DapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.7" evidence="4 9"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY56244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10155"/>
    <dbReference type="EnsemblBacteria" id="AQP45108">
        <property type="protein sequence ID" value="AQP45108"/>
        <property type="gene ID" value="RPIT_10155"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY56244">
        <property type="protein sequence ID" value="SDY56244"/>
        <property type="gene ID" value="SAMN05428934_102274"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10155"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00017"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00950">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00418">
        <property type="entry name" value="DapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005263">
        <property type="entry name" value="DapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020625">
        <property type="entry name" value="Schiff_base-form_aldolases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020624">
        <property type="entry name" value="Schiff_base-form_aldolases_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00674">
        <property type="entry name" value="dapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00665">
        <property type="entry name" value="DHDPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00666">
        <property type="entry name" value="DHDPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="site" description="Part of a proton relay during catalysis" evidence="9">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <feature type="site" description="Part of a proton relay during catalysis" evidence="9">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP45108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY56244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="300" mass="31573" checksum="F0E9AAC298F9C765" modified="2017-04-12" version="1">MAESDMTPVFGRLLTAMVTPFTSDGAEVDYAQVARLASHLVDDLGHDGLVVNGTTGESPTTTDEEKRRVLDAVVTAVGDRASIVAGVGTFSTRHSIELARQAAEVGVDGLLVVTPYYSRPPADALEDHFVAVADATELPVMLYDIPHRAGIPIPEDMLIRLDAHPRIRAVKDAKANIVSSSAVLSRTNLAYYAGDDAFLLPLLSVGGVGVVGTSTHFTASAAREIIDHYLAGRVEEAILANQHALPAFQGVFATQGCMMVKATLEARGFDVGACRPPMGKAPADAVASYVSLLEDLGFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CG90</accession>
    <name>A0A1Q2CG90_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetyl-CoA carboxylase, carboxyltransferase component</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Methylmalonyl-CoA carboxyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_10235</name>
        <name evidence="4" type="ORF">SAMN05428934_102258</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY55805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10235"/>
    <dbReference type="EnsemblBacteria" id="AQP45123">
        <property type="protein sequence ID" value="AQP45123"/>
        <property type="gene ID" value="RPIT_10235"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY55805">
        <property type="protein sequence ID" value="SDY55805"/>
        <property type="gene ID" value="SAMN05428934_102258"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10235"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="2">
        <location>
            <begin position="261"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY55805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="514" mass="55579" checksum="C9EBF4A74F8D5FC4" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGB8</accession>
    <name>A0A1Q2CGB8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ArsR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_10405</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10405"/>
    <dbReference type="EnsemblBacteria" id="AQP45154">
        <property type="protein sequence ID" value="AQP45154"/>
        <property type="gene ID" value="RPIT_10405"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10405"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13404">
        <property type="entry name" value="HTH_AsnC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="9"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="166" mass="18097" checksum="FDD90750970448E2" modified="2017-04-12" version="1">MKSARLPELDSVDWAILELLQVDATMPNKEIAANVGVAPSTCLERIRRMRRNGAIVATRAYVAPSLLGKGEQAFLGIQIRPHARETANDFVQKALALPETLALYNVSGSDDYLVHVAVADSTELQTLIIDKILALPQVAHCRTQLIFGEPWVAPLRHRPAAGALRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGK1</accession>
    <name>A0A1Q2CGK1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">4-diphosphocytidyl-2-C-methyl-D-erythritol kinase</fullName>
            <shortName evidence="8">CMK</shortName>
            <ecNumber evidence="2 8">2.7.1.148</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ispE</name>
        <name evidence="11" type="ORF">RPIT_10945</name>
        <name evidence="12" type="ORF">SAMN05428934_102114</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1T</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">RP1</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57823"/>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.148"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 3/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the GHMP kinase family. IspE subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.148" evidence="2 8"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY51484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10945"/>
    <dbReference type="EnsemblBacteria" id="AQP45248">
        <property type="protein sequence ID" value="AQP45248"/>
        <property type="gene ID" value="RPIT_10945"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY51484">
        <property type="protein sequence ID" value="SDY51484"/>
        <property type="gene ID" value="SAMN05428934_102114"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10945"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00094"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050515">
        <property type="term" value="F:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF08544">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ispE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5 8 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="9">
        <location>
            <begin position="93"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="10">
        <location>
            <begin position="208"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00009684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012052"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AQP45248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY51484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="299" mass="30647" checksum="0CB99ABAD4FF9A70" modified="2017-04-12" version="1">MTNSVRVRVPAKVNLALRVGGTDEQGFHELGTVFQAVSLGDEVRATTALPGQFRLSFLGEGAAFLPTDDGNLAIRAAKLLARHFERTDVGVSMVIRKRIPVAGGMAGGSADAAAVLVACNALWDLGATRSQLHDLAAALGSDVPFLLMGGTAIGTGRGVDLTPVLTDGTYHWTFALSHAGLSTPAVFKEFDRISAPRPTEIPAELLEGLRVGDAHKVGAALINDLEEAAISLQPTLAHTLKIGLEAGALGAIVSGSGPTCAFLAGSDGHAAELAEALGVFSGVRAVRRAHGPVAGAQVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGL5</accession>
    <name>A0A1Q2CGL5_9ACTN</name>
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        <submittedName>
            <fullName evidence="3">FmdB family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Putative regulatory protein, FmdB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_11035</name>
        <name evidence="4" type="ORF">SAMN05428934_10296</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP45262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY50901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11035"/>
    <dbReference type="EnsemblBacteria" id="AQP45262">
        <property type="protein sequence ID" value="AQP45262"/>
        <property type="gene ID" value="RPIT_11035"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY50901">
        <property type="protein sequence ID" value="SDY50901"/>
        <property type="gene ID" value="SAMN05428934_10296"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11035"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
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    </dbReference>
    <dbReference type="InterPro" id="IPR013429">
        <property type="entry name" value="Regulatory_FmdB_Zinc_ribbon"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY50901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="89" mass="9502" checksum="5D971EC31211B14C" modified="2017-04-12" version="1">MPTYQYRCTECGTDLEVVQKFTDDALTVCPDCDGELRKVFNAVGVVFKGSGFYATDSRKSKTASTKSASPAAEKAAPKTEAPKVEAKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGR5</accession>
    <name>A0A1Q2CGR5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphate-specific transport system accessory protein PhoU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_11320</name>
        <name evidence="6" type="ORF">SAMN05428934_10239</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Plays a role in the regulation of phosphate uptake.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PhoU family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY49207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11320"/>
    <dbReference type="EnsemblBacteria" id="AQP45312">
        <property type="protein sequence ID" value="AQP45312"/>
        <property type="gene ID" value="RPIT_11320"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY49207">
        <property type="protein sequence ID" value="SDY49207"/>
        <property type="gene ID" value="SAMN05428934_10239"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11320"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:cellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028366">
        <property type="entry name" value="P_transport_PhoU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42930">
        <property type="entry name" value="PTHR42930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003107">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02135">
        <property type="entry name" value="phoU_full"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PhoU" evidence="4">
        <location>
            <begin position="17"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="PhoU" evidence="4">
        <location>
            <begin position="122"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR003107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY49207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="221" mass="24556" checksum="FD65E3562A848C1F" modified="2017-04-12" version="1">MRTSYHEELDSILDSLVHMAGLVEVAIRDASESLLSADLGLAESVISKDIELDRMHEEMEYKCLSLLALQAPVAGELRTIVSAIRVVFELARMGDLAAHVAKIARLRYPATAVPERFEAGFREMASIAIEIIDLARLSMAARDVKGAHRLAEIDSRMDELRREQFTLMLSEDSDISIEGAVDVALLGRYFERFADHAVAVGRRVIYIMTGQVPEGEDWPNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGT1</accession>
    <name>A0A1Q2CGT1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoglycerate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_11415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11415"/>
    <dbReference type="EnsemblBacteria" id="AQP45329">
        <property type="protein sequence ID" value="AQP45329"/>
        <property type="gene ID" value="RPIT_11415"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11415"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh_C" evidence="2">
        <location>
            <begin position="105"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="356" mass="37330" checksum="3B0A247E36B1F645" modified="2017-04-12" version="1">MSAERLKVLLPSSLPLDPQLPPGVEAIAYDPEQPVPVEHRDAEVLVVWGNRGRHLREAAQHMPNLRLVQGLMAGPDQLLRVGFGPDVTICSGVGLHDQTVSEHALALVLALVRRVPQSLAAQREHRWATELAGAQPLRPAGPITTMLDARVLIWGFGSIGTTLAPLLAAMGATVTGAARSAGERAGFRVVDDSGLAAELARTDILVMLLPASEHTENALNAERLRQLKRDAYLVNVGRGVTVDETALLDALASGRLGGAALDVMQTEPLPPDSPLWDAPNVLLTPHNAGGRPVGVDDLIATNVRALLAGGACATSWPDRPATIERQGSSTGGSGGVVAVRSDGRAPISCSASPVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGT8</accession>
    <name>A0A1Q2CGT8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Carbohydrate ABC transporter membrane protein 2, CUT1 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Thiamine ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">RPIT_11400</name>
        <name evidence="8" type="ORF">SAMN05428934_10224</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1T</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">RP1</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY48702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45326">
        <property type="protein sequence ID" value="AQP45326"/>
        <property type="gene ID" value="RPIT_11400"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY48702">
        <property type="protein sequence ID" value="SDY48702"/>
        <property type="gene ID" value="SAMN05428934_10224"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11400"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="203"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="91"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AQP45326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY48702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="296" mass="31792" checksum="C4FF10C3925C2673" modified="2017-04-12" version="1">MSQVALTSRGRKARRPYGGTSRKSSVPWGKPSVYLIATVLIAICIGPVLYIILGGFRSNAQITTDPSGMPNPWVFSNYTEVLTAGTFWQQFGNSVISAVLTTVGCVSLALAASYVIARYNFRGRNAMFSLFAAGLMFPMTVAITPLYILIRSLGLTNTLAGIILPQIGFALPVTVIILVPFLRAIPKEIEEAAMIDGSGRVGFFFRMVLPLSLPGVITTGILAFIGAWNNYMLPLFILSDPAKYTLPLGVQAFASQYSVNTAAVLAFTSLSMLPALLFFSVFERRIVGGLTGAIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CGY0</accession>
    <name>A0A1Q2CGY0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Two-component system, OmpR family, response regulator RegX3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_11310</name>
        <name evidence="7" type="ORF">SAMN05428934_10241</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000002">
        <property type="protein sequence ID" value="SDY49280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_11310"/>
    <dbReference type="EnsemblBacteria" id="AQP45310">
        <property type="protein sequence ID" value="AQP45310"/>
        <property type="gene ID" value="RPIT_11310"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY49280">
        <property type="protein sequence ID" value="SDY49280"/>
        <property type="gene ID" value="SAMN05428934_10241"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11310"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="126"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="126"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP45310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDY49280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="225" mass="25287" checksum="ABBCA0559D765765" modified="2017-04-12" version="1">MTRILIIEDEDSYRDATSFMLRKEGFEVATAADGAEGLAEYDRSGADLVLLDLMMPGMSGVEVCRQLRSRGNVAIVMVTARDSEVDKVVGLEIGADDYVTKPFSHRELVARIRAVLRRGQDQVLLPEVVEADGVRVDVERHQVTVDGVEVRFALREFELLELLLRNAGRVMTRGQLIDRIWGSDYVGDTKTLDVHIKRLRSKIEKDPANPQRLITVRGLGYKYEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH58</accession>
    <name>A0A1Q2CH58_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HIT family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Histidine triad (HIT) family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_11810</name>
        <name evidence="4" type="ORF">SAMN05428934_106113</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1T</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY93150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45400">
        <property type="protein sequence ID" value="AQP45400"/>
        <property type="gene ID" value="RPIT_11810"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY93150">
        <property type="protein sequence ID" value="SDY93150"/>
        <property type="gene ID" value="SAMN05428934_106113"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_11810"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46648">
        <property type="entry name" value="PTHR46648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="8"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="1">
        <location>
            <begin position="98"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SDY93150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="140" mass="15230" checksum="0C8630FD4838B097" modified="2017-04-12" version="1">MDPGDRDVVCGVVAGAVDADVVYRDDTVIAFLDHRPVFKGHVLVCPITHVDTLLDLPAELISPLFGVVQRVANAMEEALGAQGSFTAINTVVSQSVPHLHVHVVPRTRGDGLRGFFWPRTRYAETEAAEYAARLRAALTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CH98</accession>
    <name>A0A1Q2CH98_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycerophosphoryl diester phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_12285</name>
        <name evidence="3" type="ORF">SAMN05428934_10619</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1T</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000006">
        <property type="protein sequence ID" value="SDY91078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12285"/>
    <dbReference type="EnsemblBacteria" id="AQP45484">
        <property type="protein sequence ID" value="AQP45484"/>
        <property type="gene ID" value="RPIT_12285"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY91078">
        <property type="protein sequence ID" value="SDY91078"/>
        <property type="gene ID" value="SAMN05428934_10619"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12285"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GP-PDE" evidence="1">
        <location>
            <begin position="2"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY91078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="242" mass="26815" checksum="E7AD78A2F1535B6C" modified="2017-04-12" version="1">MTAIWGHRGASAYAPENTLASFQQAIQLGVDGVELDVQRTADGHIVAIHDESVNRTSNGFGRVVDMTLDELRHLDFAHGFAGRRNVKIPTLQEVLELFRETTLTVNIELKNTIVLYPGMEDDVVRIVNEFGMLDRVIISSFNHYSLANLRGKIPPQHVGALTSDGLFEPWRYVSWLGAGAIHPHFAALQQPDYVWLCHEAGIKVHTWTVNKDEDAIALAAKGVDAIITNLPDRVARAVHGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHC8</accession>
    <name>A0A1Q2CHC8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_12465</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45514">
        <property type="protein sequence ID" value="AQP45514"/>
        <property type="gene ID" value="RPIT_12465"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12465"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="110" mass="12158" checksum="5D17289D328F7489" modified="2017-04-12" version="1">MDTDRLQRPPIRDVFPVAAMTVARLLAALDSQVTLTLDDGDDFDRHIDARAGKDLDRLARVGLYTGDTDQGFVAPLGSQRPNHVIAPSDWRYSHMAGRLVICDLRLRSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHF6</accession>
    <name>A0A1Q2CHF6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-2 type transport system ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Multidrug ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">RPIT_12605</name>
        <name evidence="6" type="ORF">SAMN05428934_104165</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY79605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP45541">
        <property type="protein sequence ID" value="AQP45541"/>
        <property type="gene ID" value="RPIT_12605"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY79605">
        <property type="protein sequence ID" value="SDY79605"/>
        <property type="gene ID" value="SAMN05428934_104165"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12605"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDY79605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="308" mass="32634" checksum="D594B046F56ED71A" modified="2017-04-12" version="1">MIEARHLIKHYGETVAVDGISFDVQPGRVTGFLGPNGAGKSTTMRMIVGLDRPTSGTVTVGGKAYRDHRSPLTQVGVLLDAKAVHSGRSAYQHLRAMAATHGISRDRVAEVIRITGLEQVAGRRVGGFSLGMGQRLGIAAALLGDPQTLILDEPVNGLDPEGVKWVRTLVRRLADDGRTVFLSSHLMSEMAQTADHLVVIGRGRIIADGPIDDILTRATTPTVRVATPDAGTLAPLLIVRGATVRTLPTGQLEVTDLPAPAVGDLAAANGVALHELTPVRASLEEAFMELTRDSVEYRSEPTAEGISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHG9</accession>
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            <fullName evidence="3">N-acetylglucosaminyl deacetylase, LmbE family</fullName>
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        <name evidence="3" type="ORF">SAMN05428934_104198</name>
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    </organism>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">RP1T</strain>
        </source>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">RP1</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45510.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY80487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="222" mass="23493" checksum="C2B9DE8329230169" modified="2017-04-12" version="1">MQLPPLPHVLAVVAHPDDESFGLGAVISTLIDAGSQVSVLCLTSGEASTLGAHPDLARIRALELETAAAALGCHNTTLLAHPDGGLSQYPELLVRDVELAADTVQPDAFLVFSPEGGVTGHPDHEAASRAALAVAAERGLPTLEWALPLHVTDALAEEYGVAFTGYRESELPIVLEVDRTRQLAAAAEHASQAVPGSLLWRRLELLGNHEYLRLTDPTQENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHI4</accession>
    <name>A0A1Q2CHI4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">RPIT_12825</name>
        <name evidence="2" type="ORF">SAMN05428934_104122</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
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    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">RP1T</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">RP1</strain>
        </source>
    </reference>
    <reference evidence="1" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">RP1T</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="AQP45579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="AQP45579"/>
        <property type="gene ID" value="RPIT_12825"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY78332"/>
        <property type="gene ID" value="SAMN05428934_104122"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12825"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AQP45579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SDY78332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="602" mass="68701" checksum="319265905DEC135E" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHJ5</accession>
    <name>A0A1Q2CHJ5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Simple sugar transport system substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_12840</name>
        <name evidence="5" type="ORF">SAMN05428934_104119</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Propionibacteriales</taxon>
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    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">RP1T</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY78259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12840"/>
    <dbReference type="EnsemblBacteria" id="AQP45582">
        <property type="protein sequence ID" value="AQP45582"/>
        <property type="gene ID" value="RPIT_12840"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY78259">
        <property type="protein sequence ID" value="SDY78259"/>
        <property type="gene ID" value="SAMN05428934_104119"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_12840"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Peripla_BP_I"/>
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        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
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        <location>
            <begin position="24"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="3">
        <location>
            <begin position="82"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP45582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SDY78259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="363" mass="37097" checksum="95E0759C78AB4D63" modified="2017-04-12" version="1">MLTKFLRLFIAALASMLVLTACGEGDTASPGDTPASETTMAEAPTETTEPADPADPTTTPADDESTPAAGGEPLTIGLVMLQGDDYFRNVQLGMEEAVSADGGTVIPFNSNNDPGNEAQGVQNLITRAVDGITMQPVAADASVATARLVKDAGIPLICTGNCTGAFLTPELVDGAAQSDNTGLGTATGEAAAEYIEANLGGTATVGILNCDSAAETCKLRKAGFIKALEDAGIDFTIAADQEGYLADRATPVATNMLSSNPAINVVWGSNEGGTVALVTAVKQAGADVAVFGTDISEQIAGFVKEGSLEATTGQDPAGTSAKAYEMVKKAINGETNEPFEALIPGITYRTDDQTTVDEYLANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHM3</accession>
    <name>A0A1Q2CHM3_9ACTN</name>
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        <recommendedName>
            <fullName evidence="4 11">L-aspartate oxidase</fullName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">RPIT_12790</name>
        <name evidence="15" type="ORF">SAMN05428934_104129</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">RP1T</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">RP1</strain>
        </source>
    </reference>
    <reference evidence="14" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-aspartate + O2 = H2O2 + iminosuccinate</text>
            <dbReference type="Rhea" id="RHEA:25876"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
            <dbReference type="EC" id="1.4.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:25877"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (oxidase route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.16" evidence="4 11"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000004">
        <property type="protein sequence ID" value="SDY78545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_12790"/>
    <dbReference type="EnsemblBacteria" id="AQP45573">
        <property type="protein sequence ID" value="AQP45573"/>
        <property type="gene ID" value="RPIT_12790"/>
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    </dbReference>
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    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
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            <end position="390"/>
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</entry>
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            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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            <strain evidence="6 8">RP1T</strain>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
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        </source>
    </reference>
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        <location>
            <begin position="42"/>
            <end position="468"/>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="SDY76451.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="626" mass="70437" checksum="245FFA615E583313" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CHR2</accession>
    <name>A0A1Q2CHR2_9ACTN</name>
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        </recommendedName>
    </protein>
    <gene>
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        <name evidence="11" type="ORF">SAMN05428934_10434</name>
    </gene>
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        <lineage>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">RP1T</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">RP1</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">RP1T</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
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        </reaction>
    </comment>
    <comment type="similarity">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="SAMN05428934_10434"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Alpga-gal_N_sf"/>
    </dbReference>
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        <property type="entry name" value="Glyco_hydro_27/36_CS"/>
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    <dbReference type="InterPro" id="IPR013780">
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    </dbReference>
    <dbReference type="Pfam" id="PF16875">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Agal"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_36N" evidence="9">
        <location>
            <begin position="25"/>
            <end position="269"/>
        </location>
    </feature>
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        <location>
            <begin position="628"/>
            <end position="728"/>
        </location>
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            <begin position="347"/>
            <end position="348"/>
        </location>
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        <location>
            <begin position="457"/>
            <end position="461"/>
        </location>
    </feature>
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        <location>
            <position position="459"/>
        </location>
    </feature>
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        <location>
            <position position="525"/>
        </location>
    </feature>
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        </location>
        <ligand>
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        <ligand>
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        <ligand>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012755"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PIRNR" id="PIRNR005536"/>
        </source>
    </evidence>
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        <source>
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        </source>
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    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR005536-2"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF16874"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF16875"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="AQP45659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY75928.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
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    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="747" mass="82019" checksum="BD8B36B80FD59C5F" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI01</accession>
    <name>A0A1Q2CI01_9ACTN</name>
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        <submittedName>
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        </submittedName>
        <submittedName>
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    <organism evidence="5 7">
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    </organism>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">RP1T</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="gene ID" value="SAMN05428934_11145"/>
    </dbReference>
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    </dbReference>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022679"/>
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            <dbReference type="Pfam" id="PF00534"/>
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            <dbReference type="Pfam" id="PF13579"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AQP45742.1"/>
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    </evidence>
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            <dbReference type="EMBL" id="SDZ12427.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="392" mass="42102" checksum="79B6D355DFBA2627" modified="2017-04-12" version="1">MGVRPVPGRKRLVVGVTVGMSADLLLRGQLAWFRERGWDVTLISTPDDQAQRAATREGVELLGIPMARGISPLSDLTGLVAWVRALRRLRPDAVNVGTPKAALLGSIAAWLTRVPRRLYTVRGLRLEGSSGPLSRVLWLMEWVTMRAATDVLFVSASLAEEAVRRRLPIAGKKRLIGQGSSNGVDAAAVQTRVSQVDRDALRAELGLSDEDFVVGFVGRINPDKGTDVIARASRSAELDPRVKFLMIGSLESPELRAGLASPDSRLRHVEWTDDVWGHLAAMDALCLPTLREGFPNVVLEAAAAGLPVVTTTATGAVDSVVDGETGFLIPVGDDAALVARLNTLADQPDLAASMGAAGRQRVLEHFGQEQIWRGIEHILTGHTTHDTKGVIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI17</accession>
    <name>A0A1Q2CI17_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HpcH_HpaI domain-containing protein</fullName>
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    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_13935</name>
    </gene>
    <organism evidence="3 4">
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000188324">
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF03328">
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="8"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="149" mass="15780" checksum="7E862B7B3B711E6D" modified="2017-04-12" version="1">MTLMYITKDPVVAKIAEDGGVDWVFVDLEIHGKMARQGHLDTVISDHTFEDVRAVAEVLTTSQLLVRVNPVHEGSAEEIDTVIAAGAQILMLPYFTHRGEVAEFISLISGRAQVCLLLETPGAVEASATGCSSCLSSSPTAPSRASAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CI97</accession>
    <name>A0A1Q2CI97_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">RPIT_14025</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
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    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="AQP45780">
        <property type="protein sequence ID" value="AQP45780"/>
        <property type="gene ID" value="RPIT_14025"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14025"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="1"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="282"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="315"/>
            <end position="322"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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            <dbReference type="PROSITE" id="PS50929"/>
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    </evidence>
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            <dbReference type="EMBL" id="AQP45780.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="521" mass="55294" checksum="47D7EA184F857184" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
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            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            </authorList>
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            <end position="75"/>
        </location>
    </feature>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="80" mass="8771" checksum="0703C176F23438E5" modified="2017-04-12" version="1">MVYGQTVELRADPTQDDTDRYGRLLRHVYIDGQSAAVVLLEAGAAHEYTYDAPYIGQAEHRDAEHTAQADALGMWGSCTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
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            <dbReference type="PubMed" id="26869509"/>
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            <dbReference type="EMBL" id="AQP45894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="75" mass="8216" checksum="5A5C25059EBC0877" modified="2017-04-12" version="1">MHQATTGCCRPSADAGRTFRNREAIIRLVGAVLAEQTDEWAEGRRYLGLDVLARCRLSTITNAVEEVTEPLALTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIK0</accession>
    <name>A0A1Q2CIK0_9ACTN</name>
    <protein>
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        <submittedName>
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        </submittedName>
    </protein>
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    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
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                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6 8">RP1T</strain>
        </source>
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    <reference evidence="7 9" key="2">
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            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 9">RP1</strain>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </source>
    </reference>
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    </dbReference>
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    </evidence>
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            <dbReference type="EMBL" id="SDZ06033.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="359" mass="39021" checksum="95F16727EA159B80" modified="2017-04-12" version="1">MAKQAAANFIEVERWTAESGPLLDVRDLTVEFRTREGVAKAINGASFTLDRGESLAILGESGSGKSVTAQAIMGILDSPPGFVTGGEVMFRGVDLLKLPEDKRRQVRGRRISMIFQDALSALNPVFTVGWQIAEMFRIHKGMNRSDARDAAVQLMERVNIPAARERAGNFPHQFSGGMRQRIMIAMAIALDPEILIADEPTTALDVTVQAQIMDLLRELQAETGMGLILITHDLGVVADVADRINVMYAGRMVEKADVLDLYSNPAHPYTEGLLESIPRLDQTTGDLQAIGGLPPNLTKIPPGCAFNPRCRYARDICKVDPVPPVIDLGNGRTSACHFTRELLAGSLTPTVSSTEVTDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIL4</accession>
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        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 5" key="2">
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
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                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45978.1"/>
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    </dbReference>
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        <property type="protein sequence ID" value="SDY25882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="RPIT_02600"/>
    </dbReference>
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        <property type="protein sequence ID" value="SDY25882"/>
        <property type="gene ID" value="SAMN05428934_101120"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_02600"/>
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        <property type="component" value="Chromosome"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase"/>
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        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
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        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53474"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="6"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP45978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SDY25882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="215" mass="23184" checksum="55AE44955F4A03AF" modified="2017-04-12" version="1">MSSAQQWADYPALLPEFDVVAIDLPGHGSKSGTPFTTEAALDAIAEAVDGAVPVVLAGHSLGAYLVGLFAGTRPHRLRGLVLMGATGNPRGRLAWTYRGFAGLTRRVDHSVLARLRGGVARLLGVRPELLPARPDYTTLPAIWESVMRDCPPSVLRSVGCPVLFINGQFDQMRADERRYLARVEGSALEIVPRASHFAPLTHAPEVAEAIRRFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIR1</accession>
    <name>A0A1Q2CIR1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">RPIT_03845</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_03845"/>
    <dbReference type="EnsemblBacteria" id="AQP46001">
        <property type="protein sequence ID" value="AQP46001"/>
        <property type="gene ID" value="RPIT_03845"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_03845"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13462">
        <property type="entry name" value="Thioredoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012862879" description="Thioredoxin domain-containing protein" evidence="2">
        <location>
            <begin position="30"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="39"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AQP46001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="249" mass="26611" checksum="AB9BE42ED5A84CC3" modified="2017-04-12" version="1">MVYKAVIVGLVLVVVVLGGLLAMRPGTPAAVPAPAATSTPPATPAPDQPAPQPSIDPQQVAEMERFMVEDLPRRIEGDPLAMGNIDAPVVLTEWADYRCPFCSVWAEDVLPGLQRYIDDGTLRVEFRDLAIFGDESIRAATAARAAGEQGQFFEFSHELFSALPNEGHPDIPDELVYGIVADLGLDRATFEADWADPAHQEAVLADSAEANGFGVTSTPSFVIGSQFVSGAQPLSTFEQIIEEQLALHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIR3</accession>
    <name>A0A1Q2CIR3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">7,8-dihydroneopterin aldolase</fullName>
            <ecNumber evidence="1">4.1.2.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_01580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7,8-dihydroneopterin = 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde</text>
            <dbReference type="Rhea" id="RHEA:10540"/>
            <dbReference type="ChEBI" id="CHEBI:17001"/>
            <dbReference type="ChEBI" id="CHEBI:17071"/>
            <dbReference type="ChEBI" id="CHEBI:44841"/>
            <dbReference type="EC" id="4.1.2.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DHNA family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.25" evidence="1"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP45963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_01580"/>
    <dbReference type="EnsemblBacteria" id="AQP45963">
        <property type="protein sequence ID" value="AQP45963"/>
        <property type="gene ID" value="RPIT_01580"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_01580"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00154"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004150">
        <property type="term" value="F:dihydroneopterin aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00534">
        <property type="entry name" value="DHNA_DHNTPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006156">
        <property type="entry name" value="Dihydroneopterin_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006157">
        <property type="entry name" value="FolB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42844">
        <property type="entry name" value="PTHR42844"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02152">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00905">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00525">
        <property type="entry name" value="folB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00526">
        <property type="entry name" value="folB_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FolB" evidence="2">
        <location>
            <begin position="5"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP45963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="119" mass="12971" checksum="6E125E35CAC0845E" modified="2017-04-12" version="1">MIDAITITGLTATGFHGVFPEERREGQPFVVDVVLELPLETSSDDLADTVSYADIADDVEAVITGEPRNLIETVAGEIAERCLLRGRVDRVTVTVHKPRAPLSQTFADVSVTINRSRHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIY2</accession>
    <name>A0A1Q2CIY2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pribosyltran domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_05345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_05345"/>
    <dbReference type="EnsemblBacteria" id="AQP46033">
        <property type="protein sequence ID" value="AQP46033"/>
        <property type="gene ID" value="RPIT_05345"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_05345"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pribosyltran" evidence="1">
        <location>
            <begin position="182"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="245" mass="25601" checksum="24CF0E1835FFA20A" modified="2017-04-12" version="1">MTVSLCGCGYRDPTGGGTDDARVRSLLDAAADLLLGASCPACSRPGWGLCRDCTEALVMPVRVLDRGLPVPLYAACPYRPLLQRVVPSYKDDGALHLARPLGSLLARAVAAHDLPSGTRLVPVPSLPAAVRARGFDHAAALCAEAARVSGIPMARRVLRRSGRGRDQRGLSRAARQANLADSMLARDPGVPVLLIDDVATTGASLREALRALQAAGVVVVGAAVLADADDARSGQRIRRHLLVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CIY6</accession>
    <name>A0A1Q2CIY6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH tetR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_07615</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP46077">
        <property type="protein sequence ID" value="AQP46077"/>
        <property type="gene ID" value="RPIT_07615"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_07615"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="199" mass="21148" checksum="C10D06BBA9827239" modified="2017-04-12" version="1">MRADGRRTRAAILQTAARLASVDGIEGLTIGGLAAELHMSKSGLYAHFGSKVELQLATVAEAARIFDDVVVAPAMAAPSAHEQLLALCDRYLQHLRDRVFPGGCFFASAALEMGSRPGPVREAIADFQRRLTGLFAQLVVAAQREGRLLGEDPRALAFEINGQFLAASAGFVLTGDAGVLDLAEQVLFRRLGHAVAPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ16</accession>
    <name>A0A1Q2CJ16_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease 3</fullName>
            <ecNumber evidence="6">3.1.26.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Ribonuclease III</fullName>
            <shortName evidence="6">RNase III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rnc</name>
        <name evidence="10" type="ORF">RPIT_08685</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">RP1T</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribonuclease III family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.3" evidence="6"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_08685"/>
    <dbReference type="EnsemblBacteria" id="AQP46094">
        <property type="protein sequence ID" value="AQP46094"/>
        <property type="gene ID" value="RPIT_08685"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_08685"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00104">
        <property type="entry name" value="RNase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011907">
        <property type="entry name" value="RNase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207">
        <property type="entry name" value="PTHR11207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14622">
        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="SSF69065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02191">
        <property type="entry name" value="RNaseIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="RNase III" evidence="9">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="8">
        <location>
            <begin position="150"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AQP46094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="222" mass="23879" checksum="D4695D9C7DBA0EEF" modified="2017-04-12" version="1">MEQLGIEVDAQLFELSFTHRSYAYENGGVPSNERLEFLGDAVLQIVVTEHIFRTYPDLAEGQLAKLRASVVSAVALAEVARSLDLGSLLLLGKGELTTGGRDKTSILADTFEAVIGAIHLSCGPDASSRFIHALFDPLIASAEHRGDYTDHKTALQEICAQRGWSPPRYEITGTGPDHQRVFTATVVLDERPFGSGSAPSKKQAEQIAARAAFRELSGAGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ32</accession>
    <name>A0A1Q2CJ32_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4440 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">RPIT_10800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_10800"/>
    <dbReference type="EnsemblBacteria" id="AQP46129">
        <property type="protein sequence ID" value="AQP46129"/>
        <property type="gene ID" value="RPIT_10800"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_10800"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027843">
        <property type="entry name" value="DUF4440"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011944">
        <property type="entry name" value="Steroid_delta5-4_isomerase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14534">
        <property type="entry name" value="DUF4440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02246">
        <property type="entry name" value="TIGR02246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4440" evidence="2">
        <location>
            <begin position="10"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AQP46129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="158" mass="17274" checksum="E508C05679290988" modified="2017-04-12" version="1">MKLTDPLDIARGFLEAWNDQDPDALAALFTDDADFVNVVGLWWEDRPSIRRAHARGFRVMFGGSEMTLERTKVRRLGADAAVVHALWSMTGQVDPAGSPVGDRSGVLSFVVERQPDGGWLAVAAHNTDRFPAAETLVAEPSGQLEPTSYVPRAERNDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ34</accession>
    <name>A0A1Q2CJ34_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_06780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP46060">
        <property type="protein sequence ID" value="AQP46060"/>
        <property type="gene ID" value="RPIT_06780"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_06780"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="98" mass="9842" checksum="A3725772D199744C" modified="2017-04-12" version="1">MAGIGVGSAIANSKLFGIGVAAVLVGYGAAMIALSWLVIRGRAWAMGLVVAAALLHLLVVGSFLTTDDRAQFLGSLAVLPVILATVIAGVVSIGRRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJ84</accession>
    <name>A0A1Q2CJ84_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Biotin carboxylase</fullName>
            <ecNumber evidence="2">6.3.4.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">RPIT_09685</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">RP1T</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="6.3.4.14" evidence="2"/>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_09685"/>
    <dbReference type="EnsemblBacteria" id="AQP46110">
        <property type="protein sequence ID" value="AQP46110"/>
        <property type="gene ID" value="RPIT_09685"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_09685"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0092">Biotin</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="11">
        <location>
            <begin position="1"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="10">
        <location>
            <begin position="119"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="9">
        <location>
            <begin position="507"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="482"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AQP46110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="586" mass="62079" checksum="8C677B5A924D4FC2" modified="2017-04-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJG4</accession>
    <name>A0A1Q2CJG4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">RPIT_14445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">RP1T</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1610493.RPIT_14445"/>
    <dbReference type="EnsemblBacteria" id="AQP46190">
        <property type="protein sequence ID" value="AQP46190"/>
        <property type="gene ID" value="RPIT_14445"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14445"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005451">
        <property type="term" value="F:monovalent cation:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098662">
        <property type="term" value="P:inorganic cation transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005133">
        <property type="entry name" value="PhaG_MnhG_YufB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34703">
        <property type="entry name" value="PTHR34703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03334">
        <property type="entry name" value="PhaG_MnhG_YufB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01300">
        <property type="entry name" value="CPA3_mnhG_phaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AQP46190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <sequence length="121" mass="12850" checksum="DC12A2E4E942B0E2" modified="2017-04-12" version="1">MDATFDLIGALLMLVGAGLCFAAAVALVRFPDVMSKMHAVTKPQVLGLIAISLGIGLSLRTWWASGLCILIVVVQLLTAPVSANLVARGAYRAGLANDSKLKYNHLAEDLKEAGYTRPEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-04-12" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Q2CJH9</accession>
    <name>A0A1Q2CJH9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hemolysin III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">RPIT_14830</name>
        <name evidence="7" type="ORF">SAMN05428934_10954</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Tessaracoccus flavus</name>
        <dbReference type="NCBI Taxonomy" id="1610493"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Propionibacteriales</taxon>
            <taxon>Propionibacteriaceae</taxon>
            <taxon>Tessaracoccus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2016" name="Int. J. Syst. Evol. Microbiol." volume="66" first="1862" last="1868">
            <title>Tessaracoccus flavus sp. nov., isolated from the drainage system of a lindane-producing factory.</title>
            <authorList>
                <person name="Kumari R."/>
                <person name="Singh P."/>
                <person name="Schumann P."/>
                <person name="Lal R."/>
            </authorList>
            <dbReference type="PubMed" id="26869509"/>
            <dbReference type="DOI" id="10.1099/ijsem.0.000958"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">RP1T</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">RP1</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-02" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Peterson S.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">RP1T</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP019605">
        <property type="protein sequence ID" value="AQP46195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNPU01000009">
        <property type="protein sequence ID" value="SDZ05621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="AQP46195">
        <property type="protein sequence ID" value="AQP46195"/>
        <property type="gene ID" value="RPIT_14830"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDZ05621">
        <property type="protein sequence ID" value="SDZ05621"/>
        <property type="gene ID" value="SAMN05428934_10954"/>
    </dbReference>
    <dbReference type="KEGG" id="tfl:RPIT_14830"/>
    <dbReference type="Proteomes" id="UP000188324">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000199635">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="PTHR20855"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AQP46195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDZ05621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000188324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000199635"/>
        </source>
    </evidence>
    <sequence length="221" mass="24245" checksum="BC7E0B2B1182183E" modified="2017-04-12" version="1">MRSRDGSVHVTDERFNTLSHLVAFCFSVLGAVLLVSQSVAQGDPWKIVGFSVYGLALMTLFAASTLHHGLDRGPRVNEALRTLDYASVFLVIAGTVTPLVLVLVRTVYGWAVFGAVWAVAILGIVLRSVWRRLPKYVTNTLYITLGWMTIALLGGDVSLPPMALVLLAAGGLVYSAGFVIYVIERPNPWPGKFGFHELWHILVGLAAMLHYLLMYFFVLPA</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>